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Penetratin is a peptide derived from the amphiphilic Drosophila Antennapedia homeodomain [1]. Uses: Scientific research. Group: Peptides. CAS No. 940866-75-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2529.
Penetratin
The first 16 amino acids of Penetratin are derived from the third helix of the Antennapedia protein homeodomain, known as the protein transduction domain (PTD). Penetratin linked to phosphodiester oligonucleotides can penetrate neuronal cell membranes and down-regulate genes. It contains a nuclear localization sequence that facilitates internalization of cargo into living cells. Synonyms: H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Gly-Gly-OH; Pen. Grades: >98%. Molecular formula: C108H174N36O22S. Mole weight: 2360.87.
Penetratin-Arg
Penetratin-Arg, a cell-penetrating peptide (CPP) derived from the 3rd helix of Drosophila Antennapedia homeodomain protein, can permeate cell membrane at low micromolar concentration without significantly affecting membrane. It contains a nuclear localization sequence that facilitates internalization of cargo into living cells. Synonyms: PenArg; H-Arg-Gln-Ile-Arg-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Arg-Trp-Arg-Arg-NH2; L-arginyl-L-glutaminyl-L-isoleucyl-L-arginyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-arginyl-L-tryptophyl-L-arginyl-L-argininamide. Grades: >98%. Molecular formula: C104H169N43O19S. Mole weight: 2357.80.
Antennapedia Peptide
Antennapedia Peptide, a cell-penetrating 16 amino acid peptide originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia, is a member of the family of Cell-penetrating peptides. Synonyms: L-Arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; N5-(diaminomethylidene)-L-ornithyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-N5-(diaminomethylidene)-L-ornithyl-N5-(diaminomethylidene)-L-ornithyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; Penetratin; Penetratin-1; Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys. Grades: ≥98%. CAS No. 188842-14-0. Molecular formula: C104H168N34O20S. Mole weight: 2246.73.
Antennapedia Peptide (43-58), acid
Antennapedia Peptide (43-58), acid, a cell-penetrating peptide corresponding to the region within the DNA binding domain of the Drosophila Antennapedia, is mapped to be responsible for cellular internalization. It is also known as penetratin and has been shown to be able to translocate through the plasma membrane to the cytosol and nucleus of living cells, both at 37°C and 4°C. Synonyms: H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH; L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine. Grades: >95%. Molecular formula: C104H168N34O20S. Mole weight: 2246.76.
Antennapedia Peptide (43-58), amide
Antennapedia Peptide (43-58), amide, a cell-penetrating peptide corresponding to the region within the DNA binding domain of the Drosophila Antennapedia, is mapped to be responsible for cellular internalization. It is also known as penetratin and has been shown to be able to translocate through the plasma membrane to the cytosol and nucleus of living cells, both at 37°C and 4°C. Synonyms: H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2. Grades: >95%. Molecular formula: C104H169N35O19S. Mole weight: 2245.78.
Antennapedia Peptide (43-58), FAM-labeled
Antennapedia Peptide (43-58), FAM-labeled is an antennapedia peptide (Penetratin) labeled with FAM. It is a 16 amino acid peptide corresponding to the region within the Drosophila Antennapedia DNA binding domain that is mapped to be responsible for cellular internalization. It has been shown to be able to translocate through the plasma membrane to the cytosol and nucleus of living cells, both at 37°C and 4°C. Synonyms: 5-FAM-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2. Grades: >95%. Molecular formula: C125H179N35O25S. Mole weight: 2604.08.
Antennapedia Peptide (TFA)
Antennapedia Peptide TFA, a cell-penetrating 16 amino acid peptide originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia, is a member of the family of Cell-penetrating peptide. Synonyms: L-Arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine trifluoroacetic acid; N5-(diaminomethylidene)-L-ornithyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-N5-(diaminomethylidene)-L-ornithyl-N5-(diaminomethylidene)-L-ornithyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine trifluoroacetic acid; Penetratin trifluoroacetic acid; Penetratin-1 trifluoroacetic acid; Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys.TFA. Grades: ≥98%. Molecular formula: C104H168N34O20S.C2HF3O2. Mole weight: 2360.82.
Cys(NPys)-Antennapedia Homeobox (43-58) amide
It is an antennapedia peptide (Penetratin) synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group used for activating S of cysteine and for rapid reaction when a thiol group is introduced. Synonyms: H-Cys(Npys)-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2; Cys(Npys) Antennapedia (43-58) Peptide, amide; Cys(NPys)-Antennapedia Homeobox Protein (43-58) amide (Drosophila melanogaster); Cys(NPys)-Antp Home. Grades: >95%. CAS No. 220337-24-6. Molecular formula: C112H176N38O22S3. Mole weight: 2503.07.
FITC-LC-Antennapedia (43-58) Peptide
It is an antennapedia peptide labeled with fluorescent (FITC). The Antennapedia homeodomain protein of Drosophila has the ability to penetrate biological membranes and the third helix of this protein, residues 43-58, known as penetratin (RQIKIWFQNRRMKWKK-NH2) has the same translocating properties as the entire protein. Synonyms: FITC-LC-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-NH2. Grades: >98%. Molecular formula: C131H189N37O25S2. Mole weight: 2746.31.
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