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| Product | Description | |
|---|---|---|
| Psoralen | Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ficusin. CAS No. 66-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0053. |  |
| Psoralen | Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Propenoicacid,3-(6-hydroxy-5-benzofuranyl)-,δ-lactone. Product Category: Inhibitors. Appearance: White powder. CAS No. 66-97-7. Molecular formula: C11H6O3. Mole weight: 186.16. Purity: 0.98. IUPACName: Furo[3,2-g]chromen-7-one. Canonical SMILES: C1=CC(=O)OC2=CC3=C(C=CO3)C=C21. Density: 1.25 g/ml. Product ID: ACM66977. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Psoralen | Psoralen. Group: Biochemicals. Grades: Highly Purified. CAS No. 66-97-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H6O3. US Biological Life Sciences. |  Worldwide |
| Psoralen | Psoralen is a photoactive probe that has been used to investigate nucleic acid structure and function. It intercalates into DNA and, when activated by ultraviolet radiation, can create covalent interstrand crosslinks, inducing apoptosis. Synonyms: Ficusin; Furocoumarin. Grade: 97 %. (HPLC). CAS No. 66-97-7. Molecular formula: C11H6O3. Mole weight: 186.16. |  |
| Psoralen (7H-Furo[3,2-g][1]benzopyran-7-one, Furo[3,2-g]coumarin, Ficusin) | Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems. Group: Biochemicals. Alternative Names: 7H-Furo[3,2-g][1]benzopyran-7-one; Furo[3,2-g]coumarin; Ficusin. Grades: Highly Purified. CAS No. 66-97-7. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H6O3. US Biological Life Sciences. | Worldwide |
| psoralen synthase | This microsomal cytochrome P-450-dependent enzyme is specific for (+)-marmesin, and to a much lesser extent 5-hydroxymarmesin, as substrate. Furanocoumarins protect plants from fungal invasion and herbivore attack. (+)-Columbianetin, the angular furanocoumarin analogue of the linear furanocoumarin (+)-marmesin, is not a substrate for the enzyme but it is a competitive inhibitor. Group: Enzymes. Synonyms: CYP71AJ1. Enzyme Commission Number: EC 1.14.13.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0701; psoralen synthase; EC 1.14.13.102; CYP71AJ1. Cat No: EXWM-0701. |  |
| 4',5'-Dihydro-8-Hydroxy Psoralen | 4',5'-Dihydro-8-hydroxypsoralen is a furancouramin with inhibitory activity on CYP3A4 as well as inhibitory effects on prostaglandin E2 production. 4',5'-Dihydro-8-hydroxypsoralen is an impurity of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 2,3-Dihydro-6,7-dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 2,3-Dihydroxanthotoxol. Grades: Highly Purified. CAS No. 68123-30-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4',5'-Dihydro-8-methoxy Psoralen | 4',5'-Dihydro-8-methoxypsoralen is a furocouramin derivative with insect antifeeding activity. 4',5'-Dihydro-8-methoxypsoralen is dihydro impurity as well as a metabolite of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;2,3-Dihydro-6-hydroxy-7-methoxy-5-benzofuranacrylic Acid δ-Lactone; 4',5'-Dihydro-8-methoxypsoralen; 9-Methoxy-2,3-dihydrofuro[3,2-g]coumarin; NSC 401281. Grades: Highly Purified. CAS No. 3779-3-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-(4-Phenoxybutoxy)psoralen | 5-(4-Phenoxybutoxy)psoralen is selective inhibitor of Kv1.3, voltage-gated K+ channel. It potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. It has 23-fold selectivity for Kv1.3 over Kv1.5. It is used in treatment of multiple sclerosis. It was developed by Airmid company and is in Cilinic phase 1. Uses: 5-(4-phenoxybutoxy)psoralen is used in treatment of multiple sclerosis. Synonyms: SPS-4251; SPS 4251; SPS4251; AS-77; PAP-1; AS 77; PAP 1; AS77; PAP1; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)-; 4-(4-Phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one; 2-g][1]benzopyran-7-one; 4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one. Grade: 95%. CAS No. 870653-45-5. Molecular formula: C21H18O5. Mole weight: 350.36. | |
| 5-(4-Phenoxybutoxy)psoralen | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| 8-Allyloxy-4,9-dimethyl psoralen | 8-Allyloxy-4,9-dimethyl psoralen. Group: Biochemicals. Alternative Names: 3,5-Dimethyl-9-(2-propen-1-yloxy)-7H-furo[3,2-g][1]benzopyran-7-one. Grades: Highly Purified. CAS No. 1241916-83-5. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H14O4. US Biological Life Sciences. | Worldwide |
| Bergapten (4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 5-Methoxypsoralen, Bergaptan, Bergaptene, Heraclin, Majudin,5-MOP, Psoraderm-5) | Naturally occurring analog of psoralen and isomer of methoxsalen. Found in a wide variety of plants. Antipsoriatic. Group: Biochemicals. Alternative Names: 4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 5-Methoxypsoralen; Bergaptan; Bergaptene; Heraclin; Majudin;5-MOP, Psoraderm-5. Grades: Highly Purified. CAS No. 484-20-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| (+)-Biotin-(PEO)4-psoralen | (+)-Biotin-(PEO)4-psoralen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| (+)-Biotin-(PEO)4-psoralen 99+% (NMR) | (+)-Biotin-(PEO)4-psoralen 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Methoxsalen (9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 8-Methoxypsoralen, Xanthotoxin, 8-MOP, Meladinine, Oxsoralen) | Naturally occurring analog of psoralen. Use in treatment of psoriasis and mycosis fungoides. Group: Biochemicals. Alternative Names: 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 8-Methoxypsoralen; Xanthotoxin;8-MOP; Meladinine; Oxsoralen. Grades: Highly Purified. CAS No. 298-81-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Succinimidyl-[4-(psoralen-8-yloxy)]butyrate | Succinimidyl-[4-(psoralen-8-yloxy)]butyrate. Group: Biochemicals. Alternative Names: Spb. Grades: Highly Purified. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR) | Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 6-(Carboxymethyl)-7-hydroxy-8-methoxy Coumarin | The major metabolite of 8-Methoxy Psoralen. Group: Biochemicals. Alternative Names: 7-Hydroxy-8-methoxy-2-oxo-2H-1-benzopyran-6-acetic Acid; 6-(7-Hydroxy-8-methoxycoumaryl)acetic Acid. Grades: Highly Purified. CAS No. 71942-06-8. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Acitretin sodium | Acitretin sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin sodium as a monotherapy for plaque psoriasis is less, although it is often used in combination therapy with other systemic psoriasis therapies, especially ultraviolet B or psoralen plus ultraviolet A phototherapy, to increase efficacy. Such combination treatments may potentially minimise toxicity by using lower doses of each of the two agent. Synonyms: Ro 10-1670 sodium; Soriatane sodium. Grade: >98%. CAS No. 925701-88-8. Molecular formula: C21H25NaO3. Mole weight: 348.41. | |
| Amotosalen hydrochloride | Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-59. CAS No. 161262-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107004A. | |
| AMT-NHS | AMT-NHS is an RNA-protein crosslinker. AMT-NHS is composed of a psoralen derivative and an N-hydroxysuccinimide ester group which react with RNA bases and primary amines of protein, respectively. AMT-NHS can penetrate into living yeast cells and crosslink Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different crosslinking patterns and targets both single- and double-stranded regions of RNA. AMT-NHS can be used for capturing diverse RNA-protein interactions in cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2925268-86-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150014. | |
| Angelicin | Angelicin, a furocoumarin naturally occurring tricyclic aromatic compound, structurally related to psoralens, is reported to have anti-cancer, antiviral, anti-inflammatory activity.IC50 value: 49.56 μM (cellular cytotoxicity); 5.39 μg/ml (28.95 μM) (against MHV-68)Target:In vitro: In human SH-SY5Y neuroblastoma cells, angelicin increased cellular cytotoxicity in a dose- and time-dependent manner with IC50 of 49.56 μM at 48 h of incubation. Angelicin dose-dependently downregulated the expression of anti-apoptotic proteins including Bcl-2, Bcl-xL, and Mcl-1; Angelicin-induced apoptosis is mediated primarily through the intrinsic caspase-mediated pathway. Angelicin efficiently inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced lytic replication of human gammaherpresviruses in both EBV- and KSHV-infected cells. Angelicin was potentially advantageous to prevent inflammatory diseases by inhibiting NF-κB and MAPK pathways.In vivo: Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 523-50-2. Molecular formula: C11H6O3. Mole weight: 186.16. Purity: 0.9986. Canonical SMILES: O=C1C=CC2=CC=C(OC=C3)C3=C2O1. Product ID: ACM523502. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bakuchiol | Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 ( UGT2B7 ) [2] and human carboxylesterase 2 ( hCE2 ) [3] , with IC 50 s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory [5] , antibacterial [4] , antitumor [1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0235. | |
| Bergaptol | A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 4-Hydroxybergapten; 5-Hydroxy-6,7-furanocoumarin; 5-Hydroxypsoralen; NSC 341958. Grades: Highly Purified. CAS No. 486-60-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Byakangelicin | Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Synonyms: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-; 9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Biacangelicin; (+)-Byakangelicin; 5-Methoxy-8-(2,3-dihydroxy-3-methylbutoxy)psoralene; Bjacangelicin; Bjakangelicin; Byankagelicine. Grade: >98%. CAS No. 482-25-7. Molecular formula: C17H18O7. Mole weight: 334.32. | |
| Chalepensin | Chalepensin is a furanocoumarin found in several medicinal Rutaceae plants. Chalepensin acts as a cytochrome P450 (P450, CYP) inhibitor that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepensin also exhibits an antimicrobial effect against Streptococcus mutans. Synonyms: Xylotenin; 3-(alpha,alpha-Dimethylallyl)psoralen; 6-(2-methylbut-3-en-2-yl)-7h-furo[3,2-g]chromen-7-one. Grade: 98.0%. CAS No. 13164-03-9. Molecular formula: C16H14O3. Mole weight: 254.285. | |
| Methoxsalen | Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: 8-Methoxypsoralen; Xanthotoxin; 8-MOP. CAS No. 298-81-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-30151. | |
| Methoxsalen-[d3] | Methoxsalen-[d3] is a labelled analogue of 8-Methoxy Psoralen, a naturally occurring analog of Psoralen. Synonyms: Methoxsalen D3. Grade: 95% by HPLC; 95% atom D. CAS No. 80386-99-8. Molecular formula: C12H5D3O4. Mole weight: 219.21. | |
| PAP-1 | PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-(4-Phenoxybutoxy)psoralen. CAS No. 870653-45-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10015. | |
| Trioxsalen | Trioxsalen (Trisoralen), a psoralen derivative, is a photochemical DNA crosslinker. Trioxsalen only works after photoactivation with near ultraviolet light. Trioxsalen is a photosensitizer that can be used for the research of vitiligo and hand eczema. Trioxsalen is used for visualization of genomic interstrand cross-links localized by laser photoactivation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trisoralen; Trioxysalen; TMP. CAS No. 3902-71-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1157. | |
| Xanthotoxol | A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities. Group: Biochemicals. Alternative Names: 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 6,7-Dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 3-(6,7-Dihydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone; 8-Hydroxypsoralen; NSC 401269. Grades: Highly Purified. CAS No. 2009-24-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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