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| Product | Description | |
|---|---|---|
| Quinuclidine | Heterocyclic Organic Compound. Alternative Names: 1-Azabicyclo[2.2.2]octane. CAS No. 100-76-5. Molecular formula: C7H13N. Mole weight: 111.18. IUPACName: 1-azabicyclo[2.2.2]octane. Canonical SMILES: C1CN2CCC1CC2. ECNumber: 202-887-1. Catalog: ACM100765. |  |
| Quinuclidine | Quinuclidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 100-76-5. Pack Sizes: 200mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. |  Worldwide |
| Quinuclidine | Quinuclidine. Group: Organic light-emitting diode (oled) materials. Alternative Names: 1-Azabicyclo[2.2.2]octane. CAS No. 100-76-5. Product ID: 1-azabicyclo[2.2.2]octane. Molecular formula: 111.18. Mole weight: C7H13N. C1CN2CCC1CC2. InChI=1S/C7H13N/c1-4-8-5-2-7 (1)3-6-8/h7H, 1-6H2. SBYHFKPVCBCYGV-UHFFFAOYSA-N. |  |
| Quinuclidine HCl | Quinuclidine HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 39896-06-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C7H13N·HCl. US Biological Life Sciences. | Worldwide |
| 2- (Hydroxymethyl) -2- (methoxymethyl) quinuclidin-3-one | 2- (Hydroxymethyl) -2- (methoxymethyl) quinuclidin-3-one is a small molecule that has shown promising preclinical activity in various cancer types. 2- (Hydroxymethyl) -2- (methoxymethyl) quinuclidin-3-one shows antitumor activity in multiple myeloma by induction of p73 and Noxa. Group: Biochemicals. Grades: Highly Purified. CAS No. 5291-32-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C10H17NO3. US Biological Life Sciences. | Worldwide |
| 2-(Quinuclidinium)ethyl Methanethiosulfonate, Bromide | 2-(Quinuclidinium)ethyl Methanethiosulfonate, Bromide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline | 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: 2-[(3S)-1-Azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline; 1H-Benz[de]isoquinoline, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-; Palonosetron Impurity 15. Grades: ≥95%. CAS No. 1796933-62-4. Molecular formula: C19H26N2. Mole weight: 282.42. |  |
| 3-Chloro-N-(3-quinuclidinyl)benzamide | Heterocyclic Organic Compound. Alternative Names: SBB003070, 120570-07-2, 3-Chloro-N-(3-quinuclidinyl)benzamide, Benzamide,N-1-azabicyclo[2.2.2]oct-3-yl-3-chloro-, (3-chlorophenyl)-N-quinuclidin-3-ylcarboxamide, Maybridge4_000366, AC1MCXSA, ACMC-20mp07, SureCN7278577, ACMC-1BX89, Oprea1_696498, Benzamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-3-chloro-, MLS001181554, 419192_ALDRICH, CTK4B1926, MolPort-002-893-982, HMS1522A14, HMS2861E13, 120570-08-3, CCG-48000. CAS No. 120570-07-2. Molecular formula: C14H17ClN2O. Mole weight: 264.75. Purity: 0.96. IUPACName: N-(1-azabicyclo[2.2.2]octan-3-yl)-3-chlorobenzamide. Canonical SMILES: C1CN2CCC1C(C2)NC(=O)C3=CC(=CC=C3)Cl. Density: 1.27g/cm³. Catalog: ACM120570072. | |
| 3-Quinuclidinol | 3-Quinuclidinol. CAS No: 1619-34-7 |  Sarchem Laboratories New Jersey NJ |
| 3-Quinuclidinol | Hypotensive. Synthon for preparation of cholinergic receptor ligands and anesthetics. Group: Biochemicals. Alternative Names: 1-Azabicyclo[2.2.2.]-octan-3-ol; 3-Hydroxyquinuclidine; (+/-)-1-Azabicyclo[2.2.2]octan-3-ol; (+/-)-3-Quinuclidinol; NSC 93905; dl-3-Quinuclidinol. Grades: Highly Purified. CAS No. 1619-34-7. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3-Quinuclidinone HCl | 3-Quinuclidinone HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 1193-65-3. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C7H12CINO. US Biological Life Sciences. | Worldwide |
| 3-Quinuclidinone hydrochloride | Organic Phosphine Compounds. Alternative Names: 1-Azabicyclo[2.2.2]octan-3-one hydrochloride; 3-Quinuclidinone hydrochloride; 1-azabicyclo[2.2.2]octan-3-one,hydrochloride; 3-Quinuclidone hydrochloride; 3-Quinuclidnone hydrochloride; Quinuclidin-3-one hydrochloride. CAS No. 1193-65-3. Molecular formula: C7H12ClNO. Mole weight: 161.6309. Appearance: White or yelloish Powder. Purity: 0.98. IUPACName: 1-azabicyclo[2.2.2]octan-3-one;hydrochloride. Canonical SMILES: C1CN2CCC1C(=O)C2.Cl. ECNumber: 214-776-5. Catalog: ACM1193653. | |
| (3S)-Aminoquinuclidine Dihydrochloride | (3S)-Aminoquinuclidine Dihydrochloride is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: (S)-quinuclidin-3-amine dihydrochloride; (3S)-1-Azabicyclo[2.2.2]octan-3-amine Hydrochloride (1:2); (3S)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride; (3S)-quinuclidin-3-amine Dihydrochloride; 1-Azabicyclo[2.2.2]octan-3-amine, (3S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 119904-90-4. Molecular formula: C7H16Cl2N2. Mole weight: 199.12. | |
| Cevimeline, Hydrochloride Salt ((+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3-quinuclidine) | A muscarinic agonist. Group: Biochemicals. Alternative Names: (+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3-quinuclidine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| HEPTANOIC ACID, 2-HYDROXY-2-ISOPROPENTYL-, 3-QUINUCLIDINYL ESTER | HEPTANOIC ACID, 2-HYDROXY-2-ISOPROPENTYL-, 3-QUINUCLIDINYL ESTER. CAS No. 101913-73-9. Catalog: ACM101913739. | |
| N- (2-Bromoethyl) quinuclidinium, Bromide | N- (2-Bromoethyl) quinuclidinium, Bromide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-(2-BROMOETHYL)QUINUCLIDINIUM, BROMIDE | Heterocyclic Organic Compound. Alternative Names: N-(2-BROMOETHYL)QUINUCLIDINIUM, BROMIDE. CAS No. 104304-10-1. Molecular formula: C9H17Br2N. Mole weight: 299.05. Appearance: Colourless Solid. Purity: 0.96. IUPACName: 1-(2-bromoethyl)-1-azoniabicyclo[2.2.2]octane; bromide. Canonical SMILES: C1C[N+]2(CCC1CC2)CCBr.[Br-]. Catalog: ACM104304101. | |
| N-Benzoyl-N-[2-(phenyl)ethyl]-N-carbamic Acid R-Quinuclidinol Ester Succinic Acid Salt | N-Benzoyl-N-[2-(phenyl)ethyl]-N-carbamic Acid R-Quinuclidinol Ester Succinic Acid Salt. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C27H32N2O7, Molecular Weight: 496.55. US Biological Life Sciences. | Worldwide |
| (R)-(-)-3-Quinuclidinol | A impurity of Solifenacin. Solifenacin is a muscarinic M3 receptor antagoinst for treating contraction of overactive bladder with associated problems such as increased urination frequency and urge incontinence. Synonyms: (3R)-1-azabicyclo[2.2.2]octan-3-ol; (3R)-1-azabicyclo[2.2.2]octan-3-ol. Grades: 96 %. CAS No. 25333-42-0. Molecular formula: C7H13NO. Mole weight: 127.18. | |
| (R)-(-)-3-Quinuclidinol | Hypotensive. Synthon for preparation of cholinergic receptor ligands and anesthetics. Group: Biochemicals. Alternative Names: (3R)-1-Azabicyclo[2.2.2]octan-3-ol; R-(-)-Azabicyclo[2. 2. 2]octane-3-ol; (R)-3-Quinuclidol; (R)-3-Hydroxyquinuclidine; (3R)-Quinuclidin-3-ol. Grades: Highly Purified. CAS No. 25333-42-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| R-(-)-3-Quinuclidinol | R-(-)-3-Quinuclidinol. Group: Biochemicals. Alternative Names: (R)-(-)-3-Hydroxyquinuclidine; (R)-(-)-1-Azabicyclo[2.2.2]octan-3-ol. Grades: Highly Purified. CAS No. 25333-42-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C7H13NO. US Biological Life Sciences. | Worldwide |
| rac 3-Hydroxy-3-mercapto methyl quinuclidine | Intermediate in the preparation of Cevimeline and respective derivatives. Group: Biochemicals. Alternative Names: 3-(Mercaptomethyl)-1-azabicyclo[2.2.2]octan-3-ol. Grades: Highly Purified. CAS No. 107220-26-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| (S)-(-)-3-Aminoquinuclidine dihydrochloride | Organic Phosphine Compounds. Alternative Names: (S)-(-)-3-Aminoquinuclidine Dihydrochloride; (S)-(-)-3-Aminoquinuclidine dihydrochloride; (S)-(-)-3-Amino-1-azabicyclo[2.2.2]octane Dihydrochloride; (3S)-1-azabicyclo[2.2.2]octan-3-amine,dihydrochloride; (S)-3-Aminoquinuclidine dihydrochloride; (S)-Quinuclidin-3-amine dihydrochloride. CAS No. 119904-90-4. Molecular formula: C7H16Cl2N2. Mole weight: 199.12. Purity: 0.98. IUPACName: (3S)-1-azabicyclo[2.2.2]octan-3-amine;dihydrochloride. Canonical SMILES: C1CN2CCC1C(C2)N.Cl.Cl. Density: 1.24g/cm³. ECNumber: 601-641-4. Catalog: ACM119904904. | |
| S-(+)-3-Quinuclidinol | S-(+)-3-Quinuclidinol. Group: Biochemicals. Alternative Names: (S)-(+)-3-Quinuclidinol. Grades: Highly Purified. CAS No. 34583-34-1. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C7H13NO. US Biological Life Sciences. | Worldwide |
| Solifenacin-d5 Hydrochloride. ((1S)-3,4-Dihydro-1-phenyl-d5-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo-[2.2.2]oct-3-yl ester succinate, (1S, 3R) -3quinuclidinyl -1-phenyl -d5-1, 2, 3, 4-tetra hydro-2-isoquinolinecarboxyl ate succinate) | Muscarinic M3 receptor antagoinst. Group: Biochemicals. Alternative Names: (1S)-3,4-Dihydro-1-phenyl-d5-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo-[2.2.2]oct-3-yl ester succinate; (1S, 3R) -3quinuclidinyl -1-phenyl -d5-1, 2, 3, 4-tetra hydro-2-isoquinolinecarboxyl ate succinate. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Solifenacin Succinate. ((1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo-[2.2.2]oct-3-yl ester succinate, (1S, 3R) -3quinuclidinyl -1-phenyl -1, 2, 3, 4-tetra hydro-2-isoquinolinecarboxyl ate succinate) | Muscarinic M3 receptor antagoinst. In treatment of urinary incontinence. Group: Biochemicals. Alternative Names: (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic acid (3R)-1-azabicyclo-[2.2.2]oct-3-yl ester succinate; (1S, 3R) -3quinuclidinyl -1-phenyl -1, 2, 3, 4-tetra hydro-2-isoquinolinecarboxyl ate succinate. Grades: Highly Purified. CAS No. 180468-39-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (S)-quinuclidin-3-amine | (S)-Quinuclidin-3-amine is an intermediate in the synthesis of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3S)-Aminoquinuclidine; (S)-1-Azabicyclo[2.2.2]oct-3-ylamine; (S)-3-Amino-1-azabicyclo[2.2.2]octane; (S)-3-Aminoquinuclidine; (S)-(-)-3-Aminoquinuclidine; (S)-1-Azabicyclo[2.2.2]octan-3-amine. Grades: 95%. CAS No. 120570-05-0. Molecular formula: C7H14N2. Mole weight: 126.20. | |
| (S)-Quinuclidin-3-amine dihydrochloride | (S)-Quinuclidin-3-amine dihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-3-Aminoquinuclidine dihydrochloride. CAS No. 119904-90-4. Pack Sizes: 1 g; 5 g. Product ID: HY-I0034. |  |
| 1-Azabicyclo[2.2.2]octan-8-yl2-(3,4-dimethoxyphenyl)-2-hydroxy-3-methylbut-3-enoate | Heterocyclic Organic Compound. Alternative Names: CID58802, LS-89122, 3-Quinuclidyl 3, 4-dimethoxyphenyl (isopropenyl)glycolate, Mandelic acid, 3,4-dimethoxy-alpha-isopropenyl-, 3-quinuclidinyl ester, MANDELIC ACID, alpha-ISOPROPENYL-3,4-DIMETHOXY-, 3-QUINUCLIDINYL ESTER, 101710-95-6. CAS No. 101710-95-6. Molecular formula: C20H27NO5. Mole weight: 361.432 g/mol. Purity: 0.96. IUPACName: 1-azabicyclo[2.2.2]octan-3-yl 2-(3,4-dimethoxyphenyl)-2-hydroxy-3-methylbut-3-enoate. Canonical SMILES: CC (=C)C (C1=CC (=C (C=C1)OC)OC) (C (=O)OC2CN3CCC2CC3)O. Density: 1.21g/cm³. Catalog: ACM101710956. | |
| 1-Azabicyclo[2.2.2]octan-8-yl2-(4-oxo-2-phenyl-3-oxaspiro[4.4]nonan-2-yl)acetate | Heterocyclic Organic Compound. Alternative Names: 1-Oxo-3-phenyl-2-oxaspiro(4,4)nonane-3-acetic acid 3-quinuclidinyl ester, 2-OXASPIRO(4.4)NONANE-3-ACETIC ACID, 1-OXO-3-PHENYL-, 3-QUINUCLIDINYL ESTER, 101834-44-0, AC1Q6MGZ, AC1L1QD4, LS-99613, 1-azabicyclo[2.2.2]oct-3-yl (1-oxo-3-phenyl-2-oxaspiro[4.4]non-3-yl)acetate, 1-azabicyclo[2.2.2]oct-3-yl(1-oxo-3-phenyl-2-oxaspiro[4.4]non-3-yl)acetate, 1-azabicyclo[2.2.2]octan-3-yl 2-(9-oxo-7-phenyl-8-oxaspiro[4.4]nonan-7-yl)acetate. CAS No. 101834-44-0. Molecular formula: C23H29NO4. Mole weight: 383.481 g/mol. Purity: 0.96. IUPACName: 1-azabicyclo[2.2.2]octan-3-yl 2-(1-oxo-3-phenyl-2-oxaspiro[4.4]nonan-3-yl)acetate. Canonical SMILES: C1CCC2 (C1)CC (OC2=O) (CC (=O)OC3CN4CCC3CC4)C5=CC=CC=C5. Density: 1.24g/cm³. Catalog: ACM101834440. | |
| 1-Azabicyclo[2.2.2]octan-8-yl 2-cyclobutyl-2-hydroxypent-3-ynoate | Heterocyclic Organic Compound. Alternative Names: 3-Quinuclidyl cyclobutyl(1-propynyl)glycolate A, 3-Pentynoic acid, 2-cyclobutyl-2-hydroxy-, 3-quinuclidinyl ester, CYCLOBUTANEGLYCOLIC ACID, alpha-(1-PROPYNYL)-, 3-QUINUCLIDINYL ESTER, AC1L1OEE, AC1Q621O, LS-55899, 1-azabicyclo[2.2.2]oct-3-yl 2-cyclobutyl-2-hydroxypent-3-ynoate, 1-azabicyclo[2.2.2]octan-3-yl 2-cyclobutyl-2-hydroxypent-3-ynoate, 101030-75-5. CAS No. 101030-75-5. Molecular formula: C16H23NO3. Mole weight: 277.359 g/mol. Purity: 0.96. IUPACName: 1-azabicyclo[2.2.2]octan-3-yl 2-cyclobutyl-2-hydroxypent-3-ynoate. Canonical SMILES: CC#CC(C1CCC1)(C(=O)OC2CN3CCC2CC3)O. Density: 1.21g/cm³. Catalog: ACM101030755. | |
| 1-Azabicyclo[2.2.2]octan-8-yl 2-hydroxy-5-methyl-2-phenylhept-3-ynoate | Heterocyclic Organic Compound. Alternative Names: CID58820, LS-89153, 3-Quinuclidyl phenyl(3-methyl-1-pentynyl)glycolate A, 3-Quinuclidyl phenyl(3-methyl-1-pentynyl)glycolate B, Mandelic acid, alpha-(3-methyl-1-pentynyl)-, 3-quinuclidinyl ester, MANDELIC ACID, alpha-(3-METHYL-1-PENTYNYL)-, 3-QUINUCLIDINYL ESTER, 101711-10-8. CAS No. 101711-10-8. Molecular formula: C21H27NO3. Mole weight: 341.444 g/mol. Purity: 0.96. IUPACName: 1-azabicyclo[2.2.2]octan-3-yl 2-hydroxy-5-methyl-2-phenylhept-3-ynoate. Canonical SMILES: CCC (C)C#CC (C1=CC=CC=C1) (C (=O)OC2CN3CCC2CC3)O. Density: 1.17g/cm³. Catalog: ACM101711108. | |
| 1-Azabicyclo[2.2.2]octan-8-yl2-tert-butyl-2-hydroxy-5-methylhex-5-en-3-ynoate | Heterocyclic Organic Compound. Alternative Names: 3-Quinuclidyl tert-butyl(3-methyl-but-1-yn-3-enyl)glycolate A, 3-Quinuclidyl-tert-butyl(3-methyl-but-1-yn-3-enyl)glycolate B, HEXA-3-YN-5-ENOIC ACID, 2-tert-BUTYL-2-HYDROXY-5-METHYL-, 3-QUINUCLIDINYL ESTER, AC1L1P66, AC1Q621H, LS-75534, 1-azabicyclo[2.2.2]oct-3-yl 2-tert-butyl-2-hydroxy-5-methylhex-5-en-3-ynoate, 1-azabicyclo[2.2.2]octan-3-yl 2-tert-butyl-2-hydroxy-5-methylhex-5-en-3-ynoate, 101564-57-2. CAS No. 101564-57-2. Molecular formula: C18H27NO3. Mole weight: 305.412 g/mol. Purity: 0.96. IUPACName: 1-azabicyclo[2.2.2]octan-3-yl 2-tert-butyl-2-hydroxy-5-methylhex-5-en-3-ynoate. Canonical SMILES: CC (=C)C#CC (C (=O)OC1CN2CCC1CC2) (C (C) (C)C)O. Density: 1.11g/cm³. Catalog: ACM101564572. | |
| 1-Azoniabicyclo[2.2.2]octan-7-ylmethyl2-hydroxy-3-methyl-2-phenylbutanoate chloride | Heterocyclic Organic Compound. Alternative Names: 2-Quinuclidinemethylene-alpha-isopropyl-alpha-phenylglycolate hydrochloride, 2-{[(2-hydroxy-3-methyl-2-phenylbutanoyl)oxy]methyl}-1-azoniabicyclo[2.2.2]octane chloride, MANDELIC ACID, alpha-ISOPROPYL-, 2-QUINUCLIDINYLMETHYL ESTER, HYDROCHLORIDE, 101711-03-9, AC1L1PTP, AC1Q1SL3, LS-89142, 1-azoniabicyclo[2.2.2]octan-2-ylmethyl 2-hydroxy-3-methyl-2-phenylbutanoate chloride. CAS No. 101711-03-9. Molecular formula: C19H28ClNO3. Mole weight: 353.884 g/mol. Purity: 0.96. IUPACName: 1-azoniabicyclo[2.2.2]octan-2-ylmethyl 2-hydroxy-3-methyl-2-phenylbutanoate;chloride. Canonical SMILES: CC (C)C (C1=CC=CC=C1) (C (=O)OCC2CC3CC[NH+]2CC3)O. [Cl-]. Catalog: ACM101711039. | |
| 1-Boc-3-methylenepiperidine | 1-Boc-3-methylenepiperidine is a reagent used in the preparation of analogs of spirocyclic quinuclidinyl-Δ2-isoxazolines as potent and selective α7 nicotinic agonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 276872-89-0. Pack Sizes: 250mg, 1g. Molecular Formula: C11H19NO2, Molecular Weight: 197.27. US Biological Life Sciences. | Worldwide |
| (1S)-N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide | (1S)-N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-N-((R)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide; 1-Naphthalenecarboxamide, N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-1,2,3,4-tetrahydro-, (1S)-. Molecular formula: C18H24N2O. Mole weight: 284.40. | |
| (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide | (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxamide; (S)-N-((S)-quinuclidin-3-yl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide; 1-Naphthalenecarboxamide, N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-1,2,3,4-tetrahydro-, (1S)-; Palonosetron Impurity 4. Grades: ≥95%. CAS No. 177793-79-2. Molecular formula: C18H24N2O. Mole weight: 284.40. | |
| 2-(1,3-Benzodioxol-5-ylmethylidene)-1-azabicyclo[2.2.2]octan-3-one | Heterocyclic Organic Compound. Alternative Names: BRN 5754431, 2-(3,4-Methylenedioxyphenylmethylene)-3-oxoquinuclidine, 2-(1,3-Benzodioxol-5-ylmethylene)-1-azabicyclo(2.2.2)octan-3-one, 1-AZABICYCLO(2.2.2)OCTAN-3-ONE, 2-(1,3-BENZODIOXOL-5-YLMETHYLENE)-, AC1L1TEH, Maybridge1_003469, MCULE-9462413832, LS-22629, 2-(1,3-benzodioxol-5-ylmethylidene)quinuclidin-3-one, 2-[(Z)-1,3-benzodioxol-5-ylmethylidene]-3-quinuclidinone, 2-(1,3-benzodioxol-5-ylmethylidene)-1-azabicyclo[2.2.2]octan-3-one, 111896-94-7. CAS No. 111896-94-7. Molecular formula: C15H15NO3. Mole weight: 257.284 g/mol. Purity: 0.96. IUPACName: 2-(1,3-benzodioxol-5-ylmethylidene)-1-azabicyclo[2.2.2]octan-3-one. Canonical SMILES: C1CN2CCC1C(=O)C2=CC3=CC4=C(C=C3)OCO4. Density: 1.35g/cm³. Catalog: ACM111896947. | |
| 2- (2-Aminoethyl) benzonitrile Hydrochloride | 2- (2-Aminoethyl) benzonitrile Hydrochloride is an intermediate in the synthesis of (1S,3R,4S)-quinuclidin-3-yl 2-benzoylphene thylcarbamate (Q795815), which is an impurity in the synthesis of Solifenacin (S676700), muscarinic M3 receptor antagoinst. (1S,3R,4S)-quinuclidin-3-yl 2-benzoylphene thylcarbamate is used in treatment of urinary incontinence. Group: Biochemicals. Grades: Highly Purified. CAS No. 1159826-34-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H11ClN2. US Biological Life Sciences. | Worldwide |
| 2-Bromodibenzo[b, d]thiophene | 2-Bromodibenzo[b, d]thiophene acts as a reagent in the synthesis and biological evaluation of quinuclidines as squalene synthase inhibitors, properties and device performance of electron transport materials. Group: Biochemicals. Grades: Highly Purified. CAS No. 22439-61-8. Pack Sizes: 5g, 10g. Molecular Formula: C12H7BrS. US Biological Life Sciences. | Worldwide |
| (3S)-1-Azabicyclo[2.2.2]octan-3-ol | (3S)-1-Azabicyclo[2.2.2]octan-3-ol. Group: Biochemicals. Alternative Names: 1-Azabicyclo[2.2.2]octan-3-ol, (S)-; (+)-Quinuclidin-3-ol; (3S)-(+)-Quinuclidin-3-ol; (3S)-Quinuclidin-3-ol; (S)-(+)-1-Azabicyclo[2.2.2]octan-3-ol; (S)-(+)-3-Quinuclidinol; (S)-(+)-Azabicyclo[2. 2. 2]octane-3-ol; (S)-1-Azabicyclo[2.2.2]octan-3-ol; (S)-3-Hydroxyquinuclidine; (S)-3-Quinuclidinol. Grades: Highly Purified. CAS No. 34583-34-1. Pack Sizes: 25mg. Molecular Formula: C7H13NO, Molecular Weight: 127.18. US Biological Life Sciences. | Worldwide |
| (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine | (3S)-N-[[(1S)-1,2,3,4-Tetrahydro-1-naphthalenyl]methyl]-1-azabicyclo[2.2.2]octan-3-amine is an intermediate of Palonosetron. Palonosetron (INN, trade name Aloxi) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Uses: Palonosetron intermediate. Synonyms: [S-(R*,R*)]-N-[(1,2,3,4-Tetrahydro-1-naphthalenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine; (S)-N-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)quinuclidin-3-amine; Palonosetron Impurity 5. Grades: ≥95%. CAS No. 177793-80-5. Molecular formula: C18H26N2. Mole weight: 270.41. | |
| 6-Hydroxy-(S,S)-Palonosetron | 6-Hydroxy-(S,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3aR)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one; (3aR)-6-hydroxy-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR)-. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| 6-Oxo-(S,S)-Palonosetron | 6-Oxo-(S,S)-Palonosetron is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: 6-Oxo-(S,S)-Palonosetron (~90%); (S)-2-((S)-Quinuclidin-3-yl)-3,3a,4,5-tetrahydro-1H-benzo[de]isoquinoline-1,6(2H)-dione. Grades: 90%. CAS No. 848074-10-2. Molecular formula: C19H22N2O2. Mole weight: 310.39. | |
| (6S)-Hydroxy (R,S)-Palonosetron | (6S)-Hydroxy (R,S)-Palonosetron is a metabolite of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (3aR,6S)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-benz[de]isoquinolin-1-one; (3aR,6S)-6-hydroxy-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one; 1H-Benz[de]isoquinolin-1-one, 2-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3a,4,5,6-hexahydro-6-hydroxy-, (3aR,6S)-. Molecular formula: C19H24N2O2. Mole weight: 312.41. | |
| (7-Methyl-1-azabicyclo[2.2.2]octan-8-yl)2-cyclopenten-1-yl-2-hydroxy-2-phenylacetate | Heterocyclic Organic Compound. Alternative Names: 2-Methyl-3-quinuclidinyl phenyl(1-cyclopentenyl)glycolate, MANDELIC ACID, alpha-(1-CYCLOPENTENYL)-, 2-METHYL-3-QUINUCLIDINYL ESTER, AC1L1PZD, AC1Q60M9, LS-89073, (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-(cyclopenten-1-yl)-2-hydroxy-2-phenylacetate, 2-methyl-1-azabicyclo[2.2.2]oct-3-yl cyclopent-1-en-1-yl(hydroxy)phenylacetate, 101756-59-6. CAS No. 101756-59-6. Molecular formula: C21H27NO3. Mole weight: 341.444 g/mol. Purity: 0.96. IUPACName: (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-(cyclopenten-1-yl)-2-hydroxy-2-phenylacetate. Canonical SMILES: CC1C (C2CCN1CC2)OC (=O)C (C3=CCCC3) (C4=CC=CC=C4)O. Density: 1.21g/cm³. Catalog: ACM101756596. | |
| (7-Methyl-1-azabicyclo[2.2.2]octan-8-yl)2-cyclopropyl-2-hydroxy-2-phenylacetate | Heterocyclic Organic Compound. Alternative Names: CID58798, LS-89107, cis-2-Methyl-3-quinuclidyl phenyl(cyclopropyl)glycolate (mixed isomers), Mandelic acid, alpha-cyclopropyl-, 2-methyl-3-quinuclidinyl ester, (mixed isomer), MANDELIC ACID, alpha-CYCLOPROPYL-, 2-METHYL-3-QUINUCLIDINYL ESTER, (mixed isomer, 101710-92-3. CAS No. 101710-92-3. Molecular formula: C19H25NO3. Mole weight: 315.407 g/mol. Purity: 0.96. IUPACName: (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-cyclopropyl-2-hydroxy-2-phenylacetate. Density: 1.22g/cm³. Catalog: ACM101710923. | |
| (7-Methyl-1-azabicyclo[2.2.2]octan-8-yl)2-hydroxy-2-prop-1-en-2-ylheptanoate | Heterocyclic Organic Compound. Alternative Names: 2-Methyl-3-quinuclidyl-n-amyl(isopropenyl)glycolate B, 2-Methyl-3-quinuclidyl-n-amyl(isopropenyl)glycolate A, HEPTANOIC ACID, 2-HYDROXY-2-ISOPROPENTYL-, 2-METHYL-3-QUINUCLIDINYL ESTER, AC1L1QFE, AC1Q60M6, LS-74397, (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2-prop-1-en-2-ylheptanoate, 2-methyl-1-azabicyclo[2.2.2]oct-3-yl 2-hydroxy-2-(prop-1-en-2-yl)heptanoate, 101913-72-8. CAS No. 101913-72-8. Molecular formula: C18H31NO3. Mole weight: 309.444 g/mol. Purity: 0.96. IUPACName: (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2-prop-1-en-2-ylheptanoate. Canonical SMILES: CCCCCC (C (=C)C) (C (=O)OC1C (N2CCC1CC2)C)O. Density: 1.06g/cm³. Catalog: ACM101913728. | |
| (7-Methyl-1-azabicyclo[2.2.2]octan-8-yl)2-hydroxy-2-prop-1-ynylheptanoate | Heterocyclic Organic Compound. Alternative Names: CID59087, LS-74403, 2-Methyl-3-quinuclidyl-n-amyl(1-propynyl)glycolate, HEPTANOIC ACID, 2-HYDROXY-2-(1-PROPYNYL)-, 2-METHYL-3-QUINUCLIDINYL ESTER, 101913-75-1. CAS No. 101913-75-1. Molecular formula: C18H29NO3. Mole weight: 307.428 g/mol. Purity: 0.96. IUPACName: (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2-prop-1-ynylheptanoate. Canonical SMILES: CCCCCC(C#CC)(C(=O)OC1C(N2CCC1CC2)C)O. Density: 1.09g/cm³. Catalog: ACM101913751. | |
| (7-Methyl-1-azabicyclo[2.2.2]octan-8-yl)2-hydroxy-3-methyl-2-phenylbutanoate | Heterocyclic Organic Compound. Alternative Names: 2-Methyl-3-quinuclidyl phenyl(isopropyl)glycolate B, 101711-00-6, 2-Methyl-3-quinuclidyl isopropyl(phenyl)glycolate A, 2-Methyl-3-quinuclidyl phenyl(isopropyl)glycolate-M (mixed isomers), MANDELIC ACID, alpha-ISOPROPYL-, 2-METHYL-3-QUINUCLIDINYL ESTER, Benzeneacetic acid, a-hydroxy-a-(1-methylethyl)-,2-methyl-1-azabicyclo[2.2.2]oct-3-yl ester, ACMC-20m4qk, AC1L1PTD, AC1Q60M8, CTK4A0137, AG-D-09050, LS-89136, 2-methyl-1-azabicyclo[2.2.2]oct-3-yl 2-hydroxy-3-methyl-2-phenylbutanoate, (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-3-methyl-2-phenylbutanoate, (7-METHYL-1-AZABICYCLO[2.2.2]OCT-8-YL) 2-HYDROXY-3-METHYL-2-PHENYL-BUTANOATE. CAS No. 101711-00-6. Molecular formula: C19H27NO3. Mole weight: 317.423 g/mol. Purity: 0.96. IUPACName: (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-3-methyl-2-phenylbutanoate. Canonical SMILES: CC1C (C2CCN1CC2)OC (=O)C (C3=CC=CC=C3) (C (C)C)O. Density: 1.15g/cm³. Catalog: ACM101711006. | |
| (7-Methyl-1-azabicyclo[2.2.2]octan-8-yl)2-hydroxy-5-methyl-2-propan-2-ylhex-5-en-3-ynoate | Heterocyclic Organic Compound. Alternative Names: 2-Methyl-3-quinuclidyl isopropyl(3-methyl-but-1-yn-3-enyl)glycolate, Hexa-3-yn-5-enoic acid, 2-hydroxy-2-isopropyl-5-methyl-, 2-methyl-3-quinuclidinyl ester, AC1Q60LY, AC1L1P69, LS-75535, 2-methyl-1-azabicyclo[2.2.2]oct-3-yl 2-hydroxy-5-methyl-2-(propan-2-yl)hex-5-en-3-ynoate, (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-5-methyl-2-propan-2-ylhex-5-en-3-ynoate, 101564-58-3. CAS No. 101564-58-3. Molecular formula: C18H27NO3. Mole weight: 305.412 g/mol. Purity: 0.96. IUPACName: (2-methyl-1-azabicyclo[2.2.2]octan-3-yl) 2-hydroxy-5-methyl-2-propan-2-ylhex-5-en-3-ynoate. Canonical SMILES: CC1C (C2CCN1CC2)OC (=O)C (C#CC (=C)C) (C (C)C)O. Density: 1.1g/cm³. Catalog: ACM101564583. | |
| Aceclidine | Aceclidine is an agent that is used for treating glaucoma by reducing intraocular pressure. Aceclidine is a modulator of M3 muscarinic acetylcholine receptor. Synonyms: Quinuclidin-3-yl acetate; 3-Acetoxyquinuclidine; Glaucostat; 3-Quinuclidinol acetate (ester); NSC 657843. CAS No. 827-61-2. Molecular formula: C9H15NO2. Mole weight: 169.22. | |
| Aceclidine | Aceclidine (Quinuclidin-3-yl acetate) is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC 50 : 40 μM). Aceclidine is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Quinuclidin-3-yl acetate. CAS No. 827-61-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-32067. | |
| Aceclidine hydrochloride | Aceclidine (Quinuclidin-3-yl acetate) hydrochloride is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC 50 : 40 μM). Aceclidine hydrochloride is a cycloplegic agent, a surfactant, a tonicity adjustor and optionally a viscosity enhancer and an antioxidant. Aceclidine hydrochloride has the potential for the research of disorders such as refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Quinuclidin-3-yl acetate hydrochloride. CAS No. 6109-70-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-32067A. | |
| APR-246 | APR-246 is a quinuclidinone derivative that targets the Wrap53 gene with potential antineoplastic activity. This agent may work synergistically with other antineoplastic agents. The Wrap53 transcript, a natural p53 antisense transcript, regulates endogenous p53 mRNA levels and additional induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Synonyms: PRIMA-1MET; Prima 1MET; Eprenetapopt; 2-(Hydroxymethyl)-2-(methoxymethyl)quinuclidin-3-one. Grades: 98%. CAS No. 5291-32-7. Molecular formula: C10H17NO3. Mole weight: 199.25. | |
| (+)-Azasetron hydrochloride | The (+)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist. Uses: Antiemetics. Synonyms: azasetron hydrochloride; 123040-16-4; Azasetron HCl; 123040-69-7; Serotone; Y-25130 hydrochloride; 141922-90-9; Azasetron (hydrochloride); AZASETRONHYDROCHLORIDE; Azasetron hydrochloride [JAN]; D-erythro-Sphingosine (Brain, Porcine); 123040-93-7; 477243-03-1; 123040-96-0; 2BSS7XL60S; 123040-94-8; Y-25130 HCl; 2H-1,4-Benzoxazine-8-carboxamide, N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-, hydrochloride (1:1); N-(1-azabicyclo[2.2.2]octan-3-yl)-6-chloro-4-methyl-3-oxo-1,4-benzoxazine-8-carboxamide; hydrochloride; 6-chloro-4-methyl-3-oxo-N-(quinuclidin-3-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carboxamide hydrochloride; Azasetron hydrochloride (JAN); Y-25130; 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-,monohydrochloride, (+)-; 2H-1,4-Benzoxazine-8-carboxamide,N-1-azabicyclo[2.2.2]oct-3-yl-6-chloro-3,4-dihydro-4-methyl-3-oxo-,monohydrochloride,n. Grades: 99%. CAS No. 123040-94-8. Molecular formula: C17H20ClN3O3.HCl. Mole weight: 386.27. | |
| Bradanicline hydrochloride | Bradanicline hydrochloride is Alpha-7 Nicotinic Receptor Agonist. It showed cognitive enhancing effects in animal studies, and was being developed as a potential treatment for schizophrenia and attention deficit disorder. It was discontinued for Alzheimer's disease and cognitive impairment in schizophrenia in late 2013. It was also discontinued for ADHD, and no longer seems to be being developed. Uses: Bradanicline hydrochloride was being developed as a potential treatment for schizophrenia and attention deficit disorder. Synonyms: TC-5619;TC5619;TC-5619-023;TC5619-023;N-((2S,3R)-2-(pyridin-3-ylmethyl)quinuclidin-3-yl)benzofuran-2-carboxamide hydrochloride. Grades: >98%. CAS No. 1111941-90-2. Molecular formula: C22H24ClN3O2. Mole weight: 397.90. | |
| Cevimeline-d4 Hydrochloride Salt | A labeled muscarinic M1 and M3 receptor agonist. Sialagogue. Group: Biochemicals. Alternative Names: (+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3-quinuclidine-d4 Hydrochloride; AF-102B-d4 Hydrochloride; SNI-2011-d4 Hydrochloride; Evoxac-d4 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cevimeline hydrochloride | Cevimeline hydrochloride (AF102B hydrochloride) is a quinuclidine derivative of acetylcholine and a selective and orally active muscarinic M1 and M3 receptor agonist. Cevimeline hydrochloride stimulates secretion by the salivary glands and can be used as a sialogogue for xerostomia [1] [2] [3] [4]. Cevimeline hydrochloride can cross the blood-brain barrier (BBB) [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AF102B hydrochloride. CAS No. 107220-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-70020B. | |
| Cevimeline hydrochloride salt | Cevimeline hydrochloride salt. Group: Biochemicals. Alternative Names: (+/-)-cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine; AF-102B; SNI-2011. Grades: Highly Purified. CAS No. 107220-28-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C10H18ClNOS. US Biological Life Sciences. | Worldwide |
| Cevimeline hydrochloride salt | Heterocyclic Organic Compound. Alternative Names: CEVIMELINE, HYDROCHLORIDE SALT;Fks 508;Saligren;Snd 5008;cis-2-Methylspiro[1, 3-oxathiolane-5, 3-quinuclidine]hydrochloride;(2R, 3R)-rel-2-Methyl- spiro[1-azabicyclo[2.2.2]octane-3,5-[1,3]oxathiolane] hydrochloride;SNK 508;CeviMelin. CAS No. 107220-28-0. Molecular formula: C10H18ClNOS. Mole weight: 235.77402. Catalog: ACM107220280. | |
| Coluracetam | MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholine mustard aziridinium ion (AF64A) treated rats, but not of normal rats. MKC-231 did not affect the AChE activity, [3H]- quinuclidinyl benzilate binding, and [3H]-pirenzepine binding. Oral administration of MKC-231 (1-10 mg/kg) significantly improved the learning deficits in the Morris' water maze of AF64A-treated rats, but it did not produce any significant side effects, like tremor, salivation or hypothermia, which were observed in rats treated with high doses of tacrine [1]. In acute behavioral experiments, MKC-231 and THA had no significant effect on AF64A-induced memory deficits at any doses tested (0.3, 1.0 and 3.0 mg/kg), whereas Dup 996, at a dose of 1.0 mg/kg, significantly improved memory deficits. In chronic experiments, MKC-231 improved memory deficit at all doses tested (0.3, 1.0, or 3.0 mg/kg p.o., once daily for 11 days) and Dup 996 did so only at a dose of 3.0 mg/kg, whereas THA did not improve memory deficit at any doses tested. Synonyms: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231. Grades: >98%. CAS No. 135463-81-9. Molecular formula: C19H23N3O3. Mole weight: 341.4. | |
| Desoxy-Palonosetron Dihydrochloride | Desoxy-Palonosetron Dihydrochloride is a derivative of Palonosetron, which is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Synonyms: (S)-2-((S)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline dihydrochloride. Grades: ≥95%. Molecular formula: C19H28Cl2N2. Mole weight: 355.34. | |
| Encenicline, HCl salt | EVP-6124, its alpha-7 nicotinic acetylcholine receptor agonist, possesses a novel mechanism not previously seen in the scientific community: it acts as a co-agonist with Acetylcholine (ACh) to enhance cognition. By acting as a co-agonist and sensitizing the alpha-7 receptor, EVP-6124 makes it possible for smaller amounts of naturally occurring ACh, typically found in individuals with memory disorders such as Alzheimer's, to be required to activate the receptor. In this scenario, research demonstrated that memory deficits can be minimized or entirely reversed by controlling the neuronal channel with EVP-6124 alone or in combination with other Alzheimer's drugs. Synonyms: EVP-6124; EVP 6124; EVP6124; MT-4666; MT 4666; MT4666; Encenicline. IUPAC/Chemical name:(R)-7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide hydrochloride. Grades: 0.98. CAS No. 550999-74-1. Molecular formula: C16H18Cl2N2OS. Mole weight: 357.293. | |
| Espatropate | Espatropate is a Muscarinic receptor antagonist originated by Pfizer. It is a bronchodilator with antimuscarinic activity. No development was reported for the treatment of Asthma. Uses: Asthma. Synonyms: UK-88060; UNII-13MIU3750H; UK 88060; UNII 13MIU3750H; UK88060; UNII13MIU3750H; (R)-3-Quinuclidinyl (R)-alpha-(hydroxymethyl)-alpha-phenylimidazole-1-acetate. Grades: 98%. CAS No. 132829-83-5. Molecular formula: C19H23N3O3. Mole weight: 341.41. | |
| Facinicline | Facinicline is a partial agonist of the nicotinic alpha-7 (α7) receptor. It is used for the oral treatment of Alzheimer's. It was being co-developed by Roche and was in clinic phase 2 trials with no progress. Uses: Facinicline is used for the oral treatment of alzheimer's. Synonyms: Facinicline; RG-3487; MEM-3454; R-3487; RO-5313534; RG3487; MEM3454; R-487; RO5313534; RG 3487; MEM 3454; R 3487; RO 5313534; (S)-N-(quinuclidin-3-yl)-1H-indazole-3-carboxamide;N-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-1H-indazole-3-carboxamide. Grades: 98%. CAS No. 677306-35-3. Molecular formula: C15H18N4O. Mole weight: 270.34. | |
| Mequitazine | Mequitazine, an antihistamine, is a potent, nonsedative and long-acting histamine H1 antagonist. Synonyms: 10-(1-Azabicyclo[2.2.2]oct-3-ylmethyl)-10H-phenothiazine; 10-(3-Quinuclidinylmethyl)phenothiazine; Butix; LM 209; Metaplexan; Mircol; NSC 303612; Nipolazin; Primalan; Quitadrill; Zesulan. Grades: ≥95%. CAS No. 29216-28-2. Molecular formula: C20H22N2S. Mole weight: 322.47. | |
| Mequitazine Impurity 1 | Synonyms: 3-((10H-phenothiazin-10-yl)Methyl)quinuclidin-3-ol. Grades: > 95%. CAS No. 144827-80-5. Molecular formula: C20H22N2OS. Mole weight: 338.47. | |
| Metixene hydrochloride hydrate | Metixene (Piperidine) hydrochloride hydrate is an anticholinergic and antiparkinsonian agent. Metixene hydrochloride hydrate potently inhibits binding of quinuclidinyl benzilate (QNB) with the muscarinic receptor, IC 50 and K i values of 55 nM and 15 nM, respectively. Metixene hydrochloride hydrate can be used for the research of parkinsonian [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7081-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120081A. | |
| N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide | N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-5,6-dihydro-1-Naphthalenecarboxamide is an impurity of Palonosetron, which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. Synonyms: (S)-N-(Quinuclidin-3-yl)-5,6-dihydronaphthalene-1-carboxamide; (R)-N-(((S)-1-methyl-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)quinuclidin-3-amine. CAS No. 1227162-75-5. Molecular formula: C18H22N2O. Mole weight: 282.38. | |
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