Prostacyclin Suppliers USA
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Product | Description | |
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Prostacyclin sodium salt Quick inquiry Where to buy Suppliers range | Prostacyclin sodium salt. Group: Biochemicals. Alternative Names: (5Z,9a,11a,13E,15S)-6,9-epoxy-11,15-dihydroxy-prosta-5,13-dien-1-oic acid sodium salt; Epoprostenol sodium; Flolan. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. Molecular Formula: C20H32NaO5. US Biological Life Sciences. | Worldwide |
15-epi-Prostacyclin Sodium Salt Quick inquiry Where to buy Suppliers range | 15-epi-Prostacyclin Sodium Salt is a derivative of Prostacyclin Sodium Salt (P839060) which is an eicosanoid that prevents the formation of platelet plugs and is an effective vasodilator. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C20H31NaO5, Molecular Weight: 374.45. US Biological Life Sciences. | Worldwide |
Prostaglandin I2, Sodium Salt (PGI2, Prostacyclin) Quick inquiry Where to buy Suppliers range | Potent vasodilatory prostaglandin produced by the endothelium. Induces vasodilation, stimulates cAMP formation. Exhibits cytoprotective and fibrinolytic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 61849-14-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
16(R)-Iloprost Quick inquiry Where to buy Suppliers range | Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Synonyms: Iloprost R-isomer; (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 74843-13-3. Molecular formula: C22H32O4. Mole weight: 360.5. | |
16(S)-Iloprost Quick inquiry Where to buy Suppliers range | Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Synonyms: Iloprost S-isomer; (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 74843-14-4. Molecular formula: C22H32O4. Mole weight: 360.5. | |
(1E) -1- [ (3'aS, 4'R, 5'R, 6'aR) -5'- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] hexahydro-5, 5-dimethylspiro [1, 3-dioxane-2, 2' (1'H) -pentalen] -4'-yl] -4-methyl-1-octen-6-yn-3-one Quick inquiry Where to buy Suppliers range | (1E) -1- [ (3'aS, 4'R, 5'R, 6'aR) -5'- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] hexahydro-5, 5-dimethylspiro [1, 3-dioxane-2, 2' (1'H) -pentalen] -4'-yl] -4-methyl-1-octen-6-yn-3-one is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud's phenomenon and ischemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 116896-29-8. Pack Sizes: 250ug, 1mg. Molecular Formula: C28H46O4Si, Molecular Weight: 474.75. US Biological Life Sciences. | Worldwide |
(1E, 3R, 4S) -1- [ (3'aS, 4'R, 5'R, 6'aR) -5'- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] hexahydro-5, 5-dimethylspiro [1, 3-dioxane-2, 2' (1'H) -pentalen] -4'-yl] -4-methyl-1-octen-6-yn-3-ol Quick inquiry Where to buy Suppliers range | (1E, 3R, 4S) -1- [ (3'aS, 4'R, 5'R, 6'aR) -5'- [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] hexahydro-5, 5-dimethylspiro [1, 3-dioxane-2, 2' (1'H) -pentalen] -4'-yl] -4-methyl-1-octen-6-yn-3-ol is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud's phenomenon and ischemia. Group: Biochemicals. Grades: Highly Purified. CAS No. 910916-95-9. Pack Sizes: 250ug, 1mg. Molecular Formula: C28H48O4Si. US Biological Life Sciences. | Worldwide |
2,9-Dihydroxy Treprostinil Quick inquiry Where to buy Suppliers range | Descarboxy Treprostinil is an impurity in the synthesis of Treprostinil (T719500), Synthetic analog of Prostacyclin (P839060). Antihypertensive. Treprostinil, marketed under the trade name Remodulin is a medication used to treat pulmonary arterial hypertension (PAH). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C23H34O6, Molecular Weight: 406.51. US Biological Life Sciences. | Worldwide |
2-Chloro-5,6-diphenylpyrazine Quick inquiry Where to buy Suppliers range | 2-Chloro-5,6-diphenylpyrazine is a diphenylpyrazine derivative used in a study to determine a novel class of prostacyclin receptor agonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 41270-66-0. Pack Sizes: 250mg, 1g. Molecular Formula: C16H11ClN2, Molecular Weight: 266.72. US Biological Life Sciences. | Worldwide |
(α R) -α -Methyl-N- [ (1R) -1-phenylethyl] benzenemethanamine Hydrochloride Quick inquiry Where to buy Suppliers range | (α R) -α -Methyl-N- [ (1R) -1-phenylethyl] benzenemethanamine Hydrochloride is used in the synthesis of the highly potent anti-metastatic prostacyclin analogue Cicaprost (C432750). Also used in the synthesis of a key A-Ring intermediate in the preparation of 1α-fluoro vitamin D3 analogues. Group: Biochemicals. Alternative Names: Bis((1R)-1-phenylethyl)amine Hydrochloride; [R-(R*,R*)]-α-Methyl-N-(1-phenylethyl)-Benzenemethanamine Hydrochloride. Grades: Highly Purified. CAS No. 82398-30-9. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
Beraprost Quick inquiry Where to buy Suppliers range | Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. Beraprost acts by binding to prostacyclin membrane receptors ultimately inhibiting the release of Ca2+ from intracellular storage sites. Beraprost sodium (beraprost) is a stable, orally active prostacyclin analogue with vasodilatory, antiplatelet and cytoprotective effects. Synonyms: Procylin; Careload; Dorner; Beraprost sodium; TRK-100; TRK 100; TRK100; YM-533; YM533; YM 533; ML-1129; ML 1129; ML1129; MDL 201229; MDL-201229; MDL201229. CAS No. 88430-50-6. Molecular formula: C24H30O5. Mole weight: 398.49. | |
Beraprost sodium salt Quick inquiry Where to buy Suppliers range | Beraprost is an analog of prostacyclin in which the unstable enol-ether has been replaced by a benzofuran ether function. It inhibits platelet aggregation in healthy subjects and in diabetic patients at similar doses. Synonyms: Beraprost sodium; 4-[2-hydroxy-1-[(E)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoate sodium salt. Grades: >95%. CAS No. 88475-69-8. Molecular formula: C24H29NaO5. Mole weight: 420.49. | |
Beraprost Sodium Salt Quick inquiry Where to buy Suppliers range | Platelet aggregation inhibitor; stable analog of Prostacyclin. Antithrombotic; vasodilator (peripheral). Group: Biochemicals. Alternative Names: dl-4- [ (1R, 2R, 3aS, 8bS) -2, 3, 3a, 8b-Tetrahydro-2-hydroxy- [ (3S, 4RS) -3-hydroxy-4-methyl-oct-6-yne- (E) -1-enyl] -5-cyclopenta [b] benzofuranyl] butanoic Acid Sodium; MDL 201229; ML 1229; Dorner; Procylin. Grades: Highly Purified. CAS No. 88475-69-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Bmy 42393 Quick inquiry Where to buy Suppliers range | BMY-42393 is a selective platelet aggregation inhibitor. It is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation with IC50 value range from 0.3 to 2.0 mM. BMY-42393 can stimulate platelet adenylate cyclase with EC50 value of 25 nM. BMY 42393 can also inhibit thrombin-induced elevation of intracellular free calcium. Research for the treatment of Hyperlipidaemia was discontinued. Uses: Hyperlipidaemia. Synonyms: BMY-42393; BMY 42393; BMY42393. SCHEMBL675089; AC1L304B; CHEMBL117835;2-[3-[2-(4,5-diphenyl-1,3-oxazol-2-yl)ethyl]phenoxy]acetic acid. Grades: 98%. CAS No. 136451-58-6. Molecular formula: C25H21NO4. Mole weight: 399.45. | |
BMY 45778 Quick inquiry Where to buy Suppliers range | BMY 45778 is a non-prostanoid prostacyclin mimetic that acts as a partial agonist of IP1 prostacyclin receptors. It inhibits platelet aggregation in vitro (IC50 = 27-35 nM). Synonyms: BMY 45778; BMY45778; BMY-45778. [3-(4,5-Diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]acetic acid. Grades: ≥99% by HPLC. CAS No. 152575-66-1. Molecular formula: C26H18N2O5. Mole weight: 438.44. | |
Carbaprostacyclin methyl ester Quick inquiry Where to buy Suppliers range | Carbaprostacyclin is a stable analog of prostacyclin (prostaglandin I2) which can activate the prostacyclin receptor or PPARδ, which ameliorates excess lipid accumulation in diabetic rat placentas. Carbaprostacyclin methyl ester is a more lipid soluble form of carbaprostacyclin. As a result, it may more readily enter cells to activate PPAR&delta. The biological activities of carbaprostacyclin methyl ester have not been studied. Synonyms: Carbaprostacyclin methyl ester; 69552-55-2; methyl (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoate; SCHEMBL16800383; CHEBI:197272; Methyl 5-((3aS,4R,5R,6aS,E)-5-hydroxy-4-((S,E)-3-hydroxyoct-1-en-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoate. Grades: ≥98%. CAS No. 69552-55-2. Molecular formula: C22H36O4. Mole weight: 364.5. | |
CAY10449 Quick inquiry Where to buy Suppliers range | CAY10449 is one of compounds which are found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase. It also inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 3 nM. Synonyms: CAY 10449; CAY-10449. Grades: ≥98%. Molecular formula: C19H21N3O2. Mole weight: 323.4. | |
Epoprostenol Sodium Quick inquiry Where to buy Suppliers range | Epoprostenol Sodium is the sodium salt form of epoprostenol, which is a synthetic prostacyclin. It has vasodilatory and anticoagulant activity. It is a short-lived product of the cyclooxygenase pathway in vascular endothelial cells. It prevents the formation of platelet plugs and is an effective vasodilator. It is a potent inhibitor of platelet aggregation by antagonizing thromboxane A2 and stimulating platelet adenylyl cyclase. It directly simulates prostaglandin receptors in arterial vascular smooth muscle, thereby causing vasodilatation. lt is also used for the treatment of pulmonary hypertension. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. It is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract. It was developed by GlaxoSmithKline and has been listed. Uses: Epoprostenol sodium has vasodilatory and anticoagulant activity. it prevents the formation of platelet plugs and is an effective vasodilator. lt is also used for the treatment of pulmonary hypertension. Synonyms: Prostacyclin Sodium Salt; (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-Dihydroxy-prosta-5,13-dien-1-oic Acid Sodium Salt; Flolan. Grades: >99 %. CAS No. 61849-14-7. Molecular formula: C20H31O5Na. Mole weight: 374.45. | |
FR-181157 Free base Quick inquiry Where to buy Suppliers range | FR-181157 is an orally active prostacyclin mimetic that shows high potency and agonist efficacy at the IP receptor. Synonyms: sodium;2-[3-[[(1S)-2-(4,5-diphenyl-1,3-oxazol-2-yl)cyclohex-2-en-1-yl]methyl]phenoxy]acetate; FR 181157; FR181157; 200433-03-0 (FR-181157 Free Base). Grades: >98%. CAS No. 200433-03-0. Molecular formula: C30H26NNaO4. Mole weight: 487.52. | |
FR-193262 Quick inquiry Where to buy Suppliers range | FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability. Synonyms: FR-193262; FR 193262; FR193262; sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base). Grades: >98%. CAS No. 187992-22-9. Molecular formula: C31H29N2NaO4. Mole weight: 516.56. | |
GW 848687X Quick inquiry Where to buy Suppliers range | GW 848687X is a potent and selective antagonist of EP1 receptor (IC50 = 2.5 nM). GW 848687X displays >400-fold selectivity for EP1 relative to the other EP receptor subtypes, the PGD2 receptor, DP1, and the prostacyclin receptor, IP. Synonyms: 6-[2-[5-chloro-2-[(2,4-digluorophenyl)methoxy]phenyl]-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 612831-24-0. Molecular formula: C24H18ClF2NO3. Mole weight: 441.9. | |
MRE-269 Quick inquiry Where to buy Suppliers range | MRE-269 is an orally available and long-acting prostacyclin receptor agonist prodrug used for the treatment of pulmonary arterial hypertension. Uses: Prostacyclin receptor agonist. Synonyms: MRE-269; MRE269; MRE 269; ACT-333679; ACT 333679; ACT333679. [4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]butoxy]-acetic acid; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-acetic Acid. Grades: ≥98%. CAS No. 475085-57-5. Molecular formula: C25H29N3O3. Mole weight: 419.5. | |
Nafazatrom Quick inquiry Where to buy Suppliers range | Nafazatrom is a pyrazolinone derivative. It increases endogenous prostacyclin (PGI2) and has potential antimetastatic activities. It is used an antithrombotic drug that increases PGI2 levels. It inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, which prolongs the biological half-life of PGI2 and prevents intravascular coagulation. It also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. It is a lipoxygenase inhibitor, reduces stimulated Prolactin secretion. It also reduces the incidence of accompanying arrhythmias in myocardial injuries. Uses: Nafazatrom is used an antithrombotic drug. Synonyms: 2,4-Dihydro-5-methyl-2-[2-(2-naphthalenyloxy)ethyl]-3H-pyrazol-3-one; Bay-g-6575; BAY g 6575; 3-methyl-1-(2-(naphthalen-2-yloxy)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 59040-30-1. Molecular formula: C16H16N2O2. Mole weight: 268.32. | |
N,N-Diethylaminoethyl 2,2-diphenylvalerate hydrochloride (SKF-525A HCl) Quick inquiry Where to buy Suppliers range | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: α-Phenyl-α-Propylbenzeneacetic Acid 2-(Diethylamino)ethyl Ester Hydrochloride; 2,2-Diphenylvaleric Acid 2-(Diethylamino)ethyl Ester Hydrochloride; 2-(Diethylamino)ethyl 2,2-Diphenylvalerate Hydrochloride; Proadifen Hydrochloride; RP 5171; SKF 525; U 5446. Grades: Highly Purified. CAS No. 62-68-0. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClNO?, Molecular Weight: 389.96. US Biological Life Sciences. | Worldwide |
Novokinin Quick inquiry Where to buy Suppliers range | Novokinin, designed based on the structure of ovokinin, is an angiotensin AT2 receptor agonist (Ki = 7.35 μM) that displays 93-fold selectivity over AT1. Novokinin exhibits vasorelaxing and hypotensive activity via activation of the IP (prostacyclin) receptor, and suppresses food intake via activation of PGE2-EP4 interaction. Synonyms: Novokinin; L-arginyl-L-prolyl-L-leucyl-L-lysyl-L-prolyl-L-tryptophan. CAS No. 358738-77-9. Molecular formula: C39H61N11O7. Mole weight: 795.98. | |
Novokinin acetate Quick inquiry Where to buy Suppliers range | Novokinin acetate is an angiotensin AT2 receptor agonist (Ki = 7.35 μM) that displays 93-fold selectivity over AT1. Novokinin exhibits vasorelaxing and hypotensive activity via activation of the IP (prostacyclin) receptor, and suppresses food intake via activation of PGE2-EP4 interaction. Synonyms: H-Arg-Pro-Leu-Lys-Pro-Trp-OH.CH3CO2H; L-arginyl-L-prolyl-L-leucyl-L-lysyl-L-prolyl-L-tryptophan acetic acid; Acetic acid, compd. with (L-arginyl-yl-L-leucyl-yl-L-lysyl-yl-L-prolyl-yl-L-prolyl-yl)-L-Tryptophan (1:1). Grades: ≥95%. CAS No. 2803405-27-6. Molecular formula: C41H65N11O9. Mole weight: 856.02. | |
NS-304 Quick inquiry Where to buy Suppliers range | NS-304 is a selective prostacyclin IP1 receptor agonist as prodrug of the active form of MRE-269 with a Ki value of 20 nM. Uses: Antihypertensive agents. Synonyms: Selexipag; NS304; NS 304; ACT-293987; ACT293987; ACT 293987; 2-[4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)acetamide. Grades: ≥95%. CAS No. 475086-01-2. Molecular formula: C26H32N4O4S. Mole weight: 496.6. | |
ONO-1301 Quick inquiry Where to buy Suppliers range | ONO-1301, a naphthalen derivative, has been found to be a prostacyclin agonist and could be studied as an anti-inflammatory agent works partially through leading the formation of hepatocyte growth factor. Synonyms: Ono1301; Ono-1301; Ono 1301; 7,8-Dihydro-5-[(E)-[[-(3-pyridyl)benzylidene]aminooxy]ethyl]-1-naphthyloxy]acetic acid. Grades: 98%. CAS No. 176391-41-6. Molecular formula: C27H26N2O4. Mole weight: 428.48. | |
Proadifen Hydrochloride Quick inquiry Where to buy Suppliers range | Proadifen hydrochloride is a Cytochrome P450 inhibitor (IC50 = 19μM) and stimulate endothelial cell prostacyclin production. Uses: Cytochrome p-459 inhibitor; blocks glibenclamide-sensitive k+ channels. Synonyms: 2-(diethylamino)ethyl 2,2-diphenylpentanoate;hydrochloride;SKF-525A, Hydrochloride; Proadifen hydrochloride; NSC 170997; NSC-170997; NSC170997. Grades: ≥98%. CAS No. 62-68-0. Molecular formula: C23H32ClNO2. Mole weight: 389.96. | |
Ralinepag Quick inquiry Where to buy Suppliers range | This active molecular is a Epoprostenol receptor agonist which is an investigational drug candidate developed by Arena and intended for the treatment of vasospastic diseases, for an example, Pulmonary Arterial Hypertension. Ralinepag has the potential to mimic prostacyclin which elicits a potent vasodilation and inhibits platelet aggregation when binding to this receptor. In Jan 2015, Phase-II clinical trials in Pulmonary arterial hypertension in USA was on going. In Jul 2015, Phase-II clinical trials in Pulmonary arterial hypertension in Spain was on going. In Jul 2015, Arena initiated enrolment in a phase II extension trial for Pulmonary arterial hypertension in USA, Czech Republic, Hungary, Poland. Uses: Pulmonary arterial hypertension. Synonyms: 2- [ [4- [ [ (4-chlorophenyl) -phenylcarbamoyl] oxymethyl] cyclohexyl] methoxy] acetic acid,APD-811; APD 811; APD811; Ralinepag. Grades: 98%. CAS No. 1187856-49-0. Molecular formula: C23H26ClNO5. Mole weight: 431.91. | |
RO1138452 Quick inquiry Where to buy Suppliers range | RO1138452 is one of the most potent high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It exhibits no affinity at other prostanoid receptors (EP1-4, FP and TP) in a radioligand binding assay. RO1138452 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Synonyms: RO-1138452; RO1138452; RO 1138452; CAY10441; CAY-10441; CAY 10441; N-(4-(4-Isopropoxybenzyl)phenyl)-4,5-dihydro-1H-imidazol-2-amine. CAS No. 221529-58-4. Molecular formula: C19H23N3O. Mole weight: 309.413. | |
Ro 1138452 hydrochloride Quick inquiry Where to buy Suppliers range | Ro 1138452 is one of the most potent high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. It exhibits no affinity at other prostanoid receptors (EP1-4, FP and TP) in a radioligand binding assay. RO1138452 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Synonyms: Ro 1138452 hydrochloride; Ro1138452 hydrochloride; Ro-1138452 hydrochloride; 4,5-Dihydro-N-[4-[[4-(1-methylethoxy)phenyl]methyl]phenyl]-1H-imidazol-2-amine hydrochloride; Ro 1138452 Hcl. Grades: ≥98% by HPLC. Molecular formula: C19H23N3O.HCl. Mole weight: 345.87. | |
Rosmarinic Acid Quick inquiry Where to buy Suppliers range | Rosmarinic Acid is a phenolic compound with antioxidant and anti-inflammatory activity. Rosmarinic Acid has been shown to inhibit againts peroxidative damage to biomembranes. Rosmarinic Acid also suppresses endotoxin-induced activation of complement and concomitant prostacyclin biosynthesis. Group: Biochemicals. Alternative Names: ( α R) - α - [ [ (2E) -3- (3, 4-Dihydroxyphenyl) -1-oxo-2-propen-1-yl] oxy] -3, 4-dihydroxy Benzene propanoic Acid; 3,4-Dihydroxycinnamic Acid 2-Ester with 3-(3,4-dihydroxyphenyl)lactic Acid; Labiatenic Acid; Labiatic Acid; Mamorekku RUH 2; Meiji Red Perilla Polyphenol; RM 21A; Rosemaric Acid; Rosemary Acid; trans-Rosmarinic Acid; [R- (E) ] - α - [ [3- (3, 4-dihydroxyphenyl) -1-oxo-2-propenyl] oxy] -3, 4-dihydroxy Benzene propanoic Acid. Grades: Highly Purified. CAS No. 20283-92-5. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
SKF-525A, Hydrochloride (Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl) Quick inquiry Where to buy Suppliers range | Cytochrome P-459 inhibitor; blocks glibenclamide-sensitive K+ channels; inhibits neuronal nitric oxide synthetase; stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. Group: Biochemicals. Alternative Names: Proadifen, HCl, a-Phenyl-a-propylbenzeneacetic Acid 2-[Diethylamino]ethyl Ester, HCl. Grades: Highly Purified. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
Taprostene Quick inquiry Where to buy Suppliers range | Taprostene is a prostacyclin (PGI2) analog that acts as an agonist of the prostacyclin receptor, IP. Uses: Cardiovascular agents. Synonyms: CG 4203; Rheocyclan; 3-[(Z)-[(3aR,4R,5R,6aS)-4-[(E,3S)-3-cyclohexyl-3-hydroxyprop-1-enyl]-5-hydroxy-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]methyl]benzoic acid. Grades: ≥95%. CAS No. 108945-35-3. Molecular formula: C24H30O5. Mole weight: 398.5. | |
trans 2-Phenylcyclopropylamine Hydrochloride (Tranylcypromine, trans 2-Amino-1-phenyl-cyclopropane Hydrochloride) Quick inquiry Where to buy Suppliers range | A non-selective inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Tranylcypromine; trans 2-Amino-1-phenyl-cyclopropane Hydrochloride. Grades: Highly Purified. CAS No. 1986-47-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
Tranylcypromine Hemisulfate (Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA) Quick inquiry Where to buy Suppliers range | An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC50 <2uM for BHC110/LSD1). When combined with GSK-3 Inhibitor CHIR99021, causes reprogramming of human primary keratinocyte transduced with two factors, Oct4 and Klf4. Group: Biochemicals. Alternative Names: Trans (±) -2-Phenyl cyclopropanamine, Hemisulfate; SKF trans-355; 2-PCPA. Grades: Highly Purified. CAS No. 13492-01-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Treprostinil Quick inquiry Where to buy Suppliers range | Treprostinil is a vasodilator can be used for the treatment of pulmonary arterial hypertension. It is a synthetic analog of prostacyclin. Treprostinil is an epoprostenol receptor agonist and platelet aggregation inhibitor. Uses: The treatment of pulmonary arterial hypertension. Synonyms: Uniprost; Remodulin; Treprostinilo; Treprostinilum; 2-[[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[g]naphthalen-5-yl]oxy]acetic acid. Grades: ≥98%. CAS No. 81846-19-7. Molecular formula: C23H34O5. Mole weight: 390.51. | |
Treprostinil Acyl-β-D-Glucuronide Quick inquiry Where to buy Suppliers range | Treprostinil Acyl-β-D-Glucuronide is a metabolite of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI4) that is used for the treatment of pulmonary arterial hypertension (PAH). Synonyms: 1-[[[2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-(3-hydroxyoctyl)-1H-benz[f]inden-5-yl]oxy]acetate], [1R-[1α(S*), 2β, 3aα, 9aα]]-β-D-glucopyranuronic Acid; 1H-Benz[f]indene β-D-Glucopyranuronic Acid Derivative; Treprostinil-β-D-Glucuronide. CAS No. 148916-53-4. Molecular formula: C29H42O11. Mole weight: 566.64. | |
Treprostinil Dimer 1 Quick inquiry Where to buy Suppliers range | Treprostinil Dimer 1 is a metabolite of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI3) that is used for the treatment of pulmonary arterial hypertension (PAH). Synonyms: Treprostinil-2-yl Treprostinilate Ester; Benzyl 2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-(2-(((2R,3R,3aS,9aS)-2-hydroxy-3-((R)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-6-yl)oxy)acetoxy)octyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetate. Molecular formula: C46H66O9. Mole weight: 763.01. | |
Treprostinil Dimer 2 Quick inquiry Where to buy Suppliers range | Treprostinil Dimer 2 is a metabolite of Treprostinil. Treprostinil is an analogue of prostacyclin (PGI2) that is used for the treatment of pulmonary arterial hypertension (PAH). Synonyms: Treprostinil-3'-yl Treprostinilate Ester; Benzyl 2-(((1R,2R,3aS,9aS)-2-Hydroxy-1-((S)-3-(2-(((2R,3R,3aS,9aS)-2-hydroxy-3-((R)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-6-yl)oxy)acetoxy)octyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)acetate. Molecular formula: C46H66O9. Mole weight: 763.01. | |
U-51605 Quick inquiry Where to buy Suppliers range | U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). U-51605 is an inhibitor of both prostacyclin (PGI) and thromboxane (TX) synthases, as well as a partial agonist at TP receptors. Synonyms: U 51605; U51605; 7-(6-Oct-1-enyl-2,3-diazabicyclo[2.2.1]hept-2-en-5-yl)hept-5-enoic acid. Grades: ≥98%. CAS No. 64192-56-9. Molecular formula: C20H32N2O2. Mole weight: 332.5. |