Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Sofosbuvir | Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC 50 of 92 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-7977; PSI-7977. CAS No. 1190307-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15005. |  |
| Sofosbuvir | Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SOFOSBUVIR;PSI-7977;SOVALDI;1190307-88-0;GS-7977;PSI 7977;UNII-WJ6CA3ZU8B;GS7977;WJ6CA3ZU8B;CHEBI:85083;Sofosbuvir [USAN:INN];C22H29FN3O9P;Hepcinat;Hepcvir;Resof;SoviHep;HSDB 8226;PSI7977;Sovaldi (TN);Sofosbuvir (PSI-7977, GS-7977);Sofosbuvir (JAN/USAN);Sofosbuvir(PSI-7977);2-((5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy)phenoxyphosphorylamino. Product Category: Inhibitors. Appearance: Solid. CAS No. 1190307-88-0. Molecular formula: C22H29FN3O9P. Mole weight: 529.5g/mol. Purity: 0.9993. IUPACName: propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate. Canonical SMILES: CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3. Product ID: ACM1190307880. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Sofosbuvir-[13C,d3] | Sofosbuvir-[13C,d3] is the labelled analogue of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Sofosbuvir 13CD3. Grade: 95% by HPLC; 95% atom 13C; 95% atom D. CAS No. 2070009-25-3. Molecular formula: C21[13C]H26D3FN3O9P. Mole weight: 533.46. |  |
| Sofosbuvir-[d6] | Sofosbuvir-[d6] is the labelled analogue of Sofosbuvir. Sofosbuviis a medication used for the treatment of hepatitis C. Synonyms: Sofosbuvir D6; N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-(Methyl-d3)ethyl-2,2,2-d3 Ester. Grade: 95% by HPLC; 98% atom D. CAS No. 1868135-06-1. Molecular formula: C22H23D6FN3O9P. Mole weight: 535.49. | |
| Sofosbuvir Impurity 15 | Sofosbuvir Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1334513-02-8. Molecular formula: C18H17F5NO5P. Mole weight: 453.3. Catalog: APB1334513028. |  |
| Sofosbuvir Impurity 25 | Sofosbuvir Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1015073-43-4. Molecular formula: C10H14FN2O8P. Mole weight: 340.2. Catalog: APB1015073434. | |
| Sofosbuvir Impurity 26 | Sofosbuvir Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1859162-80-3. Molecular formula: C16H18FN2O8P. Mole weight: 416.3. Catalog: APB1859162803. | |
| Sofosbuvir Impurity 35 | Sofosbuvir Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1233335-82-4. Molecular formula: C16H25FN3O9P. Mole weight: 453.36. Catalog: APB1233335824. | |
| Sofosbuvir Impurity 8 | Sofosbuvir Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1337482-15-1. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. Catalog: APB1337482151. | |
| Sofosbuvir Impurity 9 | Sofosbuvir Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1337482-17-3. Molecular formula: C34H45FN4O13P2. Mole weight: 798.69. Catalog: APB1337482173. | |
| Sofosbuvir metabolite GS331007-[13C,d3] | An isotope labelled metabolite of Sofosbuvir. Sofosbuviis a medication used for the treatment of hepatitis C. Grade: 95% by HPLC; 98% atom D;98% atom 13C. CAS No. 1256490-42-2. Molecular formula: C9[13C]H10D3FN2O5. Mole weight: 264.23. | |
| Sofosbuvir metabolite GS-566500-[13C,d3] | An isotope labelled impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2S)-2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)amino)propanoic-13CD3 Acid; O-Desisopropyl O-Desphenyl Sofosbuvir-13C,D3; PSI 352707-13C,D3. Grade: > 95%. CAS No. 1256490-46-6. Molecular formula: [13C]C12H16FN3O9PD3. Mole weight: 415.29. | |
| Sofosbuvir (PSI-7977, GS-7977) | PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Alternative Names: Isopropyl (2S) -2- [ [ [ (2R, 3R, 4R, 5R) -5- (2, 4-dioxopyrimidin-1-yl) -4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl] methoxy-phenoxy-phosphoryl] amino] propanoate; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-1-methylethyl Ester L-Alanine; GS-7977; PSI-7977. Grades: Highly Purified. CAS No. 1190307-88-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C22H29FN3O9P, Molecular Weight: 529.45. US Biological Life Sciences. |  Worldwide |
| Sofosbuvir (R)-Phosphate | Sofosbuvir (R)-Phosphate. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS003089. Format: Neat. | |
| 2-Defluro-2-hydroxy 2-epi-Sofosbuvir | 2-Defluro-2-hydroxy 2-epi-Sofosbuvir is an impurity of Sofosbuvir (P839640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H30N3O10P, Molecular Weight: 527.46. US Biological Life Sciences. | Worldwide |
| 2-Defluro-2-hydroxy 2-epi-Sofosbuvir-13Cd3 | 2-Defluro-2-hydroxy 2-epi-Sofosbuvir-13Cd3 is the labelled form of 2-Defluro-2-hydroxy 2-epi-Sofosbuvir (D228775), which is an impurity of Sofosbuvir (P839640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C2113CH27D3N3O10P, Molecular Weight: 531.47. US Biological Life Sciences. | Worldwide |
| 2-Defluro-2-methylene Sofosbuvir | 2-Defluro-2-methylene Sofosbuvir is an impurity of Sofosbuvir (P839640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H28N3O9P, Molecular Weight: 509.45. US Biological Life Sciences. | Worldwide |
| 2'-epi-Sofosbuvir Desphosphate | 2'-epi-Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| 2-epi-Sofosbuvir Desphosphate | 2-epi-Sofosbuvir Desphosphate is possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H13FN2O5, Molecular Weight: 260.22. US Biological Life Sciences. | Worldwide |
| 3'-O-Benzyl Sofosbuvir Desphosphate | 3'-O-Benzyl Sofosbuvir Desphosphate may be a metabolite of Sofosbuvir, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: 1-((2R,3R,4R,5R)-4-(Benzyloxy)-3-fluoro-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Molecular formula: C17H19FN2O5. Mole weight: 350.34. | |
| 5'O-Benzyl Sofosbuvir Desphosphate | 5'O-Benzyl Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Synonyms: 5'-O-Benzyl RO 2433. Molecular formula: C17H19FN2O5. Mole weight: 350.34. | |
| Chloro Sofosbuvir | Chloro Sofosbuvir is an impurity of Sofosbuvir; a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: N-[[P(S),2'R]-2'-Chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. Grade: ≥98% (HPLC). CAS No. 1496552-51-2. Molecular formula: C22H29ClN3O9P. Mole weight: 545.91. | |
| ent-Sofosbuvir Desphosphate | ent-Sofosbuvir Desphosphate is a possible metabolite of prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| 1-((2R,3R,4R,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | 1-((2R,3R,4R,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a powerful antimicrobial agent, is renowned for its efficacy in treating a range of bacterial and fungal infections, including those caused by Candida, Aspergillus, and Cryptococcus species. This pharmaceutical marvel works by clobbering the synthesis of crucial nucleic acids in microbes to sabotage their survival. Notably, its phenomenal antibacterial and antifungal activity renders it an essential tool in the battle against streptococcal and staphylococcal infections. Synonyms: Sofosbuvir impurity SA15432. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| 1-β-D-Arabinofuranosyluracil-2-C-methyl-d3,13C | 1-β-D-Arabinofuranosyluracil-2-C-methyl-d3, 13C is the labeled analogue of 1-β-D-Arabinofuranosyluracil-2-C-methyl, an impurity of PSI-7977, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: 1-(2-C-Methyl-d3, 13C-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyl-d3, 13C-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; Sofosbuvir Impurity 12-d3, 13C. CAS No. 1256490-38-6. Molecular formula: C9[13C]H11D3N2O6. Mole weight: 262.24. | |
| 2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt | PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively. Synonyms: 2'-F-2'-C-Me-dUTP.4Na; (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine 5'-(tetrahydrogen triphosphate) sodium salt; GS 461203 sodium salt; PSI 7409 sodium salt; Sofosbuvir triphosphate sodium salt; Sofosbuvir-TP sodium salt; PSI-7409 tetrasodium; Uridine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2'-fluoro-2'-methyl-, sodium salt (1:4), (2'R)-. Grade: ≥95% by HPLC. CAS No. 1621884-22-7. Molecular formula: C10H12FN2Na4O14P3. Mole weight: 588.09. | |
| (2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine | PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Synonyms: RO-2433; RO 2433; RO2433; PSI6206; PSI 6206; PSI-6206; GS331007; GS-331007; GS 331007; 2'-Deoxy-2'-fluoro-2'-C-methyluridine; Sofosbuvir Metabolite GS331007; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine; ZL-01 metabolite M9; 2'-Deoxy-2'-Fluoro-2'-methyluridine. Grade: ≥95%. CAS No. 863329-66-2. Molecular formula: C10H13FN2O5. Mole weight: 260.22. | |
| (2'R)?-2'-?Deoxy-?2'-?fluoro-?2'-?methyl-uridine 5'-?Triphosphate Triethylammonium Salt | (2'R)?-2'-?Deoxy-?2'-?fluoro-?2'-?methyl-uridine 5'-?Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C28H61FN5O14P3. US Biological Life Sciences. | Worldwide |
| (2'R)?-2'-?Deoxy-?2'-?fluoro-?2'-?methyl-uridine 5'-?Triphosphate Triethylammonium Salt | (2'R)?-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir. That prodrug could be metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate. Synonyms: Sofosbuvir Impurity; RO 2433 Triphosphate Triethylammonium Salt. Grade: 95%. Molecular formula: C28H61FN5O14P3. Mole weight: 803.73. | |
| (2'R) -2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-uridine | (2'R) -2'-Deoxy-3', 5'-bis-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-uridine is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1393526-40-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C22H41FN2O5Si2. US Biological Life Sciences. | Worldwide |
| (2'R) -2'-Deoxy-3'-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-uridine | (2'R) -2'-Deoxy-3'-O-[ (1, 1-dimethylethyl) dimethylsilyl]-2'-fluoro-2'-methyl-uridine is an intermediate in the synthesis of Sofosbuvir (R)-Phosphate (S675615), which is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1244762-86-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C16H27FN2O5Si. US Biological Life Sciences. | Worldwide |
| [(2R,3R,4R)-3-(Benzoyloxy)-4-fluoro-4-methyl-5-oxotetrahydrofuran-2-yl]methyl Benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: benzoic acid [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-2-oxolanyl]methyl ester; D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, γ-lactone, 3,5-dibenzoate, (2R)-; (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythro-pentonic acid γ-lactone 3,5-dibenzoate. Grade: ≥95%. CAS No. 874638-80-9. Molecular formula: C20H17FO6. Mole weight: 372.34. | |
| ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methyltetrahydrofuran-2-yl)methyl benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidine-1(2H)-yl )-4-methyltetrahydrofuran-2-pyridin-3-yl)methyl benzoate. Grade: 98%. CAS No. 1496551-71-3. Molecular formula: C24H21ClN2O7. Mole weight: 484.89. | |
| (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-chloro-4-methyltetrahydrofuran-3-yl benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxopyrimidine-1(2H)-yl)-2-((benzoyloxy)methyl)-4-Chloro-4-methyltetrahydrofuran-3-ylbenzoate. Grade: 95%. CAS No. 1496551-70-2. Molecular formula: C31H26ClN3O7. Mole weight: 588.01. | |
| (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-hydroxy-4-methyltetrahydrofuran-3-yl benzoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grade: 95%. CAS No. 863329-64-0. Molecular formula: C31H27N3O8. Mole weight: 569.56. | |
| (2S)-Isopropyl 2-(((perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate | An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Propan-2-yl (2S)-2-{[pentafluorophenoxy(phenoxy)phosphoryl]amino}propanoate; N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester; N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine1-methylethyl ester. CAS No. 1256490-52-4. Molecular formula: C18H17F5NO5P. Mole weight: 453.302. | |
Our database is helping our users find suppliers everyday.
