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Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets ( iGluR and mGluR ) of excitatory amino acid (EAA) agonist with an EC 50 of 45 nM and a K i of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Quisqualic acid. CAS No. 52809-07-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-12597.
A potent agonist highly selective for group I (EC50 ≤3uM) over group II and III mGlu receptors (EC50 >40uM) and a potent agonist of AMPA receptors. Often used for inducing excitotoxic lesions of basal forebrain cholinergic neurons and spinal neurons.CAS Number:52809-07-1. Group: Biochemicals. Grades: Highly Purified. CAS No. 52809-07-1. Pack Sizes: 1mg. US Biological Life Sciences.
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L-Quisqualic acid
L-Quisqualic acid. Group: Biochemicals. Grades: Purified. CAS No. 52809-07-1. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences.
Worldwide
L-Quisqualic acid
L-Quisqualic acid is a glutamate receptor agonist acting at AMPA receptors and mGluR positively linked to phosphoinositide hydrolysis. L-Quisqualic acid was shown to induce a slow K(+)-current response in B6 neurons of Aplysia buccal ganglia. It exhibits neuroprotective property and may be beneficial for prostate cancer therapy. Synonyms: (L)-(+)-α-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid; (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid. Grades: ≥99% by HPLC. CAS No. 52809-07-1. Molecular formula: C5H7N3O5. Mole weight: 189.13.
L-Quisqualic acid
L-Quisqualic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(3,5-DIOXO-1,2,4-OXADIAZOLIDIN-2-YL)-L-ALANINE;L(+)-QUISQUALIC ACID;L-QUISQUALIC ACID;L-(+)-A-AMINO-3,5-DIOXO-1,2,4-OXADIAZOLIDINE-2-PROPANOIC ACID;(L)-(+)-ALPHA-AMINO-3,5-DIOXO-1,2,4-OXADIAZOLIDINE-2-PROPANOIC ACID;BETA-[3,5-DIOXO-1,2,4-OXADIAZOLIDIN-. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 52809-07-1. Molecular formula: C5H7N3O5. Mole weight: 189.13. Purity: >99 %. Density: 1.679g/cm³. Product ID: ACM52809071. Alfa Chemistry ISO 9001:2015 Certified.
(+)-Quisqualic acid
(+)-Quisqualic acid. Group: Biochemicals. Alternative Names: L-(+)-a-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid; L-Quisqualic acid. Grades: Highly Purified. CAS No. 52809-07-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C5H7N3O5. US Biological Life Sciences.
Worldwide
glutamate carboxypeptidase II
A metallo-carboxypeptidase that is predominantly expressed as a membrane-bound enzyme of 94-100 kDa, but also exists in a soluble form. Hydrolyses α-peptide bonds in Ac-Asp-Glu, Asp-Glu, and Glu-Glu, but also γ-glutamyl bonds in γ-Glu-Glu, and folylpoly-γ-glutamates. With folylpoly-γ-glutamates, shows processive carboxypeptidase activity to produce pteroylmonoglutamate. Does not hydrolyse Ac-β-Asp-Glu. Known inhibitors: quisqualic acid, Ac-β-Asp-Glu, and 2-phosphonomethyl-pentanedioate. In peptidase family M28 of Vibrio leucyl aminopeptidase. The release of C-terminal glutamate from folylpoly-γ-glutamates is also catalysed by EC 3.4.17.11 (glutamate carboxypeptidase) and EC 3.4.19.9 (γ-Glu-X carboxypeptidase). Group: Enzymes. Synonyms: N-acetylated-γ-linked-acidic dipeptidase (NAALADas. Enzyme Commission Number: EC 3.4.17.21. CAS No. 9074-87-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4074; glutamate carboxypeptidase II; EC 3.4.17.21; 9074-87-7; N-acetylated-γ-linked-acidic dipeptidase (NAALADase); folate hydrolase; prostate-specific membrane antigen; pteroylpoly-γ-glutamate carboxypeptidase; microsomal γ-glutamyl carboxypeptidase; pteroylpolyglutamate hydrolase; folylpolyglutamate h
D-AP4
D-AP4 has been found to be an excitatory amino acid receptor antagonist as well as an agonist at the quisqualate-sensitized AP6 site. Synonyms: D-AP4; D AP4; DAP4; D-(-)-2-Amino-4-phosphonobutyric acid. Grades: ≥98% by HPLC. CAS No. 78739-01-2. Molecular formula: C4H10NO5P. Mole weight: 183.10.
Ibotenic acid
Ibotenic acid has agonist activity at both the N-methyl-D-aspartate ( NMDA ) and trans-ACPD or metabolotropic quisqualate (Q m ) receptor sites. Uses: Scientific research. Group: Natural products. Alternative Names: (RS)-Ibotenic acid; DL-Ibotenic acid. CAS No. 2552-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2311.
L-AP4
L-AP4 is a selective group III metabotropic glutamate receptor (mGluR) agonist. It also acts as an agonist at the quisqualate-sensitized AP6 site in hippocampus. L-AP4 is a synaptic depressant. Synonyms: L-(+)-2-Amino-4-phosphonobutyric acid; (2S)-2-amino-4-phosphonobutanoic acid; L-AP4; L AP4; LAP4. Grades: ≥99% by HPLC. CAS No. 23052-81-5. Molecular formula: C4H10NO5P. Mole weight: 183.1.
L-AP5
L-AP5 has been found to be an NMDA antagonist as well as a quisqualate-sensitized AP6 site agonist. Synonyms: L-(+)-2-Amino-5-phosphonopentanoic acid. Grades: ≥99% by HPLC. CAS No. 79055-67-7. Molecular formula: C5H12NO5P. Mole weight: 197.13.
L-Glutamic Acid Monosodium Salt
Sodium Glutamate is an agonist at kainate, quisqualate and NMDA receptors. Synonyms: L-Glutamic Acid Monosodium Salt; Monosodium L-Glutamate; MSG. CAS No. 142-47-2. Molecular formula: C5H8NNaO4. Mole weight: 169.11.
LY 367385
LY 367385 is a selective mGlu1a receptor antagonist with an IC50 value of 8.8 μM for blockade of quisqualate-induced phosphoinositide hydrolysis. LY 367385 is used to treat inflammatory diseases and neurodegenerative diseases. Synonyms: LY367385; LY 367385; LY-367385; (S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid; 4-[(S)-Amino(carboxy)methyl]-3-methylbenzoic acid. Grades: ≥99% by HPLC. CAS No. 198419-91-9. Molecular formula: C10H11NO4. Mole weight: 209.2.
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