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| Product | Description | |
|---|---|---|
| TAT 14 | TAT 14. Group: Biochemicals. Grades: Purified. CAS No. 1362661-34-4. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| TAT 14 | TAT 14 is an Nrf2 activator and inhibits Nrf2/Keap1 interaction with neuroprotective activity. TAT 14 has been shown to induce upregulation of Nrf2 pathway downstream gene expression including heme-oxygenase 1 and suppress LPS-induced TNF-α expression in THP-1 cells. Synonyms: TAT14; TAT-14; H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-leucyl-L-glutaminyl-L-leucyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-threonyl-glycyl-L-alpha-glutamyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-glutamine; TAT 14 Peptide (Nrf2 Activator III). Grade: ≥95%. CAS No. 1362661-34-4. Molecular formula: C137H230N48O39. Mole weight: 3173.59. |  |
| Nrf2 Activator III, TAT-14 Peptide, H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg~Leu-Gln-Leu-Asp-Glu-Glu-Thr-Gly-Glu-Phe-Leu-Pro-Ile-Gln-OH | A 14-mer peptide (LQLDEETGEFLPIQ) conjugated to cell-penetrating trans-activating transcriptional activator (TAT) sequence (YGRKKRRQRRRLQ) that targets the nuclear factor (erythroid-derived 2)-like 2 (Nrf2) binding site on Kelch-like ECH-associated protein 1 (Keap1). Competitively disrupts Nrf2-Keap1 interaction and stabilizes cytosolic Nrf2, and promotes its nuclear translocation and binding to the antioxidant response element (ARE). Exhibits anti-inflammatory properties and increases heme-oxygenase-1 gene expression (~75uM). Also shown to suppress LPS-induced TNF-a secretion in THP-1 monocytes (~ 37.5uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 1362661-34-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TAT-14 | TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1362661-34-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1328. |  |
| DOTATATE | DOTATATE is a radiolabeled somatostatin analog used in medical imaging and therapy for neuroendocrine tumors (NETs). DOTATATE is a peptide derivative that binds selectively to somatostatin receptors (mainly subtype 2), which are overexpressed on the surface of neuroendocrine tumor cells. This allows for specific targeting of these tumors. Synonyms: L-Threonine, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; L-Threonine, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide; DOTA-octreotate; DOTA-TATE; DOTA-[Tyr3]-Octreotide Acid; DOTA-(Tyr3)-octreotate. Grade: ≥95%. CAS No. 177943-88-3. Molecular formula: C65H90N14O19S2. Mole weight: 1435.63. | |
| N, N, N', N'-Tetra([1, 1'-biphenyl]-4-yl)[1, 1':4', 1''-terphenyl]-4, 4''-diamine | N, N, N', N'-Tetra([1, 1'-biphenyl]-4-yl)[1, 1':4', 1''-terphenyl]-4, 4''-diamine. Group: Organic light-emitting diode (oled) materials perovskite solar cell (psc) materials. Alternative Names: TaTm. CAS No. 952431-34-4. Product ID: 4-phenyl-N- (4-phenylphenyl) -N-[4-[4-[4- (4-phenyl-N- (4-phenylphenyl) anilino) phenyl]phenyl]phenyl]aniline. Molecular formula: 869.12. Mole weight: C66H48N2. C1=CC=C (C=C1)C2=CC=C (C=C2)N (C3=CC=C (C=C3)C4=CC=CC=C4)C5=CC=C (C=C5)C6=CC=C (C=C6)C7=CC=C (C=C7)N (C8=CC=C (C=C8)C9=CC=CC=C9)C1=CC=C (C=C1)C1=CC=CC=C1. InChI=1S/C66H48N2/c1-5-13-49 (14-6-1) 55-25-37-61 (38-26-55) 67 (62-39-27-56 (28-40-62) 50-15-7-2-8-16-50) 65-45-33-59 (34-46-65) 53-21-23-54 (24-22-53) 60-35-47-66 (48-36-60) 68 (63-41-29-57 (30-42-63) 51-17-9-3-10-18-51) 64-43-31-58 (32-44-64) 52-19-11-4-12-20-52/h1-48H. FRJIRSGTDSDPTM-UHFFFAOYSA-N. 95%+. |  |
| Relacorilant | Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a K i of 7.2 nM in HepG2 TAT assay, and also shows K i s of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively. Relacorilant has the potential for Cushings syndrome treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CORT 125134. CAS No. 1496510-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109042. | |
| TAT | TAT is a TAT peptide encoded by HIV-1 virus, which can increase the yields and solubility of heterologous proteins. Synonyms: Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2; (2S)-2-[(2S,8S,11S,14S,17S,20S)-2-Amino-11,14-bis(4-aminobutyl)-21-{[(1S)-1-{N-[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-hydroxy-1-imino-2-pentanyl]imino}-1-hydroxy-2-pentanyl]imino}-1-hydroxy-2-pentanyl]imidic acid}-3-imidicacidpropyl]imino}-8,17,20-tris(3-carbamimidamidopropyl)-3,6,9,12,15,18,21-heptahydroxy-1-(4-hydroxyphenyl)-4,7,10,13,16,19-hexaazahenicosa-3,6,9,12,15,18-hexaen-yl]-N1-[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-{[(2S)-5-carbamimidamido-1-hydroxy-1-imino-2-pentanyl]imino}-1-hydroxy-2-pentanyl]imino}-1-hydroxy-2-pentanyl]pentanediimidic acid; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-argininamide. Grade: ≥95% by HPLC. CAS No. 697226-52-1. Molecular formula: C64H119N33O13. Mole weight: 1558.85. | |
| Tat-beclin 1 | Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV)[1]. Uses: Scientific research. Group: Peptides. CAS No. 1423821-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P2260. | |
| TAT-C (48-57) | It is amino acids 48 to 57 fragment of TAT with an additional cysteine residue at the N-terminus. The peptide contains a protein transduction domain (PTD) that inhibits HSV-1 entry into the HIV Tat protein. The addition of cysteine residue to the N-terminus of the Tat-PTD (Tat-C peptide) improves the antiviral activity against HSV-1 and HSV-2. Tat-C acts extracellular and immediately blocks the entry of adsorptive virus without eluting virions. Synonyms: H-Cys-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; (Cys47)-HIV-1 tat Protein (47-57); L-cysteinyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine. Grade: ≥95%. CAS No. 627079-23-6. Molecular formula: C58H114N32O13S. Mole weight: 1499.82. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY has been found to be a HIF-1 dimerization inhibitor and could block protein-protein interaction of recombinant HIF-1α. Synonyms: TAT-cyclo-CLLFVY; 1446322-66-2; AKOS027470216; PD079835. Grade: ≥95% by HPLC. CAS No. 1446322-66-2. Molecular formula: C111H188N42O24S2. Mole weight: 2559.10. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY disrupts HIF-1α/HIF-1β protein-protein interaction with an IC 50 of 1.3 μM [1]. Uses: Scientific research. Group: Peptides. CAS No. 1446322-66-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1420. | |
| TAT-GluR23Y | TAT-GluR23Y is a cell penetrating peptide containing tyrosine residues. It inhibits the phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Synonyms: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Tyr-Lys-Glu-Gly-Tyr-Asn-Val-Tyr-Gly-OH; Tat-GluR23Y; L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-tyrosyl-L-lysyl-L-alpha-glutamyl-glycyl-L-tyrosyl-L-asparagyl-L-valyl-L-tyrosyl-glycine; TAT-GluA2 3Y. Grade: ≥95%. CAS No. 1404188-93-7. Molecular formula: C115H185N43O29. Mole weight: 2634.01. | |
| Tatsinine | Tatsinine is a potential natural compound in natural compound used for the research of various cancers. With its unique chemical structure, it has shown promising anti-tumor activity by inhibiting specific signaling pathways involved in cancer progression. Synonyms: 20-ethyl-16-methoxy-4-methylaconitane-1,7,8,9,14-pentol. Grade: 97.0%. CAS No. 90038-21-4. Molecular formula: C22H35NO6. Mole weight: 409.523. | |
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