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| Product | Description | |
|---|---|---|
| Scopolamine | Scopolamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-34-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C17H21NO4. US Biological Life Sciences. |  Worldwide |
| Scopolamine β-D-Glucuronide | A metabolite of Scopolamine. Group: Biochemicals. Alternative Names: (2S)-3-[[(1α,2 β,4 β,5α,7 β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl]oxy]-3-oxo-2-phenylpropyl β-D-Glucopyranosiduronic Acid; (-)-Scopolamine 9'-glucuronide; Scopolamine O- β-D-glucuronide. Grades: Highly Purified. CAS No. 17660-02-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Scopolamine β-D-Glucuronide | A metabolite of scopolamine. Scopolamine is an acetylcholine antagonist used in treatment of motion sickness, postoperative nausea and vomiting, antispasmodic, mydriatic, preanesthetic medicant. Synonyms: (2S)-3-[[(1α, 2β, 4β, 5α, 7β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl]oxy]-3-oxo-2-phenylpropyl β-D-Glucopyranosiduronic Acid; (-)-Scopolamine 9'-glucuronide; Scopolamine O-β-D-glucuronide. Grades: > 95%. CAS No. 17660-02-5. Molecular formula: C23H29NO10. Mole weight: 479.48. |  |
| Scopolamine butylbromide | Scopolamine butylbromide is a competitive antagonist of muscarinic acetylcholine receptor (mAChR) with an IC50 of 55. Uses: Scientific research. Group: Natural products. Alternative Names: Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide. CAS No. 149-64-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0340. |  |
| Scopolamine butylbromide | Scopolamine butylbromide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 149-64-4. Molecular Formula: C21H30BrNO4. Mole Weight: 440.38. Catalog: APB149644. |  |
| Scopolamine butylbromide EP impurity G bromide salt | Scopolamine butylbromide EP impurity G bromide salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 92714-23-3. Molecular Formula: C21H28BrNO3. Mole Weight: 422.36. Catalog: APB92714233. | |
| Scopolamine butylbromide Impurity 6 | Scopolamine butylbromide Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 155-41-9. Molecular Formula: C21H30BrNO4. Mole Weight: 440.38. Catalog: APB155419. | |
| Scopolamine-d3 hydrobromide | Scopolamine-d 3 (hydrobromide) is the deuterium labeled Scopolamine hydrobromide[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Hyoscine-d3 hydrobromide. CAS No. 1279037-70-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W010892S. | |
| Scopolamine-d3 Hydrobromide | An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Group: Biochemicals. Alternative Names: (α S) -α - (Hydroxymethyl) benzeneacetic Acid (1α,2 β,4 β,5α,7 β)-9-(Methyl-d3)-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester; Hydrobromide; Scopolammonium-d3 Bromide. Grades: Highly Purified. CAS No. 1279037-70-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Scopolamine-d3 Sulfate | Scopolamine-d3 Sulfate. Group: Biochemicals. Alternative Names: α -[ (Sulfooxy) methyl]benzeneacetic Acid C-[(1α, 2α, 4α, 5α, 7 β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl] Ester-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H18D3NO7S, Molecular Weight: 386.43. US Biological Life Sciences. | Worldwide |
| Scopolamine EP Impurity A | Scopolamine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4684-28-0. Molecular Formula: C16H19NO4. Mole Weight: 289.33. Catalog: APB4684280. | |
| Scopolamine hydrobromide trihydrate | Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Hyoscine hydrobromide trihydrate. CAS No. 6533-68-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W010892. | |
| Scopolamine Impurity 1 | Scopolamine Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 64069-63-2. Molecular Formula: C17H21NO4. Mole Weight: 303.36. Catalog: APB64069632. | |
| Scopolamine Impurity 2 | Scopolamine Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H22BrNO2. Mole Weight: 292.22. Catalog: APB12331. | |
| Scopolamine Methyl Bromide | Scopolamine Methyl Bromide. Group: Biochemicals. Alternative Names: (1α,2 β,4 β,5α,7 β )-7-[(2S)-3-Hydroxy-1-oxo-2-phenylpropoxy]-9, 9-dimethyl-3-oxa-9-azoniatricyclo[3. 3. 1. 02, 4]nonane; 6 β,7 β-Epoxy-3α-hydroxy-8-methyl-1αH,5αH-tropanium Bromide (-)-Tropate; [7(S)-(1α,2 β,4 β,5α,7 β )]-7-(3-Hydroxy-1-oxo-2-phenylpropoxy)-9, 9-dimethyl-3-oxa-9-azoniatricyclo[3. 3. 1. 02, 4]nonane Bromide; (1α,2 β,4 β,5α,7 β )-7-[(2S)-3-Hydroxy-1-oxo-2-phenylpropoxy]-9, 9-dimethyl-3-oxa-9-azoniatricyclo[3. 3. 1. 02, 4]nonane Bromide; N-Methylscopolammonium Bromide; 3-Oxa-9-azatricyclo[3.3.1.02, 4]nonane, 3-oxa-9-azoniatricyclo[3. 3. 1. 02, 4]nonane deriv.; (-)-Tropic Acid Ester with 6 β,7 β-Epoxy-3α-hydroxy-8-methyl-1αH,5αH-tropanium Bromide (8CI); (-)-Scopolamine Methobromide; (-)-Scopolamine Methyl Bromide; Ampyrox; Blocan; Diopal; Epoxymethamine Bromide; Epoxytropine Tropate Methylbromide; Holopon; Hyoscine Methobromide; Hyoscine Methyl Bromide; Lescopine Bromide; Mescopil; Methscopolamin Bromide; Methscopolamine Bromide; Methylscopolamine Bromide; N-Methylscopolamine Bromide; N-Methylscopolaminium Bromide; NSC 120606; NSC 61809; Neo-Avagal; Nutrop; Pamine; Pamine Bromide; Paraspan; Proscomide; Restropin; Scopolamine Methobromide; Scopolamine Methyl Bromide; U 5036. Grades: Highly Purified. CAS No. 155-41-9. Pack Sizes: 1g. Molecular Formula: C18H24BrNO4, Molecular Weight: 398.29. US Biological Life Sciences. | Worldwide |
| Scopolamine nitrate | Scopolamine (nitrate) is an organic compound commonly used in neuroscience research and pharmacology research. It can be used to study the role and structure of acetylcholine receptors, and is widely used in drug development and research in related fields. In addition, this compound is also used as a substrate or catalyst in certain biochemical reactions. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Methscopolamine nitrate. CAS No. 6106-46-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W127702. | |
| Scopolamine N-Oxide | An impurity of scopolamine. Scopolamine is an acetylcholine antagonist used in treatment of motion sickness, postoperative nausea and vomiting, antispasmodic, mydriatic, preanesthetic medicant. Uses: Anticholinergic agent. Synonyms: (αS)-α-(Hydroxymethyl)benzeneacetic Acid (1α, 2β, 4β, 5α, 7β)-9-Methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester; 6β,7β-Epoxy-1αH,5αH-tropan-3α-ol (-)-Tropate 8-Oxide; [7(S)-(1α, 2β, 4β, 5α, 7β)]-α-(Hydroxymethyl)benzeneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester N-Oxide; Scopolamine, N-Oxide; 3-Oxa-9-azatricyclo[3.3.1.02,4]nonane Benzeneacetic Acid Deriv.; Genoscopolamine; Hyoscinamine Oxide; Hyoscine N-Oxide; Hyoscineamine Oxide; Oxicopolamina; Scolamine; Scolen; Scopodex; Scopolamine aminoxide; Seamalin; Seronex. Grades: > 95%. CAS No. 97-75-6. Molecular formula: C17H21NO5. Mole weight: 319.36. | |
| Scopolamine N-Oxide | Scopolamine N-Oxide. Group: Biochemicals. Alternative Names: (α S) -α - (Hydroxymethyl) benzeneacetic Acid (1α,2 β,4 β,5α,7 β)-9-Methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester; 6 β,7 β-Epoxy-1αH,5αH-tropan-3α-ol (-)-Tropate 8-Oxide; [7(S)-(1α,2 β,4 β,5α,7 β ) ]-α - (Hydroxymethyl) benzeneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester N-Oxide; Scopolamine, N-Oxide; 3-Oxa-9-azatricyclo[3.3.1.02, 4]nonane Benzeneacetic Acid Deriv.; Genoscopolamine; Hyoscinamine Oxide; Hyoscine N-Oxide; Hyoscineamine Oxide; Oxicopolamina; Scolamine; Scolen; Scopodex; Scopolamine aminoxide; Seamalin; Seronex. Grades: Highly Purified. CAS No. 97-75-6. Pack Sizes: 100mg. Molecular Formula: C17H21NO5, Molecular Weight: 319.35. US Biological Life Sciences. | Worldwide |
| Scopolamine N-Oxide | Scopolamine N-Oxide. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS012058. Format: Neat. Shipping: Room Temperature. | |
| Scopolamine N-Oxide-d3 | Scopolamine N-Oxide-d3. Group: Biochemicals. Alternative Names: (α S) -α - (Hydroxymethyl) benzeneacetic Acid (1α,2 β,4 β,5α,7 β)-9-Methyl-9-oxido-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester-d3; 6 β,7 β-Epoxy-1αH,5αH-tropan-3α-ol (-)-Tropate 8-Oxide-d3; [7(S)-(1α,2 β,4 β,5α,7 β ) ]-α - (Hydroxymethyl) benzeneacetic Acid 9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester N-Oxide-d3; Scopolamine, N-Oxide-d3; 3-Oxa-9-azatricyclo[3.3.1.02, 4]nonane Benzeneacetic Acid Deriv-d3; Genoscopolamine-d3; Hyoscinamine Oxide-d3; Hyoscine N-Oxide-d3; Hyoscineamine Oxide-d3; Oxicopolamina-d3; Scolamine-d3; Scolen-d3; Scopodex-d3; Scopolamine aminoxide-d3; Seamalin-d3; Seronex-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H18D3NO5, Molecular Weight: 322.37. US Biological Life Sciences. | Worldwide |
| Scopolamine Sulfate | Scopolamine Sulfate. Group: Biochemicals. Alternative Names: α -[ (Sulfooxy) methyl]benzeneacetic Acid C-[(1α, 2α, 4α, 5α, 7 β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl] Ester. Grades: Highly Purified. CAS No. 866926-81-0. Pack Sizes: 25mg. Molecular Formula: C17H21NO7S, Molecular Weight: 383.42. US Biological Life Sciences. | Worldwide |
| Aposcopolamine | A urinary metabolite of Scopolamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 535-26-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Aposcopolamine, Hydrochloride Salt | A urinary metabolite of Scopolamine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| DL-Scopolamine Hydrobromide | Molecular Formula: C17H22BrNO4Molecular Weight:384.27. Group: Biochemicals. Alternative Names: Hyosol, Scopamin, Scopos, Tranaxine. Grades: Plant Grade. CAS No. 114-49-8. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C17H22BrNO4, Molecular Weight: 384.27. US Biological Life Sciences. | Worldwide |
| Methscopolamine bromide | Methscopolamine Bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Scopolamine methyl bromide; Hyoscine methyl bromide. CAS No. 155-41-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0344. | |
| Methscopolamine bromide | Methscopolamine is a muscarinic acetylcholine receptor blocker. Uses: Parasympatholytics. Synonyms: N-methyl scopolamine bromide; scopolamine methyl bromide; DD-234; DD 234; DD234; Pamine. Grades: >98%. CAS No. 155-41-9. Molecular formula: C18H24BrNO4. Mole weight: 398.29. | |
| N-Butyl nor scopolamine hydrochloride | N-Butyl nor scopolamine hydrochloride. Group: Biochemicals. Alternative Names: [7 (S) - (1a2b, 4b, 5a, 7b) ]-a- (Hydroxymethyl) benzeneacetic Acid. Grades: Highly Purified. CAS No. 22235-98-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H28ClNO4. US Biological Life Sciences. | Worldwide |
| N-Butyl Scopolamine Bromide (N-Butyl Hyoscine Bromide) | Cas No. 149-64-4. | |
| Nor Scopolamine | Nor Scopolamine. Uses: For analytical and research use. Group: Impurity standards. CAS No. 4684-28-0. Pack Sizes: 5MG. Molecular Formula: C16H19NO4. Mole Weight: 289.33. Catalog: APS4684280B. SMILES: OC[C@@H] (C (=O)O[C@H]1C[C@@H]2N[C@H] (C1)[C@H]3O[C@@H]23)c4ccccc4. Format: Neat. Shipping: Room Temperature. | |
| Nor Scopolamine | Scopolamine metabolite. Group: Biochemicals. Alternative Names: 6 β,7 β-Epoxy-1αH,5αH-nortropan-3α-ol (-)-Tropate Ester; [7(S)-(1α,2 β,4 β,5α,7 β)]-α-(Hydroxymethyl)-benzeneacetic Acid 3-Oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester; Norhyoscine. Grades: Highly Purified. CAS No. 4684-28-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| O-Acetyl-(-)-norscopolamine | Nor Scopolamine derivative. Group: Biochemicals. Alternative Names: [7(S)-(1α,2 β,4 β,5α,7 β)]- α-[(Acetyloxy)methyl]-benzeneacetic Acid 3-Oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester. Grades: Highly Purified. CAS No. 5027-68-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| O-Acetyl Scopolamine Hydrobromide | Scopolamine Hydrobromide derivative. An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Group: Biochemicals. Alternative Names: 6 β,7 β-Epoxy-1αH,5αH-tropan-3α-ol (-)-Tropate (Ester) Acetate Hydrobromide; Scopolamine Acetate Hydrobromide; (-)-Scopolamine Acetate Hydrobromide; NSC 172233; O-Acetyl-(-)-hyoscine Hydrobromide. Grades: Highly Purified. CAS No. 5027-67-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| (-)-Scopolamine Hydrobromide | (-)-Scopolamine hydrobromide is a competitive inhibitor of acetylcholine muscarinic receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 114-49-8. Pack Sizes: 1g, 2.5g. Molecular Formula: C17H22BrNO4, Molecular Weight: 384.27. US Biological Life Sciences. | Worldwide |
| (-)-Scopolamine Hydrobromide Trihydrate | Scopolamine Hydrobromide Hydrate is an acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant. Group: Biochemicals. Alternative Names: Hyoscine Hydrobromide Hydrate; (1α,2 β,4 β,5α,7 β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl Ester Hydrobromide Hydrate; Scopolammonium Bromide Hydrate. Grades: Highly Purified. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| (-)-Scopolamine hydrochloride | (-)-Scopolamine hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 55-16-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C17H21NO4·ClH. US Biological Life Sciences. | Worldwide |
| (-)-Scopolamine Methyl Bromide | (-)-Scopolamine methyl bromide is a competitive antimuscarinic compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 155-41-9. Pack Sizes: 1g, 2.5g. Molecular Formula: C18H24BrNO4, Molecular Weight: 398.29. US Biological Life Sciences. | Worldwide |
| AF-DX 384 | AF-DX 384 is a selective antagonist of M2 and M4 muscarinic acetylcholine receptors ( K i s =6.03 and 10 nM, respectively) [1]. AF-DX 384 reverses deficits in novel object recognition and passive avoidance in aged rats, as well as in young rats with impairments induced by scopolamine [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 118290-26-9. Pack Sizes: 5 mg. Product ID: HY-107652. | |
| AS 19 | Potent 5-HT7 receptor agonist (IC50 = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced. Group: Biochemicals. Alternative Names: (2S) - (+) -5- (1, 3, 5-Trimethylpyrazol-4-yl) -2- (dimethylamino) tetralin. Grades: Highly Purified. CAS No. 1000578-26-6. Pack Sizes: 10mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 283.41. US Biological Life Sciences. | Worldwide |
| BGC 20-761 | BGC 20-761 is a selective, high affinity 5-HT6 antagonist (Ki = 20 nM). BGC 20-761 was shown to reverse the amnesic effects of scopolamine and enhance memory consolidation in a rat model. Synonyms: BGC-20-761; BGC 20 761; 5-Methoxy-N,N-dimethyl-2-phenyl-1H-indole-3-ethanamine; N,N-Dimethyl-2-(5-methoxy-2-phenylindol-3-yl)ethylamine. Grades: ≥98% by HPLC. CAS No. 17375-63-2. Molecular formula: C19H22N2O. Mole weight: 294.39. | |
| N-Butylscopolammonium Bromide | Anticholinergic. Antispasmodic. Group: Biochemicals. Alternative Names: 7(S)-(1α,2 β,4 β,5α,7 β )]-9-Butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azoniatricyclo[3. 3. 1. 02, 4]nonane Bromide;(-)-Scopolamine Butylbromide; Amisepan; Buscopan; N-Butylhyoscinium Bromide; Stibron; Tirantil; Hyoscine Butyl Bromide. Grades: Highly Purified. CAS No. 149-64-4. Pack Sizes: 1g, 5g. Molecular Formula: C??H??BrNO?, Molecular Weight: 440.37. US Biological Life Sciences. | Worldwide |
| N-Butylscopolammonium Bromide-d9 | N-Butylscopolammonium Bromide-d9. Group: Biochemicals. Alternative Names: 7(S)-(1α,2 β,4 β,5α,7 β )]-9-Butyl-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azoniatricyclo[3. 3. 1. 02, 4]nonane Bromide;(-)-Scopolamine Butylbromide-d9; Amisepan-d9; Buscopan-d9; N-Butylhyoscinium Bromide-d9; Stibron-d9; Tirantil-d9. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C21H21D9BrNO4, Molecular Weight: 449.37. US Biological Life Sciences. | Worldwide |
| PP2A Activating Ligand, ITH12246 | A cell-permeable, relatively non-toxic, 1,8-naphthyridine derived compound that blocks the inhibitory effect of protein phosphatase inhibitors, such as okadaic acid, on protein phosphatase 2A (PP2A). Exhibits blood-brain barrier permeability. Protects neurons against beta-amyloid peptides (Ab1-42) toxicity and okadaic acid-induced tau hyperphosphorylation. Also protects against rotenone and oligomycin A induced neurotoxicity in SH-SY5Y neuroblastoma cells (at ~300nM). Prevents the development of glutamate-induced neuronal lesions in rat hippocampal slices by up-regulating PP2A (~3uM). Shown to reverse the scopolamine-induced memory loss in mice (~10mg/kg i.p) and significantly reduces the infarct volume in an animal model of stroke (~2.5mg/kg). Also acts as an inhibitor of acetylcholinesterase activity in Electrophorus electricus (IC50 = 60nM) and human erythrocytes (IC50 = 780nM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. | Worldwide |
| Pseudoginsenoside F11 | Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. Uses: Scientific research. Group: Natural products. Alternative Names: Ginsenoside A1. CAS No. 69884-00-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0541. | |
| RJR-2403 | At concentrations up to 1 mM, RJR-2403 does not significantly activate nAChRs in PC12 cells, muscle type nAChRs or muscarinic receptors. Dose-response curves for agonist-induced ileum contraction indicate that RJR-2403 is less than one-tenth as potent as nicotine with greatly reduced efficacy. RJR-2403 does not antagonize nicotine-stimulated muscle or ganglionic nAChR function (IC50 > 1 mM). Chronic exposure of M10 cells to RJR-2403 (10 microM) results in an up-regulation of high-affinity nAChRs phenomenologically similar to that seen with nicotine. RJR-2403 significantly improved passive avoidance retention after scopolamine-induced amnesia and enhanced both working and reference memory in rats with ibotenic acid lesions of the forebrain cholinergic projection system in an 8-arm radial maze paradigm. By comparison, RJR-2403 was 15 to 30-fold less potent than nicotine in decreasing body temperature, respiration, Y-maze rears and crosses and acoustic startle response. Metanicotine was about 5-fold less potent than nicotine in the tail-flick test after s.c administration, but slightly more potent after central administration. Synonyms: Rivanicline; Metanicotine; RJR-2403; RJR 2403; RJR2403; Metanicotine; Rivanicline oxalate. Grades: >98%. CAS No. 15585-43-0. Molecular formula: C10H14N2. Mole weight: 162.23. | |
| SC-53116 Hydrochloride Hydrate | SC-53116 is a 5-HT4 receptor partial agonist. SC-53116 has been shown to ameliorate scopolamine-induced impairment in learning in rats at a does of 10 μg/rat i.c.v and increase population spike amplitude in the CA1 and CA3 fields of the hippocampus at the same concentration. Group: Biochemicals. Alternative Names: 4-Amino-5-chloro-N-[[(1S,7aS)-hexahydro-1H-pyrrolizin-1-yl]methyl]-2-methoxybenzamide Hydrochloride Hydrate; (1S-cis)-4-Amino-5-chloro-N-[(hexahydro-1H-pyrrolizin-1-yl)methyl]-2-methoxybenzamide Hydrochloride Hydrate. Grades: Highly Purified. CAS No. 879208-42-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Tropine | Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent [1]. Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine [2]. Uses: Scientific research. Group: Natural products. CAS No. 120-29-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N7061. | |
| tropinone reductase I | Also oxidizes other tropan-3α-ols, but not the corresponding β-derivatives. This enzyme along with EC 1.1.1.236, tropinone reductase II, represents a branch point in tropane alkaloid metabolism.Tropine (the product of EC 1.1.1.206) is incorporated into hyoscyamine and scopolamine whereas pseudotropine (the product of EC 1.1.1.236) is the first specific metabolite on the pathway to the calystegines. Both enzymes are always found together in any given tropane-alkaloid-producing species, have a common substrate, tropinone, and are strictly stereospecific. Group: Enzymes. Synonyms: tropine dehydrogenase; tropinone reductase (ambiguous); TR-I. Enzyme Commission Number: EC 1.1.1.206. CAS No. 118390-87-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0110; tropinone reductase I; EC 1.1.1.206; 118390-87-7; tropine dehydrogenase; tropinone reductase (ambiguous); TR-I. Cat No: EXWM-0110. |  |
| tropinone reductase II | This enzyme along with EC 1.1.1.206, tropine dehydrogenase, represents a branch point in tropane alkaloid metabolism.Tropine (the product of EC 1.1.1.206) is incorporated into hyoscyamine and scopolamine whereas pseudotropine (the product of EC 1.1.1.236) is the first specific metabolite on the pathway to the calystegines. Both enzymes are always found together in any given tropane-alkaloid-producing species, have a common substrate, tropinone, and are strictly stereospecific. Group: Enzymes. Synonyms: tropinone (ψ-tropine-forming) reductase; pseudotropine forming tropinone reductase; tropinone reductase (ambiguous); TR-II. Enzyme Commission Number: EC 1.1.1.236. CAS No. 136111-61-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0143; tropinone reductase II; EC 1.1.1.236; 136111-61-0; tropinone (ψ-tropine-forming) reductase; pseudotropine forming tropinone reductase; tropinone reductase (ambiguous); TR-II. Cat No: EXWM-0143. | |
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