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| Product | Description | |
|---|---|---|
| Pneumocandin A4 | Pneumocandin A4 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Synonyms: 10,12-Dimethyl-tetradecanoic acid {3-(2-carbamoyl-1-hydroxy-ethyl)-11,25-dihydroxy-15-(1-hydroxy-ethyl)-6-[2-(4-hydroxy-phenyl)-ethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaaza-tricyclo[22.3.0.0~9,13~]heptacos-18-yl}-amide. Molecular formula: C51H82N8O13. Mole weight: 1015.24. |  |
| Pneumocandin B0 | Pneumocandin B0 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Uses: Antifungal. Synonyms: L-688,786; L 688,786; L688,786; L-688786; L 688786; L688786; (3S)-(4R,5R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]- 4,5-dihydroxy-L-ornithyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-glutaminyl-3-hydroxy-L-proline (6?1)-Lactam. Grades: >98%. CAS No. 135575-42-7. Molecular formula: C50H80N8O17. Mole weight: 1065.21. | |
| Pneumocandin B0 | Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, notably Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of b-(1,3)- D-glucan, an essential component of the cell wall of susceptible fungi. Group: Biochemicals. Grades: Highly Purified. CAS No. 135575-42-7. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Pneumocandin B0 | Pneumocandin B0 (L-688786), the precursor of the antifungal agent Caspofungin acetate, is an antifungal agent belonging to the echinocandin family. Pneumocandin B0, derived from the flamentous fungus Glarea lozoyensis , is a synthetic intermediate of Cancidas [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: L-688786. CAS No. 135575-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17578. |  |
| Pneumocandin B2 | Pneumocandin B2 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Synonyms: 10,12-Dimethyl-tetradecanoic acid [3-(2-carbamoyl-1-hydroxy-ethyl)-6-[1,2-dihydroxy-2-(4-hydroxy-phenyl)-ethyl]-11,25-dihydroxy-15-(1-hydroxy-ethyl)-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaaza-tricyclo[22.3.0.0~9,13~]heptacos-18-yl]-amide. Molecular formula: C50H80N8O15. Mole weight: 1033.21. | |
| Pneumocandin Impurity 2 | Pneumocandin Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((2R, 6S, 9S, 11R, 12R, 14aS, 15S, 20S, 23S, 25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S, 2S)-1, 2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2, 11, 12, 15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. Molecular Formula: C50H80N8O17. Mole Weight: 1065.21. Catalog: APB01941. |  |
| Pneumocandin Impurity 3 | Pneumocandin Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((2R, 6S, 9S, 11R, 12R, 14aS, 15S, 16S, 20S, 23S, 25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S, 2S)-1, 2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2, 11, 12, 15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. Molecular Formula: C51H82N8O17. Mole Weight: 1079.24. Catalog: APB01942. | |
| Pneumocandin Impurity 4 | Pneumocandin Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((2R, 6S, 9S, 14aS, 15S, 16S, 20S, 23S, 25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2, 15-dihydroxy-6-((R)-1-hydroxyethyl)-23-(4-hydroxyphenethyl)-16-methyl-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. Molecular Formula: C51H82N8O13. Mole Weight: 1015.24. Catalog: APB01940. | |
| Pneumocandin Impurity 5 | Pneumocandin Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((2R, 6S, 9S, 11R, 12R, 14aS, 15S, 20S, 23S, 25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2, 11, 12, 15-tetrahydroxy-23-((R)-2-hydroxy-2-(4-hydroxyphenyl)ethyl)-6-((R)-1-hydroxyethyl)-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. Molecular Formula: C50H80N8O16. Mole Weight: 1049.21. Catalog: APB01938. | |
| Pneumocandin Impurity 7 | Pneumocandin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((2R, 6S, 9S, 11S, 12R, 16R, 20S, 23S, 25aS)-20-((S)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S, 2S)-1, 2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2, 11, 12, 16-tetrahydroxy-6-((R)-1-hydroxyethyl)-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. Molecular Formula: C50H80N8O17. Mole Weight: 1065.21. Catalog: APB01937. | |
| Pneumocandin Impurity 8 | Pneumocandin Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((2R, 6S, 9S, 11R, 12R, 14aS, 20S, 23S, 25aS)-20-((S)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S, 2S)-1, 2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2, 11, 12-trihydroxy-6-((R)-1-hydroxyethyl)-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. Molecular Formula: C50H80N8O16. Mole Weight: 1049.21. Catalog: APB01936. | |
| 1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 | 1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. Group: Biochemicals. Grades: Highly Purified. CAS No. 198706-35-3. Pack Sizes: 5mg, 10mg. Molecular Formula: C56H84N8O16S. US Biological Life Sciences. | Worldwide |
| 1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 | 1-[(4R,5R)-N2-(10,12-Dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate of Caspofungin acetate, which is an essential component of the cell wall of filamentous fungi. Synonyms: Pneumocandin B0, 1-[(4R,5R)-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-; 1H-Dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacycloheneicosine-20-propanamide, 23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-9-[(10,12-dimethyl-1-oxotetradecyl)amino]tetracosahydro-β,2,11,15-tetrahydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxo-12-(phenylthio)-, (βR, 2R, 6S, 9S, 11R, 12R, 14aS, 15S, 20S, 23S, 25aS)-. CAS No. 198706-35-3. Molecular formula: C56H84N8O16S. Mole weight: 1157.37. | |
| 1-[(4R,5R)-N2-(10,12-Dimethyl-N-tetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 | 1-[(4R,5R)-N2-(10,12-Dimethyl-N-tetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C56H86N8O15S. US Biological Life Sciences. | Worldwide |
| 1-[(4R,5R)-N2-(10,12-Dimethyl-N-tetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 | 1-[(4R,5R)-N2-(10,12-Dimethyl-N-tetradecyl)-4-hydroxy-5-(phenylthio)-L-ornithine]-pneumocandin B0 is an intermediate of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C56H86N8O15S. Mole weight: 1143.39. | |
| 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-2-L-serine-5-[(3R)-3-hydroxy-L-ornithine]-Pneumocandin B0 Bi-acetate | 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-2-L-serine-5-[(3R)-3-hydroxy-L-ornithine]-Pneumocandin B0 Bi-acetate is an intermediate of Caspofungin acetate, which is an essential component of the cell wall of filamentous fungi. Grades: >98%. Molecular formula: C55H94N10O19. Mole weight: 1199.39. | |
| 1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Hydrochloride | 1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Hydrochloride is an intermediate of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Synonyms: 1-[(4R,5S)-5-Phenylthio-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Hydrochloride; Pneumocandin B0 Deoxy Phenylthio Analog Hydrochloride; Pneumocandin B0, 1-[(4R)-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-, hydrochloride (1:1). CAS No. 935739-50-7. Molecular formula: C56H87ClN8O15S. Mole weight: 1179.85. | |
| 1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Hydrochloride | 1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. Group: Biochemicals. Grades: Highly Purified. CAS No. 935739-50-7. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C56H87ClN8O15S. US Biological Life Sciences. | Worldwide |
| Caspofungin Pneumocandin B0 | Caspofungin Pneumocandin B0. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (10R, 12S)-N-((2R, 6S, 9S, 11R, 12R, 14aS, 15S, 20S, 23S, 25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S, 2S)-1, 2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2, 11, 12, 15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. CAS No. 135575-42-7. Molecular Formula: C50H80N8O17. Mole Weight: 1065.21. Catalog: APB135575427. | |
| Caspofungin Pneumocandin C0 | Caspofungin Pneumocandin C0. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (10R, 12S)-N-((2R, 6S, 9S, 11R, 12R, 14aS, 16R, 20S, 23S, 25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S, 2S)-1, 2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2, 11, 12, 16-tetrahydroxy-6-((R)-1-hydroxyethyl)-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-9-yl)-10, 12-dimethyltetradecanamide. CAS No. 144074-96-4. Molecular Formula: C50H80N8O17. Mole Weight: 1065.21. Catalog: APB144074964. | |
| 20(3'-Oxo-caspofungin) Triflate Salt | 20(3'-Oxo-caspofungin) Triflate Salt is a derivative of Caspofungin acetate, which is an essential component of the cell wall of filamentous fungi. Synonyms: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-1,1,1-trifluoromethanesulfonate Pneumocandin B0; Caspofungin Impurity 5 Triflate Salt; Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-, 1,1,1-trifluoromethanesulfonate (1:x). Grades: >98%. CAS No. 1201042-11-6. Molecular formula: C52H86N10O16.xCHF3O3S. Mole weight: 1107.30 (free base). | |
| 20(3'-Oxo-caspofungin) Triflate Salt | 20(3'-Oxo-caspofungin) Triflate Salt is derived from Pneumocandin B0 (P645300), which is the major analogue of a family of lipopeptides isolated from several species of several different genera, such as Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Group: Biochemicals. Grades: Highly Purified. CAS No. 1201042-11-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C52H86N10O16 x(CHF3O3S), Molecular Weight: 1107.3015008. US Biological Life Sciences. | Worldwide |
| Caspofungin acetate | Caspofungin acetate is the first in a new class of antifungals that inhibits the synthesis of beta (1, 3)-d-glucan, an essential component of the cell wall of filamentous fungi. Synonyms: MK-0991; MK 0991; MK0991; caspofungin diacetate; Cancidas; L 743872; L 743873; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate. Grades: >98%. CAS No. 179463-17-3. Molecular formula: C56H96N10O19. Mole weight: 1213.42. | |
| Caspofungin Acetate | An echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections. Group: Biochemicals. Alternative Names: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate; Cancidas; Caspofungin Diacetate; L 743872; L 743873; MK 0991; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate. Grades: Highly Purified. CAS No. 179463-17-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N??O??, Molecular Weight: 1213.42. US Biological Life Sciences. | Worldwide |
| Caspofungin Acetate-d4 | Isotope labelled Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections. Group: Biochemicals. Alternative Names: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate-d4; Cancidas-d4; Caspofungin Diacetate-d4; L 743872-d4; L 743873-d4; MK 0991-d4; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate-d4. Grades: Highly Purified. CAS No. 1131958-73-0, Unlabelled: 179463-17-3. Pack Sizes: 500ug. Molecular Formula: C??H??D?N??O??, Molecular Weight: 1217.44. US Biological Life Sciences. | Worldwide |
| Caspofungin Impurity E | Caspofungin Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-((3R)-3-Hydroxy-L-Ornithine)-Pneumocandin B0. CAS No. 150283-04-8. Molecular Formula: C50H82N8O16. Mole Weight: 1051.23. Catalog: APB150283048. | |
| Des-(5-(threo-3-hydroxy-L-ornithine)) Caspofungin Acetate | Des-(5-(threo-3-hydroxy-L-ornithine)) Caspofungin Acetate is an impurity of Caspofungin acetate, which is an essential component of the cell wall of filamentous fungi. Synonyms: Caspofungin Acetate Impurity 7; Caspofungin Impurity 5; Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]pneumocandin B0. CAS No. 1404083-47-1. Molecular formula: C52H86N10O16. Mole weight: 1107.29. | |
| FR 179642 | FR 179642 is an impurity of Micafungin, which is an antifungal agent. Synonyms: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grades: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89. | |
| FR-179642 | FR-179642 is a cyclic peptide and an important intermediate in producing micafungin. Group: Others. Alternative Names: FR-133303; FR 133303; FR133303; FR-179642; FR 179642; FR179642; Micafungin FR-179642 impurity; Pneumocandin M1. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.9. Appearance: Solid powder. Purity: >98%. IUPACName: 5-((1S, 2S)-2-((2R, 6S, 9S, 11R, 12R, 14aS, 15S, 16S, 20S, 23S, 25aS)-9-amino-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-2, 11, 12, 15-tetrahydroxy-6-((R)-1-hydroxyethyl)-16-methyl-5, 8, 14, 19, 22, 25-hexaoxotetracosahydro-1H-dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacyclohenicosin-23-yl)-1, 2-dihydroxyethyl)-2-hydroxyphenyl hydrogen sulfate. Canonical SMILES: C[C@@H] (O)[C@@H]1NC (=O)[C@@H] (N)C[C@@H] (O)[C@@H] (O)NC (=O)[C@@H]2[C@@H] (O)[C@@H] (C)CN2C (=O)[C@@H] (NC (=O)[C@@H] (NC (=O)[C@@H]3C[C@@H] (O)CN3C1=O)[C@H] (O)[C@@H] (O)c4ccc (O)c (OS (=O) (=O)O)c4)[C@H] (O)CC (=O)N. Catalog: ACM168110449. |  |
| FR 901379 | FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; (2α,3β,4β)-(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-Proline Cyclic (6?1)-Peptide; 1H-Dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacycloheneicosine Cyclic Peptide Deriv. Grades: ≥90%. CAS No. 144371-88-0. Molecular formula: C51H82N8O21S. Mole weight: 1175.30. | |
| Micafungin | Micafungin, also known as FK463, is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. In a mouse model of septic A. fumigatus infection, although non-treated mice survived for a maximum of only 6 days, the survival rate of micafungin-treated mice (0.1 mg kg-1) increased to 20%, while the survival rate of mice treated with a combination of micafungin (0.1 mg kg-1) and KB425796-C (32 mg kg-1) increased to 100% during the 31-day post-infection period. Uses: Antifungal agents. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; Mycamine; FK463. Grades: >98%. CAS No. 235114-32-6. Molecular formula: C56H71N9O23S. Mole weight: 1270.27. | |
| O-Desulfo Micafungin | O-Desulfo Micafungin is an impurity of caspofungin or micafungin. Micafungin is a polyene antifungal medication used to treat and prevent invasive fungal infections including candidemia, abscesses and esophageal candidiasis. Synonyms: Micafungin (m1); Pneumocandin A0, 1-((4R,5R)-4,5-dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)-; 1-((4R,5R)-4,5-Dihydroxy-N2-(4-(5-(4-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-L-ornithine)-4-((4S)-4-(3,4-dihydroxyphenyl)-4-hydroxy-L-threonine)pneumocandin A0. CAS No. 539823-80-8. Molecular formula: C56H71N9O20. Mole weight: 1190.23. | |
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