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Oxytocin acetate is a mammalian neurohypophysial hormone. Its actions are mediated by specific, high-affinity oxytocin receptors. Oxytocin is normally produced in the hypothalamus and stored in the posterior pituitary gland, which plays a role in intimacy, sexual reproduction of both sexes, and during and after childbirth. Synonyms: (S)-N-((S)-1-((2-amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-((S)-sec-butyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamide acetate; Orasthin; Ossitocina; Ossitocina; Oxetakain; Oxitocina; Oxoject; Oxystin; Partocon; Pitocin; Piton S; Oxt,; Oxytocin. Grades: >98%. CAS No. 6233-83-6. Molecular formula: C45H70N12O14S2. Mole weight: 1067.24.
Oxytocin acetate
Oxytocin (α-Hypophamine) acetate is a pleiotropic, hypothalamic peptide known for facilitating parturition, lactation, and prosocial behaviors. Oxytocin acetate can function as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects especially in the face of adversity or trauma [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: α-Hypophamine acetate; Oxytocic hormone acetate. CAS No. 6233-83-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17571A.
The principal uterus-contracting and lactation-stimulating hormone of the posterior pituitary gland. Group: Biochemicals. Alternative Names: L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucyl-glycinamide Cyclic (1-6)-Disulfide; Hyphotocin; Intertocine S; Orasthin Acetate; Oxytocin Monoacetate; Perlacton Acetate; Pitocin Acetate; Syntocinon Acetate; Synpitan Acetate; Uteracon Acetate. Grades: Highly Purified. CAS No. 6233-83-6. Pack Sizes: 10mg. US Biological Life Sciences.
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Oxytocin C-terminal tripeptide acetate
Oxytocin C-terminal tripeptide acetate, an inhibitor of melanocyte-stimulating hormone (MSH) release, blocks the release of α-MSH, increases brain dopamine levels, and antagonizes physiological and behavioral opioid effects in vivo. Synonyms: H-Pro-Leu-Gly-NH2.CH3CO2H; PLG-NH2.CH3CO2H; L-prolyl-L-leucyl-glycinamide acetic acid; Glycinamide, L-prolyl-L-leucyl-, acetate (1:1); L-Prolyl-L-leucylglycinamide acetate. Grades: ≥95%. CAS No. 1207536-22-8. Molecular formula: C15H28N4O5. Mole weight: 344.41.
Atosiban acetate
Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: RW22164 acetate; RWJ22164 acetate. CAS No. 914453-95-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17572A.
Atosiban Acetate
Atosiban Acetate is an oxytocin receptor blocking agent in the treatment of experimental endometriosis and is shown exhibit significant therapeutic efficiency. It is clinically used to decrease uterine contractility in the prevention of pre-term birth. Synonyms: Cyclic (1?5)-disulfide O-Ethyl-N-(3-mercapto-1-oxopropyl)-D-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithyl-glycinamide Monoacetate; Antocile Acetate; CAP 449 Acetate; CAP 476 Acetate; CAP 581 Acetate; F 314 Acetate; ORF 22164 Aceta. Grades: > 95%. CAS No. 914453-95-5. Molecular formula: C45H71N11O14S2. Mole weight: 1054.26.
Carbetocin acetate
Carbetocin acetate, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a K i of 7.1 nM. Carbetocin acetate has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (K i =1.17 μM). Carbetocin acetate has the potential for postpartum hemorrhage research. Carbetocin acetate can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 1631754-28-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17573A.
Lysipressin
Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels. Synonyms: Lys(8)-Vasopressin; Lys(8)-AVP; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide; Vasopressin, 8-L-lysine-; 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide, 19-amino-4-[2-[[5-amino-1-[ (carbamoylmethyl) carbamoyl]pentyl]carbamoyl]-1-pyrrolidinylcarbonyl]-13-benzyl-7- (carbamoylmethyl) -16-p-hydroxybenzyl-6, 9, 12, 15, 18-pentaoxo-; 8-L-Lysinevasopressin; 3-(Phenylalanine)-8-lysine oxytocin; 8-L-Lysine vasopressin; L-Lysine vasopressin; [8-Lysine]vasopressin; Diapid; Lysine pitressin; Lysine vasopressin; Lysine-ADH; Lysylvasopressin; Oxytocin, 3-(L-phenylalanine)-8-L-lysine-; Postacton; Syntopressin; Vasophysin; Vasopressin-8-lysine; Lysine-AVP. Grades: 98%. CAS No. 50-57-7. Molecular formula: C46H65N13O12S2. Mole weight: 1056.22.
Oxytocin
Oxytocin is a mammalian neurohypophysial hormone. It plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes, in particular during and after childbirth. It is released in large amounts after distension of the cervix and uterus during labor, facilitating birth, maternal bonding, and, after stimulation of the nipples, lactation. Uses: Oxytocics. Synonyms: 3-Isoleucine-8-leucine vasopressin; Alpha-hypophamine; Atonin O; Di-sipidin; Endopituitrina; Hyphotocin; Intertocine S; Nobitocin S; Orasthin; Partocon; Perlacton; Pitocin; Piton S; Presoxin; Synpitan; Synpitan forte; Synthetic oxytocin; Syntocin; Syntocinon; Syntocinone; Uteracon; Vasopressin, 3-L-isoleucine-8-L-leucine-; [1-Hemicystine]-oxytocin; a-Hypophamine; Oxytocin Acetate; Oxytocin Acetate USP30. Grades: >98%. CAS No. 50-56-6. Molecular formula: C43H66N12O12S2. Mole weight: 1007.19.
Vasopressin Acetate
An impurity of Vasopressin. Vasopressin is a neurohypophysial hormone existing in most mammals. It has the function of regulating body's water retention via antidiuretic activity. Vasopressin is a peptidic V1a receptor agonist that can increase blood pressure by contracting the blood vessels. Uses: Oxytocics. Synonyms: VASOTOCIN; 9034-50-8; Vasopressin acetate; [Arg8]-vasotocin; 1-[19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-butan-2-yl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide; Arginine oxytocin; 113-80-4; Vasopressin, isoleucyl; CYS-TYR-ILE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 ACETATE SALT; 3-Isoleucyl vasopressin; Vasopressin, non-mammalian; SCHEMBL15511347; Vasotocin; DL-cysteinyl-DL-tyrosyl-DL-isoleucyl-DL-glutaminyl-DL-asparagyl-DL-cysteinyl-DL-prolyl-DL-arginyl-glycinamide (1->6)-disulfide. Molecular formula: C46H65N15O12S2. nC2H4O2. Mole weight: 1084.25 (free base).
Ac-Oxytocin
Ac-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: Acetyl-L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); Cys(Ac)-Oxytocin; Ac-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, N-acetyl-; N(alpha)-Acetyloxytocin; N-Acetyloxytocin; Oxytocin, 1-(N-acetylcysteine). Grades: ≥95%. CAS No. 10551-48-1. Molecular formula: C45H68N12O13S2. Mole weight: 1049.23.
(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin is a potent and selective oxytocin antagonist in vivo. Synonyms: dGVTA; β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Ile-Thr-Asn-Cys-Pro-Orn-OH; OTA (dOVT); 2-O-methyltyrosyl-4-threonyl-8-ornithyl-9-desglycinamide-vasotocin; desGly(9)-d(CH2)5(Tyr(Me)(2)-Thr(4))OVT; (1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid),2-O-methyltyrosine,4-threonine,8-ornithine)vasotocin; Methyl N-[(2-thioxocyclohexyl)acetyl]-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-ornithinate; L-Ornithine, N-[2-(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-isoleucyl-L-threonyl-L-asparaginyl-L-cysteinyl-L-prolyl-, cyclic (1?5)-disulfide; (d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin. Grades: ≥95% by HPLC. CAS No. 115499-13-3. Molecular formula: C45H69N9O12S2. Mole weight: 992.21.
Guanosine 3',5'-cyclic monophosphate
Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'-and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. 3',5'-cyclic GMP is a 3',5'-cyclic purine nucleotide in which the purine nucleobase is specified as guanidine. It has a role as a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a guanyl ribonucleotide and a 3',5'-cyclic purine nucleotide. It is a conjugate acid of a 3',5'-cyclic GMP(1-). Synonyms: D-Guanosine 3',5'-cyclic monophosphate; 3',5'-cyclic GMP; 2-Amino-6-oxo-6,9-dihydro-1H-purine 3-oxide; guanine-3-N-oxide; 2-Amino-1,7-dihydro-6H-purin-6-one 3-oxide; Cyclic guanosine monophosphate; 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-1H-purin-6-one. Grades: ≥ 95%. CAS No. 7665-99-8. Molecular formula: C10H12N5O7P. Mole weight: 345.21.
L-371,257
L-371,257 is a potent and high affinity human oxytocin (OT) receptor antagonist with Ki value of 4.6 nM. It displays > 800-fold selectivity over human arginine vasopressin receptors V1a and V2. It antagonizes oxytocin-induced contractionsin in anesthetised rats following intravenous and intraduodenal administration. It also inhibits oxytocin-induced contractionsin in isolated rat uterine tissue. It decreases length of U-87MG cell projections induced by retinoic acid. It is orally active. Synonyms: L-371,257; L 371,257; L371,257; 1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one; 1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine. Grades: ≥99% by HPLC. CAS No. 162042-44-6. Molecular formula: C28H33N3O6. Mole weight: 507.59.
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