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Vasopressin analog; vasoactive agent. Terlipressin is commonly used to stop bleeding of varices in the oesophagus. Varices are fragile distended veins that can occur in various parts of the body such as the oesophagus. This is caused by an increase in blood pressure in certain diseases such as severe liver disease. These fragile varices can rupture and lead to life threatening bleeding. Terlipressin is therefore given to narrow blood vessels, and so restricting blood flow to the varices and stopping the bleeding. When injected into the bloodstream, terlipressin acetate is broken down to release lysine vasopressin. This acts on the walls of the blood vessels, causing them to narrow and restrict the blood flow to the affected veins so that bleeding is reduced.Sequence:[Cys4-Cys9] Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2. Group: Biochemicals. Alternative Names: [Cys4-Cys9] Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2; 1-Triglycyl-8-lysine Vasopressin Diacetate Salt; 130: PN: WO2010033207 SEQID: 171 claimed protein Diacetate Salt; Glycylpressin Diacetate Salt; Glypressin Diacetate Salt; Nα-Gly-Gly-Gly-8-Lys-vasopressin Diacetate Salt; Nα-Glycyl-glycyl-glycyl-[. Grades: Highly Purified. CAS No. 14636-12-5. Pack Sizes: 50mg, 100mg, 250mg. Molecular Formula: C52H74N16O15S2·C2H4O2, Molecular Weight: 1227.37. US Biological Life Sciences.
Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels. Synonyms: Vasopressin, 8-L-lysine-, monoacetate (salt); Des-(1-3)-terlipressin acetate salt; Terlipressin EP Impurity C acetate salt; Des-Gly1-Gly2 Gly3 Terlipressin acetate salt; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2.C2H4O2 (Disulfide bridge: Cys1-Cys6); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide acetate salt; Des-1,2,3-Triglycine-Terlipressin acetate salt; 8-L-Lysine vasopressin acetate salt; L-Lysine vasopressin acetate salt; Vasopressin-8-lysine acetate salt. Grade: ≥95%. CAS No. 83968-49-4. Molecular formula: C48H69N13O14S2. Mole weight: 1116.27.
Ac-Gly1-Terlipressin
An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Ac-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4&Cys9 bridge); N1-Acetylterlipressin; Ac-GGGCYFQNCPKG-NH2(Cys4&Cys9 bridge); Terlipressin EP Impurity D; Ac-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys4-Cys9); N-Acetyl-glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide; [Ac-Gly1]Terlipressin; Terlipressin Impurity D; N-Terminal acetyl Terlipressin [Ac-TLY]. Grade: ≥95%. Molecular formula: C54H76N16O16S2. Mole weight: 1269.42.
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt
D-Cys(4)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S)-1-[(4R,7S,10S,13S,16S,19S)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-D-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-D-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Grade: >98%. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base).
D-Gln(7)-Terlipressin Trifluoroacetic Acid Salt
D-Gln(7)-Terlipressin Trifluoroacetic Acid Salt is an impurity of Terlipressin, which is a partial agonist of the vasopressin V1A receptor used as a vasoactive drug in the management of low blood pressure. Synonyms: (2S)-1-[(4R,7S,10R,13S,16S,19R)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]pyrrolidine-2-carboxamide Trifluoroacetic Acid Salt; H-Gly-Gly-Gly-Cys(1)-Tyr-Phe-D-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2.TFA; glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-D-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide TFA. Molecular formula: C52H74N16O15S2.xC2HF3O2. Mole weight: 1227.37 (free base).
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