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TenofovirDisoproxilfumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tenofovir DF; Bis(POC)-PMPA fumarate; GS 4331 fumarate. CAS No. 202138-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13782.
TenofovirDisoproxilFumarate
Acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral. Group: Biochemicals. Alternative Names: 5-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-2,4,6,8-tetraoxa-5-phosphanonanedioic Acid 1,9-Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate; GS 4331-05; PMPA Prodrug. Grades: Highly Purified. CAS No. 202138-50-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C23H34N5O14P, Molecular Weight: 635.51. US Biological Life Sciences.
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TenofovirDisoproxilFumarate
TenofovirDisoproxilFumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate. Synonyms: GS-1278 DisoproxilFumarate; GS 1278 DisoproxilFumarate; GS1278 DisoproxilFumarate. Grades: >98%. CAS No. 202138-50-9. Molecular formula: C19H30N5O10P.C4H4O4. Mole weight: 635.51.
One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Grades: > 95%. Molecular formula: C15H24N5O8P. Mole weight: 433.36.
Desmethyl TenofovirDisoproxilFumarate
Desmethyl TenofovirDisoproxilFumarate. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS007403. Format: Neat. Shipping: Room Temperature.
Desmethyl TenofovirDisoproxilFumarate
Desmethyl TenofovirDisoproxil is a demethylated analogue and impurity of the antiviral TenofovirDisoproxilFumarate. Group: Biochemicals. Alternative Names: 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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rac-TenofovirDisoproxil Related Compound G Fumarate
rac-TenofovirDisoproxil Related Compound G Fumarate is an impurity of TenofovirDisoproxilFumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-8-methyl-5-(1-methylethoxy)-, 1-methylethyl ester, 5-oxide, (2E)-2-butenedioate (1:1); O-(Isopropoxycarbonyloxymethyl)-O-isopropyl-{[1-(6-amino-9H-purin-9-yl)propan-2-yloxy]}methylphosphonate fumarate salt; ( ( ( ( (1- (6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (isopropoxy)phosphoryl)oxy)methyl isopropyl carbonate fumarate; rac-Mono-POC Isopropyl Tenofovirfumarate. Grades: ≥95%. Molecular formula: C17H28N5O7P.C4H4O4. Mole weight: 561.49.
The S-enatiomeric impurity of the antiviral TenofovirDisoproxilFumarate. Group: Biochemicals. Alternative Names: 5-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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S-TenofovirDisoproxilFumarate
S-TenofovirDisoproxilFumarate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)- ( ( ( ( (1- (6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis (oxy))bis (methylene) diisopropyl dicarbonate fumarate; TenofovirDisoproxil USP Related Compound A. CAS No. 1432630-26-6. Molecular Formula: C23H34N5O14P. Mole Weight: 635.51. Catalog: APB1432630266.
TenofovirDisoproxil (fumarate) (Standard)
TenofovirDisoproxil (fumarate) (Standard) is the analytical standard of TenofovirDisoproxil (fumarate). This product is intended for research and analytical applications. TenofovirDisoproxilfumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tenofovir DF (Standard); Bis(POC)-PMPA (fumarate) (Standard); GS 4331 (fumarate) (Standard). CAS No. 202138-50-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13782R.
TenofovirDisoproxil Impurity EOC-POCPMPA Fumarate
Cas No. 1422284-17-0.
TenofovirDisoproxil Related Compound G Fumarate
TenofovirDisoproxil Related Compound G Fumarate is an impurity of TenofovirDisoproxilFumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-8-methyl-5-(1-methylethoxy)-, 1-methylethyl ester, 5-oxide, (8R)-, (2E)-2-butenedioate (1:1); O-(Isopropoxycarbonyloxymethyl)-O-isopropyl-{(R)-[1-(6-amino-9H-purin-9-yl)propan-2-yloxy]}methylphosphonate fumarate salt; ( ( ( ( ( (R)-1- (6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (isopropoxy)phosphoryl)oxy)methyl isopropyl carbonate fumarate; Mono-POC Isopropyl Tenofovirfumarate. Grades: ≥95%. CAS No. 1422284-15-8. Molecular formula: C17H28N5O7P.C4H4O4. Mole weight: 561.48.
TenofovirDisoproxil USP Related Compound G Fumarate
TenofovirDisoproxil USP Related Compound G Fumarate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1422284-15-8. Molecular Formula: C21H32N5O11P. Mole Weight: 561.48. Catalog: APB1422284158.
(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl benzoate, a pharmaceutical intermediate of great consequence, serves as a vital component in the synthesis of antiviral drugs. It has proven to be particularly effective in the development of TenofovirDisoproxilFumarate, a drug that upholds a significant role in the treatment of people living with HIV/AIDS. Molecular formula: C17H17FN2O6. Mole weight: 364.33.
Adefovir disoproxil
Adefovir disoproxil is an impurity of TenofovirDisoproxilFumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: O,O-Bis(isopropoxycarbonyloxymethyl) [(6-amino-9H-purin-9-yl)ethyloxy]methylphosphonate; Desmethyl TenofovirDisoproxil; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide; ( ( (2- (6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy)bis (methylene) isopropyl dicarbonate; [2- (6-aminopurin-9-yl) ethoxymethyl- (isopropoxycarbonyloxymethoxy) phosphoryl]oxymethyl isopropyl carbonate; [[2-(6-Amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid bis[(isopropoxycarbonyloxy)methyl] ester. Grades: ≥95%. CAS No. 365417-53-4. Molecular formula: C18H28N5O10P. Mole weight: 505.42.
Adefovir disoproxilfumarate
Adefovir disoproxilfumarate is an impurity of TenofovirDisoproxilFumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: Desmethyl Tenofovir Disoproxoil Fumarate; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide Fumarate; ( ( ( (2- (6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy))bis (methylene) diisopropyl bis(carbonate) fumarate. Grades: ≥95%. CAS No. 2251049-67-7. Molecular formula: C18H28N5O10P.C4H4O4. Mole weight: 621.49.
GS-7340 fumarate
Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovirdisoproxilfumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir / cobicistat / emtricitabine / tenofovirdisoproxilfumarate to elvitegravir / cobicistat / emtricitabine / tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2- ( ( (S)- ( ( ( (R)-1- (6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grades: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 592.54.
(R)-9-(2-Hydroxypropyl)adenine
(R)-9-(2-Hydroxypropyl)adenine is an impurity of TenofovirDisoproxilFumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: (R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol; Hydroxypropyladenine; (R)-(+)-9-(2-Hydroxypropyl)adenine; D-(-)-9-(2-Hydroxypropyl)adenine; (αR)-6-Amino-α-methyl-9H-purine-9-ethanol; Desphosphoryl Tenofovir; (2R)-1-(6-aminopurin-9-yl)-2-propanol. Grades: ≥95%. CAS No. 14047-28-0. Molecular formula: C8H11N5O. Mole weight: 193.21.
(S)-9-[2-(Hydroxypropyl] Adenine
(S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-TenofovirDisoproxilFumarate (T018506). Group: Biochemicals. Alternative Names: (S)-9-(2-Hydroxypropyl)adenine; 9-[(2S)-2-Hydroxypropyl]adenine; L-(+)-9-(2-Hydroxypropyl)adenine; (αS)-6-Amino-α-methyl-9H-purine-9-ethanol. Grades: Highly Purified. CAS No. 14047-27-9. Pack Sizes: 250mg. US Biological Life Sciences.
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Tenofovir Impurity 2
Tenofovir Impurity 2 is an impurity of TenofovirDisoproxilFumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 9-(Prop-1-enyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(1-propen-1-yl)-; TenofovirDisoproxilFumarate IP Impurity K; 9-(1-Propen-1-yl)-9H-purin-6-amine; 9-(1-Propenyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(1-propenyl)-; Adenine, 9-propenyl-. Grades: ≥95%. CAS No. 4121-40-8. Molecular formula: C8H9N5. Mole weight: 175.19.
Diethylaminocarboxymethyl POC TenofovirFumarate
One impurity of TenofovirDisoproxil, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: Diethylaminocarboxymethyl POC Tenofovir. Grades: > 95%. Molecular formula: C20H33N6O9P. C4H4O4. Mole weight: 648.56.
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