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| Product | Description | |
|---|---|---|
| Platelet-Derived Growth Factor-AA human | PDGF-AA, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. |  |
| Platelet-Derived Growth Factor-AB human | PDGF-AB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Platelet-Derived Growth Factor-BB from rat | PDGF-BB, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Platelet-Derived Growth Factor from porcine platelets | PDGF, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Platelet-Derived Endothelial Cell Growth Factor human | recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| 1-[2-[5- (2-Methoxyethoxy) benzimidazol-1-yl]quinolin-8-yl]piperidin-4-ylamine | 1-[2-[5- (2-Methoxyethoxy) benzimidazol-1-yl]quinolin-8-yl]piperidin-4-ylamine exhibits antiangiogenic and antitumor properties. It is an inhibitor of platelet-derived growth factor receptor β (PDGFR- β). Group: Biochemicals. Grades: Highly Purified. CAS No. 343787-29-1. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C24H27N5O2, Molecular Weight: 417.5. US Biological Life Sciences. |  Worldwide |
| 1-Stearo-2-linolein | 1-Stearo-2-linolein is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 27095-10-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences. | Worldwide |
| 1-Stearo-2-linolein-d5 | 1-Stearo-2-linolein-d5 is labelled 1-Stearo-2-linolein (S686465) which is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C39H67D5O5, Molecular Weight: 626.02. US Biological Life Sciences. | Worldwide |
| 1-Stearoyl-2-linoleoyl-sn-glycerol | 1-Stearoyl-2-linoleoyl-sn-glycerol is used in the study of the influence of platelet-derived growth factor (PDGF) on diacylglycerol phosphorylation in Swiss 3T3 cells. It is also a possible protein kinase C activator. Group: Biochemicals. Grades: Highly Purified. CAS No. 34487-26-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C39H72O5, Molecular Weight: 620.99. US Biological Life Sciences. | Worldwide |
| AC710 | AC710 is a potent, selective platelet-derived growth factor receptor-family kinase inhibitor with potential anticancer activity. AC710 is now a preclinical development candidate. Synonyms: AC 710; AC-710. Grade: >98%. CAS No. 1351522-04-7. Molecular formula: C31H42N6O4. Mole weight: 562.7. |  |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Synonyms: AG126; AG-126; Tyrphostin AG 126; UNII-7YA4AMD1JC; Tyrphostin A 10; alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile. Grade: 95%. CAS No. 118409-62-4. Molecular formula: C10H5N3O3. Mole weight: 215.16. | |
| AG1295 | Tyrphostin AG 1295 is a selective inhibitor of PDGFR (platelet-derived growth factor receptor) protein tyrosine kinase (PDGF-receptor PTK)(IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 μM) in Swiss/3T3 cells. Synonyms: AG1295; AG 1295; AG 1295; NSC 380341; NSC380341; NSC-380341; Tyrphostin AG 1295. Grade: >98%. CAS No. 71897-07-9. Molecular formula: C16H14N2. Mole weight: 234.30. | |
| AG 1295 - CAS 71897-07-9 | A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PDGF-dependent DNA synthesis (IC?? = 2.5 μM) in Swiss/3T3 cells. Group: Fluorescence/luminescence spectroscopy. | |
| AG 1478 - CAS 175178-82-2 | A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase. Group: Fluorescence/luminescence spectroscopy. | |
| AG 17 - CAS 10537-47-0 | Anti-proliferative agent that acts as a selective inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC?? = 500 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Ansornitinib | Ansornitinib is an orally active dual kinase inhibitor that inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor (VEGFR2). Ansornitinib can be used as an antifibrotic agent in lung, liver, kidney, and gastrointestinal fibrotic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ANG-3070. CAS No. 1448874-96-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147243. |  |
| Barnidipine hydrochloride | Barnidipine (Mepirodipine) hydrochloride is an L-type calcium antagonist ( CaA ) with high affinity for [ 3 H] initrendipine binding sites ( K i = 0.21 nmol/L, has selective action against CaA receptors. Barnidipine hydrochloride is an orally active antihypertensive agent that can reduce the level of platelet-derived growth factor B-chain mRNA and peripheral vascular resistance [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepirodipine hydrochloride; YM-09730-5. CAS No. 104757-53-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107322. | |
| BLZ945 | BLZ945 is an orally active, potent and selective CSF-1R inhibitor, which inhibits CSF-1R activity with an IC50 of 1nM and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-KIT and Platelet-derived Growth Factor Receptor beta (PDGFRb). Synonyms: sotuletinib; BLZ 945; BLZ-945. Grade: >98%. CAS No. 953769-46-5. Molecular formula: C20H22N4O3S. Mole weight: 398.48. | |
| Chrysoeriol | Chrysoeriol is a natural compound isolated from the herbs of Medicago sativa. Chrysoeriol can potently inhibit the induction of nitric oxide synthase by blocking activator protein 1 (AP-1) activation and its anti-inflammatory effects. Chrysoeriol can induce nod genes in rhizobium meliloti. Chrysoeriol can inhibit the downstream signal transduction pathways of platelet-derived growth factor (PDGF)-Rbeta, including ERK1/2, p38, and Akt phosphorylation, which suggests that chrysoeriol may be used for the prevention and treatment of vascular diseases during restenosis after coronary angioplasty. Synonyms: 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 4',5,7-Trihydroxy-3'-methoxyflavone; 3'-Methoxy-4',5,7-trihydroxyflavone; 3'-Methoxyapigenin; 3'-O-Methylluteolin; 5,7,4'-Trihydroxy-3'-methoxyflavone; Chrysoriol; Luteolin 3'-Methyl Ether; Scoparol; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-. Grade: 98.0%. CAS No. 491-71-4. Molecular formula: C16H12O6. Mole weight: 300.27. | |
| CP-547632 | CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively). It is selective relative to epidermal growth factor receptor, platelet-derived growth factor , and other related TKs. It also inhibits VEGF-stimulated autophosphorylation of VEGFR-2 in a whole cell assay with an IC50 value of 6 nM. After oral administration of CP-547,632 to mice bearing NIH3T3/H-ras tumors, VEGFR-2 phosphorylation in tumors was inhibited in a dose-dependent fashion (EC50 590 ng/ml). CP-547,632 is a well-tolerated, orally-bioavailable inhibitor presently under clinical investigation for the treatment of human malignancies. Synonyms: CP547632; CP 547632; CP-547632; PAN90806; PAN 90806; PAN-90806; CP632; OSI632; CP 632; OSI 632; CP-632; OSI-632. CAS No. 252003-65-9. Molecular formula: C20H24BrF2N5O3S. Mole weight: 532.405. | |
| Crenolanib | Crenolanib is an orally bioavailable small molecule, targeting the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Crenolanib binds to and inhibits PDGFR, which may result in the inhibition of PDGFR-related signal transduction pathways, and, so, the inhibition of tumor angiogenesis and tumor cell proliferation. PDGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to cell migration and the development of the microvasculature. Synonyms: CP 868596; CP868596; CP-868596; ARO 002; RO-002; RO002; Crenolanib. CAS No. 670220-88-9. Molecular formula: C26H29N5O2. Mole weight: 443.551. | |
| DMPQ dihydrochloride | DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC 50 of 80 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1123491-15-5. Pack Sizes: 1 mg. Product ID: HY-108627. | |
| Esculetin | Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 305-01-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0284. | |
| Henatinib | Henatinib inhibits vascular endothelial growth factor receptor type 2 (VEGFR2), a tyrosine kinase receptor upregulated in many tumor cells that plays a key role in angiogenesis. This may result in an inhibition of angiogenesis and eventually tumor cell proliferation. Henatinib, structurally similar to sunitinib, also inhibits, though to a lesser extent, mast/stem cell growth factor receptor (c-Kit) and, platelet-derived growth factor receptor (PDGFR) alpha and beta. Synonyms: (R,Z)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-5-(2-hydroxy-3-morpholin-4-yl-propyl)-3-methyl-5,6,7,8-tetrahydro-1H-pyrrolo[3,2-c]azepin-4-one. CAS No. 1239269-51-2. Molecular formula: C25H29FN4O4. Mole weight: 468.53. | |
| Imatinib free base | Imatinib is a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket located within tyrosine kinases (TK), thereby inhibiting ATP binding and preventing phosphorylation and the subsequent activation of growth receptors and their downstream signal transduction pathways. This agent inhibits TK encoded by the bcr-abl oncogene as well as receptor TKs encoded by the c-kit and platelet-derived growth factor receptor (PDGFR) oncogenes. Imatinib was approved for medical use in the United States in 2001. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGP 57148; CGP57148; CGP-57148; CGP57148B; CGP-57148B; CGP 57148B; STI571; STI-571; STI 571. Product Category: Inhibitors. Appearance: White to off-white to brownish or yellowish tinged crystalline powder. CAS No. 152459-95-5. Molecular formula: C29H31N7O. Mole weight: 493.62. Purity: >98%. IUPACName: N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide. Canonical SMILES: O=C(NC1=CC=C(C)C(NC2=NC=CC(C3=CC=CN=C3)=N2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4. Product ID: ACM152459955. Alfa Chemistry ISO 9001:2015 Certified. |  |
| JNJ-10198409 | JNJ-10198409 is a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor ( IC 50 =2 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. JNJ-10198409 has good activity against PDGFR-β kinase ( IC 50 =4.2 nM) and PDGFR-α kinase ( IC 50 =45 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 627518-40-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-W011266. | |
| mitogen-activated protein kinase kinase | This enzyme is a dual-specific protein kinase and requires mitogen-activated protein kinase kinase kinase (MAPKKK) for activation. It is required for activation of EC 2.7.11.24, mitogen-activated protein kinase. Phosphorylation of MEK1 by Raf involves phosphorylation of two serine residues. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury. Group: Enzymes. Synonyms: MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK . Enzyme Commission Number: EC 2.7.12.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3162; mitogen-activated protein kinase kinase; EC 2.7.12.2; MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK kinase; MAP2K; MAPKK; MAPKK1; MEK; MEK1; MEK2; MKK; MKK2; MKK4; MKK6; MKK7; STK27. Cat No: EXWM-3162. |  |
| ON-123300 | ON123300 is a potent multikinase inhibitor and may be potential useful for brain tumor chemotherapy. ON123300 strongly inhibits Ark5 and CDK4, as well as growth factor receptor tyrosine kinases such as β-type platelet-derived growth factor receptor (PDGFRβ). ON123300 inhibits U87 glioma cell proliferation with an IC(50) 3.4 ± 0.1 μmol/L. ON123300 exhibits potent activity against mantle cell lymphomas (MCLs) both in vitro and in vivo. ON123300 might be an effective agent in MCL, including ibrutinib-resistant forms of the disease. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ON-123300; ON 123300; ON123300; Narazaciclib. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1357470-29-1. Molecular formula: C24H27N7O. Mole weight: 429. Purity: >98%. IUPACName: 8-cyclopentyl-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carbonitrile. Canonical SMILES: N#CC1=CC2=CN=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C2N(C5CCCC5)C1=O. Product ID: ACM1357470291. Alfa Chemistry ISO 9001:2015 Certified. | |
| Petunidin chloride | Petunidin chloride is an O-methylated anthocyanidin derived from delphinidin. Petunidin chloride binds with and suppresses the activity of focal adhesion kinase and to inhibit platelet-derived growth factor-induced aortic smooth muscle cell migration, which may confer a protective effect against atherosclerosis. Uses: Scientific research. Group: Natural products. CAS No. 1429-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126410. | |
| Radotinib-[d6] | Radotinib-[d6] is deuterium labelled Radotinib. Radotinib, also known as IY-5511, is a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Synonyms: 4-(Methyl-d3)-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide-2,5,6-d3. CAS No. 2754051-83-5. Molecular formula: C27H15D6F3N8O. Mole weight: 536.55. | |
| Sennoside B | Sennoside B is a potent and orally active platelet-derived growth factor (PDGF) inhibitor. Sennoside B inhibits cell proliferation and the expression of phosphorylation of PDGFR-β, STAT-5, AKT and ERK induced by PDGF-BB. Sennoside B shows gastroprotective activities. Sennoside B has the potential for the research of gastritis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 128-57-4. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-N0366. | |
| Sunitinib Maleate (Sutent, Sunitinib Malate, SU-11248, PHA-290940AD, PNU-290940AD) | A multi-kinase inhibitor targeting several receptor tyrosine kinases (RTK). Sunitinib and its active metabolite (SU012662) are selective inhibitors of multiple receptor tyrosine kinases, including platelet-derived growth factor receptor and vascular endothelial growth factor receptor, that are associated with tumor growth and angiogenesis. Group: Biochemicals. Alternative Names: Sutent. Grades: Highly Purified. CAS No. 341031-54-7. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
| Tafetinib | Tafetinib (SIM010603) is an oral multi-targets receptor tyrosine kinases inhibitor. Tafetinib inhibits stem cell factor receptor (Kit) , vascular endothelial growth factor receptor-2 (VEGFR-2) , platelet-derived growth factor receptor-β (PDGFR-β) , glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET) , and Fms-like tyrosine kinase-3 (FLT3) with IC 50 values between 5.0 and 68.1 nmol/l. Tafetinib inhibits the phosphorylation of PDGFR-β and VEGFR-2. Tafetinib inhibits endothelial cell proliferation, endothelial cells chemotaxis, and corneal angiogenesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIM010603. CAS No. 1032265-57-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-116116. | |
| thymidine phosphorylase | The enzyme in some tissues also catalyses deoxyribosyltransferase reactions of the type catalysed by EC 2.4.2.6, nucleoside deoxyribosyltransferase. Group: Enzymes. Synonyms: pyrimidine phosphorylase; thymidine-orthophosphate deoxyribosyltransferase; animal growth regulators, blood platelet-derived endothelial cell growth factors; blood platelet-derived endothelial cell growth factor; deoxythymidine phosphorylase; gliostatins; pyrimidine deoxynucleoside phosphorylase; thymidine:phosphate deoxy-D-ribosyltransferase. Enzyme Commission Number: EC 2.4.2.4. CAS No. 9030-23-3. Thymidine Phosphorylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2668; thymidine phosphorylase; EC 2.4.2.4; 9030-23-3; pyrimidine phosphorylase; thymidine-orthophosphate deoxyribosyltransferase; animal growth regulators, blood platelet-derived endothelial cell growth factors; blood platelet-derived endothelial cell growth factor; deoxythymidine phosphorylase; gliostatins; pyrimidine deoxynucleoside phosphorylase; thymidine:phosphate deoxy-D-ribosyltransferase. Cat No: EXWM-2668. | |
| Thymidine Phosphorylase from Escherichia coli, Recombinant | An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays. Applications: ...hosphate deoxy-D-ribosyltransferase; EC 2.4.2.4; 9030-23-3. Enzyme Commission Number: EC 2.4.2.4. CAS No. 9030-23-3. Thymidine Phosphorylase. Activity: Type I, > 900 units/mL, aseptically filled; Type II, > 500 units/mL. Storage: 2-8°C. Form: buffered aqueous solution, Solution in 0.5 M potassium phosphate containing 2 mM uracil, 0.02% sodium azide and bovine serum albumin. Source: E. coli. Species: Escherichia coli. thymidine phosphorylase; pyrimidine phosphorylase; thymidine-orthophosphate deoxyribosyltransferase; animal growth regulators, blood platelet-derived endothelial cell growth factors; blood platelet-derived endothelial cell growth factor; deoxythymidi | |
| Trapidil | Trapidil is a vasodilator, an antiplatelet active molecule with specificity for platelet-derived growth factor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-12008. CAS No. 15421-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1016. | |
| TSU-68 | TSU-68 is a inhibitor that targets vascular endothelial growth factor receptor 2, platelet-derived growth factor receptor β, and fibroblast growth factor receptor 1. The inhibitory effects of TSU-68 towards these growth factors lead to substantial antitumor activity and showed potential in its development in therapeutic uses. Group: Biochemicals. Alternative Names: (Z)-3-(2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic Acid; 3-[2,4-Dimethyl-5-[(2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propionic Acid; 3-[4-(2-Carboxyethyl)-3,5-dimethylpyrrol-2-methylidenyl]-2-indolinone; 5-[(1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid; NSC 702827; Orantinib; SU 6668. Grades: Highly Purified. CAS No. 252916-29-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Tyrphostin AG1296 | Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 ?M. Tyrphostin AG1296 inhibits signaling of human PDGF ?- and ?-receptors as well as of the related stem cell factor receptor (c-Kit). Tyrphostin AG1296 is also a potent inhibitor of FLT3, with an IC50 in the micromolar range[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG1296. CAS No. 146535-11-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13894. | |
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