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A lignan isolated from the bark of Fagara plants and from sesame oil. Studies show that it has has multiple functions such as cholesterol-lowering and anti-hypertensive activities. It induces the expression of the gene for aldehyde dehydrogenase, an alcohol-metabolizing enzyme suggesting it regulates the metabolism of lipids, xenobiotics, and alcohol at the mRNA level. Group: Biochemicals. Alternative Names: (1S,3aR,4S,6aR)-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole; (+)-Sesamin; ; Fagarol; NSC 36403; Sesamin; Sezamin; d-Sesamin; 5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole; [1S-(1α, 3aα, 4α, 6aα)]-5, 5'-(Tetrahydro-1H, 3H-furo[3, 4-c]furan-1, 4-diyl)bis-1, 3-benzodioxole; Tetrahydro-1, 4-bis[3, 4- (methylenedioxy) phenyl]-1H, 3H-furo[3, 4-c]furan; (1S, 3aR, 4S, 6aR) -Tetrahydro-1, 4-bis[3, 4- (methylenedioxy) phenyl]-1H, 3H-Furo[3, 4-c]furan. Grades: Highly Purified. CAS No. 607-80-7. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Sesamin
Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 607-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0121.
epi-sesamin monocatechol
epi-sesamin monocatechol. Group: Biochemicals. Alternative Names: 4-[(3aR,6aR)-4-(1,3-Benzodioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,2-benzenediol. Grades: Highly Purified. CAS No. 1105568-81-7. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C19H18O6. US Biological Life Sciences.
Worldwide
(-)-Sesamin
(-)-Sesamin isolated from Asarum forbesii Maxim, is an isomer of Sesamin. Sesamin is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13079-95-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0121A.
Black Sesame Seed Extract. Applications: Used for health care products, dietary supplements, herb medecine and cosmetic industry. Group: Others. Synonyms: Black Sesame Seed Extract; 607-80-7; Sesamum indicum L. CAS No. 607-80-7. Purity: 10%-98% Sesamin by HPLC, 5-10:1 by TLC. Appearance: White or Light yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Seed. Species: Sesamum indicum L. Black Sesame Seed Extract; 607-80-7; Sesamum indicum L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-137.
rac Enterodiol
A compound closely related to Enterolactone. A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: (2R,3R)-rel-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol; (R*,R*)-(±)-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol. Grades: Highly Purified. CAS No. 77756-22-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Enterodiol-d6
Isotope labelled rac Enterodiol, a compound closely related to Enterolactone (E558950). A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: (2R,3R)-rel-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol-d6; (R*,R*)-(±)-2,3-Bis[(3-hydroxyphenyl)methyl]-1,4-butanediol-d6. Grades: Highly Purified. CAS No. 104411-12-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
rac Enterolactone
A metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: (3R,4R)-rel-Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-furanone; trans-Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-Furanone; HPMF; trans-2,3-Bis(3-hydroxybenzyl)-γ-butyrolactone. Grades: Highly Purified. CAS No. 78473-71-9. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
rac Enterolactone-d6
A labelled metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Group: Biochemicals. Alternative Names: Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-furanone-d6; trans-Dihydro-3,4-bis[(3-hydroxyphenyl)methyl]-2(3H)-Furanone-d6; HPMF-d6; trans-2,3-Bis(3-hydroxybenzyl)-γ-butyrolactone-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(rac-Enterolactone)-O-glucuronide (Mixture of Diastereomers)
(rac-Enterolactone)-O-glucuronide is the oxidative metabolite of rac Enterolactone, a metabolite of sesame lignans (sesamin, sesamolin). Inhibits colonic cancer cell growth by inducing cell cycle arrest and apoptosis. Possible relationship between exposure and reduced risk of breast cancer. Synonyms: 3-[[Tetrahydro-4-[(3-hydroxyphenyl)methyl]-2-oxo-3-furanyl]methyl]phenyl-β-D-glucopyranosiduronic Acid; (2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(3-((4-(3-hydroxybenzyl)-2-oxotetrahydrofuran-3-yl)methyl)phenoxy)tetrahydro-2H-pyran-2-carboxylic Acid. CAS No. 768385-57-5. Molecular formula: C24H26O10. Mole weight: 474.46.
Sesame Seed Extract
Natural bioactive obtained from seeds of sesame (Sesamum indicum), a plant native to Ethiopia (Africa). It is a fraction rich in sesamin, which belongs to a group of compounds called lignans. Provides excellent wrinkle smoothing and lip plumping effect. Restores lost volume and minimizes appearance of lines, and the lips look fuller and smoother for a more youthful appearance. Improves skin hydration, smoothes its texture and blurs blemishes. Uses: Anti-aging creams and lotions, lip plumper products. Group: Skin actives. CAS No. 73398-61-5 / 5306-85-4 / 8008-74-0 / 59-02-9. Appearance: Clear colorless to slightly yellowish liquid. Catalog: CI-SC-0755.
sesamolin
Sesamin and sesamolin have been demonstrated to possess several bioactivities beneficial for human health. Excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells was significantly attenuated when they were pretreated with sesamin or sesamolin. The neuroprotective effect of sesamin and sesamolin was also observed in vivo using gerbils subjected to a focal cerebral ischemia induced by occlusion of the right common carotid artery and the right middle cerebral artery. Synonyms: (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; (+)-5-[(1S,3aβ,4R,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-benzodioxol-5-yloxy)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole; 5-[(1S,3aR,4R,6aR)-4-(1,3-Benzodioxol-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. Grades: >98%. CAS No. 526-07-8. Molecular formula: C20H18O7. Mole weight: 370.36.
Sesamolin
Sesaminol, isolated from Sesamum indicum, has antioxidative activity, Sesaminol inhibits lipid peroxidation and shows neuroprotection effect. Sesaminol potently inhibits MAPK cascades by preventing phosphorylation of JNK, p38 MAPKs, and caspase-3 but not ERK-MAPK expression. Group: Inhibitors. Alternative Names: 5-[(1S,3aβ,4β,6aβ)-4-(1,3-Benzodioxole-5-yloxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole. CAS No. 526-07-8. Molecular formula: C20H18O7. Mole weight: 370.36. Appearance: White powder. Purity: 0.98. IUPACName: 5-[[(3S,3aR,6R,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]oxy]-1,3-benzodioxole. Canonical SMILES: C1C2C (COC2OC3=CC4=C (C=C3)OCO4)C (O1)C5=CC6=C (C=C5)OCO6. Density: 1.418 g/ml. Catalog: ACM526078-1.
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