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| Product | Description | |
|---|---|---|
| Proguanil | Proguanil, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil is a dihydrofolate reductase ( DHFR ) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0806. |  |
| Proguanil hydrochloride | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics, Testing Standards. Formula: C11H15Cl2N5. CAS No. 537-21-3. Prepack ID 10785411-25mg. Molecular Weight 288.18. See USA prepack pricing. |  |
| Proguanil hydrochloride | Proguanil hydrochloride, an antimalarial proagent, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase ( DHFR ) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 637-32-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0806A. | |
| Proguanil hydrochloride | Proguanil hydrochloride, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. Uses: Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. Group: Solvents. Alternative Names: Chlorguanide, N1- (4-Chlorophenyl) -N5-isopropylbiguanide, Proguanil hydrochloride. CAS No. 637-32-1. Molecular formula: C11H17Cl2N5. Mole weight: 290.19. IUPACName: hydrogen 1- ({amino[ (4-chlorophenyl) amino]methylidene}amino) -N'- (propan-2-yl) methanimidamide chloride. Canonical SMILES: [H+]. [Cl-]. CC(C)N=C(N)N=C(N)NC1=CC=C(Cl)C=C1. ECNumber: 211-283-7. Catalog: ACM637321. |  |
| Proguanil hydrochloride | Proguanil hydrochloride is the hydrochloride salt form of proguanil, which is a synthetic biguanide derivative of pyrimidine. It is used as an folate antagonist with antimalarial property. It is used to treat and prevent malaria together with chloroquine or atovaquone. lt is converted by the liver to its active metabolite, cycloguanil. It may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. It was developed by AstraZeneca and has been listed. Uses: Proguanil hydrochloride is used as an folate antagonist with antimalarial property. Synonyms: 1-(p-chlorophenyl)-5-isopropylbiguanidehydrochloride; 1-(p-chlorophenyl)-5-isopropyl-biguanidmonohydrochloride; 3359rp; chlorguanidehydrochloride; chloroguanidehydrochloride; chloroguanidinehydrochloride; diguanyl; drinupalhydrochloride. Grades: BP/EP/USP. CAS No. 637-32-1. Molecular formula: C11H17Cl2N5. Mole weight: 290.19. |  |
| Chlorguanide Impurity A (Proguanil Impurity A) | An intermediate commonly used for the synthesis of guanide derivatives. An Impurity in the synthesis of Chlorguanide. Synonyms: N-Cyano-N'-(1-methylethyl)guanidine; Isopropyldicyandiamide; 3-Cyano-1-isopropylguanidine; NSC 643485. Grades: > 95%. CAS No. 44830-55-9. Molecular formula: C5H10N4. Mole weight: 126.16. | |
| Chlorguanide-d4 Hydrochloride | Antimalarial. Group: Biochemicals. Alternative Names: N-(4-Chlorophenyl-d4)-N'-(1-methylethyl)-imidodicarbonimidic Diamide Hydrochloride; 1-(p-Chlorophenyl-d4)-5-isopropylbiguanide Hydrochloride; Bigumal-d4; Chlorguanid-d4; Chloroguanide-d4; Paludrin-d4; Proguanil-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Chlorguanide Hydrochloride | Antimalarial. Group: Biochemicals. Alternative Names: N-(4-Chlorophenyl)-N'-(1-methylethyl)-imidodicarbonimidic Diamide Hydrochloride;1-(p-Chlorophenyl)-5-isopropylbiguanide Hydrochloride; Bigumal; Chlorguanid; Chloroguanide; Paludrin; Proguanil; M-4888. Grades: Highly Purified. CAS No. 637-32-1. Pack Sizes: 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Cycloguanil-d4 hydrochloride | Cycloguanil-d4 (hydrochloride) is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes. Group: Isotope-labeled environmental contaminants. CAS No. 1189427-23-3. Molecular formula: C11H11D4Cl2N5. Mole weight: 292.2. Canonical SMILES: CC1 (N (C2=C ([2H])C ([2H])=C (C ([2H])=C2[2H])Cl)C (N)=NC (N)=N1)C. Cl. Catalog: ACM1189427233. | |
| Cycloguanil hydrochloride | Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12784A. | |
| Cycloguanil hydrochloride | Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes. Group: Inhibitors. Alternative Names: 1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine Hydrochloride; BN 2410; Chloroguanide Triazine Hydrochloride; Cycloguanil Hydrochloride; NSC 3074. CAS No. 152-53-4. Molecular formula: C11H15Cl2N5. Mole weight: 288.18. Appearance: White Solid. Purity: 0.96. IUPACName: 1-(4-chlorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine hydrochloride. Canonical SMILES: CC1(N=C(N=C(N1C2=CC=C(C=C2)Cl)N)N)C. Cl. Catalog: ACM152534. | |
| Cycloguanil hydrochloride | Cycloguanil is an active metabolite of proguanil, produced by the cytochrome P450 2C19 isoform. It is also an inhibitor of dihydrofolate reductase (DHFR) (Kis = 0.3 and 1.5 nM for Plasmodium and human forms, respectively). Uses: Antimalarials. Synonyms: Chloroguanide Triazine; NSC 3074; 1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine monohydrochloride. Grades: ≥95%. CAS No. 152-53-4. Molecular formula: C11H14ClN5·HCl. Mole weight: 288.2. | |
| N1-(4-Chlorophenyl)-N5-isopropylbiguanide | A prophylactic antimalarial drug effective against sporozoites. Synonyms: proguanil; Chloroguanide; Paludrin; Bigumal; Proguanilum; 1-(p-Chlorophenyl)-5-isopropylbiguanide. Grades: > 95 %. CAS No. 500-92-5. Molecular formula: C11H16ClN5. Mole weight: 253.73. | |
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