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DO2A-tert-butyl ester is a bifunctional chelator ( BFC ) that can be used for the coupling of peptides and radionuclides. DO2A-tert-butyl ester can be used in the development of radionuclide imaging tracers [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 162148-48-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W283556.
DOTATATE
DOTATATE is a DOTA-conjugated peptide. DOTATATE can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [1] [2] [3] [4]. DOTATATE can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 177943-88-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-106244.
DOTATATE acetate
DOTATATE acetate is a DOTA-conjugated peptide. DOTATATE acetate can be labelled with radionuclides for positron emission tomography (PET) imaging and peptide receptor radionuclide research (PRRT) [1] [2] [3] [4]. DOTATATE (acetate) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 177943-89-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106244A.
DOTA-[Tyr3]-Octreotide Acid
DOTA-TATE, DOTATATE or DOTA-octreotate is a substance which, when bound to various radionuclides, has been tested for the treatment and diagnosis of certain types of cancer, mainly neuroendocrine tumours. Synonyms: DOTATATE; DOTA-(Tyr3,Thr8)-Octreotide; DOTA-[Tyr3] Octreotide Acid (Octreotate); 4,7,10-Tricarboxymethyl-1,4,7,10-tetraaza-cyclododecan-1-yl-acetyl-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-OH acetate salt (Disulfide bond). Grades: 98%. CAS No. 177943-89-4. Molecular formula: C65H90N14O19S2. Mole weight: 1435.63.
DTPA (Pentetic Acid)
Pentetic acid is mainly used as a chelating agent in the preparation of imaging and as a contrast agent for radionuclides and magnetic resonance imaging. Uses: Chelating agents. Synonyms: N, N-Bis[2-[bis (carboxymethyl)amino]ethyl]glycine; 1,1,4,7,7-Diethylenetriaminepentaacetic Acid; 3,6,9-tris(carboxymethyl)-3,6,9-Triazaundecanedioic Acid; 2,2',2'',2'''-[[(carboxymethyl)imino]bis(2,1-ethanediylnitrilo)]tetrakisacetic Acid; DETP; DETPA; DPTA; Detapac; Detarex; Diethylenetriamine-N,N,N',N'',N''-pentaacetic Acid; Diethylenetriaminepentaacetic Acid; NSC 7340; Pentacarboxymethyl diethylenetriamine; Pentetic Acid; [[ (Carboxymethyl)imino]bis (ethylenenitrilo)]tetraacetic Acid. Grades: >95%. CAS No. 67-43-6. Molecular formula: C14H23N3O10. Mole weight: 393.35.
Edotreotide
Edotreotide is a somatostatin analogue. Edotreotide bound to various radionuclides, has the potential for the research and diagnosis of certain types of cancer [1]. Edotreotide can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. Alternative Names: DOTATOC; SDZ-SMT 487; SMT 487. CAS No. 204318-14-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106033.
Macropa
Macropa is a macrocyclic chelator that can be used as radionuclides to study soft tissue metastases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128304-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160131.
p-SCN-Bn-DOTA
p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127985-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114377.
Rofapitide tetraxetan
Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC 50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-147057.
(S)-p-SCN-Bn-DOTA
(S)-p-SCN-Bn-DOTAis a bifunctional chelator ( Bifunctional Chelator ; BFC ) and a macrocyclic DOTA derivative used for tumor pre-targeting. (S)-p-SCN-Bn-DOTA can be used for conjugation of peptides and radionuclides. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1020407-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156038.
DOTA-LM3
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis[1][2]. DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 1192362-32-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5126.
DPI-4452
DPI-4452 is a CAIX -targeting cyclic peptide with a DOTA cage, and can be chelated with radionuclide for CAIX-expressing tumor PET-CT imaging and study. DPI-4452 specifically and selectively binds CAIX without interaction with an in vitro off-target receptor panel of 55 targets ( IC 50 for recombinant hCAIX: 130 nM). Radiolabeled DPI-4452 inhibits tumor growth in HT-29 and SK-RC-52 xenograft mouse models [1]. DPI-4452 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 2941391-49-5. Pack Sizes: 1 mg. Product ID: HY-P10761.
FAPI-mFS
FAPI-mFS is an irreversible fibroblast activation protein (FAP) inhibitor, that enhances the uptake and retention time in cancer cells through its covalent binding property for FAP. FAPI-mFS can be used for cancer imaging the therapy, when labeled with radioactive 68Ga or 177Lu[1]. FAPI-mFS can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 3023869-94-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164725.
Flobetapir
Flobetapir (AV-45) may be a well-tolerated imaging agent. Flobetapir synthesizes Florbetapir (18F) that is a PET scanning radiopharmaceutical compound containing the radionuclide fluorine-18 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-45. CAS No. 938435-69-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129650.
γ-Tocotrienol
γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a novel radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 14101-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-108694.
Pentixafor
Pentixafor is a peptide that targets CXCR4. Pentixafor is capable of being labelled with 68 Gallium ( 68 Ga) for positron emission tomography (PET) imaging [1] [2] [3] [4]. Pentixafor can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 1341207-62-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153549.
Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups. Dendrimers are chemically modified by attaching poly ethylene glycol (PEG) molecule to increase its solubility and prolong circulation half-life."Clickable groups", such as primary acetylenes, are introduced to the mono dispersed dendritic structures, using "click" chemistry. These acetylene groups, attached to Bis-MPA based dendrons, allow it to form the conjugates with bioactive moieties such as carbohydrate, fluorescent dyes, disaccharides etc. Uses: The proposed uses are: as an efficient drug delivery system. in vitro toxicological studies; in vivo via radionuclide labeling and optical imaging biosensors;dip pen nanolithography. Group: Dendrimers. Alternative Names: PFD-G3-PEG6k-Acetylene, Dendron functionalized PEG acetylene, generation 3, Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, PEG-6000, Bis-MPA poly(ethylene glycol). Pack Sizes: Packaging 500 mg in glass insert. Molecular formula: PEG average Mn 6000 (n~130, esterified with 16 acetylene groups) Mn 7500-9500 (by NMR) average Mn 8000.
PSMA-1007
PSMA-1007 is a prostate-specific membrane antigen ( PSMA ) ligand. 18 F-labeled PSMA-1007 can be used as a PET tracer for prostate cancer imaging [1]. PSMA-1007 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 2226894-58-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153550.
PSMA I&T
PSMA I&T is an effective inhibitor of prostate-specific membrane antigen ( PSMA ). PSMA I&T can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2192281-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148761.
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