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Sofosbuvir. CAS No. 1190307-88-0. Product ID: 8-04873. Molecular formula: C22H29FN3O9P. Mole weight: 529.45. Properties: ex Melaleuca alternifolia.
Sofosbuvir
Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC 50 of 92 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-7977; PSI-7977. CAS No. 1190307-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15005.
Sofosbuvir
Sofosbuvir (GS-7977) is an HCV RNA replication inhibitor with an EC50 of 92 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SOFOSBUVIR;PSI-7977;SOVALDI;1190307-88-0;GS-7977;PSI 7977;UNII-WJ6CA3ZU8B;GS7977;WJ6CA3ZU8B;CHEBI:85083;Sofosbuvir [USAN:INN];C22H29FN3O9P;Hepcinat;Hepcvir;Resof;SoviHep;HSDB 8226;PSI7977;Sovaldi (TN);Sofosbuvir (PSI-7977, GS-7977);Sofosbuvir (JAN/USAN);Sofosbuvir(PSI-7977);2-((5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-ylmethoxy)phenoxyphosphorylamino. Product Category: Inhibitors. Appearance: Solid. CAS No. 1190307-88-0. Molecular formula: C22H29FN3O9P. Mole weight: 529.5g/mol. Purity: 0.9993. IUPACName: propan-2-yl (2S)-2-[[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate. Canonical SMILES: CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3. Product ID: ACM1190307880. Alfa Chemistry ISO 9001:2015 Certified.
Sofosbuvir
Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Uses: Antiviral agents. Synonyms: PSI-7977; PSI 7977; PSI7977; GS7977; GS-7977; GS 7977; Sovaldi; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine, 1-methylethyl ester; Hepcinat; Hepcvir; Resof; SoviHep. Grades: >98%. CAS No. 1190307-88-0. Molecular formula: C22H29FN3O9P. Mole weight: 529.45.
Sofosbuvir 3',5'-Bis-(S)-phosphate
Sofosbuvir 3',5'-Bis-(S)-phosphate, an impurity of PSI-7977, which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: (2S)-Isopropyl 2- ( ( ( ( (2R, 3R, 4R, 5R)-5- (2, 4-Dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-fluoro-2- ( ( ( (R)- ( ( (S)-1-isopropoxy-1-oxopropan-2-yl)amino) (phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy) (phenoxy)phosphoryl)amino)propanoate. Grades: 98.77%. CAS No. 1337482-17-3. Molecular formula: C34H45FN4O13P2. Mole weight: 798.69.
Sofosbuvir α-Isomer
As a derivative compound of Sofosbuvir, Sofosbuvir α-Isomer is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have shown PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: (S)-Isopropyl 2- ( ( (S)- ( ( (2R, 3R, 4R, 5S)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy) (phenoxy)phosphoryl)amino)propanoate. Molecular formula: C22H29FN3O9P. Mole weight: 529.45.
Sofosbuvir Carboxylic Acid
As an impurity of Sofosbuvir, Sofosbuvir Carboxylic Acid is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: (S)-2- ( ( (S)- ( ( (2R, 3R, 4R, 5R)-5- (2, 4-Dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy) (phenoxy)phosphoryl)amino)propanoic Acid. Molecular formula: C19H23FN3O9P. Mole weight: 487.37.
Sofosbuvir Impurity 1
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2R,3R,4S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate; N4,3',5'-Tribenzoyl,2'-deoxy-2'β-fluoro-2'C-α-methyl Cytidine. Grades: > 95%. Molecular formula: C31H26FN3O7. Mole weight: 571.55.
Sofosbuvir Impurity 10
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Uridine, 2'-deoxy-2'-methylene-, 3',?5'-dibenzoate. Grades: > 95%. CAS No. 1910099-17-0. Molecular formula: C24H20N2O7. Mole weight: 448.42.
Sofosbuvir Impurity 11
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-epi-Sofosbuvir Desphosphate. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 12
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-c-methyl arabino-uridine; 1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: > 95%. CAS No. 114262-49-6. Molecular formula: C10H14N2O6. Mole weight: 258.23.
Sofosbuvir Impurity 13
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Methylene-2'-deoxyuridine; 2'-Methylidene-2'-deoxyuridine; 2'-Deoxy-2'-methyleneuridine. Grades: > 95%. CAS No. 119410-95-6. Molecular formula: C10H12N2O5. Mole weight: 240.22.
Sofosbuvir Impurity 14
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 15
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Defluro-2'-hydroxy 2'-epi-Sofosbuvir. Grades: > 95%. Molecular formula: C22H30N3O10P. Mole weight: 527.46.
Sofosbuvir Impurity 15
Sofosbuvir Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1334513-02-8. Molecular formula: C18H17F5NO5P. Mole weight: 453.3. Catalog: APB1334513028.
Sofosbuvir Impurity 16
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Defluro-2'-methylene Sofosbuvir. Grades: > 95%. Molecular formula: C22H28N3O9P. Mole weight: 509.45.
Sofosbuvir Impurity 17
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C34H45FN4O13P2. Mole weight: 798.7.
Sofosbuvir Impurity 2
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Benzamide, N-[1-(3,5-di-O-benzoyl-2-C-methyl-beta-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-. Grades: > 95%. CAS No. 863329-62-8. Molecular formula: C31H27N3O8. Mole weight: 569.56.
Sofosbuvir Impurity 20
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2S)-Isopropyl 2- ( ( ( ( (2R, 3R, 4R, 5R) -5- (2, 4-Dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-2- (hydroxymethyl) -4-methyltetrahydrofuran-3-yl) oxy) (phenoxy) phosphoryl) amino) propanoate; Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]. Grades: > 95%. CAS No. 1337482-15-1. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 21
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Chloro (R)-Phosphoryl Sofosbuvir. Grades: > 95%. CAS No. 1496552-50-1. Molecular formula: C22H29ClN3O9P. Mole weight: 545.92.
Sofosbuvir Impurity 22 (GS-491241)
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 23
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: α-Sofosbuvir Desphosphate. Grades: 98%. CAS No. 2041584-99-8. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 24
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 25
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 25
Sofosbuvir Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1015073-43-4. Molecular formula: C10H14FN2O8P. Mole weight: 340.2. Catalog: APB1015073434.
Sofosbuvir Impurity 26
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 26
Sofosbuvir Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1859162-80-3. Molecular formula: C16H18FN2O8P. Mole weight: 416.3. Catalog: APB1859162803.
Sofosbuvir Impurity 27
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 28
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 29
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: ent-Sofosbuvir Desphosphate. Grades: 98%. CAS No. 1946820-96-7. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 3
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C38H31N3O9. Mole weight: 673.69.
Sofosbuvir Impurity 31
PSI-7409, the active 5'-triphosphate metabolite of PSI-7851, is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Synonyms: PSI-7409; PSI 7409; PSI7409; [[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate. Grades: > 95%. CAS No. 1015073-42-3. Molecular formula: C10H16FN2O14P3. Mole weight: 500.16.
Sofosbuvir Impurity 32
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, γ-lactone, 3,?5-dibenzoate, (2S)?-. Grades: > 95%. CAS No. 1157884-58-6. Molecular formula: C20H17FO6. Mole weight: 372.34.
Sofosbuvir Impurity 33
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: D-erythro-Pentonic acid, 2-chloro-2-deoxy-2-methyl-, γ-lactone, 3,?5-dibenzoate, (2R)?-. Grades: > 95%. CAS No. 1496551-65-5. Molecular formula: C20H17ClO6. Mole weight: 388.8.
Sofosbuvir Impurity 34 (GS-606965)
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 5'-Uridylic acid, 2'-deoxy-2'-fluoro-2'-methyl-, (2'R)?-; (2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylic acid; PSI 7411. Grades: > 95%. CAS No. 1015073-43-4. Molecular formula: C10H14FN2O8P. Mole weight: 340.2.
Sofosbuvir Impurity 35
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2'R)-2'-Chloro-2'-deoxy-2'-methyl-uridine; Chloro Sofosbuvir Desphosphate. Grades: > 95%. CAS No. 1496551-72-4. Molecular formula: C10H13ClN2O5. Mole weight: 276.68.
Sofosbuvir Impurity 35
Sofosbuvir Impurity 35. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1233335-82-4. Molecular formula: C16H25FN3O9P. Mole weight: 453.36. Catalog: APB1233335824.
Sofosbuvir Impurity 36
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C10H15FN2O11P2. Mole weight: 420.18.
Sofosbuvir Impurity 37 ( Sofosbuvir Isomer)
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 38
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 39
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Benzamide, N-[1-[(2R)?-3,?5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]?-1,?2-dihydro-2-oxo-4-pyrimidinyl]?-; N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide. Grades: 98%. CAS No. 874638-94-5. Molecular formula: C31H26FN3O7. Mole weight: 571.55.
Sofosbuvir Impurity 4
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: N-Benzoyl-2'-deoxy-2'-methylenecytidine 3',5'-Dibenzoate; N4,3',5'-Tribenzoyl,2'-deoxy-2'-methylene Cytidine. Grades: > 95%. CAS No. 863329-63-9. Molecular formula: C31H25N3O7. Mole weight: 551.56.
Sofosbuvir Impurity 40
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Des-alanyl Sofosbuvir. Grades: > 95%. Molecular formula: C16H18FN2O8P. Mole weight: 416.29.
Sofosbuvir Impurity 41
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-1-(1-methylethyl) Ester L-Alanine; O-Desphenyl Sofosbuvir. Grades: > 95%. CAS No. 1233335-82-4. Molecular formula: C16H25FN3O9P. Mole weight: 453.36.
Sofosbuvir Impurity 42
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C16H25FN3O9P. Mole weight: 453.36.
Sofosbuvir Impurity 43
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: N-(Hydroxyphenoxyphosphinyl)-L-alanine 1-Methylethyl Ester Sodium Salt; (2S)-Isopropyl 2- ( (Hydroxy (phenoxy)phosphoryl)amino)propanoate Sodium Salt; Isopropyl N-(Hydroxyphenoxyphosphinyl)alaninate Sodium Salt. Grades: > 95%. Molecular formula: C12H17NO5P. Na. Mole weight: 286.25 22.99.
Sofosbuvir Impurity 5
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C24H22FN3O6. Mole weight: 467.46.
Sofosbuvir Impurity 6
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C24H22FN3O6. Mole weight: 467.46.
Sofosbuvir Impurity 7
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C24H21FN2O7. Mole weight: 468.44.
Sofosbuvir Impurity 8
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Uridine, 2'-C-methyl-, 3',?5'-dibenzoate. Grades: > 95%. CAS No. 944476-44-2. Molecular formula: C24H22N2O8. Mole weight: 466.44.
Sofosbuvir Impurity 8
Sofosbuvir Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1337482-15-1. Molecular formula: C22H29FN3O9P. Mole weight: 529.46. Catalog: APB1337482151.
Sofosbuvir Impurity 9
Sofosbuvir Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1337482-17-3. Molecular formula: C34H45FN4O13P2. Mole weight: 798.69. Catalog: APB1337482173.
Sofosbuvir impurity C
An impurity of Sofosbuvir, a medication used to treat hepatitis C. Synonyms: Sofosbuvir impurity A; (2R)-isopropyl 2- ( ( ( ( (2R, 3R, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy) (phenoxy)phosphoryl)amino)propanoate. CAS No. 1496552-28-3. Molecular formula: C22H29FN3O9P. Mole weight: 529.5.
Sofosbuvir Impurity (GS-566500)
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: L-Alanine, N-[(2'R)?-2'-deoxy-2'-fluoro-2'-methyl-5'-uridylyl]?-; N-[(2'R)-2'-Deoxy-2'-fluoro-2'-methyl-5'-uridylyl]-L-alanine; PSI 352707. Grades: > 95%. CAS No. 1233335-78-8. Molecular formula: C13H19FN3O9P. Mole weight: 411.28.
Sofosbuvir (PSI-7977, GS-7977)
PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Group: Biochemicals. Alternative Names: Isopropyl (2S) -2- [ [ [ (2R, 3R, 4R, 5R) -5- (2, 4-dioxopyrimidin-1-yl) -4-fluoro-3-hydroxy-4-methyl-tetrahydrofuran-2-yl] methoxy-phenoxy-phosphoryl] amino] propanoate; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-1-methylethyl Ester L-Alanine; GS-7977; PSI-7977. Grades: Highly Purified. CAS No. 1190307-88-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg. Molecular Formula: C22H29FN3O9P, Molecular Weight: 529.45. US Biological Life Sciences.
Worldwide
Sofosbuvir (R)-Phosphate
Sofosbuvir (R)-Phosphate. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS003089. Format: Neat.
2-Defluro-2-hydroxy 2-epi-Sofosbuvir
2-Defluro-2-hydroxy 2-epi-Sofosbuvir is an impurity of Sofosbuvir (P839640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H30N3O10P, Molecular Weight: 527.46. US Biological Life Sciences.
Worldwide
2-Defluro-2-hydroxy 2-epi-Sofosbuvir-13Cd3
2-Defluro-2-hydroxy 2-epi-Sofosbuvir-13Cd3 is the labelled form of 2-Defluro-2-hydroxy 2-epi-Sofosbuvir (D228775), which is an impurity of Sofosbuvir (P839640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C2113CH27D3N3O10P, Molecular Weight: 531.47. US Biological Life Sciences.
Worldwide
2-Defluro-2-methylene Sofosbuvir
2-Defluro-2-methylene Sofosbuvir is an impurity of Sofosbuvir (P839640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H28N3O9P, Molecular Weight: 509.45. US Biological Life Sciences.
Worldwide
2'-epi-Sofosbuvir Desphosphate
2'-epi-Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
2-epi-Sofosbuvir Desphosphate
2-epi-Sofosbuvir Desphosphate is possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H13FN2O5, Molecular Weight: 260.22. US Biological Life Sciences.
Worldwide
3'-O-Benzyl Sofosbuvir Desphosphate
3'-O-Benzyl Sofosbuvir Desphosphate may be a metabolite of Sofosbuvir, a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: 1-((2R,3R,4R,5R)-4-(Benzyloxy)-3-fluoro-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Molecular formula: C17H19FN2O5. Mole weight: 350.34.
5'O-Benzyl Sofosbuvir Desphosphate
5'O-Benzyl Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Synonyms: 5'-O-Benzyl RO 2433. Molecular formula: C17H19FN2O5. Mole weight: 350.34.
α-Sofosbuvir Desphosphate
As a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate, α-Sofosbuvir Desphosphate is a possible metabolite of Sofosbuvir is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Chloro Sofosbuvir
Chloro Sofosbuvir is an impurity of Sofosbuvir; a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled Sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. Synonyms: N-[[P(S),2'R]-2'-Chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-Methylethyl Ester. Grades: ≥98% (HPLC). CAS No. 1496552-51-2. Molecular formula: C22H29ClN3O9P. Mole weight: 545.91.
ent-Sofosbuvir Desphosphate
ent-Sofosbuvir Desphosphate is a possible metabolite of prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-((2R,3R,4R,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a powerful antimicrobial agent, is renowned for its efficacy in treating a range of bacterial and fungal infections, including those caused by Candida, Aspergillus, and Cryptococcus species. This pharmaceutical marvel works by clobbering the synthesis of crucial nucleic acids in microbes to sabotage their survival. Notably, its phenomenal antibacterial and antifungal activity renders it an essential tool in the battle against streptococcal and staphylococcal infections. Synonyms: Sofosbuvir impurity SA15432. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt
PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), inhibiting HCV NS5B polymerases, with IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively. Synonyms: PSI-7409 (tetrasodium);tetrasodium; [[[(2R,3R,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-3-hydroxy-4-methyloxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate. Grades: ≥98% (HPLC). CAS No. 1621884-22-7. Molecular formula: C10H12FN2Na4O14P3. Mole weight: 588.09.
(2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine
PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Synonyms: RO-2433; RO 2433; RO2433; PSI6206; PSI 6206; PSI-6206; GS331007; GS-331007; GS 331007; 2'-Deoxy-2'-fluoro-2'-C-methyluridine; Sofosbuvir Metabolite GS331007; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: ≥95%. CAS No. 863329-66-2. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
(2'R)?-2'-?Deoxy-?2'-?fluoro-?2'-?methyl-uridine 5'-?Triphosphate Triethylammonium Salt
(2'R)?-2'-?Deoxy-?2'-?fluoro-?2'-?methyl-uridine 5'-?Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro- β-C-methyluridine-5'-monophosphate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C28H61FN5O14P3. US Biological Life Sciences.
Worldwide
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