Polymyxin Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
Polymyxin B Quick inquiry Where to buy Suppliers range | Polymyxin B is an antibacterial peptide isolated from Bacillus polymyxa. It has activity against gram-negative bacteria and fungi. Synonyms: Unk-Dab-Thr-Dab-Dab(1)-D-Dab-D-Phe-Leu-Dab-Dab-Thr-(1). Grades: >97%. Molecular formula: C59H108N16O13. Mole weight: 1249.59. | |
Polymyxin B Quick inquiry Where to buy Suppliers range | Polymyxin B. Uses: Antimicrobial Peptides. Product ID: AF083. | |
Polymyxin B1 Quick inquiry Where to buy Suppliers range | Polymyxin B1. Group: Biochemicals. Alternative Names: N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide. Grades: Highly Purified. CAS No. 4135-11-9. Pack Sizes: 2.5mg. Molecular Formula: C56H98N16O13, Molecular Weight: 1203.48. US Biological Life Sciences. | Worldwide |
Polymyxin B1 Quick inquiry Where to buy Suppliers range | Polymyxin B1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine}; polymycin B. Grades: ≥95%. CAS No. 4135-11-9. Molecular formula: C56H98N16O13. Mole weight: 1203.47. | |
Polymyxin B1 Quick inquiry Where to buy Suppliers range | Polymyxin B1. Uses: For analytical and research use. Group: British Pharmacopoeia; Pharmacopoeial Standards. CAS No. 1404-26-8. Pack Sizes: 100MG. Mole weight: 1203.5. Catalog: APS1404268. Format: Neat. Product Type: API. Shipping: Room Temperature. | |
Polymyxin B1 Sulfate Quick inquiry Where to buy Suppliers range | It is produced by the strain of Pseudomonas sp. It is one of the polypeptide fractions in polymyxin B sulfate. Polymyxin B1 is an antibacterial compound. It has a high volume of distribution and longer elimination half-life in patients with multidrug-resistant gram-negative bacterial infection. Synonyms: Polymyxin B1 sulfate salt (1:1); N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide sulfate (1:1). Grades: >90.0%. CAS No. 108965-61-3. Molecular formula: C56H98N16O13.H2SO4. Mole weight: 1301.55. | |
Polymyxin B2 Quick inquiry Where to buy Suppliers range | Polymyxin B2 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Grades: >98%. CAS No. 34503-87-2. Molecular formula: C55H96N16O13. Mole weight: 1189.45. | |
Polymyxin B3 sulfate Quick inquiry Where to buy Suppliers range | It is produced by the strain of Pseudomonas sp. Polymyxin B3 sulfate is an individual fraction found in the antibiotic mixture polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grades: ≥90.0% by HPLC. Molecular formula: C55H96N16O13.xH2O4S. Mole weight: 1189.45 (free base). | |
Polymyxin B6 sulfate Quick inquiry Where to buy Suppliers range | It is produced by the strain of Bacillus Polymyxa. Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grades: >90.0%. Molecular formula: C56H98N16O14.xH2SO4. Mole weight: 1219.47 (free base). | |
Polymyxin B nonapeptide Quick inquiry Where to buy Suppliers range | Polymyxin B nonapeptide is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing th. Uses: Peptide Inhibitors. CAS No. 86408-36-8. Product ID: R1623. | |
Polymyxin B nonapeptide Quick inquiry Where to buy Suppliers range | Polymyxin B nonapeptide interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: Polymyxin B Cyclononapeptide; Polymyxin B1, 1-De(N2-(6-Methyl-1-Oxooctyl)-L-2,4-Diaminobutanoic Acid)-; PMBN; T-Dab-Dab-Dab-Dab-d-FL-Dab-Dab-T (Lactam: Dab3-Thr9); N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); Nα-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-). Grades: ≥95%. CAS No. 86408-36-8. Molecular formula: C43H74N14O11. Mole weight: 963.13. | |
Polymyxin B nonapeptide acetate Quick inquiry Where to buy Suppliers range | Polymyxin B nonapeptide acetate is a cationic cyclic peptide that interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: H-Thr-Dab-Dab-Dab-D-Phe-Leu-Dab-Dab-Thr.CH3CO2H (Disulfide bridge: Cys3-Cys9); Polymyxin B1, 1-de[N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid]-, acetate; 2-10-Polymyxin B1 acetate. Grades: ≥95%. Molecular formula: C45H78N14O13. Mole weight: 1023.19. | |
Polymyxin b nonapeptide hydrochloride Quick inquiry Where to buy Suppliers range | solid. Group: Main Products. Alternative Names: POLYMYXIN B NONAPEPTIDE HYDROCHLORIDE; polymyxinbnonapeptide; N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-Thr-); Nα -(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); PMBN; sPMBN. Grades: 96%. CAS No. 86408-36-8. Molecular formula: C111H194N32O26. Mole weight: 2392.93. IUPAC Name: (2S,3R)-2-amino-N-[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-15-benzyl-3-[(1R)-1-hydroxyethyl]-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]-3-hydroxybutanamide. Exact Mass: 962.56600. Boiling Point: 1456.2ºC at 760 mmHg. Flash Point: 834.5ºC. Density: 1.32g/cm3. SMILES: CC (C)CC1C (=O)NC (C (=O)NC (C (=O)NC (C (=O)NCCC (C (=O)NC (C (=O)NC (C (=O)N1)CC2=CC=CC=C2)CCN)NC (=O)C (CCN)NC (=O)C (C (C)O)N)C (C)O)CCN)CCN. InChIKey: PYHYGIPVYYRJHU-QWDNBKTCSA-N. | |
Polymyxin B nonapeptide TFA Quick inquiry Where to buy Suppliers range | Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. CAS No. 2220175-42-6. Molecular formula: C53H79F15N14O21. Mole weight: 1533.25. | |
Polymyxin B (PMB) Quick inquiry Where to buy Suppliers range | The peptide Polymyxin B (PMB) is a cyclic amphipathic peptide antibiotic that binds to endotoxins (lipopolysaccharide, LPS). Binding of PMB to LPS results in neutralization of LPS of gram-negative bacteria. For the study of PMB-LPS interactions PMB conjugates proved to be superior to the application of anti-PMB antibodies. PMB conjugates are useful general probes to detect or measure lipid A and LPS of various species using simple methods. These conjugates are also useful for staining of bacteria. The conjugates obviate the need for many specific antisera. Furthermore PMB conjugates are useful tools in investigations of LPS binding protein (LBP) and bactericidal permeability increasing protein (BPI) interactions with LPS. PMB conjugates are useful probes for endotoxin research. Group: Biochemicals. Grades: Purified. Pack Sizes: 10KU. US Biological Life Sciences. | Worldwide |
Polymyxin B (PMB) (Biotin) Quick inquiry Where to buy Suppliers range | The peptide Polymyxin B (PMB) is a cyclic amphipathic peptide antibiotic that binds to endotoxins (lipopolysaccharide, LPS). Binding of PMB to LPS results in neutralization of LPS of gram-negative bacteria. For the study of PMB-LPS interactions PMB conjugates proved to be superior to the application of anti-PMB antibodies. PMB conjugates are useful general probes to detect or measure lipid A and LPS of various species using simple methods. These conjugates are also useful for staining of bacteria. The conjugates obviate the need for many specific antisera. Furthermore PMB conjugates are useful tools in investigations of LPS binding protein (LBP) and bactericidal permeability increasing protein (BPI) interactions with LPS. In conclusion, PMB conjugates are useful probes for endotoxin research. Group: Biochemicals. Grades: Purified. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
Polymyxin B (PMB) (HRP) Quick inquiry Where to buy Suppliers range | The peptide Polymyxin B (PMB) is a cyclic amphipathic peptide antibiotic that binds to endotoxins (lipopolysaccharide, LPS). Binding of PMB to LPS results in neutralization of LPS of gram-negative bacteria. For the study of PMB-LPS interactions PMB conjugates proved to be superior to the application of anti-PMB antibodies. PMB conjugates are useful general probes to detect or measure lipid A and LPS of various species using simple methods. These conjugates are also useful for staining of bacteria. The conjugates obviate the need for many specific antisera. Furthermore PMB conjugates are useful tools in investigations of LPS binding protein (LBP) and bactericidal permeability increasing protein (BPI) interactions with LPS. In conclusion, PMB conjugates are useful probes for endotoxin research. Group: Biochemicals. Grades: Purified. Pack Sizes: 200ul. US Biological Life Sciences. | Worldwide |
Polymyxin B sulfate Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C55H96N16O13 · 2H2SO4. CAS No. 1405-20-5. Prepack ID 59662126-1g. Molecular Weight 1385.61. See USA prepack pricing. | |
Polymyxin B sulfate Quick inquiry Where to buy Suppliers range | 5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C55H96N16O13 · 2H2SO4. CAS No. 1405-20-5. Prepack ID 59662126-5g. Molecular Weight 1385.61. See USA prepack pricing. | |
Polymyxin B Sulfate Quick inquiry Where to buy Suppliers range | Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixture of Polymyxin B1 and B2 sulfate. Group: Biochemicals. Alternative Names: N- [3-Amino-1- [ [1- [ [3-amino-1- [ [6, 9, 18-tris (2-aminoethyl) -15-benzyl-3- (1-hydroxyethyl) -12- (2-methylpropyl) -2, 5, 8, 11, 14, 17, 20-heptaoxo-1, 4, 7, 10, 13, 16, 19-heptazacyclotricos-21-yl] carbamoyl] propyl] carbamoyl] -2-hydroxy-propyl] carbamoyl] propyl] -6-methyl-octanamide Sulfuric Acid. Grades: Highly Purified. CAS No. 1405-20-5. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
POLYMYXIN B SULFATE Quick inquiry Where to buy Suppliers range | POLYMYXIN B SULFATE. CAS No. 1405-20-5. Ebrator Biochemicals provides scientists around the global scientific community with a wide range of high purity Life Science products & Fine Chemicals. Categories: Polymyxin B Sulfate. | |
Polymyxin B Sulfate ≥6500 IU/mg Quick inquiry Where to buy Suppliers range | Polymyxin B Sulfate ≥6500 IU/mg. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5MU, 25MU, 100MU. US Biological Life Sciences. | Worldwide |
Polymyxin b sulfate salt Quick inquiry Where to buy Suppliers range | Polymyxin b sulfate salt. Group: Main Products. Alternative Names: PolymyxineBsulfate; MASTIMYXIN; POLYMYXIN B; POLYMYXIN B (PMB); POLYMIXIN B SULFATE; Polymyxin B Sulfate; APPLISORB; PolymyxinBSulfate(sterile,non-sterile); AEROSPORIN; POLYMIXIN B SULPHATE; MYP SUPPLEMENT. Grades: USP/EP. CAS No. 1405-20-5. Product ID: ACM1405205. Molecular formula: C55H96N16O13·2H2SO4. Mole weight: 1385.61. IUPAC Name: Polymyxin B sulfate. Appearance: White crystalline powder. Boiling Point: 1651ºC at 760 mmHg. Flash Point: 952.3ºC. | |
Polymyxin B Sulfate USP (Bacillus polymyxa prazmowski migula, Aerosporin) Quick inquiry Where to buy Suppliers range | Antibiotic which inhibits PKC via bacterial membrane binding mechanism. Effective against gram negative bacteria. Polymyxins bind to the cell membrane and alter its structure making it more permeable. The resulting water uptake leads to cell death. They are cationic, basic proteins that act like detergents (surfactants}. Side effects include neurotoxicity and acute renal tubular necrosis. it is commonly used in the topical first aid preparation Neosporin. Polymyxin B belongs to a family of polypeptides with attached fatty acid, acting as a cationic detergent at physiological pH, both hydrophilic and hydrophobic properties. Polymyxin B is bactericidal for gram-negative, and has little to no effect on gram-positive since cell wall is too thick to permit access to membrane. Group: Biochemicals. Alternative Names: Bacillus polymyxa prazmowski migula, Aerosporin. Grades: Cell Culture Grade. CAS No. 1405-20-5. Pack Sizes: 10MU, 50MU, 100MU. US Biological Life Sciences. | Worldwide |
Polymyxin D1 Quick inquiry Where to buy Suppliers range | Polymyxin D1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. CAS No. 10072-50-1. Molecular formula: C50H93N15O15. Mole weight: 1144.36. | |
Polymyxin D2 Quick inquiry Where to buy Suppliers range | Polymyxin D2 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Grades: >98%. CAS No. 34167-45-8. Molecular formula: C49H91N15O15. Mole weight: 1130.33. | |
Polymyxin E1 Sulfate Quick inquiry Where to buy Suppliers range | It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E1 Sulfate is sulfate salt form of Polymyxin E1, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin A Sulfate; Polymixin E1 Sulfate salt; Colistin IV Sulfate; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide Sulfate. Grades: ≥90.0% by HPLC. Molecular formula: C53H100N16O13.xH2SO4. Mole weight: 1169.46 (free base). | |
Polymyxin E2 Sulfate Quick inquiry Where to buy Suppliers range | It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10?4)-Lactam Sulfate Salt. Grades: ≥90.0% by HPLC. CAS No. 1338055-88-1. Molecular formula: C52H98N16O13.xH2SO4. Mole weight: 1155.43 (free base). | |
Polymyxin Ile-B1 Sulfate Quick inquiry Where to buy Suppliers range | It is produced by the strain of Pseudomonas Sp. It is one of the individual polypeptide components in polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Synonyms: Polymyxin B1-I sulfate; Polymyxin II Sulfate; Polymyxin B1 Isoleucine sulfate. Grades: ≥90.0%. Molecular formula: C56H98N16O13.xH2O4S. Mole weight: 1203.47 (free base). | |
Polymyxin M Quick inquiry Where to buy Suppliers range | Polymyxin M is a cyclic peptide antibiotic produced by Bacillus polymyxa var. Ross. Synonyms: mattacin. Grades: 95%. CAS No. 6683-17-6. Molecular formula: C51H96N16O14. Mole weight: 1157.40. | |
Polymyxin S1 Quick inquiry Where to buy Suppliers range | Polymyxin S1 is a cyclic peptide antibiotic of Bacillus polymyxa RS-6. Activity against gram-positive bacteria. Synonyms: Polymyxin D1, 6-D-phenylalanine. CAS No. 63700-38-9. Molecular formula: C53H91N15O15. Mole weight: 1178.38. | |
Polymyxin T1 Quick inquiry Where to buy Suppliers range | Polymyxin T1 is a cyclic peptide antibiotic of Bacillus polymyxa E-12. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: Polymyxin B1, 10-L-leucine. CAS No. 63700-39-0. Molecular formula: C58H102N16O12. Mole weight: 1215.53. | |
1,2-Dihexadecanoyl-rac-glycero-3-phospho-rac-(1-glycerol) Ammonium Salt Quick inquiry Where to buy Suppliers range | 1,2-Dihexadecanoyl-rac-glycero-3-phospho-rac-(1-glycerol) shows strong interaction with the cationic antibiotic polymyxin B. Group: Biochemicals. Grades: Highly Purified. CAS No. 73548-70-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C38H78NO10P, Molecular Weight: 740. US Biological Life Sciences. | Worldwide |
Colistin Quick inquiry Where to buy Suppliers range | It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram negative infections including pneumonia. Synonyms: Polymyxin E; Colobreathe; Promixin; Colimycin M; Belcomycin; Colymycin; Torazin; N-[(1S)-3-amino-1-[[(1S,2R)-1-[[(1S)-3-amino-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide. Grades: >95% by HPLC. CAS No. 1066-17-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. | |
Colistin A Quick inquiry Where to buy Suppliers range | Colistin A is an antibiotic produced by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria. Synonyms: Polymixin E1. Grades: ≥ 95%. CAS No. 7722-44-3. Molecular formula: C53H100N16O13. Mole weight: 1169.48. | |
Colistin B Quick inquiry Where to buy Suppliers range | It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin B is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Polymyxin E2; Colistin b; 4,10-anhydro[N-(6-methylheptanoyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine]. Grades: ≥ 95%. CAS No. 7239-48-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. | |
Colistin sodium methanesulfonate Quick inquiry Where to buy Suppliers range | A unique sparingly soluble cyclic polypeptide antibiotic known as a polymyxin. It has a bactericidal effect on bacteria by targeting the cell membrane and modifying its permeability. CAS No. 8068-28-8. Molecular formula: C58H105N16Na5O28S5. Mole weight: 1749.8. | |
Colistin sulfate Quick inquiry Where to buy Suppliers range | Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa. Synonyms: Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin. Grades: ≥95%. CAS No. 1264-72-8. Molecular formula: Colistin A: C53H100N16O13; Colistin B: C52H98N16O13. Mole weight: Colistin A: 1169.46; Colistin B: 1155.43. | |
Colistin Sulfate (Mixture of A and B compound) Quick inquiry Where to buy Suppliers range | Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistin A and B.Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic. Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter.[1] New Delhi metallo- β-Lactamase multidrug-resistant Enterobacteriaceae have also shown susceptibility to Colistin.[2]Colistin is polycationic and has both hydrophilic and lipophilic moieties. These poly-cationic regions interact with the bacterial outer membrane, by displacing bacterial counter ions in the lipopolysaccharide. Hydrophobic / hydrophillic regions interact with the cytoplasmic membrane just like a detergent, solubilizing the membrane in an aqueous environment. This effect is bactericidal even in an isosmolaric environment.Resistance to colistin is currently rare, but is described. At present there is no agreement about how to look for colistin resistance. The Société Française de Microbiologie uses a cut off of 2 mg/l, whereas the British Society for Antimicrobial Chemotherapy sets a cutoff of 4 mg/l or less as sensitive, and 8 mg/ml or more as resistant. There are not currently any US standards for measuring colistin sensitivity. Exceptional (inherently colistin resistant) Gram-negative bacteria: BrucellaBurkholderia cepaciaChryseobacteriu m indologen esEdwardsiel laElizabethkingia meningosepticaFrancise lla tularensis spp.Gram-negative cocciHelicobacter pyloriMoraxella catarrhalisNeisseria gonorrheae and Neisseria meningitidisProteusPro vide nciaSerratiaSome strains of Stenotrophomonas maltophilia[18]Gram-negative organisms with variable resistance to colistin: AeromonasVib rioPrevotellaFusobacte rium . Group: Biochemicals. Alternative Names: Polymyxin E. sulfate; Belcomycine; Colomycin. Grades: Highly Purified. CAS No. 1264-72-8. Pack Sizes: 250mg, 1g, 5g, 10g. Molecular Formula: x(C??H???N??O??)? + x(C ??H??N??O??)B.xH?, Molecular Weight: 1169.46. US Biological Life Sciences. | Worldwide |
Cyclogregatin Quick inquiry Where to buy Suppliers range | It is produced by the strain of Aspergillus panamensis. It has anti-bacterial and fungal activity, but its antibacterial and fungal activity is lower than polymyxin A. It inhibits airy ascites carcinoma with MIC of 10 μg/mL (Gregatin A is 2 μg/mL). Synonyms: 4H-Furo(2,3-b)pyran-3,4(2H)-dione, 2-(1,3-hexadienyl)-5,6-dihydro-2,6-dimethyl-. CAS No. 120167-25-1. Molecular formula: C15H18O4. Mole weight: 262.30. | |
SPR-741 Quick inquiry Where to buy Suppliers range | SPR741 is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 increases the permeability of the outer membrane of Gram-negative bacteria and is used to treat severe Gram-negative bacterial infections. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741. Uses: Peptide Inhibitors. CAS No. 1179330-52-9. Product ID: R1844. | |
SPR741 Quick inquiry Where to buy Suppliers range | SPR741 is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA. Synonyms: NAB741. Grades: >98%. CAS No. 1179330-52-9. Molecular formula: C44H73N13O13. Mole weight: 992.13. |