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A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2,2-Dimethylbutanoic Acid (1S,7S,8S,8aR)-1,2,3,7,8,8a- Hexahydro-7-methyl-3-methylene-8-[2-[(2R,4R)-tetrahydro -4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester; 6'-Exomethylene Simvastatin. Grades: > 95%. CAS No. 121624-18-8. Molecular formula: C25H36O5. Mole weight: 416.56.
Simvastatin Impurity H
Cas No. 79952-42-4.
Simvastatin impurity K
Simvastatin impurity K. Group: Biochemicals. Alternative Names: 4a,5-Dihydro simvastatin. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Simvastatin Impurity K
Simvastatin Impurity K (4alpha,5-Dihydro Simvastatin)
4alpha,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin, a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Alternative Names: (1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate; Simvastatin Impurity K. Grades: Highly Purified. Pack Sizes: 500ug, 1mg, 5mg. Molecular Formula: C25H40O5. US Biological Life Sciences.
Worldwide
3-Methylene Simvastatin Impurity
3-Methylene Simvastatin Impurity. Group: Biochemicals. Alternative Names: [1S-[1α,3α,7 β,8 β(2S*,4S*),8a β]]-2,2,3-Trimethyl-3-butenoic Acid 1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; Simvastatin Impurity G. Grades: Highly Purified. CAS No. 79902-62-8. Pack Sizes: 5mg. Molecular Formula: C26H38O5, Molecular Weight: 430.58. US Biological Life Sciences.
Worldwide
Simvastatin Dimer Impurity
An impurity of Simvastatin (Dimer). Group: Biochemicals. Alternative Names: Simvastatin Impurity D. Grades: Highly Purified. CAS No. 476305-24-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Simvastatin EP Impurity A Ammonium Salt
Simvastatin EP Impurity A Ammonium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 139893-43-9. Molecular formula: C25H43NO6. Mole weight: 453.62. Catalog: APB139893439.
Simvastatin EP impurity A (calcium salt)
Simvastatin EP impurity A (calcium salt). Uses: For analytical and research use. Group: Impurity standards. CAS No. 151006-18-7. Molecular formula: C25H42CaO6. Mole weight: 478.68. Catalog: APB151006187.
Simvastatin EP Impurity A Sodium Salt
Simvastatin EP Impurity A Sodium Salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 101314-97-0. Molecular formula: C25H39NaO6. Mole weight: 458.57. Catalog: APB101314970.
Simvastatin EP Impurity B
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Acetyl simvastatin; 4'-Acetyl Simvastatin; Simvastatin Acetate; Simvastatin acetate ester; Simvastatin USP Related Compound B. Grades: 95%. CAS No. 145576-25-6. Molecular formula: C27H40O6. Mole weight: 460.62.
Simvastatin EP Impurity C
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Simvastatin USP Related Compound C; 2,3-Anhydro Simvastatin; Dehydro Simvastatin; Anhydro simvastatin. Grades: 95%. CAS No. 210980-68-0. Molecular formula: C25H36O4. Mole weight: 400.56.
Simvastatin EP Impurity F
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Simvastatin USP Related Compound F; epi-Lovastatin; Lovastatin epimer; (2R)-2-Methylbutanoic Acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Grades: 95%. CAS No. 79952-44-6. Molecular formula: C24H36O5. Mole weight: 404.55.
Simvastatin EP Impurity I
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2'-Ethyl Simvastatin. CAS No. 79902-42-4. Molecular formula: C23H34O5. Mole weight: 390.51.
Simvastatin EP Impurity N
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Methylsimvastatin; 5-Methylsimvastatin; 2-Methyl Simvastatin (Mixture Of Diasteroisomers); 2,2-Dimethyl-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester Butanoic Acid. CAS No. 774611-54-0. Molecular formula: C26H40O5. Mole weight: 432.59.
1, 5-Cyclooctadiene (pyridine) (tri cyclohexylphosphine) iridium (I) Hexafluorophosphate is a catalyst that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 64536-78-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C31H48F6IrNP2. US Biological Life Sciences.
Worldwide
2,2-Dimethylbutanoyl Chloride
2,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin (D450010). 4α,5-Dihydro Simvastatin is an impurity in the synthesis of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 5856-77-9. Pack Sizes: 1g, 5g. Molecular Formula: C6H11ClO. US Biological Life Sciences.
Worldwide
2-Desethyl-2-vinyl Dehydrosimvastatin
2-Desethyl-2-vinyl Dehydrosimvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C25H34O4. US Biological Life Sciences.
2-Desethyl-2-vinyl t-Butyldimethylsilyl Simvastatin is an intermediate in synthesizing 2-Desethyl-2-vinyl Simvastatin (D289830), a Simvastatin (S485000) impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 79902-58-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C31H50O5Si. US Biological Life Sciences.
Worldwide
2'-Ethyl Simvastatin
2'-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. CAS No. 79902-42-4. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H34O5, Molecular Weight: 390.51. US Biological Life Sciences.
Worldwide
2'-Ethyl Simvastatin-d6
Isotope labelled 2'-Ethyl Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. Simvastatin, the drug, is sold under the trade name Zocor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28D6O5, Molecular Weight: 396.55. US Biological Life Sciences.
Worldwide
2-Methyl Simvastatin (Mixture Of Diasteroisomers)
2-Methyl Simvastatin is an impurity of Simvastatin, a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Grades: Highly Purified. CAS No. 774611-54-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C26H40O5. US Biological Life Sciences.
Worldwide
3,4-Epoxy-6-keto-4a,5-ene Simvastatin
3,4-Epoxy-6-keto-4A,6-ene Simvastatin is an impurity of Simvastatin (S485000), a synthetic derivative of a fermentation product of Aspergillus terreus and a competitive inhibitor of HMG-CoA reductase. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
3-?[[ (4-?Methylphenyl) ?sulfonyl]?oxy]?-butanoic Acid Ethyl Ester is an intermediate in synthesizing 2-Desethyl-2-vinyl Simvastatin (D289830), a Simvastatin (S485000) impurity. Group: Biochemicals. Grades: Highly Purified. CAS No. 316148-56-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C15H22O5S. US Biological Life Sciences.
Worldwide
3-Hydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?7,?8,?8a-hexahydro-3-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 134523-09-4. Molecular formula: C25H38O6. Mole weight: 434.57.
3-Hydroxy Simvastatin Acid, Sodium Salt
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 3"-Hydroxy Simvastatin Acid Sodium Salt; 3-Hydroxy Simvastatin Acid, Sodium Salt. Grades: > 95%. Molecular formula: C25H39O7 Na. Mole weight: 451.59 22.99.
(3R)-Hydroxperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3R,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 1092716-42-1. Molecular formula: C25H38O7. Mole weight: 450.57.
(3S, 5S)-Dihydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?6,?7,?8,?8a-octahydro-4,?6-dihydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α, ?3α, ?4β, ?6α, ?7β, ?8β(2S*, ?4S*)?, ?8aβ]?]?- (9CI). Grades: > 95%. CAS No. 159143-77-8. Molecular formula: C25H40O7. Mole weight: 452.58.
(3S)-Hydroxperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3S,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grades: > 95%. CAS No. 1092716-44-3. Molecular formula: C25H38O7. Mole weight: 450.57.
(4S)-Hydroxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?7,?8-hexahydro-4-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α, ?3α, ?4β, ?7β, ?8β(2S*, ?4S*)?]?]?- (9CI). Grades: > 95%. CAS No. 149949-05-3. Molecular formula: C25H38O6. Mole weight: 434.57.
6S)-Hydroperoxy Simvastatin
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?6S,?7R,?8S,?8aR)?-1,?2,?6,?7,?8,?8a-hexahydro-6-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester; Butanoic acid, 2,2-dimethyl-, 1,2,6,7,8,8a-hexahydro-6-hydroperoxy-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α, 6α, 7β, 8β(2S*, 4S*), 8aβ]]- (9CI). Grades: > 95%. CAS No. 149949-01-9. Molecular formula: C25H38O7. Mole weight: 450.57.
Dehydro Simvastatin
Simvastatin impurity. Group: Biochemicals. Alternative Names: 2,2-Dimethylbutanoic Acid (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-Dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl Ester. Grades: Highly Purified. CAS No. 210980-68-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Lovastatin (Mevinolin)
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent). Uses: Antioxidant / antihypercholesterolemic / antiarrhythmic. Synonyms: Mevacor; Monacolin K; Altoprev; MK 803; MK-803; MK803; Monacolin K; QAB149; MSD 803; Simvastatin EP Impurity E; Simvastatin USP Related Compound E; Desmethyl Simvastatin. Grades: >98%. CAS No. 75330-75-5. Molecular formula: C24H36O5. Mole weight: 404.54.
Simvastatin 4'-Methyl Ether
Simvastatin 4'-Methyl Ether. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-methoxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl 2,2-dimethylbutanoate,Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-methoxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-Methoxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate. CAS No. 864357-88-0. IUPAC Name: [(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-methoxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate. Molecular formula: C26H40O5. Mole weight: 432.59. Catalog: APS864357880. SMILES: CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@H](CC(=O)O3)OC)[C@@H]12. Format: Neat.
Simvastatin Hydroxy Acid Ethyl Ester
An impurity in Simvastatin. Group: Biochemicals. Alternative Names: ( βR, δR, 1S, 2S, 6R, 8S, 8aR)-8-(2, 2-Dimethyl-1-oxobutoxy)-1, 2, 6, 7, 8, 8a-hexahydro- β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 864357-87-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Simvastatin Hydroxy Acid Methyl Ester
An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: (βR,δR,1S,2S,6R,8S,8aR)-8-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro -β,δ-dihydroxy-2,6-dimethyl-1-naphthaleneheptanoic Acid Methyl Ester. Grades: > 95%. CAS No. 145576-26-7. Molecular formula: C26H42O6. Mole weight: 450.62.