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| Product | Description | |
|---|---|---|
| Cytoskeletal Signaling Pathway Compound Library | A unique collection of 590 cytoskeleton-related compounds, can be used for HTS and HCS?. Uses: Scientific use. Product Category: L1310. Categories: Cytoskeletal Signaling Pathway Compounds Libraries. |  |
| Hedgehog (Hh) Signaling Pathway Antagonist (N-[4-Chloro-3- (trifluoromethyl) phenyl]-N-[[3- (4-fluorophenyl) -3, 4-dihydro-4-oxo-2-quinazolinyl]methyl-urea) | Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC50 = 70nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 330796-24-2. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| HIF-1 Signaling Pathway Compound Library | A unique collection of 1352 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies?- Covers PI3K-AKT, MAPK, Ubiquitination signaling pathways and targets such as HIF, HIF Prolyl-Hydroxylase, E1/E2/E3 Enzyme, PI3K, MAPK, Proteasome, etc. - Part of them are in clinical trial phase or FDA approved?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L8500. Categories: HIF-1 Signaling Pathway Compounds Libraries. | |
| 10058-F4 | 10058-F4 is a c-Myc inhibitor that prevents c-Myc-Max dimerization and transactivation of c-Myc target gene expression. Uses: Scientific research. Group: Signaling pathways. CAS No. 403811-55-2. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-12702. |  |
| 10-DEBC hydrochloride | 10-DEBC hydrochloride is a selective Akt inhibitor, with an IC 50 of 1.28 μM. 10-DEBC hydrochloride is a novel anti-TB compound [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 925681-41-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100654. | |
| 10-Gingerol | 10-Gingerol is an AMPK agonist, which is found in the ginger oleoresin from fresh rhizome with anti-inflammatory, antioxidant and anti-proliferative activities. 10-Gingerol suppresses neointimal hyperplasia and inhibits vascular smooth muscle cell proliferation. 10-Gingerol exhibits substantial scavenging activities with an IC 50 value of 10.47 μM against DPPH radical, an IC 50 value of 1.68 μM against superoxide radical and an IC 50 value of 1.35 μM against hydroxyl radical. 10-Gingerol inhibits the proliferation of MDA-MB-231 tumor cell line with an IC 50 of 12.1 μM. 10-Gingerol suppresses the proliferation, migration, invasion, and induced apoptosis through targeting the PI3K/Akt signaling pathway in MDA-MB-231/IR cells. 10-Gingerol is promising for research of ulcerative colitis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 23513-15-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0448. | |
| 10-Hydroxy-12(Z)-octadecenoic acid | 10-Hydroxy-12(Z)-octadecenoic acid is an ester product. Uses: Scientific research. Group: Signaling pathways. CAS No. 34932-12-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-165772. | |
| 10-Nitrolinoleic acid | 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [ 3 H]Rosiglitazone for binding to PPAR-γ, with an IC 50 of 0.22 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 774603-04-2. Pack Sizes: 100 μg (3.07 mM * 100 μL in Ethanol). Product ID: HY-113473. | |
| 10-Oxo-12(Z)-octadecenoic acid | 10-Oxo-12(Z)-octadecenoic acid is an ester product. Uses: Scientific research. Group: Signaling pathways. CAS No. 103521-29-5. Pack Sizes: 100 μg; 500 μg. Product ID: HY-165810. | |
| 10-Undecen-1-ol | 10-Undecen-1-ol, converted from ricinoleic acid, can be used as a comonomer for the introduction of functional groups [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112-43-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W004298. | |
| 10(Z)-Pentadecenoic acid | 10(Z)-Pentadecenoic acid is an unsaturated fatty acid. Unsaturated fatty acids are an important class of lipid molecules whose chemical structure contains one or more double bonds. Uses: Scientific research. Group: Signaling pathways. Alternative Names: cis-10-Pentadecenoic acid. CAS No. 84743-29-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120996B. | |
| (±)11(12)-EET | (±)11(12)-EET is a NLRP3 inflammasome inhibitor. (±)11(12)-EET can be used for the research of anti-inflammatory, angiogenic and cardioprotective [1] [2] [3] [4] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 11,12-EET. CAS No. 87173-81-7. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-130494. | |
| 11alpha-Hydroxyprogesterone | 11alpha-Hydroxyprogesterone is the analogue of 11beta-Hydroxyprogesterone (HY-N2337), and can be used as an experimental control. 11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase ; also activates human mineralocorticoid receptor in COS-7 cells with an ED 50 of 10 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 80-75-1. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W011243. | |
| 11-Aminoundecanoic acid | 11-Aminoundecanoic acid is an alkyl chain based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2432-99-7. Pack Sizes: 10 g. Product ID: HY-W014831. | |
| 1,1'-Binaphthyl-2,2'-diamine | 1,1'-Binaphthyl-2,2'-diamine is the isomer of (S)-[1, 1'-Binaphthalene]-2, 2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1, 1'-Binaphthalene]-2, 2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,2'-Diamino-1,1'-dinaphthyl. CAS No. 4488-22-6. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W007978B. | |
| 11-Deoxy Prostaglandin E2 | 11-Deoxy Prostaglandin E2 is a selective agonist of EP4 with an EC 50 of 0.66 nM. 11-Deoxy Prostaglandin E2 is an analog of prostaglandin E2. 11-Deoxy Prostaglandin E2 can be used in study bone healing, heart failure, and other receptor associated conditions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35536-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114910. | |
| 1,1-Dimethoxyacetone | Pyruvic aldehyde dimethyl acetal is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 6342-56-9. Pack Sizes: 100 g; 500 g. Product ID: HY-Y0872. | |
| 11-Ketotestosterone | 11-Ketotestosterone (11-Oxotestosterone), an oxidized form of Testosterone, is an active androgen [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 11-Oxotestosterone. CAS No. 564-35-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-114612. | |
| 1,2,3,4-Tetramethylbenzene | 1,2,3,4-Tetramethylbenzene consists of a benzene ring with four methyl groups (-CH 3 ) as a substituent. 1,2,3,4-Tetramethylbenzene is a specialty product for biochemistry research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 488-23-3. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W006416. | |
| 1-(2,3-Dichlorphenyl)piperazine hydrochloride | 1-(2,3-Dichlorphenyl)piperazine hydrochloride is a potent DHCR7 inhibitor with the activity of inhibiting cholesterol biosynthesis. 1-(2,3-Dichlorphenyl)piperazine hydrochloride is often used in biological research to evaluate the function of cholesterol biosynthesis pathway. The application of 1-(2,3-Dichlorphenyl)piperazine hydrochloride is of great significance for understanding diseases related to cholesterol biosynthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119532-26-2. Pack Sizes: 10 mM * 1 mL; 50 g; 100 g. Product ID: HY-Y0889A. | |
| 1,2,3-Trimethoxybenzene | 1,2,3-Trimethoxybenzene is a member of the class of compounds known as anisoles. 1,2,3-Trimethoxybenzene can be found in tea, which makes 1,2,3-trimethoxybenzene a potential biomarker for the consumption of this food product. Uses: Scientific research. Group: Signaling pathways. CAS No. 634-36-6. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-W017092. | |
| 1,2:5,6-Di-O-isopropylidene-3,4-di-O-benzyl-D-myo-inositol | 1,2:5,6-Di-O-isopropylidene-3,4-di-O-benzyl-D-myo-inositol, a chemical compound indispensable in various syntheses of inositol phosphates, exhibits profound implications in cell signaling pathways, making it a promising candidate for cancer therapy and other diseases. With its intricate chemical structure and diverse molecular properties, it imbues the inositol phosphates with their unique functionalities. Molecular formula: C26H32O6. Mole weight: 440.53. |  |
| 1,2-Bis(2-iodoethoxy)ethane | 1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker. 1,2-Bis(2-iodoethoxy)ethane can be used in the synthesis of MT802 (HY-122562) and SJF620 (HY-133137). MT-802 and SJF620 are potent PROTAC BTK degraders with DC 50 s of 1 nM and 7.9 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36839-55-1. Pack Sizes: 1 g. Product ID: HY-133143. | |
| 1,2-Bis(maleimido)ethane | 1,2-Bis(maleimido)ethane (N,N'-Ethylenedimaleimide) is a protein cross-linking agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N,N'-Ethylenedimaleimide. CAS No. 5132-30-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W013538. | |
| 1,2-Dilinoleoyl-sn-glycerol | 1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (HY-N0729) (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy. Uses: Scientific research. Group: Signaling pathways. CAS No. 24529-89-3. Pack Sizes: 5 mg (16.21 mM * 500 μL in Acetonitrile); 10 mg (16.21 mM * 1 mL in Acetonitrile). Product ID: HY-117168. | |
| 1,2-Dioleoyl-3-arachidoylglycerol | 1,2-Dioleoyl-3-arachidoylglycerol (AOO) is a triacylglycerol that can be isolated from soybean oil [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77145-65-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-157739. | |
| 1,2-Dipalmitoyl-L-alpha-phosphatidyl-D-myo-inositol 4,5-bisphosphate | 1,2-Dipalmitoyl-L-alpha-phosphatidyl-D-myo-inositol 4,5-bisphosphate is a critical component in signaling pathways. Group: Biochemicals. Grades: Highly Purified. CAS No. 120595-88-2. Pack Sizes: 100ug, 250ug. Molecular Formula: C41H81O19P3, Molecular Weight: 970.99. US Biological Life Sciences. | Worldwide |
| 1,2-Dipalmitoyl phosphatidylinositol 4-phosphate ammonium salt | 1,2-Dipalmitoyl phosphatidylinositol 4-phosphate ammonium salt, a vital phospholipid derivative in signaling pathways associated with immune response and inflammation. This molecule has a multifaceted role, demonstrated by its ability to alter TNF-α activity and regulate T cell activation. Its therapeutic potential extends to autoimmune and inflammatory afflictions; hence, creating an opportunity to target treatments for arthritis and asthma. Synonyms: L-a-Phosphatidyl-(12-dipalmitoyl)-D-myo-inositol 4-monophosphate. CAS No. 57606-15-2. Molecular formula: C41H80O16P2. Mole weight: 891.01. | |
| 1,2-Dipalmitoyl phosphatidylinositol 5-phosphate | 1,2-Dipalmitoyl phosphatidylinositol 5-phosphate is a pivotal phospholipid, involving in intricate signaling pathways governing diverse cellular mechanisms.Its research applications encompass the exploration of lipid metabolism, membrane trafficking, and dynamic cell membrane characteristics. Synonyms: 1,2-dipalmitoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate); [ (2R) -2-hexadecanoyloxy-3- [hydroxy- [ (1R, 2R, 3R, 4R, 5S, 6R) -2, 3, 4, 6-tetrahydroxy-5-phosphonooxycyclohexyl] oxyphosphoryl] oxypropyl] hexadecanoate; L-alpha-Phosphatidyl-D-myo-inositol 5-monophosphate, dipalmitoyl; PtdIns(5)P; 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate); PtdIns(5)P1; D-myo-PI[5]P; PI5P; PI[5]P;D-myo-Phosphatidylinositol 5-phosphate (PtdIns(5)P); Q27158617; D-myo-Inositol 5-monophosphate, L- alpha -Phosphatidyl-(1,2-dipalmitoyl); D-myo-Inositol 5-monophosphate, L-alpha-Phosphatidyl-(1,2-dipalmitoyl). CAS No. 291527-75-8. Molecular formula: C41H80O16P2. Mole weight: 891.01. | |
| 12-HETE | 12-HETE, a major metabolic product of arachidonic acid using 12-LOX catalysis, inhibits cell apoptosis in a dose-dependent manner. 12-HETE promotes the activation and nuclear translocation of NF-κB through the integrin-linked kinase (ILK) pathway [1].12-HETE has both anti-thrombotic and pro-thrombotic effects [2]. 12-HETE is a neuromodulator [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71030-37-0. Pack Sizes: 50 μg (312.04 μM * 0.5 mL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113439. | |
| 1,2-Hexadecanediol | 1,2-Hexadecanediol is a reducing agent. 1,2-Hexadecanediol facilitates the decomposition of the metal-organic precursor, forms an intermediate Co 2+ Fe 3+ -oleate complex [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6920-24-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W011816. | |
| 12-Hydroxyjasmonic acid | 12-Hydroxyjasmonic acidis is a COI1-JAZ-independent activator of leaf-closing movement in Samanea saman [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-12-Hydroxyjasmonic acid. CAS No. 140631-27-2. Pack Sizes: 1 mg. Product ID: HY-N1033. | |
| 1,2-O-Dioctadecyl-sn-glycerol | 1,2-O-Dioctadecyl-sn-glycerol (Compound 7b) is a lipid molecule that can be used to synthesize thermostable lipid nanoparticle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82188-61-2. Pack Sizes: 100 mg. Product ID: HY-157524. | |
| 12-Oxo phytodienoic acid | 12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in LPS-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 12-OPDA. CAS No. 85551-10-6. Pack Sizes: 100 μg (3.42 mM * 100 μL in Ethanol). Product ID: HY-118828. | |
| 1-(2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetra hydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | (2R,3R,4R,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, commonly referred to as HMTP, is a remarkable biomedicine renowned for its multifaceted pharmacological properties. With a remarkable chemical composition, it exhibits profound efficacy against a plethora of drugs and diseases. Employing a mechanism that selectively targets crucial signaling pathways or receptors, HMTP exerts its therapeutic effects by effectively inhibiting their functions. | |
| 12(R)-HETE | 12(R)-HETE is a metabolite of Arachidonic acid, AA (HY-109590) and can be found in skin from psoriatic lesions. 12(R)-HETE induces lymphocytes chemotaxis, stimulates calcium mobilization and chemotaxis in neutrophils via the BLT1 receptor, activates the aryl hydrocarbon receptor, and inhibits Na+/K+ ATPase activity in the corneal epithelium [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82337-46-0. Pack Sizes: 5 μg (312.04 μM * 50 μL in Ethanol); 10 μg (312.04 μM * 100 μL in Ethanol); 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-124404. | |
| 13,14-Dihydro-15-keto-PGE2 | 13,14-Dihydro-15-keto-PGE2 participates in Bifidobacterium animalis F1-7 to alleviate opioid-induced constipation by 5-HT pathway [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 363-23-5. Pack Sizes: 1 mg (28.37 mM * 100 μL in Methyl acetate). Product ID: HY-113254. | |
| 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-iodo-a-D-glucopyranose | 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-iodo-α-D-glucopyranose, a pivotal compound extensively employed in the biomedical sector, exhibits remarkable structural attributes. It finds widespread application in the fabrication of groundbreaking medicinal compounds. The iodine substitution within this compound enables its utilization as an indispensable radiolabeling agent, facilitating cutting-edge diagnostic imaging practices. Moreover, it assumes a crucial role in investigating the intricate mechanisms underlying carbohydrate metabolism and the cell signaling pathways implicated in diverse pathological conditions. Synonyms: 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-iodo-D-glucopyranose; 2-DEOXY-2-IODO-1,3,4,6-TETRA-O-ACETYL--D-GLUCOPYRANOSE; [(2R,3R,4S,5R)-3,4,6-triacetyloxy-5-iodooxan-2-yl]methyl acetate; SCHEMBL14376661; DTXSID00723500. CAS No. 95672-63-2. Molecular formula: C14H19IO9. Mole weight: 458.20. | |
| 1,3,5-Trimethylpyrazole | 1,3,5-Trimethylpyrazole is a compound used for chemical synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1072-91-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N7086. | |
| 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22224-41-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W013728. | |
| 1,3-Dibromo-5,5-dimethylhydantoin | 1,3-Dibromo-5,5-dimethylhydantoin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77-48-5. Pack Sizes: 500 g. Product ID: HY-Y0786. | |
| 1,3-Dicyclohexylurea | 1,3-Dicyclohexylurea (DCU) is an orally active and potent sEH (soluble epoxide hydrolase) inhibitor. Oral Delivery of 1,3-Dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive Rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387-23-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 500 mg. Product ID: HY-W013989. | |
| 1,3-Diphenylguanidine | 1,3-diphenylguanidine is the primary and secondary accelerator in the vulcanization of rubber and is found in the rubber industry [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 102-06-7. Pack Sizes: 10 mM * 1 mL; 100 g; 500 g. Product ID: HY-W014332. | |
| 13(E)-Docosenoic acid | 13(E)-Docosenoic acid (Brassidic acid), a trans-acid, is a 22-carbon monounsaturated fatty acid [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Brassidic acid; trans-13-Docosenoic acid. CAS No. 506-33-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-116739. | |
| 1,3-Propanesultam | 1,3-Propanesultam (1,1-Dioxoisothiazolidine) is a bioactive chemical, and can be used for the synthesis of active compound [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,1-Dioxoisothiazolidine. CAS No. 5908-62-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-W001194. | |
| 1400W Dihydrochloride | 1400W dihydrochloride is the dihydrochloride form of 1400W (HY-18730). 1400W is a slow, tight binding, and highly selective inducible nitric-oxide synthase ( iNOS ) inhibitor, with a K d value ≤ 7 nM. 1400W inhibits iNOS induction in microglial cells, and reduces generation of NO, thereby mitigating oxidative stress and neuronal cell apoptosis in the rat cerebral cortex, and improving the spatial memory dysfunction caused by acute hypobaric hypoxia-reoxygenation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 214358-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18731. | |
| 14-3-3η Protein inhibitor 1 | 14-3-3η Protein inhibitor 1 (Compound C11) is a 14-3-3η protein inhibitor with a K D of 35 μM. 14-3-3η Protein inhibitor 1 shows inhibitory activities against several typical human liver cancer cell lines. 14-3-3η Protein inhibitor 1 induces cell apoptosis and G1-S cell cycle arrest with good metabolic stability [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2770842-10-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146302. | |
| 1,4,7-Triazonane | 1,4,7-Triazonane (1,4,7-Triazacyclononane), an intermediate in the synthesis of 1,4,7-trifunctionalized derivatives, is a possible reagent for compleximetric titrations with high cation-binding selectivity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,4,7-Triazacyclononane. CAS No. 4730-54-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W006212. | |
| 1,4-Anthraquinone | 1,4-Anthraquinone is a potent anticancer agent. 1,4-Anthraquinone blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of cancer cells. 1,4-Anthraquinone can be used to research anti-leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 635-12-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W077242. | |
| 1,4-Cyclohexanedione | 1,4-Cyclohexanedione is a biological material or organic compound that can be used in life science research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 637-88-7. Pack Sizes: 25 g. Product ID: HY-W010554. | |
| 1,4-Dichlorobenzene | 1,4-Dichlorobenzene is used as an intermediate product in the manufacture of pigments, pesticides and disinfectants. 1,4-Dichlorobenzene is also employed as a moth control agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106-46-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0496. | |
| 1,4-Naphthoquinone | 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130-15-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W015490. | |
| 14(S)-HDHA | 14(S)-HDHA (14(S)-HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA). 14(S)-HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 14(S)-HDoHE. CAS No. 119433-37-3. Pack Sizes: 25 μg (290.28 μM * 250 μL in Ethanol). Product ID: HY-130239. | |
| 1,5,5-Trimethylhydantoin | 1,5,5-Trimethylhydantoin (TMH) is a non-isotopic internal standard (IS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMH. CAS No. 6851-81-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W012606. | |
| 1-(5-Carboxypentyl)-2,3,3-trimethyl-3H-indol-1-ium-5-sulfonate | 1-(5-Carboxypentyl)-2,3,3-trimethyl-3H-indol-1-ium-5-sulfonate, a highly sought-after fluorescent probe, has gained immense popularity in biomedical research due to its ability to detect minute cellular anomalies associated with cancer and other life-threatening diseases. Its application extends beyond its diagnostic potential and is frequently utilized in drug discovery initiatives aimed at identifying novel therapeutics that target specific and often elusive signaling pathways involved in disease progression. Its remarkable attributes and versatility have made it an indispensable tool in the ever-expanding realm of medical research. Synonyms: 1-(5-carboxypentyl)-2,3,3-trimethyl-3H-indolium-5-sulfonate (IM OCS). CAS No. 146368-08-3. Molecular formula: C17H23NO5S. Mole weight: 353.4. | |
| 15-deoxy-Δ12,14-Prostaglandin D2 | 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2), a metabolite of PGD2 (HY-101988), is an agonist of prostaglandin receptor 2 (DP2). 15-deoxy-Δ12,14-Prostaglandin D2 binds to DP2 (Ki=50 nM) and induces eosinophil activation ( EC 50 =8 nM). 15-deoxy-Δ12,14-Prostaglandin D2 also stimulates the recruitment of steroid receptor coactivator-1 ( SRC-1 ) to peroxisome proliferator-activated receptor γ ( PPARγ ), inducing PPARγ-mediated transcription. 15-deoxy-Δ12,14-Prostaglandin D2 (15-Deoxy-Δ12,14-PGD2) is cytotoxic to L1210 murine leukemia cells ( IC 50 =0.3 μg/ml) and inhibits ADP-induced platelet aggregation ( IC 50 =320 ng/mL). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15-Deoxy-Δ12,14-PGD2. CAS No. 85235-11-6. Pack Sizes: 1 mg (2.99 mM * 1 mL in Methyl acetate). Product ID: HY-116028. | |
| 15-Keto Travoprost | 15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15-Keto Fluprostenol isopropyl ester. CAS No. 404830-45-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-116617. | |
| 15(R)-HETE | 15(R)-HETE is an isomer of 15-HETE. 15-HETE is a lipid mediator derived from arachidonic acid and can be used for the study of asthma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83603-31-0. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-113336A. | |
| 15(S)-HEPE | 15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA. CAS No. 86282-92-0. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol); 50 μg (314.02 μM * 500 μL in Ethanol). Product ID: HY-130675A. | |
| 15(S)-HPETE | 15(S)-HPETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A41 or reduced to 15(S)-HETE by peroxidases.2,1 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1.3 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inactivation of porcine 12-LO. Uses: Scientific research. Group: Signaling pathways. CAS No. 70981-96-3. Pack Sizes: 25 μg (297.20 μM * 250 μL in Ethanol). Product ID: HY-113438. | |
| 16,16-Dimethyl prostaglandin E2 | 16,16-Dimethyl prostaglandin E2 (16,16-dimethyl PGE2) is an orally active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator. 16,16-Dimethyl prostaglandin E2 can act through EP2/EP4 and has an interaction with the Wnt pathway [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 16,16-dimethyl PGE2. CAS No. 39746-25-3. Pack Sizes: 5 mg (26.28 mM * 500 μL in Methyl acetate); 10 mg (26.28 mM * 1 mL in Methyl acetate); 25 mg (26.28 mM * 2.5 mL in Methyl acetate); 50 mg (26.28 mM * 5 mL in Methyl acetate); 100 mg (26.28 mM * 10 mL in Methyl acetate). Product ID: HY-106420. | |
| 16α-Hydroxyprednisolone | 16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OH-PRED. CAS No. 13951-70-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-117580. | |
| 16-Azidohexadecanoic acid | 16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism [1] [2]. 16-Azidohexadecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 112668-54-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147309. | |
| 16-Hydroxyhexadecanoic acid | 16-Hydroxyhexadecanoic acid (Juniperic acid) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Juniperic acid. CAS No. 506-13-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W068212. | |
| 17β-Estradiol sulfate sodium | 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17β-Estradiol 3-sulfate sodium. CAS No. 4999-79-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141672. | |
| 17-HDHA | 17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27 + CD38 + antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90780-52-2. Pack Sizes: 25 μg (290.28 μM * 250 μL in Ethanol); 50 μg (290.28 μM * 500 μL in Ethanol); 100 μg (290.28 μM * 1 mL in Ethanol). Product ID: HY-113512. | |
| 17-ODYA | 17-ODYA is a CYP450 ω-hydroxylase inhibitor. 17-ODYA is also a potent inhibitor (IC 50 <100 nM) of the formation of 20-hydroxyeicosatetraenoic acid (20-HETE), epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids by rat renal cortical microsomes incubated with arachidonic acid. 17-ODYA completely attenuates the isoproterenol (ISO)-induced apoptosis, and necrosis in cultured cardiomyocytes [1] [2] [3]. 17-ODYA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 34450-18-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101016. | |
| 17-Phenyl trinor PGF2α isopropyl ester | 17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost.1 The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost.2 This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP receptor agonist.3 In human and animal models of glaucoma, FP receptor agonist activity corresponds very closely with intraocular hypotensive activity. The 17-phenyl trinor PGF2α isopropyl ester derivative is examined for IOP-lowering activity during the development of latanoprost.4 At the dose of 3 μg/eye in the monkey, 17-phenyl trinor PGF2α isopropyl ester is the most potent analog tested in reducing IOP, lowering the IOP 1.3 mm Hg below the level achieved by latanoprost. However, this derivative is also significantly more irritating to the eye than latanoprost. Uses: Scientific research. Group: Signaling pathways. CAS No. 130209-76-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116161A. | |
| 17-Phenyl-trinor-prostaglandin E2 | 17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2). Group: Biochemicals. Grades: Highly Purified. CAS No. 38315-43-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H30O5, Molecular Weight: 386.48. US Biological Life Sciences. | Worldwide |
| (17R,18S)-Epoxyeicosatetraenoic acid | (17R,18S)-Epoxyeicosatetraenoic acid (17(R),18(S)-EETeTr) is a cytochrome P450 epoxygenase metabolite of eicosapentaenoic acid (HY-B0660). (17R,18S)-Epoxyeicosatetraenoic acid shows exerts negative chronotropic effects and protects neonatal rat cardiomyocytes against Ca 2+ overload. (17R,18S)-Epoxyeicosatetraenoic acid has the potential for the research of antiarrhythmic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17(R),18(S)-EETeTr. CAS No. 725246-18-4. Pack Sizes: 25 μg (314.02 μM * 250 μL in Ethanol). Product ID: HY-113040A. | |
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