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| Product | Description | |
|---|---|---|
| Prazosin | Prazosin, a selective and orally active antagonist of adrenergic alpha-1, is a synthetic piperazine derivative to treat high blood pressure and anxiety, PTSD, and panic disorder. Uses: Adrenergic alpha-1 receptor antagonists. Synonyms: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone Douglas Brand of Prazosin Hydrochloride Furazosin HCL, Prazosin Hydrochloride, Prazosin Minipress Pfizer Brand of Prazosin Hydrochloride Pratsiol Prazosin Prazosin HCL Prazosin. Grades: 95%. CAS No. 19216-56-9. Molecular formula: C19H21N5O4. Mole weight: 383.40. |  |
| Prazosin | Prazosin is an α-adrenergic receptor antagonist. Prazosin can reduce inflammation, relieve anxiety, alleviate panic, prevent memory decline, and modulate the pain-relieving effects of opioids. Prazosin can be used in the study of hypertension and Alzheimers disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 19216-56-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B0193. |  |
| Prazosin-d8 | Heterocyclic Organic Compound. Alternative Names: 4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-d8]-2-furanylmethanone; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonxyl) piperazine-d8; Adversuten-d8; Adverszuten-d8; Alpress LP-d8. CAS No. 1006717-55-0. Molecular formula: C19H13D8N5O4. Mole weight: 391.45. Purity: 0.96. IUPACName: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,2,3,3,5,5,6,6-octadeuteriopiperazin-1-yl]-(furan-2-yl)methanone. Catalog: ACM1006717550. |  |
| Prazosin-d8 | Labeled Prazosin. An antihypertensive. α1-Adrenergic blocker. Group: Biochemicals. Alternative Names: 4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl-d8]-2-furanylmethanone; 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4- (2-furanylcarbonxyl) piperazine-d8; Adversuten-d8; Adverszuten-d8; Alpress LP-d8. Grades: Highly Purified. CAS No. 1006717-55-0. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Prazosin-d8 | Prazosin-d 8 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1006717-55-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193S. | |
| Prazosin-d8 hydrochloride | Prazosin-d8 hydrochloride is the deuterium labeled Prazosin hydrochloride. Prazosin hydrochloride is an alpha-adrenergic blocker [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189508-34-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193AS. | |
| Prazosin HCl (Furazosin HCl) | Prazosin HCl, a quinazoline derivative, is the first of a new chemical class of antihypertensives. Synonyms: cp-12299-1. Grades: >98%. CAS No. 19237-84-4. Molecular formula: C19H21N5O4·HCl. Mole weight: 419.86. | |
| Prazosin hydrochloride | Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders [1]. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC 50 of 0.15 nM [2].Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC 50 s of 1.8, and 13 μM, respectively [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19237-84-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0193A. | |
| Prazosin Hydrochloride | Prazosin Hydrochloride (Terazosin EP Impurity K) is an antihypertensive. α1-Adrenergic blocker. Prazosin hydrochloride, a quinazole derivative, is a very potent and highly selective antagonist for apha-1-adrenoceptors (affinity for alpha-1 is about 1000-fold greater than for alpha-2 receptors). Mainly used as a clinic vasodilator for blood pressure control without increasing the heart rate or significantly impairing sympathetic functions. Has also been used clinically to treat anxiety, PTSD, and panic disorder. An excellent candidate for research studying brain functions mediated through alpha-1-adrenergic receptors, such as reward, pleasure, aggression, fear, anxiety, and addiction. Group: Biochemicals. Alternative Names: [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone Hydrochloride; 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4- (2-furanylcarbonxyl) piperazine Hydrochloride; Adversuten; Adverszuten; Alpress LP; Furazosin; Lentopres; NSC 292810; Peripress; Terazosin EP Impurity K. Grades: Highly Purified. CAS No. 19237-84-4. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 419.86r. US Biological Life Sciences. | Worldwide |
| Prazosin N-β-D-Glucuronide | Prazosin N-β-D-Glucuronide is a metabolite of Prazosin, an inverse agonist at alpha-1 adrenergic receptor. Prazosin is a sympatholytic drug used to treat high blood pressure, anxiety, and posttraumatic stress disorder (PTSD). Synonyms: Prazosin N-glucuronide; (2S,3S,4S,5R,6R)-6-((2-(4-(furan-2-carbonyl)piperazin-1-yl)-6,7-dimethoxyquinazolin-4-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; Prazosin metabolite M13; N-{2-[4-(2-Furoyl)-1-piperazinyl]-6,7-dimethoxy-4-quinazolinyl}-β-D-glucopyranuronosylamine; β-D-Glucopyranuronosylamine, N-[2-[4-(2-furanylcarbonyl)-1-piperazinyl]-6,7-dimethoxy-4-quinazolinyl]-. Grades: ≥95%. CAS No. 944943-73-1. Molecular formula: C25H29N5O10. Mole weight: 559.54. | |
| 2,2'-(1,4-Piperazinediyl)bis[6,7-dimethoxy-4-quinazolinamine] (Terazosin Impurity) | An impurity of selective alpha 1 antagonists: Terazosin and Prazosin. Group: Biochemicals. Grades: Highly Purified. CAS No. 102839-00-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline | Metabolite of Prazosin. It is also an impurity arising in the synthesis of Terazosin. Group: Biochemicals. Alternative Names: 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine; 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline; 4-Amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline; 4-Amino-6, 7-dimethoxy-2- (1-piperazinyl) quinazoline. Grades: Highly Purified. CAS No. 60547-97-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline-d8 | Labeled metabolite of Prazosin. Group: Biochemicals. Alternative Names: 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine-d8; 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline-d8; 4-Amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline-d8; 4-Amino-6, 7-dimethoxy-2- (1-piperazinyl) quinazoline-d8. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3-MPPI | 3-MPPI is a very potent ligand for α1 sites (Ki for displacement of prazosin = 0.2 nM) and regulates smooth muscle contraction. 3-MPPI shows different binding properties for each α1 subtype (pKi values are 8.74, 9.44 and 9.57 for α1B, α1D and α1A adrenoceptors respectively). Synonyms: 3-MPPI; 3 MPPI; 3MPPI; 2-[(4-Phenylpiperazin-1-yl)methyl]-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one. CAS No. 133399-65-2. Molecular formula: C23H25N5O3. Mole weight: 419.48. | |
| 4-N-Boc-2-methylpiperazine. | 4-N-Boc-2-methylpiperazine is a boc protetcted piperazine derivative used in the preparation of prazosin-related compounds with blocking activity toward α-adrenoreceptors. Group: Biochemicals. Alternative Names: 3-Methyl-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; (±)-1,1-Dimethylethyl 3-Methylpiperazine-1-carboxylate; 1-tert-Butoxycarbonyl-3-methylpiperazine; 3-Methylpiperazine-1-carboxylic Acid tert-Butyl Ester; tert-Butyl 3-methyl-1-piperazinecarboxylate; 4-tert-Butoxycarbonyl-2-methylpiperazine. Grades: Highly Purified. CAS No. 120737-59-9. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 6,7-Dimethoxy-2,4-quinazolinediamine | A metabolite of Terazosin and a minor metabolite of Prazosin. Displays high affinity for the α1-Adrenoceptors, important in the treatment of hypertension. Group: Biochemicals. Alternative Names: 2,4-Diamino-6,7-dimethoxyquinazoline. Grades: Highly Purified. CAS No. 60547-96-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Bicyclo[2.2.2]octa-2,5-diene-2-carboxylic Acid | Intermediate in the production of Prazosin and Prazosin analogs. Group: Biochemicals. Grades: Highly Purified. CAS No. 102589-30-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| CP 100356 | CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grades: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64. | |
| CP-100356 Hydrochloride | CP-100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. CP-100356 also inhibits prazosin transport in human breast cancer resistance protein (BCRP)-transfected MDCKII cells, suggesting that it acts as a dual inhibitor. CP-100356 does not inhibit multidrug resistance-associated protein 2 (MPR2 IC50 >15 mM). Group: Biochemicals. Alternative Names: 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine Monohydrochloride. Grades: Highly Purified. CAS No. 142715-48-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CP 59430 | CP 59430 is an azide analog of prazosin. It is a selective alpha 1-adrenergic receptor antagonist. Synonyms: CP 59430; CP59430; CP-59430. 2-(4-(4-Azidobenzoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline. Grades: 98%. CAS No. 86329-06-8. Molecular formula: C21H22N8O3. Mole weight: 434.45. | |
| Doxazosin-d8 | Labeled Doxazosin, a selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Doxazosin, Mesylate (UK-33274-27, Alfadil, Cardenalin) | A selective a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Alternative Names: UK-33274-27, Alfadil, Cardenalin. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| Methoxamine hydrochloride | Methoxamine hydrochloride is a selective alpha1-adrenergic receptor agonist. Methoxamine hydrochloride causes vasoconstriction and increased peripheral vascular resistance [1] [2]. Methoxamine hydrochloride significantly increased the overflow of ATP, ADP and AMP, but not adenosine, by a prazosin-sensitive mechanism in the rabbit pulmonary artery [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1298. | |
| Prazobind | Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC 50 =1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SZL 49. CAS No. 107021-36-3. Pack Sizes: 1 mg. Product ID: HY-118335. | |
| Prazobind-d8 | α1-Adrenoceptor alkylating reagent. A labeled Prazosin analog. Group: Biochemicals. Alternative Names: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-bicyclo[2.2.2]octa-2,5-dienyl-carbonyl)-(piperazine-d8); SZL-49-d8. Grades: Highly Purified. CAS No. 1189701-23-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Terazosin EP Impurity E | One impurity of Terazosin, which is a piperazine derivative and has been found to be an α-1-adrenergic blocker. Uses: An impurity of selective alpha 1 antagonists: terazosin (t105000) and prazosin (p702325). Synonyms: 1,4-Bis(4-amino-6,7-dimethoxy-2-quinazolinyl)piperazine; 2,2'-(Piperazine-1,4-diyl)bis(6,7-dimethoxyquinazolin-4-amine). CAS No. 102839-00-9. Molecular formula: C24H28N8O4. Mole weight: 492.53. | |
| Terazosin, Hydrochloride | An a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Alternative Names: 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4-[ (tetrahydro-2-furanyl) carbonxyl]piperazine, Hydrochloride. Grades: Highly Purified. CAS No. 63074-08-8. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Upidosin | Upidosin (Rec 15/2739) is an α-1 adrenoceptor ( α-1 AR ) antagonist. Upidosin shows moderate selectivity for the α-1A AR subtype. Upidosin shows uroselectivity in urethra and prostate with a K b value of 2-3 nM higher than in ear artery and aorta with a K b value of 20-100 nM. Upidosin inhibits [3H]prazosin binding to cloned human α-1A adrenergic receptor. Upidosin can be used for the research of urethral obstruction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rec 15/2739; Recordati 15/2739; SB 216469. CAS No. 152735-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106954. | |
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