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Protoporphyrin IX Created by the enzyme protoporphyrinogen oxidase, protoporphyrin IX is an important precursor to biologically essential prosthetic groups. Uses: Metabolism of porphyrin. Synonyms: Protoporphyrin; 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid. Grades: ≥95%. CAS No. 553-12-8. Molecular formula: C34H34N4O4. Mole weight: 562.66. BOC Sciences 8
Protoporphyrin IX Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 553-12-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-B1247. MedChemExpress MCE
Protoporphyrin IX Protoporphyrin IX is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls. As a result, a number of organisms are able to synthesize this tetrapyrrole from basic precursors such as glycine and succinyl CoA, or glutamate. Despite the wide range of organisms that synthesize protoporphyrin IX the process is largely conserved from bacteria to mammals with a few distinct exceptions in higher plants.[1][2][3]. Group: Biochemicals. Alternative Names: 3,18-Divinyl-2,7,13,17-tetramethylporphine-8, 12-dipropionic acid. Grades: Reagent Grade. CAS No. 553-12-8. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. USBiological 5
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Protoporphyrin IX cobalt chloride Heterocyclic Organic Compound. Alternative Names: Protoporphyrin IX cobalt chloride;102601-60-5;Co(iII) protoporphyrin ix chloride. CAS No. 102601-60-5. Molecular formula: C34H32ClCoN4O4. Mole weight: 655.037g/mol. IUPACName: 3-[18-(2-carboxyethyl)-7,12-bis(ethenyl)-3,8,13,17-tetramethylporphyrin-21,23-diid-2-yl]propanoic acid;chlorocobalt(2+). Canonical SMILES: CC1=C (C2=CC3=NC (=CC4=C (C (=C ([N-]4)C=C5C (=C (C (=N5)C=C1[N-]2)C)CCC (=O)O)CCC (=O)O)C)C (=C3C)C=C)C=C. Cl[Co+2]. Catalog: ACM102601605. Alfa Chemistry. 3
Protoporphyrin IX-d6 Protoporphyrin IX-d6 is the labeled version of Protoporphyrin IX (CAS: 553-12-8). Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme and PPIX-based strategies have been used for cancer diagnosis and treatment. It can be used in biological study for role of protoporphyrin IX in skin photosensitivity, biliary stones, hepatobiliary damage, liver failure and cancer diagnosis and treatment in human. Group: Biochemicals. Alternative Names: Protoporphyrin IX di-Me Ester-d6; 3,7,12,17-Tetramethyl-8,13-divinyldimethyl Ester 2,18-Porphinedipropionic Acid-d6. Grades: Highly Purified. CAS No. 553-12-8 Unlabeled. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C??H??D?N?O?, Molecular Weight: 596.75. US Biological Life Sciences. USBiological 5
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Cobaltic protoporphyrin ix chloride Heterocyclic Organic Compound. CAS No. 12601-60-5. Molecular formula: C34H32CoN4O4Cl. Mole weight: 655. Catalog: ACM12601605. Alfa Chemistry. 4
Cobalt protoporphyrin ix Cobalt protoporphyrin IX is a potent and specific heme oxygenase-1 (HO-1) inducer. Cobalt protoporphyrin IX exhibits broad-spectrum antiviral activities against Influenza A virus (IAV). Group: Inhibitors. Alternative Names: Cobaltiprotoporphyrin, Cobalt protoporphyrin, Cobalt protoporphyrin IX, cobalt(III) protoporphyrin IX, CID108007, NSC 267101, LS-191353, C007095, 14325-03-2, Cobaltate(2-), (7, 12-diethenyl-3, 8, 13, 17-tetramethyl-21H, 23H-porphine-2, 18-dipropanoato(4-)-kappaN21, kappaN22, kappaN23, kappaN24)-, dihydrogen, (SP-4-2)-, Cobaltate(2-), (7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24)-, dihydrogen, (SP-4-2)-. CAS No. 14325-03-2. Molecular formula: C34H32CoN4O4. Mole weight: 619.575480 [g/mol]. Purity: 0.96. IUPACName: 3-[7,12-bis(ethenyl)-3,8,13,17-tetramethyl-18-(3-oxido-3-oxopropyl)porphyrin-21,23-diid-2-yl]propanoate; cobalt(2+); hydron. Canonical SMILES: CC1=C (CCC ([O-]) =O) C2=CC (C (CCC ([O-]) =O) =C3C) =[N]4C3=CC5=C (C) C (C=C) =C6C=C (C (C) =C7C=C) [N]8=C7C=C1[N-]2[Co+2]84[N-]56. [H+]. [H+]. Catalog: ACM14325032. Alfa Chemistry.
Co(III) protoporphyrin IX chloride Co(III) Protoporphyrin IX chloride (CoPP) is an effective HO-1inducer. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Protoporphyrin IX cobaltic chloride. CAS No. 102601-60-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W250116. MedChemExpress MCE
Cu(II) protoporphyrin IX Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14494-37-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136476B. MedChemExpress MCE
Disodium protoporphyrin ix Disodium protoporphyrin ix. Group: other materials. Alternative Names: OOPORPHYRIN DISODIUM SALT; PROTOPORPHYRIN IX DISODIUM SALT; PROTOPORPHYRIN-IX DISODIUM SALT; PROTOPORPHYRIN DISODIUM; PROTOPORPHYRIN DISODIUM SALT; ZINC IONOPHORE II; 23h-porphine-2,18-dipropanoicacid,7,12-diethenyl-3,8,13,17-tetramethyl-21; disodiumprotoporphyr. CAS No. 50865-01-5. Product ID: disodium 3-[8,13-bis(ethenyl)-3,7,12,17-tetramethyl-18-(3-oxido-3-oxopropyl)-22,23-dihydroporphyrin-2-yl]propanoate. Molecular formula: 606.62. Mole weight: C34< / sub>H32< / sub>N4< / sub>Na2< / sub>O4< / sub>. CC1=C (C2=CC3=C (C (=C (N3)C=C4C (=C (C (=N4)C=C5C (=C (C (=N5)C=C1N2)C)CCC (=O)[O-])CCC (=O)[O-])C)C=C)C)C=C. [Na+]. [Na+]. GPRXGEKBQVXWAQ-UHFFFAOYSA-L. >98.0%(LC). Alfa Chemistry Materials 6
magnesium protoporphyrin IX methyltransferase This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:magnesium-protoporphyrin-IX O-methyltransferase. This enzyme participates in porphyrin and chlorophyll metabolism. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.11. CAS No. 9029-82-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1708; magnesium protoporphyrin IX methyltransferase; EC 2.1.1.11; 9029-82-7. Cat No: EXWM-1708. Creative Enzymes
magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase Requires Fe(II) for activity. The cyclase activity in Chlamydomonas reinhardtii is associated exclusively with the membranes, whereas that from cucumber cotyledons requires both membrane and soluble fractions for activity. Group: Enzymes. Synonyms: Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase. Enzyme Commission Number: EC 1.14.13.81. CAS No. 92353-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0889; magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase; EC 1.14.13.81; 92353-62-3; Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase. Cat No: EXWM-0889. Creative Enzymes
Mn(III) Protoporphyrin IX chloride Dyes. Alternative Names: 5,10,15,20-Tetraphenyl-21H,23H-porphine. CAS No. 120389-54-0. Molecular formula: C34H32ClMnN4O4. Mole weight: 651. Purity: >95%. Catalog: ACM120389540. Alfa Chemistry. 3
N-methyl Protoporphyrin IX N-methyl Protoporphyrin IX is a transition state analog of porphyrin and a potent inhibitor of protoporphyrin IX ferrochelatase involved in heme synthesis. Synonyms: NMPP; N-methyl PPIX; 7,12-Diethenyl-3,8,13,17,23-pentamethyl-21H,23H-porphine-2,18-dipropanoic acid; 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17,22-pentamethyl-23H-porphyrin-2-yl]propanoic acid. Grades: ≥95%. CAS No. 79236-56-9. Molecular formula: C35H36N4O4. Mole weight: 576.7. BOC Sciences 9
protoporphyrinogen IX dehydrogenase (menaquinone) This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments. Group: Enzymes. Synonyms: HemG. Enzyme Commission Number: EC 1.3.5.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1387; protoporphyrinogen IX dehydrogenase (menaquinone); EC 1.3.5.3; HemG. Cat No: EXWM-1387. Creative Enzymes
Tin protoporphyrin IX dichloride Tin protoporphyrin IX dichloride. Group: Biochemicals. Grades: Purified. CAS No. 14325-05-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Tin protoporphyrin IX dichloride Tin protoporphyrin IX dichloride is a potent heme oxygenase inhibitor with selectivity for HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). Tin protoporphyrin IX dichloride is used for the prevention of hyperbilirubinemia in neonates. Synonyms: (OC-6-13)-Dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-stannate(2-) Dihydrogen. CAS No. 14325-05-4. Molecular formula: C34H32Cl2N4O4Sn. Mole weight: 750.25. BOC Sciences 10
Tin protoporphyrin IX dichloride Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX. CAS No. 14325-05-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101194. MedChemExpress MCE
Zinc protoporphyrin IX Zinc protoporphyrin IX. Group: Biochemicals. Grades: Purified. CAS No. 15442-64-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Zinc protoporphyrin IX Zinc protoporphyrin IX is an endogenous metabolite formed during heme biosynthesis and a heme oxygenase inhibitor. Heme oxygenase is the enzyme producing CO, which is an activator of guanylyl cyclase and shares some chemical and biological properties of NO. Zinc protoporphyrin IX has been shown to inactivates the NOS isoforms nNOS, iNOS, and eNOS(IC50 = 0.8, 4, and 5 μM, respectively). Synonyms: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, zinc complex; Zinc protoporphyrin-9; ZnPP; Zinc 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,23-diid-2-yl]propanoic acid; Zn-Protoporphyrin IX. CAS No. 15442-64-5. Molecular formula: C34H32N4O4Zn. Mole weight: 626.03. BOC Sciences 10
Acifluorfen Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50594-66-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-128075. MedChemExpress MCE
Aminolevulinic Acid Aminolevulinic Acid, a topically administered metabolic precursor of protoporphyrin IX, is converted to the photosensitizer protoporphyrin IX (PpIX) after topical administration. It is used as an optical imaging agent. The mechanism of action of aminolevulinic acid is fluorescence contrast activity. Synonyms: 5-amino-4-oxovaleric acid; 5-Aminolevulinate; 5-Aminolevulinic acid; Pentanoic acid, 5-amino-4-oxo-; delta-aminolevulinic acid; Aladerm; Kerastick; Ameluz; delta-ALA; 5-amino-levulinate; 5-ALA; δ-Aminolevulinic Acid. Grades: ≥95%. CAS No. 106-60-5. Molecular formula: C5H9NO3. Mole weight: 131.13. BOC Sciences
Aminolevulinic Acid hydrochloride Aminolevulinic Acid is a topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. It is an intermediate in heme biosynthesis and photochemotherapy for actinic keratosis. Uses: Photochemotherapy for actinic keratosis. Synonyms: Levulan Kerastick; 5-Aminolevulinic acid HCl; 5-ALA; NSC-18509; Gliolan; delta-Aminolevulinic acid hydrochloride. Grades: >98%. CAS No. 5451-9-2. Molecular formula: C5H10ClNO3. Mole weight: 167.59. BOC Sciences
coproporphyrin ferrochelatase The enzyme, present in Gram-positive bacteria, participates in heme biosynthesis. It can also catalyse the reaction of EC 4.99.1.1, protoporphyrin IX ferrochelatase, at a much lower level. Group: Enzymes. Synonyms: hemH (gene name). Enzyme Commission Number: EC 4.99.1.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5366; coproporphyrin ferrochelatase; EC 4.99.1.9; hemH (gene name). Cat No: EXWM-5366. Creative Enzymes
coproporphyrinogen oxidase Coproporphyrinogen oxidase, the sixth enzyme of the haem biosynthetic pathway, converts coproporphyrinogen III to protoporphyrinogen IX through two sequential steps of oxidative decarboxylation. Group: Enzymes. Synonyms: coproporphyrinogen III oxidase; coproporphyrinogenase. Enzyme Commission Number: EC 1.3.3.3. CAS No. 9076-84-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1377; coproporphyrinogen oxidase; EC 1.3.3.3; 9076-84-0; coproporphyrinogen III oxidase; coproporphyrinogenase. Cat No: EXWM-1377. Creative Enzymes
Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate Diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (DDC) inhibits heme production by inhibiting ferrochelatase, the enzyme that catalyzes the addition of Fe2+ to protoporphyrin IX to create heme B. Synonyms: diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Grades: ≥ 98 %. CAS No. 632-93-9. Molecular formula: C14H21NO4. Mole weight: 267.32. BOC Sciences 10
Fomesafen Fomesafen is a type of efficient and selective protoporphyrinogen IX oxidase (PPO) inhibitor. Fomesafen is a herbicide and has the advantages of low toxicity and high selectivity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72178-02-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B2010. MedChemExpress MCE
Hemin Chloride Hemin is an iron-containing porphyrin.[1] More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand. Used in the management of porphyria attacks, particularly in acute intermittent porphyria. Sometimes distinguished from hematin which has a hydroxide ligand in place of the chloride, however, the terms are sometimes equated.[2] Hematin is considered the "X factor" required for the growth of Haemophilus influenzae.[3]. Group: Biochemicals. Alternative Names: Chloro (protoporphyrinato) iron (III) ; Chlorohemin; Chloroprotoporphyrin IX iron(III); Ferriprotoporphyrin IX chloride, Hemin(chloride). Grades: Highly Purified. CAS No. 16009-13-5. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C34H32ClFeN4O4, Molecular Weight: 652. US Biological Life Sciences. USBiological 7
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Hemin Chloride, Porcine Hemin is an iron-containing porphyrin. More specifically, it is protoporphyrin IX containing a ferric iron ion (heme B) with a chloride ligand. Used in the management of porphyria attacks, particularly in acute intermittent porphyria. Sometimes distinguished from hematin which has a hydroxide ligand in place of the chloride, however, the terms are sometimes equated. Hematin is considered the "X factor" required for the growth of Haemophilus influenzae. Group: Biochemicals. Alternative Names: Chloro (protoporphyrinato) iron (III) ; Chlorohemin; Chloroprotoporphyrin IX iron(III); Ferriprotoporphyrin IX chloride, Hemin(chloride). Grades: Molecular Biology Grade. CAS No. 16009-13-5. Pack Sizes: 1g, 5g, 25g. Molecular Formula: C34H32ClFeN4O4, Molecular Weight: 651.94. US Biological Life Sciences. USBiological 5
Worldwide
magnesium chelatase This is the first committed step of chlorophyll biosynthesis and is a branchpoint of two major routes in the tetrapyrrole pathway. Group: Enzymes. Synonyms: protoporphyrin IX magnesium-chelatase; protoporphyrin IX Mg-chelatase; magnesium-protoporphyrin IX chelatase; magnesium-protoporphyrin chelatase; magnesium-chelatase; Mg-chelatase; Mg-protoporphyrin IX magnesio-lyase. Enzyme Commission Number: EC 6.6.1.1. CAS No. 9074-88-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5827; magnesium chelatase; EC 6.6.1.1; 9074-88-8; protoporphyrin IX magnesium-chelatase; protoporphyrin IX Mg-chelatase; magnesium-protoporphyrin IX chelatase; magnesium-protoporphyrin chelatase; magnesium-chelatase; Mg-chelatase; Mg-protoporphyrin IX magnesio-lyase. Cat No: EXWM-5827. Creative Enzymes
Methyl aminolevulinate The methyl ester of 5-aminolevulinic acid. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application (often as the hydrochloride salt) results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. Uses: Photosensitizing agents. Synonyms: Aminolevulinic acid methyl ester; Metvix; methyl 5-aminolevulinate; 5-Aminolevulinic acid methyl ester; Pentanoic acid, 5-amino-4-oxo-, methyl ester. Grades: >98%. CAS No. 33320-16-0. Molecular formula: C6H11NO3. Mole weight: 145.16. BOC Sciences 11
Methyl aminolevulinate hydrochloride Methyl aminolevulinate hydrochloride is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a proagent that can be metabolized to Protoporphyrin IX [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79416-27-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-A0169A. MedChemExpress MCE
Methyl Aminolevulinate Hydrochloride Methyl Aminolevulinate Hydrochloride is the methyl ester of Aminolevulinic Acid, which is a precursor of a photosensitizer and also is used as an add on agent for photodynamic therapy. It shows much higher lipophilicity and highly efficient at inducing protoporphyrin IXproduction in cell culture. Synonyms: Methyl 5-amino-4-oxopentanoate hydrochloride; Methyl 5-Aminolevulinate Hydrochloride; 5-Amino-4-oxopentanoic Acid Methyl Ester Hydrochloride. CAS No. 79416-27-6. Molecular formula: C6H12ClNO3. Mole weight: 181.616. BOC Sciences 8
nitric-oxide synthase (NADPH) Binds FAD, FMN, heme (iron protoporphyrin IX) and tetrahydrobiopterin. This eukaryotic enzyme, which is found in plants and animals, consists of oxygenase and reductase domains that are linked via a regulatory calmodulin-binding domain. Upon calcium-induced calmodulin binding, the reductase and oxygenase domains form a complex, allowing electrons to flow from NADPH via FAD and FMN to the active center. May produce superoxide under certain conditions. cf. EC 1.14.13.165, nitric-oxide synthase [NAD(P)H dependent]. Group: Enzymes. Synonyms: nitric oxide synthetase; endothelium-derived relaxation factor-forming enzyme; endothelium-derived relaxing factor synthase; NO synthase; NADPH-diaphorase. Enzyme Commission Number: EC 1.14.13.39. CAS No. 125978-95-2. NOSs. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0846; nitric-oxide synthase (NADPH); EC 1.14.13.39; 125978-95-2; nitric oxide synthetase; endothelium-derived relaxation factor-forming enzyme; endothelium-derived relaxing factor synthase; NO synthase; NADPH-diaphorase. Cat No: EXWM-0846. Creative Enzymes
nitric-oxide synthase [NAD(P)H] Binds heme (iron protoporphyrin IX) and tetrahydrobiopterin. Most of the bacterial and archaeal enzymes consist of only an oxidase domain and function together with bacterial ferredoxins. The enzyme from the Δ-proteobacterium Sorangium cellulosum also includes a reductase domain that binds FAD, FMN and a [2Fe-2S] cluster. The similar enzymes from plants and animals use only NADPH as acceptor (cf. EC 1.14.13.39). Group: Enzymes. Synonyms: nitric oxide synthetase; NO synthase. Enzyme Commission Number: EC 1.14.13.165. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0764; nitric-oxide synthase [NAD(P)H]; EC 1.14.13.165; nitric oxide synthetase; NO synthase. Cat No: EXWM-0764. Creative Enzymes
protoporphyrinogen oxidase This is the last common enzyme in the biosynthesis of chlorophylls and heme. Two isoenzymes exist in plants: one in plastids and the other in mitochondria. This is the target enzyme of phthalimide-type and diphenylether-type herbicides. The enzyme from oxygen-dependent species contains FAD. Also slowly oxidizes mesoporphyrinogen IX. Group: Enzymes. Synonyms: protoporphyrinogen IX oxidase; protoporphyrinogenase; PPO; Protox; HemG; HemY. Enzyme Commission Number: EC 1.3.3.4. CAS No. 53986-32-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1378; protoporphyrinogen oxidase; EC 1.3.3.4; 53986-32-6; protoporphyrinogen IX oxidase; protoporphyrinogenase; PPO; Protox; HemG; HemY. Cat No: EXWM-1378. Creative Enzymes
Tiafenacil Tiafenacil is a new protoporphyrinogen IX oxidase ( PPO )-inhibiting herbicide, with IC 50 values of 22 to 28 nM for various plant species, including amaranth ( Amaranthus tuberculatus ), soybean ( Glycine max ), arabidopsis ( Arabidopsis thaliana ), and rapeseed ( Brassica napus ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1220411-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137551. MedChemExpress MCE
Zinc Protoporphyrin Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H 2 O 2 [1]. Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration [2]. Zinc Protoporphyrin has anti-cancer activity [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9. CAS No. 15442-64-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101193. MedChemExpress MCE

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