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2-(2-Pyridinyloxy)propanoicAcid is a metabolite of Pyriproxyfen (P998850); a pyridine-based pesticide used against a variety of arthropoda, in particular to protect cotton crops against whitefly. Group: Biochemicals. Grades: Highly Purified. CAS No. 168844-45-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H9NO3, Molecular Weight: 167.16. US Biological Life Sciences.
Worldwide
β-(3-Pyridyl)-D-β-homoglycine
β-(3-Pyridyl)-D-β-homoglycine serves as a good amino-donors in the transamination in the degradation of (S)-β-phenylalanine. Synonyms: H-D-Pyg(3)-(C#CH2)OH; (S)-3-Amino-3-(3-pyridyl)propanoicacid; (3S)-3-amino-3-pyridin-3-ylpropanoicacid; (S)-3-Amino-3-(pyridin-3-yl)propanoicacid; 3-Pyridinepropanoicacid, b-amino-, (bS)-; L-β-Ala-(3-pyridyl)-OH; H-β-Ala-(3-pyridyl)-OH. Grades: ≥ 98% (TLC). CAS No. 129043-04-5. Molecular formula: C8H10N2O2. Mole weight: 166.18.
Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide. Group: Biochemicals. Alternative Names: (αS, βR)-α, β-Dihydroxy-2-pyridinepropanoicAcid Ethyl Ester, 1-Oxide. Grades: Highly Purified. CAS No. 529474-73-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Fmoc-3-amino-L-tyrosine
Fmoc-3-amino-L-tyrosine is an Fmoc protected tyrosine derivative that is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Tyrosine is a very important amino acid - one of the few amino acids which is phosphorylated to vary the physical properties of the peptides, and is a precursor for the formation of iodinated thyroid hormones. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group. Uses: Fmoc-3-amino-l-tyrosine is an fmoc protected tyrosine derivative. Group: Amino acids. Alternative Names: (2S)-3-(3-Amino-4-hydroxyphenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoicacid. CAS No. 726181-70-0. Molecular formula: C24H22N2O5. Mole weight: 418.4. Purity: Peak Area by HPLC ≥95%. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)N[C@@H] (CC4=CC (=C (C=C4)O)N)C (=O)O. Catalog: ACM726181700.
GSK-J2 sodium salt
GSK-J2 is a pyridine regio-isomer of GSK-J1 which poorly inhibits JMJD3 with an IC50 value greater than 100 μM. Synonyms: 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-3-yl)pyrimidin-4-yl)amino)propanoicacid, monosodium salt. Grades: ≥90%. CAS No. 2108665-15-0. Molecular formula: C22H23N5O2·Na. Mole weight: 412.4.
MK-0429
MK-0429 is a potent alpha(nu)beta(3) integrin inhibitor (or αvβ3 inhibitor), which showed therapeutic effects on bone turnover disease in men with hormone-refractory prostate cancer (HRPC) and bone metastases. Clinical trial results showed that MK-0429 was generally well tolerated, with the most common side-effect being nausea. There was some evidence of an early reduction of bone turnover, indicating a potential for clinical use in the treatment of bone mineral density (MBD) although serum PSA was unexpectedly increased during the study. Synonyms: L-000845704; (S)-3-(6-methoxypyridin-3-yl)-3-(2-oxo-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoicacid; NSC776790; 3-Pyridinepropanoicacid, 6-methoxy-β-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]-, (βS)-. Grades: >98%. CAS No. 227963-15-7. Molecular formula: C23H29N5O4. Mole weight: 439.51.
3-(4'-Pyridyl)-D-alanine is a derivative of alanine which is an amino acid that is commonly found in bacteria, such as Streptococcus faecalis. Alanine is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls. D-Alanine is also known to cause cytotoxic oxidative stress in brain tumour cells. Synonyms: D-Ala(4'-pyridyl)-OH; (R)-2-Amino-3-(4'-pyridyl)propanoicacid; D-4-PYRIDYLALANINE; 3-(4-Pyridyl)-D-alanine; (R)-2-Amino-3-(pyridin-4-yl)propanoicacid; (2R)-2-amino-3-(pyridin-4-yl)propanoicacid; BETA-(4-PYRIDYL)-D-ALANINE; D-4-Pal; (2R)-2-amino-3-(4-pyridyl)propanoicacid; 4'-PYRIDYL-D-ALA; H-D-ALA(4-PYRI)-OH. Grades: ≥ 98%. CAS No. 37535-50-5. Molecular formula: C8H10N2O2. Mole weight: 166.18.
3-(4'-Pyridyl)-L-alanine
3-(4-Pyridyl)-L-alanine is a derivative of L-alanine, a non-essential amino acid that can be found naturally in the human body and is obtained by our diet. Synonyms: L-Ala(4'-pyridyl)-OH; (S)-2-Amino-3-(4'-pyridyl)propanoicacid; L-4-PYRIDYLALANINE; 3-(4-Pyridyl)-L-alanine; (S)-2-Amino-3-(pyridin-4-yl)propanoicacid; (2S)-2-amino-3-(pyridin-4-yl)propanoicacid; H-4-Pal-OH; beta-(4-Pyridyl)-L-alanine; H-D-Ala(4-pyridyl)-OH; 4'-Pyridyl-L-Ala; 3-Pyridin-4-ylalanine; H-Ala(4-Pyri)-OH. Grades: ≥ 98%. CAS No. 37535-49-2. Molecular formula: C8H10N2O2. Mole weight: 166.18.
Boc-3-(3'-pyridyl)-D-alanine is an alanine derivative, used in various chemical synthesis and peptide chemistry. Synonyms: Boc-D-Ala(3'-pyridyl)-OH; Boc-(R)-2-amino-3-(3'-pyridyl)propanoicacid; Boc-D-3-Pyridylalanine; BOC-D-3-PAL-OH; Boc-3-(3-pyridyl)-D-alanine; (R)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-3-yl)propanoicacid; BOC-D-3-(3-PYRIDYL)-ALANINE; Boc-D-Pal; N-tert-Butoxycarbonyl-3-pyridyl-D-alanine; Boc D Pal. Grades: ≥ 98% (HPLC). CAS No. 98266-33-2. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Boc-3-(4'-pyridyl)-L-alanine is the protected form of L-Alanine, a non-essential amino acid that can be found naturally in the human body and is obtained by our diet. Synonyms: Boc-L-Ala(4'-pyridyl)-OH; Boc-(S)-2-amino-3-(4'-pyridyl)propanoicacid; Boc-L-4-Pyridylalanine; Boc-Ala(4-pyridyl)-OH; Boc-3-(4-pyridyl)-L-alanine; Boc-4-Pal-Oh; (S)-2-((tert-Butoxycarbonyl)amino)-3-(pyridin-4-yl)propanoicacid; N-(tert-butoxycarbonyl)-3-pyridin-4-yl-L-alanine; Boc-L-3-(4-pyridyl)-alanine. Grades: ≥ 99.5% (Chiral HPLC). CAS No. 37535-57-2. Molecular formula: C13H18N2O4. Mole weight: 266.29.
Clodinafop propargyl
Clodinafop propargyl. Group: Biochemicals. Alternative Names: (2R) -2-[4-[ (5-Chloro-3-fluoro-2-pyridinyl) oxy]phenoxy]propanoicacid 2-propyn-1-yl ester; Prop-2-ynyl (R) -2-[4- (5-chloro-3-fluoropyridin-2-yloxy) phenoxy]propanoate; Topik. Grades: Highly Purified. CAS No. 105512-06-9. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C17H13ClFNO4. US Biological Life Sciences.
Worldwide
Dabigatran Carboxamide
An impurity of Dabigatran. Dabigatran is a very potent anticoagulant, showing that the terminal phenyl can be substituted by the more hydrophilic 2-pyridyl group without substantial loss of activity. Synonyms: 3-(2-(((4-Carbamoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoicAcid; Dabigatran Etexilate Mesylate Impurity D. Grades: ≥95%. CAS No. 2417628-79-4. Molecular formula: C25H24N6O4. Mole weight: 472.49.
Dabigatran Impurity 21
Dabigatran Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(3-amino-4-(methylamino)-N-(pyridin-2-yl)benzamido)propanoicacid. Molecular Formula: C16H18N4O3. Mole Weight: 314.34. Catalog: APB04994.
Dabigatran Impurity 23
Dabigatran Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoicacid. Molecular Formula: C16H16N4O5. Mole Weight: 344.32. Catalog: APB04993.
Dabigatran Impurity 6
Dabigatran Impurity 6 is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: Ethyl 3-(3-Amino-N-(pyridin-2-yl)benzamido)propanoate; 3-[(3-Aminobenzoyl)-pyridin-2-yl-amino] propanoicacid ethyl ester. Molecular formula: C26H25N7O5. Mole weight: 515.53.
Dabigatran Impurity 77
Dabigatran Impurity 77. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-(((4-carbamoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoicacid. CAS No. 2417628-79-4. Molecular Formula: C25H24N6O4. Mole Weight: 472.50. Catalog: APB2417628794.
Dabigatran impurity A
Dabigatran impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoicacid. CAS No. 211914-51-1. Molecular Formula: C25H25N7O3. Mole Weight: 471.51. Catalog: APB211914511.
Dabigatran impurity B
Dabigatran impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3- (2- ( ( (4- (N- ( (hexyloxy) carbonyl) carbamimidoyl) phenyl) amino) methyl) -1-methyl-N- (pyridin-2-yl) -1H-benzo[d]imidazole-5-carboxamido) propanoicacid. CAS No. 212321-78-3. Molecular Formula: C32H37N7O5. Mole Weight: 599.68. Catalog: APB212321783.
Dabigatran impurity F
Dabigatran impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3- (2- ( ( (4- ( ( (hexyloxy) carbonyl) carbamoyl) phenyl) amino) methyl) -1-methyl-N- (pyridin-2-yl) -1H-benzo[d]imidazole-5-carboxamido) propanoicacid. CAS No. 1408238-37-8. Molecular Formula: C32H36N6O6. Mole Weight: 600.66. Catalog: APB1408238378.
Des-(N-PropanoicAcid) (Z)-Hexylcarbamate Dabigatran is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: (Z)-Hexyl (amino (4- ( ( (1-methyl-5- (pyridin-2-ylcarbamoyl) -1H-benzo[d]imidazol-2-yl) methyl) amino) phenyl) methylene) carbamate; Dabigatran Impurity 58. Molecular formula: C29H33N7O3. Mole weight: 527.63.
Fmoc-DL-7-azatryptophan
Peptide synthesis. Group: Amino acids. Alternative Names: 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoicacid. CAS No. 1219143-85-7. Molecular formula: C25H21N3O4. Mole weight: 427.5. Purity: Peak Area by HPLC ≥95%. IUPACName: 2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoicacid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CNC5=C4C=CC=N5)C (=O)O. Density: 1.4±0.1 g/cm3. Catalog: ACM1219143857.
Fmoc-N-Me-3-(4-py)-L-Ala
Fmoc-N-Me-3-(4-py)-L-Ala, a synthetic molecule, finds widespread use in the synthesis of peptides and proteins. Owing to its crucial role as a fundamental building block in solid-phase peptide synthesis, it has emerged as a potent weapon in the battle against numerous human maladies such as cancer and infectious diseases. With versatile functionality and chemical reactivity, the compound facilitates modifications and attachment to the peptide chain, rendering it a prized asset in the biomedical industry and a tool much sought after by researchers. Synonyms: Fmoc-N(Me)4Pal-OH; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(pyridin-4-yl)propanoicacid. CAS No. 2381854-90-4. Molecular formula: C24H22N2O4. Mole weight: 402.4.
GW 1929 hydrochloride
GW 1929 hydrochloride is a selective and orally bioactive agonist of peroxisome proliferator-activated receptor (PPAR)γ (pEC50 = 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors, respectively). GW 1929 causes a decrease of glucose, fatty acid and triglyceride levels following oral administration in vivo. Synonyms: GW 1929 hydrochloride; GW1929 hydrochloride; GW-1929 hydrochloride; N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride; (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoicacid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1217466-21-1. Molecular formula: C30H29N3O4.HCl. Mole weight: 532.03.
Haloxyfop-methyl-d4
Haloxyfop-methyl-d4 is the isotope labelled analog of Haloxyfop-methyl; a herbicide used for selective post-emergence control of annual and perennial grasses in broadleaf crops. Group: Biochemicals. Alternative Names: 2-[4-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]-propanoicAcid Methyl Ester; Dowco 453; Dowco 453ME; Haloxyfop methyl ester; Haloxyfop-Me; Verdict; Verdict R. Grades: Highly Purified. CAS No. Unlabeled: 69806-40-2. Pack Sizes: 5mg, 50mg. Molecular Formula: C??H?D?ClF?NO?, Molecular Weight: 379.75. US Biological Life Sciences.
Worldwide
H-D-3-Pal-OH 2HCl
H-D-3-Pal-OH 2HCl, a synthetic peptide of scientific interest, has the potential to be a promising avenue in the pursuit of new treatments for diseases of varying kinds. Research into the properties of this compound suggests its ability to inhibit cell proliferation and promote apoptosis in oncogenic cells. Interestingly, it may also function as an immunomodulator and possess therapeutic applications towards autoimmune disorders. These findings speak to the complex and multifaceted nature of H-D-3-Pal-OH 2HCl and the implications it could have in furthering scientific understanding of these conditions. Synonyms: (R)-2-Amino-3-(pyridin-3-yl)propanoicacid dihydrochloride; H-D-3-Pal-OH.2HCl; 3-(3-Pyridyl)-D-alanine dihydrochloride. Grades: 95%. CAS No. 93960-21-5. Molecular formula: C8H12Cl2N2O2. Mole weight: 239.10.
H-D-Ala(3-pyridyl)-OH
A reagent used in the synthesis of selective ligands derived from somatostatin antagonists. Synonyms: 3-(3-Pyridyl)-D-alanine; (R)-2-Amino-3-(pyridin-3-yl)propanoicacid. Grades: 95%. CAS No. 70702-47-5. Molecular formula: C8H10N2O2. Mole weight: 166.18.
A pyridinyl -pyrimidinyl aminopropanoicacid that effectively inhibits KDM6 family H3K27m3 demethylases JMJD3 and UTX (IC50 = 18 and 56uM, respectively, by MALDI Mass detection) in an alpha-ketoglutarate-competitive, peptide substrate-non-competitive manner, displaying much reduced potency against JARID1C, JMJD1a, JMJD2a, JMJD2c, JMJD2d, JMJD2e, as well as112 kinases and 60 non-kinase enzymes. Recommended for cell-free assays only. For culture treatment, use the cell-permeable pro-drug GSK-J4. Group: Biochemicals. Grades: Highly Purified. CAS No. 1373422-53-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ibrexafungerp
Ibrexafungerp, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Synonyms: Brexafemme; SCY-078; MK3118; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S, 4aR, 6aS, 7R, 8R, 10aR, 10bR, 12aR, 14R, 15R)-. Grades: ≥95%. CAS No. 1207753-03-4. Molecular formula: C44H67N5O4. Mole weight: 730.03.
Ibrexafungerp Citrate
Ibrexafungerp Citrate, an intravenous and orally bioavailable semisynthetic derivative of enfumafungin, is a triterpene antifungal agent indicated for the treatment of adult and postmenarchal pediatric females with vulvovaginal candidiasis (VVC). It is a glucan synthase inhibitor. Synonyms: Brexafemme Citrate; SCY-078 Citrate; MK-3118 Citrate; 4H-1,4a-Propano-2H-phenanthro[1,2-c]pyran-7-carboxylic acid, 15-[(2R)-2-amino-2,3,3-trimethylbutoxy]-8-[(1R)-1,2-dimethylpropyl]-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-14-[5-(4-pyridinyl)-1H-1,2,4-triazol-1-yl]-, (1S, 4aR, 6aS, 7R, 8R, 10aR, 10bR, 12aR, 14R, 15R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt). CAS No. 1965291-08-0. Molecular formula: C50H75N5O11. Mole weight: 922.17.
Methyl 3-oxo-3-(pyridin-4-yl)propanoate
Methyl 3-oxo-3-(pyridin-4-yl)propanoate. Group: Biochemicals. Alternative Names: 3-Oxo-3-pyridin-4-yl-propionic acid methyl ester. Grades: Highly Purified. CAS No. 829-45-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine
N-Acetyl-S-[4-(2-pyridinyl)benzyl]-L-cysteine is a metabolite of Atazanavir, which is an antiretroviral medication used to treat HIV/AIDS. Synonyms: N-Acetyl-S-(4-(pyridin-2-yl)benzyl)-L-cysteine; L-Cysteine, N-acetyl-S-[[4-(2-pyridinyl)phenyl]methyl]-; (R)-2-acetamido-3-((4-(pyridin-2-yl)benzyl)thio)propanoicacid. Grades: ≥95%. CAS No. 1391068-09-9. Molecular formula: C17H18N2O3S. Mole weight: 330.40.
N-Hydroxydabigatran. Group: Biochemicals. Alternative Names: 3- (2- ( ( (tert-Butoxycarbonyl) (4- (N'-hydroxycarbamimidoyl) phenyl) amino) methyl) -1-methyl-N- (pyridin-2-yl) -1H-benzo[d]imidazole-5-carboxamido) propanoicacid. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
N-Nitroso Dabigatran Impurity 73 Trifluoroacetate
N-Nitroso Dabigatran Impurity 73 Trifluoroacetate is an impurity of Dabigatran, an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Synonyms: ethyl 3- (2- ( ( (4-carbamimidoylphenyl) (nitroso)amino)methyl)-1-methyl-N- (pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate, 2,2,2-trifluoroacetic acid (1:1). Molecular formula: C29H29N8O6F3. Mole weight: 642.59.
PF 00356231
PF 00356231 is a MMP-12 inhibitor, and at high concentrations it also inhibits other MMPs. Synonyms: PF 00356231; PF00356231; PF-00356231; (3R)-3-phenyl-3-[[4-(4-pyridin-4-ylphenyl)thiophene-2-carbonyl]amino]propanoicacid. Grades: 98%. CAS No. 766536-21-4. Molecular formula: C25H20N2O3S. Mole weight: 428.5.
PF-04991532
This active molecular is a hepatoselective glucokinase activator that reduces MDG (mean daily glucose), FPG (fasting plasma glucose) and glucose excursion in humans. PF-04991532 may offer glycemic control without inducing hepatic steatosis. PF-04991532 was developed by Pfizer but was discontinued in Phase-II for Type-2 diabetes mellitus in USA in 2012. Uses: Type 2 diabetes mellitus. Synonyms: PF-04991532; PF 04991532; PF04991532; PF-4991532; PF4991532; PF 4991532; UNII-AJ212MS2O2; CHEMBL2165620; AJ212MS2O2; SCHEMBL1711504; BDBM50394681; 6-[[(2S)-3-cyclopentyl-2-[4-(trifluoromethyl)imidazol-1-yl]propanoyl]amino]pyridine-3-carboxylic acid. Grades: 98%. CAS No. 1215197-37-7. Molecular formula: C18H19F3N4O3. Mole weight: 396.37.
(R)-Clodinafop
(R)-Clodinafop. Group: Biochemicals. Alternative Names: (2R) -2-[4-[ (5-Chloro-3-fluoro-2-pyridinyl) oxy]phenoxy]propanoicacid; (R) -2-[4-[ (5-chloro-3-fluoro-2-pyridinyl) oxy]phenoxy]propanoicacid; CGA 193469. Grades: Highly Purified. CAS No. 114420-56-3. Pack Sizes: 1g. Molecular Formula: C14H11ClFNO4. US Biological Life Sciences.