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FK-506 is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Uses: Drug. Synonyms: Prograf; Fujimycin; FK506; Protopy. Grades: >98%. CAS No. 104987-11-3. Molecular formula: C44H69NO12. Mole weight: 804.02.
Tacrolimus
Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: FK506; Fujimycin; FR900506. CAS No. 104987-11-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13756.
Tacrolimus 15 DMT is a metabolite of Tacrolimus, an immunosuppressant that inhibits the activity of FK-506-binding protein. Synonyms: 15-O-Desmethyl Tacrolimus; 13-O-Demethyl-FK-506; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 14, 19-trihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-16-methoxy-4, 10, 12, 18-tetramethyl-8-(2-propen-1-yl)-, (3S, 4R, 5S, 8R, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-. Grades: >98%. CAS No. 151039-41-7. Molecular formula: C43H67NO12. Mole weight: 789.99.
Tacrolimus 15-DMT
Tacrolimus-19-Desmethyl Impurity
Tacrolimus-19-Desmethyl is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Molecular formula: C43H67NO12. Mole weight: 789.99.
Tacrolimus 21-Carboxy Acid
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: 21-Carboxy Acid Tacrolimus. Grades: > 95%. Molecular formula: C44H71NO13. Mole weight: 822.06.
Tacrolimus 31 DMT
Tacrolimus 31 DMT is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: O-desmethyl Tacrolimus; Hydroxy Tacrolimus; (18E)-17-Allyl-12-[(1E)-1-(3,4-dihydroxycyclohexyl)-1-propen-2-yl]-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone. Grades: >98%. CAS No. 135635-47-1. Molecular formula: C43H67NO12. Mole weight: 789.99.
Tacrolimus 31-DMT
Tacrolimus 31-DMT is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: 12-[1-(3,4-Dihydroxycyclohexyl)prop-1-en-2-yl]-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone; Tacrolimus 31 DMT; VHOPGJHKSPGXIZ-UHFFFAOYSA-N; 17-Allyl-1,14-dihydroxy-12-[2-(3,4-dihydroxycyclohexyl)-1-methylvinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene-2,3,10,16-tetraone. CAS No. 127984-76-3. Molecular formula: C43H67NO12. Mole weight: 789.99.
Tacrolimus alpha-Hydroxy Acid
Tacrolimus alpha-Hydroxy Acid (TAC-H1) is an impuritie of Tacrolimus,which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: TAC-H1. Molecular formula: C45H73NO13. Mole weight: 836.06.
Tacrolimus C4-epimer Diene
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus C4-epimer Diene. Grades: > 95%. Molecular formula: C44H67NO11. Mole weight: 786.02.
Tacrolimus EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Ethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. CAS No. 104987-12-4. Molecular Formula: C43H69NO12. Mole Weight: 792.01. Catalog: APB104987124.
Tacrolimus EP Impurity C
Tacrolimus EP Impurity C is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 12, 18-trimethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; 10-Desmethyl tacrolimus; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 12, 18-trimethyl-8-(2-propen-1-yl)-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; Tacrolimus monohydrate EP impurity C; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Allyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl]-14, 16-dimethoxy-4, 12, 18-trimethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone; Desmethyl tacrolimus. Grades: ≥95%. Molecular formula: C43H67NO12. Mole weight: 789.99.
Tacrolimus EP Impurity D
Tacrolimus EP Impurity D is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; 8-epi Tacrolimus; 8-Epitacrolimus; Tacrolimus anhydrous 8-epimer; Tacrolimus 8-epimer [USP-RS]; Tacrolimus monohydrate impurity D [EP]; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8R*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-; (-)-8-epi-Tacrolimus; (3S, 4R, 5S, 8S, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-8-Allyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-{(E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: ≥90% by HPLC. CAS No. 129212-35-7. Molecular formula: C44H69NO12. Mole weight: 804.04.
Tacrolimus EP Impurity D
Tacrolimus EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 8-epi Tacrolimus; (3S, 4R, 5S, 8S, 12S, 14S, 15R, 16S, 18R, 19R, 26aS, E)-8-allyl-5, 19-dihydroxy-3-((E)-1-((1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-3H-15, 19-epoxypyrido[2, 1-c][1]oxa[4]azacyclotricosine-1, 7, 20, 21(4H, 23H)-tetraone. CAS No. 129212-35-7. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB129212357.
Tacrolimus EP Impurity E
Tacrolimus EP Impurity E is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; Dihydro Tacrolimus; Dihydro-FK 506; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-. Grades: ≥90% by HPLC. CAS No. 104987-30-6. Molecular formula: C44H71NO12. Mole weight: 806.06.
Tacrolimus EP Impurity E
Tacrolimus EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-5, 19-dihydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-propyl-3, 4, 5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-octadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone. CAS No. 104987-30-6. Molecular Formula: C44H71NO12. Mole Weight: 806.03. Catalog: APB104987306.
Tacrolimus EP Impurity F
Tacrolimus EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (3S, 4R, 5S, 8R, 12S, 14S, 15R, 16S, 18R, 26aS, E)-8-allyl-5, 15-dihydroxy-3-((E)-1-((1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-3, 4, 5, 6, 11, 12, 13, 14, 15, 16, 17, 18, 24, 25, 26, 26a-hexadecahydro-1H-pyrido[2, 1-c][1, 4]oxaaz. CAS No. 1393890-33-9. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB1393890339.
Tacrolimus EP Impurity G
Cas No. 144490-63-1.
Tacrolimus EP Impurity G
Tacrolimus EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Tacrolimus 19-epimer. CAS No. 144490-63-1. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB144490631.
Tacrolimus EP Impurity H
Tacrolimus EP Impurity H is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (1E,3S,4R,5S,8R,9E,12S,14S)-5-hydroxy-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-14-methoxy-14-[(2R,3S,5R)-3-methoxy-5-methyl-6-oxooxan-2-yl]-2,4,10,12-tetramethyl-7-oxo-8-(prop-2-en-1-yl)tetradeca-1,9-dien-3-yl (2S)-1-formylpiperidine-2-carboxylate; Tacrolimus monohydrate impurity H [EP]; 2-Piperidinecarboxylic acid, 1-formyl-, (1S,2R,3S,6R,7E,10S,12S)-3-hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-12-methoxy-2,8,10-trimethyl-5-oxo-6-(2-propen-1-yl)-12-[(2R,3S,5R)-tetrahydro-3-methoxy-5-methyl-6-oxo-2H-pyran-2-yl]-7-dodecen-1-yl ester, (2S)-; (1S,2R,3S,6R,7E,10S,12S)-3-Hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-12-methoxy-2,8,10-trimethyl-5-oxo-6-(2-propen-1-yl)-12-[(2R,3S,5R)-tetrahydro-3-methoxy-5-methyl-6-oxo-2H-pyran-2-yl]-7-dodecen-1-yl (2S)-1-formyl-2-piperidinecarboxylate; 2-Piperidinecarboxylic acid, 1-formyl-, (1S,2R,3S,6R,7E,10S,12S)-3-hydroxy-1-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-12-methoxy-2,8,10-trim. Grades: ≥95%. CAS No. 143210-33-7. Molecular formula: C43H69NO11. Mole weight: 776.01.
Tacrolimus EP Impurity I
Tacrolimus EP Impurity I is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (3S, 4R, 5E, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-19-hydroxy-3-[(1E)-1-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(prop-2-en-1-yl)-3, 4, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-hexadecahydro-7H-15, 19-epoxypyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(23H)-tetrone; Tacrolimus diene; 23,24-Anhydro Tacrolimus; Δ23-FK-506; Tacrolimus Impurity I; Tacrolimus monohydrate impurity I [EP]; 15,19-Epoxy(5E,9E)-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-tetradecahydro-19-hydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propen-1-yl)-, (3S, 4R, 8R, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-; 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-tetradecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-, [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5E, 8S*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-. Grades: ≥90% by HPLC. CAS No. 104987-16-8. Molecular formula: C44H67NO11. Mole weight: 786.02.
Tacrolimus Impurity 1
Tacrolimus Impurity 1 is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: Tacrolimus Impurity 1. Grades: ≥95%. Molecular formula: C43H69NO11. Mole weight: 776.03.
Tacrolimus Impurity 11
Tacrolimus Impurity 11 is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Molecular formula: C44H73NO13. Mole weight: 824.05.
Tacrolimus Impurity 12
Tacrolimus Impurity 12 is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Synonyms: (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 19R, 26aS)-15, 19-Epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-19-dehydroxy-20, 21, 22-oxazolidinone-1, 7, 20, 21(4H, 23H)-tetrone. Molecular formula: C44H69NO12. Mole weight: 804.02.
Tacrolimus Impurity 13
Tacrolimus Impurity 13 is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. Molecular formula: C44H69NO12. Mole weight: 804.02.
Tacrolimus Impurity 13
Tacrolimus Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1026775-21-2. Molecular Formula: C44H69NO12. Mole Weight: 804.03. Catalog: APB1026775212.
Tacrolimus Impurity 14
Tacrolimus Impurity 14 is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. CAS No. 1260758-24-4. Molecular formula: C10H15NO4S. Mole weight: 245.29.
Tacrolimus Impurity 14
Tacrolimus Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1260758-24-4. Molecular Formula: C10H15NO4S. Mole Weight: 245.29. Catalog: APB1260758244.
Tacrolimus Impurity 16
Tacrolimus Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 135821-70-4. Molecular Formula: C44H67NO11. Mole Weight: 786.02. Catalog: APB135821704.
Tacrolimus Impurity 18
Tacrolimus Impurity 18 is an impuritie of Tacrolimus, which is a macrolide drug that is widely used as a potent immunosuppressant. CAS No. 129039-81-2. Molecular formula: C43H65NO12. Mole weight: 787.97.
Tacrolimus Impurity 18
Tacrolimus Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 129039-81-2. Molecular Formula: C43H65NO12. Mole Weight: 787.99. Catalog: APB129039812.
Tacrolimus Impurity 2
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacroliums Impurity D; [3R-[3R*(1R*, 3R*, 4R*), 4E, 6S*, 7S*, 10R*, 11E, 14S*, 16S*, 17R*, 18S*, 20R*, 21R*, 28aS*]]-7, 8, 10, 13, 14, 15, 16, 17, 18, 19, 20, 21, 26, 27, 28, 28a-Hexadecahydro-7, 21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16, 18-dimethoxy-4, 6, 12, 14, 20-pentamethyl-10-(2-propenyl)-7, 21-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclopentacosine-1, 9, 22, 23(6H, 25H)-tetrone. Grades: > 95%. CAS No. 131944-48-4. Molecular formula: C44H69NO12. Mole weight: 804.04.
Tacrolimus Impurity 20
Tacrolimus Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 127984-76-3. Molecular Formula: C43H67NO12. Mole Weight: 790. Catalog: APB127984763.
Tacrolimus Impurity 22
Tacrolimus Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1700657-83-5. Molecular Formula: C44H71NO13. Mole Weight: 822.05. Catalog: APB1700657835.
Tacrolimus Impurity 23
Tacrolimus Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 133941-75-0. Molecular Formula: C56H97NO12Si2. Mole Weight: 1032.56. Catalog: APB133941750.
Tacrolimus Impurity 24
Tacrolimus Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1356352-20-9. Molecular Formula: C5513CH95D2NO12Si2. Mole Weight: 1035.56. Catalog: APB1356352209.
Tacrolimus Impurity 25
Tacrolimus Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1356932-17-6. Molecular Formula: C56H99NO14Si2. Mole Weight: 1066.57. Catalog: APB1356932176.
Tacrolimus Impurity 26
Tacrolimus Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 104987-25-9. Molecular Formula: C50H83NO12Si. Mole Weight: 918.29. Catalog: APB104987259.
Tacrolimus Impurity 29
Tacrolimus Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 131944-48-4. Molecular Formula: C44H69NO12. Mole Weight: 804.02. Catalog: APB131944484.
Tacrolimus Impurity 3
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Impurity 3. Grades: > 95%. Molecular formula: C43H69NO11. Mole weight: 776.03.
Tacrolimus Impurity 37
Tacrolimus Impurity 37. Uses: For analytical and research use. Group: Impurity standards. CAS No. 135635-47-1. Molecular Formula: C43H67NO12. Mole Weight: 789.99. Catalog: APB135635471.
Tacrolimus Impurity 38
Tacrolimus Impurity 38. Uses: For analytical and research use. Group: Impurity standards. CAS No. 143210-33-7. Molecular Formula: C43H69NO11. Mole Weight: 776.02. Catalog: APB143210337.
Tacrolimus Impurity 39
Tacrolimus Impurity 39. Uses: For analytical and research use. Group: Impurity standards. CAS No. 109581-93-3. Molecular Formula: C44H71NO13. Mole Weight: 822.05. Catalog: APB109581933.
Tacrolimus Impurity 4
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Impurity 4. Grades: > 95%. Molecular formula: C44H69NO12. Mole weight: 804.04.
Tacrolimus Impurity 5
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Impurity 5. Grades: > 95%. Molecular formula: C44H71NO13. Mole weight: 822.06.
Tacrolimus Impurity 53
Tacrolimus Impurity 53. Uses: For analytical and research use. Group: Impurity standards. CAS No. 123719-19-7. Molecular Formula: C43H69NO11. Mole Weight: 776.02. Catalog: APB123719197.
Tacrolimus Impurity 54
Tacrolimus Impurity 54. Uses: For analytical and research use. Group: Impurity standards. CAS No. 139958-51-3. Molecular Formula: C43H67NO12. Mole Weight: 790. Catalog: APB139958513.
Tacrolimus Impurity 6
Tacrolimus Impurity 6 is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: Pyrido[2,1-c][1,4]oxaazacyclodocosine-19-carboxylic acid, 1, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 22, 23, 24, 25, 25a-docosahydro-5, 15, 19-trihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-1, 7, 20-trioxo-8-(2-propen-1-yl)-, (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 25aS)-; (3S, 4R, 5S, 8R, 9E, 12S, 14S, 15R, 16S, 18R, 25aS)-1, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 22, 23, 24, 25, 25a-Docosahydro-5, 15, 19-trihydroxy-3-[(1E)-2-[(1R, 3R, 4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-1, 7, 20-trioxo-8-(2-propen-1-yl)pyrido[2, 1-c][1, 4]oxaazacyclodocosine-19-carboxylic acid; Tacrolimus α-hydroxy acid; Tacrolimus hydroxy acid. Grades: >95%. CAS No. 1700657-83-5. Molecular formula: C44H71NO13. Mole weight: 822.06.
Tacrolimus Impurity 7
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Impurity 7. Grades: > 95%. Molecular formula: C44H69NO12. Mole weight: 804.04.
Tacrolimus Impurity 7
Tacrolimus Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 124554-37-6. Molecular Formula: C44H69NO13. Mole Weight: 820.03. Catalog: APB124554376.
Tacrolimus Impurity 8
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Impurity 8. Grades: > 95%. Molecular formula: C44H71NO13. Mole weight: 822.06.
Tacrolimus Impurity 9
Tacrolimus Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144432-23-5. Molecular Formula: C44H71NO13. Mole Weight: 822.05. Catalog: APB144432235.
Tacrolimus Impurity (Methyl Acryl Aldehyde)
Tacrolimus Impurity (Methyl Acryl Aldehyde) is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (E)-3-[[(1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl]-2-methylacrylaldehyde; [1R-[1α(E),3α,4β]]-3-(4-Hydroxy-3-methoxycyclohexyl)-2-methyl-2-propenal; Tacrolimus Methylacryl Aldehyde; 3-((1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl)-2-methylacrylaldehyde, (E)-; (2E)-3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methylprop-2-enal; (2E)-3-[(1R,3R,4R)-4-Hydroxy-3-methoxycyclohexyl]-2-methylacrylaldehyde; 2-Propenal, 3-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-methyl-, (2E)-. Grades: ≥90% by HPLC. CAS No. 109466-74-2. Molecular formula: C11H18O3. Mole weight: 198.26.
Tacrolimus Lactone Isomer
One of the isomer impurities of Tacrolimus Lactone, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Iso-FK-506 (iso-Tacrolimus); [3S-[3R*[1R*, 2R*, 4(1S*, 3S*, 4S*)], 6S*, 10R*, 12R*, 13R*, 14R*, 16S*, 17S*, 24aR*]]-6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 24, 24a-tetradecahydro-17-hydroxy-3-[2-hydroxy-4-(4-hydroxy-3-methoxycyclohexyl)-1, 3-dimethyl-3-butenyl]-12, 14-dimethoxy-8, 10, 16-trimethyl-6-(2-propenyl)-13, 17-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacycloheneicosine-1, 5, 18, 19(4H, 21H)-tetrone. Grades: >95%. CAS No. 134590-88-8. Molecular formula: C44H69NO12. Mole weight: 804.02.
Tacrolimus Lactone Isomer
Tacrolimus Lactone Isomer. Uses: For analytical and research use. Group: Impurity standards. CAS No. 134590-88-8. Molecular Formula: C44H69NO12. Mole Weight: 804.03. Catalog: APB134590888.
Tacrolimus Methylacryl Aldehyde
Tacrolimus Methyl Acryl Aldehyde is the degradation product of Tacrolimus, a novel macrocyclic lactone isolated from Streptomyces tsukubaensis, having immunosuppressant activity. Group: Biochemicals. Alternative Names: [1R-[1α(E), 3α, 4 β]]-3-(4-Hydroxy-3-methoxycyclohexyl)-2-methyl-2-propenal. Grades: Highly Purified. CAS No. 109466-74-2. Pack Sizes: 10mg. Molecular Formula: C??H??O?, Molecular Weight: 198.26. US Biological Life Sciences.
Worldwide
Tacrolimus monohydrate
Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase , which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: FK506 monohydrate; Fujimycin monohydrate; FR900506 monohydrate. CAS No. 109581-93-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13756A.
Tacrolimus monohydrate
Tacrolimus monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 109581-93-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C44H69NO12·H2O. US Biological Life Sciences.
Worldwide
Tacrolimus regioisomer
Tacrolimus regioisomer is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: (4E, 11E)-10-Allyl-7, 8, 10, 13, 14, 15, 16, 17, 18, 19, 20, 21, 26, 22, 28, 28a-hexadecahydro-7, 21-dihydroxy-3-(4-hydroxy-3-methoxycyclohexyl)-16, 18-dimethoxy-4, 6, 12, 14, 20-pentamethyl-17, 21-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclopentacosine-1, 9, 22, 23(6H, 25H)-tetrone. Molecular formula: C44H69NO12. Mole weight: 804.03.
Tacrolimus Ring-opening Impurity
One of the impurities of Tacrolimus, which is a kind of immunosuppressant and could restrain the activity of FK-506 binding protein. Synonyms: Tacrolimus Ring-opening Impurity. Grades: > 95%. Molecular formula: C44H69NO12. Mole weight: 804.04.
Tacrolimus USP Related Compound A is an impurity of Tacrolimus, which is a calcineurin inhibitor used as an immunosuppressant after organ transplantation to reduce the activity of the patient's immune system, thereby reducing the risk of organ rejection. Synonyms: USP Tacrolimus Related Compound A; (E)-8-Ethyl-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21-(4H, 23H)-tetrone. Grades: ≥95%. Molecular formula: C43H69NO12. Mole weight: 792.01.
Tacrolimus USP Related Compound A (Tacrolimus Impurity 49)
Tacrolimus USP Related Compound A (Tacrolimus Impurity 49). Uses: For analytical and research use. Group: Impurity standards. CAS No. 135635-46-0. Molecular Formula: C43H69NO12. Mole Weight: 792.01. Catalog: APB135635460.
19-epi Tacrolimus
19-epi Tacrolimus is an impurity of Tacrolimus. Tacrolimus is an immunosuppressant that can inhibit the activity of FK-506 binding protein. Grades: ≥90% by HPLC. Molecular formula: C43H69NO12. Mole weight: 792.01.
8-epi Tacrolimus
Cas No. 129212-35-7.
8-Epitacrolimus
8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus. Group: Biochemicals. Alternative Names: (-)-8-epi-Tacrolimus; [3S-[3R*[E(1S*, 3S*, 4S*)], 4S*, 5R*, 8R*, 9E, 12R*, 14R*, 15S*, 16R*, 18S*, 19S*, 26aR*]]-5, 6, 8, 11, 12, 13, 14, 15, 16, 17, 18, 19, 24, 25, 26, 26a-Hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14, 16-dimethoxy-4, 10, 12, 18-tetramethyl-8-(2-propenyl)-15, 19-epoxy-3H-pyrido[2, 1-c][1, 4]oxaazacyclotricosine-1, 7, 20, 21(4H, 23H)-tetrone. Grades: Highly Purified. CAS No. 129212-35-7. Pack Sizes: 500ug. Molecular Formula: C??H??NO??, Molecular Weight: 804.02. US Biological Life Sciences.
Worldwide
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