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Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5'-triphosphate. Synonyms: GS-1278 Disoproxil Fumarate; GS 1278 Disoproxil Fumarate; GS1278 Disoproxil Fumarate. Grades: >98%. CAS No. 202138-50-9. Molecular formula: C19H30N5O10P.C4H4O4. Mole weight: 635.51.
One impurity of Tenofovir, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Grades: > 95%. Molecular formula: C15H24N5O8P. Mole weight: 433.36.
Desmethyl Tenofovir Disoproxil Fumarate
Desmethyl Tenofovir Disoproxil Fumarate. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS007403. Format: Neat. Shipping: Room Temperature.
Desmethyl Tenofovir Disoproxil Fumarate
Desmethyl Tenofovir Disoproxil is a demethylated analogue and impurity of the antiviral Tenofovir Disoproxil Fumarate. Group: Biochemicals. Alternative Names: 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide (2E)-2-Butenedioate. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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rac-Tenofovir Disoproxil Related Compound G Fumarate
rac-Tenofovir Disoproxil Related Compound G Fumarate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-8-methyl-5-(1-methylethoxy)-, 1-methylethyl ester, 5-oxide, (2E)-2-butenedioate (1:1); O-(Isopropoxycarbonyloxymethyl)-O-isopropyl-{[1-(6-amino-9H-purin-9-yl)propan-2-yloxy]}methylphosphonate fumarate salt; ( ( ( ( (1- (6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (isopropoxy)phosphoryl)oxy)methyl isopropyl carbonate fumarate; rac-Mono-POC Isopropyl Tenofovir fumarate. Grades: ≥95%. Molecular formula: C17H28N5O7P.C4H4O4. Mole weight: 561.49.
The S-enatiomeric impurity of the antiviral Tenofovir Disoproxil Fumarate. Group: Biochemicals. Alternative Names: 5-[[(1S)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]-. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
S-Tenofovir Disoproxil Fumarate
S-Tenofovir Disoproxil Fumarate. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)- ( ( ( ( (1- (6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis (oxy))bis (methylene) diisopropyl dicarbonate fumarate; Tenofovir Disoproxil USP Related Compound A. CAS No. 1432630-26-6. Molecular Formula: C23H34N5O14P. Mole Weight: 635.51. Catalog: APB1432630266.
Tenofovir Disoproxil (fumarate) (Standard)
Tenofovir Disoproxil (fumarate) (Standard) is the analytical standard of Tenofovir Disoproxil (fumarate). This product is intended for research and analytical applications. Tenofovir Disoproxil fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tenofovir DF (Standard); Bis(POC)-PMPA (fumarate) (Standard); GS 4331 (fumarate) (Standard). CAS No. 202138-50-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13782R.
Tenofovir Disoproxil Related Compound G Fumarate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 2,4,7-Trioxa-5-phosphanonanoic acid, 9-(6-amino-9H-purin-9-yl)-8-methyl-5-(1-methylethoxy)-, 1-methylethyl ester, 5-oxide, (8R)-, (2E)-2-butenedioate (1:1); O-(Isopropoxycarbonyloxymethyl)-O-isopropyl-{(R)-[1-(6-amino-9H-purin-9-yl)propan-2-yloxy]}methylphosphonate fumarate salt; ( ( ( ( ( (R)-1- (6-Amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (isopropoxy)phosphoryl)oxy)methyl isopropyl carbonate fumarate; Mono-POC Isopropyl Tenofovir fumarate. Grades: ≥95%. CAS No. 1422284-15-8. Molecular formula: C17H28N5O7P.C4H4O4. Mole weight: 561.48.
Tenofovir Disoproxil USP Related Compound G Fumarate
Tenofovir Disoproxil USP Related Compound G Fumarate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1422284-15-8. Molecular Formula: C21H32N5O11P. Mole Weight: 561.48. Catalog: APB1422284158.
(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl benzoate, a pharmaceutical intermediate of great consequence, serves as a vital component in the synthesis of antiviral drugs. It has proven to be particularly effective in the development of Tenofovir Disoproxil Fumarate, a drug that upholds a significant role in the treatment of people living with HIV/AIDS. Molecular formula: C17H17FN2O6. Mole weight: 364.33.
Adefovir disoproxil
Adefovir disoproxil is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: O,O-Bis(isopropoxycarbonyloxymethyl) [(6-amino-9H-purin-9-yl)ethyloxy]methylphosphonate; Desmethyl Tenofovir Disoproxil; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide; ( ( (2- (6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy)bis (methylene) isopropyl dicarbonate; [2- (6-aminopurin-9-yl) ethoxymethyl- (isopropoxycarbonyloxymethoxy) phosphoryl]oxymethyl isopropyl carbonate; [[2-(6-Amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid bis[(isopropoxycarbonyloxy)methyl] ester. Grades: ≥95%. CAS No. 365417-53-4. Molecular formula: C18H28N5O10P. Mole weight: 505.42.
Adefovir disoproxil fumarate
Adefovir disoproxil fumarate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: Desmethyl Tenofovir Disoproxoil Fumarate; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide Fumarate; ( ( ( (2- (6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis (oxy))bis (methylene) diisopropyl bis(carbonate) fumarate. Grades: ≥95%. CAS No. 2251049-67-7. Molecular formula: C18H28N5O10P.C4H4O4. Mole weight: 621.49.
GS-7340 fumarate
Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel prodrug of tenofovir. It is under development by Gilead Sciences for use in the treatment of HIV infection. Closely related to the commonly used reverse-transcriptase inhibitor tenofovir disoproxil fumarate (Viread), Tenofovir alafenamide has greater antiviral activity and better distribution into lymphoid tissues than that agent. Gilead has announced a phase 3 clinical trial evaluating a single-tablet regimen combining GS-7340 with cobicistat, emtricitabine and elvitegravir and plans to coformulate the drug with cobicistat, emtricitabine and the protease inhibitor darunavir. In a 48 week study comparing Elvitegravir / cobicistat / emtricitabine / tenofovir disoproxil fumarate to elvitegravir / cobicistat / emtricitabine / tenofovir alafenamide fumarate, the results showed the prodrug to be non inferior to the established agent, but at much lower dosages and with lower incidence of adverse side effects such as impaired kidney function. Synonyms: GS-7340 fumarate; GS 7340 fumarate; GS7340 fumarate; (S)-isopropyl 2- ( ( (S)- ( ( ( (R)-1- (6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) (phenoxy)phosphoryl)amino)propanoate fumarate; TAF; GS734; GS-734; GS 7340; Tenofovir alafenamide fumarate; trade name: Genvoya. Grades: >98%. CAS No. 379270-38-9. Molecular formula: C25H33N6O9P. Mole weight: 592.54.
(R)-9-(2-Hydroxypropyl)adenine
(R)-9-(2-Hydroxypropyl)adenine is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: (R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol; Hydroxypropyladenine; (R)-(+)-9-(2-Hydroxypropyl)adenine; D-(-)-9-(2-Hydroxypropyl)adenine; (αR)-6-Amino-α-methyl-9H-purine-9-ethanol; Desphosphoryl Tenofovir; (2R)-1-(6-aminopurin-9-yl)-2-propanol. Grades: ≥95%. CAS No. 14047-28-0. Molecular formula: C8H11N5O. Mole weight: 193.21.
(S)-9-[2-(Hydroxypropyl] Adenine
(S)-9-[2-(Hydroxypropyl] Adenine is an inhibitor of adenosine deaminase. (S)-9-[2-(Hydroxypropyl] Adenine is used in the preparation of antiviral acyclic nucleoside thiophosphonates such as (S)-Tenofovir Disoproxil Fumarate (T018506). Group: Biochemicals. Alternative Names: (S)-9-(2-Hydroxypropyl)adenine; 9-[(2S)-2-Hydroxypropyl]adenine; L-(+)-9-(2-Hydroxypropyl)adenine; (αS)-6-Amino-α-methyl-9H-purine-9-ethanol. Grades: Highly Purified. CAS No. 14047-27-9. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Tenofovir Impurity 2
Tenofovir Impurity 2 is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 9-(Prop-1-enyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(1-propen-1-yl)-; Tenofovir Disoproxil Fumarate IP Impurity K; 9-(1-Propen-1-yl)-9H-purin-6-amine; 9-(1-Propenyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(1-propenyl)-; Adenine, 9-propenyl-. Grades: ≥95%. CAS No. 4121-40-8. Molecular formula: C8H9N5. Mole weight: 175.19.
Diethylaminocarboxymethyl POC Tenofovir Fumarate
One impurity of Tenofovir Disoproxil, which is an acyclic phosphonate nucleotide derivative, could be used in antiviral treatment as an everse transcriptase inhibitor. Synonyms: Diethylaminocarboxymethyl POC Tenofovir. Grades: > 95%. Molecular formula: C20H33N6O9P. C4H4O4. Mole weight: 648.56.
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