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United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Tenofovir Disoproxil fumarate
Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tenofovir DF; Bis(POC)-PMPA fumarate; GS 4331 fumarate. CAS No. 202138-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13782.
Tenofovir Disoproxil Fumarate
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. Group: Biochemicals. Alternative Names: 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid 1,9-Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate; GS 4331-05; PMPA Prodrug. Grades: Highly Purified. CAS No. 202138-50-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C23H34N5O14P, Molecular Weight: 635.51. US Biological Life Sciences.
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Desmethyl Tenofovir Disoproxil Fumarate
Desmethyl Tenofovir Disoproxil Fumarate. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS007403. Format: Neat. Shipping: Room Temperature.
Desmethyl Tenofovir Disoproxil Fumarate
Desmethyl Tenofovir Disoproxil is a demethylated analogue and impurity of the antiviral Tenofovir Disoproxil Fumarate. Group: Biochemicals. Alternative Names: 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
(S)-Tenofovir Disoproxil Fumarate
(S)-Tenofovir Disoproxil Fumarate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1432630-26-6. Pack Sizes: 2.5MG. IUPAC Name: [[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate;(E)-but-2-enedioic acid. Molecular formula: C19H30N5O10P.C4H4O4. Mole weight: 635.51. Catalog: APS1432630266. SMILES: CC(C)OC(=O)OCOP(=O)(CO[C@@H](C)Cn1cnc2c(N)ncnc12)OCOC(=O)OC(C)C.OC(=O)\C=C\C(=O)O. Format: Neat. Shipping: Room Temperature.
(S)-Tenofovir Disoproxil Fumarate
The S-enatiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate. Group: Biochemicals. Alternative Names: 5-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Tenofovir Disoproxil-[d6] Fumarate
Tenofovir Disoproxil-[d6] Fumarate is a labelled metabolite of Tenofovir, a medication used in the prevention and treatment of HIV/AIDS. Synonyms: PMPA Prodrug-d6; Tenofovir DF-d6. Grade: 98%; >95% atom D. Molecular formula: C19H24D6N5O10P.C4H4O4. Mole weight: 641.55.
Tenofovir Disoproxil (fumarate) (Standard)
Tenofovir Disoproxil (fumarate) (Standard) is the analytical standard of Tenofovir Disoproxil (fumarate). This product is intended for research and analytical applications. Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tenofovir DF (Standard); Bis(POC)-PMPA (fumarate) (Standard); GS 4331 (fumarate) (Standard). CAS No. 202138-50-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13782R.
(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl benzoate, a pharmaceutical intermediate of great consequence, serves as a vital component in the synthesis of antiviral drugs. It has proven to be particularly effective in the development of Tenofovir Disoproxil Fumarate, a drug that upholds a significant role in the treatment of people living with HIV/AIDS. Molecular formula: C17H17FN2O6. Mole weight: 364.33.
Adefovir disoproxil
Adefovir disoproxil is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: O,O-Bis(isopropoxycarbonyloxymethyl) [(6-amino-9H-purin-9-yl)ethyloxy]methylphosphonate; Desmethyl Tenofovir Disoproxil; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide; (((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy)bis(methylene) isopropyl dicarbonate; [2-(6-aminopurin-9-yl)ethoxymethyl-(isopropoxycarbonyloxymethoxy)phosphoryl]oxymethyl isopropyl carbonate; [[2-(6-Amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid bis[(isopropoxycarbonyloxy)methyl] ester. Grade: ≥95%. CAS No. 365417-53-4. Molecular formula: C18H28N5O10P. Mole weight: 505.42.
Adefovir disoproxil 2-butenedioate
Adefovir disoproxil 2-butenedioate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, 2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide 2-Butenedioate; ((((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) but-2-enedioic acid; Desmethyl Tenofovir Disoproxoil 2-Butenedioate. Grade: ≥95%. CAS No. 1798422-29-3. Molecular formula: C22H32N5O14P. Mole weight: 621.49.
Adefovir disoproxil fumarate
Adefovir disoproxil fumarate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: Desmethyl Tenofovir Disoproxoil Fumarate; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide Fumarate; ((((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) fumarate. Grade: ≥95%. CAS No. 2251049-67-7. Molecular formula: C18H28N5O10P.C4H4O4. Mole weight: 621.49.
Chloromethyl Isopropyl Carbonate
Chloromethyl Isopropyl Carbonate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: CMIC; Carbonic acid, chloromethyl 1-methylethyl ester; Chloromethyl 1-methylethyl carbonate; [(Isopropyloxycarbonyl)oxy]methyl chloride; Isopropoxycarbonyloxymethyl chloride; Isopropyl chloromethyl carbonate. Grade: 95%. CAS No. 35180-01-9. Molecular formula: C5H9ClO3. Mole weight: 152.58.
Dimethyaminocarboxymethyl POC Tenofovir
Dimethyaminocarboxymethyl POC Tenofovir is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: (1-Methylethyl) (5RS)-5-{[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}-10-methyl-5,9-dioxo-2,4,6,8-tetraoxa-10-aza-5-λ5-phosphaundecanoate; ((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)oxy)methyl dimethylcarbamate; [(Dimethylcarbamoyl)oxy]methyl[(isopropoxycarbonyl)oxy]methyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate; Carbonic acid, [[[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl][[[(dimethylamino)carbonyl]oxy]methoxy]phosphinyl]oxy]methyl 1-methylethyl ester; Tenofovir Disoproxil Fumarate IP Impurity L. Grade: ≥95%. Molecular formula: C18H29N6O9P. Mole weight: 504.44.
GS-7340 fumarate
Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grade: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 59
(R)-9-(2-Hydroxypropyl)adenine
(R)-9-(2-Hydroxypropyl)adenine is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: (R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol; Hydroxypropyladenine; (R)-(+)-9-(2-Hydroxypropyl)adenine; D-(-)-9-(2-Hydroxypropyl)adenine; (αR)-6-Amino-α-methyl-9H-purine-9-ethanol; Desphosphoryl Tenofovir; (2R)-1-(6-aminopurin-9-yl)-2-propanol. Grade: ≥95%. CAS No. 14047-28-0. Molecular formula: C8H11N5O. Mole weight: 193.21.
(S)-9-[2-(Hydroxypropyl] Adenine
(S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-Tenofovir Disoproxil Fumarate (T018506). Group: Biochemicals. Alternative Names: (S)-9-(2-Hydroxypropyl)adenine; 9-[(2S)-2-Hydroxypropyl]adenine; L-(+)-9-(2-Hydroxypropyl)adenine; (αS)-6-Amino-α-methyl-9H-purine-9-ethanol. Grades: Highly Purified. CAS No. 14047-27-9. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
(S)-Tenofovir Disoproxil
(S)-Tenofovir Disoproxil is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: (S)-(((((1-(6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) Diisopropyl Dicarbonate; Tenofovir Disoproxil S-Enantiomer; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide; Bis(1-methylethyl) 5-{[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl}-5-oxo-2,4,6,8-tetraoxa-5-λ5-phosphanonanedioate; Tenofovir Disoproxil Fumarate IP Impurity G; Tenofovir disoproxil (S)-enantiomer. Grade: ≥95%. CAS No. 1280130-08-6. Molecular formula: C19H30N5O10P. Mole weight: 519.44.
(Z)-9-Propenyladenine
(Z)-9-Propenyladenine is a mutagenic impurity of tenofovir disoproxil fumarate. Tenofovir is a nucleotide analogue reverse transcriptase (NtART) inhibitor used as an antiretroviral drug. Synonyms: (Z)-Mutagenic Impurity of Tenofovir Disoproxil; (Z)-9-(prop-1-en-1-yl)-9H-purin-6-amine; 9-[(Z)-1-Propenyl]-9H-purine-6-amine. Grade: ≥97%. CAS No. 1464851-21-5. Molecular formula: C8H9N5. Mole weight: 175.19.
Diethylaminocarboxymethyl POC Tenofovir Fumarate
One impurity of Tenofovir Disoproxil, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: Diethylaminocarboxymethyl POC Tenofovir. Grade: > 95%. Molecular formula: C20H33N6O9P. C4H4O4. Mole weight: 648.56.
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