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Pemetrexed Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 3140-73-6. Molecular Formula: C5H6ClN3O2. Mole Weight: 175.57. Catalog: APB3140736.
Pemetrexed Impurity 10
Pemetrexed Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H16N4O3. Mole Weight: 312.33. Catalog: APB10801.
Pemetrexed Impurity 11
Pemetrexed Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 193265-47-3. Molecular Formula: C15H14N4O4. Mole Weight: 314.3. Catalog: APB193265473.
Pemetrexed Impurity 12
Pemetrexed Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H29N5O6. Mole Weight: 483.53. Catalog: APB10803.
Pemetrexed Impurity 13
Pemetrexed Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H31N5O6. Mole Weight: 497.55. Catalog: APB10804.
Pemetrexed Impurity 14
Pemetrexed Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 31469-62-2. Molecular Formula: C5H8N4O. Mole Weight: 140.15. Catalog: APB31469622.
Pemetrexed Impurity 15
Pemetrexed Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H14N4O3. Mole Weight: 298.3. Catalog: APB10805.
Pemetrexed Impurity 16
Pemetrexed Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H14N4O3. Mole Weight: 298.3. Catalog: APB10806.
Pemetrexed Impurity 19
Pemetrexed Impurity 19 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C25H28N6O9. Mole weight: 556.52.
Pemetrexed Impurity 25
Pemetrexed Impurity 25 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C8H10N4O4. Mole weight: 226.19.
Pemetrexed Impurity 26
Pemetrexed Impurity 26 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C14H15N5O3. Mole weight: 301.30.
Pemetrexed Impurity 27
Pemetrexed Impurity 27 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C15H15N5O4. Mole weight: 329.31.
Pemetrexed Impurity 28
Pemetrexed Impurity 28 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Impurity 24. Molecular formula: C20H21N5O8. Mole weight: 459.41.
Pemetrexed Impurity 29
Pemetrexed Impurity 29 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41.
Pemetrexed Impurity 3
An impurity of Pemetrexed which binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Grades: > 95%. CAS No. 229470-22-8. Molecular formula: C17H21N5O5. Mole weight: 375.39.
Pemetrexed Impurity 3
Pemetrexed Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123910-88-3. Molecular Formula: C12H16O3. Mole Weight: 208.26. Catalog: APB123910883.
Pemetrexed Impurity 30
Pemetrexed Impurity 30 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C31H40N6O9. Mole weight: 640.68.
Pemetrexed Impurity 30 (4-Methylbenzenesulfonate)
Pemetrexed Impurity 30 (4-Methylbenzenesulfonate). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate 4-methylbenzenesulfonate. CAS No. 165049-28-5. Molecular Formula: C24H29N5O6. Mole Weight: 483.52. Catalog: APB165049285.
Pemetrexed Impurity 31
Pemetrexed Impurity 31 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C27H34N6O6. Mole weight: 538.59.
Pemetrexed Impurity 32
Pemetrexed Impurity 32 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41.
Pemetrexed Impurity 33
Pemetrexed Impurity 33 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. CAS No. 1417656-72-4. Molecular formula: C20H23N5O9. Mole weight: 477.42.
Pemetrexed Impurity 34
Pemetrexed Impurity 34 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H23N5O9. Mole weight: 477.42.
Pemetrexed Impurity 35
Pemetrexed Impurity 35 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H23N5O9. Mole weight: 477.42.
Pemetrexed Impurity 36
Pemetrexed Impurity 36 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41.
Pemetrexed Impurity 37
Pemetrexed Impurity 37 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: 3-(4-carboxyphenyl)-propionaldehyde ethyl ester; 4-(3-oxopropyl)benzoic acid ethyl ester; 4-ethoxycarbonylhydrocinnamal; 3-(4-carbethoxyphenyl)propanal. Grades: ≥ 95%. CAS No. 151864-81-2. Molecular formula: C12H14O3. Mole weight: 206.24.
Pemetrexed Impurity 38
Pemetrexed Impurity 38 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C12H12O4. Mole weight: 220.22.
Pemetrexed Impurity 4
An impurity of Pemetrexed which is a chemotherapy drug. Grades: > 95%. Molecular formula: C15H17N5O5. Mole weight: 347.33.
Pemetrexed Impurity 4
Pemetrexed Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 240407-05-0. Molecular Formula: C12H14O3. Mole Weight: 206.24. Catalog: APB240407050.
Pemetrexed Impurity 42
Pemetrexed Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-diethyl 2-((S)-4-amino-5-ethoxy-5-oxopentanamido)pentanedioate. Molecular Formula: C16H28N2O7. Mole Weight: 360.4. Catalog: APB01399.
Pemetrexed Impurity 5
An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C24H32N6O8. Mole weight: 532.56.
Pemetrexed Impurity 5
Pemetrexed Impurity 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 221558-73-2. Molecular Formula: C12H15NaO6S. Mole Weight: 310.3. Catalog: APB221558732.
Pemetrexed Impurity 50
Pemetrexed Impurity 50. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Pemetrexed Acid Methyl Ester; methyl 4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. CAS No. 155405-80-4. Molecular Formula: C16H16N4O3. Mole Weight: 312.32. Catalog: APB155405804.
Pemetrexed Impurity 51
Pemetrexed Impurity 51. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium 4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. Molecular Formula: C15H13N4O3·Na. Mole Weight: 320.28. Catalog: APB02189.
Pemetrexed Impurity 6
An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C24H30N6O8. Mole weight: 530.54.
Pemetrexed Impurity 6
Pemetrexed Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 155405-79-1. Molecular Formula: C12H13BrO3. Mole Weight: 285.14. Catalog: APB155405791.
Pemetrexed Impurity 7
Pemetrexed Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C28H26N4O5. Mole Weight: 498.54. Catalog: APB10800.
Pemetrexed Impurity 7 (Mixture of Diastereomers)
Pemetrexed Impurity 7 (mixture of diastereomers) is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed 6-oxo diacid impurity; (2S)-2-[[4-[2-(2-amino-4,6-dioxo-5,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid. Grades: ≥ 95%. CAS No. 193281-00-4. Molecular formula: C20H21N5O7. Mole weight: 443.41.
Pemetrexed Impurity 8
Pemetrexed Impurity 8 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Benzoic acid, 4-(3-bromo-4-oxobutyl)-, methyl ester; SCHEMBL1447122; 2-bromo-4-(4-carbomethoxyphenyl)butanal. Grades: > 98%. CAS No. 155405-79-1. Molecular formula: C12H13BrO3. Mole weight: 285.13.
Pemetrexed Impurity 8
Pemetrexed Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S)-2-(4-(2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid. CAS No. 193281-00-4. Molecular Formula: C20H21N5O7. Mole Weight: 443.41. Catalog: APB193281004.
Pemetrexed Impurity 8
Pemetrexed Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1320346-43-7. Molecular Formula: C16H16N4O4. Mole Weight: 328.33. Catalog: APB1320346437.
Pemetrexed Impurity 9
Pemetrexed Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C30H26N8O5. Mole Weight: 578.59. Catalog: APB10802.
Pemetrexed Impurity A
Cas No. 137281-39-1.
Pemetrexed Impurity B
An impurity of Pemetrexed which is a chemotherapy drug. Synonyms: Pemetrexed (5R)-Dimer ; (2S)-2,2'-[[(5R)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82.
Pemetrexed Impurity C
An impurity of Pemetrexed which is a chemotherapy drug used to treat non small cell lung cancer and pleural mesothelioma. Synonyms: Pemetrexed (5S)-Dimer ; (2S)-2,2'-[[(5S)-2,2'-Diamino-4,4',6-trioxo-1,4,4',6,7,7'-hexahydro-1'H,5H-5,6'-bipyrrolo[2,3-d]pyrimidine-5,5'-diyl]bis(ethane-2,1-diylbenzene-4,1-diylcarbonylimino)]-dipentanedioic acid. Grades: > 95%. Molecular formula: C40H40N10O13. Mole weight: 868.82.
Pemetrexed Impurity D
An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. CAS No. 144051-68-3. Molecular formula: C25H28N6O9. Mole weight: 556.54.
Pemetrexed Impurity E Disodium Salt
An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Synonyms: (2R)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid sodium. Grades: >95%. CAS No. 937370-10-0. Molecular formula: C20H19N5Na2O6. Mole weight: 471.38.
Pemetrexed Impurity-R
An impurity of Pemetrexed which belongs to a class of chemotherapeutic drugs known as folate antimetabolites. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42.
Pemetrexed Impurity-S
An impurity of Pemetrexed which is used to treat mesothelioma in combination with another chemotherapy drug called cisplatin. Grades: > 95%. Molecular formula: C20H21N5O7. Mole weight: 443.42.
Pemetrexed acid oxo impurity
An impurity of Pemetrexed which was approved by the United States Food and Drug administration in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug. Synonyms: 4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid. Grades: > 95%. CAS No. 193265-47-3. Molecular formula: C15H14N4O4. Mole weight: 314.3.
Pemetrexed Dimer Impurity 1
Pemetrexed Dimer Impurity 1 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C43H46N10O15. Mole weight: 942.88.
Pemetrexed disodium EP Impurity A
Pemetrexed disodium EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 869791-42-4(free base); (sodium (S)-2-(4-(2-(2-amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate. CAS No. 2243918-27-4. Molecular Formula: C21H21N5Na2O6. Mole Weight: 485.4. Catalog: APB2243918274.
Pemetrexed disodium Impurity 13
Pemetrexed disodium Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid. CAS No. 137281-39-1. Molecular Formula: C15H14N4O3. Mole Weight: 298.3. Catalog: APB137281391.
Pemetrexed disodium Impurity 30
Pemetrexed disodium Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate. Molecular Formula: C24H29N5O6. Mole Weight: 483.52. Catalog: APB01398.
Pemetrexed EP Impurity A
Pemetrexed EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 869791-42-4. Molecular Formula: C21H23N5O6. Mole Weight: 441.44. Catalog: APB869791424.
Pemetrexed EP Impurity B
Pemetrexed EP Impurity B is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (R)-Pemetrexed EP Isomer; (2S, 2'S)-2, 2'- ( (4, 4'- ( ( (R)-2, 2'-Diamino-4, 4', 6-trioxo-4, 4', 5, 6, 7, 7'-hexahydro-1H, 1'H-[5, 6'-bipyrrolo[2, 3-d]pyrimidine]-5, 5'-diyl)bis (ethane-2, 1-diyl))bis (benzoyl))bis (azanediyl))dipentanedioic Acid. Grades: > 98%. CAS No. 1802552-04-0. Molecular formula: C40H40N10O13. Mole weight: 868.80.
Pemetrexed EP Impurity B
Pemetrexed EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1802552-04-0. Molecular Formula: C40H40N10O13. Mole Weight: 868.82. Catalog: APB1802552040.
Pemetrexed EP Impurity C
Pemetrexed EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1802552-16-4. Molecular Formula: C40H40N10O13. Mole Weight: 868.82. Catalog: APB1802552164.
Pemetrexed EP Impurity D
Pemetrexed EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1265908-59-5(Trisodium Salt); (S)-2-((S)-4-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-4-carboxybutanamido)pentanedioic acid. CAS No. 144051-68-3. Molecular Formula: C25H28N6O9. Mole Weight: 556.52. Catalog: APB144051683.
Pemetrexed EP Impurity D Trisodium Salt
Pemetrexed EP Impurity D Trisodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1265908-59-5. Molecular Formula: C25H25N6Na3O9. Mole Weight: 622.48. Catalog: APB1265908595.
Pemetrexed EP Impurity E
Pemetrexed EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid. CAS No. 182009-04-7. Molecular Formula: C20H21N5O6. Mole Weight: 427.41. Catalog: APB182009047.
Pemetrexed EP Impurity E Disodium Salt
Pemetrexed EP Impurity E Disodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 937370-10-0. Molecular Formula: C20H19N5Na2O6. Mole Weight: 471.38. Catalog: APB937370100.
Pemetrexed Monomethyl Ester Impurity 1
An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Synonyms: sodium (4R)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5- yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate. Grades: > 95%. CAS No. 1265908-61-9. Molecular formula: C21H22N5O6.Na. Mole weight: 463.43.
Pemetrexed Monomethyl Ester Impurity 2
An impurity of Pemetrexed which is an antifolate, a substance that blocks the activity of folic acid. Synonyms: Pemetrexed Monomethyl Ester 2; 1265908-60-8; (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-5-methoxy-5-oxopentanoic acid; SCHEMBL15078817; (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid ; Pemetrexed Impurity 2; 1265908-64-2. Grades: > 95%. CAS No. 1265908-60-8. Molecular formula: C21H22N5O6.Na. Mole weight: 463.43.
Pemetrexed ph Euro impurity B + C Mixture (1:1)
Pemetrexed Related Impurity 1
An impurity of Pemetrexed which is used as a single agent or in combination with other chemotherapeutic agents for the treatment of several types of cancer. Grades: > 95%. Molecular formula: C25H28N6O9. Mole weight: 556.54.
Pemetrexed Related Impurity 2
An impurity of Pemetrexed which is an antifolate, a substance that blocks the activity of folic acid. Grades: > 95%. Molecular formula: C20H21N5O8. Mole weight: 459.42.
4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Benzoic acid, 4-[2-(2-amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester; Pemetrexed Impurity 63; Methyl 4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate; Methyl 4-(2-(2-imino-4,6-dioxo-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. Grades: ≥95%. CAS No. 1320346-43-7. Molecular formula: C16H16N4O4. Mole weight: 328.32.
D-Pemetrexed Hydrate
Pemetrexed isomer impurity. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-D-glutamic Acid Hydrate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
N-2-[(Dimethylamino)methylene]amino Pemetrexed
N-2-[(Dimethylamino)methylene]amino pemetrexed is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed N,N-Dimethyl Form Amide Impurity; (4-(2-(2-(((dimethylamino)methylene)amino)-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid. Grades: 98%. CAS No. 1265908-58-4. Molecular formula: C23H26N6O6. Mole weight: 482.49.
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