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| Product | Description | |
|---|---|---|
| Psoralen | Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ficusin. CAS No. 66-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0053. |  |
| Psoralen | Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al. Group: Inhibitors. Alternative Names: 2-Propenoicacid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone. CAS No. 66-97-7. Molecular formula: C11H6O3. Mole weight: 186.16. Appearance: White powder. Purity: 0.98. IUPACName: Furo[3,2-g]chromen-7-one. Canonical SMILES: C1=CC(=O)OC2=CC3=C(C=CO3)C=C21. Density: 1.25 g/ml. Catalog: ACM66977. |  |
| Psoralen | Psoralen. Group: Biochemicals. Grades: Highly Purified. CAS No. 66-97-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H6O3. US Biological Life Sciences. |  Worldwide |
| Psoralen (7H-Furo[3,2-g][1]benzopyran-7-one, Furo[3,2-g]coumarin, Ficusin) | Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems. Group: Biochemicals. Alternative Names: 7H-Furo[3,2-g][1]benzopyran-7-one; Furo[3,2-g]coumarin; Ficusin. Grades: Highly Purified. CAS No. 66-97-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H6O3. US Biological Life Sciences. | Worldwide |
| Psoralen Azide | Psoralen Azide is a chemical compound used in biomedical research to study DNA damage and repair pathways. It is commonly used to crosslink DNA and proteins, as well as to label proteins with azide groups for subsequent click chemistry reactions. Synonyms: 4'-Azidomethyl-4,5',8-trimethylpsoralen. Molecular formula: C15H13N3O3. Mole weight: 283.28. |  |
| Psoralen-c 2 cep | Heterocyclic Organic Compound. Alternative Names: PSORALEN-C 2 CEP. CAS No. 126221-83-8. Molecular formula: C26H35N2O6P. Mole weight: 502.54. Purity: 0.96. IUPACName: PSORALEN-C 2 CEP. Catalog: ACM126221838. | |
| Psoralen-C2 CEP | Psoralen-C2 CEP is an innovative biomedical compound, used for studying a myriad of skin afflictions, particularly psoriasand vitiligo. It is derived from psoralen, an organic constituent inherent to select flora. Synonyms: 2-[4'-(hydroxymethyl)-4,5',8-trimethylpsoralen]-ethyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Psoralen C2 Phosphoramidite. Grades: 95%. CAS No. 126221-83-8. Molecular formula: C26H35N2O6P. Mole weight: 502.55. | |
| Psoralen C6 Phosphoramidite | Psoralen C6 Phosphoramidite is an indispensable compound, finding extensive employment in DNA synthesis and modification. This remarkable product effectively facilitates the incorporation of psoralen derivatives into oligonucleotides, thereby enabling the research of an extensive array of afflictions encompassing cancer and dermatological conditions. Synonyms: 6-[4'-(Hydroxymethyl)-4,5',8-trimethylpsoralen]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester. CAS No. 518046-08-7. Molecular formula: C30H43N2O6P. Mole weight: 558.65. | |
| psoralen synthase | This microsomal cytochrome P-450-dependent enzyme is specific for (+)-marmesin, and to a much lesser extent 5-hydroxymarmesin, as substrate. Furanocoumarins protect plants from fungal invasion and herbivore attack. (+)-Columbianetin, the angular furanocoumarin analogue of the linear furanocoumarin (+)-marmesin, is not a substrate for the enzyme but it is a competitive inhibitor. Group: Enzymes. Synonyms: CYP71AJ1. Enzyme Commission Number: EC 1.14.13.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0701; psoralen synthase; EC 1.14.13.102; CYP71AJ1. Cat No: EXWM-0701. |  |
| 4',5'-Dihydro-8-Hydroxy Psoralen | 4',5'-Dihydro-8-hydroxypsoralen is a furancouramin with inhibitory activity on CYP3A4 as well as inhibitory effects on prostaglandin E2 production. 4',5'-Dihydro-8-hydroxypsoralen is an impurity of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 2,3-Dihydro-6,7-dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 2,3-Dihydroxanthotoxol. Grades: Highly Purified. CAS No. 68123-30-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4',5'-Dihydro-8-methoxy Psoralen | 4',5'-Dihydro-8-methoxypsoralen is a furocouramin derivative with insect antifeeding activity. 4',5'-Dihydro-8-methoxypsoralen is dihydro impurity as well as a metabolite of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;2,3-Dihydro-6-hydroxy-7-methoxy-5-benzofuranacrylic Acid δ-Lactone; 4',5'-Dihydro-8-methoxypsoralen; 9-Methoxy-2,3-dihydrofuro[3,2-g]coumarin; NSC 401281. Grades: Highly Purified. CAS No. 3779-3-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-(4-Phenoxybutoxy)psoralen | 5-(4-Phenoxybutoxy)psoralen is selective inhibitor of Kv1.3, voltage-gated K+ channel. It potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. It has 23-fold selectivity for Kv1.3 over Kv1.5. It is used in treatment of multiple sclerosis. It was developed by Airmid company and is in Cilinic phase 1. Uses: 5-(4-phenoxybutoxy)psoralen is used in treatment of multiple sclerosis. Synonyms: SPS-4251; SPS 4251; SPS4251; AS-77; PAP-1; AS 77; PAP 1; AS77; PAP1; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)-;4-(4-Phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one;2-g][1]benzopyran-7-one;4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one. Grades: 95%. CAS No. 870653-45-5. Molecular formula: C21H18O5. Mole weight: 350.36. | |
| 8-Allyloxy-4,9-dimethyl psoralen | 8-Allyloxy-4,9-dimethyl psoralen. Group: Biochemicals. Alternative Names: 3,5-Dimethyl-9-(2-propen-1-yloxy)-7H-furo[3,2-g][1]benzopyran-7-one. Grades: Highly Purified. CAS No. 1241916-83-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H14O4. US Biological Life Sciences. | Worldwide |
| Bergapten (4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 5-Methoxypsoralen, Bergaptan, Bergaptene, Heraclin, Majudin,5-MOP, Psoraderm-5) | Naturally occurring analog of psoralen and isomer of methoxsalen. Found in a wide variety of plants. Antipsoriatic. Group: Biochemicals. Alternative Names: 4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 5-Methoxypsoralen; Bergaptan; Bergaptene; Heraclin; Majudin;5-MOP, Psoraderm-5. Grades: Highly Purified. CAS No. 484-20-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| (+)-Biotin-(PEO)4-psoralen | (+)-Biotin-(PEO)4-psoralen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| (+)-Biotin-(PEO)4-psoralen 99+% (NMR) | (+)-Biotin-(PEO)4-psoralen 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Methoxsalen (9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 8-Methoxypsoralen, Xanthotoxin, 8-MOP, Meladinine, Oxsoralen) | Naturally occurring analog of psoralen. Use in treatment of psoriasis and mycosis fungoides. Group: Biochemicals. Alternative Names: 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 8-Methoxypsoralen; Xanthotoxin;8-MOP; Meladinine; Oxsoralen. Grades: Highly Purified. CAS No. 298-81-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Succinimidyl-[4-(psoralen-8-yloxy)]butyrate | Succinimidyl-[4-(psoralen-8-yloxy)]butyrate. Group: Biochemicals. Alternative Names: Spb. Grades: Highly Purified. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR) | Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 6-(Carboxymethyl)-7-hydroxy-8-methoxy Coumarin | The major metabolite of 8-Methoxy Psoralen. Group: Biochemicals. Alternative Names: 7-Hydroxy-8-methoxy-2-oxo-2H-1-benzopyran-6-acetic Acid; 6-(7-Hydroxy-8-methoxycoumaryl)acetic Acid. Grades: Highly Purified. CAS No. 71942-06-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Acitretin sodium | Acitretin sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin sodium as a monotherapy for plaque psoriasis is less, although it is often used in combination therapy with other systemic psoriasis therapies, especially ultraviolet B or psoralen plus ultraviolet A phototherapy, to increase efficacy. Such combination treatments may potentially minimise toxicity by using lower doses of each of the two agent. Synonyms: Ro 10-1670 sodium; Soriatane sodium. Grades: >98%. CAS No. 925701-88-8. Molecular formula: C21H25NaO3. Mole weight: 348.41. | |
| Amotosalen hydrochloride | Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-59. CAS No. 161262-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107004A. | |
| AMT-NHS | AMT-NHS is an RNA-protein crosslinker that can be used to capture different RNA-protein interactions in cells. AMT-NHS consists of a psoralen derivative and an N-hydroxysuccinimide ester group that reacts with the RNA bases and primary amines of proteins, respectively. AMT-NHS can penetrate living yeast cells and cross-link Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different cross-linking patterns and targets both single-stranded and double-stranded regions of RNA. Synonyms: 2,5-dioxopyrrolidin-1-yl 3-(((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl)thio)propanoate. Molecular formula: C22H21NO7S. Mole weight: 443.47. | |
| Angelicin | Angelicin, a furocoumarin naturally occurring tricyclic aromatic compound, structurally related to psoralens, is reported to have anti-cancer, antiviral, anti-inflammatory activity.IC50 value: 49.56 μM (cellular cytotoxicity); 5.39 μg/ml (28.95 μM) (against MHV-68)Target:In vitro: In human SH-SY5Y neuroblastoma cells, angelicin increased cellular cytotoxicity in a dose- and time-dependent manner with IC50 of 49.56 μM at 48 h of incubation. Angelicin dose-dependently downregulated the expression of anti-apoptotic proteins including Bcl-2, Bcl-xL, and Mcl-1; Angelicin-induced apoptosis is mediated primarily through the intrinsic caspase-mediated pathway. Angelicin efficiently inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced lytic replication of human gammaherpresviruses in both EBV- and KSHV-infected cells. Angelicin was potentially advantageous to prevent inflammatory diseases by inhibiting NF-κB and MAPK pathways.In vivo: Group: Inhibitors. CAS No. 523-50-2. Molecular formula: C11H6O3. Mole weight: 186.16. Appearance: Solid. Purity: 0.9986. Canonical SMILES: O=C1C=CC2=CC=C(OC=C3)C3=C2O1. Catalog: ACM523502. | |
| Bakuchiol | Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 ( UGT2B7 ) [2] and human carboxylesterase 2 ( hCE2 ) [3] , with IC 50 s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory [5] , antibacterial [4] , antitumor [1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0235. | |
| Bergaptol | A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 4-Hydroxybergapten; 5-Hydroxy-6,7-furanocoumarin; 5-Hydroxypsoralen; NSC 341958. Grades: Highly Purified. CAS No. 486-60-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Methoxsalen | Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: 8-Methoxypsoralen; Xanthotoxin; 8-MOP. CAS No. 298-81-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-30151. | |
| Trioxsalen | A derivative of psoralen, which intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks. Uses: Photoactive probe. Synonyms: 4,5',8-Trimethylpsoralen;2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one;NSC71047; NSC-71047; NSC 71047; Trioxsalen, trimethylpsoralen, Trioxysalen; Trisoralen. Grades: >98.0%(LC). CAS No. 3902-71-4. Molecular formula: C14H12O3. Mole weight: 228.247. | |
| Trioxsalen | Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trisoralen; Trioxysalen; TMP. CAS No. 3902-71-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1157. | |
| Xanthotoxol | A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities. Group: Biochemicals. Alternative Names: 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 6,7-Dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 3-(6,7-Dihydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone; 8-Hydroxypsoralen; NSC 401269. Grades: Highly Purified. CAS No. 2009-24-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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