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Polymyxin B Polymyxin B is an antibacterial peptide isolated from Bacillus polymyxa. It has activity against gram-negative bacteria and fungi. Synonyms: Unk-Dab-Thr-Dab-Dab(1)-D-Dab-D-Phe-Leu-Dab-Dab-Thr-(1). Grades: >97%. Molecular formula: C59H108N16O13. Mole weight: 1249.59. BOC Sciences 4
Polymyxin B Polymyxin B is an antibiotic. Polymyxin B inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B neutralizes the effect of endotoxin. Polymyxin B induces bacterial death by increasing its permeability. Polymyxin B is used in endotoxemia research [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1404-26-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-149179. MedChemExpress MCE
Polymyxin B Polymyxin B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1404-26-8. Molecular Formula: C56H98N16O13/C55H96N16O13. Mole Weight: 1203.5/1189.47. Catalog: APB1404268. Alfa Chemistry Analytical Products
Polymyxin B1 Polymyxin B1. Group: Biochemicals. Alternative Names: N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide. Grades: Highly Purified. CAS No. 4135-11-9. Pack Sizes: 2.5mg. Molecular Formula: C56H98N16O13, Molecular Weight: 1203.48. US Biological Life Sciences. USBiological 3
Worldwide
Polymyxin B1 Polymyxin B1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine}; polymycin B. Grades: ≥95%. CAS No. 4135-11-9. Molecular formula: C56H98N16O13. Mole weight: 1203.47. BOC Sciences 5
Polymyxin B1 Polymyxin B1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4135-11-9. Molecular Formula: C56H98N16O13. Mole Weight: 1203.5. Catalog: APB4135119. Alfa Chemistry Analytical Products 3
Polymyxin B1A Polymyxin B1A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 811435-10-6. Molecular Formula: C56H98N16O13. Mole Weight: 1203.5. Catalog: APB811435106. Alfa Chemistry Analytical Products 3
Polymyxin B1 Sulfate It is produced by the strain of Pseudomonas sp. It is one of the polypeptide fractions in polymyxin B sulfate. Polymyxin B1 is an antibacterial compound. It has a high volume of distribution and longer elimination half-life in patients with multidrug-resistant gram-negative bacterial infection. Synonyms: Polymyxin B1 sulfate salt (1:1); N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide sulfate (1:1). Grades: >90.0%. CAS No. 108965-61-3. Molecular formula: C56H98N16O13.H2SO4. Mole weight: 1301.55. BOC Sciences 5
Polymyxin B2 Polymyxin B2 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Grades: >98%. CAS No. 34503-87-2. Molecular formula: C55H96N16O13. Mole weight: 1189.45. BOC Sciences 5
Polymyxin B2 Polymyxin B2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 34503-87-2. Molecular Formula: C55H96N16O13. Mole Weight: 1189.47. Catalog: APB34503872. Alfa Chemistry Analytical Products 2
Polymyxin B3 Polymyxin B3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71140-58-4. Molecular Formula: C55H96N16O13. Mole Weight: 1189.47. Catalog: APB71140584. Alfa Chemistry Analytical Products 2
Polymyxin B3 sulfate It is produced by the strain of Pseudomonas sp. Polymyxin B3 sulfate is an individual fraction found in the antibiotic mixture polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grades: ≥90.0% by HPLC. Molecular formula: C55H96N16O13.xH2O4S. Mole weight: 1189.45 (free base). BOC Sciences 5
Polymyxin B6 sulfate It is produced by the strain of Bacillus Polymyxa. Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grades: >90.0%. Molecular formula: C56H98N16O14.xH2SO4. Mole weight: 1219.47 (free base). BOC Sciences 5
Polymyxin B nonapeptide Polymyxin B nonapeptide interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: Polymyxin B Cyclononapeptide; Polymyxin B1, 1-De(N2-(6-Methyl-1-Oxooctyl)-L-2,4-Diaminobutanoic Acid)-; PMBN; T-Dab-Dab-Dab-Dab-d-FL-Dab-Dab-T (Lactam: Dab3-Thr9); N2-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-); Nα-(L-Thr-L-A2bu-)Cyclo(L-A2bu*-L-A2bu-D-Phe-L-Leu-L-A2bu-L-A2bu-L-Thr-). Grades: ≥95%. CAS No. 86408-36-8. Molecular formula: C43H74N14O11. Mole weight: 963.13. BOC Sciences 9
Polymyxin B nonapeptide acetate Polymyxin B nonapeptide acetate is a cationic cyclic peptide that interacts with the outer membrane of gram-negative bacteria to increase the permeability of the membrane by promoting hydrophobic diffusion. Synonyms: H-Thr-Dab-Dab-Dab-D-Phe-Leu-Dab-Dab-Thr.CH3CO2H (Disulfide bridge: Cys3-Cys9); Polymyxin B1, 1-de[N2-(6-methyl-1-oxooctyl)-L-2,4-diaminobutanoic acid]-, acetate; 2-10-Polymyxin B1 acetate. Grades: ≥95%. Molecular formula: C45H78N14O13. Mole weight: 1023.19. BOC Sciences 6
Polymyxin B nonapeptide TFA Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. CAS No. 2220175-42-6. Molecular formula: C53H79F15N14O21. Mole weight: 1533.25. BOC Sciences 6
Polymyxin B (PMB) The peptide Polymyxin B (PMB) is a cyclic amphipathic peptide antibiotic that binds to endotoxins (lipopolysaccharide, LPS). Binding of PMB to LPS results in neutralization of LPS of gram-negative bacteria. For the study of PMB-LPS interactions PMB conjugates proved to be superior to the application of anti-PMB antibodies. PMB conjugates are useful general probes to detect or measure lipid A and LPS of various species using simple methods. These conjugates are also useful for staining of bacteria. The conjugates obviate the need for many specific antisera. Furthermore PMB conjugates are useful tools in investigations of LPS binding protein (LBP) and bactericidal permeability increasing protein (BPI) interactions with LPS. PMB conjugates are useful probes for endotoxin research. Group: Biochemicals. Grades: Purified. Pack Sizes: 10KU. US Biological Life Sciences. USBiological 3
Worldwide
Polymyxin B (PMB) (Biotin) The peptide Polymyxin B (PMB) is a cyclic amphipathic peptide antibiotic that binds to endotoxins (lipopolysaccharide, LPS). Binding of PMB to LPS results in neutralization of LPS of gram-negative bacteria. For the study of PMB-LPS interactions PMB conjugates proved to be superior to the application of anti-PMB antibodies. PMB conjugates are useful general probes to detect or measure lipid A and LPS of various species using simple methods. These conjugates are also useful for staining of bacteria. The conjugates obviate the need for many specific antisera. Furthermore PMB conjugates are useful tools in investigations of LPS binding protein (LBP) and bactericidal permeability increasing protein (BPI) interactions with LPS. In conclusion, PMB conjugates are useful probes for endotoxin research. Group: Biochemicals. Grades: Purified. Pack Sizes: 200ul. US Biological Life Sciences. USBiological 1
Worldwide
Polymyxin B (PMB) (HRP) The peptide Polymyxin B (PMB) is a cyclic amphipathic peptide antibiotic that binds to endotoxins (lipopolysaccharide, LPS). Binding of PMB to LPS results in neutralization of LPS of gram-negative bacteria. For the study of PMB-LPS interactions PMB conjugates proved to be superior to the application of anti-PMB antibodies. PMB conjugates are useful general probes to detect or measure lipid A and LPS of various species using simple methods. These conjugates are also useful for staining of bacteria. The conjugates obviate the need for many specific antisera. Furthermore PMB conjugates are useful tools in investigations of LPS binding protein (LBP) and bactericidal permeability increasing protein (BPI) interactions with LPS. In conclusion, PMB conjugates are useful probes for endotoxin research. Group: Biochemicals. Grades: Purified. Pack Sizes: 200ul. US Biological Life Sciences. USBiological 1
Worldwide
Polymyxin B sulfate 1g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C55H96N16O13 · 2H2SO4. CAS No. 1405-20-5. Prepack ID 59662126-1g. Molecular Weight 1385.61. See USA prepack pricing. Molekula Americas
Polymyxin B sulfate 5g Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C55H96N16O13 · 2H2SO4. CAS No. 1405-20-5. Prepack ID 59662126-5g. Molecular Weight 1385.61. See USA prepack pricing. Molekula Americas
Polymyxin B Sulfate Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixture of Polymyxin B1 and B2 sulfate. Group: Biochemicals. Alternative Names: N- [3-Amino-1- [ [1- [ [3-amino-1- [ [6, 9, 18-tris (2-aminoethyl) -15-benzyl-3- (1-hydroxyethyl) -12- (2-methylpropyl) -2, 5, 8, 11, 14, 17, 20-heptaoxo-1, 4, 7, 10, 13, 16, 19-heptazacyclotricos-21-yl] carbamoyl] propyl] carbamoyl] -2-hydroxy-propyl] carbamoyl] propyl] -6-methyl-octanamide Sulfuric Acid. Grades: Highly Purified. CAS No. 1405-20-5. Pack Sizes: 250mg. US Biological Life Sciences. USBiological 2
Worldwide
Polymyxin B Sulfate Polymyxin B Sulfate is a potent antibacterial agent and a relatively toxic antibiotic. Polymyxin B Sulfate also is a antiendotoxin agent. Polymyxin B Sulfate shows endotoxin-neutralizing properties can be used as adjunctive research in gram-negative sepsis. Polymyxin B Sulfate shows antibacterial activities in vitro and in vivo [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 1405-20-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-A0248. MedChemExpress MCE
Polymyxin B Sulfate ≥6500 IU/mg Polymyxin B Sulfate ≥6500 IU/mg. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5MU, 25MU, 100MU. US Biological Life Sciences. USBiological 5
Worldwide
Polymyxin B Sulfate USP (Bacillus polymyxa prazmowski migula, Aerosporin) Antibiotic which inhibits PKC via bacterial membrane binding mechanism. Effective against gram negative bacteria. Polymyxins bind to the cell membrane and alter its structure making it more permeable. The resulting water uptake leads to cell death. They are cationic, basic proteins that act like detergents (surfactants}. Side effects include neurotoxicity and acute renal tubular necrosis. it is commonly used in the topical first aid preparation Neosporin. Polymyxin B belongs to a family of polypeptides with attached fatty acid, acting as a cationic detergent at physiological pH, both hydrophilic and hydrophobic properties. Polymyxin B is bactericidal for gram-negative, and has little to no effect on gram-positive since cell wall is too thick to permit access to membrane. Group: Biochemicals. Alternative Names: Bacillus polymyxa prazmowski migula, Aerosporin. Grades: Cell Culture Grade. CAS No. 1405-20-5. Pack Sizes: 10MU, 50MU, 100MU. US Biological Life Sciences. USBiological 1
Worldwide
Polymyxin D1 Polymyxin D1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. CAS No. 10072-50-1. Molecular formula: C50H93N15O15. Mole weight: 1144.36. BOC Sciences 5
Polymyxin D2 Polymyxin D2 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Grades: >98%. CAS No. 34167-45-8. Molecular formula: C49H91N15O15. Mole weight: 1130.33. BOC Sciences 5
Polymyxin E1 Sulfate It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E1 Sulfate is sulfate salt form of Polymyxin E1, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin A Sulfate; Polymixin E1 Sulfate salt; Colistin IV Sulfate; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide Sulfate. Grades: ≥90.0% by HPLC. Molecular formula: C53H100N16O13.xH2SO4. Mole weight: 1169.46 (free base). BOC Sciences 5
Polymyxin E2 Sulfate It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10?4)-Lactam Sulfate Salt. Grades: ≥90.0% by HPLC. CAS No. 1338055-88-1. Molecular formula: C52H98N16O13.xH2SO4. Mole weight: 1155.43 (free base). BOC Sciences 5
Polymyxin Ile-B1 Sulfate It is produced by the strain of Pseudomonas Sp. It is one of the individual polypeptide components in polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Synonyms: Polymyxin B1-I sulfate; Polymyxin II Sulfate; Polymyxin B1 Isoleucine sulfate. Grades: ≥90.0%. Molecular formula: C56H98N16O13.xH2O4S. Mole weight: 1203.47 (free base). BOC Sciences 5
Polymyxin M Polymyxin M is a cyclic peptide antibiotic produced by Bacillus polymyxa var. Ross. Synonyms: mattacin. Grades: 95%. CAS No. 6683-17-6. Molecular formula: C51H96N16O14. Mole weight: 1157.40. BOC Sciences 6
Polymyxin S1 Polymyxin S1 is a cyclic peptide antibiotic of Bacillus polymyxa RS-6. Activity against gram-positive bacteria. Synonyms: Polymyxin D1, 6-D-phenylalanine. CAS No. 63700-38-9. Molecular formula: C53H91N15O15. Mole weight: 1178.38. BOC Sciences 5
Polymyxin sulfate B Polymyxin sulfate B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1405-20-5. Molecular Formula: C56H100N16O17S. Mole Weight: 1301.56. Catalog: APB1405205. Alfa Chemistry Analytical Products
Polymyxin T1 Polymyxin T1 is a cyclic peptide antibiotic of Bacillus polymyxa E-12. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: Polymyxin B1, 10-L-leucine. CAS No. 63700-39-0. Molecular formula: C58H102N16O12. Mole weight: 1215.53. BOC Sciences 5
Native Pseudomonas sp. Polymyxin Acylase Polymyxin acylase, from Pseudomonas sp. deacylates polymyxin group antibiotics and long-chain fatty acyl groups of proteins. Polymyxin acylase has an affinity for long-chain fatty acyl proteins in human carcinoma cells. Applications: Polymyxin acylase, from pseudomonas sp., is a n-myristoyl cleaving enzyme that has been used to determine the n-myristoyl peptide sequence and may be useful in cancer research since it has antitumor activity against murine and human tumor cells. Group: Enzymes. Synonyms: Polymyxin Acylase; Peptide N-fatty acylase. CAS No. 111174-43-7. Polymyxin Acylase. Activity: > 0.1 units/mg solid. Stability: -20°C. Source: Pseudomonas sp. Polymyxin Acylase; Peptide N-fatty acylase. Cat No: NATE-0611. Creative Enzymes
1,2-Dihexadecanoyl-rac-glycero-3-phospho-rac-(1-glycerol) Ammonium Salt 1,2-Dihexadecanoyl-rac-glycero-3-phospho-rac-(1-glycerol) shows strong interaction with the cationic antibiotic polymyxin B. Group: Biochemicals. Grades: Highly Purified. CAS No. 73548-70-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C38H78NO10P, Molecular Weight: 740. US Biological Life Sciences. USBiological 9
Worldwide
Colistin Colistin (Polymyxin E) is an orally active polypeptide antibiotic. Colistin has excellent activity against various Gram-negative rod-shaped bacteria, including multidrug-resistant Pseudomonas aeruginosa , Acinetobacter baumannii and Klebsiella pneumoniae. Colistin is associated with nephrotoxicity. Colistin can be used for the research of infections caused by Gram-negative bacilli [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Polymyxin E. CAS No. 1066-17-7. Pack Sizes: 1 mg. Product ID: HY-113678. MedChemExpress MCE
Colistin It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin, also known as polymyxin E, is an antibiotic medication used as a last-resort treatment for multidrug-resistant Gram negative infections including pneumonia. Synonyms: Polymyxin E; Colobreathe; Promixin; Colimycin M; Belcomycin; Colymycin; Torazin; N-[(1S)-3-amino-1-[[(1S,2R)-1-[[(1S)-3-amino-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-diisobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-5-methyl-heptanamide. Grades: >95% by HPLC. CAS No. 1066-17-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. BOC Sciences 5
Colistin A Colistin A is an antibiotic produced by certain strains of the bacteria Paenibacillus polymyxa. Colistin is a polymyxin antibiotic and can be used to combat infections caused by problematic gram-negative bacteria. Synonyms: Polymixin E1. Grades: ≥ 95%. CAS No. 7722-44-3. Molecular formula: C53H100N16O13. Mole weight: 1169.48. BOC Sciences 5
Colistin B It is produced by the strain of Bacillus polymyxa var. colistinus and Bac. colistinum Koyama 70-B. It has good anti-gram-negative bacterial activity, but has poor effect on Pseudomonas aeruginosa and Proteus aeruginosa. Colistin B is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Polymyxin E2; Colistin b; 4,10-anhydro[N-(6-methylheptanoyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine]. Grades: ≥ 95%. CAS No. 7239-48-7. Molecular formula: C52H98N16O13. Mole weight: 1155.43. BOC Sciences 5
Colistin sodium methanesulfonate A unique sparingly soluble cyclic polypeptide antibiotic known as a polymyxin. It has a bactericidal effect on bacteria by targeting the cell membrane and modifying its permeability. CAS No. 8068-28-8. Molecular formula: C58H105N16Na5O28S5. Mole weight: 1749.8. BOC Sciences 5
Colistin sulfate Colistin sulfate is a polypeptide antibiotic containing greater than 30 components, with colistin A and colistin B as the major components. It inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Colistin was originally isolated from B. polymyxa. Synonyms: Polymyxin E Complex; Colistin sulfate salt (2:5); Belcomycine; Colomycin. Grades: ≥95%. CAS No. 1264-72-8. Molecular formula: Colistin A: C53H100N16O13; Colistin B: C52H98N16O13. Mole weight: Colistin A: 1169.46; Colistin B: 1155.43. BOC Sciences 5
Colistin sulfate Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: Polymyxin E sulfate. CAS No. 1264-72-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0089. MedChemExpress MCE
Colistin Sulfate (Mixture of A and B compound) Cyclic polypeptide antibiotic produced by Bacillus polymyxa. Complex mixture of at least 30 components, primarily colistin A and B.Colistin (polymyxin E) is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a polypeptide antibiotic. Colistin is a decades-old drug that fell out of favor due to its nephrotoxicity. It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter.[1] New Delhi metallo- β-Lactamase multidrug-resi...ia cepaciaChryseobacteriu m indologen esEdwardsiel laElizabethkingia meningosepticaFrancise lla tularensis spp.Gram-negative cocciHelicobacter pyloriMoraxella catarrhalisNeisseria gonorrheae and Neisseria meningitidisProteusPro vide nciaSerratiaSome strains of Stenotrophomonas maltophilia[18]Gram-negative organisms with variable resistance to colistin: AeromonasVib rioPrevotellaFusobacte rium . Group: Biochemicals. Alternative Names: Polymyxin E. sulfate; Belcomycine; Colomycin. Grades: Highly Purified. CAS No. 1264-72-8. Pack Sizes: 250mg, 1g, 5g, 10g. Molecular Formula: x(C??H???N??O??)? + x(C ??H??N??O??)B.xH?, Molecular Weight: 1169.46. US Biological Life Sciences. USBiological 1
Worldwide
Cyclogregatin It is produced by the strain of Aspergillus panamensis. It has anti-bacterial and fungal activity, but its antibacterial and fungal activity is lower than polymyxin A. It inhibits airy ascites carcinoma with MIC of 10 μg/mL (Gregatin A is 2 μg/mL). Synonyms: 4H-Furo(2,3-b)pyran-3,4(2H)-dione, 2-(1,3-hexadienyl)-5,6-dihydro-2,6-dimethyl-. CAS No. 120167-25-1. Molecular formula: C15H18O4. Mole weight: 262.30. BOC Sciences 5
lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase Integral membrane protein present in the inner membrane of certain Gram negative endobacteria. In strains that do not produce 3-deoxy-D-manno-octulosonic acid (Kdo), the enzyme adds a single arabinose unit to the 1-phosphate moiety of the tetra-acylated lipid A precursor, lipid IVA. In the presence of a Kdo disaccharide, the enzyme primarily adds an arabinose unit to the 4-phosphate of lipid A molecules. The Salmonella typhimurium enzyme can add arabinose units to both positions. Group: Enzymes. Synonyms: undecaprenyl phosphate-α-L-Ara4N transferase; 4-amino-4-deoxy-L-arabinose lipid A transferase; polymyxin resistance protein PmrK; arnT (gene name). Enzyme Commission Number: EC 2.4.2.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2672; lipid IVA 4-amino-4-deoxy-L-arabinosyltransferase; EC 2.4.2.43; undecaprenyl phosphate-α-L-Ara4N transferase; 4-amino-4-deoxy-L-arabinose lipid A transferase; polymyxin resistance protein PmrK; arnT (gene name). Cat No: EXWM-2672. Creative Enzymes
SPR206 acetate SPR206 acetate is a polymyxin analog with antibiotic activity against Gram-negative pathogens , including multidrug-resistant (MDR) variants. SPR206 acetate has an anti-bacterial infection effect by interacting with the bacteriums outer membrane. The MIC values of SPR206 acetate against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301 are both 0.125 mg/L [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2408422-41-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-128780B. MedChemExpress MCE
SPR741 SPR741 is a cationic peptide derived from polymyxin B and is a potentiator molecule. SPR741 inhibits multidrug-resistant Gram-negative bacteria. The spectrum of activity of the antibiotic can be widened when used in combination with SPR741 TFA. Synonyms: NAB741. Grades: >98%. CAS No. 1179330-52-9. Molecular formula: C44H73N13O13. Mole weight: 992.13. BOC Sciences 6
Tyrothricin Tyrothricin is a cyclic polypeptide-antibiotic mixture from Bacillus brevis. It is a locally effective antibiotic effective against gram-positive bacteria. It is sometimes combined with benzocaine 5mg to provide relief from sore throats. In systemic intake it can lead to severe side effects, therefore, the use is limited to topical application.Tyrothricin belongs to the pharmacologically related group of polypeptide antibiotic compounds including colistin, polymyxin B and bacitracin. There is no cross-resistance to these three agents. Group: Inhibitors. Alternative Names: bactratycin; coltirot; dermotricine; duboscrudecrystals; hydrotricine; intradermtyrothricin; martricin; soluthricin. CAS No. 1404-88-2. Molecular formula: C65H85N11O13. Mole weight: 179.17112. Appearance: Solid. Purity: ≥96.0%. Density: 1.32 g/cm³. Catalog: ACM1404882. Alfa Chemistry.
undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase The enzyme shows no activity with UDP-4-amino-4-deoxy-β-L-arabinose. Group: Enzymes. Synonyms: undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase; polymyxin resistance protein PmrF; UDP-4-amino-4-deoxy-α-L-arabinose:ditrans,polycis-undecaprenyl phosphate 4-amino-4-deoxy-α-L-arabinosyltransferase. Enzyme Commission Number: EC 2.4.2.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2683; undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; EC 2.4.2.53; undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase; polymyxin resistance protein PmrF; UDP-4-amino-4-deoxy-α-L-arabinose:ditrans,polycis-undecaprenyl phosphate 4-amino-4-deoxy-α-L-arabinosyltransferase. Cat No: EXWM-2683. Creative Enzymes

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