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| Product | Description | |
|---|---|---|
| RNA Polymerase II, C-terminal domain, GST tagged human | recombinant, expressed in E. coli, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| RNA Polymerase II, C-terminal human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase III Inhibitor - CAS 577784-91-9 | RNA Polymerase III Inhibitor, CAS 577784-91-9, is a cell-permeable inhibitor of RNA Polymerase III (IC?? = 27 and 32 μM for human and S. cerevisiae RNA Pol III, respectively). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p14.5 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p14.5 subunit human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p15.6 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p33 subunit, GST tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p33 subunit human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, RPB10 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, RPB12 subunit, GST tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, RPB8 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| DNA-directed RNA polymerase | Catalyses DNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to α-amanitin, and the type of RNA synthesized. See also EC 2.7.7.19 (polynucleotide adenylyltransferase) and EC 2.7.7.48 (RNA-directed RNA polymerase). Group: Enzymes. Synonyms: RNA polymerase; RNA nucleotidyltransferas. Enzyme Commission Number: EC 2.7.7.6. CAS No. 9014-24-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3271; DNA-directed RNA polymerase; EC 2.7.7.6; 9014-24-8; RNA polymerase; RNA nucleotidyltransferase (DNA-directed); RNA polymerase I; RNA polymerase II; RNA polymerase III; C RNA formation factors; deoxyribonucleic acid-dependent ribonucleic acid polymerase; DNA-dependent ribonucleate nucleotidyltransferase; DNA-dependent RNA nucleotidyltransferase; DNA-dependent RNA polymerase; ribonucleate nucleotidyltransferase; ribonucleate polymerase; C ribonucleic acid formation factors; ribonucleic acid nucleotidyltransferase; ribonucleic acid polymerase; ribonucleic acid transcriptase; ribonucleic polymerase; ribonucleic transcriptase; RNA nucleotidyltransferase; RNA transcriptase; transcriptase; RNA nucleotidyltransferase I. |  |
| InSolution RNA Polymerase III Inhibitor - CAS 577784-91-9 | The RNA Polymerase III Inhibitor, also referenced under CAS 577784-91-9, controls the biological activity of RNA Polymerase III. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| Modified T7 RNA polymerase | A modified T7 RNA polymerase that orthogonally recognizes a non-natural promoter sequence: 5-TAATACCGGTCACTATA, where the underlined residues differ from wild-type. Group: Enzymes. Synonyms: CGG-R12-KIR. Enzyme Commission Number: EC 2.7.7.6. CAS No. 9014-24-8. Purity: > 98% (SDS-PAGE). Mole weight: 100.142 kDa. Storage: at -20 °C. Form: Liquid. CGG-R12-KIR; Non-Natural Promoter T7 Polymerase; modified T7 RNA polymerase; T7 RNA polymerase. Cat No: NATE-1698. | |
| Native E. coli RNA Polymerase, Holoenzyme | E. coli RNA Polymerase, Holoenzyme is the core enzyme saturated with sigma factor 70. The Holoenzyme initiates RNA synthesis from sigma 70 specific bacterial and phage promoters. E. coli RNA Polymerase, Core Enzyme consists of 5 subunits designated α, α, β?, β, and &omega. The enzyme is free of sigma factor and does not recognize any specific bacterial or phage DNA promoters. The enzyme retains the ability to transcribe RNA from nonspecific initiation sequences. Addition of sigma factors will allow the enzyme to initiate RNA synthesis from specific bacterial and phage promoters. Applications: Rna synthesis from e. coli promoter transcription initiation studies in vitro translation with purexpress. Group: Enzymes. Synonyms: E. coli RNA Polymerase, Holoenzyme; E. coli RNA Polymerase; RNA Polymerase; RNAP; RNApol; DNA-dependent RNA polymerase. RNAP. Mole weight: 400 kDa. Storage: at -20°C. Form: 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 0.1 mM EDTA, 1 mM dithiothreitol (DTT) and 50% glycerol. Source: E. coli. E. coli RNA Polymerase, Holoenzyme; E. coli RNA Polymerase; RNA Polymerase; RNAP; RNApol; DNA-dependent RNA polymerase. Cat No: NATE-1262. | |
| RNA-directed DNA polymerase | Catalyses RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo. Requires an RNA or DNA primer. DNA can also serve as template. See also EC 2.7.7.7 DNA-directed DNA polymerase. Group: Enzymes. Synonyms: DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Enzyme Commission Number: EC 2.7.7.49. CAS No. 9068-38-6. RT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3261; RNA-directed DNA polymerase; EC 2.7.7.49; 9068-38-6; DNA nucleotidyltransferase (RNA-directed); reverse transcriptase; revertase; RNA-dependent deoxyribonucleate nucleotidyltransferase; RNA revertase; RNA-dependent DNA polymerase; RNA-instructed DNA polymerase; RT. Cat No: EXWM-3261. | |
| RNA-directed RNA polymerase | Catalyses RNA-template-directed extension of the 3'- end of an RNA strand by one nucleotide at a time. Can initiate a chain de novo. See also EC 2.7.7.6 DNA-directed RNA polymerase. Group: Enzymes. Synonyms: RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonuclei. Enzyme Commission Number: EC 2.7.7.48. CAS No. 9026-28-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3260; RNA-directed RNA polymerase; EC 2.7.7.48; 9026-28-2; RNA nucleotidyltransferase (RNA-directed); RNA nucleotidyltransferase (RNA-directed); RNA-dependent ribonucleate nucleotidyltransferase; 3D polymerase; PB1 proteins; PB2 proteins; phage f2 replicase; polymerase L; Q-β replicase; phage f2 replicase; ribonucleic acid replicase; ribonucleic acid-dependent ribonucleate nucleotidyltransferase; ribonucleic acid-dependent ribonucleic acid polymerase; ribonucleic replicase; ribonucleic synthetase; RNA replicase; RNA synthetase; RNA transcriptase; RNA-dependent ribonucleate nucleotidyltransferase; RDRP; RNA-dependent RNA polymerase; RNA-dependent RNA replicase; transcriptase. Cat No: EXWM-3260. | |
| [RNA-polymerase]-subunit kinase | The enzyme appears to be distinct from other protein kinases. It brings about multiple phosphorylations of the unique C-terminal repeat domain of the largest subunit of eukaryotic DNA-directed RNA polymerase (EC 2.7.7.6). The enzyme does not phosphorylate casein, phosvitin or histone. Group: Enzymes. Synonyms: CTD kinase; STK9. Enzyme Commission Number: EC 2.7.11.23. CAS No. 122097-00-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3143; [RNA-polymerase]-subunit kinase; EC 2.7.11.23; 122097-00-1; CTD kinase; STK9. Cat No: EXWM-3143. | |
| T7 RNA polymerase | T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+ , T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9014-24-8. Pack Sizes: 1 KU; 5 KU. Product ID: HY-E70090. |  |
| 1-(2'-O-Acetyl-3',5'-bis-O-benzoyl-b-D-xylofuranosyl)-6-azauracil | 1-(2'-O-Acetyl-3',5'-bis-O-benzoyl-b-D-xylofuranosyl)-6-azauracil, a synthetic compound with antiviral and anticancer properties, offers a unique opportunity for biomedical research. It targets RNA replication in viruses and cancers, including hepatitis C virus and certain types of leukemia. With its potent inhibition of RNA polymerase, this product presents a promising avenue towards developing effective treatments for these diseases. Exploring the therapeutic potential of this compound could open up new doors for the field of medicine. Synonyms: 2'-O-Acetyl-3',5'-bis-O-benzoyl-6-aza-xylouridine; (2R,3S,4R,5R)-4-Acetoxy-2-((benzoyloxy)methyl)-5-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)tetrahydrofuran-3-yl benzoate; 2-(2-O-Acetyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione. Grades: ≥95%. CAS No. 161615-21-0. Molecular formula: C24H21N3O9. Mole weight: 495.44. |  |
| 1-Benzylindole-3-carbaldehyde | 1-Benzylindole-3-carbaldehyde was patented as an oncogenic ras-specific cytotoxic Oncrasin compund for treatment of cancer and viral infections. It was also studied to show its inhibitory effect on RNA polymerase II as a potential anticancer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 10511-51-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H13NO, Molecular Weight: 235.28. US Biological Life Sciences. |  Worldwide |
| 1-Butyl-3-(1,1-dioxido-2H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinone | Heterocyclic inhibitor of the RNA-dependent RNA polymerase enzyme transcribed by the Hepatitis C virus. Group: Biochemicals. Grades: Highly Purified. CAS No. 303776-83-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1'-epi-PSI-6130 | As an epimer of PSI-6130, 1'-epi-PSI-6130 is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Molecular formula: C10H14FN3O4. Mole weight: 259.23. | |
| 1-epi-PSI-6130 | 1-epi-PSI-6130 is an epimer of PSI-6130 (P839680) which is an experimental treatment for hepatitis C. PSI-6130 is a member of a class of antiviral drugs known as nucleoside polymerase inhibitors. PSI-6130 inhibits the hepatitis C virus RNA dependant RNA polymerase called NS5B. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H14FN3O4, Molecular Weight: 259.23. US Biological Life Sciences. | Worldwide |
| 2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine | 2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouridine, a highly effective antiviral compound, demonstrates remarkable capabilities in combating viral infections. By impeding viral RNA replication and selectively targeting the viral polymerase, it exhibits an extensive range of activity against diverse viruses such as influenza and herpesvirus. Synonyms: 2',3',5'-Tri-O-benzoyl-2'-β-C-methyl-5-fluorouridine. Grades: ≥95%. CAS No. 2072145-49-2. Molecular formula: C31H25FN2O9. Mole weight: 588.54. | |
| 2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyluridine | 2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyluridine is a highly modified nucleoside characterized by its frequent use in RNA synthesis. Acting as a substrate for RNA polymerases, its presence ensures the efficient addition of other nucleotides, ultimately leading to the formation of RNA target sequences. This unique compound also has the added benefit of offering insight into the effects of nucleoside modifications on RNA's biological structure and function. Synonyms: 2',3',5'-Tris-O-[(1,1-dimethylethyl)dimethylsilyl]-4'-C-(hydroxymethyl)-Uridine; 1-{2,3-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]-4-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-α-L-lyxofuranosyl}-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 232588-97-5. Molecular formula: C28H56N2O7Si3. Mole weight: 617.01. | |
| 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) | 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a biomedically significant reagent used to investigate the intricate mechanisms of DNA synthesis and repair. As a non-hydrolyzable analog of adenosine triphosphate (ATP), it is implicated in inhibiting the activity of reverse transcriptase - a vital aspect of HIV/AIDS treatment. With its remarkable affinity and specificity towards RNA polymerase and other enzymes central to DNA metabolism, this powerful tool is a prized asset for researchers in the biomedical field. Synonyms: Alpha Thiol ddATP; 1-Thio-ddATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O10P3S. Mole weight: 491.20. | |
| 2',3'-Dideoxyadenosine-5'-Triphosphate | 2',3'-Dideoxyadenosine-5'-Triphosphate is a nucleoside triphosphate analogue commonly used in biomedical research to study polymerases and reverse transcriptases. It can be incorporated into DNA or RNA strands, resulting in chain termination and inhibition of replication. Additionally, 2',3'-Dideoxyadenosine-5'-Triphosphate has potential antiviral properties and has been studied as a treatment for HIV and hepatitis B. Synonyms: ddATP. Grades: ≥95% by AX-HPLC. Molecular formula: C10H16N5O11P3. Mole weight: 475.10. | |
| 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate) | 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate), a potent nucleotide analog, serves as a promising biomedical product towards combatting multiple viral infections such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV). Not only does this chain-terminating inhibitor effectively target viral reverse transcriptase and RNA polymerase, but it also displays promising results in cancer treatment and cell signaling research. Its potential to revolutionize antiviral therapy warrants further exploration. Synonyms: Alpha Thiol ddGTP; 1-Thio-ddGTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H16N5O11P3S. Mole weight: 507.25. | |
| 2',3'-Dideoxyinosine-5'-Triphosphate | 2',3'-Dideoxyinosine-5'-Triphosphate, a nucleoside analogue predominantly employed for investigating facets of DNA and RNA replication, impeding reverse transcriptases, and regulating DNA polymerases, exhibits immense potential as an efficient therapeutic agent against a host of viral infections, such as HIV. Synonyms: ddITP; Didanosine triphosphate. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N4O12P3. Mole weight: 476.10. | |
| 2',3'-Di-O-isopropylidene-5-hydroxymethyluridine | 2',3'-Di-O-isopropylidene-5-hydroxymethyluridine, a nucleoside analogue, has been widely utilized in biomedical research as a vital and consequential substrate for RNA polymerase. The paramountcy of this analog has been accentuated by its incumbent placement in oligonucleotides wherein its impact on RNA structure and function has been meticulously studied. The prospects of this compound have been extolled as it has been observed to proffer inhibitory effects on select viral strains, thereby enhancing its application in the treatment of viral diseases. Synonyms: 5-(hydroxymethyl)-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O,3'-O-Isopropylidene-5-(hydroxymethyl)uridine; 2',3'-O-Isopropylidene-5-hydroxymethyluridine; 5-Hydroxymethyl-2',3'-(di-O-isopropylidene)uridine; 5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)uridine; 5-(Hydroxymethyl)-2',3'-O-isopropylideneuridine. Grades: ≥95%. CAS No. 3816-77-1. Molecular formula: C13H18N2O7. Mole weight: 314.29. | |
| 2,3-Isopropylidene ribavirin | 2,3-Isopropylidene ribavirin, an exceedingly potent antiviral agent, serves as a crucial therapeutic solution for the management of hepatitis C virus (HCV) infection. With its robust inhibitory prowess exhibited against HCV RNA-dependent RNA polymerase, it remarkably curtails viral replication. Synonyms: 1-[2,3-O-(1-Methylethylidene)-b-D-ribofuranosyl]-1H-1,2,4-triazole-3-carboxamide. CAS No. 52663-90-8. Molecular formula: C11H16N4O5. Mole weight: 284.27. | |
| 2,3-O-Isopropylidene-1,5-di-O-toluoyl-b-D-ribofuranose | 2,3-O-Isopropylidene-1,5-di-O-toluoyl-b-D-ribofuranose, a multifaceted compound, holds immense significance in the field of biomedical research. Its primary usage lies in the synthesis of antiviral medications aimed at RNA-dependent RNA polymerases. Moreover, this compound serves as a valuable tool in the investigation of metabolic disorders, such as diabetes, facilitating an in-depth analysis of glucose metabolism and glycemic control. Synonyms: 1,5-Di-O-toluoyl-2,3-O-isopropylidene-b-D-ribofuranose. CAS No. 86042-28-6. Molecular formula: C24H26NO7. Mole weight: 440.47. | |
| 2,4,6-triisopropylbenzenesulfonyl azide | 2,4,6-Triisopropylbenzenesulfonyl Azide is a useful synthetic intermediate. It is used in the synthesis of Antidote to anthrax lethal factor intoxication, bacterial RNA polymerase inhibitors and bicyclic extended dipeptide surrogates. Synonyms: TPS-N3; Trisyl azide; 2,4,6-Triisopropylphenylsulfonyl azide; 2,4,6-Tris(1-methylethyl)-benzenesulfonyl azide; ACMC-1CT2Q; N-diazo-2,4,6-triisopropyl-benzenesulfonamide; NSC 646156. Grades: 98 %. CAS No. 36982-84-0. Molecular formula: C15H23N3O2S. Mole weight: 309.43. | |
| 2-(4-Bromo-2-fluorophenyl)-2-methylpropanenitrile | 2-(4-Bromo-2-fluorophenyl)-2-methylpropanenitrile is used in the discovery of dihydropyrone series as HCV RNA-dependent RNA polymerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 749928-77-6. Pack Sizes: 100mg, 500mg. Molecular Formula: C10H9BrFN, Molecular Weight: 242.09. US Biological Life Sciences. | Worldwide |
| 2,5'-Anhydro-2'-deoxyuridine | 2,5'-Anhydro-2'-deoxyuridine is a specialized biomolecular compound primarily used in the research of viral diseases. Its inhibitory effect on viral RNA or DNA polymerase makes it a vital component in medications fighting Hepatitis B and HIV. Synonyms: (6R,8S,9R)-8-Hydroxy-7,8,9,10-tetrahydro-6,9-epoxypyrimido[2,1-b][1,3]oxazocin-2(6H)-one; 2,5'-Anhydro-1-(2-deoxy-beta-D-erythro-pentofuranosyl)uracil; 6,9-Epoxy-2H,6H-pyrimido[2,1-b][1,3]oxazocin-2-one, 7,8,9,10-tetrahydro-8-hydroxy-, (6R,8S,9R)-. Grades: ≥95%. CAS No. 20701-12-6. Molecular formula: C9H10N2O4. Mole weight: 210.19. | |
| 2,5-Di-O-benzyl-3-deoxy-3-fluoro-b-D-ribofuranose | 2,5-Di-O-benzyl-3-deoxy-3-fluoro-b-D-ribofuranose is a structurally modified synthetic derivative that has gained considerable attention as a prospective antiviral agent. Its potential usage as a therapeutic agent in the treatment of contemporarily prevalent RNA viruses such as HCV and SARS-CoV make it a significant molecule with undeniable biomedical significance. Specifically, this compound has been investigated as a nucleoside analogue for its ability to inhibit viral RNA replication through impeding the virus's RNA-dependent RNA polymerase. CAS No. 123369-31-3. Molecular formula: C19H21FO4. Mole weight: 332.4. | |
| 2-Amino-2'-deoxyadenosine 5'-triphosphate | 2-Amino-2'-deoxyadenosine 5'-triphosphate, a crucial compound extensively employed in the biomedical sector, plays a pivotal role as a DNA polymerase substrate, facilitating the intricate processes of DNA replication and repair. Remarkably, it partakes in synthesizing indispensable DNA and RNA molecules, fundamentally contributing to a myriad of cellular mechanisms. Its significance transcends biological boundaries as it finds profound utility in drug development endeavors aimed at combatting DNA-associated ailments, including cancer and genetic disorders. Synonyms: [[(2R,3S,5R)-5-(2,6-diaminopurin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Ddaptp; (((2R,3S,5R)-5-(2,6-Diamino-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid; 2-NH2-Datp; 2-Amino-2'-deoxyadenosine 5'-triphosphate; 2-amino-2' deoxyadenosine 5'-triphosphate; 2,6-Diaminopurine deoxyribonucleoside triphosphate; Boc-(R)-3-Amino-3-(3-nitro-phenyl)-propionicacid; Adenosine 5'-(tetrahydrogen triphosphate), 2-amino-2'-deoxy-; 9-[2-Deoxy-5-O- (hydroxy{[hydroxy (phosphonooxy) phosphoryl]oxy}phosphoryl) pentofuranosyl]-2-imino-2, 9-dihydro-1H-purin-6-amine. CAS No. 81503-63-1. Molecular formula: C10H17N6O12P3. Mole weight: 506.20. | |
| 2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine | 2-Amino-2'-deoxy-N6,N6-dimethyl-2'-adenosine is an intriguing biomedical agent, conquering the realm of antiviral mastery and enveloping RNA pathogens within its strategic web. Through an artful act of termination, this compound disrupts viral replication. Such fortitude emanates from its prowess in inhibiting viral polymerase activity, thwarting the insidious dance of their replication and gallantly diminishing the burden of viral load. Synonyms: 6-Dma-dguo; 6-Dimethylamino-2'-deoxyguanosine; Adenosine, 2-amino-2'-deoxy-N,N-dimethyl-; 2'-Deoxy-6-dimethylaminoguanosine; 2-Amino-6-(dimethylamino)-9-(2-deoxy-beta-D-ribofuranosyl)-9H-purine; 9-(2-Deoxypentofuranosyl)-2-imino-N,N-dimethyl-2,9-dihydro-1H-purin-6-amine. Grades: ≥95%. CAS No. 83061-20-5. Molecular formula: C12H18N6O3. Mole weight: 294.31. | |
| 2-Amino-6-chloropurineriboside-5'-Triphosphate | 2-Amino-6-chloropurineriboside-5'-Triphosphate has garnered significant attention as a potent nucleotide analog, penetrating the intricate DNA and RNA polymerases upon interaction. Found commonly in DNA replication and repair mechanisms, its versatility as a molecular tool extends towards illuminating disease patterns mechanized by DNA damage, including the enigmatic realm of viral infections and cancers. Synonyms: 2-Amino-6-Cl-purine-rTP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H15N5O13P3Cl. Mole weight: 541.62. | |
| 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine | 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine, a powerful antiviral drug, has proven effective in controlling hepatitis C viral infections. Its potent mechanism of action involves binding to and inhibiting the viral RNA polymerase, thereby reducing viral replication, viral load and disease progression. Not content with tackling hepatitis C alone, this remarkable compound has also been investigated for its potential use against HIV, influenza and even select cancers like chronic lymphocytic leukemia. Its versatility and unique mechanism of action make 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine a valuable addition to any clinician's armamentarium in the battle against viral infections and other diseases. Synonyms: 2-Amino-N6,N6-dimethyl-2'-deoxy-2'-fluoro-β-D-arabino-adenosine; (2R,3R,4S,5R)-5-[2-amino-6-(dimethylamino)purin-9-yl]-4-fluoro-2-(hydroxymethyl)oxolan-3-ol. Grades: ≥95%. CAS No. 2171103-80-1. Molecular formula: C12H17FN6O3. Mole weight: 312.30. | |
| 2'-Azido-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine | 2'-Azido-N4-benzoyl-2',3'-dideoxy-5'-O-DMT-cytidine is an exceedingly potent antiviral compound, emerging as an exalted tool in research against dread viral afflictions. Most notably efficacious against pernicious RNA-dependent DNA polymerase-dependent viruses encompassing indomitable HIV and formidable hepatitis B, this compound ventures to ensnare and subvert the bustling viral reverse transcriptase, thus impeding the pernicious replication and dissemination of viral entities within the corporeal domain. CAS No. 170236-33-6. Molecular formula: C37H34N6O6. Mole weight: 658.70. | |
| 2'-C-Methylcytidine | A nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks viral production of HCV RNA and thus viral replication. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidin-2-one; 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one; 2'-C-methylcytidine; valopicitabine; Cytidine,2'-C-methyl. Grades: ≥ 95%. CAS No. 20724-73-6. Molecular formula: C10H15N3O5. Mole weight: 257.24. | |
| 2'-Deoxy-2',2'-difluoro-b-D-ribofuranose | 2'-Deoxy-2',2'-difluoro-b-D-ribofuranose, a critical molecule extensively applied in the biomedical field, possesses profound implications. This prominent compound assumes a pivotal position in the fabrication of antiviral medications, especially those that aim at RNA-dependent RNA polymerase. Furthermore, it assumes an indispensable function in the formulation of remedies for viral afflictions encompassing hepatitis C, influenza, and HIV/AIDS. CAS No. 252932-95-9. Molecular formula: C5H8F2O4. Mole weight: 170.11. | |
| 2'-Deoxy-2',2'-difluoroguanosine | 2'-Deoxy-2',2'-difluoroguanosine is a potent antiviral drug commonly used to inhibit the replication of RNA viruses, such as Dengue or West Nile virus. It acts as a nucleotide analog, interfering with viral RNA synthesis through inhibiting the viral RNA polymerase. Synonyms: 2',2'-Difluorodeoxyguanosine. Grades: 95%. CAS No. 103882-87-7. Molecular formula: C10H11F2N5O4. Mole weight: 303.22. | |
| 2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine | 2'-Deoxy-2'-fluoro-2-methoxy-b-D-arabinoadenosine is a potent antiviral compound, exerting its effects by selectively impeding the replication of viral RNA through the inhibition of its RNA-dependent RNA polymerase. Synonyms: 2-Methoxy-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine; (2R,3R,4S,5R)-5-(6-Amino-2-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-2-methoxy-9H-purin-6-amine. Grades: ≥95%. CAS No. 1093278-52-4. Molecular formula: C11H14FN5O4. Mole weight: 299.26. | |
| 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine | 2'-Deoxy-2'-fluoro-4-deoxy-arabinouridine is a nucleoside analog used as an antiviral drug against hepatitis B virus (HBV) and hepatitis C virus (HCV). It inhibits viral polymerase activity and causes chain termination during viral genome replication, thus reducing viral load in infected individuals. This product has potential as a therapeutic agent against other RNA viruses such as Ebola and Zika. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinoribofuanosyl)-2(1H)-pyrimidinone; 1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-Arafluorozebularine; 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)pyrimidin-2-(1H)-one. Grades: ≥95%. CAS No. 136675-88-2. Molecular formula: C9H11FN2O4. Mole weight: 230.19. | |
| 2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine | 2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine is an exceptional antiviral compound, exhibiting remarkable potential in the research of biomedicine for tackling viral afflictions. Its robustness lies in its ability to suppress viral replication through the selective inhibition of viral polymerase activity, impeding viral RNA synthesis. Uses: Enzyme inhibitors. Synonyms: 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; FF-Ara-ura; 5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-fluorouracil. Grades: ≥95%. CAS No. 69123-95-1. Molecular formula: C9H10F2N2O5. Mole weight: 264.18. | |
| 2'-Deoxy-2'-fluoro-5-methylcytidine | 2'-Deoxy-2'-fluoro-5-methylcytidine is a potent antiviral compound used in the reserch of various viral diseases. It exhibiting significant activity against influenza A and B viruses, including oseltamivir-resistant strains. This nucleoside analogue interferes with viral replication by inhibiting RNA synthesis and polymerase activity. Synonyms: 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-5-methyl-; 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 182495-80-3. Molecular formula: C10H14FN3O4. Mole weight: 259.23. | |
| 2'-Deoxy-2'-fluoro-L-uridine | 2'-Deoxy-2'-fluoro-l-uridine is an L-nucleoside compound. 2'-Deoxy-2'-fluoro-l-uridine is a potent, selective viral RNA polymerase inhibitor, thereby inhibiting RNA virus replication. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (S)-2-chloro-butyric acid dimethylamide; L-2-Chlor-N,N-dimethyl-butyramid; L-2-deoxy-2-fluorouridine; (S)-2-Chlor-buttersaeure-dimethylamid; 2-Chloro-N,N-dimethylbutyramide; Butanamide,2-chloro-N,N-dimethyl; 2-fluoro-L-uridine. Product Category: Inhibitors. Appearance: White to off-white solid. CAS No. 622785-69-7. Molecular formula: C9H11FN2O5. Mole weight: 246.2. Purity: 0.96. IUPACName: 1-[(2R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Canonical SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F. Product ID: ACM622785697. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2'-Deoxy-2'-fluorouridine. |  |
| 2'-Deoxy-2'-fluoro-N1-methyluridine | 2'-Deoxy-2'-fluoro-N1-methyluridine, a potent compound in biomedicine, assumes a pivotal role in curbing viral infections of RNA origin. This nucleoside analog acts as a formidable antagonist against viral replication, directing its efforts principally towards the viral polymerase enzyme. It has been shown to be effective against a wide range of RNA viruses, including influenza, hepatitis C, and respiratory syncytial virus (RSV). Synonyms: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methylpyrimidine-2,4-dione. Grades: ≥95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| 2'-Deoxy-2'-fluoro-N3-[(pyridin-2-yl)methyl]-beta-D-arabinouridine | 2'-Deoxy-2'-fluoro-N3-[(pyridin-2-yl)methyl]-beta-D-arabinouridine, a highly sophisticated antiviral agent , exhibits immense proficiency in combating specific viral infections. Employing a meticulous approach, it precisely intervenes with the replication mechanism of the virus, effectively obstructing the viral polymerase enzyme and impeding the synthesis of viral RNA. Remarkably, this pharmaceutical marvel has been proven efficacious in battling diverse viral ailments including hepatitis C and respiratory syncytial virus (RSV) infections. Synonyms: 2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]-β-D-arabinouridine. Grades: ≥95%. CAS No. 2072145-51-6. Molecular formula: C15H16FN3O5. Mole weight: 337.30. | |
| 2'-Deoxy-2'-fluoro-N3-[(pyridin-4-yl)methyl]-beta-D-arabinouridine | 2'-Deoxy-2'-fluoro-N3-[(pyridin-4-yl)methyl]-beta-D-arabinouridine is a highly effective antiviral compound widely used in the biomedical field as a powerful therapeutic intervention against RNA viruses. By selectively modulating viral RNA polymerase, it rapidly inhibits viral replication and effectively prevents viral proliferation and transmission. Synonyms: 2'-Deoxy-2'-fluoro-N3-[(pyrid-4-yl)methyl]-β-D-arabinouridine. Grades: ≥95%. CAS No. 2072145-47-0. Molecular formula: C15H16FN3O5. Mole weight: 337.30. | |
| 2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt | 2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt is a vital component in the biomedicine field. It is commonly used in molecular biology research and drug development. This compound serves as a substrate for reverse transcriptases and DNA polymerases, playing a crucial role in the synthesis of various modified nucleic acids. It is particularly utilized in the study of RNA function and structure and the development of antiviral drugs targeting RNA viruses. Synonyms: 2'F-dUTP.Na. Grades: 95%. Molecular formula: C9H14FN2O14P3·Na. Mole weight: 509.12 (free acid). | |
| 2'-Deoxy-5-methyl-isocytidine triphosphate | 2'-Deoxy-5-methyl-isocytidine triphosphate, a paramount substance in the realm of biomedical research, serves as an indispensable component for synthesizing intricate DNA and RNA molecules. Its significance lies in its role as a substrate for DNA polymerases, thereby assuming a pivotal position in an array of molecular biology methodologies encompassing PCR, DNA sequencing, and mutagenesis investigations. Synonyms: 4(1H)-Pyrimidinone, 2-amino-1-[2-deoxy-5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-erythro-pentofuranosyl]-5-methyl-; 2-Amino-1-[2-deoxy-5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-erythro-pentofuranosyl]-5-methyl-4 (1H) -pyrimidinone; ((2R,3S,5R)-5-(2-amino-5-methyl-4-oxopyrimidin-1(4H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 2'-Deoxy-5-methylisocytidine 5'-triphosphoric acid. CAS No. 139157-80-5. Molecular formula: C10H18N3O13P3. Mole weight: 481.18. | |
| 2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine | 2'-Deoxy-5'-O-DMT-2'-fluoro-L-uridine, an intriguing nucleoside analog, has undergone scrutiny for its antiviral activity against hepatitis C virus. Excitingly, not only has it shown potential as an antiviral therapy, but it has also been efficacious against certain variants of cancer, such as colon cancer and leukemia. How does it manage to be such a promising candidate? By inhibiting the viral NS5B polymerase, this compound disrupts viral RNA replication. Such a revolutionary advancement may prove crucial in future antiviral therapies. Molecular formula: C30H29FN2O7. Mole weight: 548.57. | |
| 2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt | 2'-Deoxyadenosine 5'-a-thiotriphosphate sodium salt is a crucial tool extensively used in the biomedical industry for various research purposes. It serves as a modified nucleotide analog used in DNA sequencing, structural analyses, and enzyme kinetics studies. Additionally, it finds utility in developing antiviral drugs targeting specific viral RNA or DNA polymerases. Molecular formula: C10H12N5Na3O12P3S. Mole weight: 588.18. | |
| 2'-Deoxycytidine-5'-O-(1-Thiotriphosphate) | 2'-Deoxycytidine-5'-O-(1-Thiotriphosphate) - a prime asset within the domain of pharmaceutical research. This compound is amply exploited in enzymatic assays, aimed at comprehending the intricacies of DNA-dependent RNA and DNA polymerases during both replication and transcription. Its merit notably extends towards the development of antiviral medications targeted at ameliorating the progression of viral infections inclusive of HIV. Synonyms: Alpha Thiol dCTP; 1-Thio-dCTP; alpha-Phosphorothioate-modified dctp. Grades: ≥95% by AX-HPLC. Molecular formula: C9H16N3O12P3S. Mole weight: 483.23. | |
| 2'-Deoxyguanylyl-(3'-5')-2'-deoxycytidine | 2'-Deoxyguanylyl-(3'-5')-2'-deoxycytidine, a nucleotide analog, serves as an efficacious treatment for an array of viral infections with proven antiviral activities against RNA viruses, including hepatitis C and coronavirus. It is known to operate through mimicking natural nucleotides crucial for viral RNA synthesis, thereby obstructing viral replication. Highly potent, it acts as an excellent inhibitor of viral RNA-dependent RNA polymerases, making it a formidable weapon against some of the most debilitating viral diseases. Synonyms: dGpdC DNA Dinucleotide (5'-3'); d(Gpc). Grades: ≥95% by AX-HPLC. CAS No. 23405-83-6. Molecular formula: C19H25N8O10P. Mole weight: 556.40. | |
| 2'-Deoxy-N4,N4,5-trimethylcytidine | 2'-Deoxy-N4,N4,5-trimethylcytidine is an exceedingly efficacious antiviral compound selectively antagonizing viral RNA polymerase, consequently impeding viral replication and abating the viral burden. Synonyms: 1-(2-Deoxypentofuranosyl)-4-(dimethylamino)-5-methylpyrimidin-2(1H)-one; 2'-Deoxy-N,N,5-trimethylcytidine; 2'-Deoxy-5,N4,N4-trimethylcytidine; 4-Dimethylaminothymidine; 4-Dma-TH; N,N,5-Trimethyl-2'-deoxycytidine. Grades: ≥95%. CAS No. 25406-45-5. Molecular formula: C12H19N3O4. Mole weight: 269.30. | |
| 2'-Fluoro-2'-deoxy-N6-methylarabinoadenosine | 2'-Fluoro-2'-deoxy-N6-methylarabinoadenosine is an intriguing nucleoside analog extensively employed in the realm of compound due to its exceptional antiviral attributes. With a unique mechanism of action, it selectively obstructs viral RNA research and development by meticulously honing in on viral polymerases. Synonyms: N6-methyl-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine; (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolan-3-ol; 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-N-methyl-9H-purin-6-amine. Grades: ≥95%. CAS No. 126502-12-3. Molecular formula: C11H14FN5O3. Mole weight: 283.26. | |
| 2'-Fluoro-ara-dUTP | 2'-Fluoro-ara-dUTP, a nucleotide analogue, is utilized as a substrate for DNA polymerases in molecular biology applications, its incorporation into DNA during replication results in chain termination and inhibition of DNA synthesis. Its antiviral and anticancer properties have been widely researched, attributed to its ability to inhibit the replication of viral DNA and RNA, as well as inducing apoptosis in cancer cells, making it a vital tool in the battle against these diseases. Synonyms: (2'F-ara-dUTP); 2'-Fluoro-2'-deoxy-ara-uridine-5'-triphosphate, Tetralithium salt; 2'-Fluoro-2'-deoxy-arabinofuranosyl-uracil-5'-triphosphate; 2'-F-ara-2'-dUTP. Grades: ≥ 95% by HPLC. Molecular formula: C9H14FN2O14P3 (free acid). Mole weight: 486.13 (free acid). | |
| 2-Furoylglycine | 2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolyl azabicyclooctyl ethyl piperidines as Ccr5 antagonists for the treatment of HIV infection. Group: Biochemicals. Grades: Highly Purified. CAS No. 5657-19-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C7H7NO4. US Biological Life Sciences. | Worldwide |
| 2-Furoylglycine-d3 | 2-Furoylglycine-d3 is the isotope labelled analog of 2-Furoylglycine (F865225); an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolyl azabicyclooctyl ethyl piperidines as Ccr5 antagonists for the treatment of HIV infection. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C7H4D3NO4. US Biological Life Sciences. | Worldwide |
| 2'-Mant-3'-dATP | 2'-Mant-3'-dATP serves as a fluorescent nucleotide analogue used in biomedical research for biochemical and structural applications, such as studying the dynamics and interactions of DNA and RNA polymerases, as well as DNA repair enzymes. Synonyms: 2'-O-(N-Methyl-anthraniloyl)-3'-deoxyadenosine-5'-triphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 313378-46-0. Molecular formula: C18H23N6O13P3 (free acid). Mole weight: 624.33 (free acid). | |
| 2'-O,4'-C-Methyleneguanosine | 2'-O,4'-C-Methyleneguanosine, a modified nucleoside molecule, has demonstrated effective outcomes in the domain of antiviral therapeutics, exemplifying excellent potential as a therapeutic agent for hepatitis C and West Nile virus infections. Substantiated by its unique mechanism of action- hindering viral RNA polymerase, a critical enzyme necessary for viral replication, it is deemed a highly potent approach for viral inhibition. Furthermore, this particular compound presents an enticing opportunity for its application as an antitumor agent, drawing interest from scientific communities. Synonyms: LNA-G; 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine; 2-Amino-9-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one. Grades: ≥95%. CAS No. 207131-16-6. Molecular formula: C11H13N5O5. Mole weight: 295.25. | |
| 2'OMe-ATP | 2'OMe-ATP is a RNA polymerase inhibitor by being incorporated into RNA. Synonyms: 2'-O-Methyladenosine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C11H18N5O13P3 (free acid). Mole weight: 521.21 (free acid). | |
| 2'-O-Methyl-2-Amino-ATP | 2'-O-Methyl-2-Amino-ATP, a modified adenine nucleotide, is renowned for its widespread use while studying RNA-dependent RNA polymerases and reverse transcriptases in the field of biochemical research. This marvel molecule is also recognized for unravelling the intricacies of ATP-sensitive potassium channels in smooth muscle tissue. Synonyms: 2'-O-Methyl-2-aminoadenosine-5'-Triphosphate; 2'-O-Methyl-2,6-Diaminopurine-ribose-5'-Triphosphate; 2'-O-Methyl-DAP-rTP. Grades: ≥90% by AX-HPLC. Molecular formula: C11H19N6O13P3. Mole weight: 536.2. | |
| 2'-O-Methylcytidine | 2'-O-Methylcytidine is a 2'-substituted nucleoside as a inhibitor of HCV replication. 2'-O-Methylcytidine inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-O-Methylcytidine, O-2-Methylcytidine, Cytidine, 2-O-methyl-, M0259_SIGMA, AIDS338901, CID301382, NSC178026, I07-0058, 2(1H)-Pyrimidinone, 4-amino-1-(2-O-methyl-.beta.-D-arabinofuranosyl)-, 2140-72-9, 35819-07-9. Product Category: Inhibitors. Appearance: Solid. CAS No. 2140-72-9. Molecular formula: C10H15N3O5. Mole weight: 257.24. Purity: 0.96. IUPACName: 4-amino-1-[4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidin-2-one. Canonical SMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)CO)O. Density: 1.68 g/cm³. Product ID: ACM2140729. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2'-O-Methylcytidine | Cytidine analog. Used for preparation of nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase. Synonyms: Cytidine, 2'-O-methyl-; 2'-O-Methyl cytidine; O(2')-Methylcytidine; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-Amino-1-(2-O-methyl-β-D-ribofuranosyl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 2140-72-9. Molecular formula: C10H15N3O5. Mole weight: 257.24. | |
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