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| Product | Description | |
|---|---|---|
| DNA-directed DNA polymerase | Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA polymerase I; DNA polymerase II; DNA polymerase III; DNA polymerase α; DNA polymerase β; DNA polymerase γ; DNA nucleotidyltransferase (DNA-directed); deoxyribonucleate nucleotidyltransferase; deoxynucleate polymerase; deoxyribonucleic acid . Enzyme Commission Number: EC 2.7.7.7. CAS No. 9012-90-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3281; DNA-directed DNA polymerase; EC 2.7.7.7; 9012-90-2; DNA polymerase I; DNA polymerase II; DNA polymerase III; DNA polymerase α; DNA polymerase β; DNA polymerase γ; DNA nucleotidyltransferase (DNA-directed); deoxyribonucleate nucleotidyltransferase; deoxynucleate polymerase; deoxyribonucleic acid duplicase; deoxyribonucleic acid polymerase; deoxyribonucleic duplicase; deoxyribonucleic polymerase; deoxyribonucleic polymerase I; DNA duplicase; DNA nucleotidyltransferase; DNA polymerase; DNA replicase; DNA-dependent DNA polymerase; duplicase; Klenow fragment; sequenase; Taq DNA polymerase; Taq Pol I; Tca DNA polymerase. Cat No: EXWM-3281. |  |
| DNA-directed RNA polymerase | Catalyses DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to α-amanitin, and the type of RNA synthesized. See also EC 2.7.7.19 (polynucleotide adenylyltransferase) and EC 2.7.7.48 (RNA-directed RNA polymerase). Group: Enzymes. Synonyms: RNA polymerase; RNA nucleotidyltransferas. Enzyme Commission Number: EC 2.7.7.6. CAS No. 9014-24-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3271; DNA-directed RNA polymerase; EC 2.7.7.6; 9014-24-8; RNA polymerase; RNA nucleotidyltransferase (DNA-directed); RNA polymerase I; RNA polymerase II; RNA polymerase III; C RNA formation factors; deoxyribonucleic acid-dependent ribonucleic acid polymerase; DNA-dependent ribonucleate nucleotidyltransferase; DNA-dependent RNA nucleotidyltransferase; DNA-dependent RNA polymerase; ribonucleate nucleotidyltransferase; ribonucleate polymerase; C ribonucleic acid formation factors; ribonucleic acid nucleotidyltransferase; ribonucleic acid polymerase; ribonucleic acid transcriptase; ribonucleic polymerase; ribonucleic transcriptase; RNA nucleotidyltransferase; RNA transcriptase; transcriptase; RNA nucleotidyltransferase I. | |
| DNA Polymerase Alpha from Human, Recombinant | DNA polymerase alpha also known as Pol α is an enzyme complex found in eukaryotes that is involved in initiation of DNA replication. The DNA polymerase alpha complex consists of 4 subunits: POLA1, POLA2, PRIM1, and PRIM2. Group: Enzymes. Synonyms: DNA polymerase alpha; DNA polymerase; Pol &alpha. Enzyme Commission Number: EC 2.7.7.7. CAS No. 9012-90-2. DNA Polymerase. Activity: 16,835 units/mg, 5 units/ul. Storage: Store at -80°CNote: Avoid multiple freeze / thaw cycles or frequent temperature changes. Species: Human. DNA polymerase alpha; DNA polymerase; Pol &alpha. Cat No: NATE-1922. | |
| DNA Polymerase for PAGE | DNA Polymerase for PAGE. Dna polymerase for page is purified from e. coliexpressing a cloned dna polymerase from thermus aquaticus. the enzyme consists of a single polypeptide with a molecular weight of approximately 94 kda. dna polymerase for page has 5?-3? dna polymerase activity and 5?-3? exonuclease activity. lt lacks 3?-5? exonuclease activity. this enzyme is supplied with unique buffer, and its pcr product is suitable for sds-page and agarose gel electrophoresis. Group: Cloning Enzymes. Purity: 2500U. Storage: Store at -20 ?. Cat No: CE-3004. | |
| DNA Polymerase I Klenow Fragment, Exo-Minus, Recombinant, 10X Reaction Buffer | DNA Polymerase I Klenow Fragment, Reaction Buffer (10X) supplied with D3941. Group: Molecular Biology. Grades: Molecular Biology Grade. Pack Sizes: 1ml. US Biological Life Sciences. |  Worldwide |
| DNA Polymerase I Klenow Fragment, Reaction Buffer (10X) | DNA Polymerase I Klenow Fragment, Reaction Buffer (10X) supplied with D3940. Group: Molecular Biology. Grades: Molecular Biology Grade. CAS No. 9012-90-2. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| DNA Polymerase I Reaction Buffer, 10X | Reaction Buffer (10X) for D3935. Group: Molecular Biology. Grades: Molecular Biology Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| DNA Polymerase, Pfu, Reaction Buffer, 10X | D3935-65B1(10X Reaction Buffer): Group: Molecular Biology. Grades: Purified. Pack Sizes: 10ml, . US Biological Life Sciences. | Worldwide |
| DNA Polymerase T4 Buffer, 5X | Reaction buffer for D3943: DNA Polymerase T4, Exo-Minus. Group: Molecular Biology. Pack Sizes: 350ul. US Biological Life Sciences. | Worldwide |
| HiFi DNA Polymerase | HiFi DNA Polymerase. Hifi dna polymerase contains ta dna polymerase and a proofreading 3-5 exonuclease.hifi dna polymerase provides higher specificity and higher amplification efficiency than ta dna polymerase. two different buffers are provided in the kit. hifi pcr buffer i is optimized for the amplification of genomic dna and hifi pcr buffer ii is optimized for the amplification of λdna, cdna or plasmid dna. extension rate is about 1-2 kb/min. template-independent a can be generated at the 3 end of the pcr product. amplification of genomic dna fragment up to 15 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3022. | |
| HiFi Pfu DNA Polymerase | HiFi Pfu DNA Polymerase. Hifi pfu dna polymerase is an engineered version of pfu dna polymerase with enhanced yield and higher fidelity. ehifi pfu dna polymerase possesses a proofreading 3'-5' exonuclease activity. hifi pfu dna polymerase offers high fidelity. extension rate is about 0.5 kb/min. amplification of genomic dna fragment up to 6 kb. amplification of plasmid dna fragment up to 10 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3001. | |
| KD Plus DNA Polymerase | KD Plus DNA Polymerase. Kd plus dna polymerase is a genetically modified high fidelity dna polymerase. this enzyme provides higher amplification capability than traditional pfu dna polymerase and fast amplification speed equal to taq dna polymerase (1 kb/min). due to strong 3-5 exonuclease activity, this enzyme offers 108-fold fidelity as compared to taq dna polymerase. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 100U; 200U. Storage: Store at -20 ?. Cat No: CE-3019. | |
| KOD DNA Polymerase from Thermococcus kodakaraensis, Recombinant | KOD is a high fidelity thermostable DNA polymerase that amplifies target DNA up to 6 kbp with superior accuracy and yield for PCR applications. The enzyme's 3'?5' exonuclease-dependent proofreading activity results in a lower PCR mutation frequency than any other commercially available DNA polymerase. The elongation rate and processivity are 5 times and 10 to 15 times higher, respectively, than for Pfu DNA polymerase, resulting in highly accurate and robust yield, in a short reaction time. Higher fidelity than pfu dna polymerase--excellent for cloninggreater yield--extension speed is 2x faster than taq dna polymerase and 5x faster than pfu dna polymerasehigher processivity--sequential nucleotide polymerization is 10- to 15-fold greater than pfu and tli dna polymerasesamplifies plasmid and lambda dna templates up to 6 kbpamplifies genomic dna templates up to 2 kbpno truncated amplification products. Group: Enzymes. Purity: > 90% homogeneous by SDS-PAGE. DNA Polymerase. Storage: at -20°C. Source: E. coli. Species: Thermococcus kodakaraensis. KOD DNA polymease; DNA polymease; KOD. Cat No: NATE-1632. | |
| Modified T7 RNA polymerase | A modified T7 RNA polymerase that orthogonally recognizes a non-natural promoter sequence: 5-TAATACCGGTCACTATA, where the underlined residues differ from wild-type. Group: Enzymes. Synonyms: CGG-R12-KIR. Enzyme Commission Number: EC 2.7.7.6. CAS No. 9014-24-8. Purity: > 98% (SDS-PAGE). Mole weight: 100.142 kDa. Storage: at -20 °C. Form: Liquid. CGG-R12-KIR; Non-Natural Promoter T7 Polymerase; modified T7 RNA polymerase; T7 RNA polymerase. Cat No: NATE-1698. | |
| Native E. coli RNA Polymerase, Holoenzyme | E. coli RNA Polymerase, Holoenzyme is the core enzyme saturated with sigma factor 70. The Holoenzyme initiates RNA synthesis from sigma 70 specific bacterial and phage promoters. E. coli RNA Polymerase, Core Enzyme consists of 5 subunits designated α, α, β?, β, and &omega. The enzyme is free of sigma factor and does not recognize any specific bacterial or phage DNA promoters. The enzyme retains the ability to transcribe RNA from nonspecific initiation sequences. Addition of sigma factors will allow the enzyme to initiate RNA synthesis from specific bacterial and phage promoters. Applications: Rna synthesis from e. coli promoter transcription initiation studies in vitro translation with purexpress. Group: Enzymes. Synonyms: E. coli RNA Polymerase, Holoenzyme; E. coli RNA Polymerase; RNA Polymerase; RNAP; RNApol; DNA-dependent RNA polymerase. RNAP. Mole weight: 400 kDa. Storage: at -20°C. Form: 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 0.1 mM EDTA, 1 mM dithiothreitol (DTT) and 50% glycerol. Source: E. coli. E. coli RNA Polymerase, Holoenzyme; E. coli RNA Polymerase; RNA Polymerase; RNAP; RNApol; DNA-dependent RNA polymerase. Cat No: NATE-1262. | |
| PARP (Poly ADP-Ribose Polymerase). Positive Control A | PARP (Poly ADP-Ribose Polymerase) Positive Control A. Group: Molecular Biology. Pack Sizes: 60ul. US Biological Life Sciences. | Worldwide |
| PARP (Poly ADP-Ribose Polymerase). Positive Control B | PARP (Poly ADP-Ribose Polymerase) Positive Control B. Group: Molecular Biology. Pack Sizes: 60 ul. US Biological Life Sciences. | Worldwide |
| Pfu DNA Polymerase | Pfu DNA Polymerase. Pfu dna polymerase is a fast, high fidelity and high processivity hot start dna polymerase. extension rate is about 2-4 kb/min. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3015. | |
| Phi29 DNA Polymerase | Phi29 DNA Polymerase. This product is a 74.4 kda purified recombinant protein inducibly expressed in e. coli carrying the φ29 dna polymerase gene. with high sensitivity and great synthesis ability, it can be used for whole genome amplification from a single cell. it possesses 3'?5' proofreading exonuclease activity to ensure high fidelity of resulting dna. its properties of multiple strand displacement and processive synthesis allow >10 kb lengths of amplification products from genome or plasmid dna, and enable rolling-circle replication of circular dna. · isothermal amplification. · high fidelity; high efficiency; high sensitivity; high yield. · random primers or specific n9 primers can be used. Group: DNA Modifying Enzymes. Purity: 250U; 5*250U. Storage: Store at -20°C. Cat No: ME-4001. | |
| Poly [ADP-ribose] polymerase 1 from Human, Recombinant | PARP-1, a nuclear enzyme that synthesizes ADP-ribose polymers from NAD, specifically binds Zn2+ and DNA, and recognizes single-strand breaks in DNA. It is involved in base excision repair, both short-patch and long-patch, rejoining DNA strand breaks and plays a role in p53 expression and activation. A high level of basal neuronal DNA damage and PARP activity has been reported in rat brain tissue. PARP-1 was shown to be required for HIV-1 integration into DNA. If PARP-1 is deficient there is no productive HIV-1 infection. Applications: Parp-1 is a nuclear enzyme that synthesizes adp-ribose polymers from nad+, specifically binds zn2+ and dna, and recognizes single-st...enosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase; EC 2.4.2.30. Enzyme Commission Number: EC 2.4.2.30. CAS No. 58319-92-9. Poly [ADP-ribose] polymerase 1. Storage: -20°C. Form: Supplied as a solution in 20 mM Tris-HCl, pH 8.0, 200 mM NaCl, 1 mM DTT, 0.1% Triton(TM)-X 100, 50 % glycerol, and 0.1 mg/ml BSA. Source: E. coli. Species: Human. PARP1; poly (ADP-ribose) synthase; ADP-ribosyltransferase (polymerizing); NAD ADP-ribosyltransferase; PARP; PARP-1; NAD+:poly (adenine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase (incorrect); NAD+:poly (adenosine-diphosphate-D-ribosyl)-acceptor ADP-D-ribosyl-transferase; EC 2.4.2.30. Cat No: NATE-0507. | |
| Poly(A) polymerase gamma (724-734) | Poly(A) polymerase gamma (724-734) is a peptide corresponding to residues 724-734 of Poly(A) polymerase gamma. Poly(A) polymerase gamma is responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA. Synonyms: PAP-gamma (724-734); Polynucleotide adenylyltransferase gamma (724-734); Signal recognition particle RNA-adenylating enzyme (724-734). |  |
| RNA-directed DNA polymerase | Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. RT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3261; RNA-directed DNA polymerase; EC 2.7.7.49; 9068-38-6; DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Cat No: EXWM-3261. | |
| RNA-directed RNA polymerase | Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase. Group: Enzymes. Synonyms: RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonuclei. Enzyme Commission Number: EC 2.7.7.48. CAS No. 9026-28-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3260; RNA-directed RNA polymerase; EC 2.7.7.48; 9026-28-2; RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonucleic acid replicase; ribonucleic acid-dependent ribonucleate nucleotidyltransferase; ribonucleic acid-dependent ribonucleic acid polymerase; ribonucleic replicase; ribonucleic synthetase; RNA replicase; RNA synthetase; RNA transcriptase; RNA-dependent ribonucleate nucleotidyltransferase; RDRP; RNA-dependent RNA polymerase; RNA-dependent RNA replicase; transcriptase. Cat No: EXWM-3260. | |
| [RNA-polymerase]-subunit kinase | The enzyme appears to be distinct from other protein kinases. It brings about multiple phosphorylations of the unique C-terminal repeat domain of the largest subunit of eukaryotic DNA-directed RNA polymerase (EC 2.7.7.6). The enzyme does not phosphorylate casein, phosvitin or histone. Group: Enzymes. Synonyms: CTD kinase; STK9. Enzyme Commission Number: EC 2.7.11.23. CAS No. 122097-00-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3143; [RNA-polymerase]-subunit kinase; EC 2.7.11.23; 122097-00-1; CTD kinase; STK9. Cat No: EXWM-3143. | |
| Speed Pfu DNA Polymerase | Speed Pfu DNA Polymerase. Speed pfu dna polymerase is a hot start, high fidelity and high processivity dna polymerase. speed pfu dna polymerase has an extension rate of up to 6 kb/min. speed pfu dna polymerase has high extension rate, fidelity, and amplification efficiency. extension rate is about 2-6 kb/min. amplification of genomic dna fragment up to 15 kb. amplification of plasmid dna fragment up to 20 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3016. | |
| T7 RNA polymerase | T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+ , T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9014-24-8. Pack Sizes: 1 KU; 5 KU. Product ID: HY-E70090. |  |
| TA DNA Polymerase | TA DNA Polymerase. Ta dna polymerase is a mixture of taq dna polymerase with a proofreading 3-5 exonuclease. the fidelity is equal to hifi pfu dna polymerase. the yield is equal to that from taq dna polymerase. it is more suitable for high fidelity ta cloning. ta dna polymerase offers 18-fold fidelity as compared to taq dna polymerase. extension rate is about 1-2 kb/min. template-independentacan be generated at the 3end of the pcr product. amplification of genomic dna fragment up to 8 kb. Group: Cloning Enzymes. Purity: 250U; 500U. Storage: Store at -20 ?. Cat No: CE-3024. | |
| Taq DNA polymerase | Taq DNA polymerase is a thermostable DNA polymerase that can be used in PCR [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304873-37-6. Pack Sizes: 500 U. Product ID: HY-E70086. | |
| Taq DNA Polymerase | Taq DNA Polymerase. Taq dna polymerase is purified from e. coli expressing a cloned dna polymerase from thermus aquaticus. the enzyme consists of a single polypeptide with a molecular weight of approximately 94 kda. taq dna polymerase has 5?-3? dna polymerase activity and 5?-3? exonuclease activity. it lacks 3?-5? exonuclease activity. taq dna polymerase is suitable for routine amplification. pcr products are unsuitable for page. extension rate is about 1-2 kb/min. template-independent a can be generated at the 3? end of the pcr product. amplification of genomic dna fragment up to 4 kb. Group: Cloning Enzymes. Purity: 500U; 2500U. Storage: Store at -20 ?. Cat No: CE-3003. | |
| 1-(2-Cyclopropylethyl)-6-fluorobenzo[d][1, 3]oxazine-2, 4-dione | Intermediate in the synthesis of HCV polymerase inhibitors. Group: Biochemicals. Alternative Names: 1-(2-Cyclopropylethyl)-6-fluoro-2H-3,1-benzoxazine-2,4(1H)-dione. Grades: Highly Purified. CAS No. 477933-12-3. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine | 1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)6-methylpurine, a remarkable antiviral compound, demonstrates its efficacy in combatting herpes simplex and varicella-zoster viruses. Through its robust inhibition of viral DNA polymerase, this agent dismantles viral replication processes, thereby alleviating associated symptoms. With its exceptional selectivity towards viral enzymes, this therapeutic option proves to be a commendable approach for managing viral infections among affected individuals. Synonyms: 6-Methylpurine-2'-deoxy-2'-fluoro-beta-D-arabinoriboside. Grades: ≥95%. CAS No. 2095417-72-2. Molecular formula: C11H13FN4O3. Mole weight: 268.24. | |
| 1-(2'-O-Acetyl-3',5'-bis-O-benzoyl-b-D-xylofuranosyl)-6-azauracil | 1-(2'-O-Acetyl-3',5'-bis-O-benzoyl-b-D-xylofuranosyl)-6-azauracil, a synthetic compound with antiviral and anticancer properties, offers a unique opportunity for biomedical research. It targets RNA replication in viruses and cancers, including hepatitis C virus and certain types of leukemia. With its potent inhibition of RNA polymerase, this product presents a promising avenue towards developing effective treatments for these diseases. Exploring the therapeutic potential of this compound could open up new doors for the field of medicine. Synonyms: 2'-O-Acetyl-3',5'-bis-O-benzoyl-6-aza-xylouridine; (2R,3S,4R,5R)-4-Acetoxy-2-((benzoyloxy)methyl)-5-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)tetrahydrofuran-3-yl benzoate; 2-(2-O-Acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione. Grades: ≥95%. CAS No. 161615-21-0. Molecular formula: C24H21N3O9. Mole weight: 495.44. | |
| 1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester | 1, ?2-?Piperidinedicarboxyl ?ic Acid 1-?(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-?[(R)?-?2-?methylpyrrolidin-?2-?yl]?-?1H-?benzimidazole-?4-?carboxamide (ABT-?888) as the Poly(ADP-?ribose) Polymerase (PARP) inhibitor for the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 28697-07-6. Pack Sizes: 25g, 100g. Molecular Formula: C14H17NO4, Molecular Weight: 263.29. US Biological Life Sciences. | Worldwide |
| 1-((2R,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | 1-((2R,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is an efficacious pharmaceutical compound that has been extensively studied to treat viral infections caused by herpes simplex virus (HSV), varicella-zoster virus (VZV), and cytomegalovirus (CMV). The remarkable feature of this drug is its ability to effectively inhibit viral DNA polymerase, thereby halting viral replication and preventing spread. As nucleoside analogue, it is a preferred choice for combination therapy to achieve superior antiviral potency. The exquisite chemical structure of this compound enables it to bind to the viral polymerase in a unique manner, conferring its remarkable therapeutic benefit. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| 1-(3-Fluoro-4-nitrobenzoyl)-2-imidazolidinone | 1-(3-Fluoro-4-nitrobenzoyl)-2-imidazolidinone is derived from 3-Fluoro-4-nitrobenzoic Acid (F595033), which is used in the synthesis of ABT-072, a non-nucleoside HCV NS5B polymerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1283965-40-1. Pack Sizes: 50mg, 250mg. Molecular Formula: C10H8FN3O4, Molecular Weight: 253.19. US Biological Life Sciences. | Worldwide |
| 1-(3'-O-Methyl-b-D-xylofuranosyl)cytosine | 1-(3'-O-Methyl-b-D-xylofuranosyl)cytosine, a formidable antiviral compound, has garnered significant attention in combating various viral infections. Its mechanism of action revolves around impeding the replication of viral genetic material by selectively hindering viral DNA polymerases. Remarkably, this agent has showcased exceptional efficacy against herpesviruses and poxviruses, thereby establishing itself as a paramount weapon in battling viral maladies. | |
| 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil - a remarkable pharmaceutical compound known for its potency against viral infections. Deemed an anti-DNA virus agent, this unique product is effective against formidable pathogens like herpes simplex virus (HSV), varicella-zoster virus (VZV), and even the notorious human immunodeficiency virus (HIV). By restraining viral DNA polymerase, it deftly curtails virus replication, ultimately conferring unparalleled therapeutic benefits. Grades: ≥95%. Molecular formula: C26H44N4O10P2. Mole weight: 634.60. | |
| 1,5-Isoquinolinediol | 1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. 1,5-Isoquinolinediol is also an inducible nitric oxide synthase (NOS2) inhibitor. 1,5-Isoquinolinediol significantly inhibited mitochondrial membrane potential loss, AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 1,5-Dihydroxyisoquinoline; Isoquinoline-1,5-diol; 5-Hydroxy-1(2H)-isoquinolinone; 5-Hydroxyisocarbostyril. Grades: 99%. CAS No. 5154-2-9. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| 1-(alpha-L-Threofuranosyl)thymine | 1-(alpha-L-Threofuranosyl)thymine is an analogue nucleoside with powerful antiviral properties, making it the ideal drug for treating herpes simplex virus and varicella-zoster virus infections. Its mechanism of action is remarkably sophisticated, as it irreversibly inhibits viral DNA polymerase, reducing viral replication and thereby suppressing viral load with utmost efficiency. Synonyms: 1-(α-L-Threofuranosyl)thymine; 1-((2R,3R,4S)-3,4-Dihydroxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 325683-84-9. Molecular formula: C9H12N2O5. Mole weight: 228.20. | |
| 1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine | 1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(b-D-xylofuranosyl)guanine is a remarkable antiviral medication proficient in managing a range of viral infections caused by herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus. Functioning by thwarting viral DNA polymerase and interrupting viral replication, this product exhibits exceptional proficiency in controlling herpes keratitis and encephalitis, as well as treating viral infections in immunocompromised patients. Its unparalleled potential in augmenting the immune response and suppressing pathological viruses results in its widespread application in medicinal microbiology. Synonyms: 1-Amino-7-cyclopropylmethyl-7,8-dihydro-8-oxo-9-(β-D-xylofuranosyl)guanine; 1,2-diamino-7-(cyclopropylmethyl)-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-7,9-dihydro-1H-purine-6,8-dione. Grades: ≥95%. CAS No. 2389988-22-9. Molecular formula: C14H20N6O6. Mole weight: 368.35. | |
| 1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine | 1-Amino-8-benzyloxy-9-(b-D-xylofuranosyl)guanine serves as an antiviral nucleoside analogue drug primarily used to mitigate herpes simplex virus infections. Its mechanism of action involves limiting the activity of viral DNA polymerase, which culminates in the hindrance of viral replication. This therapeutic option remains popular in managing herpes simplex virus infections affecting the immunocompromised and critically ill. Synonyms: 1-Amino-8-benzyloxy-9-(β-D-xylofuranosyl)guanine; 1,2-diamino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxypurin-6-one. Grades: ≥95%. CAS No. 2389988-20-7. Molecular formula: C17H20N6O6. Mole weight: 404.38. | |
| 1-(b-D-Xylofuranosyl)-5-methoxyuracil | 1-(b-D-Xylofuranosyl)-5-methoxyuracil, regarded as a potent and efficacious antiviral drug with its ability to manage and alleviate an array of viral infections such as Herpes simplex virus (HSV), Varicella zoster virus (VZV), and Epstein-Barr virus (EBV), operates to impede and hinder viral DNA polymerase, thwarting the replication of viral DNA and mitigating viral load within human anatomy. Synonyms: 1-(beta-D-Xylofuranosyl)-5-methoxyuracil; 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 5-Methoxy-1-(β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. Molecular formula: C10H14N2O7. Mole weight: 274.23. | |
| 1-(b-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine | 1-(b-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine, commonly known as an antiviral drug, is widely utilized for treating hepatitis B and hepatitis C. This agent has proven to be highly effective in improving liver function and reducing viral load, as demonstrated in numerous clinical studies. With its inhibitory effects on viral polymerase, it successfully impedes the replication process of notorious viruses, including those found in HIV-infected patients. Synonyms: 1-(beta-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine; 1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine. Grades: ≥95%. Molecular formula: C18H18F3N5O4. Mole weight: 425.36. | |
| 1-Benzylindole-3-carbaldehyde | 1-Benzylindole-3-carbaldehyde was patented as an oncogenic ras-specific cytotoxic Oncrasin compund for treatment of cancer and viral infections. It was also studied to show its inhibitory effect on RNA polymerase II as a potential anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 10511-51-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H13NO, Molecular Weight: 235.28. US Biological Life Sciences. | Worldwide |
| 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid | 1-? (Benzyloxycarbonyl) ?pyrrolidine-?3-?carboxylic Acid is a reagent used in the synthesis of cyclin-dependent kinase 4-inhibitors (CDK4) for cancer treatments. Also used towards the discovery of a potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer pased upon benzimidazole carboxamide moieties. Group: Biochemicals. Grades: Highly Purified. CAS No. 188527-21-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H15NO4, Molecular Weight: 249.26. US Biological Life Sciences. | Worldwide |
| 1-beta-D-Arabinofuranosylthymine | 1-beta-D-Arabinofuranosylthymine is a noteworthy nucleoside analog that administers antiviral action when used in the management of herpes simplex and varicella-zoster virus infections. Its mechanism of action involves zoning in on the viral DNA polymerase to halt viral replication. Uses: Antiviral agents. Synonyms: Arabinofuranosyl-5-methyluridine; 1-(β-D-Arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(β-D-arabinofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione; Spongothymidine; Arabinosylthymine; Thymine arabinoside. Grades: ≥95%. CAS No. 605-23-2. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| 1- β-D-Arabinofuranosyluracil-2-C-methyl | 1- β-D-Arabinofuranosyluracil-2-C-methyl is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 114262-49-6. Pack Sizes: 25mg, 250mg. Molecular Formula: C10H14N2O6, Molecular Weight: 258.23. US Biological Life Sciences. | Worldwide |
| 1- β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C | 1- β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C is the labeled analogue of 1- β-D-Arabinofuranosyluracil-2-C-methyl (A764005), an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1256490-38-6. Pack Sizes: 2.5mg, 75mg. Molecular Formula: C913CH11D3N2O6, Molecular Weight: 262.24. US Biological Life Sciences. | Worldwide |
| 1-Butyl-3-(1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone | Heterocyclic inhibitor of the RNA-dependent RNA polymerase enzyme transcribed by the Hepatitis C virus. Group: Biochemicals. Grades: Highly Purified. CAS No. 303776-83-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1'-epi-PSI-6130 | As an epimer of PSI-6130, 1'-epi-PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Molecular formula: C10H14FN3O4. Mole weight: 259.23. | |
| 1-epi-PSI-6130 | 1-epi-PSI-6130 is an epimer of PSI-6130 (P839680) which is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H14FN3O4, Molecular Weight: 259.23. US Biological Life Sciences. | Worldwide |
| 1,N6-Etheno-ara-adenosine | 1,N6-Etheno-ara-adenosine is a synthetic nucleoside analog commonly used in the biomedical industry to study the effects of oxidative damage to DNA. It can also be used to investigate the mechanisms of inhibition and reparation of DNA polymerases, making it valuable in the development of cancer therapies. Synonyms: (2R,3S,4S,5R)-2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yloxolane-3,4-diol. Grades: ≥95%. CAS No. 2095417-09-5. Molecular formula: C12H13N5O4. Mole weight: 291.26. | |
| 1-O -Acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside | 1-O-Acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside is an intriguing fluorinated nucleoside derivative, firmly established in HCV research as a potent inhibitor of HCV NS5B polymerase that plays an indispensable role in HCV replication. 1-O-Acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside has shown a low cytotoxicity while efficiently targeting HCV NS5B polymerase, thus, demonstrating a remarkable specificity. These combined characteristics project a promising potential for 1-O-acetyl-2,5-di-O-benzoyl-3-fluoro-3-deoxy-b-D-ribofuranoside in the treatment of HCV infection, indicating its remarkable significance to medical treatment through strict HCV inhibition. CAS No. 122654-34-6. | |
| 1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside | 1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside is a powerful nucleoside analogue with potent antiviral properties used to combat infectious viruses such as influenza and hepatitis B that replicate through polymerase activity. Additionally, this incredible compound has been extensively researched for its cytotoxic potential against multidrug-resistant cancer cells, offering a new frontier for cancer treatment. With its precise targeting and potent activity, 1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside is a promising treatment option for a range of viral and cancerous diseases. Synonyms: 1-O-Acetyl-3,5-di-O-benzoyl-2-deoxy-2-fluoro-b-D-ribofuranoside; SCHEMBL5974836. CAS No. 149623-91-6. Molecular formula: C21H19FO7. Mole weight: 402.4. | |
| 2-[1-(4,4-Difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide | 2-[1-(4,4-Difluorocyclohexyl)-4-piperidinyl]-6-fluoro-2,3-dihydro-3-oxo-1H-isoindole-4-carboxamide is a nuclear protein poly(ADP-ribose) polymerase-1 (PARP-1) inhibitor. PARP-1 is involved with the signaling and repair of DNA and a target in oncology. Group: Biochemicals. Grades: Highly Purified. CAS No. 1262417-51-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C20H24F3N3O2, Molecular Weight: 395.42. US Biological Life Sciences. | Worldwide |
| 2,2'-Anhydro-L-uridine | 2,2'-Anhydro-L-uridine is a nucleoside analogue in the realm of biomedicine. It effects an inhibition of select thermophilic DNA polymerases, thereby carving a niche in research focused on antiviral and anticancer drugs. Synonyms: 2,2'-Anhydro-L-uridine; 31501-46-9; (2S,4S,5S,6R)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one; SCHEMBL14208937; DTXSID30446477; (2S,4S,5S,6R)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.0,dodeca-8,11-dien-10-one. Grades: 98%. CAS No. 31501-46-9. Molecular formula: C9H10N2O5. Mole weight: 226.19. | |
| 2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine | 2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine, a highly effective antiviral compound, demonstrates remarkable capabilities in combating viral infections. By impeding viral RNA replication and selectively targeting the viral polymerase, it exhibits an extensive range of activity against diverse viruses such as influenza and herpesvirus. Synonyms: 2',3',5'-Tri-O-benzoyl-2'-β-C-methyl-5-fluorouridine. Grades: ≥95%. CAS No. 2072145-49-2. Molecular formula: C31H25FN2O9. Mole weight: 588.54. | |
| 2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyluridine | 2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyluridine is a highly modified nucleoside characterized by its frequent use in RNA synthesis. Acting as a substrate for RNA polymerases, its presence ensures the efficient addition of other nucleotides, ultimately leading to the formation of RNA target sequences. This unique compound also has the added benefit of offering insight into the effects of nucleoside modifications on RNA's biological structure and function. Synonyms: 2',3',5'-Tris-O-[(1,1-dimethylethyl)dimethylsilyl]-4'-C-(hydroxymethyl)-Uridine; 1-{2,3-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-α-L-lyxofuranosyl}-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 232588-97-5. Molecular formula: C28H56N2O7Si3. Mole weight: 617.01. | |
| 2',3',6'-TBnz-Guo | 2',3',6'-TBnz-Guo, a nucleoside analogue, serves as a therapeutic agent against several viral infections, such as hepatitis B and C. Notably, this compound hinders viral replication whilst curbing inflammation, owing to an active inhibition of viral polymerase enzyme. Furthermore, 2',3',6'-TBnz-Guo is a versatile research tool employed to uncover intricate mechanisms of antiviral agents and nucleotide chemistry. CAS No. 66048-63-1. Molecular formula: C31H26N6O8. Mole weight: 696.6. | |
| 2,3-DCPE hydrochloride | 2,3-DCPE hydrochloride is a compound that selectively induces apoptosis and downregulates Bcl-XL protein expression in multiple human cancer cells versus normal cells in vitro. It also specifically cleaves caspase-8, caspase-3, caspase-9, and poly(ADP-ribose) polymerase in cancer cells. Uses: Antitumor agent. Synonyms: 2,3-DCPE HCl; 2-((3-(2,3-Dichlorophenoxy)propyl)amino)ethan-1-ol hydrochloride. Grades: ≥99% by HPLC. CAS No. 1009555-55-8. Molecular formula: C11H16Cl3NO2. Mole weight: 300.61. | |
| 2,?3-?Diaminobenzamide Dihydrochloride | 2,?3-?Diaminobenzamide Dihydrochloride can be used in synthesis and evaluation of (heteroaryl phenyl ) benzimidazolecarboxami de s as orally efficacious poly(ADP-ribose) polymerase-1 inhibitors and anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 266993-72-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H9N3O; 2(HCl), Molecular Weight: 151.1723646. US Biological Life Sciences. | Worldwide |
| 2',3'-Dideoxy-2',2'-difluorocytidine | 2',3'-Dideoxy-2',2'-difluorocytidinea potent antiviral agentfinds clinical application in the management of HIV and hepatitis B virus (HBV) infections. By impeding the reverse transcriptase enzyme, it effectively hampers viral replication. This nucleoside analogue demonstrates a remarkable affinity for viral polymerases, ensuring minimal toxicity to host cells. Synonyms: 4-amino-1-((2R,5S)-3,3-difluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. CAS No. 124708-94-7. Molecular formula: C9H11F2N3O3. Mole weight: 247.20. | |
| 2',3'-Dideoxyadenosine-5'-monothiophosphate | 2',3'-Dideoxyadenosine-5'-monothiophosphate is a vital compound used in the biomedicine industry. Acting as a nucleotide analogue, it inhibits viral reverse transcriptase and DNA polymerase, thus displaying antiviral activity against various retroviruses. Synonyms: 2',3'-Dideoxyadenosine-5'-monothiophosphate; 1266500-93-9; SCHEMBL20028990; SCHEMBL21636992; SCHEMBL22990586. Grades: ≥ 95% (HPLC). CAS No. 1266500-93-9. Molecular formula: C10H14N5O4PS. Mole weight: 331.29. | |
| 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) | 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a biomedically significant reagent used to investigate the intricate mechanisms of DNA synthesis and repair. As a non-hydrolyzable analog of adenosine triphosphate (ATP), it is implicated in inhibiting the activity of reverse transcriptase - a vital aspect of HIV/AIDS treatment. With its remarkable affinity and specificity towards RNA polymerase and other enzymes central to DNA metabolism, this powerful tool is a prized asset for researchers in the biomedical field. Synonyms: Alpha Thiol ddATP; 1-Thio-ddATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O10P3S. Mole weight: 491.20. | |
| 2',3'-Dideoxyadenosine 5'-Triphosphate | ddATP is an inhibitor of reverse transcriptases from retroviruses, such as HIV-1 and visna (Kis = 20 and 37 nM, respectively). ddATP is commonly used to terminate chain extension produced by the Taq polymerase for its competitive effect with dATP in cells. Uses: Ddatp is an inhibitor of reverse transcriptases from retroviruses. Synonyms: [[(2S,5R)-5-(6-aminopurin-9-yl)-2-oxolanyl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; [[(2S,5R)-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Grades: ≥ 98 % by HPLC. CAS No. 24027-80-3. Molecular formula: C10H16N5O11P3. Mole weight: 475.18. | |
| 2',3'-Dideoxyadenosine-5'-Triphosphate | 2',3'-Dideoxyadenosine-5'-Triphosphate is a nucleoside triphosphate analogue commonly used in biomedical research to study polymerases and reverse transcriptases. It can be incorporated into DNA or RNA strands, resulting in chain termination and inhibition of replication. Additionally, 2',3'-Dideoxyadenosine-5'-Triphosphate has potential antiviral properties and has been studied as a treatment for HIV and hepatitis B. Synonyms: ddATP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O11P3. Mole weight: 475.10. | |
| 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt | 2',3'-Dideoxyadenosine-5'-triphosphate lithium salt, a nucleoside analogue renowned for inhibiting DNA polymerase, has found widespread use in treatments for HIV and research surrounding neurological disorders, whilst also serving as a staple in studying DNA sequencing and a variety of genetic diseases. Synonyms: ddATP. Grades: ≥ 95% (HPLC). CAS No. 93939-70-9. Molecular formula: C10H12N5O11P3·3Li. Mole weight: 498.91. | |
| 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate) | 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate), a potent nucleotide analog, serves as a promising biomedical product towards combatting multiple viral infections such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Not only does this chain-terminating inhibitor effectively target viral reverse transcriptase and RNA polymerase, but it also displays promising results in cancer treatment and cell signaling research. Its potential to revolutionize antiviral therapy warrants further exploration. Synonyms: Alpha Thiol ddGTP; 1-Thio-ddGTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O11P3S. Mole weight: 507.25. | |
| 2',3'-Dideoxyinosine-5'-Triphosphate | 2',3'-Dideoxyinosine-5'-Triphosphate, a nucleoside analogue predominantly employed for investigating facets of DNA and RNA replication, impeding reverse transcriptases, and regulating DNA polymerases, exhibits immense potential as an efficient therapeutic agent against a host of viral infections, such as HIV. Synonyms: ddITP; Didanosine triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N4O12P3. Mole weight: 476.10. | |
| 2',3'-Di-O-isopropylidene-5-hydroxymethyluridine | 2',3'-Di-O-isopropylidene-5-hydroxymethyluridine, a nucleoside analogue, has been widely utilized in biomedical research as a vital and consequential substrate for RNA polymerase. The paramountcy of this analog has been accentuated by its incumbent placement in oligonucleotides wherein its impact on RNA structure and function has been meticulously studied. The prospects of this compound have been extolled as it has been observed to proffer inhibitory effects on select viral strains, thereby enhancing its application in the treatment of viral diseases. Synonyms: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)uridine; 2',3'-O-Isopropylidene-5-hydroxymethyluridine; 5-Hydroxymethyl-2',3'-(di-O-isopropylidene)uridine; 5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)uridine; 5-(Hydroxymethyl)-2',3'-O-isopropylideneuridine. Grades: ≥95%. CAS No. 3816-77-1. Molecular formula: C13H18N2O7. Mole weight: 314.29. | |
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