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Pyrimido[1,2-a]purin-10(1H)-one M1G is a secondary DNA damage product arising from primary reactive oxygen species (ROS) damage to membrane lipids or deoxyribose. Group: Biochemicals. Alternative Names: Pyrimido[1,2-a]purin-10(3H)-one. Grades: Highly Purified. CAS No. 103408-45-3. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
Pyrimido-4-5-c-pyridazin-5-(1H)--one Pyrimido-4-5-c-pyridazin-5-(1H)--one. Group: Biochemicals. Grades: Highly Purified. CAS No. 34122-01-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C6H4N4O. US Biological Life Sciences. USBiological 8
Worldwide
pyrimidodiazepine synthase In the reverse direction, the reduction of 6-pyruvoyl-tetrahydropterin is accompanied by the opening of the 6-membered pyrazine ring and the formation of the 7-membered diazepine ring. The pyrimidodiazepine formed is an acetyldihydro derivative. Involved in the formation of the eye pigment drosopterin in Drosophila melanogaster. Group: Enzymes. Synonyms: PDA synthase; pyrimidodiazepine:oxidized-glutathione oxidoreductase (ring-opening, cyclizing); pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing). Enzyme Commission Number: EC 1.5.4.1. CAS No. 93586-06-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1555; pyrimidodiazepine synthase; EC 1.5.4.1; 93586-06-2; PDA synthase; pyrimidodiazepine:oxidized-glutathione oxidoreductase (ring-opening, cyclizing); pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing). Cat No: EXWM-1555. Creative Enzymes
1-(2-Methoxyethyl)-7-phenyl-1H-pyrimido-[4,5-d][1,3]oxazine-2,4-dione 1-(2-Methoxyethyl)-7-phenyl-1H-pyrimido-[4,5-d][1,3]oxazine-2,4-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 76361-14-3, 1-(2-methoxyethyl)-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione, 1-(2-Methoxyethyl)-7-phenyl-1H-pyrimido-[4,5-d][1,3]oxazine-2,4-dione, CTK5E2851, MolPort-016-578-922, AKOS015852485, AG-L-24340, KB-213219, A9687, FT-0682622, I03-0596, 1-(2-methoxyethyl)-7-phenylpyrimido[4,5-d][1,3]oxazine-2,4-dione, 1-(2-Methoxyethyl)-7-phenyl-1H-pyrimido-[4,5-d] [1,3]oxazine-2,4-dione. Product Category: Heterocyclic Organic Compound. CAS No. 76361-14-3. Molecular formula: C15H13N3O4. Mole weight: 299.29. Purity: 0.96. IUPACName: 1-(2-methoxyethyl)-7-phenylpyrimido[4,5-d][1,3]oxazine-2,4-dione. Canonical SMILES: COCCN1C2=NC(=NC=C2C(=O)OC1=O)C3=CC=CC=C3. Density: 1.338g/cm³. Product ID: ACM76361143. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
1,3-Dimethyl-3,4,5,6-tetrahydro-2H-pyrimidone Dimethyl-3,4,5,6-tetrahydro-2H-pyrimidone. CAS No. 7226-23-5. Categories: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1h)-pyrimidinone. Richman Chemical
Pennsylvania PA
1,5,7-Triazabicyclo(4.4.0)dec-5-ene (1,3,4,6,7,8-hexahydro-2H-pyrimido(1,2-a)pyrimidine) 5g Pack Size. Group: Building Blocks, Organics, Pyrimidines. Formula: C7H13N3. CAS No. 5807-14-7. Prepack ID 18977285-5g. Molecular Weight 139.2. See USA prepack pricing. Molekula Americas
1,7-Diphenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione 1,7-Diphenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,7-Diphenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione, 76360-78-6, CTK5E2842, MolPort-016-578-916, AKOS015840711, AG-L-24332, A9677, FT-0682619, 1,7-diphenylpyrimido[4,5-d][1,3]oxazine-2,4-dione, I14-14826. Product Category: Heterocyclic Organic Compound. CAS No. 76360-78-6. Molecular formula: C18H11N3O3. Mole weight: 317.31. Purity: 0.96. IUPACName: 1,7-diphenylpyrimido[4,5-d][1,3]oxazine-2,4-dione. Canonical SMILES: C1=CC=C(C=C1)C2=NC=C3C(=N2)N(C(=O)OC3=O)C4=CC=CC=C4. Density: 1.396g/cm³. Product ID: ACM76360786. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
1H-Pyrimido[4,5-c][1,2]oxazin-7(3H)-one,6-(2-Deoxy-b-d-erythro-pentofuranosyl)-4,6-dihydro- 1H-Pyrimido[4,5-c][1,2]oxazin-7(3H)-one,6-(2-Deoxy-b-d-erythro-pentofuranosyl)-4,6-dihydro-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-(BETA-D-2-DEOXYRIBOFURANOSYL)-3,4-DIHYDRO-8H-PYRIMIDO-[4,5-C][1,2]OXAZIN-7-ONE;6-(2-Deoxy-beta-D-erythro-pentofuranosyl)-4,6-dihydro-1H-pyrimido(4,5-C)(1,2)oxazin-7(3H)-one. Product Category: Heterocyclic Organic Compound. CAS No. 126128-42-5. Molecular formula: C11H15N3O5. Mole weight: 269.2539. Purity: 0.96. IUPACName: 6-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,4-dihydro-1H-pyrimido[4,5-c]oxazin-7-one. Canonical SMILES: C1CONC2=NC(=O)N(C=C21)C3CC(C(O3)CO)O. Density: 1.8 g/cm³. Product ID: ACM126128425. Alfa Chemistry — ISO 9001:2015 Certified. Categories: SCHEMBL544600. Alfa Chemistry. 5
1-Isopropyl-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione 1-Isopropyl-7-phenyl-1H-pyrimido[4,5-d][1,3]oxazine-2,4-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-ISOPROPYL-7-PHENYL-1H-PYRIMIDO[4,5-D][1,3]OXAZINE-2,4-DIONE, CTK6A9456, AKOS015838392, DA-17578, I14-14760, 1-isopropyl-7-phenylpyrimido[4,5-d][1,3]oxazine-2,4-dione, 1-Isopropyl-7-phenyl-1H-pyrimido-[4,5-d] [1,3]oxazine-2,4-dione, 1253792-13-0. Product Category: Heterocyclic Organic Compound. CAS No. 1253792-13-0. Molecular formula: C15H13N3O3. Mole weight: 283.282020 [g/mol]. Purity: 0.96. IUPACName: 7-phenyl-1-propan-2-ylpyrimido[4,5-d][1,3]oxazine-2,4-dione. Canonical SMILES: CC(C)N1C2=NC(=NC=C2C(=O)OC1=O)C3=CC=CC=C3. Product ID: ACM1253792130. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
2, 2', 2'', 2'''- [ [4- [ (2-Hydroxyethyl) amino] -8- (1-piperidinyl) pyrimido [5, 4-d] pyrimidine-2, 6-diyl] dinitrilo] tetrakisethanol. (Dipyridamole Impurity) 2, 2', 2'', 2'''- [ [4- [ (2-Hydroxyethyl) amino] -8- (1-piperidinyl) pyrimido [5, 4-d] pyrimidine-2, 6-diyl] dinitrilo] tetrakisethanol (Dipyridamole Impurity). Group: Biochemicals. Alternative Names: Pyrimido[5,4-d]pyrimidine Ethanol Deriv. Grades: Highly Purified. CAS No. 60286-30-8. Pack Sizes: 10mg. Molecular Formula: C21H36N8O5, Molecular Weight: 480.56. US Biological Life Sciences. USBiological 3
Worldwide
2, 4, 6, 8-Tetrachloropyrimido[5, 4-d]pyrimidine Potential tyrosine kinase signal transduction inhibitor. A pyrimido[5,4-d]pyrimidine derivative used as an intermediate in the preparation of nucleoside transporter 1 inhibitors and potential modulators of the activity of antimetabolite antitumor agents. Group: Biochemicals. Alternative Names: Tetrachloropyrimido[5, 4-d]pyrimidine; NSC 96654. Grades: Highly Purified. CAS No. 32980-71-5. Pack Sizes: 500mg, 1g. Molecular Formula: C?Cl?N?, Molecular Weight: 269.9. US Biological Life Sciences. USBiological 3
Worldwide
2,6-Dichloro-4,8-(dipiperidino-d20)pyrimido[5,4-d]pyrimidine An antitumor nucleoside pyrimido pyrimidine. Group: Biochemicals. Alternative Names: 2,6-Dichloro-4,8-(di-1-piperidinyl-d10)-pyrimido[5,4-d]pyrimidine. Grades: Highly Purified. CAS No. 1189450-21-2. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
2, 6-Dichloro-4, 8-dipiperidinopyrimido [5, 4-d]pyrimidine An antitumor nucleoside pyrimido pyrimidine. Group: Biochemicals. Alternative Names: 2,6-Dichloro-4,8-di-1-piperidinyl-pyrimido[5,4-d]pyrimidine. Grades: Highly Purified. CAS No. 7139-2-8. Pack Sizes: 1g. US Biological Life Sciences. USBiological 2
Worldwide
2-Chloro-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one 2-Chloro-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one is a general reagent in pharmaceutical syntheses. Group: Biochemicals. Grades: Highly Purified. CAS No. 943995-32-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C6H4ClN3O2, Molecular Weight: 185.57. US Biological Life Sciences. USBiological 10
Worldwide
2-Isopropyl-6-methyl-4-pyrimidone 2-Isopropyl-6-methyl-4-pyrimidone, is an intermediate used for the synthesis of various benzophenone derivatives, having antifungal and antibacterial activities. It can also be used for the synthesis of Diazinon (D416880), and Diazoxon (D416890), the organophosphate insecticides. Group: Biochemicals. Grades: Highly Purified. CAS No. 2814-20-2. Pack Sizes: 500mg, 5g. Molecular Formula: C8H12N2O. US Biological Life Sciences. USBiological 10
Worldwide
2-Isopropyl-6-methyl-4-pyrimidone-d6 Isotope labelled 2-Isopropyl-6-methyl-4-pyrimidone, is an intermediate used for the synthesis of various benzophenone derivatives, having antifungal and antibacterial activities. It can also be used for the synthesis of Diazinon (D416880), and Diazoxon (D416890), the organophosphate insecticides. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C8H6D6N2O, Molecular Weight: 158.229999999999. US Biological Life Sciences. USBiological 10
Worldwide
2-Methylthio-4-pyrimidone 99+% (HPLC) 2-Methylthio-4-pyrimidone 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. USBiological 4
Worldwide
3-(2-Deoxy-β-d-erythro-pentofuranosyl)pyrimido[1,2-a]purin-10(3H)-one 3-(2-Deoxy-β-d-erythro-pentofuranosyl)pyrimido[1,2-a]purin-10(3H)-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: M1G-DR. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 87171-83-3. Molecular formula: C13H13N5O4. Mole weight: 303.27. Purity: 0.96. IUPACName: 3-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimido[1,2-a]purin-10-one. Canonical SMILES: C1C(C(OC1N2C=NC3=C2N=C4N=CC=CN4C3=O)CO)O. Density: 1.87g/cm³. Product ID: ACM87171833. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
3-(2-Deoxy- β -D-erythro-pentofuranosyl) pyrimido[1, 2-a]purin-10 (3H) -one The major labeled DNA adduct of endogenous carcinogen malondialdehyde. Group: Biochemicals. Alternative Names: M1G-DR. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
3-(2-Deoxy-β-D-erythro-pentofuranosyl)pyrimido[1,2-a]purin-10(3H)-one The major DNA adduct of endogenous carcinogen malondialdehyde. Uses: The major dna adduct of endogenous carcinogen malondialdehyde. Synonyms: M1G-DR. Grades: 99%. CAS No. 87171-83-3. Molecular formula: C13H13N5O4. Mole weight: 303.27. BOC Sciences 2
(3aR,4R,12R,12aR)-3a,4,12,12a-Tetrahydro-2,2-dimethyl-4,12-epoxy-5H,8H-1,3-dioxolo[4,5-e]pyrimido[2,1-b][1,3]oxazocin-8-one (3aR,4R,12R,12aR)-3a,4,12,12a-Tetrahydro-2,2-dimethyl-4,12-epoxy-5H,8H-1,3-dioxolo[4,5-e]pyrimido[2,1-b][1,3]oxazocin-8-one is a potential drug being studied in biomedicine to treat various types of cancer. It has been found to inhibit the enzyme MELK, which is overexpressed in certain cancer cells. Studies have shown promising results in inhibiting the growth of tumors in preclinical models and further research is being conducted to determine its safety and efficacy in humans. Synonyms: 2',3'-O-isopropylidene-5',6-anhydrouridine. CAS No. 3868-21-1. Molecular formula: C12H14N2O5. Mole weight: 266.25. BOC Sciences 3
5H-Pyrimido[4,5-b][1,5]benzodiazepin-5-one, 6,11-dihydro- 5H-Pyrimido[4,5-b][1,5]benzodiazepin-5-one, 6,11-dihydro-. CAS No: 19573-56-9 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
5-Methyl-2-pyrimidone 5-Methyl-2-pyrimidone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Hydroxy-5-methylpyrimidine;2(1H)-Pyrimidinone, 5-methyl- (7CI,9CI);5-Methyl-2-Pyrimidone;5-methyl-2-pyrimidinone;2(1H)-Pyrimidinone, 5-methyl-;5-Methyl-2(1H)-pyrimidinone. Product Category: Heterocyclic Organic Compound. CAS No. 41398-85-0. Molecular formula: C5H6N2O. Mole weight: 110.11394. Purity: 0.96. IUPACName: 5-methyl-1H-pyrimidin-2-one. Canonical SMILES: CC1=CNC(=O)N=C1. Density: 1.22g/cm³. Product ID: ACM41398850. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
6-(2-Deoxy-5-O-DMT-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido-[4,5-c][1,2]oxazin-7-one 6-(2-Deoxy-5-O-DMT-b-D-ribofuranosyl)-3,4-dihydro-8H-pyrimido-[4,5-c][1,2]oxazin-7-one is a remarkable biomedical compound, exhibiting exceptional utility in research of an array of malignancies, notably leukemia and solid tumors. Synonyms: 6-(β-D-5-O-(4,4'-Dimethoxytrityl)-2-deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one; 6-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-erythro-pentofuranosyl]-4,6-dihydro-1H-pyrimido[4,5-c][1,2]oxazin-7(3H)-one. Grades: ≥95%. CAS No. 126128-43-6. Molecular formula: C32H33N3O7. Mole weight: 571.62. BOC Sciences 2
6-(b-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one 6-(b-D-2-Deoxyribofuranosyl)-3,4-dihydro-8H-pyrimido[4,5-c][1,2]oxazin-7-one, a versatile drug boasting both antiviral and antitumor properties, has become an invaluable instrument in the medicinal world. Through its DNA synthesis interference, it displays its prowess in staving off viruses and cancerous cells alike, thereby serving as a beacon of hope for those stricken with HIV, leukemia, and solid tumors. Notable for its unique structure and mode of operation, this remarkable molecule has cemented its reputation as a priceless commodity in the realm of biomedical research. Synonyms: 6-((2S,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-1H-pyrimido[4,5-c][1,2]oxazin-7(6H)-one; 6-(2-Deoxy-beta-D-erythro-pentofuranosyl)-4,6-dihydro-1H-pyrimido(4,5-c)(1,2)oxazin-7(3H)-one. Grades: ≥95%. CAS No. 126128-42-5. Molecular formula: C11H15N3O5. Mole weight: 269.25. BOC Sciences 2
6H-?Pyrimido[4, ?5-?b]?[1, ?4]?benzodiazepin-?6-?one, 5, ?11-?dihydro-?2-?[[2-?methoxy-?4-? (4-?methyl-?1-?piperazinyl) ?phenyl]?amino]?-?5, ?11-?dimethyl- An effective inhibitior of ERK5, could probably be used as an antitumor agent. IC50: 0.19μM(EC50 for cellular),of 0.087 μM(for enzymatic) and 0.087 μM(for LRRK2). Uses: An effective inhibitior of erk5 and could probably be used as an antitumor agent. Synonyms: ERK5-IN-1; ERK5 IN 1; ERK5IN1; CHEMBL1673039; SCHEMBL618262; BDBM50337127; ZINC66066276; CS-4938; HY-14403. Grades: 98%. CAS No. 1234479-76-5. Molecular formula: C25H29N7O2. Mole weight: 459.54. BOC Sciences 10
Asperloxine A ((S)-4, 10-Dimethoxy-14, 15, 16, 16a-tetrahydro-benzo[e]oxepino[2', 3':4, 5]pyrimido[2, 1-c]pyrrolo[1, 2-a][1, 4]diazepine-6, 12-dione) Natural benzodiazepine. Anti-inflammatory. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 4
Worldwide
b-Catenin/Tcf Inhibitor II, PKF118-310 (1,6-Dimethylpyrimido[5,6-e][1,2,4]triazine-5,7-dione, Wnt Pathway Inhibitor IV) A synthetic cell-permeable actinobacteria pyrimidotriazine-dione that selectively disrupts b-catenin-Tcf4 interaction (IC50=0.8uM in cell-free binding assays) and inhibits b-catenin-regulated cellular transcription activity (IC50=0.3uM in HCT116-based reporter assays). PKF118-310 is demonstrated to reverse b-catenin, but not siamois, mRNA-induced ventral body axis formation in Xenopus embryos, while direct tumor site injection (1mg/kg/0.5 wk) in HepG2 xenograph mice is shown to increase the number of apoptotic cells and decrease the expression of b-catenin target genes (cyclin D1, c-Myc, survivin) in the tumor mass, resulting in an effective tumor growth retardation (by ~60% after a 4-wk treatment period) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
Benzyl 2,4-dichloro-8,9-dihydro-5H-pyrimido-[4,5-d]azepine-7(6H)-carboxylate Benzyl 2,4-dichloro-8,9-dihydro-5H-pyrimido-[4,5-d]azepine-7(6H)-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1207362-38-6, Benzyl 2,4-dichloro-8,9-dihydro-5H-pyrimido-[4,5-d]azepine-7(6H)-carboxylate, BENZYL 2,4-DICHLORO-8,9-DIHYDRO-5H-PYRIMIDO[4,5-D]AZEPINE-7(6H)-CARBOXYLATE, CTK4B2005, MolPort-016-578-821, AKOS015850400, AG-L-20785, PB22797, FT-0682497, I03-1211, benzyl 2,4-dichloro-5H,6H,8H,9H-pyrimido[4,5-d]azepine-7-carboxylate, BENZYL 2,4-DICHLORO-5,6,8,9-TETRAHYDRO-7H-PYRIMIDO[4,5-D]AZEPINE-7-CARBOXYLATE. Product Category: Heterocyclic Organic Compound. CAS No. 1207362-38-6. Molecular formula: C16H15Cl2N3O2. Mole weight: 352.22. Purity: 0.96. IUPACName: benzyl 2,4-dichloro-5,6,8,9-tetrahydropyrimido[4,5-d]azepine-7-carboxylate. Product ID: ACM1207362386. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
Benzyl 2,4-dioxo-3,4,5,6,8,9-hexahydro-1H-pyrimido[4,5-d]azepine-7(2H)-carboxylate Benzyl 2,4-dioxo-3,4,5,6,8,9-hexahydro-1H-pyrimido[4,5-d]azepine-7(2H)-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Benzyl 2,4-dioxo-3,4,5,6,8,9-hexahydro-1H-pyrimido[4,5-d]azepine-7(2H)-carboxylate, 1207369-43-4, SureCN1839303, CTK4B2006, MolPort-016-578-820, ANW-62046, AKOS015855779, AG-L-20786, AK102526, KB-47740, FT-0682496, I03-1401, benzyl 2,4-dioxo-1H,3H,5H,6H,8H,9H-pyrimido[4,5-d]azepine-7-carboxylate. Product Category: Heterocyclic Organic Compound. CAS No. 1207369-43-4. Molecular formula: C16H17N3O4. Mole weight: 315.33. Purity: 0.96. IUPACName: benzyl 2,4-dioxo-5,6,8,9-tetrahydro-1H-pyrimido[4,5-d]azepine-7-carboxylate. Product ID: ACM1207369434. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
cis-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid cis-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: cis-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid. Product Category: Heterocyclic Organic Compound. CAS No. 701234-65-3. Molecular formula: C22H26N4O3. Mole weight: 394.472. Purity: 0.96. IUPACName: 2-[4-[4-(4-amino-7,7-dimethylpyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexyl]acetic acid. Canonical SMILES: CC1(C(=NC2=C(N=CN=C2O1)N)C3=CC=C(C=C3)C4CCC(CC4)CC(=O)O)C. Density: 1.36. Product ID: ACM701234653. Alfa Chemistry — ISO 9001:2015 Certified. Categories: 701232-20-4. Alfa Chemistry. 5
Compound 401 (2-(4-Morpholinyl)-4H-pyrimido[2,1-a]isoquinolin-4-one) Cell-permeable. A reversible and selective inhibitor of DNA-dependent protein kinase (DNA-PK) (IC?? = 0.28uM) that also targets mTOR (IC50 = 5. 3uM), but not PI 3-K in vitro. Induces apoptosis in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 168425-64-7. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
Worldwide
Dipyridamole-d20 (2, 2’, 2’’, 2’’’-[ (4, 8-Di-1-piperidinyl-d20-pyrimido[5, 4-d]pyrimidine-2, 6-diyl) dinitrilo]tetrakis-ethanol, NSC-515776-d20, RA-8-d20, Anginal-d20, Cardoxin-d20, Cleridium-d20, Dipyridan-d20, Natyl-d20, Peridamol-d20, Persantine-d20) Selective inhibitor of phosphodiesterase V (PDE 5); potent coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation. Group: Biochemicals. Alternative Names: 2, 2’, 2’’, 2’’’-[ (4, 8-Di-1-piperidinyl-d20-pyrimido[5, 4-d]pyrimidine-2, 6-diyl) dinitrilo]tetrakis-ethanol; NSC-515776-d20; RA-8-d20; Anginal-d20; Cardoxin-d20; Cleridium-d20; Dipyridan-d20; Natyl-d20; Peridamol-d20; Persantine-d20. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Hdm2 E3 Ligase Inhibitor II, HLI373 (5- (3-Dimethylaminopropyl amino) -3, 10-dimethyl-10H-pyrimido [4, 5-b] quinoline-2, 4-dione, 2HCl, MDM2 Inhibitor VI, MDM2 E3 Ligase Inhibitor II) A cell-permeable pyrimidoquinoline-dione compound that acts as an efficient Hdm2 E3 ligase inhibitor, prevents Hdm2-mediated p53 ubiquitination and increases the cellular levels of both p53 and Hdm2 (IC50 ~3uM in RPE cells). Shown to selectively arrest the growth of several tumor cells in a p53-dependent manner and display desirable aqueous solubility. Group: Biochemicals. Grades: Highly Purified. CAS No. 502137-98-6. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 4
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Ketohexokinase Inhibitor (N8-(Cyclopropylmethyl)-N4-(2-(methylthio)phenyl)-2-(1-piperazinyl)-pyrimido[5,4-d]pyrimidine-4,8-diamine, KHK Inhibitor) An orally bioavailable pyrimidinopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of human hepatic KHK activity (KHK-C isoform; IC50=12nM in a transcreener ADP assay) and efficiently blocks fructose-1-phosphate secretion (IC50 ≤ 400nM in HepG2 cells). Displays ~50-fold lower potency towards metabolic kinases, namely, ribokinase, hexokinase and adenosine kinase, and minimal binding affinities to diverse receptors and ion-channels, and excellent selectivity among a panel of 31-kinases including Akt1, AMPK, CaMKI/II, InsR, IRAK4, PKA and PKCtheta (IC50 >> 10uM). Shown to minimally affect the activities of human cytochrome p450 isozymes (1A2, 2C19, 2D6, 2C9 and 3A4), and exhibit high volume of distribution and high rate of clearance in rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?S 2HCl. US Biological Life Sciences. USBiological 4
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(R)-8-(1-acryloylpiperidin-3-yl)-10-(4-phenoxyphenyl)-3,4-dihydropyrazolo[4,3-e]pyrimido[1,2-c]pyrimidin-2(8H)-one An impurity of Ibrutinib, a medication used to treat refractory chronic lymphocytic leukemia (CLL) and mantle cell lymphoma. Synonyms: Ibrutinib Impurity MDGH. Grades: ≥95%. CAS No. 1917333-91-5. Molecular formula: C28H26N6O3. Mole weight: 494.54. BOC Sciences 8
Trequinsin, Hydrochloride (9,10-Dimethoxy-2-mesitylimino-3-methyl-2,3,6,7-tetrahydro-4H-pyrimido-(6,1-a)-isoquinolin-4-one, HCl, HL 725) Extremely potent and cell-permeable inhibitor of cGMP-inhibited phosphodiesterase (IC50=300 pM) and platelet aggregation in vitro. Potentiates adenosine-stimulated cAMP accumulation.CAS Number:78416-81-6. Group: Biochemicals. Grades: Highly Purified. CAS No. 78416-81-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O? · HCl, Primary Target: cGMP-inhibited phosphodiesterase. US Biological Life Sciences. USBiological 4
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1,3-Dimethyluracil 1,3-Dimethyluracil is a pyrimidone derives from a uracil. 1,3-Dimethyluracil found occasionally in human urine. 1,3-Dimethyluracil shows inhibition activity against hCA I and hCA II (human carbonic anhydrase) with K i of 316.2 μM and 166.4 μM, respectively [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 874-14-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W008343. MedChemExpress MCE
1, 5, 7-Triazabicyclo[4. 4. 0]dec-5-ene 1, 5, 7-Triazabicyclo[4. 4. 0]dec-5-ene. Group: Biochemicals. Alternative Names: 1,3,4,6,7,8-Hexahydro-2H-pyrimido[1,2-a]pyrimidine. Grades: Highly Purified. CAS No. 5807-14-7. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C7H13N3. US Biological Life Sciences. USBiological 8
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15-Lipoxygenase Inhibitor 1 15-Lipoxygenases (15-LO) inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 μM. Synonyms: 15-LO Inhibitor 1; 4-methyl-2-(4-methylpiperazin-1-yl)-5H-pyrimido[4,5-b][1,4]benzothiazine. Grades: ≥95%. CAS No. 928853-86-5. Molecular formula: C16H19N5S. Mole weight: 313.4. BOC Sciences 10
1,8-Diazabicyclo[5.4.0]undec-7-ene,compound with p-toluenesulfonic acid(1:1) 1,8-Diazabicyclo[5.4.0]undec-7-ene,compound with p-toluenesulfonic acid(1:1). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,8-DIAZABICYCLO[5.4.0]UNDEC-7-ENE, COMPOUND WITH P-TOLUENESULFONIC ACID (1:1);Pyrimido[1,2-a]azepine,2,3,4,6,7,8,9,10-octahydro-,mono(4-methylbenzenesulfonate);2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepinium (p-tolylsulphonate);1,8-DIAZABICYCLO(5.4.0). Product Category: Polymer/Macromolecule. CAS No. 51376-18-2. Molecular formula: C16H24N2O3S. Mole weight: 324.44. Purity: 0.96. IUPACName: 4-methylbenzenesulfonate; 2,3,4,6,7,8,9,10-octahydro-1H-pyrimido[1,2-a]azepin-5-ium. Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.C1CCC2=NCCCN2CC1. ECNumber: 257-164-3. Product ID: ACM51376182. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
(1α, 3α, 5α)-3, 5-dihydroxy-cyclohexanecarboxylic Acid Methyl Ester (1α, 3α, 5α)-3, 5-dihydroxy-cyclohexanecarboxylic Acid Methyl Ester can be used as a starting material to synthesize pyrimido[4,5-d]pyrimidinones as selective inhibitors of both KDR and FGFR kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 156526-48-6. Pack Sizes: 500mg, 5g. Molecular Formula: C8H14O4, Molecular Weight: 174.19. US Biological Life Sciences. USBiological 9
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1-Methyl-1H-indole-3-carbonyl Chloride 1-Methyl-1H-indole-3-carbonyl Chloride has been used as a reactant in the preparation of indolo[2,3-a]pyrimido[5,4-c]carbazole derivatives as anti-cancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 126921-19-5. Pack Sizes: 50mg, 500mg. Molecular Formula: C10H8ClNO, Molecular Weight: 193.63. US Biological Life Sciences. USBiological 9
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2,3'-Anhydrothymidine 2,3'-Anhydrothymidine, a biomedical compound, emerges as a promising therapeutic agent against viral infections caused by thymidine kinase-dependent DNA viruses, including herpes simplex viruses and varicella-zoster virus. Its distinctive ability lies in its interference with viral DNA synthesis, thus showcasing potent antiviral activity. Uses: An intermediate in the preparation of thymidine derivatives. Synonyms: 2'-Deoxy-3',2-anhydro-5-methyluridine; Anhydrothymidine; O2,3'-Cyclothymidine; 2,3'-O-Cyclothymidine; NSC 144601; (2R,3R,5R)-2,3-Dihydro-3-(hydroxymethyl)-8-methyl-2,5-methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one; 2,3'-Anhydro-1-(2'-deoxy-β-D-threo-pentofuranosyl)thymine. Grades: ≥95%. CAS No. 15981-92-7. Molecular formula: C10H12N2O4. Mole weight: 224.21. BOC Sciences 2
2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt 2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity. Group: Biochemicals. Alternative Names: 4,5-Triamino-6-pyrimidinol-13C2 Sulfate Salt; 2,4,5-Triaminopyrimidin-6(1H)-one-13C2 Sulfate Salt; 2,5,6-Triamino-4(1H)-pyrimidone-13C2 Sulfate Salt; 2,5,6-Triamino-4-hydroxypyrimidine-13C2 Sulfate Salt; 2,5,6-Triamino-4-oxopyrimidine-13C2 Sulfate Salt; 2,5,6-Triamino-4-pyrimidinol-13C2 Sulfate Salt; 2,5,6-Triamino-4-pyrimidinone-13C2 Sulfate Salt; 2,5,6-Triaminopyrimidin-4(1H)-one;-13C2 Sulfate Salt; 2,5,6-Triaminopyrimidin-4(3H)-one-13C2 Sulfate Salt; 4-Hydroxy-2,5,6-triaminopyrimidine-13C2 Sulfate Salt; 6-Hydroxy-2,4,5-triaminopyrimidine-13C2 Sulfate Salt; NSC 9313-13C2 Sulfate Salt. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 3
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2,4,5-Triamino-6-hydroxypyrimidine sulfate 2,4,5-Triamino-6-hydroxypyrimidine sulfate. Group: Biochemicals. Alternative Names: 2,5,6-Triamino-4-pyrimidol sulfate. Grades: Highly Purified. CAS No. 35011-47-3,39267-74-8. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C4H7N5OH2SO4. US Biological Life Sciences. USBiological 8
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2-(4-Bromophenyl)-acetamidine 2-(4-Bromophenyl)-acetamidine is a bromo-substituted analog of 2-Phenylacetamidine; a useful synthetic intermediate used in the synthesis of non-nucleoside reverse transcriptase inhibitors. 2-Phenylacetamidine is also used to prepare naltrexone-derived pyrido- and pyrimidomorphinans. Group: Biochemicals. Grades: Highly Purified. CAS No. 59104-21-1. Pack Sizes: 1g, 10g. Molecular Formula: C8H9BrN2, Molecular Weight: 213.07. US Biological Life Sciences. USBiological 9
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2,5'-Anhydro-2'-deoxyuridine 2,5'-Anhydro-2'-deoxyuridine is a specialized biomolecular compound primarily used in the research of viral diseases. Its inhibitory effect on viral RNA or DNA polymerase makes it a vital component in medications fighting Hepatitis B and HIV. Synonyms: (6R,8S,9R)-8-Hydroxy-7,8,9,10-tetrahydro-6,9-epoxypyrimido[2,1-b][1,3]oxazocin-2(6H)-one; 2,5'-Anhydro-1-(2-deoxy-beta-D-erythro-pentofuranosyl)uracil; 6,9-Epoxy-2H,6H-pyrimido[2,1-b][1,3]oxazocin-2-one, 7,8,9,10-tetrahydro-8-hydroxy-, (6R,8S,9R)-. Grades: ≥95%. CAS No. 20701-12-6. Molecular formula: C9H10N2O4. Mole weight: 210.19. BOC Sciences 2
2-(9-Oxoxanthen-2-yl)propionic Acid 1,5,7-Triazabicyclo[4.4.0]dec-5-ene Salt 2-(9-Oxoxanthen-2-yl)propionic Acid 1,5,7-Triazabicyclo[4.4.0]dec-5-ene Salt. Group: Polymerization initiatorspolymerization reagents. CAS No. 1346753-09-0. Product ID: 3,4,6,7,8,9-hexahydro-2H-pyrimido[1,2-a]pyrimidine; 2-(9-oxoxanthen-2-yl)propanoic acid. Molecular formula: 407.5g/mol. Mole weight: C23H25N3O4. CC (C1=CC2=C (C=C1)OC3=CC=CC=C3C2=O)C (=O)O. C1CNC2=NCCCN2C1. InChI=1S/C16H12O4. C7H13N3/c1-9 (16 (18)19)10-6-7-14-12 (8-10)15 (17)11-4-2-3-5-13 (11)20-14; 1-3-8-7-9-4-2-6-10 (7)5-1/h2-9H, 1H3, (H, 18, 19); 1-6H2, (H, 8, 9). NHCZYSDZAMNWGB-UHFFFAOYSA-N. Alfa Chemistry Materials 4
2-(9-Oxoxanthen-2-yl)propionic Acid 1,5,7-Triazabicyclo[4.4.0]dec-5-ene Salt, ≥98% 2-(9-Oxoxanthen-2-yl)propionic Acid 1,5,7-Triazabicyclo[4.4.0]dec-5-ene Salt, ≥98%. Group: Polymerization initiators. CAS No. 1346753-09-0. Product ID: 3,4,6,7,8,9-hexahydro-2H-pyrimido[1,2-a]pyrimidine; 2-(9-oxoxanthen-2-yl)propanoic acid. Molecular formula: 407.5g/mol. Mole weight: C23H25N3O4. CC (C1=CC2=C (C=C1)OC3=CC=CC=C3C2=O)C (=O)O. C1CNC2=NCCCN2C1. InChI=1S/C16H12O4. C7H13N3/c1-9 (16 (18)19)10-6-7-14-12 (8-10)15 (17)11-4-2-3-5-13 (11)20-14; 1-3-8-7-9-4-2-6-10 (7)5-1/h2-9H, 1H3, (H, 18, 19); 1-6H2, (H, 8, 9). NHCZYSDZAMNWGB-UHFFFAOYSA-N. Alfa Chemistry Materials 4
2-Amino-4,5-dimethylbenzothiazole 2-Amino-4,5-dimethylbenzothiazole is a reagent used in the synthesis of a series of substituted pyrimido[2,1-b]benzothiazoles which exhibit antimicrobial activity. 2-Amino-4,5-dimethylbenzothiazole can also be used as a potential modulator of SKCa, IKCa, and BKCa channels. Group: Biochemicals. Grades: Highly Purified. CAS No. 79050-49-0. Pack Sizes: 100mg, 1g. Molecular Formula: C9H10N2S, Molecular Weight: 178.25. US Biological Life Sciences. USBiological 9
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2-Amino-4-trifluoromethylbenzoic Acid Methyl Ester 2-Amino-4-trifluoromethylbenzoic Acid Methyl Ester is an intermediate used to prepare quinazolinedione sulfonamides as competitive AMPA receptor antagonists. It is also used in the synthesis of (arylamino) pyrimidobenzazepinones and pyrimidobenzazepinethi ones as inhibitors of polo-like kinase 1 and potential antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 61500-87-6. Pack Sizes: 1g, 5g. Molecular Formula: C9H8F3NO2, Molecular Weight: 219.16. US Biological Life Sciences. USBiological 9
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(2-Chloro-4-cyanophenyl)boronic Acid (2-Chloro-4-cyanophenyl)boronic Acid is an intermediate used to prepare fused imidazole derivatives as TTK kinase inhibitors. It is also used in the synthesis of pyrimidothiophenes as HSP90 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 677743-50-9. Pack Sizes: 100mg, 500mg. Molecular Formula: C7H5BClNO2, Molecular Weight: 181.38. US Biological Life Sciences. USBiological 10
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2'-Deoxy-3',2-anhydrouridine 2'-Deoxy-3',2-anhydrouridine is a remarkable nucleoside analog, having promise in the realm of biomedical research owing to its potent antiviral and anticancer capabilities. It assumes an important role in drug development especially in combating diseases associated with dysregulation of ribonucleic acid (RNA). Synonyms: 2,5-Methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one, 2,3-dihydro-3-(hydroxymethyl)-, (2R,3R,5R)-; (1R,9R,10R)-10-(Hydroxymethyl)-8,11-dioxa-2,6-diazatricyclo[7.2.1.02,7]dodeca-3,6-dien-5-one; (2R,3R,5R)-3-(Hydroxymethyl)-2,3-dihydro-2,5-methanopyrimido[2,1-b][1,5,3]dioxazepin-9(5H)-one; 2,3'-Anhydro-1-(2-deoxy-beta-D-lyxofuranosyl)uracil. Grades: ≥95%. CAS No. 26922-44-1. Molecular formula: C9H10N2O4. Mole weight: 210.19. BOC Sciences 2
2-Methylthio Uracil A competitive inhibitor of Nitric Oxide Synthase (NOS). Group: Biochemicals. Alternative Names: 2-(Methylthio)-4(1H)-pyrimidinone; 2-(Methylthio)-4-pyrimidinol; 2-(Methylthio)-4(1H)-pyrimidinone; 2-(Methylthio)-4(3H)-pyrimidinone; 2-(Methylthio)-4-pyrimidinol; 2-(Methylthio)-4-pyrimidinone; 2-(Methylthio)-4-pyrimidone; 2-(Methylthio)pyrimidine-4(3H)-one; 2-Methylsulfanyl-3H-pyrimidin-4-one; 2- methyl sulfanylpyrimidin-4-ol; 2-Methylthio-3H-pyrimidin-4-one; 2-Methylthio-4-hydroxypyrimidine; 2-Methylthiouracil; 4-Hydroxy-2- (methylthio) pyrimidine; NSC 125339; NSC 165518. Grades: Highly Purified. CAS No. 5751-20-2. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
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2'-O-Methyl-2,5'-anhydrouridine 2'-O-Methyl-2,5'-anhydrouridine is a crucial compound extensively utilized playing a significant role in the research and development of drugs targeting RNA-based diseases, such as cancer, viral infections and genetic disorders. Synonyms: (6R,7R,8R,9R)-8-Hydroxy-7-methoxy-7,8,9,10-tetrahydro-6,9-epoxypyrimido[2,1-b][1,3]oxazocin-2(6H)-one; [6R-(6alpha,7alpha,8alpha,9alpha)]-7,8,9,10-Tetrahydro-8-hydroxy-7-methoxy-6,9-epoxy-2H,6H-pyrimido[2,1-b][1,3]oxazocin-2-one; 6,9-Epoxy-2H,6H-pyrimido[2,1-b][1,3]oxazocin-2-one,7,8,9,10-tetrahydro-8-hydroxy-7-methoxy-, [6R-(6α, 7α, 8α, 9α)]-. Grades: ≥95%. CAS No. 175471-64-4. Molecular formula: C10H12N2O5. Mole weight: 240.21. BOC Sciences 2
2-Phenylacetamidine 2-Phenylacetamidine is a useful synthetic intermediate. It is used in the synthesis of non-nucleoside reverse transcriptase inhibitors. It is also used to prepare naltrexone-derived pyrido- and pyrimidomorphinans. Group: Biochemicals. Grades: Highly Purified. CAS No. 5504-24-5. Pack Sizes: 1g, 2.5g. Molecular Formula: C8H10N2, Molecular Weight: 134.18. US Biological Life Sciences. USBiological 10
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2-Phenylacetamidine-d5 2-Phenylacetamidine-d5 is labelled 2-Phenylacetamidine which is used in the synthesis of non-nucleoside reverse transcriptase inhibitors. It is also used to prepare naltrexone-derived pyrido- and pyrimidomorphinans. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C8H5D5N2, Molecular Weight: 139.21. US Biological Life Sciences. USBiological 10
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4(3H)-Pyrimidinone 4(3H)-Pyrimidinone. Group: Biochemicals. Alternative Names: 4(1H)-Pyrimidinone; 3H-Pyrimidin-4-one; 4(3H)-Pyrimidone; 4-Hydroxypyrimidine; 4-Oxopyrimidine; 4-Pyrimidinol; 4-Pyrimidinone; 4-Pyrimidone; Deaminoisocytosine; NSC 1575; NSC 157911. Grades: Highly Purified. CAS No. 4562-27-0. Pack Sizes: 2.5g. Molecular Formula: C4H4N2O, Molecular Weight: 96.09. US Biological Life Sciences. USBiological 3
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4-Despiperidinyl-4-hydroxy dipyridamole 4-Despiperidinyl-4-hydroxy dipyridamole. Group: Biochemicals. Alternative Names: 2, 6-Bis[bis (2-hydroxyethyl) amino]-8- (1-piperidinyl) pyrimido[5, 4-d]pyrimidin-4 (3H) -one. Grades: Highly Purified. CAS No. 68006-07-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C19H31N7O5. US Biological Life Sciences. USBiological 7
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5-Bromo-4-hydroxypyrimidine 5-Bromo-4-hydroxypyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-bromo-1H-pyrimidin-4-one;5-Bromo-4-Pyrimidone;5-BROMOPYRIMIDIN-4(1H)-ONE;5-Bromo-3,4-dihydropyrimidine-4-one;5-Bromo-4(1H)-pyrimidinone;5-Bromopyrimidine-4(3H)-one;4(1H)-Pyrimidinone, 5-bromo-;4(3H)-Pyrimidinone, 5-bromo-. Product Category: Bromine Series. CAS No. 19808-30-1. Molecular formula: C4H3BrN2O. Mole weight: 174.9834. Purity: 0.96. IUPACName: 5-bromo-1H-pyrimidin-6-one. Canonical SMILES: C1=C(C(=O)NC=N1)Br. Density: 2 g/cm³. ECNumber: 243-334-4. Product ID: ACM19808301. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
5-Deazariboflavin 5-Deazariboflavin. Group: Biochemicals. Alternative Names: 1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxopyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol; 7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Pyrimido[4,5-b]quinoline-2,4(3H,10H)-dione; Pyrimido[4,5-b]quinoline, D-ribitol deriv.; NCI 0112202; NSC 112202. Grades: Highly Purified. CAS No. 19342-73-5. Pack Sizes: 10mg. Molecular Formula: C18H21N3O6, Molecular Weight: 375.38. US Biological Life Sciences. USBiological 3
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5H-Pyrido[3,2-e]thiazolo[3,2-a]pyrimidine-5-thione 5H-Pyrido[3,2-e]thiazolo[3,2-a]pyrimidine-5-thione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5H-PYRIDO[3',2':5,6]PYRIMIDO[2,1-B][1,3]THIAZOLE-5-THIONE;5H(1,3)THIAZOLO(3,2-A)PYRIDO(3,2-E)PYRIMIDINE-5-THIONE. Product Category: Heterocyclic Organic Compound. CAS No. 106531-35-5. Molecular formula: C9H5 N3 S2. Mole weight: 219.29. Purity: 0.96. IUPACName: 5H-Thiazolopyridopyrimidin-5-thione. Density: 1.62g/cm³. Product ID: ACM106531355. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
5'-O-(4,4'-Dimethoxytrityl)-2,3'-anhydrothymidine 5'-O-(4,4'-Dimethoxytrityl)-2,3'-anhydrothymidine is a compound useful in organic synthesis. Synonyms: (2R,3R,5R)-3-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3-dihydro-8-methyl-2,5-methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one. CAS No. 191474-13-2. Molecular formula: C31H30N2O6. Mole weight: 526.58. BOC Sciences 2
5'-O-Benzoyl-2,3'-anhydrothymidine An intermediate in the preparation of anti-HIV pharmaceuticals. Group: Biochemicals. Alternative Names: (2R,3R,5R)-3-[(Benzoyloxy)methyl]-2,3-dihydro-8-methyl-2,5-methano-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one; 2,3'-Anhydro-5'-O-benzoylthymidine. Grades: Highly Purified. CAS No. 70838-44-7. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
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5'-O-Benzoyl-2,3'-anhydrothymidine-d3 An intermediate in the preparation of labeled anti-HIV pharmaceuticals. Group: Biochemicals. Alternative Names: (2R,3R,5R)-3-[(Benzoyloxy)methyl]-2,3-dihydro-8-methyl-2,5-(methano-d3)-5H,9H-pyrimido[2,1-b][1,5,3]dioxazepin-9-one; 2,3'-Anhydro-5'-O-benzoylthymidine-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
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6-Des(diethanolamino)-6-chloro Dipyridamole Dipyridamole impurity. An antitumor nucleoside pyrimido pyrimidine. Group: Biochemicals. Alternative Names: 2, 2'-[(6-Chloro-4, 8-di-1-piperidinylpyrimido[5, 4-d]pyrimidin-2-yl)imino]bis-ethanol; 2-Diethanolamino-6-chloro-4, 8-dipiperidinopyrimido [5, 4-d]pyrimidine. Grades: Highly Purified. CAS No. 54093-92-4. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
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8,10-Dimethyl-2,4,5,8,10-pentazabicyclo[4.4.0]deca-1,5-diene-3,7,9-trione 8,10-Dimethyl-2,4,5,8,10-pentazabicyclo[4.4.0]deca-1,5-diene-3,7,9-trione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ST086812, pyrimido[4,5-e]-1,2,4-triazine-3,6,8(2h,5h,7h)-trione, 5,7-dimethyl-, 7271-90-1, NSC21960, AC1L5GIK, AC1Q6AP8, Oprea1_229965, CTK5D6698, MolPort-002-735-361, AR-1L2828, NSC-21960, STK686149, AKOS001893026, AG-K-80111, MCULE-7016599934, A3814/0161886, 5,7-dimethyl-2H-pyrimido[4,5-e][1,2,4]triazine-3,6,8-trione, 5,7-Dimethyl-2H,5H-pyrimido[4,5-E][1,2,4]triazine-3,6,8-trione, 5,7-dimethylpyrimido[4,5-e][1,2,4]triazine-3,6,8(2H,5H,7H)-trione, 5,7-dimethyl-5,7-dihydro-2H-pyrimidino[4,5-e]1,2,4-triazine-3,6,8-trione. Product Category: Heterocyclic Organic Compound. CAS No. 7271-90-1. Molecular formula: C7H7N5O3. Mole weight: 209.1622. Purity: 0.96. IUPACName: 5,7-dimethyl-2H-pyrimido[4,5-e][1,2,4]triazine-3,6,8-trione. Canonical SMILES: CN1C2=NC(=O)NN=C2C(=O)N(C1=O)C. Density: 1.83g/cm³. Product ID: ACM7271901. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
Alisertib MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Synonyms: MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-. Grades: 0.98. CAS No. 1028486-01-2. Molecular formula: C27H20ClFN4O4. Mole weight: 518.9. BOC Sciences
BIBU 1361 dihydrochloride BIBU 1361 dihydrochloride is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM) with ~ 100-fold lower potency than ErbB2 (IC50 = 290 nM) and selectivity over a range of other related tyrosine kinases (IC50 > 10 μM). BIBU 1361 blocks downstream EGFR signaling events such as MAPKK/MAPK activation. Synonyms: BIBU 1361 dihydrochloride; BIBU1361 dihydrochloride; BIBU-1361 dihydrochloride; N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-pyrimido[5,4-d]pyrimidin-4-amine dihydrochloride. Grades: ≥97% by HPLC. CAS No. 793726-84-8. Molecular formula: C22H27ClFN7.2HCl. Mole weight: 516.87. BOC Sciences 10

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