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| Product | Description | |
|---|---|---|
| Prostaglandin E2 | Prostaglandin E2 is a naturally occurring COX product used as a medication in labor induction, bleeding after delivery, and termination of pregnancy. It directly targets muscle stem cells (MuSCs) via EP4 receptor, resulting in MuSC expansion. Uses: Endogenous prostaglandin and primary product of arachidonic acid/cyclooxygenase pathway. Synonyms: Dinoprostone; PGE2; Prostin E2; Prepidil. Grades: >98%. CAS No. 363-24-6. Molecular formula: C20H32O5. Mole weight: 352.47. |  |
| Prostaglandin E2 | Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation. Uses: Scientific research. Group: Natural products. Alternative Names: PGE2; Dinoprostone. CAS No. 363-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101952. |  |
| Prostaglandin E2 (Dinoprostone) | The most common and most biologically potent of mammalian prostaglandins. Isolated from sheep prostate. Oxytocic; abortifacient. Inhibits NLRP3 by acting through receptor EP4 activation that increases cAMP and phosphorylates NLRP3 at serine 295 through PKA. PKA phosphorylation of NLRP3 inhibits the NLRP3 ATPase activity, which is required for assembly of NLRP3-ASC complexes. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic Acid; (-)-Prostaglandin E2; (15S)-Prostaglandin E2; Cervidil; Cerviprime; Cerviprost; Dinoprostone; Minprostin E2; PGE2; Prepidil. Grades: Highly Purified. CAS No. 363-24-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??O?. US Biological Life Sciences. |  Worldwide |
| Prostaglandin E2 ethanolamide | Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 with improved water solubility. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA) and acts as an agonist of E prostanoid (EP) receptors 1-4 with Ki values of 2.45, 0.46, 0.2, and 0.51 μM, respectively. Synonyms: Dinoprostone ethanolamide; PGE2-EA; Prostamide E2; N-(11R,15S-dihydroxy-9-oxo-5Z,13E-prostadienoyl)-ethanolamine; (5Z,11α,13E,15S)-11,15-Dihydroxy-N-(2-hydroxyethyl)-9-oxo-prosta-5,13-dien-1-amide; PGE2 ethanolamide; Prostaglandin E2-EA; N-(2-hydroxyethyl)-9-oxo-11α,15S-dihydroxy-prosta-5Z,13E-dien-1-amide. Grades: ≥98%. CAS No. 194935-38-1. Molecular formula: C22H37NO5. Mole weight: 395.53. | |
| Prostaglandin E2 Ethanolamide-d4 | Prostaglandin E2 Ethanolamide-d4. Group: Biochemicals. Alternative Names: (5Z,11α,13E,15S)-11,15-Dihydroxy-N-(2-hydroxyethyl)-9-oxo-prosta-5,13-dien-1-amide; Prostamide E2; PGE2 ethanolamide. Grades: Highly Purified. Pack Sizes: 50ug. Molecular Formula: C22H33D4NO5, Molecular Weight: 399.56. US Biological Life Sciences. | Worldwide |
| 11-deoxy-16,16-dimethyl prostaglandin E2 | AY 24609 is an analogue of PGE2 and a selective EP2 and EP3 receptors agonist. It also inhibits gastric acid secretion and ulcer formation in rat. Synonyms: AY 24609; 11-deoxy-16,16-dimethyl PGE2; (Z)-7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid. Grades: ≥98%. CAS No. 53658-98-3. Molecular formula: C22H36O4. Mole weight: 364.5. | |
| 11-Deoxy Prostaglandin E2 | 11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC 50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35536-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114910. | |
| 15-keto-Prostaglandin E2 | 15-keto-Prostaglandin E2 is an endogenous metabolite. 15-keto-Prostaglandin E2 inhibits STAT3 activation by binding to its Cys259 residue. 15-keto-Prostaglandin E2 can bind and stabilize EP2 and EP4 receptor. 15-keto-Prostaglandin E2 inhibits breast cancer cell growth and progression. 15-keto-Prostaglandin E2 activates PPAR-γ and promotes fungal growth [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 15-keto-PGE2. CAS No. 26441-05-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113205. | |
| 15-Keto prostaglandin E2 | 15-Keto prostaglandin E2 is a metabolite of PGE2 formed by 15-hydroxy PGDH. Synonyms: 15-keto PGE2; 15-Oxo-PGE2. Grades: ≥95%. CAS No. 26441-05-4. Molecular formula: C20H30O5. Mole weight: 350.5. | |
| 15-Keto Prostaglandin E2 | 15-Keto Prostaglandin E2 is a lipid compound derived from arachidonic acid by the action of cyclooxygenases. Prostaglandins act locally as messenger molecules in a variety of physiological processes. Group: Biochemicals. Grades: Highly Purified. CAS No. 26441-05-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H30O5, Molecular Weight: 350.45. US Biological Life Sciences. | Worldwide |
| 16,16-Dimethyl prostaglandin E2 | 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 16,16-dimethyl PGE2. CAS No. 39746-25-3. Pack Sizes: 5 mg (26.28 mM * 500 μL in Methyl acetate); 10 mg (26.28 mM * 1 mL in Methyl acetate); 25 mg (26.28 mM * 2.5 mL in Methyl acetate); 50 mg (26.28 mM * 5 mL in Methyl acetate); 100 mg (26.28 mM * 10 mL in Methyl acetate). Product ID: HY-106420. | |
| 16,16-Dimethyl Prostaglandin E2 | 16,16-Dimethyl Prostaglandin E2, a prostaglandin E2 derivative, could induce an increase in hematopoietic stem cell (HSC) numbers in mouse model. Uses: Anti-ulcer agents. Synonyms: 16,16-Dimethyl-pge2; 16,16-dimethylprostaglandin E2; 16,16-Dimethyl-prostaglandin E2; dmpge2; (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid. Grades: >98%. CAS No. 39746-25-3. Molecular formula: C22H36O5. Mole weight: 380.52. | |
| 16,16-Dimethyl Prostaglandin E2 | Synthetic derivative of prostaglandin E2. Increases embryonic stem cell (ESC) hematopoietic colony formation in mouse bone marrow. Also induces an increase in hematopoietic stem cell (HSC) numbers and enhances Wnt activity within the HSC population in zebrafish embryos. Group: Biochemicals. Grades: Highly Purified. CAS No. 39746-25-3. Pack Sizes: 1mg. Molecular Formula: C22H36O5. US Biological Life Sciences. | Worldwide |
| 17-Phenyl trinor prostaglandin E2 | 17-Phenyl trinor PGE2 is a synthetic analog of PGE2. It is an EP1 and EP3 receptor agonist. Synonyms: 17-phenyl trinor PGE2; 17-phenyl-trinor-prostaglandin E2. Grades: ≥98%. CAS No. 38315-43-4. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| 17-Phenyl-trinor-prostaglandin E2 | 17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2). Group: Biochemicals. Grades: Highly Purified. CAS No. 38315-43-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H30O5, Molecular Weight: 386.48. US Biological Life Sciences. | Worldwide |
| 17-Phenyl trinor prostaglandin E2 ethyl amide | 17-Phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively). Synonyms: 17-phenyl trinor PGE2 ethyl amide; (Z)-N-ethyl-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]-5-oxocyclopentyl]hept-5-enamide. Grades: ≥98%. CAS No. 1219032-20-8. Molecular formula: C25H35NO4. Mole weight: 413.6. | |
| 19(R)-Hydroxy prostaglandin E2 | 19(R)-Hydroxy-prostaglandin E2 is a PGE2 metabolite that acts as a potent smooth muscle relaxant and a selective EP2 receptor agonist, contrary to PGE2, which can activate a variety of prostanoid receptor types. Synonyms: 19(R)-hydroxy PGE2; 19(R)-OH PGE2; 19(R)-hydroxy Prostaglandin E2. Grades: ≥98%. CAS No. 64625-54-3. Molecular formula: C20H32O6. Mole weight: 368.5. | |
| 19(R)-Hydroxy-prostaglandin E2 | 19(R)-hydroxy Prostaglandin E2 is a selective EP2 receptor agonist and a smooth muscle relaxant (1,2). Group: Biochemicals. Grades: Highly Purified. CAS No. 64625-54-3. Pack Sizes: 50ug, 100ug. Molecular Formula: C20H32O6, Molecular Weight: 368.46. US Biological Life Sciences. | Worldwide |
| Alprostadil (Prostaglandin E1) EP Impurity G (Prostaglandin E2) | Alprostadil (Prostaglandin E1) EP Impurity G (Prostaglandin E2). Uses: For analytical and research use. Group: Impurity standards. CAS No. 363-24-6. Molecular Formula: C20H32O5. Mole Weight: 352.47. Catalog: APB363246. |  |
| prostaglandin-E2 9-reductase | Reduces prostaglandin E2 to prostaglandin F2&alpha. A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds. May be identical with EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+). Group: Enzymes. Synonyms: PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Enzyme Commission Number: EC 1.1.1.189. CAS No. 42613-35-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0091; prostaglandin-E2 9-reductase; EC 1.1.1.189; 42613-35-4; PGE2-9-OR; reductase, 15-hydroxy-9-oxoprostaglandin; 9-keto-prostaglandin E2 reductase; 9-ketoprostaglandin reductase; PGE-9-ketoreductase; PGE2 9-oxoreductase; PGE2-9-ketoreductase; prostaglandin 9-ketoreductase; prostaglandin E 9-ketoreductase; prostaglandin E2-9-oxoreductase. Cat No: EXWM-0091. |  |
| 15-hydroxyprostaglandin dehydrogenase (NAD+) | Acts on prostaglandin E2, F2α and B1, but not on prostaglandin D2. cf. EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+) and EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+). Group: Enzymes. Synonyms: NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I); PGDH; 11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase; 15-OH-PGDH; 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostanoic dehydrogenase; NAD+-specific 15-hydroxyprostaglandin dehydrogenase; prostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NAD+); (5Z,13E)-(15S)-11α,15-dihydroxy-9-oxoprost-13. Enzyme Commission Number: EC 1.1.1.141. CAS No. 9030-87-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0045; 15-hydroxyprostaglandin dehydrogenase (NAD+); EC 1.1.1.141; 9030-87-9; NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (type I); PGDH; 11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase; 15-OH-PGDH; 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostanoic dehydrogenase; NAD+-specific 15-hydroxyprostaglandin dehydrogenase; prostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NAD+); (5Z,13E)-(15S)-11α,15-dihydroxy-9-oxoprost-13-enoate:NAD+ 15-oxidoreductase. Cat No: EXWM-0045. | |
| 15-hydroxyprostaglandin dehydrogenase (NADP+) | Acts on prostaglandins E2, F2α and B1, but not on prostaglandin D2 [cf. EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) and EC 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)]. May be identical with EC 1.1.1.189 prostaglandin-E2 9-reductase. Group: Enzymes. Synonyms: NADP-dependent 15-hydroxyprostaglandin dehydrogenase; NADP-linked 15-hydroxyprostaglandin dehydrogenase; NADP-specific 15-hydroxyprostaglandin dehydrogenase; type II 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NADP). Enzyme Commission Number: EC 1.1.1.197. CAS No. 54989-39-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0100; 15-hydroxyprostaglandin dehydrogenase (NADP+); EC 1.1.1.197; 54989-39-8; NADP-dependent 15-hydroxyprostaglandin dehydrogenase; NADP-linked 15-hydroxyprostaglandin dehydrogenase; NADP-specific 15-hydroxyprostaglandin dehydrogenase; type II 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase (NADP). Cat No: EXWM-0100. | |
| 2-Amino-4-(1-naphthyl)thiazole | 2-Amino-4-(1-naphthyl)thiazole is a reagent used in the synthesis of 2-substituted ethenesulfonic acid ester derivatives as PTP1B inhibitors. Also used as a reagent in the preparation of pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors for the treatment of inflammation and various cancers. Group: Biochemicals. Grades: Highly Purified. CAS No. 56503-96-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H10N2S, Molecular Weight: 226.3. US Biological Life Sciences. | Worldwide |
| 2-Amino-4-chlorobenzenethiol | 2-Amino-4-chlorobenzenethiol is used as reagent in the synthesis of several organic compounds including that of MHY908 which is an inhibitor of melanogenesis and can potentially be used in the prevention and treatment of pigmentation disorders. Also used in the synthesis of γ-lactam analogs of prostaglandin E2 which may act as EP4 agonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 1004-00-8. Pack Sizes: 5g, 10g. Molecular Formula: C6H6ClNS. US Biological Life Sciences. | Worldwide |
| 2-Formyl-1,1'-biphenyl | 2-Formyl-1,1'-biphenyl is a reactant used in the preparation of imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Formyl-1,1'-biphenyl is also used in the preparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin. Group: Biochemicals. Alternative Names: 2-Formylbiphenyl; 2-Phenylbenzaldehyde; 2-Biphenylcarboxalde hyde; [1,1'-Biphenyl]-2-carboxaldehyde. Grades: Highly Purified. CAS No. 1203-68-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 2-Formyl-1,1'-biphenyl-13C6 | 2-Formyl-1,1'-biphenyl-13C6 is a reactant used in the preparation of labelled imidazoquinoline derivatives, a class of microsomal prostaglandin E2 synthase-1 inhibitors. 2-Formyl-1,1'-biphenyl is also used in the preparation of phenoxybenzylamino carboline derivatives as potential antitumor drugs targeting α-tubulin. Group: Biochemicals. Alternative Names: 2-Formylbiphenyl-13C6; 2-Phenylbenzaldehyde-13C6; 2-Biphenylcarboxaldehyde-13C6; [1,1'-Biphenyl]-2-carboxaldehyde-13C6. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 2-Iodobenzotrifluoride | 2-Iodobenzotrifluoride acts as a reagent in the preparation, cyclooxygenase-1 inhibitory activity, and docking studies of aminoalkoxyphenyl benzamide s. Prepartion and SAR of tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 444-29-1. Pack Sizes: 1g, 5g. Molecular Formula: C7H4F3I, Molecular Weight: 272.01. US Biological Life Sciences. | Worldwide |
| 4',5'-Dihydro-8-Hydroxy Psoralen | 4',5'-Dihydro-8-hydroxypsoralen is a furancouramin with inhibitory activity on CYP3A4 as well as inhibitory effects on prostaglandin E2 production. 4',5'-Dihydro-8-hydroxypsoralen is an impurity of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 2,3-Dihydro-6,7-dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 2,3-Dihydroxanthotoxol. Grades: Highly Purified. CAS No. 68123-30-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-Heptenoic acid,7-[(1r,3as,7as)-4-butyloctahydro-2,5-dioxo-1H-inden-1-yl]-,(5Z)- | Heterocyclic Organic Compound. Alternative Names: BICYCLO PROSTAGLANDIN E2;11-DEOXY-13,14-DIHYDRO-15-KETO-11BETA,16CHI-CYCLOPROSTAGLANDIN E2;(Z)-7-[(2,5-Dioxo-4-butyloctahydro-1H-inden)-1-yl]-5-heptenoic acid. CAS No. 109826-53-1. Molecular formula: C20H30O4. Mole weight: 334.45. Purity: 0.96. IUPACName: (Z)-7-[(1R,3aS,7aS)-4-butyl-2,5-dioxo-3,3a,4,6,7,7a-hexahydro-1H-inden-1-yl]hept-5-enoicacid. Canonical SMILES: CCCCC1C2CC (=O)C (C2CCC1=O)CC=CCCCC (=O)O. Catalog: ACM109826531. |  |
| AAT-008 | AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Synonyms: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. Grades: ≥98%. CAS No. 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8. | |
| APHS | APHS is a specific and covalent COX-2 inhibitor with neuroprotective effects. COX-2 is a prostaglandin (PG) synthetase overexpressed in colorectal cancer (CRC) and has pleiotropic cancer-promoting effects. APHS modifies COX-2 by acetylating the active site (serine 516), thereby inhibiting prostaglandin production. The neuroprotective activity of APHS is inhibited by prostaglandin E2. APHS also co-inhibits the WNT pathway, an anti-tumor mechanism in addition to COX-2 inhibition [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 209125-28-0. Pack Sizes: 1 mg (38.11 mM * 100 μL in Methyl acetate); 5 mg (38.11 mM * 500 μL in Methyl acetate); 10 mg (38.11 mM * 1 mL in Methyl acetate). Product ID: HY-129284. | |
| AX 048 | Ethyl 4-[(2-oxohexadecanoyl)amino]butanoate (AX 048) is a PLA2 (Phospholipase A2) and PGE2 (Prostaglandin E2) inhibitor. PLA2 is known as calcium-dependent cytosolic PLA2 (cPLA2), which selectively releases arachidonic acid from membrane phospholipids. It plays a central role in initiating the synthesis of prostaglandins and leukotrienes. This compound also contains a specific affinity for group IVA cPLA2 which moderates antihyperalgesia effects. Synonyms: AX-048; AX 048; Butanoic acid, 4-((1,2-dioxohexadecyl)amino)-, ethyl ester; UNII-8782Z45DLV; 8782Z45DLV; Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester; ethyl 4-(2-oxohexadecanoylamino)butanoate; ethyl 4-(2-oxohexadecanamido)butanoate; CHEMBL574723; SCHEMBL4781039; DTXSID60236282; AKOS040755666; ethyl 4-[(2-oxohexadecanoyl)amino] butanoate; Q27269809; 4- [(1, 2- dioxohexadecyl)amino]- butanoic acid, ethyl ester. Grades: ≥98%. CAS No. 873079-69-7. Molecular formula: C22H41NO4. Mole weight: 383.6. | |
| Bromelain | Bromelain is an anti-inflammatory agent derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX -pathway [1]. Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-00-7. Pack Sizes: 100 mg. Product ID: HY-129611. | |
| Canniprene | Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa , is a potent inhibitor of 5-lipoxygenase ( 5-LO ) activity ( IC 50 =0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase ( PGE 2 ; IC 50 =10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins [1]. Uses: Scientific research. Group: Natural products. CAS No. 70677-47-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3535. | |
| CAY10580 | Prostaglandin E2 is a naturally occurring prostaglandin which is used as a medication. As a medication it is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It selectively binds the EP4 receptor with Ki of 35 nM. Synonyms: CAY 10580; CAY-10580. Grades: ≥96%. CAS No. 64054-40-6. Molecular formula: C19H35NO4. Mole weight: 341.5. | |
| CAY10684 | Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans. EP4 is a G protein-coupled receptor, which plays important roles in bone formation and resorption. CAY10684 is an EP4 receptor agonist. It displays more than 1,000-fold selectivity for EP4 over other EP receptors. Synonyms: CAY 10684; CAY-10684; 7-((2R)-2-((E)-3-(4'-Chloro-2'-methyl-[1,1'-biphenyl]-3-yl)-3-hydroxyprop-1-en-1-yl)-5-oxopyrrolidin-1-yl)heptanoic acid. Grades: ≥98%. CAS No. 493035-81-7. Molecular formula: C27H32ClNO4. Mole weight: 470. | |
| Chebulagic acid | Chebulagic acid is a polyphenol and tannin that has been found in T. chebula and has diverse biological activities. It is an inhibitor of COX-1, COX-2, and 5-lipoxygenase (5-LO; IC50s = 15, 0.92, and 2.1 μM, respectively) as well as α-glucosidase and 15-LO (IC50s = 0.05 and 24.9 μM, respectively). Chebulagic acid inhibit the LPS-induced upregulation of TNF-α and IL-1β in a dose- and time-dependent manner. And it can also inhibit the production of NO, prostaglandin E2 (PGE2), and reactive oxygen species (ROS), and nuclear translocation of NF-κB in RAW 264.7 macrophages in a concentration-dependent manner. Chebulagic acid also show a protective effect against 1-methyl-4-phenylpyridinium (MPP+) - induce cytotoxicity which mimics the pathological symptom of Parkinson's disease. Uses: Topoisomerase i inhibitors. Synonyms: β-D-glucopyranose; Cyclic 3,6-[(1R)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 1-(3,4,5-trihydroxybenzoate); Cyclic 2?2:4?1-ester with (2S)-2-[(3S,4S)-5-carboxy-3,4-dihydro-3,7,8-trihydroxy-2-oxo-2H-1-benzopyran-4-yl]butanedioic acid. Grades: ≥98%. CAS No. 23094-71-5. Molecular formula: C41H30O27. Mole weight: 954.66. | |
| CP-533536 | CP-533536, also called as Evatanepag, a 3-pyridyl sulfonamide compound, demonstrated excellent in vitro potency against prostaglandin E2 (PGE2) (induces local bone formation with EC50= 0.3 nM) and selectivity against a broad panel of other targets. Synonyms: 2- [3- [ [ (4-tert-butylphenyl) methyl-pyridin-3-ylsulfonylamino] methyl] phenoxy] acetic acid(3-((4-tert-butylbenzyl)-(pyridine-3-sulfonylamino)methyl)phenoxy)acetic acidCP-533536; CP 533536; CP533536; Evatanepag. Grades: 95%. CAS No. 223488-57-1. Molecular formula: C25H28N2O5S. Mole weight: 468.56. | |
| Crisdesalazine | Crisdesalazine (AAD-2004) is an anti-inflammatory agent that simultaneously blocks inflammation mediated by free radicals and prostaglandin E2 (PGE2). Crisdesalazine (AAD-2004) can be used to study neurodegeneration in amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AAD-2004. CAS No. 927685-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105005. | |
| Dehydroevodiamine | Dehydroevodiamine is a major bioactive quinazoline alkaloid isolated from Evodiae Fructus , has an antiarrhythmic effect in guinea-pig ventricular myocytes [1]. Dehydroevodiamine inhibits LPS-induced iNOS , COX-2 , prostaglandin E2 ( PGE2 ) and nuclear factor-kappa B ( NF-κB ) expression in murine macrophage cells [2]. Uses: Scientific research. Group: Natural products. CAS No. 67909-49-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2106. | |
| E7046 | E7046 is an orally bioavailable and specific type 4 prostaglandin E2 (PGE2) receptor EP antagonist (IC50= 13.5 nM) (Ki= 23.14 nM), with anti-tumor activities. Synonyms: E7046; E-7046; E 7046. 4-[(1S)-1-[[3-(difluoromethyl)-1-methyl-5-[3-(trifluoromethyl)phenoxy]pyrazole-4-carbonyl]amino]ethyl]benzoic acid. CAS No. 1369489-71-3. Molecular formula: C22H18F5N3O4. Mole weight: 483.39. | |
| GW2580 | GW2580 is an orally bioavailable inhibitor of cFMS kinase. GW2580 was found to completely inhibit human cFMS kinase in vitro at 0.06 microM and was inactive against 26 other kinases. GW2580 at 1 microM completely inhibited CSF-1-induced growth of mouse M-NFS-60 myeloid cells and human monocytes and completely inhibited bone degradation in cultures of human osteoclasts, rat calvaria, and rat fetal long bone. In contrast, GW2580 did not affect the growth of mouse NS0 lymphoblastoid cells, human endothelial cells, human fibroblasts, or five human tumor cell lines. GW2580 also did not affect lipopolysaccharide (LPS)-induced TNF, IL-6, and prostaglandin E2 production in freshly isolated human monocytes and mouse macrophages. After oral administration, GW2580 blocked the ability of exogenous CSF-1 to increase LPS-induced IL-6 production in mice, inhibited the growth of CSF-1-dependent M-NFS-60 tumor cells in the peritoneal cavity, and diminished the accumulation of macrophages in the peritoneal cavity after thioglycolate injection. Unexpectedly, GW2580 inhibited LPS-induced TNF production in mice, in contrast to effects on monocytes and macrophages in vitro. In conclusion, GW2580's selective inhibition of monocyte growth and bone degradation is consistent with cFMS kinase inhibition. The ability of GW2580 to chronically inhibit CSF-1 signaling through cFMS kinase in normal and tumor cells in vivo makes GW2580 a useful tool in assessing the role of cFMS kinase in normal and disease processes. Synonyms: GW 2580; GW-2580; GW2580. Grades: 0.98. CAS No. 870483-87-7. Molecular formula: C20H22N4O3. Mole weight: 366.421. | |
| GYY-4137 Morpholine salt | GYY-4137 Morpholine salt is a novel water-soluble and slow releasing Hydrogen sulfide(H2S) donor. It protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. It inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. It exhibits potent anti-cancer activity. It exhibits vasodilator and antihypertensive activity in rats, in either the acute or chronic hypertension models. It does not influence vascular smooth muscle cell viability in culture. It also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. Uses: Gyy-4137 morpholine salt inhibits the inflammatory response. it exhibits potent anti-cancer activity. it exhibits vasodilator and antihypertensive activity. Synonyms: GYY4137; GYY-4137; GYY 4137; GYY 4137 morpholine salt; ZYJ1122; ZYJ 1122; ZYJ-1122. GYY4137 Morpholine salt;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;ZYJ1122 morpholine salt;ZYJ-1122 morpholine salt. Grades: ≥95%. CAS No. 106740-09-4. Molecular formula: C15H25N2O3PS2. Mole weight: 376.47. | |
| Mf-63 | Mf-63 is a selective Microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitor. Its IC50 value is 0.9 nM and 1.3 nM for pig mPGES-1 and human mPGES-1 enzyme, respectively. It displays greater than 1,000-fold selectivity over other prostanoid synthases. It strongly inhibited guinea pig mPGES-1 but not the mouse or rat enzyme in rodent species. It did not cause NSAID-like gastrointestinal toxic effects that is caused by non-selective COX inhibitors, although it markedly suppresses PGE2 synthesis in the stomach. It prevents LPS-induced hyperglasia. It has anti-inflammatory, analgesic and anti-cancer agent. Uses: Mf-63 has anti-inflammatory, analgesic and anti-cancer agent. Synonyms: 2-(9-Chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-1,3-benzenedicarbonitrile;2-(6-chloro-1H-phenanthro-[9,10-d]iMidazol-2-yl)isophthalonitrile;MF-63; MF63; MF 63. Grades: >98%. CAS No. 892549-43-8. Molecular formula: C23H11ClN4. Mole weight: 378.81. | |
| Nocistatin (bovine) | Nocistatin (bovine) is a peptide derived from the same precursor as nociceptin, and acts as a negative control of nociceptin. It blocks nociceptin-induced allodynia and hyperalgesia, and attenuates pain evoked by prostaglandin E2. Synonyms: Nocistatin (bovine); 208253-85-4; AKOS024456394; NCGC00167175-01; PD079088. CAS No. 208253-85-4. Molecular formula: C82H135N21O32. Mole weight: 1927.07. | |
| PF 4693627 | PF 4693627 is a potent, selective and orally bioavailable inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) that has the potential to treat inflammation (IC50 value 3 nM and 109 nM in enzyme assay and WHB assay respectively). Uses: Potential treatment of inflammation. Synonyms: PF-4693627; PF 4693627; PF4693627. 1-[5-chloro-6-(4-chlorophenyl)-2-benzoxazolyl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]-4-piperidinecarboxamide. Grades: 99%. CAS No. 1312815-93-2. Molecular formula: C26H29Cl2N3O3. Mole weight: 502.43. | |
| Pirinixic acid aminothiazole | Pirinixic acid aminothiazole is a dual inhibitor of 5-lipoxygenase (5-LO) and microsomal prostaglandin E2 synthase 1 (mPGES-1) with IC50 values of 0.4 and 0.2 μM, respectively. It also weakly inhibits COX-1 and -2. Synonyms: 2-[4-Chloro-6-[4-(2-naphthyl)-2-thiazolylamino]-2-pyrimidinylthio]octanoic acid. Grades: ≥98%. CAS No. 1492060-44-2. Molecular formula: C25H25ClN4O2S2. Mole weight: 513.1. | |
| Proadifen hydrochloride | Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC 50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A ( MAO-A ) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine ( DMT ) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-525A; U-5446; RP-5171. CAS No. 62-68-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1311. | |
| Prosta-5,13-dien-1-oicacid,11,15-dihydroxy-16,16-dimethyl-9-methylene-,monopotassium salt,(5z,11a,13e,15r)-(9ci) | Heterocyclic Organic Compound. Alternative Names: U-46785B;METENPROST POTASSIUM;9-METHYLENE-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID, POTASSIUM SALT;9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT;11,15-Dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-. CAS No. 122576-55-0. Molecular formula: C23H38O4.K. Mole weight: 416.6358. Appearance: A crystalline solid. Purity: 0.96. IUPACName: potassium;(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-methylidenecyclopentyl]hept-5-enoate. Canonical SMILES: CCCCC (C) (C)C (C=CC1C (CC (=C)C1CC=CCCCC (=O)[O-])O)O. [K+]. Density: g/cm³. Catalog: ACM122576550. | |
| Prostaglandin EP2 Receptor Antagonist, TG6-10-1 ( (E) -N- (2- (2- (trifluoromethyl) -1H-indol-1-yl) ethyl) -3- (3, 4, 5-trimethoxyphenyl) acrylamide, EP2 Antagonist, TG6-10-1) | A cell-permeable, 3-acryl-acrylamide derivative that acts as a highly potent, selective, and competitive antagonist of prostaglandin E2 receptor (EP2, Kb = 17.8nM). Exhibits about 300-fold selectivity for the EP2 receptor over human EP3, EP4, and IP receptors, about 100- fold selectivity over human EP1, 25-fold selectivity against human FP and TP, and 10-fold selectivity against human DP1 receptors. Does not affect the activity of about 40 enzymes, ion channels, receptors, and neurotransmitters even at higher concentrations (10uM). Shown to significantly reduce the induction of several inflammatory cytokines and chemokines and reduces the opening of blood-brain barrier during neuronal inflammation. Displays good pharmacokinetic properties with a half-life of 1.6 h and brain to plasma ratio of 1.6 in a murine model (5mg/kg i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences. | Worldwide |
| prostaglandin-E synthase | Brings about the opening of the epidioxy bridge. Requires glutathione. Group: Enzymes. Synonyms: prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Enzyme Commission Number: EC 5.3.99.3. CAS No. 52227-79-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5511; prostaglandin-E synthase; EC 5.3.99.3; 52227-79-9; prostaglandin-H2 E-isomerase; endoperoxide isomerase; endoperoxide isomerase; prostaglandin R-prostaglandin E isomerase; prostaglandin endoperoxide E isomerase; PGE isomerase; PGH-PGE isomerase; PGE2 isomerase; prostaglandin endoperoxide E2 isomerase; prostaglandin H-E isomerase. Cat No: EXWM-5511. | |
| Prostaglandin F2α Tromethamine Salt | One of the most biologically studied of the primary prostaglandins. Closely related to Prostaglandin E2 (PGE2) in that both. Group: Biochemicals. Alternative Names: (5Z, 9α, 11α, 13E, 15S)-9, 11, 15-Trihydroxyprosta-5, 13-dien-1-oic Acid 2-Amino-2-(hydroxymethyl)-1,3-propanediol; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-heptenoic Acid Tromethamine; (+)-Prostaglandin F2α Tromethamine; 9α, 11α, 15(S)-Trihydroxy-5-cis-13-trans-prostadienoic Acid Tromethamine; 9α,11α-PGF2 Tromethamine; 9α,11α-PGF2α Tromethamine; Prostaglandin F2α-tham; THAM PGF2α; Tromethamine Prostaglandin F2α; U 14583E; U 14585. Grades: Highly Purified. CAS No. 38562-01-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| prostamide/prostaglandin F2α synthase | The enzyme contains a thioredoxin-type disulfide as a catalytic group. Prostamide H2 and prostaglandin H2 are the best substrates; the latter is converted to prostaglandin F2&alpha. The enzyme also reduces tert-butyl hydroperoxide, cumene hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. Group: Enzymes. Synonyms: prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Enzyme Commission Number: EC 1.11.1.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0502; prostamide/prostaglandin F2α synthase; EC 1.11.1.20; prostamide/PGF synthase; prostamide F synthase; prostamide/prostaglandin F synthase; tPGF synthase. Cat No: EXWM-0502. | |
| (R)-Butaprost | Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Butaprost has frequently been used to pharmacologically define the EP receptor expression profile of various human and animal tissues and cells. Synonyms: (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester; 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1 methyl ester; TR 4978; 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid methyl ester. Grades: ≥98%. CAS No. 69648-38-0. Molecular formula: C24H40O5. Mole weight: 408.6. | |
| (R)-Butaprost (free acid) | Butaprost is a structural analog of prostaglandin E2 (PGE2) with good selectivity for the EP2 receptor subtype. Synonyms: (±)-15-deoxy-16R-hydroxy-17-cyclobutyl PGE1; 15-deoxy-16R-hydroxy-17-cyclobutyl PGE1; 9-oxo-11α,16R-dihydroxy-17-cyclobutyl-prost-13E-en-1-oic acid. Grades: ≥98%. CAS No. 215168-33-5. Molecular formula: C23H38O5. Mole weight: 394.6. | |
| SC-51089 | A selective EP1 prostanoid receptor antagonist that attenuates prostaglandin E2-induced neuronal cell death in vitro and slows tumor growth in vivo. Its neuroprotective effect may potentially have therapeutic application in human stroke. Group: Biochemicals. Alternative Names: 8-Chloro-dibenz[b, f][1, 4]oxazepine-10(11H)-carboxylic Acid 2-[1-Oxo-3- (4-pyridinyl) propyl]hydrazide Hydrochloride; SC 51089. Grades: Highly Purified. CAS No. 146033-02-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Sulprostone | Sulprostone (SHB 286) is a potent and selective EP3 receptor agonist. Sulprostone (SHB 286) is a prostaglandin E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for the research of pregnancy termination and hemorrhages during delivery [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHB 286; CP-34089; ZK-57671. CAS No. 60325-46-4. Pack Sizes: 1 mg (10.74 mM * 200 μL in Methyl acetate). Product ID: HY-19360. | |
| TG6-10-1 | TG6-10-1, a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2, has been shown antagonist activity at human EP2 receptor expressed in rat C6 cells. It shows low-nanomolar antagonist activity against EP2 (>300-fold selectivity ov. Synonyms: (E)-N-[2-[2-(trifluoromethyl)indol-1-yl]ethyl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamideTG6-10-1; TG 6-10-1; TG-6-10-1; TP6101; TP-6101; TP 6101. CHEMBL32642041415716-58-3C23H23F3N2O4BDBM50016950AKOS0274399 55CS-4637; AK-499428; HY-16978; CS 4637; AK 499428; HY 16978; CS4637; AK499428; HY16978(E)-N-(2-(2-(Trifluoromethyl)-1H-indol-1-yl)ethyl)-3-(3,4,5-trime. CAS No. 1415716-58-3. Molecular formula: C23H23F3N2O4. Mole weight: 448.43. | |
| Tylvalosin | Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Synonyms: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. Grades: ≥95%. CAS No. 63409-12-1. Molecular formula: C53H87NO19. Mole weight: 1042.25. | |
| URB937 | URB937 is a potent, peripheral fatty acid amide hydrolase (FAAH) inhibitor with IC50 value of 26.8 nM. It was shown to reduce prostaglandin E2-induced bladder overactivity and hyperactivity of bladder mechano-afferent nerve fibers in rats. Synonyms: URB-937; URB 937; [3-(3-carbamoylphenyl)-4-hydroxyphenyl] N-cyclohexylcarbamate. Grades: ≥95%. CAS No. 1357160-72-5. Molecular formula: C20H22N2O4. Mole weight: 354.4. | |
| Viridicatol | Viridicatol is a fungal metabolite found in various Penicillium species as well as Phoma. It suppresses the expression of COX-2 and inducible nitric oxide synthase (iNOS) and inhibits production of nitric oxide and prostaglandin E2 (PGE2) in LPS-stimulated RAW 264.7 and BV2 cells. Synonyms: 2(1H)-Quinolinone, 3-hydroxy-4-(3-hydroxyphenyl)-; Carbostyril, 3-hydroxy-4-(m-hydroxyphenyl)-; 3-hydroxy-4-(3-hydroxyphenyl)carbostyril; 4-(3-Hydroxyphenyl)-2,3-quinolinediol. Grades: ≥95%. CAS No. 14484-44-7. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
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