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AY-NH is a selective proteinase-activated receptor 4 (PAR4) receptor agonist peptide. It stimulates aggregation of rat and human platelets in vitro. It reduces expression of glycoprotein (GP) Ib, and increases expression of GPIIb/IIIa on the surface of human platelets. It induces relaxation of isolated rat aortic rings and contraction of rat gastric longitudinal muscle strips. It also inhibits calcium mobilization evoked by capsaicin in rat sensory neurons. It increases paw thickness in a rat paw edema inflammation model in vivo. Synonyms: PAR-4 Agonist Peptide, amide; L-Alanyl-L-tyrosyl-L-prolylglycyl-L-lysyl-L-phenylalaninamide; PAR-4-AP; Proteinase-activated Receptor 4 Activating Peptide. Grades: 98%. CAS No. 352017-71-1. Molecular formula: C34H48N8O7. Mole weight: 680.79.
BRL-37344 sodium
BRL37344 is a selective β3-adrenergic receptor agonist originated by GlaxoSmithKline. Ki value is 287nM for β3 receptor, 1750nM for β1 receptor and 1120nM for β2 receptor. BRL37344 can decrease nerve-evoked contractions in human detrusor smooth muscle isolated strips, it can also stimulate fuel oxidation by soleus muscle in vitro. BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin. But preclinical for Diabetes mellitus was discontinued. Uses: Diabetes mellitus. Synonyms: BRL-37344 sodium; BRL 37344 sodium; BRL37344 sodium; sodium; 2- [4- [ (2R) -2- [ [ (2R) -2- (3-chlorophenyl) -2-hydroxyethyl] amino] propyl] phenoxy] acetate. Grades: 98 %. CAS No. 127299-93-8. Molecular formula: C19H21ClNNaO4. Mole weight: 385.82.
HA-1004
HA-1004 is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein, and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 is an antagonist for calcium , that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 91742-10-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-123468.
HA1077 (Fasudil Dihydrochloride)
A potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced contraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho-associated Kinase (ROCK).HA1077 is an inhibitor of ROK/ROCK II (IC50 1.9uM), PRK2 (IC50 4uM), MSK1 (IC50 5uM), Rsk2 (IC50 15uM), PKA, p70 S6 Kinase, CaM Kinase (Ki 1.8nM) and MLCK (Ki 20nM). HA1077 is a calcium antagonist and has antivasospastic properties. Inhibits ROKa/ROCK II, PRK2, MSK1, Rsk2, PKA, p70 S6 Kinase, CaM Kinase and MLCK. Group: Biochemicals. Alternative Names: Fasudil Dihydrochloride; 1-(5-Isoquinolinesulfonyl)-1H-hexahydro-1,4-diazepine 2HCl; 1-(5-Isoquinolinesulfonyl) homopiperazine 2HCl). Grades: Highly Purified. CAS No. 103745-39-7. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C14H17N3O2S 2HCl, Molecular Weight: 364.29. US Biological Life Sciences.
Worldwide
NS 11021
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels. It has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro. Synonyms: NS-11021; NS 11021; NS11021. N'-[3,5-Bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl-phenyl]thiourea. Grades: ≥98% by HPLC. CAS No. 956014-19-0. Molecular formula: C16H9BrF6N6S. Mole weight: 511.24.
2,6-Dimethyl-4-heptanone
Diisobutyl ketone is used as a solvent fornitrocellulose, lacquers, and synthetic resins;in organic syntheses.;Uses Diisobutyl ketone (DIBK) is a transparent liquid with a distinct odor and a high boiling point. It is an heavy-end byproduct of producing MIBK. DIBK is used in many applications such as nitrocellulose lacquers, synthetic resins, coatings and stains, paint strippers, leather finishings, adhesives, printing and coating inks, cleaning and dregreasing, Flavors and fragrances, solvent and re-crystallization aid for pharmaceuticals, mining, and as a chemical intermediate. DIBK has good activity for many synthetic resins including nitrocellulose, rosin esters, phenolics, hydrocarbons, alkyds, polyesters, and acrylics. It is useful as a retarder solvent to improve flow and minimize humidity blushing. The low density and low surface tension of DIBK enables formulators to develop high-solids coatings with low VOC content and excellent flow and leveling properties. DIBK has excellent viscosity reduction for and reduces surface tension in high solids coatings. It has good volume-to-weight advantage over other classes of solvents used in coatings. Alternative Names: isovaleron; METHYL NONYL KETONE, 2-HENDECANONE; 2,6-dimethylheptan-4-one; DIISOBUTYL KETONE (DIBK): CP; 2,6-Dimethylheptan-4-one; DIISOBUTYL KETONE FOR SYNTHESIS; DIISOBUTYLKETONE; ISOBUTYL KETONE; FEMA 3537; DIBK; Diisobutyl Ketone; 2,6-Dimethyl-4-HÂ…
5'-O-Tritylthymidine 3'-CE phosphoramidite
5'-O-Tritylthymidine 3'-CE phosphoramidite, a versatile and indispensable reagent wielded in oligonucleotide synthesis techniques, earns its stripes adding a 3'-phosphate group. Favored in academia for biomedicine research as well as the flourishing therapeutics industry, it has paved the way towards treating an array of ailments from genetic disorders to viral infections to cancer. CAS No. 198637-50-2. Molecular formula: C38H45N4O6P. Mole weight: 684.78.
7-Dodecyn-1-ol
7-Dodecyn-1-ol is the precursor for the sex pheromones, (E) and (Z)-7-Dodecenyl acetate, of Spodoptera frugiperda (Fall armyworm), Spodoptera praefica (Western yellow-striped armyworm), Thysanoplusia orichalcea (Golden wing moth), Agrotis segetum (Turnip moth) and Loxagrotis albicosta (Western bean cutworm). Group: Heterocyclic organic compound. Alternative Names: 7-Dodecynol - Dodec-7-yn-1-ol - 7-Dodecyne-1-ol - 1-Butyl-2-(6-hydroxyhexyl)acetylene. CAS No. 41862-94-6. Molecular formula: C12H22O. Mole weight: 182.31. Appearance: Clear, colourless to pale yellow liquid. Purity: 95.0% minimum. Catalog: ACM41862946.
Calcium Hydroxide
Calcium Hydroxide, also known as Hydrated Lime or Slaked Lime, finds utility across diverse industrial sectors, serving purposes including water treatment, anti-stripping agent, acid neutralization, buffering, and soil stabilization. Uses: Acid Neutralizer, Buffer, pH Control, Water Treatment. Alternative Names: Hydrated Lime, Lime, Lime Slaked, Slaked Lime, Rotary Calcium Hydroxide. CAS No. 1305-62-0. Pack Sizes: 50lb.
USA
Cefonicid sodium
Cefonicid sodium is a broadspectrum cephalosporin antibiotic which can be detected using adsorptive square-wave stripping voltammetry. Uses: A semisynthetic second-generation broadspectrum cephalosporin with antibacterial activity that inhibits the formation of the bacterial cell wall. Synonyms: disodium;(6S,7S)-7-[[(2S)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[1-(sulfonatomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate. Grades: ≥95%. CAS No. 61270-78-8. Molecular formula: C18H16N6Na2O8S3. Mole weight: 586.53.
Magnolia Extract (Standard)
Magnolia bark is a highly aromatic herbal material obtained from Magnolia officnalis L. of the family Magnoliaceae. The pharmacy item is obtained by stripping the bark from stems, branches and roots. The Chinese name for the herb, houpu, refers to the thick (hou) bark that is the unadorned (pu) portion of the plant. Applications: It can protect the brain from alzheimer's disease.as strong antioxidants, it can do well to cardiovascular health.it has the function to inhibit the growth of cancer tumors.it can help calm nerves and alleviate anxiety without side effect.it can inhibit bacteria and pathogenic fungi. Group: Others. CAS No. Magnolol: 528-43-8Honokiol: 35354-74-6. Purity: 2.0%~98.0% Magnolol & Honokiol HPLC. Mole weight: Magnolol: 266.33Honokiol: 266.33. Magnolia Extract (Standard); Magnolol: 528-43-8Honokiol: 35354-74-6; Magnolol: C18H18O2Honokiol: C18H18O2. Cat No: EXTW-010.
Nigroain-B antimicrobial peptide
Nigroain-B antimicrobial peptide is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog, Hylarana nigrovittata), and has antimicrobial activity. Synonyms: Phe-Thr-Met-Lys-Lys-Ser-Leu-Phe-Leu-Leu-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys. Grades: ≥97%. Molecular formula: C117H185N23O27S2. Mole weight: 2410.01.
Nigroain-C2
Nigroain-C2 is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog), and has antibacterial and antifungal activity. Synonyms: Phe-Lys-Thr-Trp-Lys-Arg-Pro-Pro-Phe-Gln-Thr-Ser-Cys-Trp-Gly-Ile-Ile-Lys-Glu. Grades: ≥95%. Molecular formula: C112H166N28O26S. Mole weight: 2352.78.
Nigroain-D antimicrobial peptide
Nigroain-D antimicrobial peptide is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog, Hylarana nigrovittata), and has antimicrobial activity. Synonyms: Phe-Thr-Met-Lys-Lys-Ser-Leu-Leu-Leu-Ile-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys-Glu-Gln-Glu-Arg. Grades: ≥96%. Molecular formula: C135H221N31O36S2. Mole weight: 2918.55.
Nigroain-E antimicrobial peptide
Nigroain-E antimicrobial peptide is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog, Hylarana nigrovittata), and has antimicrobial activity. Synonyms: Phe-Thr-Met-Lys-Lys-Ser-Pro-Leu-Leu-Leu-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys. Grades: ≥97%. Molecular formula: C113H183N23O27S2. Mole weight: 2359.95.
Nigroain-H antimicrobial peptide
Nigroain-H antimicrobial peptide is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog, Hylarana nigrovittata), and has antimicrobial activity. Synonyms: Phe-Thr-Met-Lys-Lys-Ser-Leu-Leu-Phe-Ile-Phe-Phe-Leu-Gly-Thr-Ile-Ser-Leu-Ser-Leu-Cys. Grades: ≥97%. Molecular formula: C117H185N23O27S2. Mole weight: 2410.01.
Nigroain-K2
Nigroain-K2 is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog), and has antibacterial and antifungal activity. Synonyms: Ser-Leu-Trp-Glu-Thr-Ile-Lys-Asn-Ala-Gly-Lys-Gly-Phe-Ile-Leu-Asn-Ile-Leu-Asp-Lys-Ile-Arg-Cys-Lys-Val-Ala-Gly-Gly-Cys-Lys-Thr (Disulfide bridge: Cys23-Cys29). Grades: ≥95%. Molecular formula: C151H252N42O41S2. Mole weight: 3376.05.
Nigroain-L antimicrobial peptide
Nigroain-L antimicrobial peptide is an antimicrobial peptide found in Rana nigrovittata (Black-striped frog, Hylarana nigrovittata), and has antimicrobial activity. Synonyms: Phe-Thr-Met-Lys-Lys-Ser-Leu-Phe-Leu-Ile-Leu-Phe-Leu-Gly-Ala-Ile-Pro-Leu-Ser-Met-Cys. Grades: ≥97%. Molecular formula: C114H185N23O25S3. Mole weight: 2374.04.
Oxalic Acid
While Oxalic Acid is widely recognized for its ability to eliminate iron oxide or rust stains from metal surfaces, it possesses a diverse range of applications. It can serve as a laundry rinse, wood-bleaching agent, calcium deposit remover, paint stripper, component in ink production, ink stain remover, stone cleaning and polishing agent, photographic film developer, and textile dyeing agent. Uses: Cleaning, Dyeing, Electroplating. Alternative Names: Dicarboxylic Acid, Ethanedionic Acid, Ethanedoic Acid, Oxalic Acid, Oxalic Acid Dihydrate. CAS No. 6153-56-6. Pack Sizes: 55 lb.
USA
Pelophylaxin-4
Pelophylaxin-4 is an antimicrobial peptide found in Rana fukienensis (Skin secretion, Pelophylax plancyi fukienensis, Fukien gold-striped pond frog), and has antimicrobial activity. Synonyms: Pelophylaxin 4; Ile-Leu-Pro-Phe-Leu-Ala-Gly-Leu-Phe-Ser-Lys-Ile-Leu-NH2. Grades: >98%. CAS No. 877458-39-4. Molecular formula: C73H119N15O14. Mole weight: 1430.82.
Sodium Hydroxide / Caustic Soda Beads
Sodium Hydroxide, also known as Caustic Soda or Lye, is used in all kinds of chemical processes. Because of the bead form, there is no dust scattering when handling the material and the solution rate is much quicker than other forms. Caustic Soda is widely used in many different industrial, commercial, and manufacturing applications like water treatment, chemical blending, detergents and more. Uses: Water Treatment, Detergents, Cleaners, pH Control, Scale & Corrosion Control, Paint Strippers. Alternative Names: NaOH, Caustic Soda, Sodium Hydroxide, Caustic, Lye. CAS No. 1310-73-2. Pack Sizes: 50 Lb, 500 Lb Drums.
USA
TETRAMETHYLAMMONIUM HYDROXIDE, SOLUTION1.0 Mol/L in WATER, REAGENT (ACS)
Industry Application Role/benefit Organic silicon Production of dimethyl silicone oil, organic silicon resin, silicon rubber, etc. Catalyst/removed easily; no pollution to the products Chemical analysis Polarography experiment Polarographic reagent Thermochemolysis to study fungal degradation of wood Analytical reagent Chemical purification Removal of metal elements Ash free alkali/source of base; make the metal elements precipitated Electron Production of computer silicon chip Brightening agent; anisotropic etching agent; cleaning agent; photoresist developer Printing of circuit board Cleaning agent Semiconductor manufacturing Chemical stripper Others Synthesis of ferrofluid Surfactant/ inhibit nanoparticle aggregation Synthesis of zeolite Structure directing agent. Group: Ammonium ionic liquids. Alternative Names: Tetramethylammonium hydroxide solution, ~25% in H2O; tetra methyl ammonium hydroxide; 75-59-2; Tetrametiloamonio hydroxido; Tetramethylammonium hydroxide solution, 25 wt. % in methanol; Tetrametanoamonio hydroxido; A838458; DB-050413; tetramethylammoniumhydroxide; AC1Q29QX. CAS No. 75-59-2. Molecular formula: C4H13NO. Mole weight: 91.154g/mol. IUPACName: tetramethylazanium;hydroxide. Canonical SMILES: C[N+](C)(C)C.[OH-]. Density: Specific gravity of solution approximately 1.00 at 24 deg C/4 deg C. ECNumber: 200-882-9. Catalog: ACM75592.
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