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| Product | Description | |
|---|---|---|
| ROCK1 (17-535), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| ROCK2 (5-554), active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| ROCK2 (5-554), active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| ROCK2-IN-6 hydrochloride | ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2762238-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156592A. |  |
| Rock-Constituents (NIM-GBW07114) GSR-12 | Rock-Constituents (NIM-GBW07114) GSR-12. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS011941. Shipping: Room Temperature. | |
| ROCK-IN-1 | ROCK-IN-1 is a potent inhibitor of ROCK , with an IC 50 of 1.2 nM for ROCK2. Uses: Scientific research. Group: Signaling pathways. CAS No. 934387-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00351. | |
| ROCK-IN-5 | ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK , ERK , GSK , and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 692870-25-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153011. | |
| ROCK inhibitor-2 | ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC50 of 75 nM. ROCK inhibitor-2 exhibits antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1127308-52-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119937. | |
| Rock inhibitor y-27632 | Rock inhibitor y-27632. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide. Appearance: white solid. CAS No. 146986-50-7. Molecular formula: C14H21N3O·2HCl. Mole weight: 320.26. Purity: 98%+. IUPACName: 4-[(1R)-1-aminoethyl]-N-pyridin-4-ylcyclohexane-1-carboxamide. Canonical SMILES: CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N. Density: 1.136 g/cm³. Product ID: ACM146986507. Alfa Chemistry ISO 9001:2015 Certified. Categories: 129830-38-2. |  |
| RockPhos | RockPhos. Uses: Ligand used in the palladium-catalyzed c-o bond forming reactions of secondary and primary alcohols with a range of aryl halides. heterocyclic halides and, for the first time, electron-rich aryl halides can be coupled with secondary alcohols. Additional or Alternative Names: ZINC95910984; 2-(Di-t-butylphosphino)-3-methoxy-6-methyl-2'-4'-6'-tri-i-propyl-1,1'-biphenyl; RockPhos, 97%; di-tert-butyl-[6-methoxy-3-methyl-2-(2,4,6-triisopropylphenyl)phenyl]phosphane; Y-200021; Di-tert-butyl(2 inverted exclamation marka,4 inverted exclamation marka,6 inverted exclamation marka-triisopropyl-3-methoxy-6-methyl-[1,1 inverted exclamation marka-biphenyl]-2-yl)phosphine; CVLLAKCGAFNZHJ-UHFFFAOYSA-N; 2-Di-tert-butylphosphino-3-Methoxy-6-Methyl-2',4',6'-triisopropyl-1,1'-biphenyl; SCHEMBL12929986; AX8242285. Product Category: Organic Phosphine Compounds. CAS No. 1262046-34-3. Molecular formula: C31H49OP. Mole weight: 468.706g/mol. IUPACName: ditert-butyl-[6-methoxy-3-methyl-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane. Canonical SMILES: CC1=C(C(=C(C=C1)OC)P(C(C)(C)C)C(C)(C)C)C2=C(C=C(C=C2C(C)C)C(C)C)C(C)C. Product ID: ACM1262046343. Alfa Chemistry ISO 9001:2015 Certified. Categories: Rock phosphate. | |
| Rock Phosphate Coarse Powder | Rock Phosphate Coarse Powder - Agriculture Chemicals. SUPPLIERS TO BUSINESS CUSTOMERS ONLY. |  North America & APAC |
| Anti-phospho-ROCK2 (pTyr722) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ROCK-1 antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ROCK-2 antibody produced in rabbit | ~2 mg/mL, affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ROCK2 antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-ROCK1 antibody produced in mouse | clone 2E2, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Monoclonal Anti-ROCK2 antibody produced in mouse | clone 2A4, purified immunoglobulin, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Moroccan phosphate rock (trace elements) | certified Reference Material. Group: Certified reference materials (crms). | |
| N-tert-Butyloxycarbonyl Y-27632-d4 (ROCK Inhibitor) | Protected Y-27632-d4. A labeled Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. Group: Biochemicals. Alternative Names: trans-4-[ (R) -1-[ (tert-Butyloxycarbonyl) amino]ethyl]-N- (4-pyridyl) cyclohexanecarboxamide-d4; [ (1R) -1- [trans-4- [ (4-Pyridinyl-d4-amino) carbonyl] cyclohexyl] ethyl] -carbamic Acid 1,1-Dimethyethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Phosphate Rock | Phosphate Rock. Uses: For analytical and research use. Group: Process materials, geological, cement & soils. Catalog: APS011211. Shipping: Room Temperature. | |
| Rho Kinase Inhibitor (H-1152, H-1152P, (S) - (+) -2-Methyl-1- [ (4-methyl-5-isoquinolinyl) sulfonyl] homopiperazine, 2HCl, ROCK Inhibitor) | A cell-permeable isoquinolinesulfonamid e compound that acts as a highly specific, reversible, potent, and ATP-competitive inhibitor of G-protein Rho-associated kinase (ROCK; Ki=1.6nM). Inhibits other serine/threonine kinases only at higher concentrations (Ki=630nM for PKA, 9.27 uM for PKC, and 10.1uM for MLCK). Shown to selectively block lysophosphatidic acid-induced, but not PDBu-induced, phosphorylation of myristoylated alanine-rich C kinase substrate (MARCKS) in NT-2 cells (IC50=2.5uM). Reported to be a more potent and selective inhibitor than Y-27632. Group: Biochemicals. Grades: Highly Purified. CAS No. 872543-07-6. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Rho Kinase Inhibitor III, Rockout - CAS 7272-84-6 | The Rho Kinase Inhibitor III, Rockout, also referenced under CAS 7272-84-6, controls the biological activity of Rho Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
| Rho Kinase Inhibitor XIII, RKI-1447 (1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea, Mesylate, 1-(3-Hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea, Methanesulfonate, ROCK Inhibitor XIII) | A cell-permeable pyridylthiazolyl-urea that acts as a potent, ATP site-targeting, Rho Kinase inhibitor (IC50 = 14.5 and 6.2nM against ROCK1 and ROCK2, respectively), displaying much reduced potency against PKA, PKN1/PRK1, p70S6K/RPS6kB1, AKT1, MRCKa/CDC42BPA (85.5%, 80.5%, 61.9%, 56%, and 50.4% inhibition, respectively, by 1uM RKI-1447) or 15 other kinases. Selectively inhibits ROCK-dependent, but not mTORC2-dependent, cellular phosphorylations (effective conc. 0.1-1uM in MDA-MB-231, MDA-MB-468, and H1299 cultures). Shown to be efficacious in suppressing established tumor expansion in a murine ErbB2 mammary cancer model (200mg/kg/day i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S; CH?SO?H. US Biological Life Sciences. | Worldwide |
| Y-27632-d4 Dihydrochloride Hydrate (ROCK Inhibitor) | A labeled Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. Group: Biochemicals. Alternative Names: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide-d4 Dihydrochloride Monohydrate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 06-0334 Graphene Quantum Dots (GQDs), Blue Luminescent | Methane is a colorless odorless gas. It is also known as marsh gas or methyl hydride. It is easily ignited. The vapors are lighter than air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used in making other chemicals and as a constituent of the fuel, natural gas.;Methane is a colorless odorless gas. It is also known as marsh gas or methyl hydride. It is easily ignited. The vapors are lighter than air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used in making other chemicals and as a constituent of the fuel, natural gas.;Methane, refrigerated liquid (cryogenic liquid) is a colorless odorless liquid. Flammable. Water insoluble.;Natural gas, refrigerated liquid (cryogenic liquid) appears as a flammable liquefied gaseous mixture of straight chain hydrocarbons, predominately methane.;Natural gas, [compressed] appears as a flammable gaseous mixture of straight chain hydrocarbons, predominately compressed methane.;GasVapor; Liquid;Liquid;COLOURLESS ODOURLESS COMPRESSED OR LIQUEFIED GAS. Group: Graphenes. CAS No. 1034343-98-0. Product ID: methane. Molecular formula: 16.043g/mol. Mole weight: CH4;CH4;CH4. C. InChI=1S/CH4/h1H4. VNWKTOKETHGBQD-UHFFFAOYSA-N. |  |
| 1,1-Dimethylhydrazine Hydrochloride | 1,1-Dimethylhydrazine Hydrochloride is a toxic volatile hydrazine found in rocket fuel systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 593-82-8. Pack Sizes: 250mg, 1g. Molecular Formula: C2H8N2, Molecular Weight: 60.1. US Biological Life Sciences. | Worldwide |
| 1,8-cineole synthase | Requires Mn2+ or Zn2+. Mg2+ is less effective than either. 1,8-Cineole is the main product from the enzyme with just traces of other monoterpenoids. The oxygen atom is derived from water. The reaction proceeds via linalyl diphosphate and α-terpineol, the stereochemistry of both depends on the organism. However neither intermediate can substitute for geranyl diphosphate. The reaction in Salvia officinalis (sage) proceeds via (-)-(3R)-linalyl diphosphate while that in Arabidopsis (rock cress) proceeds via (+)-(3S)-linalyl diphosphate. Group: Enzymes. Synonyms: 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Enzyme Commission Number: EC 4.2.3.108. CAS No. 110637-19-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5119; 1,8-cineole synthase; EC 4.2.3.108; 110637-19-9; 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Cat No: EXWM-5119. |  |
| (1R)-trans-4-[N-Boc-1-aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide | Protected Y-27632, a Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders. Group: Biochemicals. Alternative Names: [ (1R) -1- [trans-4- [ (4-Pyridinylamino) carbonyl] cyclohexyl] ethyl] carbamic Acid 1,1-Dimethylethyl Ester; N-Boc-Y-27632. Grades: Highly Purified. CAS No. 671816-04-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 2-Amino-6-bromothiazolo[4,5-b]pyrazine | 2-Amino-6-bromothiazolo[4,5-b]pyrazine is derived from 2-Amino-3,5-dibromopyrazine (A604635), which is is used in the preparation of conjugated polymers for neurotoxin detection and is an intermediate in the preparation of rho kinase (ROCK) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 112342-72-0. Pack Sizes: 1g, 5g. Molecular Formula: C5H3BrN4S, Molecular Weight: 231.07. US Biological Life Sciences. | Worldwide |
| 3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea | 3-(4-(1H-pyrazol-4-yl)-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-1-(3-methoxybenzyl)-1-methylurea is a Rho kinase (ROCK) inhibitor. It had excellent enzyme and cellular potency, high kinase selectivity, high aqueous solubility, good porcine corneal penetration, and appropriate DMPK profiles for topical applications as antiglaucoma therapeutics. Synonyms: Urea, N-[(3-methoxyphenyl)methyl]-N-methyl-N'-[4-(1H-pyrazol-4-yl)-2-[2-(1-pyrrolidinyl)ethoxy]phenyl]-; KB-81407. Grade: 95%. CAS No. 1225199-26-7. Molecular formula: C25H31N5O3. Mole weight: 449.55. |  |
| 3-(4-Pyridyl)indole | 3-(4-Pyridyl)indole is a ROCK-I inhibitor (IC50 = 25 μM). Synonyms: 3-(pyridin-4-yl)-1H-indole. Grade: ≥98%. CAS No. 7272-84-6. Molecular formula: C13H10N2. Mole weight: 194.2. | |
| 3-(4-Pyridyl)indole | A cell-permeable indolopyridine compound that acts as a selective, ATP-competitive inhibitor of Rho kinase (ROCK) activity. Group: Biochemicals. Alternative Names: 3-(4-Pyridinyl)-. Grades: Highly Purified. CAS No. 7272-84-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-O-[6-(Benzoylamino)hexyl]-D-myo-inositol-1,2,3,4,6-pentakisphosphate | 5-O-[6-(Benzoylamino)hexyl]-D-myo-inositol-1,2,3,4,6-pentakisphosphate, a bioactive molecule, has proved its worth in the biomedical industry as an effective cancer cell growth inhibitor with potential for treating hepatocellular and colorectal cancers. This powerful compound inhibits ROCK signaling pathways, which are implicated in cancer cell migration and invasion, making it an important target for new drug development. Researchers also believe that 5-O-[6-(Benzoylamino)hexyl]-D-myo-inositol-1,2,3,4,6-pentakisphosphate could help regulate glucose metabolism, opening up possibilities for novel diabetes treatments. Synonyms: myo-Inositol, 5-O-[6-(benzoylamino)hexyl]-, 1,2,3,4,6-pentakis(dihydrogen phosphate). CAS No. 861922-14-7. Molecular formula: C19H34NO22P5. Mole weight: 783.34. | |
| AKT-IN-3 | AKT-IN-3 is a potent and orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 also shows good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. Synonyms: 2-Piperidineacetamide, 5-[[[5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furanyl]carbonyl]amino]-4-(3,4-difluorophenyl)-N-methyl-, (2S,4S,5S)-. CAS No. 2374740-21-1. Molecular formula: C23H23Cl2F2N5O3. Mole weight: 526.36. | |
| AR-13324 analog mesylate | AR-13324 analog mesylate is an analog of AR-13324. AR-13324 is an ROCK and norepinephrine transporter (NET) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095432-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-19346. | |
| AR-13503 | AR-13503 (AR-13324 M1 metabolite) is the hydrolytic metabolite of AR-13324 mesylate. AR-13324 is a ROCK kinase and PKC inhibitor with anti-angiogenic and retinal health-improving effects, showing potential for use in retinal disease research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-13324 M1 metabolite. CAS No. 2309668-15-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12798C. | |
| AS 1892802 | AS 1892802 has been found to be an ATP-competitive ROCK inhibitor and could show analgesic activities at some extent. Synonyms: AS 1892802; AS1892802; AS-1892802; N-[(1S)-2-Hydroxy-1-phenylethyl]-N'-[4-(4-pyridinyl)phenyl]-urea. Grade: ≥99% by HPLC. CAS No. 928320-12-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| AT13148 | AT13148 is an orally active and ATP-competitive, multi- AGC kinase inhibitor with IC 50 s of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1056901-62-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16071. | |
| AT13148 | AT13148 is an orally available multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. It can block phosphorylation of AKT, p70S6K, PKA, ROCK and SGK substrates, and induce apoptosis in cancer cells. Synonyms: AT-13148; (1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol. Grade: >98%. CAS No. 1056901-62-2. Molecular formula: C17H16ClN3O. Mole weight: 313.78. | |
| AT 13148 dihydrochloride | AT13148 is an orally available multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity. It can block phosphorylation of AKT, p70S6K, PKA, ROCK and SGK substrates, and induce apoptosis in cancer cells. Synonyms: (S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol dihydrochloride. Grade: 98%. Molecular formula: C17H16ClN3O.2HCl. Mole weight: 386.70. | |
| Basalt, Pack of 10 | Igneous rock specimen. Ranges in size from 1 x 1" to 1 x 2". Product ID: GEO1012B. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| BAY-549 | BAY-549 (Azaindole 1) is an orally active and ATP-competitive ROCK inhibitor with IC 50 s of 0.6 and 1.1?nM for human ROCK-1 and ROCK-2 , respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ROCK-IN-2; Azaindole 1; TC-S 7001. CAS No. 867017-68-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10319. | |
| BDP5290 | BDP5290, is a potent inhibitor of both ROCK and MRCK with IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively. It has shown to block cancer invasion. Synonyms: 4-Chloro-1-(Piperidin-4-Yl)-N-[3-(Pyridin-2-Yl)-1h-Pyrazol-4-Yl]-1h-Pyrazole-3-Carboxamide; BDP 5290; BDP-5290. Grade: 98%. CAS No. 1817698-21-7. Molecular formula: C17H18ClN7O. Mole weight: 371.82. | |
| Belumosudil | Belumosudil (KD025) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025; SLx-2119. CAS No. 911417-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15307. | |
| Belumosudil mesylate | Belumosudil is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 μM, respectively). Synonyms: KD025 mesylate; SLx-2119 mesylate; 2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)-N-(propan-2-yl)acetamide methanesulfonate (1:1). CAS No. 2109704-99-4. Molecular formula: C27H28N6O5S. Mole weight: 548.62. | |
| Belumosudil mesylate | Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC 50 s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KD025 mesylate; SLx-2119 mesylate. CAS No. 2109704-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15307A. | |
| Brevinin-2HSa | Brevinin-2HSa is an antimicrobial peptide found in Rana hosii (Odorrana hosii, Hose's rock frog). It has antibacterial activity against Gram-positive bacteria: Staphylococcus aureus and Gram-negative bacteria: Escherichia coli. Synonyms: Gly-Leu-Leu-Asp-Ser-Leu-Lys-Asn-Leu-Ala-Ile-Asn-Ala-Ala-Lys-Gly-Ala-Gly-Gln-Ser-Val-Leu-Asn-Thr-Leu-Ser-Cys-Lys-Leu-Ser-Lys-Thr-Cys (Disulfide bridge: Cys27-Cys33). Grade: >97%. Molecular formula: C142H249N41O46S2. Mole weight: 3330.92. | |
| Brevinin-2HSb | Brevinin-2HSb is an antimicrobial peptide found in Rana hosii (Odorrana hosii, Hose's rock frog). It has antibacterial activity against Gram-positive bacteria: Staphylococcus aureus and Gram-negative bacterium: Escherichia coli. Synonyms: Gly-Leu-Leu-Asp-Thr-Leu-Lys-Asn-Met-Ala-Ile-Asn-Ala-Ala-Lys-Gly-Ala-Gly-Gln-Ser-Val-Leu-Asn-Thr-Leu-Ser-Cys-Lys-Leu-Ser-Lys-Thr-Cys (Disulfide bridge: Cys27-Cys33). Grade: >85%. Molecular formula: C142H249N41O46S3. Mole weight: 3362.98. | |
| C-1 | C-1 is a protein kinase inhibitor selecitive for PKG, PKA and PKC (IC50 = 4, 8 and 12 μM, respectively) and is widely used as a ROCK inhibitor. Synonyms: HA 100; HA100; HA-100; 5-Piperazin-1-ylsulfonylisoquinoline; 1-(5-Isoquinolinesulfonyl)piperazine. Grade: ≥99% by HPLC. CAS No. 84468-24-6. Molecular formula: C13H15N3O2S. Mole weight: 277.34. | |
| Calcite | Calcium carbonate appears as white, odorless powder or colorless crystals. Practically insoluble in water. Occurs extensive in rocks world-wide. Ground calcium carbonate (CAS: 1317-65-3) results directly from the mining of limestone. The extraction process keeps the carbonate very close to its original state of purity and delivers a finely ground product either in dry or slurry form. Precipitated calcium carbonate (CAS: 471-34-1) is produced industrially by the decomposition of limestone to calcium oxide followed by subsequent recarbonization or as a by-product of the Solvay process (which is used to make sodium carbonate). Precipitated calcium carbonate is purer than ground calcium carbonate and has different (and tailorable) handling properties.;Limestone is an odorless, white to tan powder.;Limestone (calcium carbonate) that has been recrystallized by metamorphism and is capable of taking a polish. Practically insoluble in water.;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, WetSolid; Liquid; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;White crystalline or amorphous, odourless and tasteless powder;WHITE POWDER OR PELLETS.;White, odorless | |
| Calcium Carbonate Microparticles | Calcium carbonate appears as white, odorless powder or colorless crystals. Practically insoluble in water. Occurs extensive in rocks world-wide. Ground calcium carbonate (CAS: 1317-65-3) results directly from the mining of limestone. The extraction process keeps the carbonate very close to its original state of purity and delivers a finely ground product either in dry or slurry form. Precipitated calcium carbonate (CAS: 471-34-1) is produced industrially by the decomposition of limestone to calcium oxide followed by subsequent recarbonization or as a by-product of the Solvay process (which is used to make sodium carbonate). Precipitated calcium carbonate is purer than ground calcium carbonate and has different (and tailorable) handling properties.;Limestone is an odorless, white to tan powder.;Limestone (calcium carbonate) that has been recrystallized by metamorphism and is capable of taking a polish. Practically insoluble in water.;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, WetSolid; Liquid; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;White crystalline or amorphous, odourless and tasteless powder;WHITE POWDER OR | |
| Calcium Carbonate Nanoparticles | Calcium carbonate appears as white, odorless powder or colorless crystals. Practically insoluble in water. Occurs extensive in rocks world-wide. Ground calcium carbonate (CAS: 1317-65-3) results directly from the mining of limestone. The extraction process keeps the carbonate very close to its original state of purity and delivers a finely ground product either in dry or slurry form. Precipitated calcium carbonate (CAS: 471-34-1) is produced industrially by the decomposition of limestone to calcium oxide followed by subsequent recarbonization or as a by-product of the Solvay process (which is used to make sodium carbonate). Precipitated calcium carbonate is purer than ground calcium carbonate and has different (and tailorable) handling properties.;Limestone is an odorless, white to tan powder.;Limestone (calcium carbonate) that has been recrystallized by metamorphism and is capable of taking a polish. Practically insoluble in water.;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, WetSolid; Liquid; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;White crystalline or amorphous, odourless and tasteless powder;WHITE POWDER OR | |
| Calcium Carbonate Nanoparticles | Calcium carbonate appears as white, odorless powder or colorless crystals. Practically insoluble in water. Occurs extensive in rocks world-wide. Ground calcium carbonate (CAS: 1317-65-3) results directly from the mining of limestone. The extraction process keeps the carbonate very close to its original state of purity and delivers a finely ground product either in dry or slurry form. Precipitated calcium carbonate (CAS: 471-34-1) is produced industrially by the decomposition of limestone to calcium oxide followed by subsequent recarbonization or as a by-product of the Solvay process (which is used to make sodium carbonate). Precipitated calcium carbonate is purer than ground calcium carbonate and has different (and tailorable) handling properties.;Limestone is an odorless, white to tan powder.;Limestone (calcium carbonate) that has been recrystallized by metamorphism and is capable of taking a polish. Practically insoluble in water.;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, WetSolid; Liquid; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;White crystalline or amorphous, odourless and tasteless powder;WHITE POWDER OR | |
| Calcium Carbonate Nanopowder | Calcium carbonate appears as white, odorless powder or colorless crystals. Practically insoluble in water. Occurs extensive in rocks world-wide. Ground calcium carbonate (CAS: 1317-65-3) results directly from the mining of limestone. The extraction process keeps the carbonate very close to its original state of purity and delivers a finely ground product either in dry or slurry form. Precipitated calcium carbonate (CAS: 471-34-1) is produced industrially by the decomposition of limestone to calcium oxide followed by subsequent recarbonization or as a by-product of the Solvay process (which is used to make sodium carbonate). Precipitated calcium carbonate is purer than ground calcium carbonate and has different (and tailorable) handling properties.;Limestone is an odorless, white to tan powder.;Limestone (calcium carbonate) that has been recrystallized by metamorphism and is capable of taking a polish. Practically insoluble in water.;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; Liquid; OtherSolid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;DryPowder; DryPowder, Liquid; DryPowder, OtherSolid; DryPowder, PelletsLargeCrystals; DryPowder, PelletsLargeCrystals, Liquid; DryPowder, WetSolid; Liquid; OtherSolid; OtherSolid, Liquid; PelletsLargeCrystals; WetSolid; WetSolid, Liquid; WetSolid, OtherSolid;White crystalline or amorphous, odourless and tasteless powder;WHITE POWDER OR PEL | |
| Carbohydrazide | Carbohydrazide. Uses: Boiler feed system, rocket propellant components. Additional or Alternative Names: Carbohydrazide; 1,3-diaminourea; 1,3-Diaminourea. Appearance: white crystalline. CAS No. 497-18-7. Molecular formula: CH6N4O. Mole weight: 90.09. Purity: 0.98. IUPACName: 1,3-diaminourea. Canonical SMILES: C(=O)(NN)NN. Density: 1.02. ECNumber: 207-837-2. Product ID: ACM497187. Alfa Chemistry ISO 9001:2015 Certified. | |
| Carbon nanotubes conductive water-based coatings | Methane is a colorless odorless gas. It is also known as marsh gas or methyl hydride. It is easily ignited. The vapors are lighter than air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used in making other chemicals and as a constituent of the fuel, natural gas.;Methane is a colorless odorless gas. It is also known as marsh gas or methyl hydride. It is easily ignited. The vapors are lighter than air. Under prolonged exposure to fire or intense heat the containers may rupture violently and rocket. It is used in making other chemicals and as a constituent of the fuel, natural gas.;Methane, refrigerated liquid (cryogenic liquid) is a colorless odorless liquid. Flammable. Water insoluble.;Natural gas, refrigerated liquid (cryogenic liquid) appears as a flammable liquefied gaseous mixture of straight chain hydrocarbons, predominately methane.;Natural gas, [compressed] appears as a flammable gaseous mixture of straight chain hydrocarbons, predominately compressed methane.;GasVapor; Liquid;Liquid;COLOURLESS ODOURLESS COMPRESSED OR LIQUEFIED GAS. Group: Carbon nanotubes conductive water-based coatings. CAS No. 308068-56-6. Pack Sizes: 1kg. Product ID: methane. Molecular formula: 16.043g/mol. Mole weight: CH4. InChI=1S/CH4/h1H4. VNWKTOKETHGBQD-UHFFFAOYSA-N. | |
| CAY10622 | Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine kinases. It is involved mainly in regulating the shape and movement of cells by acting on the cytoskeleton. Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions. CAY10622 is a potent, ureidobenzamide inhibitor of ROCK-I and ROCK-II kinases with IC50 values of 6 and 4 nM, respectively. Synonyms: CAY 10622; CAY-10622. Grade: ≥98%. CAS No. 1038549-25-5. Molecular formula: C25H25N5O3. Mole weight: 443.5. | |
| CCG-224406 | CCG-224406 is a highly selective and potent inhibitor of G Protein-Coupled Receptor Kinase 2 (IC50= 130 nM), with 700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1. Synonyms: CCG 224406; CCG224406; N-(1H-Indazole-5-yl)-2-oxo-4-[3-(2,6-dimethoxybenzylcarbamoyl)-4-fluorophenyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxamide. Grade: >98%. CAS No. 1870843-22-3. Molecular formula: C29H27FN6O5. Mole weight: 558.57. | |
| CCG258208 hydrochloride | CCG258208 (GRK2-IN-1) hydrochloride is a potent and selective GRK2 (G protein-coupled receptor kinase 2) inhibitor (IC50=30 nM) while maintaining 230-fold selectivity over GRK5 (IC50=7.09 ?M) and more than 2500-fold selectivity over GRK1 (IC50=87.3 ?M), PKA, and ROCK1. CCG258208 hydrochloride can be used in heart failure research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GRK2-IN-1 hydrochloride. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109562A. | |
| Cell Cycle Compound Library | A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); - Targets include CDK, ROCK, Aurora Kinase, ATM/ATR, DNA-PK, DNA/RNA Synthesis, etc. ; - Effective tool for research in cell cycle and related diseases, such as cancer, cardiovascular diseases, inflammation, neurodegenerative diseases, etc. ; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8100. Categories: Cell Cycle Compounds Libraries. |  |
| Ceresin | Ceresin is a white-to-yellow waxy mixture of hydrocarbons obtained by purification of ozokerite. It occurs as odorless, tasteless, amorphous (noncrystalline) brittle, waxy cakes or pastilles. Synonyms: Cera mineralis alba; ceresine; ceresine wax; ceresin wax; cerin; cerosin; Cirashine CS; earth wax; GS-Ceresin; Koster Keunen Ceresine; mineral wax; purified ozokerite; Ross Ceresine Wax; white ceresin wax; white ozokerite wax. CAS No. 8001-75-0. Product ID: PE-0605. Category: Coating Agents; Opacifier; Stabilizing Agents; Stiffening Agents. Product Keywords: Other Materials; Stabilizers; PE-0605; Ceresin; Coating Agents; Opacifier; Stabilizing Agents; Stiffening Agents; ; 8001-75-0. UNII: Q1LS2UJO3A. Grade: Pharmceutical Excipients. Administration route: Topical. Dosage Form: Topical ointments; vaginal emulsions and cream. Stability and Storage Conditions: Ceresin should be stored in well-closed containers in a cool, dry, well-ventilated place, away from extreme heat and strong oxidizing agents. Source and Preparation: Ceresin is prepared by extraction and purification of the native mineral fossil wax ozokerite, which is derived from coal and shale.Ozokerite is mined from deposits in various localities around the world. It is found as irregular mineral veins or as a black mass in clay strata. Mined ozokerite is heated to melt it, and any earth or rock is removed. If necessary, it is heated to 115-120°C to remove any moisture |  |
| Chroman 1 | Chroman 1, a chroman-based compound, is an effective ROCK II inhibitor which could probably influence the cell motility involved in sorts of disorders. Uses: Chroman 1is an effective rock ii inhibitor which could probably influence the cell motility involved in sorts of disorders. Synonyms: Chroman 1; Chroman-1; Chroman1. (3S)-N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-6-methoxy-3,4-dihydro-2H-chromene-3-carboxamide; chroman1; 1273579-40-0; CHEMBL3221807; 3543AH; CS-0775; CS 0775; CS0775. Grade: 95%. CAS No. 1273579-40-0. Molecular formula: C24H28N4O4. Mole weight: 436.50. | |
| Chroman 1 | Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1273579-40-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15392. | |
| Chroman 1 dihydrochloride | Chroman 1 dihydrochloride is a highly potent and selective ROCK inhibitor. Chroman 1 dihydrochloride is more potent against ROCK2 (IC50 = 1 pM) than ROCK1 (IC50 = 52 pM). Molecular formula: C24H30Cl2N4O4. Mole weight: 509.43. | |
| CMPD101 | CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKC? with IC50s of 3.1 ?M , 2.3 ?M, 1.4 ?M and 8.1 ?M, respectively. CMPD101 can be used for the study of heart failure[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865608-11-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103045. | |
| Cotosudil | Cotosudil is a Rho-associated (ROCK) kinase inhibitor. It can be used for glaucoma or ocular hypertension research. Synonyms: (R)-6-((2-Methyl-1,4-diazocan-1-yl)sulfonyl)isoquinoline. Grade: 99%. CAS No. 1258833-31-6. Molecular formula: C16H21N3O2S. Mole weight: 319.42. | |
| CRT0066854 | CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCΙ , PKCζ , and ROCK-II kinases with IC 50 values of 132 nM, 639 nM, and 620 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1438881-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18713. | |
| CRT0066854 hydrochloride | CRT0066854 hydrochloride is a potent and selective atypical PKC s inhibitor. CRT0066854 is against full-length (FL) PKCΙ , PKCζ , and ROCK-II kinases with IC 50 values of 132 nM, 639 nM, and 620 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250019-91-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18713A. | |
| CRT0066854 hydrochloride | CRT0066854 is against full-length (FL) PKCΙ, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively. Synonyms: CRT 0066854 hydrochloride. CAS No. 2250019-91-9. Molecular formula: C24H27Cl2N5S. Mole weight: 452.01. | |
| Dimethyl Phthalate | Dimethyl phthalate is a organic compound with molecular formula (C2H3O2)2C6H4. The methyl ester of phthalic acid, it is a Colorless liquid that is soluble in organic solvents.Dimethyl phthalate is used as an insect repellent for mosquitoes and flies. It is also an ectoparasiticide and has many other uses, including in solid rocket propellants, and plastics. Its LD50 is 8 200 mg/kg (rats, oral). Uses: Dmp can be used to plasticize cellulose acetate which can be further used in the production of laminated safety glass for flight helmets and goggles. it can be used as a plasticizer that forms complexes with polyvinyl alcohol (pva) and lithium salts for the development of solid polymer electrolyte (spe) for solar cell (sc) s. it may also be used as a mixture of polymeric solvents which can be used in the preparation of polyvinylidene fluoride (pvdf). Group: Plastic additivespolymersplasticizers. Alternative Names: DMP. CAS No. 131-11-3. Pack Sizes: Packaging 1, 4 L in poly bottle. Product ID: dimethyl benzene-1,2-dicarboxylate. Molecular formula: 194.2. Mole weight: C10H10O4. COC(=O)C1=CC=CC=C1C(=O)OC. InChI=1S/C10H10O4/c1-13-9 (11)7-5-3-4-6-8 (7)10 (12)14-2/h3-6H, 1-2H3. NIQCNGHVCWTJSM-UHFFFAOYSA-N. 98%. | |
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