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Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. Group: Inhibitors. Alternative Names: Raltegravir; N-((4-Fluorophenyl)methyl)-1, 6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1, 3, 4-oxadiazol-2-yl)carbonyl)amino)ethyl)-6-oxo-4-pyrimidinecarboxamide; N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1, 6-dihydropyrimidin-2-yl)propan-2-yl)-5-methyl-1, 3, 4-oxadiazole-2-carboxamide; N-(2-(4-(4-Fluorobenzylcarbamoyl)-5-hydroxy-1-methyl-6-oxo-1, 6-dihydropyrimidin-2-yl)p; Raltegravir(R&D); Raltegravir(free base);N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(2-(2-methyl-1,3,4-oxadiazole-5-carboxamido)propan-2-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide;N-((4-Fluorophenyl)methyl)-1,6-dihydro-5-hydroxy-1-methyl-2-(1-methyl-1-(((5-methyl-1,3,4-oxadiazol-2-yl)carbonyl)am. CAS No. 518048-05-0. Molecular formula: C20H21FN6O5. Mole weight: 444.42. Appearance: Solid. Purity: 0.9953. Canonical SMILES: O=C (C (O)=C (C (NCC1=CC=C (C=C1)F)=O)N=C2C (C) (C)NC (C3=NN=C (C)O3)=O)N2C. Catalog: ACM518048050.
Raltegravir
Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0518. CAS No. 518048-05-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10353.
Protected labeled metabolite of Raltegravir. Group: Biochemicals. Alternative Names: 4-[[[ (4-Fluorophenyl) methyl]amino]carbonyl]-1, 6-dihydro-1- (methyl-d3) -2-[1-methyl-1-[[ (5-methyl-1, 3, 4-oxadiazol-2-yl) carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Raltegravir b-D-glucuronide methyl ester
Raltegravir b-D-glucuronide methyl ester is an invaluable pharmaceutical compound extensively applied in the biomedical industry, exhibiting profound application in studying human immunodeficiency virus (HIV) infections. It is renowned for its ability to inhibit HIV integrase enzyme. Synonyms: 4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl-D-Glucopyranosiduronic Acid Methyl Ester. Molecular formula: C27H31FN6O11. Mole weight: 634.57.
Raltegravir β-D-Glucuronide
A metabolite of Raltegravir.Raltegravir is an integrase inhibitor as antiretroviral drug. It can be used for the treatment of HIV infection. Synonyms: 4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 952654-62-5. Molecular formula: C26H29FN6O11. Mole weight: 620.54.
Raltegravir β-D-Glucuronide Methyl Ester-d3
Protected, labeled metabolite of Raltegravir. Group: Biochemicals. Alternative Names: 4-[[[ (4-Fluorophenyl) methyl]amino]carbonyl]-1, 6-dihydro- (1-methyl-d3) -2-[1-methyl-1-[[ (5-methyl-1, 3, 4-oxadiazol-2-yl) carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Raltegravir-d3 β-D-Glucuronide
A labeled metabolite of Raltegravir. Group: Biochemicals. Alternative Names: 4-[[[ (4-Fluorophenyl) methyl]amino]carbonyl]-1, 6-dihydro-1-methyl-2-[1-methyl-1-[[ (5-methyl-1, 3, 4-oxadiazol-2-yl) carbonyl]amino]ethyl]-6-oxopyrimidin-5-yl. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Raltegravir-d3 Potassium Salt
A potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Alternative Names: N-[ (4-Fluorophenyl) methyl]-1, 6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[ (5-methyl-1, 3, 4-oxadiazol-2-yl) carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide-d3 Potassium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Raltegravir EP impurity C
Raltegravir EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391918-17-4. Molecular Formula: C20H23FN6O6. Mole Weight: 462.44. Catalog: APB1391918174.
Raltegravir potassium
Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 0518 potassium. CAS No. 871038-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10353A.
Raltegravir Potassium Salt
A potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Alternative Names: N-[ (4-Fluorophenyl) methyl]-1, 6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[ (5-methyl-1, 3, 4-oxadiazol-2-yl) carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide Potassium Salt. Grades: Highly Purified. CAS No. 871038-72-1. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Raltegravir Potassium Salt
Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridine diphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents. Uses: Anti-hiv agents. Synonyms: MK-0518; MK 0518; MK0518; Raltegravir. Grades: 98%. CAS No. 871038-72-1. Molecular formula: C20H20FKN6O5. Mole weight: 482.514.
Raltegravir Potassium Salt
Raltegravir Potassium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 871038-72-1. Molecular Formula: C20H20FN6O5·K. Mole Weight: 482.511. Catalog: APB871038721.
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir is an impurity of a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1391918-17-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C20H23FN6O6. US Biological Life Sciences.
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-Amino-2-oxoacetic Acid) Raltegravir is a derivative of Raltegravir (R100300), a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1064706-98-4. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C18H19FN4O6. US Biological Life Sciences.
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) (E)-2-(N,N-Dimethylformimidamide) Raltegravir is an impurity of Raltegravir (R100300), a potent human immunodeficiency virus (HIV) integrase inhibitor. A novel anti-AIDS drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 1193687-85-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C19H24FN5O3. US Biological Life Sciences.
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) (E)-2-(N,N-Dimethylformimidamide) Raltegravir. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS004324. Format: Neat. Shipping: Room Temperature.
4-Defluoro Raltegravir
An impurity of Raltegravir. Raltegravir is an integrase inhibitor as an antiretroviral drug. It can be used for the treatment of HIV infection. Synonyms: 1,6-Dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-N-(phenylmethyl)-4-pyrimidinecarboxamide. Grades: > 95%. CAS No. 1193687-87-4. Molecular formula: C20H22N6O5. Mole weight: 426.44.
1,3-Oxazinan-2-one
1,3-Oxazinan-2-one is a reactant used in the preparation of HIV integrase inhibitors active against raltegravir resistant strains. Group: Biochemicals. Grades: Highly Purified. CAS No. 5259-97-2. Pack Sizes: 500mg, 5g. Molecular Formula: C4H7NO2, Molecular Weight: 101.1. US Biological Life Sciences.
An impurity of the commercial synthesis of Raltegravir. Group: Biochemicals. Alternative Names: 5-Hydroxy-6-methoxy-2-[1-methyl-1-[[ (phenylmethoxy) carbonyl]amino]ethyl]-4-pyrimidinecarboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1159977-42-0. Pack Sizes: 25mg. US Biological Life Sciences.
An labeled impurity of the commercial synthesis of labeled Raltegravir. Group: Biochemicals. Alternative Names: 5-Hydroxy-6- (methoxy-d3) -2-[1-methyl-1-[[ (phenylmethoxy) carbonyl]amino]ethyl]-4-pyrimidinecarboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 1185032-53-4. Pack Sizes: 1mg. US Biological Life Sciences.
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Dolutegravir (GSK1349572)
Dolutegravir is a two-metal-binding HIV-1 integrase inhibitor with IC50 of 2.7 nM, with modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. It blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). Synonyms: GSK-1349572; GSK 1349572; GSK1349572; Tivicay. Grades: ≥98%. CAS No. 1051375-16-6. Molecular formula: C20H19F2N3O5. Mole weight: 419.38.
Dolutegravir sodium
Dolutegravir sodium salt is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. Uses: Hiv integrase inhibitors. Synonyms: DTG; GSK1349572; GSK 1349572; GSK-1349572. Grades: >98%. CAS No. 1051375-19-9. Molecular formula: C20H18F2N3NaO5. Mole weight: 441.36.
MK-2048
MK-2048 is a second generation integrase inhibitor (IC50=2.6 nM). It can inhibits the HIV enzyme integrase 4 times longer than raltegravir. Synonyms: MK2048; MK 2048; MK-2048. Grades: >98%. CAS No. 869901-69-9. Molecular formula: C22H24FN5O4. Mole weight: 441.46.
MK-2048
MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir. MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir. Group: Biochemicals. Alternative Names: (6S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N, 6-dimethyl-1, 9-dioxo-1, 2, 6, 7, 8, 9-hexahydropyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyridazine-4-carboxamide. Grades: Highly Purified. CAS No. 869901-69-9. Pack Sizes: 5mg. US Biological Life Sciences.
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