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1-Docosahexaenoyl-2,3-oleoyl Glycerol-d5 is labelled 1-Docosahexaenoyl-2,3-oleoyl Glycerol (D494605) which is a derivative of 1-O-alkylglycerol type, which are the the main components in liver oils of shark, and dogfish. 1-O-alkyl-sn-glycerols, are shown to have therapeutic effects on human health. They can be used for the immune control, asthma, psoriasis, arthritis or to speed up the removal of heavy metals from the body, and also as anticancer agents. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C61H101D5O4, Molecular Weight: 908.52. US Biological Life Sciences.
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Chondroitine sulfate
Chondroitin sulfate can be found in the Shark cartilage. Chondroitin is in dietary supplements used as an alternative medicine to treat osteoarthritis and also approved and regulated as a symptomatic slow-acting drug for this disease (SYSADOA) in Europe and some other countries. The hydrolysis and transglycosylation reactions of bovine testicular hyaluronidase were dose-dependently inhibited by Chondroitin sulfate oligosaccharides. Uses: Antihyperlipemic. Synonyms: poly-1(2/3)-n-acetyl-2-amino-2-deoxy-3-o-beta-d-glucopyranurosyl-4-(6)sulfonyl-d-galactose; chondroitinpolysulfate; chondroitinsulfates; chondroitinsulfuricacid; chondroitinsulfuricacids; chonsurid; CHONDROITIN SULPHATE; CHONDROITINE SULPHATE. Grades: >90%. CAS No. 9007-28-7. Molecular formula: (C14H21NO14S)n. Mole weight: 463.37.
Pardaxin P-1
Pardaxin 1 is an antimicrobial peptide found in Pardachirus pavoninus (Pacific Peacock sole, Achirus pavoninus), and has antimicrobial activity. It is used as a shark repellent and causes lysis of mammalian and bacterial cells, similar to melittin. Synonyms: Pardaxin P1; Pardaxin Pa1; Pardaxin 1; H-Gly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Glu-Gln-Glu-OH. Grades: ≥95%. Molecular formula: C157H252N36O47. Mole weight: 3395.94.
Pardaxin P-2
Pardaxin 2 is an antimicrobial peptide found in Pardachirus pavoninus (Pacific Peacock sole, Achirus pavoninus), and has antimicrobial activity. It is used as a shark repellent and causes lysis of mammalian and bacterial cells, similar to melittin. Synonyms: Pardaxin P2; Pardaxin Pa2; Pardaxin 2; H-Gly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Ile-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Gly-Gln-Glu-OH; Pardaxin P 1, 14-L-Isoleucine-31-Glycine-. Grades: ≥98%. CAS No. 104883-59-2. Molecular formula: C154H248N36O45. Mole weight: 3323.83.
Pardaxin P-3
Pardaxin 3 is an antimicrobial peptide found in Pardachirus pavoninus (Pacific Peacock sole, Achirus pavoninus), and has antimicrobial activity. It is used as a shark repellent and causes lysis of mammalian and bacterial cells, similar to melittin. Synonyms: Pardaxin P3; Pardaxin Pa3; Pardaxin 3; H-Gly-Phe-Phe-Ala-Phe-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Glu-Gln-Glu-OH; Pardaxin P 1, 5-L-Phenylalamine-. Grades: ≥96%. CAS No. 104916-49-6. Molecular formula: C160H250N36O47. Mole weight: 3429.91.
Pardaxin P-4
Pardaxin Pa4 is an antimicrobial peptide found in Pardachirus marmoratus (Rad sea moses sole flatfish, Achirus marmoratus), and has antimicrobial activity. It is used as a shark repellent and causes lysis of mammalian and bacterial cells, similar to melittin. Synonyms: Pardaxin P4; Pardaxin Pa4; Pardaxin 4; Gly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Gly-Gln-Glu; glycyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-leucyl-L-isoleucyl-L-prolyl-L-lysyl-L-isoleucyl-L-isoleucyl-L-seryl-L-seryl-L-prolyl-L-leucyl-L-phenylalanyl-L-lysyl-L-threonyl-L-leucyl-L-leucyl-L-seryl-L-alanyl-L-valyl-glycyl-L-seryl-L-alanyl-L-leucyl-L-seryl-L-seryl-L-seryl-glycyl-glycyl-L-glutaminyl-L-glutamic acid; Pardaxin P 1, 31-Glycine-. Grades: ≥97%. CAS No. 134940-98-0. Molecular formula: C154H248N36O45. Mole weight: 3323.88.
Pardaxin P-5
Pardaxin 5 is an antimicrobial peptide found in Pardachirus marmoratus (Rad sea moses sole flatfish, Achirus marmoratus), and has antimicrobial activity. It is used as a shark repellent and causes lysis of mammalian and bacterial cells, similar to melittin. Synonyms: Pardaxin P5; Pardaxin Pa5; Pardaxin 5; Gly-Phe-Phe-Ala-Leu-Ile-Pro-Lys-Ile-Ile-Ser-Ser-Pro-Leu-Phe-Lys-Thr-Leu-Leu-Ser-Ala-Val-Gly-Ser-Ala-Leu-Ser-Ser-Ser-Gly-Asp-Gln-Glu. Grades: ≥96%. Molecular formula: C156H250N36O47. Mole weight: 3381.91.
Pristane
Pristane is a natural product from shark liver oil and a non-antigenic adjuvant. Group: Heterocyclic organic compound. Alternative Names: 2,6,10,14-Tetramethylpentadecane pristane. CAS No. 1921-70-6. Molecular formula: C19H40. Mole weight: 268.5. Appearance: liquid. Purity: 95%+. IUPACName: 2,6,10,14-Tetramethylpentadecane. Canonical SMILES: CC(C)CCCC(C)CCCC(C)CCCC(C)C. Density: 0.783 g/mL at 20 °C (lit.). ECNumber: 217-650-8. Catalog: ACM1921706.
Scyliorhinin i(9ci)
Heterocyclic Organic Compound. Alternative Names: SHARK SUBSTANCE P RELATED PEPTIDE;SCY 1;SCYLIORHININ I;SCYLIORHININ I AMIDE (DOGFISH);ALA-LYS-PHE-ASP-LYS-PHE-TYR-GLY-LEU-MET-NH2;AKFDKFYGLM;H-ALA-LYS-PHE-ASP-LYS-PHE-TYR-GLY-LEU-MET-NH2;H-ALA-LYS-PHE-ASP-LYS-PHE-TYR-GLY-LEU-MET-OH. CAS No. 103425-21-4. Molecular formula: C59H87N13O13S. Mole weight: 1218.47. Purity: 0.96. IUPACName: (3S)-4-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]a. Canonical SMILES: CC (C)CC (C (=O)NC (CCSC)C (=O)N)NC (=O)CNC (=O)C (CC1=CC=C (C=C1)O)NC (=O)C (CC2=CC=CC=C2)NC (=O)C (CCCCN)NC (=O)C (CC (=O)O)NC (=O)C (CC3=CC=CC=C3)NC (=O)C (CCCCN)NC (=O)C (C)N. Density: 1.264 g/cm³. Catalog: ACM103425214.
scymnol sulfotransferase
The enzyme from the shark Heterodontus portusjacksoni is able to sulfate the C27 bile salts 5β-scymnol (the natural bile salt) and 5α-cyprinol (the carp bile salt). Enzyme activity is activated by Mg2+ but inhibited by the product 5β-scymnol sulfate. Group: Enzymes. Enzyme Commission Number: EC 2.8.2.32. CAS No. 220581-70-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3392; scymnol sulfotransferase; EC 2.8.2.32; 220581-70-4. Cat No: EXWM-3392.
sodium hyaluronate
The PhEur describes sodium hyaluronate as the sodium salt of hyaluronic acid, a glycosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units. Sodium hyaluronate occurs as white to off-white powder or granules. It is very hygroscopic. Synonyms: Hyaluronan; hyaluronate sodium; natrii hyaluronas; RITA HA C1-C. CAS No. 9067-32-7. Product ID: PE-0674. Molecular formula: (C14H20NO11Na)n. Mole weight: (401.3)n. Category: Humectant; lubricant; sustained-release agent. Product Keywords: Humectants Excipients; PE-0674; sodium hyaluronate; 9067-32-7; Hyaluronan; hyaluronate sodium; natrii hyaluronas; RITA HA C1-C. Chemical Name: Sodium hyaluronate. Grade: Pharmaceutical grade. Administration route: Topical gel. preparation. Dosage Form: Topical gel. preparation. Stability and Storage Conditions: Sodium hyaluronate should be stored in a cool, dry place in tightly sealed containers. The powder is stable for 3 years if stored in unopened containers. Source and Preparation: Sodium hyaluronate occurs naturally in vitreous humor, serum,chicken combs, shark skin, and whale cartilage; it is usually extracted and purified from chicken combs. It may also be manufactured by fermentation of selected Streptococcus zooepidemicus bacterial strains; sodium hyaluronate is removed from the fermentation medium by filtration and purified by ultrafiltration. It is then precipitated with an organic solvent and
Squalamine
Squalamine is a naturally derived broad-spectrum antibiotic that is predominantly derived from the livers of dogfish and other shark species. Squalamine is undergoing trials for treatment of non-small cell lung cancer (stage I/IIA) as well as general phase I pharmacokinetic studies. In 2005, the Food and Drug Administration granted squalamine Fast Track status for approval for treatment of age-related macular degeneration. However, the Genaera Corporation, the company that has done the most work with squalamine, discontinued trials for its use in treating prostate cancer and wet age-related macular degeneration in 2007. The Squalamine project was acquired by Ohr Pharmaceutical from the now liquidated Genaera, with the prospect of continuing the development of this drug to treat wet age-related macular degeneration. Synonyms: MSI 1256; MSI-1256; MSI1256. Grades: ≥98% (HPLC). CAS No. 148717-90-2. Molecular formula: C34H65N3O5S. Mole weight: 627.96.
Squalamine lactate
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark. Group: Marine natural products. Alternative Names: Evizon. CAS No. 320725-47-1. Mole weight: 718. Purity: 95%+. IUPACName: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate;(2S)-2-hydroxypropanoic acid. Canonical SMILES: CC (C)C (CCC (C)C1CCC2C1 (CCC3C2C (CC4C3 (CCC (C4)NCCCNCCCCN)C)O)C)OS (=O) (=O)O. CC (C (=O)O)O. Catalog: ACM320725471.
Squalamine lactate
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Group: Natural products. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467.
Squalane
Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 111-01-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N7113.
Trimethylamine N-oxide
TMAO (TMAO) is the organic compound in the class of amine oxides with the formula (CH3)3NO. This colorless solid is usually encountered as the dihydrate. It is a product of the oxidation of trimethylamine and a common metabolite in animals. It is an osmolyte found in saltwater fish, sharks, rays, molluscs, and crustaceans. It is a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays. It is also higher in deep-sea fishes and crustaceans, where it may counteract the protein-destabilizing effects of pressure. TMAO decomposes to trimethylamine (TMA), which is the main odorant that is characteristic of degrading seafood. Group: Heterocyclic organic compound. Alternative Names: Trimethyloxamine. CAS No. 1184-78-7. Molecular formula: C3H9NO. Mole weight: 75.11. Appearance: Pale yellow solid. Purity: 0.95. IUPACName: N,N-Dimethylmethanamine oxide. Canonical SMILES: C[N+](C)(C)[O-]. Density: 0.9301 g/cm³. ECNumber: 214-675-6. Catalog: ACM1184787.
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