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Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current ( I Na and I Kr with IC 50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) [1] [2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor [3]. Antianginal agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT 303; RS 43285-003. CAS No. 95635-55-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0280.
Ranolazine
Ranolazine is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina. Synonyms: CVT 303; RS 43285-003; CVT303; RS43285-003; CVT-303; RS-43285-003. Grade: >98%. CAS No. 95635-55-5. Molecular formula: C24H33N3O4. Mole weight: 427.54.
Ranolazine
Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Antianginal. Group: Biochemicals. Grades: Highly Purified. CAS No. 95635-55-5. Pack Sizes: 10mg, 100mg, 200mg, 500mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences.
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Ranolazine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardspharmaceutical toxicology. Alternative Names: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide, CVT 303, (+/-)-Ranolazine, Renexa, RS 43285-003, Ranexa, 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, (+/-)-, Ranolazine.
Ranolazine-d3
Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Antianginal. Group: Biochemicals. Alternative Names: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxy-d3-phenoxy)propyl]-1-piperazineacetamide; RS 43285-d3; RS 43285-193-d3. Grades: Highly Purified. CAS No. 1054624-77-9. Pack Sizes: 1mg. US Biological Life Sciences.
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Ranolazine-[d3]
Ranolazine-[d3] is the labelled analogue of Ranolazine, which is an anti-ischemic agent. Uses: Anti-ischemic agent which modulates myocardial metabolism. antianginal. Synonyms: Ranolazine D3. Grade: 95% atom D. CAS No. 1054624-77-9. Molecular formula: C24H30D3N3O4. Mole weight: 430.26.
Ranolazine-[d8]
Ranolazine-[d8] is a labelled Ranolazine. Ranolazine is a medication appoved for the treatment of chronic angina. Synonyms: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazine-2,2,3,3,5,5,6,6-d8-acetamide. Grade: 99% HPLC; 98% atom D. CAS No. 1092804-88-0. Molecular formula: C24H25D8N3O4. Mole weight: 435.59.
Ranolazine-[d8] dihydrochloride (piperazine-[d8])
Ranolazine-[d8] Dihydrochloride is the labelled compound of Ranolazine Dihydrochloride, an anti-ischemic agent which modulates myocardial metabolism. Antianginal. Synonyms: N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl](D8)piperazin-1-yl}acetamide Dihydrochloride; [2H8]-Ranolazine dihydrochloride; (±)-N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamided-d8 Dihydrochloride. Grade: 95% by HPLC; 98% atom D. CAS No. 1219802-60-4. Molecular formula: C24H27D8Cl2N3O4. Mole weight: 508.51.
Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina. Grade: >98%. CAS No. 95635-56-6. Molecular formula: C24H35Cl2N3O4. Mole weight: 500.46.
Ranolazine dihydrochloride
Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current ( I Na and I Kr with IC 50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) [1] [2]. Ranolazine dihydrochloride is also a partial fatty acid oxidation inhibitor [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT 303 dihydrochloride; RS 43285. CAS No. 95635-56-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-17401.
Ranolazine dihydrochloride
Ranolazine dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 95635-56-6. Pack Sizes: 50mg. US Biological Life Sciences.
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Ranolazine Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ranolazine Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ranolazine Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ranolazine Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
1,2-O-(1-Ranolazineethylidene)-4,5-di-O-acetyl-α-D-galactopyranuronic Acid Methyl Ester is one of Ranolazine derivatives. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Synonyms: (3aR,5S,6S,7S,7aR)-2-((1-(4-(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)piperazin-1-yl)-3-(2-methoxyphenoxy)propan-2-yl)oxy)-5-(methoxycarbonyl)-2-methyltetrahydro-5H-[1,3]dioxolo[4,5-b]pyran-6,7-diyl diacetate. Molecular formula: C37H49N3O13. Mole weight: 743.80.
Desmethoxy Ranolazine
Desmethoxy Ranolazine is the desmethoxy analogue of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: N-(2,6-Dimethylphenyl)-4-(2-hydroxy-3-phenoxypropyl)-1-piperazineacetamide; Ranolazine Related Compound B. Grade: 98%. CAS No. 755711-09-2. Molecular formula: C23H31N3O3. Mole weight: 397.51.
Desmethyl Ranolazine
A metabolite of Ranolazine. Group: Biochemicals. Alternative Names: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]-1-piperazineacetamide; RS 88390. Grades: Highly Purified. CAS No. 172430-45-4. Pack Sizes: 1mg. US Biological Life Sciences.
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Desmethyl Ranolazine
Desmethyl Ranolazine is one of ranolazine metabolites. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Uses: A metabolite of ranolazine (r122500). Synonyms: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]-1-piperazineacetamide; RS 88390; 1-Piperazineacetamide,N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl]. Grade: 98%. CAS No. 172430-45-4. Molecular formula: C23H31N3O4. Mole weight: 413.51.
Desmethyl Ranolazine β-D-Glucuronide (mixture of diastereomers)
Desmethyl Ranolazine β-D-Glucuronide (mixture of diastereomers) is one of Ranolazine metabolites. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Synonyms: 2-[3-[4-[2-[(2,6-Dimethylphenyl)amino]-2-oxoethyl]-1-piperazinyl]-2-hydroxypropoxy]phenyl β-D-glucopyranosiduronic acid; Des-O-methyl-o-glucuronide-ranolazine. Grade: 98%. CAS No. 172300-93-5. Molecular formula: C29H39N3O10. Mole weight: 589.63.
Desmethyl Ranolazine-d5
A labeled metabolite of Ranolazine. Group: Biochemicals. Alternative Names: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-hydroxyphenoxy)propyl-d5]-1-piperazineacetamide; RS 88390-d5. Grades: Highly Purified. CAS No. 1329834-18-5. Pack Sizes: 1mg. US Biological Life Sciences.
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O-Desaryl Ranolazine
A metabolite of Ranolazine. Group: Biochemicals. Alternative Names: 4-(2,3-Dihydroxypropyl)-N-(2,6-dimethylphenyl)-1-piperazineacetamide; RS 88640;CVT-2512. Grades: Highly Purified. CAS No. 172430-46-5. Pack Sizes: 1mg. US Biological Life Sciences.
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p-Ranolazine
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
(R)-Ranolazine
(R)-Ranolazine is the R-isomer of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[(2R)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-; (R)-N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide; (+)-Ranolazine. Grade: ≥95%. CAS No. 114246-80-9. Molecular formula: C24H33N3O4. Mole weight: 427.54.
(R,S)-Ranolazine O-β-D-glucuronide
(R,S)-Ranolazine O-β-D-glucuronide is a metabolite of Ranolazine. Ranolazine is a medication appoved for the treatment of chronic angina. Synonyms: Ranolazine O-β-D-glucuronide; N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide O-β-D-glucuronide; (±)-Ranolazine O-β-D-glucuronide; 4-(Pyrimidin-2-ylmethyl)-7-(4-(trifluoromethyl)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one O-β-D-glucuronide; (2S,3S,4S,5R,6R)-6-((1-(4-(2-((2,6-Dimethylphenyl)amino)-2-oxoethyl)piperazin-1-yl)-3-(2-methoxyphenoxy)propan-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: ≥95%. Molecular formula: C30H41N3O10. Mole weight: 603.66.
(S)-Ranolazine
(S)-Ranolazine is the S-isomer of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-; N-(2,6-Dimethylphenyl)-2-{4-[(2S)-2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazinyl}acetamide; (-)-Ranolazine. Grade: ≥95%. CAS No. 114246-81-0. Molecular formula: C24H33N3O4. Mole weight: 427.54.
1-(2-Methoxyphenoxy)-3-chloro-2-propanol
1-(2-Methoxyphenoxy)-3-chloro-2-propanol is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Synonyms: 1-chloro-3-(2-methoxyphenoxy)-2-Propanol; 1-chloro-3-(o-methoxyphenoxy)-2-Propanol (6CI,8CI); 1-Chloro-3-(2-methoxyphenoxy)-2-propanol; 1-Chloro-3-(o-methoxyphenoxy)-2-propanol; 2-Hydroxy-3-(2-methoxyphenoxy)propyl chloride; Ranolazine Impurity 7. Grade: > 98%. CAS No. 25772-81-0. Molecular formula: C10H13ClO3. Mole weight: 216.66.
2-[ (2-Methoxyphenoxy) methyl]oxirane
Ranolazine intermediate. Group: Biochemicals. Alternative Names: 1-(2,3-Epoxypropoxy)-2-methoxybenzene; 1, 2-Epoxy-3- (2-methoxyphenoxy) propane; 1, 2-Epoxy-3- (o-methoxyphenoxy) propane; Glycidyl 2-Methoxyphenyl Ether; 1-(2-Methoxyphenoxy)-2,3-epoxypropane; NSC 112256; NSC 133442. Grades: Highly Purified. CAS No. 2210-74-4. Pack Sizes: 1g. US Biological Life Sciences.
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2-[ (2-Methoxyphenoxy) methyl]oxirane-d3
Ranolazine intermediate. Group: Biochemicals. Alternative Names: 1,2-Epoxy-3-(2-methoxy-d3-phenoxy)propane. Grades: Highly Purified. CAS No. 1054624-90-6. Pack Sizes: 5mg. US Biological Life Sciences.
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2-[(2-Methoxyphenoxy)methyl]oxirane-[d3]
2-[(2-Methoxyphenoxy)methyl]oxirane-[d3] is an isotope form of 2-[(2-Methoxyphenoxy)methyl]oxirane. 1-(2,3-Epoxypropoxy)-2-methoxybenzene is one of Ranolazine intermediates. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Uses: Ranolazine intermediate. Synonyms: 1,2-Epoxy-3-(2-methoxy-d3-phenoxy)propane; 2-(2,3-Epoxypropoxy)anisole-d3; 2-Methoxy-d3-1-(oxiranylmethoxy)benzene; 2-Methoxyphenyl-d3 Glycidyl Ether; Glycidyl 2-Methoxyphenyl-d3 Ether. Grade: 95%. CAS No. 1054624-90-6. Molecular formula: C10H9D3O3. Mole weight: 183.22.
α-[(2-Methoxyphenoxy)methyl]-1-piperazineethanol is a Ranolazine metabolite, an anti-ischemic agent which modulates myocardial metabolism. Group: Biochemicals. Alternative Names: RS 88681 Dihydrochloride; α-[(2-methoxyphenoxy)methyl]-1-Piperazineethanol Hydrochloride (1:2). Grades: Highly Purified. CAS No. 1185293-30-4. Pack Sizes: 250mg. US Biological Life Sciences.
α,α'-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol is a metabolite of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. α,α'-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol is also known to exhibit anti-anginal activities. Group: Biochemicals. Alternative Names: α1,α4-Bis[(2-methoxyphenoxy)methyl]-1,4-piperazinediethanol. Grades: Highly Purified. CAS No. 333749-57-8. Pack Sizes: 250mg. US Biological Life Sciences.
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CVT-3369
CVT-3369 is an impurity of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: RS-91347; 4-[2-Hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetic Acid; Ranolazine Impurity 16; CVT 3369; CVT3369; RS 91347; RS91347; 1-Piperazineacetic acid, 4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-. Grade: 98%. CAS No. 172430-48-7. Molecular formula: C16H24N2O5. Mole weight: 324.37.
Guaiacol glycidyl ether
1-(2,3-Epoxypropoxy)-2-methoxybenzene is one of Ranolazine intermediates. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Synonyms: 1,2-Epoxy-3-(2-methoxyphenoxy)propane; 1,2-Epoxy-3-(o-methoxyphenoxy)propane; Glycidyl 2-Methoxyphenyl Ether; 1-(2-Methoxyphenoxy)-2,3-epoxypropane; NSC 112256; NSC 133442; Guaiacol glycidyl ether; Methoxyphenyl glycidyl ether; Ranolazine Impurity 6; Ranolazine USP Related Compound A. Grade: 96%. CAS No. 2210-74-4. Molecular formula: C10H12O3. Mole weight: 180.20.
An isotope labelled intermediate of Ranolazine. Ranolazine is a drug to treat angina. Synonyms: Ranolazine-D8 Impurity. Grade: 95% by HPLC; 98% atom D. Molecular formula: C24H24D8N4O2. Mole weight: 416.59.
N-(2,6-Dimethylphenyl)-1-piperazineacetamide
A metabolite of Ranolazine. Group: Biochemicals. Alternative Names: 1-Piperazineaceto-2',6'-xylidide; 4- [ (2, 6-Dimethylphenyl) aminocarbonylmethyl] piperazine; N-(2,6-Dimethylphenyl)-2-piperazinylacetamide; RS 94287. Grades: Highly Purified. CAS No. 5294-61-1. Pack Sizes: 1g. US Biological Life Sciences.
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N-(2,6-Dimethylphenyl)-1-piperazineacetamide-[d8]
N-(2,6-Dimethylphenyl)-1-piperazineacetamide-[d8] is the labelled analogue of N-(2,6-Dimethylphenyl)-1-piperazineacetamide, which is a metabolite of Ranolazine. Ranolazine is a drug used to treat angina pectoris. Synonyms: 1-Piperazineaceto-2',6'-xylidide-d8; 4-[(2,6-Dimethylphenyl)aminocarbonylmethyl]piperazine-d8; N-(2,6-Dimethylphenyl)-2-piperazinylacetamide-d8; RS 94287-d8. Grade: ≥95%. Molecular formula: C14H13D8N3O. Mole weight: 255.39.
N- (2, 6-Dimethylphenyl) -2-[4-[2-hydroxy-3- (2-methoxyphenoxy) propyl]piperazin-1-yl]acetamide. Group: Biochemicals. Alternative Names: Ranolazine; N- (2, 6-Dimethylphenyl) -2-[4-[2-hydroxy-3- (2-methoxyphenoxy) propyl]piperazin-1-yl]acetamide dihydrochloride; Ranolazine HCl. Grades: Highly Purified. CAS No. 95635-55-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C24H33N3O4. US Biological Life Sciences.
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N-(2,6-Diphenylmethyl)-1-piperazine acetylamine
N-(2,6-Dimethylphenyl)-1-piperazineacetamide is an impurity of Ranolazine. Ranolazine is a drug used to treat angina pectoris. Synonyms: CVT-2738; RS-94287; CVT2738; CVT 2738; 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-; 1-Piperazineaceto-2',6'-xylidide; N-(2,6-Dimethylphenyl)-1-piperazineacetamide; 4-[(2,6-Dimethylphenyl)aminocarbonylmethyl]piperazine; N-(2,6-Dimethylphenyl)-2-(1-piperazinyl)acetamide; N-(2,6-Dimethylphenyl)-2-piperazinylacetamide; RS 94287; RS94287. Grade: ≥95%. CAS No. 5294-61-1. Molecular formula: C14H21N3O. Mole weight: 247.34.
N,N'-bis(2,6-Dimethylphenyl)-1,4-piperazinediacetamide is an intermediate of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. Ranolazine is also known to exert antianginal activities. Group: Biochemicals. Alternative Names: N1,N4-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide. Grades: Highly Purified. CAS No. 380204-72-8. Pack Sizes: 250mg. US Biological Life Sciences.
(R)-1-(2-((2,6-Dimethylphenyl)amino)-2-oxoethyl)-4-(2-hydroxy-3-(2-methoxy-6-(trifluoromethyl)phenoxy)propyl)piperazin-1-ium is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C25H33F3N3O4?. Mole weight: 496.54.
(R)-2-(4-(2-Hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)-N-(o-tolyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C23H31N3O4. Mole weight: 413.51.
(R)-2-(4-(3-(2,6-Dimethoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C25H35N3O5. Mole weight: 457.56.
(R)-2-(4-(3-(2-Chloro-6-methoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H32ClN3O4. Mole weight: 461.98.
(R)-2-(4-(3-(2-(tert-Butoxy)phenoxy)-2-hydroxypropyl)piperazin-1-yl)-N-(2,6-dimethoxyphenyl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C27H39N3O6. Mole weight: 501.61.
(R)-N-(2,6-Dimethoxyphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenethoxy)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C26H37N3O6. Mole weight: 487.59.
(R)-N-(2,6-Dimethoxyphenyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H33N3O6. Mole weight: 459.53.
(R)-N-(2,6-Dimethylbenzyl)-2-(4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C25H35N3O4. Mole weight: 441.56.
(R)-N-(2,6-Dimethylphenyl)-2-(4-(3-(2-fluoro-6-methoxyphenoxy)-2-hydroxypropyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H32FN3O4. Mole weight: 445.53.
(S)-N-(2,6-Dimethylphenyl)-2-(4-(2-hydroxy-3-((2-methoxyphenyl)amino)propyl)piperazin-1-yl)acetamide is one of Ranolazine impurities. Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Molecular formula: C24H34N4O3. Mole weight: 426.55.
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