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| Product | Description | |
|---|---|---|
| C2 Ceramide | C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis , inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ceramide 2. CAS No. 3102-57-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101180. |  |
| Cholesterol | Cholesterol is a natural waxy substance that is found in human skin and is also commonly used in cosmetics and skincare products. In cosmetics, cholesterol is used as a moisturizer and emollient to help soften and smooth the skin, as well as to improve the appearance of fine lines and wrinkles. It is also believed to help strengthen the skin's barrier function and protect against environmental damage. The chemical formula of cholesterol is C27H46O, and it typically appears as a white or off-white powder or solid. It is also available in liquid form, often in combination with other ingredients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3β-Hydroxycholest-5-ene. Product Category: Cholesteryl Esters. Appearance: White powder. CAS No. 57-88-5. Molecular formula: C27H46O. Mole weight: 386.66. Purity: 0.98. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Density: 1.06 g/cm³. Product ID: ACM57885. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Dexchlorpheniramine maleate | Dexchlorpheniramine maleate is an orally taken anti- histamine that has anti-inflammatory, anti-irritant, anti-allergic, and skin barrier effects. Dexchlorpheniramine maleate inhibits myocardial contraction in rats. Dexchlorpheniramine maleate can be used in studies of allergic rhinitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-(+)-Chlorpheniramine maleate salt. CAS No. 2438-32-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-B1062. | |
| Epinastine | Epinastine is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is highly selective for the H1 receptor and does not cross the blood-brain-barrier. It shows a high affinity to H1-receptors in receptor binding studies in the guinea pig ileum. It inhibits histamine-induced reactions in the skin or the lung of rats, dogs and guinea pigs. It is able to displace specific [3H]NC-5Z binding at low concentrations in the locust nervous tissue. It antagonises octopamine-induced cAMP formation in the insect brain. It is effective in inhibiting not only Ca2+ uptake into lung mast cells in actively sensitized guinea pigs but also Ca2+ release from the intracellular Ca store of rat peritoneal mast cells exposed to both compound 48/80 and substance. It is produced by Allergan and marketed by Inspire in the United States. Uses: Epinastine is used in eye drops to treat allergic conjunctivitis. it is highly selective for the h1 receptor and does not cross the blood-brain-barrier. Synonyms: 9,13b-Dihydro-1H-dibenz[c,f]imidazo[1,5-a]azepin-3- amine;3-Amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine;Apinastine Base;WAL 801. Grades: >98%. CAS No. 80012-43-7. Molecular formula: C16H15N3. Mole weight: 249.31. |  |
| Levan | Levan is a fructose derivative, it is moisturizing and anti-inflammatory, it is also used to help improve skin barrier function. Uses: Designed for use in research and industrial production. Product Category: Heterocyclic Organic Compound. CAS No. 9013-95-0. Molecular formula: C18H32O16. Density: 1.82 g/cm³. Product ID: ACM9013950. Alfa Chemistry ISO 9001:2015 Certified. | |
| Levan - from Jerusalem artichoke | Levan is a fructose derivative, it is moisturizing and anti-inflammatory, it is also used to help improve skin barrier function. CAS No. 9013-95-0. Molecular formula: (C6H10O5)n. | |
| Myristyl nicotinate | Myristyl nicotinate (Tetradecyl nicotinate) is an ester proagent and a lipophilic derivative of Nicotinic acid. Myristyl nicotinate is being developed for delivery of Nicotinic acid into the skin for prevention of actinic keratosis and its progression to skin cancer. Myristyl nicotinate shows to stimulate epidermal differentiation in photodamaged skin, increasing skin NAD content and strengthening the skin barrier [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tetradecyl nicotinate. CAS No. 273203-62-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-133027. | |
| N-Acetyl-L-Hydroxy proline | N-acetyl-l-hydroxyproline (AHYP) is an acetylated form of l-hydroxyproline. CAS No. 33996-33-7. Product ID: PAP-0017. Molecular formula: C7H11NO4. Category: Amino acid. Product Keywords: Amino Acid Series; N-Acetyl-L-Hydroxy proline; PAP-0017; Amino acid; C7H11NO4; 33996-33-7. Color: White. EC Number: 251-780-6. Physical State: Crystalline Powder. Solubility: DMSO : ≥ 32 mg/mL (184.79 mM). Storage: Sealed in dry,2-8°C. Applications: N-Acetyl-L-Hydroxy proline is used to treat skin ulcers and porphyria cutanea tarda. Its other biological and physiological effects on the skin have not been elucidated. We investigated the effects of AHYP on the skin-barrier function, focusing on ceramide synthesis and the effects of topical AHYP on atopic dermatitis. Boiling Point: 303.8°C (rough estimate). Melting Point: 132-133 °C (dec.)(lit.). Density: 1.3346 (rough estimate). Product Description: N-Acetyl-L-Hydroxy proline is used to treat skin ulcers and porphyria cutanea tarda. Its other biological and physiological effects on the skin have not been elucidated. We investigated the effects of AHYP on the skin-barrier function, focusing on ceramide synthesis and the effects of topical AHYP on atopic dermatitis. |  |
| Niacinamide | Niacinamide (Nicotinamide) is vitamin B3, an essential nutrient. It provides both nutritional and topical benefits. As a skin care active, niacinamide can improve the appearance of hyperpigmented skin, reduce redness, fine lines and wrinkles, smooth skin texture and enhance skin barrier properties. Uses: Niacinamide is suitable for serums, masks, facial cleansers, lotions, astringents, creams, moisturizers, conditioners, toners, and foundations. Recommended for skin lightening, anti-wrinkle, pore size reduction, anti-inflammatory, anti-acne, and skin barrier improvement. Group: Skin Lightening, Anti-inflammation, Anti-wrinkle, Anti-aging. Alternative Names: Nicotinamide, Vitamin B3. CAS No. 98-92-0. Pack Sizes: 20kg, 3x20kg, 1kg. Categories: 3-pyridinecarboxamide; nicotinic acid amide. |  United States and all of its trading partners.. |
| Oxybenzone | Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy , alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Benzophenone 3. CAS No. 131-57-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-A0067. | |
| PF 5274857 hydrochloride | PF 5274857 hydrochloride is a high affinity and selective Smoothened (Smo) receptor antagonist (Ki = 4.6 nM), with >1000-fold selectivity for Smo over a panel of other receptors, ion channels and enzymes. When administered orally, it distributes through plasma to skin and tumor and remains metabolically stable. PF 5274857 also penetrates the blood-brain barrier and inhibits Smo activity in the brain. Synonyms: PF 5274857 hydrochloride; PF5274857 hydrochloride; PF-5274857 hydrochloride; 1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride. Grades: ≥98% by HPLC. CAS No. 1613439-62-5. Molecular formula: C20H25ClN4O3S.HCl. Mole weight: 473.42. | |
| Poly(1-vinylpyrrolidone)-graft-(1-triacontene) | Film former with surface activity, water resistance and barrier properties. Uses: Pigment dispersant and wetting agent, substantive to skin. Group: Hydrophilic polymershydrophobic polymerspolymers. Alternative Names: POLY(1-VINYLPYRROLIDONE)-GRAFT-(1-TRIACONTENE); TRICONTANYL PVP; Alkenes, C>10.alpha.-, polymers with vinylpyrrolidone; POLYVINYLPYRROLIDONE1-TRIACONTENECOPOLYMER; 1-ETHENYL-2-PYRROLIDONE,POLYMERWITH1-TRIACONTENE; vinylpyrrolidone/ 1-triacontene copolymer; Pol. CAS No. 136445-69-7. Pack Sizes: 100 g in poly bottle. Product ID: diethyl6a-amino-1,6-bis(carbamoylamino)-3a-cyano-2,5-dimethylpyrrolo[2,3-b]pyrrole-3,4-dicarboxylate. Molecular formula: 436.42246;g/mol. Mole weight: C17H24N8O6. CCOC (=O)C1=C (N (C2 (C1 (C (=C (N2NC (=O)N)C)C (=O)OCC)C#N)N)NC (=O)N)C. UFKDCMAMQUXQLZ-UHFFFAOYSA-N. 96%. |  |
| Telavancin hydrochloride | Telavancin hydrochloride is the hydrochloride form of Telavancin (HY-112959). Telavancin hydrochloride is a semisynthetic derivative of vancomycin, and exhibits antibacterial efficacy through inhibition of cell wall synthesis and disruption of cell membrane barrier function. Telavancin hydrochloride is efficient against antibiotic resistant S. aureus strains MRSA, VISA, and hVISA. Telavancin hydrochloride attenuates gram positive bacteria induced complicated skin and skin structure infections (cSSSI) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-6424 hydrochloride. CAS No. 560130-42-9. Pack Sizes: 1 mg. Product ID: HY-16485. | |
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