Sorafenib Suppliers USA
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Product | Description | |
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Sorafenib Quick inquiry Where to buy Suppliers range | Sorafenib Inhibitor. Uses: Scientific use. Product Category: T0093L. CAS No. 284461-73-0. | |
Sorafenib 2-Chloro Isomer Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4- [4- [ [ [ [2-Chloro-3- (trifluoromethyl) ?phenyl] ?amino] ?carbonyl] ?amino] ?phenoxy] ?-N-methyl-2-pyridinecarboxamide; 4-Deschloro-2-chloro-Sorafenib. Grades: > 95%. CAS No. 1431697-81-2. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.83. | |
Sorafenib-beta-D-Glucuronide Quick inquiry Where to buy Suppliers range | Sorafenib-beta-D-Glucuronide is one of Sorafenib metabolites. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamoyl]-beta-D-glucopyranuronosylamine; 1- [ [4-Chloro-3- (trifluoroMethyl) phenyl] [ [ [4- [ [2- [ (MethylaMino) carbonyl] -4-pyridinyl] oxy] phenyl] aMino] carbonyl] aMino] -1-deoxy-Beta-D-glucopyranuronic Acid; Sorafenib Beta-D-Glucuronide. Grades: ≥95%. CAS No. 1130164-93-0. Molecular formula: C27H24ClF3N4O9. Mole weight: 640.95. | |
Sorafenib-d3 Quick inquiry Where to buy Suppliers range | Sorafenib-d3. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. CAS No. 1130115-44-4. IUPAC Name: 4-[4-[[4-chloro-3- (trifluoromethyl) phenyl]carbamoylamino]phenoxy]-N- (trideuteriomethyl) pyridine-2-carboxamide. Molecular formula: C212H3H13ClF3N4O3. Mole weight: 467.84. Catalog: APS1130115444. SMILES: [2H]C ([2H]) ([2H])NC (=O)c1cc (Oc2ccc (NC (=O)Nc3ccc (Cl)c (c3)C (F) (F)F)cc2)ccn1. Format: Neat. Product Type: Stable Isotope Labelled. | |
Sorafenib-d3 Quick inquiry Where to buy Suppliers range | Cas No. 1130115-44-4. | |
Sorafenib Hemitosylate Quick inquiry Where to buy Suppliers range | Sorafenib Hemitosylate is the salt of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino] phenoxy]-N-methyl-2-pyridinecarboxamide, 4-methylbenzenesulfonate (2:1). CAS No. 2056030-06-7. Molecular formula: C21H16ClF3N4O3.1/2(C7H8O3S). Mole weight: 550.92. | |
Sorafenib Impurity 1 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 1 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C28H25N7O6. Mole weight: 555.54. | |
Sorafenib Impurity 10 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 10 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: SORAFENIB IMPURITY 10; 2206827-14-5; propan-2-yl N-[4-[2-(methylcarbamoyl)pyridin-4-yl]oxyphenyl]carbamate; SORAFENIBIMPURITY10; EN300-6494528; Z3064469246; Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate; propan-2-yl N-(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamate. Molecular formula: C24H24F3N5O4. Mole weight: 503.47. | |
Sorafenib Impurity 4 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 4 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C7H7NO2. Mole weight: 137.14. | |
Sorafenib Impurity 5 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 5 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C14H13ClN4O2. Mole weight: 304.73. | |
Sorafenib Impurity 7 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 7 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-Hydroxy-phenylhydroxylamine. Grades: ≥ 95%. CAS No. 3505-87-1. Molecular formula: C6H7NO2. Mole weight: 125.13. | |
Sorafenib Impurity 8 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 8 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: Flucofuron; 370-50-3; Flucofuron [ISO]; TCMDC-137559; 1,3-bis[4-chloro-3-(trifluoromethyl)phenyl]urea; CHEBI:59242; 1,3-Bis(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)urea; 1,3-bis(4-chloro-3-(trifluoromethyl)phenyl)urea; N,N'-bis[4-chloro-3-(trifluoromethyl)phenyl]urea; U3V3S70655; Mitin N; 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea; N,N'-BIS(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREA. Molecular formula: C25H25F3N6O3. Mole weight: 514.50. | |
Sorafenib Impurity 9 Quick inquiry Where to buy Suppliers range | Sorafenib Impurity 9 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4- (4- (3- (4-Hydroxy-3- (trifluoromethyl) phenyl) ureido) phenoxy) -N-methylpicolinamide. CAS No. 862875-16-9. Molecular formula: C21H17F3N4O4. Mole weight: 446.38. | |
Sorafenib impurity B Quick inquiry Where to buy Suppliers range | Sorafenib impurity B. CAS No. 370-50-3. | |
Sorafenib Impurity C Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Grades: > 95%. Molecular formula: C27H23N5O6. Mole weight: 513.51. | |
Sorafenib Impurity I Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 1,3-bis-(4-Chloro-α,α,α-trifluoro-m-tolyl)urea. Grades: > 95%. CAS No. 370-50-3. Molecular formula: C15H8Cl2F6N2O. Mole weight: 417.13. | |
Sorafenib-methyl-d3 Quick inquiry Where to buy Suppliers range | Labeled Sorafenib, a potent Raf kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Sorafenib N-oxide Quick inquiry Where to buy Suppliers range | Sorafenib N-oxide. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] phenoxy] -N-methyl-2-pyridinecarboxamide 1-oxide. Grades: Highly Purified. CAS No. 583840-03-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H16ClF3N4O4. US Biological Life Sciences. | Worldwide |
Sorafenib-N-oxide Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Uses: Protein kinase inhibitors. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide 1-oxide. Grades: > 95%. CAS No. 583840-03-3. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.82. | |
Sorafenib N-Oxide Quick inquiry Where to buy Suppliers range | Sorafenib N-Oxide. Uses: For analytical and research use. Group: Enzyme Activators, Inhibitors & Substrates. Alternative Names: 4-[4-[[4-Chloro-3- (trifluoromethyl) phenyl]carbamoylamino]phenoxy]-N-methyl-1-oxido-pyridin-1-ium-2-carboxamide, Sorafenib N-Oxide,2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-, 1-oxide. CAS No. 583840-03-3. IUPAC Name: 4-[4-[[4-chloro-3- (trifluoromethyl) phenyl]carbamoylamino]phenoxy]-N-methyl-1-oxidopyridin-1-ium-2-carboxamide. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.82. Catalog: APS583840033. SMILES: CNC (=O)c1cc (Oc2ccc (NC (=O)Nc3ccc (Cl)c (c3)C (F) (F)F)cc2)cc[n+]1[O-]. Format: Neat. | |
Sorafenib Phenyl Carbamate Quick inquiry Where to buy Suppliers range | Sorafenib Phenyl Carbamate. CAS No. 871555-75-8. | |
Sorafenib, p-Toluenesulfonate Salt Quick inquiry Where to buy Suppliers range | Sorafenib (Bay 43-9006) is a novel bi-aryl urea compound that inhibits cell proliferation by targeting the ERK pathway and angiogenesis by targeting the receptor tyrosine kinases VEGFR-2 and PDGFR-b and their associated signaling cascades. Although sorafenib was initially developed as a Raf kinase inhibitor (IC50=6nM), it has since been shown to have activity against many receptor tyrosine kinases involved in tumorigenesis and angiogenesis including FGFR-1, wt BRAF and V599E mutant BRAF, as well as members of the so-called "split kinase" family: VEGFR-2, VEGFR-3, PDGFR-b, c-KIT, and Flt3. However, sorafenib is not active against erbB1, erbB2, ERK-1, MEK-1, EGFR, HER-2, IGFR-1, c-MET, c-yes, PKB, PKA, cdk1/cyclinB, PKC, and pim-1. In cellular mechanistic assays, sorafenib decreased basal phosphorylation of the ERK pathway in melanoma, breast, colon, and pancreatic tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 475207-59-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C21H16ClF3N4O3 C7H8O3S, Molecular Weight: 637.03. US Biological Life Sciences. | Worldwide |
Sorafenib Related Compound Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-methyl-4-phenoxy-2-Pyridinecarboxamide. Grades: > 95%. CAS No. 2004659-85-0. Molecular formula: C13H12N2O2. Mole weight: 228.25. | |
Sorafenib related compound 10 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxylic Acid; 4- (4- (3- (4-Chloro-3- (trifluoromethyl) phenyl) ureido) phenoxy) picolinic Acid; Sorafenib Hydroxydemethylamine. Grades: > 95%. CAS No. 1012058-78-4. Molecular formula: C20H13ClF3N3O4. Mole weight: 451.79. | |
Sorafenib related compound 11 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-Methyl-4-[4-[[2-[(methylamino)carbonyl]-4-pyridinyl]amino]phenoxy]-2-pyridinecarboxamide. Grades: > 95%. CAS No. 2004659-83-8. Molecular formula: C20H19N5O3. Mole weight: 377.40. | |
Sorafenib Related Compound 12 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-(formylamino)phenoxy]-N-methyl-2-Pyridinecarboxamide. Grades: > 95%. CAS No. 2004659-84-9. Molecular formula: C14H13N3O3. Mole weight: 271.27. | |
Sorafenib Related Compound 13 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 6-Chloro-N-methylpicolinamide; 6-Chloro-N-methyl-2-pyridinecarboxamide. Grades: > 95%. CAS No. 845306-04-9. Molecular formula: C7H7ClN2O. Mole weight: 170.6. | |
Sorafenib Related Compound 14 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide; BAY 43-9007; N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-(2-carbamoyl-4-pyridyloxy)phenyl]urea; N-Desmethyl Sorafenib. Grades: > 95%. CAS No. 284461-74-1. Molecular formula: C20H14ClF3N4O3. Mole weight: 450.81. | |
Sorafenib Related Compound 15 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4,4'-[Carbonylbis(imino-4,1-phenyleneoxy)]bis[N-methyl-2-pyridinecarboxamide]; PAPE-urea; N,N'-Bis[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea. Grades: > 95%. CAS No. 284670-98-0. Molecular formula: C27H24N6O5. Mole weight: 512.53. | |
Sorafenib related compound 2 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]carbamic Acid Ethyl Ester; [4-Chloro-3-(trifluoromethyl)phenyl]carbamic Acid Ethyl Ester; 4-Chloro-3-(trifluoromethyl)carbanilic Acid Ethyl Ester; Ethyl (4-Chloro-3-(trifluoromethyl)phenyl)carbamate. Grades: > 95%. CAS No. 18585-06-3. Molecular formula: C10H9ClF3NO2. Mole weight: 267.64. | |
Sorafenib Related Compound 26 HCl Quick inquiry Where to buy Suppliers range | Sorafenib Related Compound 26 HCl is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C11H11F3N2O2.HCl. Mole weight: 296.67. | |
Sorafenib related compound 3 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-Methyl-4-[4-[[[[3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide; Deschloro Sorafenib. Grades: > 95%. CAS No. 1285533-84-7. Molecular formula: C21H17F3N4O3. Mole weight: 430.39. | |
Sorafenib related compound 5 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Grades: > 95%. Molecular formula: C14H16N4O2. Mole weight: 272.31. | |
Sorafenib related compound 8 Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 2-Pyridinecarboxamide, 4-[4-[(aminocarbonyl)?amino]?phenoxy]?-N-methyl-. Grades: > 95%. CAS No. 1129683-88-0. Molecular formula: C14H14N4O3. Mole weight: 286.29. | |
Sorafenib tosylate Quick inquiry Where to buy Suppliers range | Sorafenib tosylate. Group: Heterocyclic Organic Compound. Grades: 96%. CAS No. 4750207-59-1. Product ID: ACM4750207591. | |
Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib Quick inquiry Where to buy Suppliers range | Des-(4-chloro-3-trifluoromethyl)-4-(methyl-4-hydroxypicolinate) Sorafenib is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4- [4- [ [ [ [4- [ [2- [ (Methylamino) carbonyl] -4-pyridinyl] oxy] phenyl] amino] carbonyl] amino] phenoxy] -methyl ester-2-pyridinecarboxylic Acid; Sorafenib Impurity C; Sorafenib Impurity 6. Grades: > 98%. CAS No. 2204442-52-2. Molecular formula: C27H23N5O6. Mole weight: 513.50. | |
N-Desmethyl Sorafenib (Pyridine)-N-oxide Quick inquiry Where to buy Suppliers range | N-Desmethyl Sorafenib (Pyridine)-N-oxide is one of Sorafenib metabolites. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide 1-Oxide; BAY 68-7769; N'-desmethylsorafenib N-oxide; N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-{4-[2-carbamoyl-1-oxo-(4-pyridyloxy)]phenyl}urea. Grades: 98%. CAS No. 583840-04-4. Molecular formula: C20H14ClF3N4O4. Mole weight: 466.80. | |
1,3-Bis(6-chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea Quick inquiry Where to buy Suppliers range | 1,3-Bis(6-chloro-2',3'-difluoro-[1,1'-biphenyl]-3-yl)urea is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C25H14Cl2F4N2O. Mole weight: 505.29. | |
1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea Quick inquiry Where to buy Suppliers range | 1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is an impurity of Sorafenib (S676850), a kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1129683-83-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H10ClF3N2O2, Molecular Weight: 330.69. US Biological Life Sciences. | Worldwide |
1- (4-Chloro-3- (trifluoromethyl) phenyl) urea Quick inquiry Where to buy Suppliers range | 1- (4-Chloro-3- (trifluoromethyl) phenyl) urea is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C8H6ClF3N2O, Molecular Weight: 238.59. US Biological Life Sciences. | Worldwide |
1-(4-Chloro-3-(trifluoromethyl)phenyl)urea Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]urea; Sorafenib Impurity 1; Sorafenib related compound 1; 1-[3-(Trifluoromethyl)-4-chlorophenyl]urea; Sorafenib Related Compound 9. Grades: > 95%. CAS No. 343247-69-8. Molecular formula: C8H6ClF3N2O. Mole weight: 238.59. | |
3-? (Trifluoromethyl) ?phenyl Isocyanate Quick inquiry Where to buy Suppliers range | 3-? (Trifluoromethyl) ?phenyl Isocyanate is a reagent used in the synthesis of heme-regulated inhibitor as selective activators of the eukaryotic inhibition factor Alpha (eIF2α) phosphorylation arm of the endoplasmic reticulum stress response. Influences cell proliferation, cell differentiaton and adaptation to stress. Also a reagent in the preparation of sorafenib derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 329-01-1. Pack Sizes: 500mg, 1g. Molecular Formula: C8H4F3NO, Molecular Weight: 187.12. US Biological Life Sciences. | Worldwide |
4-(4-Aminophenoxy)-2-pyridinecarboxamide Quick inquiry Where to buy Suppliers range | 4-(4-Aminophenoxy)-2-pyridinecarboxamide is one of Sorafenib intermediates. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-(2-Carbamoyl-4-pyridyloxy)aniline; 4-(4-Aminophenoxy)picolinamide; 4-(4-amino-phenoxy)-pyridine-2-carboxylic acid amide; 2-Pyridinecarboxamide, 4-(4-aminophenoxy)-; Sorafenib tosylate Impurity 8; 4-(2-carbamoyl-pyridin-4-yloxy)aniline. Grades: 95%. CAS No. 284462-80-2. Molecular formula: C12H11N3O2. Mole weight: 229.23. | |
4-(4-Aminophenoxy)picolinic Acid Quick inquiry Where to buy Suppliers range | 4-(4-Aminophenoxy)picolinic Acid is used in the synthesis of sorafenib analogs. Synonyms: 4-(4-Aminophenoxy)-2-pyridinecarboxylic Acid; Sorafenib Related Compound 19. Grades: 98%. CAS No. 1012058-77-3. Molecular formula: C12H10N2O3. Mole weight: 230.22. | |
4-Chloro-3-(trifluoromethyl)aniline Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-chloro-3-(trifluoromethyl)aniline. Grades: 97 %. CAS No. 320-51-4. Molecular formula: C7H5ClF3N. Mole weight: 195.57. | |
4-Chloro-N-ethyl-2-pyrimidinamine Quick inquiry Where to buy Suppliers range | 4-Chloro-N-ethyl-2-pyrimidinaminee is used as a reactant in the preparation of sorafenib analogs. Synonyms: 4-Chloro-2-(ethylamino)pyrimidine; N-(4-Chloropyrimidin-2-yl)-N-ethylamine; N-(4-Chloropyrimidin-2-yl)ethylamine; 2-(4-Chloropyrimidin-2-yl)ethanamine. Grades: ≥95%. CAS No. 86575-65-7. Molecular formula: C6H8ClN3. Mole weight: 157.60. | |
4-Chloro-N,N-dimethyl-pyridine-2-carboxamide Quick inquiry Where to buy Suppliers range | 114780-06-2, 4-Chloro-N,N-dimethylpicolinamide, 4-chloro-N,N-dimethylpyridine-2-carboxamide, 4-Chloro-N,N-dimethyl-pyridine-2-carboxamide, SCHEMBL621293, DTXSID70407042, MFCD06655680, AKOS008999236, BS-14474, 3-[3-(Dimethylamino)propoxy]benzylalcohol, 4-chloro-N,N-dimethyl-2-pyridinecarboxamide, CS-0164187, FT-0645747, EN300-13131, 2-Pyridinecarboxamide, 4-chloro-N,N-dimethyl-, D84243, 4-Chloro-pyridine-2-carboxylic acid dimethylamide, A803235, Z89269017, F8881-2464, 4-Chloro-N,N-dimethylpicolinamide? (Sorafenib Impurity pound(c). | |
AMG 925 Quick inquiry Where to buy Suppliers range | AMG-925 is a potent, selective, and bioavailable FLT3/cyclin-dependent kinase 4 (CDK4) dual kinase inhibitor. AMG 925 inhibited AML xenograft tumor growth by 96% to 99% without significant body weight loss. The antitumor activity of AMG 925 correlated with the inhibition of STAT5 and RB phosphorylation, the pharmacodynamic markers for inhibition of FLT3 and CDK4, respectively. In addition, AMG 925 was also found to inhibit FLT3 mutants (e.g., D835Y) that are resistant to the current FLT3 inhibitors (e.g., AC220 and sorafenib). AMG 925, which combines inhibition of two kinases essential for proliferation and survival of FLT3-mutated AML cells, may improve and prolong clinical responses. Synonyms: AMG925; AMG-925; AMG 925; FLX925; FLX-925; FLX 925. Grades: >98%. CAS No. 1401033-86-0. Molecular formula: C26H29N7O2. Mole weight: 471.55. | |
Angiogenesis related Compound Library Quick inquiry Where to buy Suppliers range | A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); - Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc. ; - Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L4800. Categories: Angiogenesis related Compounds Libraries. | |
BAY-721973 Quick inquiry Where to buy Suppliers range | BAY-721973 is a bio-active chemical,but few detailed information has been published yet. Synonyms: BAY-721973; BAY 721973; BAY721973; Sorafenib metabolite M3; UNII-83F1Z938Q0; 4- (4- ( ( ( (4-chloro-3- (trifluoromethyl) phenyl) amino) carbonyl) amino) phenoxy) -N- (hydroxymethyl) -2-Pyridinecarboxamide. Grades: 98%. CAS No. 1380310-94-0. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.83. | |
Ethyl (4-((2-(Methylcarbamoyl)pyridin-4-yl)oxy)phenyl)carbamate Quick inquiry Where to buy Suppliers range | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: PAPE-ethyl Carbamate; Sorafenib related compound 7. Grades: > 98%. CAS No. 2206827-12-3. Molecular formula: C16H17N3O4. Mole weight: 315.32. | |
Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate Quick inquiry Where to buy Suppliers range | Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: Sorafenib related compound 6. Grades: > 95%. Molecular formula: C17H19N3O4. Mole weight: 329.35. | |
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Quick inquiry Where to buy Suppliers range | N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: Sorafenib Impurity 3. Grades: 98%. CAS No. 1129683-83-5. Molecular formula: C14H10ClF3N2O2. Mole weight: 330.69. | |
N,N'-bis[3-(4-Cyanophenoxy)-4-methylphenyl]urea Quick inquiry Where to buy Suppliers range | N,N'-bis[3-(4-Cyanophenoxy)-4-methylphenyl]urea is a derivative of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: Urea, N,N'-bis[3-(4-cyanophenoxy)-4-methylphenyl]-. Grades: 98%. CAS No. 1421677-31-7. Molecular formula: C29H22N4O3. Mole weight: 474.51. | |
Phenyl (2-Chloro-3-(trifluoromethyl)phenyl)carbamate Quick inquiry Where to buy Suppliers range | Phenyl (2-Chloro-3-(trifluoromethyl)phenyl)carbamate is one of Sorafenib intermediates. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. CAS No. 2518227-67-1. Molecular formula: C14H9ClF3NO2. Mole weight: 315.67. | |
Regorafenib Quick inquiry Where to buy Suppliers range | Inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] -3-fluorophenoxy] -N-methyl-2-pyridinecarboxamide; 4-[4-[N- (4-Chloro-3-trifluoromethylphenyl) ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; BAY 73-4506; Fluoro-Sorafenib; Stivarga. Grades: Highly Purified. CAS No. 755037-03-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 482.82. US Biological Life Sciences. | Worldwide |