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A non-steroidal anti-inflammatory compound. An inhibitor of cyclooxygenase that is also a substrate for peroxidation by cyclooxygenase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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Phenylbutazone
Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent. Several studies have investigated Phenylbutazone as an anti-inflammatory agent and its role in mediating prostaglandin synthesis. Phenylbutazone may be of interest regarding research into anti-proliferative effects as well, especially in colorectal cancer studies. In studies with human colon cancer cell lines investigating anti-proliferative capabilities of NSAIDs, Phenylbutazone was noted to have intermediate anti-proliferative potency as compared to other NSAIDs. Phenylbutazone is an inhibitor of Cox (cyclooxygenase) that is also a substrate for peroxidation by Cox. Applications: An inhibitor of cox. Group: Coenzymes. CAS No. 50-33-9. Purity: ≥99%. Mole weight: 308.38. Form: Solid. Phenylbutazone; 50-33-9. Cat No: COEC-069.
Phenylbutazone
Phenylbutazone is an efficient reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). Phenylbutazone, a hepatotoxin, is a nonsteroidal anti-inflammatory agent (NSAID). Phenylbutazone induces muscle blind-like protein 1 (MBNL1) expression and has the potential for ankylosing spondylitis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-33-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0230.
Phenylbutazone
Phenylbutazone is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis. In the United States and United Kingdom, it is no longer approved for human use, as it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. Synonyms: Butazolidine. Grades: >98%. CAS No. 50-33-9. Molecular formula: C19H20N2O2. Mole weight: 308.37.
Phenylbutazone-d10(diphenyl-d10)
Heterocyclic Organic Compound. CAS No. 1219794-69-0. Molecular formula: 318.44. Purity: 98 atom % D. Catalog: ACM1219794690.
Phenylbutazone-d9
Phenylbutazone-d9. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Phenylbutazone Impurity 2
Phenylbutazone Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H14N2O2. Mole Weight: 242.28. Catalog: APB12281.
Phenylbutazone Impurity 3
Phenylbutazone Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H16N2O2. Mole Weight: 244.29. Catalog: APB12282.
Phenylbutazone Impurity B
An impurity of Phenylbutazone which is used as a non-steroidal anti-inflammatory agent for the treatment of chronic pain, including the symptoms of arthritis but it can cause severe adverse effects such as suppression of white blood cell production and aplastic anemia. Grades: > 95%. Molecular formula: C19H20N2O3. Mole weight: 324.38.
4-Hydroxy phenylbutazone. Group: Biochemicals. Alternative Names: 4-Butyl-4-hydroxy-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-4-butyl-4-hydroxypyrazolidine-3,5-dione; NSC 382672. Grades: Highly Purified. CAS No. 16860-43-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C19H20N2O3. US Biological Life Sciences.
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4-Hydroxy Phenylbutazone
4-Hydroxy Phenylbutazone. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Phenylbutazone Imp. B (EP),4-Butyl-4-hydroxy-1,2-diphenylpyrazolidine-3,5-dione. CAS No. 16860-43-8. IUPAC Name: 4-butyl-4-hydroxy-1,2-diphenylpyrazolidine-3,5-dione. Molecular Formula: C19H20N2O3. Mole Weight: 324.37. Catalog: APS16860438. SMILES: CCCCC1 (O)C (=O)N (N (C1=O)c2ccccc2)c3ccccc3. Format: Neat.
gamma-Hydroxy phenylbutazone
gamma-Hydroxy phenylbutazone. Group: Biochemicals. Alternative Names: 4-(3-Hydroxybutyl)-1,2-diphenyl-3,5-pyrazolidinedione; 1, 2-Diphenyl-3, 5-dioxo-4- (3-hydroxybutyl) pyrazolidine. Grades: Highly Purified. CAS No. 568-76-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H20N2O3. US Biological Life Sciences.
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12-Aminolauric Acid
12-Aminolauric Acid is an amino acid used as a reagent in organic synthesis of several compounds including phenylbutazone which is a new long-acting agent which displays improved pharmacokinectics based on human serum albumin as a drug carrier. Group: Biochemicals. Grades: Highly Purified. CAS No. 693-57-2. Pack Sizes: 1g, 5g. Molecular Formula: C12H25NO2, Molecular Weight: 215.33. US Biological Life Sciences.
Worldwide
Amicoumacin A
It is produced by the strain of Bacillus pumilus BN-103. It has anti-gram-positive bacterial activity and can inhibit foot paw edema (inflammation) caused by carrageenan in rats, which is similar to Phenylbutazone, and has a stronger effect on preventing gastric ulcer in rats than Sulpiride. Synonyms: Antibiotic BN 103; (3S)-3alpha-[(S)-1-[[(2S,3S,4S)-1,6-Dioxo-2,3-dihydroxy-4,6-diaminohexyl]amino]-3-methylbutyl]-8-hydroxy-3,4-dihydro-1H-2-benzopyran-1-one. CAS No. 56592-30-4. Molecular formula: C20H29N3O7. Mole weight: 423.46.
Azobenzene
Impurity in the production of Phenylbutazone. Group: Biochemicals. Alternative Names: 1,2-Diphenyldiazene; A 15073; Azobenzide; Azobenzol; Azobisbenzene; Benzeneazobenzene; Diphenyldiazene; Diphenyldiimide; NSC 2102; Phenylazobenzene. Grades: Highly Purified. CAS No. 103-33-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ethyl 2-?Carbethoxy-?5-?ketohexanoate
Ethyl 2-?Carbethoxy-?5-?ketohexanoate is an intermediate in the synthesis of γ-Hydroxy Phenylbutazone (H940070), a metabolite of Kebuzone (K155300), an antirheumatic agent. Group: Biochemicals. Alternative Names: Ethyl 2-Ethoxycarbonyl-5-oxohexanoate; NSC 75766; Diethyl 3-Oxobutylmalonate; (3-Oxobutyl)-propanedioic Acid; 2-(3-Oxobutyl)propanedioic Acid 1,3-Diethyl Ester. Grades: Highly Purified. CAS No. 4761-26-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Feprazone
Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA2370; Prenazone; Zepelin. CAS No. 30748-29-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-114911.
Mofebutazone
Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2210-63-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W009640.
Oxyphenbutazone
Oxyphenbutazone, a metabolite of Phenylbutazone, is a non-steroidal anti-inflammatory agent. Uses: Anti-inflammatory agents, non-steroidal; anti-inflammatory agents, topical. Synonyms: 4-butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione; oxyphenbutazone; Oxiphenbutazone; Oxyphenylbutazone; Oxifenylbutazon; Oxazolidin. Grades: > 95%. CAS No. 129-20-4. Molecular formula: C19H20N2O3. Mole weight: 324.38.
Oxyphenbutazone
Oxyphenbutazone is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect. Oxyphenbutazone is an orally active non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1355A.
Suxibuzone
Suxibuzone is a compound used for the study of joint and muscle pain, and it is a prodrug of the non-steroidal anti-inflammatory drug Phenylbutazone. Uses: Scientific research. Group: Signaling pathways. CAS No. 27470-51-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1079.
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