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Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC 50 s of 6 nM and 20 nM for Raf-1 and B-Raf , respectively. Sorafenib is a multikinase inhibitor with IC 50 s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2 , VEGFR3 , PDGFRβ , FLT3 and c-Kit , respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bay 43-9006. CAS No. 284461-73-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-10201.
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4- [4- [ [ [ [2-Chloro-3- (trifluoromethyl) ?phenyl] ?amino] ?carbonyl] ?amino] ?phenoxy] ?-N-methyl-2-pyridinecarboxamide; 4-Deschloro-2-chloro-Sorafenib. Grades: > 95%. CAS No. 1431697-81-2. Molecular formula: C21H16ClF3N4O3. Mole weight: 464.83.
Sorafenib β-D-Glucuronide
Sorafenib β-D-Glucuronide. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1130164-93-0. Molecular Formula: C27H24ClF3N4O9. Mole Weight: 640.95. Catalog: APB1130164930.
Sorafenib-beta-D-Glucuronide
Sorafenib-beta-D-Glucuronide is one of Sorafenib metabolites. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamoyl]-beta-D-glucopyranuronosylamine; 1- [ [4-Chloro-3- (trifluoroMethyl) phenyl] [ [ [4- [ [2- [ (MethylaMino) carbonyl] -4-pyridinyl] oxy] phenyl] aMino] carbonyl] aMino] -1-deoxy-Beta-D-glucopyranuronic Acid; Sorafenib Beta-D-Glucuronide. Grades: ≥95%. CAS No. 1130164-93-0. Molecular formula: C27H24ClF3N4O9. Mole weight: 640.95.
Sorafenib Hemitosylate is the salt of Sorafenib, which is a kinase inhibitor drug used for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), FLT3-ITD positive AML and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino] phenoxy]-N-methyl-2-pyridinecarboxamide, 4-methylbenzenesulfonate (2:1). CAS No. 2056030-06-7. Molecular formula: C21H16ClF3N4O3.1/2(C7H8O3S). Mole weight: 550.92.
Sorafenib Hemi-Tosylate
Sorafenib Hemi-Tosylate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2056030-06-7. Molecular Formula: C21H16ClF3N4O3ยท 1/2 C7H8O3S. Mole Weight: 550.93. Catalog: APB2056030067.
Sorafenib Impurity 1
Sorafenib Impurity 1 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C28H25N7O6. Mole weight: 555.54.
Sorafenib Impurity 1
Sorafenib Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 99586-65-9. Molecular Formula: C6H5ClN2O. Mole Weight: 156.57. Catalog: APB99586659.
Sorafenib Impurity 10
Sorafenib Impurity 10 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: SORAFENIB IMPURITY 10; 2206827-14-5; propan-2-yl N-[4-[2-(methylcarbamoyl)pyridin-4-yl]oxyphenyl]carbamate; SORAFENIBIMPURITY10; EN300-6494528; Z3064469246; Isopropyl 4-[[2-(N-Methylcarbamoyl)-4-pyridyl]oxy]phenylcarbamate; propan-2-yl N-(4-{[2-(methylcarbamoyl)pyridin-4-yl]oxy}phenyl)carbamate. Molecular formula: C24H24F3N5O4. Mole weight: 503.47.
Sorafenib Impurity 10
Sorafenib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 284461-82-1. Molecular Formula: C22H18ClF3N4O3. Mole Weight: 478.86. Catalog: APB284461821.
Sorafenib Impurity 11
Sorafenib Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1290546-48-3. Molecular Formula: C21H16ClF3N4O3. Mole Weight: 464.83. Catalog: APB1290546483.
Sorafenib Impurity 11073
Sorafenib Impurity 11073. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2090542-70-2. Molecular Formula: C7H7FN2O3. Mole Weight: 186.14. Catalog: APB2090542702.
Sorafenib Impurity 13
Sorafenib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 583840-04-4. Molecular Formula: C20H14ClF3N4O4. Mole Weight: 466.8. Catalog: APB583840044.
Sorafenib Impurity 14
Sorafenib Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2206827-14-5. Molecular Formula: C17H19N3O4. Mole Weight: 329.36. Catalog: APB2206827145.
Sorafenib Impurity 15
Sorafenib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 871555-75-8. Molecular Formula: C14H9ClF3NO2. Mole Weight: 315.68. Catalog: APB871555758.
Sorafenib Impurity 16
Sorafenib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2206827-12-3. Molecular Formula: C16H17N3O4. Mole Weight: 315.33. Catalog: APB2206827123.
Sorafenib Impurity 17
Sorafenib Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53750-66-6. Molecular Formula: C6H3Cl2NO. Mole Weight: 176. Catalog: APB53750666.
Sorafenib Impurity 22
Sorafenib Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 777-37-7. Molecular Formula: C7H3ClF3NO2. Mole Weight: 225.55. Catalog: APB777377.
Sorafenib Impurity 24
Sorafenib Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 39974-35-1. Molecular Formula: C7H3ClF3NO2. Mole Weight: 225.55. Catalog: APB39974351.
Sorafenib Impurity 27
Sorafenib Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 583840-03-3. Molecular Formula: C21H16ClF3N4O4. Mole Weight: 480.83. Catalog: APB583840033.
Sorafenib Impurity 31
Sorafenib Impurity 31. Uses: For analytical and research use. Group: Impurity standards. CAS No. 62476-58-8. Molecular Formula: C7H5ClF3N. Mole Weight: 195.57. Catalog: APB62476588.
Sorafenib Impurity 4
Sorafenib Impurity 4 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C7H7NO2. Mole weight: 137.14.
Sorafenib Impurity 43
Sorafenib Impurity 43. Uses: For analytical and research use. Group: Impurity standards. CAS No. 757251-59-5. Molecular Formula: C13H12N2O3. Mole Weight: 244.25. Catalog: APB757251595.
Sorafenib Impurity 5
Sorafenib Impurity 5 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Molecular formula: C14H13ClN4O2. Mole weight: 304.73.
Sorafenib Impurity 5 (Regorafenib Impurity 5)
Sorafenib Impurity 5 (Regorafenib Impurity 5). Uses: For analytical and research use. Group: Impurity standards. CAS No. 320-51-4. Molecular Formula: C7H5ClF3N. Mole Weight: 195.57. Catalog: APB320514.
Sorafenib Impurity 6
Sorafenib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2204442-52-2. Molecular Formula: C27H23N5O6. Mole Weight: 513.51. Catalog: APB2204442522.
Sorafenib Impurity 7
Sorafenib Impurity 7 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4-Hydroxy-phenylhydroxylamine. Grades: ≥ 95%. CAS No. 3505-87-1. Molecular formula: C6H7NO2. Mole weight: 125.13.
Sorafenib Impurity 73
Sorafenib Impurity 73. Uses: For analytical and research use. Group: Impurity standards. CAS No. 862875-16-9. Molecular Formula: C21H17F3N4O4. Mole Weight: 446.39. Catalog: APB862875169.
Sorafenib Impurity 8
Sorafenib Impurity 8 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: Flucofuron; 370-50-3; Flucofuron [ISO]; TCMDC-137559; 1,3-bis[4-chloro-3-(trifluoromethyl)phenyl]urea; CHEBI:59242; 1,3-Bis(4-chloro-alpha,alpha,alpha-trifluoro-m-tolyl)urea; 1,3-bis(4-chloro-3-(trifluoromethyl)phenyl)urea; N,N'-bis[4-chloro-3-(trifluoromethyl)phenyl]urea; U3V3S70655; Mitin N; 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-chloro-3-(trifluoromethyl)phenyl)urea; N,N'-BIS(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREA. Molecular formula: C25H25F3N6O3. Mole weight: 514.50.
Sorafenib Impurity 84
Sorafenib Impurity 84. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1403469-80-6. Molecular Formula: C7H6Cl2N2O. Mole Weight: 205.04. Catalog: APB1403469806.
Sorafenib Impurity 85
Sorafenib Impurity 85. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1021077-12-2. Molecular Formula: C7H6Cl2N2O. Mole Weight: 205.04. Catalog: APB1021077122.
Sorafenib Impurity 86
Sorafenib Impurity 86. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1793080-72-4. Molecular Formula: C21H17F4N2O7P. Mole Weight: 516.34. Catalog: APB1793080724.
Sorafenib Impurity 87
Sorafenib Impurity 87. Uses: For analytical and research use. Group: Impurity standards. CAS No. 24484-93-3. Molecular Formula: C7H6ClNO2. Mole Weight: 171.58. Catalog: APB24484933.
Sorafenib Impurity 88
Sorafenib Impurity 88. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2004659-85-0. Molecular Formula: C13H12N2O2. Mole Weight: 228.25. Catalog: APB2004659850.
Sorafenib Impurity 9
Sorafenib Impurity 9 is one of Sorafenib impurities. Sorafenib is a polykinase inhibitor of Raf-1, B-Raf and VEGFR-2 and is an anti-tumor drug. Synonyms: 4- (4- (3- (4-Hydroxy-3- (trifluoromethyl) phenyl) ureido) phenoxy) -N-methylpicolinamide. CAS No. 862875-16-9. Molecular formula: C21H17F3N4O4. Mole weight: 446.38.
Sorafenib Impurity C
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Grades: > 95%. Molecular formula: C27H23N5O6. Mole weight: 513.51.
Sorafenib Impurity G
Sorafenib Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate. CAS No. 18585-06-3. Molecular Formula: C10H9ClF3NO2. Mole Weight: 267.63. Catalog: APB18585063.
Sorafenib Impurity I
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 1,3-bis-(4-Chloro-α,α,α-trifluoro-m-tolyl)urea. Grades: > 95%. CAS No. 370-50-3. Molecular formula: C15H8Cl2F6N2O. Mole weight: 417.13.
Sorafenib Impurity INT-1-B
Sorafenib Impurity INT-1-B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 220000-87-3. Molecular Formula: C7H7ClN2O. Mole Weight: 170.6. Catalog: APB220000873.
Sorafenib Impurity INT-1-F
Sorafenib Impurity INT-1-F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1065074-98-7. Molecular Formula: C8H11N3O. Mole Weight: 165.2. Catalog: APB1065074987.
Sorafenib Impurity INT-1-N
Sorafenib Impurity INT-1-N. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1863331-80-9. Molecular Formula: C9H13N3O. Mole Weight: 179.22. Catalog: APB1863331809.
Sorafenib Impurity INT-1-O
Sorafenib Impurity INT-1-O. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C9H14N4O. Mole Weight: 194.24. Catalog: APB09538.
Sorafenib Impurity INT-2-G
Sorafenib Impurity INT-2-G. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H21N5O4. Mole Weight: 455.47. Catalog: APB09539.
Sorafenib Impurity INT-2-L
Sorafenib Impurity INT-2-L. Uses: For analytical and research use. Group: Impurity standards. CAS No. 864272-34-3. Molecular Formula: C13H11N3O4. Mole Weight: 273.25. Catalog: APB864272343.
Sorafenib Impurity INT-2-M
Sorafenib Impurity INT-2-M. Uses: For analytical and research use. Group: Impurity standards. CAS No. 284462-80-2. Molecular Formula: C12H11N3O2. Mole Weight: 229.24. Catalog: APB284462802.
Sorafenib Impurity INT-2-N
Sorafenib Impurity INT-2-N. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H11N3O4. Mole Weight: 273.25. Catalog: APB09540.
Sorafenib Impurity U
Sorafenib Impurity U. Uses: For analytical and research use. Group: Impurity standards. CAS No. 5470-22-4. Molecular Formula: C6H4ClNO2. Mole Weight: 157.55. Catalog: APB5470224.
Sorafenib-methyl-d3
Labeled Sorafenib, a potent Raf kinase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Sorafenib N-oxide
Sorafenib N-oxide. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] phenoxy] -N-methyl-2-pyridinecarboxamide 1-oxide. Grades: Highly Purified. CAS No. 583840-03-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H16ClF3N4O4. US Biological Life Sciences.
Worldwide
Sorafenib-N-oxide
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Uses: Protein kinase inhibitors. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide 1-oxide. Grades: > 95%. CAS No. 583840-03-3. Molecular formula: C21H16ClF3N4O4. Mole weight: 480.82.
Sorafenib, p-Toluenesulfonate Salt
Sorafenib (Bay 43-9006) is a novel bi-aryl urea compound that inhibits cell proliferation by targeting the ERK pathway and angiogenesis by targeting the receptor tyrosine kinases VEGFR-2 and PDGFR-b and their associated signaling cascades. Although sorafenib was initially developed as a Raf kinase inhibitor (IC50=6nM), it has since been shown to have activity against many receptor tyrosine kinases involved in tumorigenesis and angiogenesis including FGFR-1, wt BRAF and V599E mutant BRAF, as well as members of the so-called "split kinase" family: VEGFR-2, VEGFR-3, PDGFR-b, c-KIT, and Flt3. However, sorafenib is not active against erbB1, erbB2, ERK-1, MEK-1, EGFR, HER-2, IGFR-1, c-MET, c-yes, PKB, PKA, cdk1/cyclinB, PKC, and pim-1. In cellular mechanistic assays, sorafenib decreased basal phosphorylation of the ERK pathway in melanoma, breast, colon, and pancreatic tumor cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 475207-59-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C21H16ClF3N4O3 C7H8O3S, Molecular Weight: 637.03. US Biological Life Sciences.
Worldwide
Sorafenib Related Compound
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-methyl-4-phenoxy-2-Pyridinecarboxamide. Grades: > 95%. CAS No. 2004659-85-0. Molecular formula: C13H12N2O2. Mole weight: 228.25.
Sorafenib related compound 1
Sorafenib related compound 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2208275-83-4. Molecular Formula: C8H6ClF3N2O. Mole Weight: 238.59. Catalog: APB2208275834.
Sorafenib related compound 10
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxylic Acid; 4- (4- (3- (4-Chloro-3- (trifluoromethyl) phenyl) ureido) phenoxy) picolinic Acid; Sorafenib Hydroxydemethylamine. Grades: > 95%. CAS No. 1012058-78-4. Molecular formula: C20H13ClF3N3O4. Mole weight: 451.79.
Sorafenib related compound 10
Sorafenib related compound 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1012058-78-4. Molecular Formula: C20H13ClF3N3O4. Mole Weight: 451.79. Catalog: APB1012058784.
Sorafenib related compound 11
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-Methyl-4-[4-[[2-[(methylamino)carbonyl]-4-pyridinyl]amino]phenoxy]-2-pyridinecarboxamide. Grades: > 95%. CAS No. 2004659-83-8. Molecular formula: C20H19N5O3. Mole weight: 377.40.
Sorafenib related compound 11
Sorafenib related compound 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2004659-83-8. Molecular Formula: C20H19N5O3. Mole Weight: 377.4. Catalog: APB2004659838.
Sorafenib related compound 12
Sorafenib related compound 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2004659-84-9. Molecular Formula: C14H13N3O3. Mole Weight: 271.28. Catalog: APB2004659849.
Sorafenib Related Compound 12
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-(formylamino)phenoxy]-N-methyl-2-Pyridinecarboxamide. Grades: > 95%. CAS No. 2004659-84-9. Molecular formula: C14H13N3O3. Mole weight: 271.27.
Sorafenib related compound 13
Sorafenib related compound 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 845306-04-9. Molecular Formula: C7H7ClN2O. Mole Weight: 170.6. Catalog: APB845306049.
Sorafenib Related Compound 13
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 6-Chloro-N-methylpicolinamide; 6-Chloro-N-methyl-2-pyridinecarboxamide. Grades: > 95%. CAS No. 845306-04-9. Molecular formula: C7H7ClN2O. Mole weight: 170.6.
Sorafenib related compound 14
Sorafenib related compound 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 284461-74-1. Molecular Formula: C20H14ClF3N4O3. Mole Weight: 450.8. Catalog: APB284461741.
Sorafenib Related Compound 14
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]phenoxy]-2-pyridinecarboxamide; BAY 43-9007; N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-(2-carbamoyl-4-pyridyloxy)phenyl]urea; N-Desmethyl Sorafenib. Grades: > 95%. CAS No. 284461-74-1. Molecular formula: C20H14ClF3N4O3. Mole weight: 450.81.
Sorafenib related compound 15
Sorafenib related compound 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 284670-98-0. Molecular Formula: C27H24N6O5. Mole Weight: 512.53. Catalog: APB284670980.
Sorafenib Related Compound 15
An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: 4,4'-[Carbonylbis(imino-4,1-phenyleneoxy)]bis[N-methyl-2-pyridinecarboxamide]; PAPE-urea; N,N'-Bis[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea. Grades: > 95%. CAS No. 284670-98-0. Molecular formula: C27H24N6O5. Mole weight: 512.53.
Sorafenib related compound 16
Sorafenib related compound 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1256817-30-7. Molecular Formula: C8H10N2O2. Mole Weight: 166.18. Catalog: APB1256817307.
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