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Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d4T. CAS No. 3056-17-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0116.
Stavudine
Used as an antiviral. A reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-3'-deoxythymidine, D4t, BMY-27857, Zerit. Grades: Highly Purified. CAS No. 3056-17-5. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C10H12N2O4, Molecular Weight: 224.21. US Biological Life Sciences.
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Stavudine 5'-monophosphate sodium salt
Stavudine 5'-monophosphate sodium salt. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-2',3'-dideoxythymidine-5'-monophosphate sodium salt. Grades: Highly Purified. Pack Sizes: 50ug, 250ug, 500ug. US Biological Life Sciences.
Worldwide
Stavudine 5'-monophosphate sodium salt
Stavudine 5'-monophosphate sodium salt is an indispensable pharmaceutical compound in the research of HIV/AIDS, acting as a nucleoside reverse transcriptase inhibitor. Through intricate interference with the genetic material of the virus, it effectively obstructs viral replication. Synonyms: 2',3'-Didehydro-2',3'-dideoxythymidine-5'-monophosphate sodium salt. Molecular formula: C10H13N2O7P·xNa. Mole weight: 304.19 (free acid).
Stavudine 5'-monophosphate triethyammonium salt
Stavudine 5'-monophosphate triethyammonium salt. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-2'-3'-dideoxythymidine 5'-monophosphate sodium salt. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Stavudine 5'-monophosphate triethyammonium salt
Stavudine 5'-monophosphate triethyammonium salt is an invaluable biomedical compound, serving as a potent tool for studying HIV infection. By effectively impeding the virus's replication, it functions as an exemplary nucleotide reverse transcriptase inhibitor. Such inhibition is augmented by the salt form is as it heightens the stability and solubility of stavudine 5'-monophosphate. Synonyms: 2',3'-Didehydro-2'-3'-dideoxythymidine 5'-monophosphate sodium salt.
Stavudine 5-O-β-Glucuronide
Stavudine 5-O-β-Glucuronide is the O-glucuronide derivative of Stavudine; a reverse transcriptase inhibitor and antiviral. Synonyms: 2',3'-Didehydro-3'-deoxythymidine 5-O-β-Glucuronide; 3'-Deoxy-2'-thymidinene 5-O-β-Glucuronide; 3'-Deoxy-2',3'-didehydrothymidine 5-O-β-Glucuronide; Avostav 5-O-β-Glucuronide; D4t 5-O-β-Glucuronide; BMY-27857 5-O-β-Glucuronide; Zerit 5-O-β-Glucuronide; NSC 163661 5-O-β-Glucuronide; Sanilvudine 5-O-β-Glucuronide; Virostav 5-O-β-Glucuronide; 1-[(2R,5S)-2,5-Dihydro-5-(hydroxymethyl)-2-furanyl]-5-methyl-2,4(1H,3H)-pyrimidinedione 5-O-β-Glucuronide; 1-(2,3-Dideoxy-β-D-glycero-pent-2-enofuranosyl)thymine 5-O-β-Glucuronide; (2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-(((2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methoxy)tetrahydro-2H-pyran-2-carboxylic Acid. Molecular formula: C16H20N2O10. Mole weight: 400.34.
Stavudine 5'-triphosphate sodium salt
Stavudine 5'-triphosphate sodium salt. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-2',3'-dideoxy-thymidine-5'-triphosphate sodium salt. Grades: Highly Purified. Pack Sizes: 100ug, 200ug. US Biological Life Sciences.
Worldwide
Stavudine 5'-triphosphate sodium salt
Stavudine 5'-triphosphate sodium salt is a paramount constituent within the biomedical sector, aiding in studying viral infections instigated by the human immunodeficiency virus (HIV). Serving as an antiretroviral compound, it effectively hampers the HIV reverse transcriptase enzyme and thwarts viral reproduction. Synonyms: 2',3'-Didehydro-2',3'-dideoxy-thymidine-5'-triphosphate sodium salt. Molecular formula: C10H15N2O13P3·xNa. Mole weight: 464.15 (free acid).
Stavudine 5'-triphosphate triethyammonium salt
Stavudine 5'-triphosphate triethyammonium salt. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-2'-3'-dideoxythymidine 5'-triphosphate sodium salt. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Stavudine 5'-triphosphate triethyammonium salt
Stavudine 5'-triphosphate triethyammonium salt is a vital bioactive constituent adopted within the research of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). By virtue of its potent action in disabling the reverse transcriptase enzyme associated with HIV, this invaluable compound imparts a noteworthy hampering effect on the viral replication process. Synonyms: 2',3'-Didehydro-2'-3'-dideoxythymidine 5'-triphosphate sodium salt.
Labeled Stavudine, which is used as an antiviral. A reverse transcriptase inhibitor. Group: Biochemicals. Alternative Names: 2',3'-Didehydro-3'-deoxythymidine-d3. Grades: Highly Purified. CAS No. 1217619-42-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Stavudine sodium
Stavudine sodium is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine sodium is an analog of thymidine. It is phosphorylated by cellular kinases into active triphosphate. Stavudine sodium triphosphate inhibits the HIV reverse transcriptase by competing with natural substrate, thymidine triphosphate. It also causes termination of DNA synthesis by incorporating into it. Mice were treated for 2 weeks with stavudine d4T (500 mg/kg/day), L-carnitine (200 mg/kg/day) or both drugs concomitantly. Body fatness was assessed by dual energy X-ray absorptiometry, and investigations were performed in plasma, liver, muscle and WAT. D4T reduced the gain of body adiposity, WAT leptin, whole body FAO and plasma ketone bodies, and increased liver triglycerides and plasma aminotransferases with mild ultrastructural abnormalities in hepatocytes. Synonyms: Zerit sodium; d4T sodium. Grades: >98%. CAS No. 134624-73-0. Molecular formula: C10H11N2NaO4. Mole weight: 246.2.
Stavudine (Standard)
Stavudine (Standard) is the analytical standard of Stavudine. This product is intended for research and analytical applications. Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3056-17-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0116R.
Stavudine Triphosphate TEA Salt
Stavudine Triphosphate TEA Salt. Group: Biochemicals. Alternative Names: 5'-(Tetrahydrogen triphosphate), 2',3'-didehydro-3'-deoxy-thymidine N,N-Diethylethanamine Triethylamine Salt. Grades: Highly Purified. CAS No. 117404-75-8. Pack Sizes: 5mg. Molecular Formula: C16H30N3O13P3, Molecular Weight: 565.34. US Biological Life Sciences.
Worldwide
Stavudine Triphosphate Trisodium Salt
Stavudine Triphosphate Trisodium Salt. Group: Biochemicals. Alternative Names: 22',3'-Didehydro-3'-deoxythymidine-5'-triphosphate Trisodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H12N2Na3O13P3, Molecular Weight: 530.1. US Biological Life Sciences.
Worldwide
Benzoyl stavudine
Benzoyl stavudine. Group: Biochemicals. Alternative Names: 5'-Benzoyl-3'-deoxy-2',3'-didehydrothymidine. Grades: Highly Purified. CAS No. 122567-97-9. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C17H16N2O5. US Biological Life Sciences.
Worldwide
1,2,5-Tri-O-acetyl-3-deoxy-D-ribofuranose
1,2,5-Tri-O-acetyl-3-deoxy-D-ribofuranose, a vital biochemical compound, stands as the gateway to the manufacture of an assortment of pharmaceuticals. Known for its efficacy in antiviral drug preparation namely stavudine and zalcitabine, its use extends to the synthesis of antibiotics catering for bacterial infections in antibiotics such as anthracyclines. The purity and easy accessibility of this ingredient, woven into the fabric of the pharmaceutical industry, make it an optimal choice. CAS No. 865853-43-6. Molecular formula: C11H16O7. Mole weight: 260.24.
1,2-O-Isopropylidene-3-deoxy-a-D-allofuranose
1,2-O-Isopropylidene-3-deoxy-a-D-allofuranose, a critical component in the production of significant medicines such as stavudine and didanosine, is an essential intermediate in their synthesis. Besides, it finds application in formulating biological tracers for exploring the activity of glycosylation-related enzymes and processes. Its versatile roles in pharmacology and biochemistry research make it an indispensable compound. Synonyms: (R)-1-((3AR,5S,6AR)-2,2-DIMETHYLTETRAHYDROFURO[2,3-D][1,3]DIOXOL-5-YL)ETHANE-1,2-DIOL; (1R)-1-[(3aR,5S,6aR)-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol; MFCD27950881; SCHEMBL347878; 1-O,2-O-Isopropylidene-3-deoxy-alpha-D-allofuranose; CWSMTGSMKMNOOX-ULAWRXDQSA-N; BS-41764; CS-0036262; W11976; 3-Deoxy-1,2-O-(1-methylethylidene)-a-D-ribo-hexofuranose; (1R)-1-[(3aR,5S,6aR)-2,2-dimethyl-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol. CAS No. 4494-96-6. Molecular formula: C9H16O5. Mole weight: 204.22.
1,3,5-Tri-O-acetyl-2-deoxy-b-D-ribofuranose
1,3,5-Tri-O-acetyl-2-deoxy-b-D-ribofuranose is a vital precursor in the synthesis of antiviral drugs such as Zalcitabine and Stavudine. It is also valuable in cancer research, aiding in DNA therapeutic development. CAS No. 96291-75-7. Molecular formula: C11H16O7. Mole weight: 260.24.
3'-β-Thymidine
As an intermediate in the production of fluorothymidine and phosphorylase derivatives 3'-β-Thymidine (Stavudine EP Impurity B) is used as an antiviral agent. Reverse transcriptase inhibitor. Synonyms: 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyluricil; 1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-thymine; NSC 526738; Stavudine EP Impurity B; 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 16053-52-4. Molecular formula: C10H14N2O5. Mole weight: 242.23.
Censavudine is a nucleoside reverse transcriptase inhibitor. It is active against HIV resistant to both abacavir and tenofovir. It is a candidate for people with multi-drug resistant (MDR) strains of the virus. It is a derivative of stavudine (d4T), but is less toxic. It has demonstrated potent in vitro activity against HIV-2. It was developed by Bristol Myers-Squibb and in clinic phase 2 trials. Uses: Censavudine is active against hiv resistant to both abacavir and tenofovir. Synonyms: OBP-601; OBP601; OBP 601; BMS-986001; BMS 986001; BMS986001; festinavir; 4'-Ed4T; Censavudine; 2',3'-Didehydro-3'-deoxy-4'-ethynylthymidine;4'-Ed4T;4'-Ethynylstavudine;4'-Ethynyl D4T;1-[(2R,5R)-5-ethynyl-5-(hydroxymethyl)-2H-furan-2-yl]-5-methylpyrimidine-2,4-dione. Grades: 98%. CAS No. 634907-30-5. Molecular formula: C12H12N2O4. Mole weight: 248.24.
d4TMP
d4TMP, a potent nucleoside analog, is a promising therapeutic agent against various cancers, notably lymphoma and leukemia. Its unique mechanism of action disrupts DNA synthesis, culminating in cancer cell death. Intriguingly, researchers are now exploring the potential of d4TMP in diverse viral afflictions, including HIV and hepatitis B. Synonyms: Stavudine monophosphate, Sodium Salt; 2',3'-Didehydro-2',3'-dideoxythymidine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 3715-64-8. Molecular formula: C10H13N2O7P (free acid). Mole weight: 304.19 (free acid).
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