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Sitagliptin. Group: Biochemicals. Alternative Names: (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4- triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one. Grades: Highly Purified. CAS No. 486460-32-6. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C16H15F6N5O, Molecular Weight: 407.31. US Biological Life Sciences.
Worldwide
Sitagliptin
Sitagliptin (MK-0431) is a potent and orally active inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431. CAS No. 486460-32-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749.
Sitagliptin
Sitagliptin (MK 0431) is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. Sitagliptin is used as a hypoglycemic agent to treat type 2 diabetes. Uses: The treatment of type 2 diabetes. Synonyms: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; MK0431; Xelevia; Januvia; Tesavel; NSC813215; (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone; 1,2,4-triazolo[4,3-a]pyrazine-7(8H)-propanamine, 5,6-dihydro-γ-oxo-3-(trifluoromethyl)-α-[(2,4,5-trifluorophenyl)methyl]-, (αR)-. Grade: >98%. CAS No. 486460-32-6. Molecular formula: C16H15N5OF6. Mole weight: 407.31.
Sitagliptin Carbamoyl β-D-Glucuronide
A metabolite of Sitagliptin. Group: Biochemicals. Alternative Names: 1- [N- [ (1R) -3- [5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo [4, 3-a] pyrazin-7 (8H) -yl] -3-oxo-1- [ (2, 4, 5-trifluorophenyl) methyl] propyl] carbamate] . Grades: Highly Purified. CAS No. 940002-59-5. Pack Sizes: 1mg. US Biological Life Sciences.
An isotope labelled Sitagliptin. Sitagliptin, marketed as the phosphate salt, is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (3R)-3-amino-1-[3-(trifluoromethyl)(5,5,6,6-D4)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; (R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine D4. Grade: >98%. CAS No. 1426173-93-4. Molecular formula: C16H11D4F6N5O. Mole weight: 411.34.
Sitagliptin-d4 phosphate
Sitagliptin-d 4 (phosphate) is the deuterium labeled Sitagliptin phosphate. Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC50 of 19 nM in Caco-2 cell extracts[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1432063-88-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-13749AS.
Sitagliptin-d4 Phosphate
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-d4 Phosphate; Januvia-d4;MK 0431-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Sitagliptin FP Impurity E Hydrochloride
Sitagliptin EP Impurity E is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 17 HCl; Sitagliptin Acid Impurity HCl; (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride; (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride. Grade: >95%. CAS No. 1204818-19-8. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65.
Sitagliptin Impurity 04
Sitagliptin Impurity 04. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1675201-14-5. Molecular formula: C16H12F6N4O. Mole weight: 390.29. Catalog: APB1675201145.
Sitagliptin Impurity 05
Sitagliptin Impurity 05. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1253056-18-6. Molecular formula: C16H12F6N4O. Mole weight: 390.29. Catalog: APB1253056186.
Sitagliptin Impurity 09
Sitagliptin Impurity 09. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1253056-01-7. Molecular formula: C16H14F6N4O2. Mole weight: 408.3. Catalog: APB1253056017.
Sitagliptin Impurity 19
Sitagliptin Impurity 19 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-Sitagliptin N-Boc-Acid Impurity; (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid; Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid. Grade: >95%. CAS No. 486460-00-8. Molecular formula: C15H18F3NO4. Mole weight: 333.3.
Sitagliptin Impurity 21
Sitagliptin Impurity 21 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Boc-D-β-homophenylalanine; Boc-D-β-Homophe-OH; (R)-3-(Boc-amino)-4-phenylbutyric acid; N-β-(t-Butoxycarbonyl)-D-β-homophenylalanine. Grade: >97%. CAS No. 101555-61-7. Molecular formula: C15H21NO4. Mole weight: 279.33.
Sitagliptin Impurity 22
Sitagliptin Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1253055-94-5. Molecular formula: C19H20F3NO5. Mole weight: 399.37. Catalog: APB1253055945.
Sitagliptin Impurity 29
Sitagliptin Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1334244-28-8. Molecular formula: C16H16F5N5O. Mole weight: 389.33. Catalog: APB1334244288.
Sitagliptin Impurity 46
Sitagliptin Impurity 46. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1234321-81-3. Molecular formula: C13H12F3NO3. Mole weight: 287.24. Catalog: APB1234321813.
Sitagliptin Impurity 61
Sitagliptin Impurity 61. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1253055-92-3. Molecular formula: C11H12F3NO2. Mole weight: 247.22. Catalog: APB1253055923.
Sitagliptin Impurity 62
Sitagliptin Impurity 62. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1234321-83-5. Molecular formula: C13H14F3NO3. Mole weight: 289.25. Catalog: APB1234321835.
Sitagliptin Impurity 67
Sitagliptin Impurity 67. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1032506-99-2. Molecular formula: C11H10F2O3. Mole weight: 228.19. Catalog: APB1032506992.
Sitagliptin Impurity 74
Sitagliptin Impurity 74. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256815-03-8. Molecular formula: C10H7F3O3. Mole weight: 232.16. Catalog: APB1256815038.
Sitagliptin phosphate is the phosphate salt form of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Uses: Hypoglycemic agents. Synonyms: (2R)-4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-amine phosphate salt; MK-431; ONO-5435. Grade: >98%. CAS No. 654671-78-0. Molecular formula: C16H15F6N5O.H3O4P. Mole weight: 505.31.
Sitagliptin phosphate
Sitagliptin phosphate (MK-0431 phosphate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate. CAS No. 654671-78-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749A.
Sitagliptin phosphate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Sitagliptin Phosphate
Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-phosphate. Grades: Highly Purified. CAS No. 654671-78-0. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Sitagliptin phosphate monohydrate
Sitagliptin phosphate monohydrate (MK-0431 phosphate monohydrate) is a potent inhibitor of DPP4 with an IC 50 of 19 nM in Caco-2 cell extracts [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0431 phosphate monohydrate. CAS No. 654671-77-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13749B.
An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release, stimulates the insulin release and lowers blood glucose. Group: Biochemicals. Grades: Highly Purified. CAS No. 654671-77-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Sitagliptin Related Compound 1
Sitagliptin Related Compound 1 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-Butoxycarbonyl)amino)-4-(3-fluorophenyl)butanoic acid; Boc-(R)-3-amino-4-(3-fluorophenyl)-butyric acid. Grade: >95%. CAS No. 331763-66-7. Molecular formula: C15H20FNO4. Mole weight: 297.32.
Sitagliptin System Suitability Mixture
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
3-Amino-4- (2, 4, 5-trifluorophenyl) butanyl Sitagliptin is an impurity of Sitagliptin (S490990). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 2072867-07-1. Pack Sizes: 50mg, 100mg. Molecular Formula: C26H23F9N6O2, Molecular Weight: 622.49. US Biological Life Sciences.
Worldwide
3-Desamino-2,3-dehydro sitagliptin
3-Desamino-2,3-dehydro sitagliptin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1253056-18-6. Molecular formula: C16H12F6N4O. Mole weight: 390.28. Catalog: APS1253056186. Format: Neat.
3-Desamino-3,4-dehydro Sitagliptin
3-Desamino-3,4-dehydro Sitagliptin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1803026-58-5. Pack Sizes: 5MG. IUPAC Name: (E)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-3-en-1-one. Molecular formula: C16H12F6N4O. Mole weight: 390.28. Catalog: APS1803026585. SMILES: Fc1cc(F)c(\C=C\CC(=O)N2CCn3c(C2)nnc3C(F)(F)F)cc1F. Format: Neat. Shipping: Room Temperature.
3-Desamino Acetoxy Sitagliptin
3-Desamino Acetoxy Sitagliptin is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 4-Oxo-4-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl)butan-2-yl Acetate. CAS No. 1675201-16-7. Molecular formula: C18H16F6N4O3. Mole weight: 450.33.
(3-Des-trifluoromethyl-3-methyl) Sitagliptin
(3-Des-trifluoromethyl-3-methyl) Sitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C16H18F3N5O. Mole weight: 353.34.
4-Desfluoro-destrifluoromethyl Sitagliptin Hydrochloride Salt
4-Desfluoro-destrifluoromethyl Sitagliptin Hydrochloride Salt is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-Amino-4-(2,5-difluorophenyl)-1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one Hydrochloride Salt. Molecular formula: C15H18ClF2N5O. Mole weight: 357.79.
5-Desfluoro-destrifluoromethyl Sitagliptin Hydrochloride Salt
5-Desfluoro-destrifluoromethyl Sitagliptin Hydrochloride Salt is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-Amino-4-(2,4-difluorophenyl)-1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one Hydrochloride Salt. Molecular formula: C15H18ClF2N5O. Mole weight: 357.79.
Bis-benzyl Sitagliptin Maleate Adduct
Bis-benzyl Sitagliptin Maleate Adduct is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Bis-benzyl Sitagliptin Fumarate Adduct. Molecular formula: C34H29F6N5O5. Mole weight: 701.61.
Desfluoro Sitagliptin
Desfluoro Saitagliptin is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-Amino-4-phenyl-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one. Molecular formula: C16H18F3N5O. Mole weight: 353.34.
N-Acetyl Sitagliptin
N-Acetyl Sitagliptin is the N-acetylated derivative of the trizolopyrazine dipeptidyl peptidase IV inhibitor, Sitagliptin. Group: Biochemicals. Alternative Names: 7-[(3R)-3-[(N-Acetyl)Amino]-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine. Grades: Highly Purified. CAS No. 1379666-94-0. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
rac-Sitagliptin
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine. Grades: Highly Purified. CAS No. 823817-56-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Rac-Sitagliptin-[d4] hydrochloride
Rac-Sitagliptin-[d4] hydrochloride is the labelled salt of Rac-Sitagliptin, which is a trizolopyrazine dipeptidyl peptidase IV (DPP-4) inhibitor. Sitagliptin is a medication used to treat diabetes mellitus type 2. Synonyms: (Rac)-Sitagliptin-d4 hydrochloride; 7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-d4 Hydrochloride. Grade: 99% by HPLC. CAS No. 1620233-77-3. Molecular formula: C16H12D4ClF6N5O. Mole weight: 411.34.
Rac-Sitagliptin-Desfluoro Impurity
Rac-Sitagliptin-Desfluoro Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1334244-32-4. Molecular formula: C16H16F5N5O. Mole weight: 389.33. Catalog: APB1334244324.
(R)-Sitagliptin Defluoro Impurity 3
Sitagliptin Defluoro Impurity 3 is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoic acid; (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4-difluorophenyl)butanoic acid. Grade: >90%. CAS No. 851307-12-5. Molecular formula: C15H19F2NO4. Mole weight: 315.31.
(R)-Sitagliptin Defluoro Impurity 4
(R)-Sitagliptin Defluoro Impurity 4 is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin impurity R; (R)-beta-(Boc-amino)-2,5-difluorobenzenebutanoic acid; (R)-3-[((tert-Butoxy)carbonyl)amino]-4-(2,5-difluorophenyl)butanoic acid. CAS No. 486459-98-7. Molecular formula: C15H19F2NO4. Mole weight: 315.31.
(R)-Sitagliptin N-Boc-Methyl-Ester Impurity
(R)-Sitagliptin N-Boc-Methyl-Ester Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 45; (R)-Methyl 3-(t-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoate; methyl (R)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoate. Grade: >95%. CAS No. 881995-73-9. Molecular formula: C16H20F3NO4. Mole weight: 347.33.
(±)-Sitagliptin-d4 hydrochloride
(±)-Sitagliptin-d4 is intended for use as an internal standard for the quantification of sitagliptin by GC- or LC-MS. Sitagliptin i and (+)-sitagliptin, also known as sitagliptin impurity E, a potential impurity found in commercial preparations of (-)-sitagliptin. Synonyms: 3-amino-1-[5,6-dihydro-5,6-d2-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl-5,6-d2]-4-(2,4,5-trifluorophenyl)-1-butanone monohydrochloride. Grade: ≥99% atom D. Molecular formula: C16H11D4F6N5O·HCl. Mole weight: 447.80.
(S)-Sitagliptin N-Boc-Acid Impurity
(S)-Sitagliptin N-Boc-Acid Impurity is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 41; Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid; (βS)?-β-[[(1,?1-Dimethylethoxy)?carbonyl]?amino]?-2,?4,?5-trifluoro-benzenebutanoic Acid; (S)-3-((tert-butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic acid. Grade: >95%. CAS No. 922178-94-7. Molecular formula: C15H18F3NO4. Mole weight: 333.3.
1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1253056-01-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C16H14F6N4O2. US Biological Life Sciences.
Worldwide
1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine
1-(Chloroacetyl)-2-(trifluoroacetyl)hydrazine is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 2,2,2-Trifluoroacetic Acid 2-(2-Chloroacetyl)hydrazide; N'-(chloroacetyl)-2,2,2-trifluoroacetohydrazide. Grade: >95%. CAS No. 762240-99-3. Molecular formula: C4H4ClF3N2O2. Mole weight: 204.53.
2,2,2-Trifluoro-N'-(trifluoroacetyl)acetohydrazide is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: 2,2,2-trifluoro-N'-(2,2,2-trifluoroethanoyl)ethanehydrazide. Grade: 95%. CAS No. 667-35-6. Molecular formula: C4H2F6N2O2. Mole weight: 224.06.
2,?4,?5-?Trifluoro-benzeneacetic acid methyl ester is used for the synthesis of Dipeptidyl Peptidase-?4 (DPP-?4) Inhibitor, (R)?-?Sitagliptin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036273-20-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C9H7F3O2, Molecular Weight: 204.15. US Biological Life Sciences.
2,4,5-Trifluoro-L-β-homophenylalanine hydrochloride is used as a reagent in the synthesis of valuable β-amylalkyl-β-amino acid enantiomers. It is also an impurity of Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: (S)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid hydrochloride. Grade: 95%. CAS No. 1217809-78-3. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65.
2,4,5-Trifluorophenylacetic acid
2,4,5-Trifluorophenylacetic acid is used in the synthesis of EGFR/ErbB-2-kinase inhibitors. It is also used in the synthesis of new imidazopyrazinone derivatives as potnetial dipeptidyl peptidase IV inhibitors. 2,4,5-Trifluorophenylacetic acid is an impurity of Sitagliptin. Synonyms: Benzeneacetic acid, 2,4,5-trifluoro-; (2,4,5-Trifluorophenyl)acetic acid. Grade: 99%. CAS No. 209995-38-0. Molecular formula: C8H5F3O2. Mole weight: 190.12.
2,4-Difluorophenylacetic acid
2,4-Difluorophenylacetic acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: 2-(2,4-difluorophenyl)acetic acid. Grade: 99%. CAS No. 81228-09-3. Molecular formula: C8H6F2O2. Mole weight: 172.13.
2-Carboxy-3,4,6-trifluorobenzeneacetic acid
An impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 120. Grade: ≥95%. CAS No. 2428591-91-5. Molecular formula: C9H5F3O4. Mole weight: 234.13.
2-(chloromethyl)-5-(trifluoromethyl)-1,3,4-oxadiazole is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: 2-Chloromethyl-5-trifluoromethyl-1,3,4-oxadiazole. Grade: 98.0 %. CAS No. 723286-98-4. Molecular formula: C4H2ClF3N2O. Mole weight: 186.52.
2-Hydrazinopyrazine
2-Hydrazinopyrazine is used as a reagent in the synthesis of Sitagliptin (S491000, H3PO4) and its analogs. Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor that has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 54608-52-5. Pack Sizes: 250mg, 1g. Molecular Formula: C4H6N4, Molecular Weight: 110.12. US Biological Life Sciences.
2-[[(R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-yl]amino]succinic Acid is a derivative of the parent compound Sitagliptin Phosphate (S491000), which is a trizolopyrazine dipeptidyl peptidase IV inhibitor and it has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C24H17F6N5O3, Molecular Weight: 537.41. US Biological Life Sciences.
(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an impurity of Sitagliptin. Sitagliptin is an dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: SCHEMBL23269993; 1803026-54-1; (Z)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one. CAS No. 1803026-54-1. Molecular formula: C16H12F6N4O. Mole weight: 390.28.
(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803026-54-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H12F6N4O. US Biological Life Sciences.
Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension. Group: Biochemicals. Alternative Names: (2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one; 2,3-Desdihydrogen rac-Sitagliptin. Grades: Highly Purified. CAS No. 767340-03-4. Pack Sizes: 5mg. US Biological Life Sciences.
Isotope labelled Sitagliptin (S491000) intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 1620233-76-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H9D4F6N5O. US Biological Life Sciences.
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3,4-Difluorophenylacetic acid
3,4-Difluorophenylacetic acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Synonyms: 2-(3,4-difluorophenyl)acetic acid. Grade: 99%. CAS No. 658-93-5. Molecular formula: C8H6F2O2. Mole weight: 172.13.
An impurity of Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of diabetes mellitus type 2. Grade: 95%. CAS No. 1909337-07-0. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65.
3- ( ( (Benzyloxy) carbonyl) amino) -4- (2, 4, 5-trifluorophenyl) butanoic Acid is an intermediate in the synthesis of Sitagliptin Triazecine Analog (S491015). Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C18H16F3NO4. US Biological Life Sciences.
3-(((Benzyloxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Molecular formula: C18H16F3NO4. Mole weight: 367.32.
3-Trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Intermediate 1 of sitagliptin phosphate. CAS No. 762240-92-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-76120.
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