Proteolytic Enzyme Suppliers USA
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Product | Description | |
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?Aminocaproic acid Quick inquiry Where to buy Suppliers range | Aminocaproic acid is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis. Uses: Antifibrinolytic agents. Synonyms: Aminocaproic acid; NSC 400230; NSC-400230; NSC400230. Grades: >98%. CAS No. 60-32-2. Molecular formula: C6H13NO2. Mole weight: 131.17. | |
Aprotinin Quick inquiry Where to buy Suppliers range | Aprotinin is the small protein bovine pancreatic trypsin inhibitor (BPTI). It is an antifibrinolytic molecule that inhibits trypsin and related proteolytic enzymes. It is a competitive serine protease inhibitor which blocks the active sites of enzyme by forming stable complexes with. It is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges. It is used as a medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. It is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. It is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. It was temporarily withdrawn worldwide in 2007. It was reverted its previous standpoint regarding aprotinin by the European Medicines Agency (EMA) scientific committee in February 2012. Uses: Aprotinin is used as medication administered by injection to reduce bleeding during complex surgery, such as heart and liver surgery. it is used clinically to prevent postoperative blood loss and reduce transfusion requirements in those procedures which employ extracorporeal circulation. it is also used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest. Synonyms: H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH; EC: 3.4.21.9; Iniprol; Trasylol; Trazinin; Zymofren; Riker 52G. Grades: >99%. CAS No. 9087-70-1. Molecular formula: C284H432N84O79S7. Mole weight: 6511.48. | |
Bradykinin 1-5 Quick inquiry Where to buy Suppliers range | Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE). Uses: Peptide Inhibitors. CAS No. 23815-89-6. Product ID: R1247. | |
Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 Quick inquiry Where to buy Suppliers range | Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2, a peptide utilized for biological research, is an exemplary agent for evaluating proteolytic activity and inhibitor effects. Notably, its potential in disease treatment, encompassing cancer and inflammation, has put it at the forefront of therapeutic development. In addition to its promising therapeutic properties, Dnp-Pro-Leu-Gly-Leu-Trp-Ala-DArg-NH2 may serve as a vital diagnostic tool for identifying pertinent enzymes within biological samples, providing otherwise unattainable insights for investigative purposes. Synonyms: N-(2,4-DINITROPHENYL)-PRO-LEU-GLY-LEU-TRP-ALA-D-ARG AMIDE; MMP SUBSTRATE, FLUOROGENIC; 360 MMP FRET SUBSTRATE I; DNP-PRO-LEU-GLY-LEU-TRP-ALA-D-ARG-NH2; DNP-PLGLWAR-NH2; N-(2,4-dinitrophenyl)-pro-leu-gly-leu-*trp-ala-D-. Grades: 98%. CAS No. 121282-17-5. Molecular formula: C45H64N14O11. Mole weight: 977.08. | |
DUB Inhibitor IV, b-AP15 (NSC687852, 3, 5-bis ( (4-Nitrophenyl) methylidene) -1-prop-2-enoylpiperidin-4-one, (3E, 5E) -1-Acryloyl-3, 5-bis (4-nitrobenzylidene) piperidin-4-one, USP14 Inhibitor III, UCH-L5/UCH37 Inhibitor II) Quick inquiry Where to buy Suppliers range | A cell-permeable bis-nitrobenzylidene-piperidinone compound that acts as a potent, reversible and selective inhibitor of 19S regulatory-particle-associated deubiquitylating enzymes (DUBs) UCH-L5 and USP-14 (IC50=2.1uM against Ub-AMC substrate), with no effect on UCH-L1, UCH-L3, USP2, USP7, USP8 and BAP1 and on the proteasomal proteolytic activities. Shown to prevent proteasomal degradation (IC50=0.8uM in MelJuSo-UbG76V-YFP cells), and cause accumulation of higher molecular weights polyubiquitinated proteins in HCT-116 cells. Preferentially induces cell-cycle arrest and apoptosis in several colon cancer and in CNS cells, and effectively suppresses tumor growth in various mouse model (5mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. CAS No. 1009817-63-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?, Molecular Weight: 419.4. US Biological Life Sciences. | Worldwide |
Glutaryl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride Quick inquiry Where to buy Suppliers range | Glutaryl-glycyl-L-arginine 7-amido-4-methylcoumarin hydrochloride is an innovative biomedical compound, used for ground-breaking proteolytic enzyme research and development. Fortified by its hydrochloride configuration, it manifests enhanced solubility and unprecedented stability. Synonyms: Glutaryl-Gly-Arg-AMC.HCl. CAS No. 103213-40-7. Molecular formula: C23H31ClN6O7. Mole weight: 538.98. | |
Nα-Benzoyl-L-arginine 4-nitroanilide hydrochloride Quick inquiry Where to buy Suppliers range | A chromogenic substrate for trypsin, papain & other proteolytic enzymes. Synonyms: Bz-L-Arg-pNA HCl; N-[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]benzamide hydrochloride; L-BAPA,L-BAPNA,BANI; Nalpha-Benzoyl-L-arginine 4-nitroanilide hydrochloride; BANI; L-BAPNA. Grades: ≥ 98% (HPLC). CAS No. 21653-40-7. Molecular formula: C19H22N6O4·HCl. Mole weight: 434.90. | |
trans-L-4-Hydroxyproline 4-nitroanilide hydrochloride Quick inquiry Where to buy Suppliers range | Substrate for non-specific proteolytic enzymes. Synonyms: L-Hyp-pNA HCl. Grades: ≥ 99% (Assay by titration, HPLC). CAS No. 213271-05-7. Molecular formula: C11H13N3O4·HCl. Mole weight: 287.74. |