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Sphingomyelinase (N-SMase) and strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain kinase inhibitor. Also exhibits anti-HIV-1 integrase activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 31186-12-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Nuclease P1 from Penicillium citrinum is a zinc-dependent endonuclease that exhibits increased activity in the presence of low concentrations of urea. Applications: Nuclease p1 from penicillium citrinum has been used in a study to assess crystal structures using ammonium sulphate or polyethylene glycol 4000 as a precipitating agent. it has also been used in a study to investigate a method for the direct sequence analysis 20-25 nucleotides from the terinini of 5? or 3? end group labeled rna. nuclease p1 is used to improve the sensitivity of a 32p-labeling method for the detection of dna adducts. the enzyme has an optimal temperature of approximately 70 oc, but for a long incubation, a temperature below 60 oc is more suitable. it is stable in the ph range of 5-8. Group: Enzymes. Synonyms: Endonuclease P1; EC 3.1.30.1; 54576-84-0; Nuclease P1; P1 nuclease. Enzyme Commission Number: EC 3.1.30.1. CAS No. 54576-84-0. Nuclease. Mole weight: 42-50 kDa. Activity: > 200 units/mg protein (E1%/280, 3?-5?-Phosphodiesterase). Storage: 2-8°C. Form: lyophilized powder. Source: Penicillium citrinum. Endonuclease P1; EC 3.1.30.1; 54576-84-0; Nuclease P1; P1 nuclease. Pack: vial of > 250 units (using RNA substrate). Cat No: NATE-0491.
Native Penicillium janthinellum Carboxypeptidase P
Membrane Pro-Xaa carboxypeptidase (EC 3.4.17.16, carboxypeptidase P, microsomal carboxypeptidase) is an enzyme. This enzyme catalyses the following chemical reaction:Release of a C-terminal residue other than proline, by preferential cleavage of a prolyl bond. This is one of the renal brush border exopeptidases. Applications: Membrane pro-xaa carboxypeptidase (ec 3.4.17.16, carboxypeptidase p, microsomal carboxypeptidase) is an enzyme.[1][2][3] this enzyme catalyses the following chemical reaction release of a c-terminal residue other than proline, by preferential cleavage of a prolyl bond this is one of the renal brush border exopeptidases. Group: Enzymes. Synonyms: Aminoacylproline Carboxypeptidase; CPP; Penicillocarboxypeptidase S-1; Proline Carboxypeptidase; EC 3.4.17.16; Membrane Pro-Xaa carboxypeptidase; carboxypeptidase P; microsomal carboxypeptidase. Enzyme Commission Number: EC 3.4.17.16. CAS No. 9075-64-3. CPP. Storage: -20°C. Form: Lyophilized powder containing sodium Citrate. Source: Penicillium janthinellum. Aminoacylproline Carboxypeptidase; CPP; Penicillocarboxypeptidase S-1; Proline Carboxypeptidase; EC 3.4.17.16; Membrane Pro-Xaa carboxypeptidase; carboxypeptidase P; microsomal carboxypeptidase. Pack: vial of > 100 units. Cat No: NATE-0157.
Native Penicillium sp. α-Rhamnosidase
A thermostable Alpha-L-Rhamnosidase (Naringinase, RhamA) that catalyzes the cleavage of the bond between terminal L (+)-rhamnose and the aglycone of rhamnose-containing glycosides. The enzyme is very active on naringin but has also substantial activity with hesperidin as substrate. Group: Enzymes. Synonyms: glycoside hydrolase; RhamA; naringinase; hesperidinase; α-L-rhamnosidase A; α-L-rhamnosidase N; α-L-rhamnoside rhamnohydrolase; EC 3.2.1.40. Enzyme Commission Number: EC 3.2.1.40. CAS No. 37288-35-0. RhamA. Activity: >0.2 u/mg. Appearance: Tan Powder. Storage: 4°C. Source: Penicillium sp. glycoside hydrolase; RhamA; naringinase; hesperidinase; α-L-rhamnosidase A; α-L-rhamnosidase N; α-L-rhamnoside rhamnohydrolase; EC 3.2.1.40. Cat No: NATE-1164.
Native Penicillium sp. Dextranase
An endodextranase that hydrolyzes-(1,6)-glucosidic linkages in dextran. Dextrans are undesirable compounds synthesized from sucrose by microbial contaminants during sugar production that increase viscosity of the flow and decrease industrial recovery. Dextranase has been used for hydrolyzing dextran at sugar mills in order to improve efficiency of sugar production. Applications: Dextranase from penicillium has been used in a study to assess the purification properties of an extracellular dextranase from penicillium janthinellum. dextranase from penicillium has also been used in a study to investigate the carbohydrate component of penicillium funiculosum dextranase. it has been used for the hydrolysis of carbohydate polymers, during the study of polysaccharide synthesis by phanerochaete chrysosporium. it has also been used in the synthesis of new enzymatically degradable thermo-responsive nanogels. Group: Enzymes. Synonyms: EC 3.2.1.11, dextran hydrolase; endodextranase; dextran. Enzyme Commission Number: EC 3.2.1.11. CAS No. 9025-70-1. Dextranase. Activity: 3,000 units/mg. Storage: 2-8°C. Form: lyophilized powder. Source: Penicillium sp. EC 3.2.1.11, dextran hydrolase; endodextranase; dextranase DL 2; DL 2; endo-dextranase; α-D-1,6-glucan-6-glucanohydrolase; 1,6-α-D-glucan 6-glucanohydrolase; 9025-70-1; Dextranase. Cat No: NATE-0194.
10,11-Dehydrocurvularin
It is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including curvularia, penicillium and alternaria. It inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in alternaria alternata. Synonyms: (4R,8E)-4,5,6,7-Tetrahydro-11,13-dihydroxy-4-methyl-2H-3-benzoxacyclododecin-2,10(1H)-dione; (+)-(10E,15R)-10,11-Dehydrocurvularin; ent-Dehydrocurvularin; (R)-10,11-Dehydrocurvularin; 4,5-[[(7R)-1-Oxo-2-octene-1,7-diyl]oxy(1-oxoethane-1,2-diyl)]benzene-1,3-diol. Grades: >98% by HPLC. CAS No. 1095588-70-7. Molecular formula: C16H18O5. Mole weight: 290.31.
1-Cyclopropane Mycophenolic Acid
1-Cyclopropane Mycophenolic Acid is a non-active analogue of Mycophenolic Acid (M831500), an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides. Group: Biochemicals. Grades: Highly Purified. CAS No. 125198-40-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C18H22O6. US Biological Life Sciences.
Worldwide
1-O-D-Sorbitol Mycophenolate
1-O-D-Sorbitol Mycophenolate is an impurity or sugar conjugate of Mycophenolic Acid (M831500), which is an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. It is a selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C23H32O11, Molecular Weight: 484.49. US Biological Life Sciences.
2,3-O-(1-Methylethylidene)- β-L-erythropentopyranosid-4-ulose Methyl Ether is an intermediate in the synthesis of Neopatulin (N389860), a mycotoxic substance which is produced by Penicillium and Aspergillus species. Group: Biochemicals. Grades: Highly Purified. CAS No. 22596-25-4. Pack Sizes: 100mg, 1g. Molecular Formula: C9H14O5. US Biological Life Sciences.
As an intermediate in the synthesis of Neopatulin, a mycotoxic substance, 2,3-O-(1-Methylethylidene)-β-L-erythropentopyranosid-4-ulose Methyl Ether is produced by Penicillium and Aspergillus species. Synonyms: 4H-1,3-Dioxolo[4,5-c]pyran, β-L-erythro-pentopyranosid-4-ulose Deriv; β-2,3-O-Isopropylidene-L-erythro-pentopyranosid-4-ulose. CAS No. 22596-25-4. Molecular formula: C9H14O5. Mole weight: 202.2.
2-(Demethoxy)ethylthio-griseofulvin
2-(Demethoxy)ethylthio-griseofulvin is an intermediate in the synthesis of Griseofulvin-d3, the labeled analogue of Griseofulvin (G787500), an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum. Group: Biochemicals. Grades: Highly Purified. CAS No. 187884-75-9. Pack Sizes: 25mg, 250mg. Molecular Formula: C18H19ClO5S, Molecular Weight: 382.86. US Biological Life Sciences.
Worldwide
3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol. (Mixture of Diastereomers)
3-[1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy]-1,2-propanediol is involved in biological studies as microsomal cytochrome P 450 isoenzymes from Penicillium italicum interaction with sterol demethylation inhibitor fungicides. Group: Biochemicals. Grades: Highly Purified. CAS No. 86491-83-0. Pack Sizes: 50mg, 500mg. Molecular Formula: C14H16Cl2N2O3. US Biological Life Sciences.
Worldwide
3beta-Acetoxyfern-9(11)-en-19beta-ol
It is produced by the strain of Penicillium berteriana. Synonyms: 3beta-Acetoxyferna-9(11)-Ene-19beta-ol; (1S, 3R, 3aR, 5aR, 5bR, 7aR, 9S, 11aS, 13aS, 13bR)-1-hydroxy-3-isopropyl-3a, 5a, 8, 8, 11a, 13a-hexamethyl-2, 3, 3a, 4, 5, 5a, 5b, 6, 7, 7a, 8, 9, 10, 11, 11a, 13, 13a, 13b-octadecahydro-1H-cyclopenta[a]chrysen-9-yl acetate; 3β-Acetoxyfern-9(11)-en-19β-ol. Molecular formula: C32H52O3. Mole weight: 484.75.
44-HomooIigomycin A
44-HomooIigomycin A is an antitumor antibiotic produced by Streptomyces bottropensis. It has activity against fungi such as Aspergillus, Penicillium and Fusarium, but not against yeast and bacteria. It has moderate anti-tumor activity against Colon 26 in vivo. Synonyms: 26-Demethyl-26-ethyloligomycin; NK86-0279 II. CAS No. 132707-68-7. Molecular formula: C46H76O11. Mole weight: 805.09.
44-HomooIigomycin B
44-HomooIigomycin B is an antitumor antibiotic produced by Streptomyces bottropensis. It has activity against fungi such as Aspergillus, Penicillium and Fusarium, but not against yeast and bacteria. It has moderate anti-tumor activity against Colon 26 in vivo. Synonyms: 26-Demethyl-26-ethyl-28-oxooligomycin A; NK86-0279 I. CAS No. 125616-18-4. Molecular formula: C46H74O12. Mole weight: 819.07.
4,6-Dimethoxy-2'-methyl-3,4',6'-grisantrione
Metabolic product of Penicillium patulum. Group: Biochemicals. Alternative Names: 4,6-Dimethoxy-6'-methyl-spiro[benzofuran-2(3H),1'-cyclohexane]-2',3,4'-trione. Grades: Highly Purified. CAS No. 2855-92-7. Pack Sizes: 10mg. US Biological Life Sciences.
6,11-Di-O-acetylalbrassitriol is produced from the fungus Penicillium sp. Synonyms: 1,4-Naphthalenediol, 1-[(acetyloxy)methyl]-1,4,4a,5,6,7,8,8a-octahydro-2,5,5,8a-tetramethyl-, 4-acetate, [1R-(1α, 4α, 4aα, 8aβ)]-. Grades: 98.0%. CAS No. 110538-20-0. Molecular formula: C19H30O5. Mole weight: 338.44.
6',7'-Epoxybergamottin
6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Epoxybergamottin. CAS No. 206978-14-5. Pack Sizes: 1 mg. Product ID: HY-126983.
(+)-6-Aminopenicillanic Acid
(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins. Group: Biochemicals. Alternative Names: (2S, 5R, 6R)-6-Amino-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid; 6-APA; 6-APS; 6 β-Aminopenicillanic acid; NSC 50071; [2S-(2α,5α,6 β )]-6-Amino-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid; Phenacyl 6-Aminopenicillinate. Grades: Highly Purified. CAS No. 551-16-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
7-Hydroxypestalotin
A minor analogue metabolite of pestalotin isolated from penicillium decumbens. It is phytotoxic against evening primrose, prickly sida, johnsongrass, morning glory, lambsquarter and A. abla. Synonyms: 6,7-Dihydroxy-3-methoxy-2-decen-5-olide; LL-P880 beta; (6S)-6-[(1S,2R)-1,2-Dihydroxypentyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one; (6S,1'S,2'R)-LL-P880β; LL-P880&beta. Grades: >99% by HPLC. CAS No. 41164-59-4. Molecular formula: C11H18O5. Mole weight: 230.26.
9-Demethyl FR-901235
9-demethyl FR-901235 is a polyketide fungal metabolite produced by the strain of Penicillium. Synonyms: FR-901235, 9-Demethyl; (+)-2,4,6,9-tetrahydroxy-7-methyl-2-(2-oxopropyl)-1H-phenalene-1,3(2H)-dione. Grades: >95% by HPLC. CAS No. 1029520-85-1. Molecular formula: C17H14O7. Mole weight: 330.29.
9-Hydroxyoudemansin A
9-Hydroxyoudemansin A is an antibiotic produced by Mycena sp. HKI 0153. It has antifungal activity, lower than Oudemansin (Oudemansin), has an MIC of 12.5 μg/mL against ochre-like yeast, and is resistant to fungi such as Candida albicans, Crimson Yeast, Penicillium and Streptomyces with MICs are all> 50 μg/mL. No anti-bacterial effect. Synonyms: Noroudemansin A; 9-De-O-methyloudemansin A. CAS No. 225937-85-9. Molecular formula: C16H20O4. Mole weight: 276.33.
α-1-O-Methyl-4-deoxy-4-(carboxyethylmethylene) D-Lyxose is an intermediate in the synthesis of Neopatulin, a mycotoxic substance which is produced by Penicillium and Aspergillus species. Molecular formula: C10H16O6. Mole weight: 232.23.
aristolochene synthase
The initial internal cyclization produces the monocyclic intermediate germacrene A; further cyclization and methyl transfer converts the intermediate into aristolochene. While in some species germacrene A remains as an enzyme-bound intermediate, it has been shown to be a minor product of the reaction in Penicillium roqueforti (see also EC 4.2.3.23, germacrene-A synthase). The enzyme from Penicillium roqueforti requires Mg2+. Mn2+ can partially substitute, at low concentrations. Aristolochene is the likely parent compound for a number of sesquiterpenes produced by filamentous fungi. Group: Enzymes. Synonyms: sesquiterpene cyclase; trans,trans-farnesyl diphosphate aristolochene-lyase; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Enzyme Commission Number: EC 4.2.3.9. CAS No. 94185-89-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5253; aristolochene synthase; EC 4.2.3.9; 94185-89-4; sesquiterpene cyclase; trans,trans-farnesyl diphosphate aristolochene-lyase; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming). Cat No: EXWM-5253.
Asterric Acid (Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A)
A fungal metabolite, asterric acid is isolated from a number of Aspergillus and Penicillium species. It is an inhibitor of vascular endothelial growth factor (VEGF). Asterric acid is an angiogenesis inhibitor acting on VEGF-induced tube formation of human umbilical vein endothelial cells. Group: Biochemicals. Alternative Names: Dimethylosoic acid, Antibiotic TAN 1415A, Antibiotic WF 12880A. Grades: Highly Purified. CAS No. 577-64-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Atpenin A5
Atpenin A5 is an inhibitor of SDHB, SDHC and SDHD. It is an antifungal antibiotic produced by Penicillium sp. and an ubiquinone-binding site inhibitor of succinate dehydrogenase with IC50s of 12 nM for nematode and IC50s of 3.7 nM for mammalian mitochondria. Atpenin A5 is the most effective inhibitor against complex II from all the atpenins and has been shown to protect against cardiac-reperfusion injury in rat studies through the stimulation of mitochondrial KATP channels. Synonyms: Antibiotic FO-125A5. Grades: ≥95%. CAS No. 119509-24-9. Molecular formula: C15H21Cl2NO5. Mole weight: 366.2.
Synthetic. Originally isolated from Penicillium sp. strain. An antibiotic and antifungal agent. Potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor and mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator. Modulates mitochondrial ROS generation during cardioprotection. Group: Biochemicals. Grades: Highly Purified. CAS No. 119509-24-9. Pack Sizes: 250ug, 1mg. US Biological Life Sciences.
Worldwide
Benzomalvin A
It is produced by the strain of Penicillum sp. Benzomalvin A was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin A is a fungal metabolite produced by Penicillium. It inhibits yeast α-glucosidase in vitro with IC50 of 383.2 μM. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P to guinea pig, rat, and human NK1 (Kis = 12, 42, and 43 μM, respectively). Synonyms: (-)-Benzomalvin A; Enzomalvin-A. Grades: ≥95%. CAS No. 157047-96-6. Molecular formula: C24H19N3O2. Mole weight: 381.43.
Benzomalvin B
It is produced by the strain of Penicillum sp. Benzomalvin B was isolated as an active inhibitor of substance P binding to mammalian neurokinin NK1 receptors. Benzomalvin B is a fungal metabolite produced by Penicillium. It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P by 24% in vitro when used at a concentration of 100 μg/ml. Synonyms: (-)-Benzomalvin B; Enzomalvin-B. Grades: ≥95%. CAS No. 157047-97-7. Molecular formula: C24H17N3O2. Mole weight: 379.41.
Bilaid A
Bilaid A is a tetrapeptide agonist of the μ-opioid receptor originally isolated from Penicillium. It inhibits forskolin-induced cAMP accumulation in HEK293 cells expressing the human μ-opioid receptor by 21% when used at a concentration of 10 μM. Synonyms: L-Phenylalanyl-D-valyl-L-valyl-D-phenylalanine. Grades: ≥95%. CAS No. 2393865-97-7. Molecular formula: C28H38N4O5. Mole weight: 510.62.
Bilaid B
Bilaid B is a tetrapeptide originally isolated from Penicillium. Synonyms: L-Phenylalanyl-D-valyl-L-valyl-D-tyrosine; H-FVVY-OH; H-L-Phe-D-Val-L-Val-D-Tyr-OH. Grades: ≥95%. CAS No. 2393866-06-1. Molecular formula: C28H38N4O6. Mole weight: 526.62.
Bilaid B1
Bilaid B1 is a tetrapeptide and derivative of bilaid B which is originally isolated from Penicillium. Synonyms: L-phenylalanyl-D-valyl-L-valyl-D-tyrosinamide; H-FVVY-NH2; H-L-Phe-D-Val-L-Val-D-Tyr-NH2. Grades: >95% by HPLC. CAS No. 2393866-07-2. Molecular formula: C28H39N5O5. Mole weight: 525.64.
Bilaid C
Bilaid C is a tetrapeptide μ-opioid receptor agonist originally isolated from Penicillium. It inhibits forskolin-induced cAMP accumulation by 77% in HEK293 cells expressing the human μ-opioid receptor when used at a concentration of 10 μM. Bilaid C also induces inward rectifying potassium channel (Kir) currents in rat locus coeruleus slices that endogenously express high levels of the μ-opioid receptor (EC50 = 4.2 μM). Synonyms: L-Tyrosyl-D-valyl-L-valyl-D-phenylalanine; H-L-Tyr-D-Val-L-Val-D-Phe; H-YVVF. Grades: >95% by HPLC. CAS No. 2393866-13-0. Molecular formula: C28H38N4O6. Mole weight: 526.62.
Brevicompanine B
A diketopiperazine-related metabolite produced by penicillium brevicompactum and aspergillus species. It has obvious plant growth regulation activity, but is devoid of antifungal or antimicrobial activity. It is active against Plasmodium falciparum. Synonyms: (3R,5aS,10bR,11aS)-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grades: >99% by HPLC. CAS No. 215121-47-4. Molecular formula: C22H29N3O2. Mole weight: 367.48.
Brevicompanine B
Brevicompanine B is a diketopiperazine related metabolite produced by Penicillium and Aspergillus species. Brevicompanine B was found to be active against the malaria parasite Plasmodium falciparum and has been demonstrated to show pronounced plant growth regulatory activity but is devoid of antifungal or antibacterial activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 215121-47-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Bromonitrin A
Bromonitrin A is an antibiotic produced by Pseudomonas pyrrolnimica in a bromide-containing medium. It has anti-Gram-positive bacteria, Penicillium chrysogenum, Trichophyton interdigita and Candida albicans. CAS No. 23305-90-0. Molecular formula: C10H6Br2N2O2. Mole weight: 345.97.
Bromonitrin B
Bromonitrin B is an antibiotic produced by Pseudomonas pyrrolnimica in a bromide-containing medium. It has anti-Gram-positive bacteria, Penicillium chrysogenum, Trichophyton interdigita and Candida albicans. CAS No. 23305-91-1. Molecular formula: C10H5Br3N2O2. Mole weight: 424.87.
Bromonitrin C
Bromonitrin C is an antibiotic produced by Pseudomonas pyrrolnimica in a bromide-containing medium. It has anti-Gram-positive bacteria, Penicillium chrysogenum, Trichophyton interdigita and Candida albicans. Synonyms: 2,3-dibromo-4-(5-bromo-2-nitrophenyl)-1H-pyrrole;BromonitrinC;32736-23-5. Grades: 95%. CAS No. 32736-23-5. Molecular formula: C10H5Br3N2O2. Mole weight: 424.87.
Canadensolide
Canadensolide is a bislactone antibiotic isolated from Penicillium canadense, Aspergillus flavus and A. tamarii. It shows antifungal activity. Synonyms: (-)-Canadensolide; Furo(3,4-b)furan-2,4-dione, 6-butyltetrahydro-3-methylene-, (3aS,6R,6aR)-; (3aS,6R,6aR)-6-Butyl-3-methylenetetrahydrofuro[3,4-b]furan-2,4-dione. CAS No. 20421-31-2. Molecular formula: C11H14O4. Mole weight: 210.23.
Carneamide A
Carneamide A is an indoloterpene alkaloid and a metabolite of Penicillium molds produced by Aspergillus fungi. CAS No. 1392300-52-5. Molecular formula: C27H31N3O3. Mole weight: 445.55.
Carneamide B
Carneamide B is an indoloterpene alkaloid and a metabolite of Penicillium molds produced by Aspergillus fungi. CAS No. 1392300-53-6. Molecular formula: C27H29N3O3. Mole weight: 443.54.
Carriomycin
It is produced by the strain of Streptomyces hygroscoppicus T-42082. It has activities against gram-positive bacteria, mycoplasma, yeast and pipeospora rice and other fungi and coccidia, but has no effect on gram-negative bacteria, aspergillus, penicillium and other fungi. CAS No. 65978-43-0. Molecular formula: C47H80O15. Mole weight: 885.13.
catalase
A hemoprotein. A manganese protein containing MnIII in the resting state, which also belongs here, is often called pseudocatalase. The enzymes from some organisms, such as Penicillium simplicissimum, can also act as a peroxidase (EC 1.11.1.7) for which several organic substances, especially ethanol, can act as a hydrogen donor. Enzymes that exhibit both catalase and peroxidase activity belong under EC 1.11.1.21, catalase-peroxidase. Group: Enzymes. Synonyms: equilase; caperase; optidase; catalase-peroxidase; CAT. Enzyme Commission Number: EC 1.11.1.6. CAS No. 9001-5-2. CAT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0508; catalase; EC 1.11.1.6; 9001-05-2; equilase; caperase; optidase; catalase-peroxidase; CAT. Cat No: EXWM-0508.
Chaetoglobosin A
Chaetoglobosin A, the active principle within the extract of Penicillium aquamarinium , is a member of the cytochalasan family. Chaetoglobosin A preferentially induces apoptosis. Chaetoglobosin A targets filamentous actin in CLL cells and thereby induces cell-cycle arrest and inhibits membrane ruffling and cell migration [1]. Uses: Scientific research. Group: Natural products. CAS No. 50335-03-0. Pack Sizes: 1 mg. Product ID: HY-N6744.
Citreomontanin
A metabolite of penicillium pedemontanum. Synonyms: all-E-citreomontanin; Citreomontanine; 2H-Pyran-2-one, 4-methoxy-5-methyl-6-(7,9,11-trimethyl-1,3,5,7,9,11-tridecahexaenyl)-, (all-E)-; 4-methoxy-5-methyl-6-((1E,3E,5E,7E,9E,11E)-7,9,11-trimethyltrideca-1,3,5,7,9,11-hexaen-1-yl)-2H-pyran-2-one. Grades: 95%. CAS No. 74474-66-1. Molecular formula: C23H28O3. Mole weight: 352.47.
Citreoviridin
Citreoviridin is the dominant analogue of a family a tetraene mycotoxins with potent neurotoxic effects, produced by several species of the genera Aspergillus and Penicillium. Citreoviridins act as inhibitors of mitochondrial ATPase and are a causative agent of cardiac beriberi. Group: Biochemicals. Grades: Highly Purified. CAS No. 25425-12-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Citreoviridin
The dominant analogue of a family of tetraene mycotoxins with potent neurotoxic effects, produced by several species of aspergillus and penicillium. It inhibits mitochondrial ATPase and is a causative agent of cardiac beriberi. Synonyms: Citreoviridin A; Citreoviridine; Citreoviridine A; [2S-[2α(1E, 3E, 5E, 7E), 3β, 4α, 5α]]-4-Methoxy-5-methyl-6-[7-methyl-8-(tetrahydro-3, 4-dihydroxy-2, 4, 5-trimethyl-2-furanyl)-1, 3, 5, 7-octatetraenyl]-2H-pyran-2-one; 2,5-Anhydro-1,6-dideoxy-2-C-[(1E,3E,5E,7E)-8-(4-methoxy-5-methyl-2-oxo-2H-pyran-6-yl)-2-methyl-1,3,5,7-octatetraenyl]-4-C-methyl-D-Iditol. Grades: >97% by HPLC. CAS No. 25425-12-1. Molecular formula: C23H30O6. Mole weight: 402.48.
Citrinin
Citrinin is a quinonemethine mycotoxin produced by diverse fungal genera, including Aspergillus and Penicillium. Citrinin has been extensively investigated. It is a potent nephrotoxin with hepatoxic and teratogenic activity. It is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption to a wide variety of mitochrondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 518-75-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(-)-Citrinin
Antibiotic substance produced by a white spore aspergilus which has been placed under the species name Aspergillus niveus. Also produced in small quantities by Penicillium citrinum. Group: Biochemicals. Alternative Names: (3R,4S)-4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic Acid. Grades: Highly Purified. CAS No. 518-75-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. US Biological Life Sciences.
Worldwide
Citromycetin
Citromycetin is an aromatic polyketide compound from Australian marine-derived and terrestrial Penicillium spp. Group: Heterocyclic organic compound. Alternative Names: Frequentic acid. CAS No. 478-60-4. Molecular formula: C14H10O7. Mole weight: 290.22. Appearance: Yellow solid. Purity: 95%+. IUPACName: 8,9-Dihydroxy-2-methyl-4-oxo-5H-pyrano[3,2-c]chromene-10-carboxylic acid. Canonical SMILES: CC1=CC (=O)C2=C (O1)C3=C (C=C (C (=C3C (=O)O)O)O)OC2. Catalog: ACM478604.
Cyclochlorotine
It is produced by the strain of Penicillium islandicum. It can accelerate the degradation of glycogen and make the Liver glycogen particles disappear. Synonyms: Chloropeptide; Cyclic(L-3-phenyl-beta-alanyl-L-seryl-(3S-cis)-3,4-dichloro-L-prolyl-L-alpha-aminobutyryl-L-seryl). Grades: ≥ 98%. CAS No. 12663-46-6. Molecular formula: C24H31Cl2N5O7. Mole weight: 572.44.
Cyclo(L-Leu-L-Trp)
Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria and fungi, and it also inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 μM). Synonyms: 3S-(1H-indol-3-ylmethyl)-6S-(2-methylpropyl)-2,5-piperazinedione; Cyclo(L-leucyl-L-tryptophyl); Cyclo(leu-trp); Cyclo(L-Trp-L-Leu); 2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(2-methylpropyl)-, (3S-cis)-. Grades: ≥95%. CAS No. 15136-34-2. Molecular formula: C17H21N3O2. Mole weight: 299.37.
(±)-Cyclopenin
(±)-Cyclopenin is produced by a benzodiazepine metabolite produced by Penicillium. It is almost non-toxic to mammalian cells, bacteria or fungi in vitro. Synonyms: Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'R)-rel-. Grades: >99% by HPLC. CAS No. 19553-26-5. Molecular formula: C17H14N2O3. Mole weight: 294.30.
Cyclopeptine
A benzodiazepine metabolite produced by a number of species of penicillium. Synonyms: (S)-cyclopeptine; (3S)-3-benzyl-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione. Grades: >99% by HPLC. CAS No. 50886-63-0. Molecular formula: C17H16N2O2. Mole weight: 280.32.
Cyclopeptine is a benzodiazepine metabolite produced by a number of species of Penicillium. While there is little literature about the metabolite there is considerable interest in the enzymes responsible for the biosynthesis of the benzodiazepine nucelus, cyclopeptine synthetase. Group: Biochemicals. Alternative Names: Benzyl-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione. Grades: Highly Purified. CAS No. 50886-63-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
cyclopeptine synthase
Cyclopeptine synthase is the key enzyme of benzodiazepine alkaloid biosynthesis in the fungus Penicillium cyclopium. The enzyme is a non-ribosomal peptide synthase. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5758; cyclopeptine synthase; EC 6.3.2.40. Cat No: EXWM-5758.
Cyclopiazonic acid
It is produced by the strain of Various penicillium. It's a mycotoxin and it's neurotoxic. Its toxicity is linked to its ability to specifically and reversibly inhibit sarco-endoplasmic reticulum Ca2+-ATPases. Synonyms: (6aR,11aS,11bR)-10-Acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one. Grades: 98% (HPLC). CAS No. 18172-33-3. Molecular formula: C20H20N2O3. Mole weight: 336.39.
Cyclopiazonic Acid
Cyclopiazonic acid is a tremorigenic indole produced by several species of the genera Aspergillus and Penicillium. Cyclopiazonic acid is a highly specific inhibitor of calcium ATPase of sarcoplasmic reticulum, altering calcium homeostasis and ATP-dependent calcium transport and resulting in the induction of release of intracellular stored Ca2+ without increasing IP3. Group: Biochemicals. Grades: Highly Purified. CAS No. 18172-33-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin C
Cyclosporin C is a fungal metabolite that has been found in T. inflatum and has diverse biological activities, including antifungal , antiviral, and immunosuppressant properties. Cyclosporin C is active against isolates of B. cinerea , A. niger , and Alternaria , Mucor , and Penicillium species (MICs=0.1-5 μg/ml). Uses: Scientific research. Group: Signaling pathways. CAS No. 59787-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6027.
Cyclothiocurvularin A
Cycuriocurvularin is a 12-membered macrolide isolated from Penicillium and Curvularia sp. Grades: >95% by HPLC. Molecular formula: C19H22O8S. Mole weight: 410.44.
Dehydrocyclopeptine
A benzodiazepine metabolite produced by many species of penicillium. Synonyms: (Z)-dehydrocyclopeptine; 3,10-Dehydrocyclopeptine; (Z)-3,10-dehydrocyclopeptine. Grades: >99% by HPLC. CAS No. 31965-37-4. Molecular formula: C17H14N2O2. Mole weight: 278.31.
Dehydrocyclopeptine
Dehydrocyclopeptine is a benzodiazepine metabolite produced by a number of species of Penicillium. While there is little literature about the metabolite there is considerable interest in the enzymes responsible for the biosynthesis of the benzodiazepine nucelus, cyclopeptine synthetase. Group: Biochemicals. Grades: Highly Purified. CAS No. 31965-37-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Deoxybrevianamide E
An alkaloidal diketopiperazine derived from tryptophan and proline, isolated from aspergillus and penicillium species. Synonyms: L-Prolyl-2-(1,1-dimethylallyl)-L-tryptophan anhydride; (3S,8aS)-3-[[2-(1,1-Dimethyl-2-propen-1-yl)-1H-indol-3-yl]methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Prolyl-2- (1, 1-dimethylallyl) tryptophyldiketopiperazine; (3S-trans)-3-[[2-(1,1-Dimethyl-2-propenyl)-1H-indol-3-yl]methyl]hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione; Desoxybrevianamide E; cyclo-2-(1,1-dimethylallyl)-L-tryptophyl-L-proline; cyclo-L-prolyl-2-(1,1-dimethylallyl)-L-tryptophan. Grades: >99% by HPLC. CAS No. 34610-68-9. Molecular formula: C21H25N3O2. Mole weight: 351.44.
Deoxybrevianamide E (L-Prolyl-2-(1,1-dimethylallyl)-L-tryptophan Anhydride)
Deoxybrevianamide E is an alkaloidal diketopiperazine derived from tryptophan and proline, isolated from Aspergillus and Penicillium species. There are no reports of intensive investigation of deoxybrevianamide E. In-house screening identified weak activity against mammalian tumor cells but no antibacterial or antifungal activity. Group: Biochemicals. Alternative Names: L-Prolyl-2-(1,1-dimethylallyl)-L-tryptophan Anhydride. Grades: Highly Purified. CAS No. 34610-68-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl-6-hydroxy-deoxyfunicone
Desmethyl-6-hydroxy-deoxyfunicone is a derivative of Funicone, which is a new metabolite from a strain of Penicillium funiculosum Thom. Molecular formula: C18H16O8. Mole weight: 360.31.
deuterolysin
Proteolytic activity found in Penicillium roqueforti, P. caseicolum, Aspergillus sojae and A. oryzae. Optimum pH of 5 for digesting various proteins. Strong action on protamine and histones. Insensitive to phosphoramidon. About 20 kDa. A distinct Aspergillus sojae endopeptidase is larger and has a neutral pH optimum. Type example of peptidase family M35. Formerly included in EC 3.4.24.4. Group: Enzymes. Synonyms: Penicillium roqueforti protease II; microbial neutral proteinase II; acid metalloproteinase; neutral proteinase II; Penicillium roqueforti metalloproteinase. Enzyme Commission Number: EC 3.4.24.39. CAS No. 247028-11-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4321; deuterolysin; EC 3.4.24.39; 247028-11-1; Penicillium roqueforti protease II; microbial neutral proteinase II; acid metalloproteinase; neutral proteinase II; Penicillium roqueforti metalloproteinase. Cat No: EXWM-4321.
DEXTRANASE
DEXTRANASE. Synonyms: dextranase from paecilomyces lilacinus;Dextranase Paecilomyces lilacinus;dextranase partially purified. CAS No. 9025-70-1. Product ID: CDF4-0042. Category: Enzyme Preparations. Product Keywords: Food Ingredients; Enzyme Preparations; DEXTRANASE; CDF4-0042; 9025-70-1; 232-803-9; 9025-70-1. Purity: 0.99. Color: Brown. EC Number: 232-803-9. Physical State: Solution. Storage: 2-8°C. Product Description: Dextranase from fungi belong to the glycoside hydrolase families (GH) 49. Dextranase from Penicillium sp. are stable at varying temperature and pH.
Dimethoxy Analogue of Mycophenolic Acid
An impurity of Mycophenolic Acid which is derived from various Penicillium fungal species. Grades: > 95%. Molecular formula: C18H22O6. Mole weight: 334.37.
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