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Terlipressin is an analog of vasopressin and a partial agonist of the vasopressin V1A receptor (Ki = 0.85 μM). It has been used as a vasoactive drug in the management of low blood pressure. Synonyms: Vasopressin, N-(glycylglycylglycyl)-8-L-lysine-, acetate (1:x); Vasopressin, N-(glycylglycylglycyl)-8-L-lysine-, acetate (salt); H-Gly-Gly-Gly-L-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.C2H4O2; glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide acetate. Grades: ≥95%. CAS No. 914453-96-6. Molecular formula: C52H74N16O15S2.xC2H4O2. Mole weight: 1227.38 (free base).
Terlipressin Acetate
Vasopressin analog; vasoactive agent. Terlipressin is commonly used to stop bleeding of varices in the oesophagus. Varices are fragile distended veins that can occur in various parts of the body such as the oesophagus. This is caused by an increase in blood pressure in certain diseases such as severe liver disease. These fragile varices can rupture and lead to life threatening bleeding. Terlipressin is therefore given to narrow blood vessels, and so restricting blood flow to the varices and stopping the bleeding. When injected into the bloodstream, terlipressin acetate is broken down to release lysine vasopressin. This acts on the walls of the blood vessels, causing them to narrow and restrict the blood flow to the affected veins so that bleeding is reduced.Sequence:[Cys4-Cys9] Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2. Group: Biochemicals. Alternative Names: [Cys4-Cys9] Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2; 1-Triglycyl-8-lysine Vasopressin Diacetate Salt; 130: PN: WO2010033207 SEQID: 171 claimed protein Diacetate Salt; Glycylpressin Diacetate Salt; Glypressin Diacetate Salt; Nα-Gly-Gly-Gly-8-Lys-vasopressin Diacetate Salt; Nα-Glycyl-glycyl-glycyl-[. Grades: Highly Purified. CAS No. 14636-12-5. Pack Sizes: 50mg, 100mg, 250mg. Molecular Formula: C52H74N16O15S2·C2H4O2, Molecular Weight: 1227.37. US Biological Life Sciences.
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S) -1-[ (4R, 7S, 10S, 13S, 16S, 19S) -19-[[2-[[2-[ (2-aminoacetyl) amino]acetyl]amino]acetyl]amino]-7- (2-amino-2-oxoethyl) -10- (3-amino-3-oxopropyl) -13-benzyl-16-[ (4-hydroxyphenyl) methyl]-6, 9, 12, 15, 18-pentaoxo-1, 2-dithia-5, 8, 11, 14, 17-pentazacycloicosane-4-carbonyl]-N-[ (2S) -6-amino-1-[ (2-amino-2-oxoethyl) amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-D-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Grades: >98%. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base).
D-Gln(7)-Terlipressin Trifluoroacetic Acid Salt
D-Gln(7)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S) -1-[ (4R, 7S, 10R, 13S, 16S, 19R) -19-[[2-[[2-[ (2-aminoacetyl) amino]acetyl]amino]acetyl]amino]-7- (2-amino-2-oxoethyl) -10- (3-amino-3-oxopropyl) -13-benzyl-16-[ (4-hydroxyphenyl) methyl]-6, 9, 12, 15, 18-pentaoxo-1, 2-dithia-5, 8, 11, 14, 17-pentazacycloicosane-4-carbonyl]-N-[ (2S) -6-amino-1-[ (2-amino-2-oxoethyl) amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-Cys(1)-Tyr-Phe-D-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-D-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base).
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