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A labeled intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A intermediate in the synthesis of Amprenavir, a selective HIV protease inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
(2aR, 4aS, 4bS, 10aR, 10bS, 11S, 12aS, 14aR) -11, 14a-dihydroxy-10a-methyl-1, 4, 4a, 4b, 5, 6, 9, 10, 10a, 10b, 11, 12, 13, 14a-tetradecahydronaphtho [2', 1': 4, 5]indeno [1, 7a-c]oxeto [3, 2-b]furan-8 (3H) -one is an intermediate in the synthesis of 18-Hydroxycortisol whiis a derivative of Cortisol (H714615), frequently referred to as the stress hormone, is released into the bloodstream during periods of stress. Cortisol also has effects on enhancing memory with regards to emotions during stressful events. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C21H28O5. US Biological Life Sciences.
(2-chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methanone is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: (2-Chloro-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methanone; (1S)-1,5-Anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydro-3-furanyloxy]benzoyl}phenyl)-D-glucitol. CAS No. 2125472-55-9. Molecular formula: C23H25ClO8. Mole weight: 464.89.
2-Hydroxy-2,3-tetrahydrofuranyl Entecavir is an impurity of Entecavir. Group: Biochemicals. Alternative Names: 2-Amino-9-((3aS,4S,6S)-3a,6-dihydroxyhexahydro-1H-cyclopenta[c]furan-4-yl)-1H-purin-6(9H)-one. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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2-Hydroxy-2,3-tetrahydrofuranyl Entecavir (Mixture of Diastereomers)
2-Hydroxy-2,3-tetrahydrofuranyl Entecavir is an Entecavir impurity. Synonyms: 2-Amino-9-((3aS,4S,6S)-3a,6-dihydroxyhexahydro-1H-cyclopenta[c]furan-4-yl)-1H-purin-6(9H)-one. Grades: 99%. Molecular formula: C12H15N5O4. Mole weight: 293.28.
(2R,3S,5S)-Tetrahydro-3-hydroxy-5-(2-propen-1-yl)-2-furanmethanol, an essential precursor in the production of various pharmacological agents, exhibits promising potential in the treatment of neurodegenerative maladies such as Alzheimer's and Parkinson's disease. Its diverse application and utility in synthesizing antiviral and anticancer drugs further highlight the significance of this compound in medicinal chemistry. CAS No. 1057653-79-8. Molecular formula: C8H14O3. Mole weight: 158.19.
(2R)-Tetrahydro-2-furanmethanamine Hydrochloride
(2R)-Tetrahydro-2-furanmethanamine is a stereoisomer of Tetrahydro-2-furanmethanamine (T293545) which is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Tetrahydro-2-furanmethanamine (T293545) is also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 7175-80-6. Pack Sizes: 1g, 10g. Molecular Formula: C5H11NO HCl. US Biological Life Sciences.
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(2S)-Tetrahydro-2-furanmethanamine Hydrochloride
(2S)-Tetrahydro-2-furanmethanamine Hydrochloride is a stereoisomeric salt of Tetrahydro-2-furanmethanamine (T293545) which is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Tetrahydro-2-furanmethanamine (T293545) is also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 21801-94-5. Pack Sizes: 100mg, 500mg. Molecular Formula: C5H12ClNO. US Biological Life Sciences.
Methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-α-D-glucopyranoside is a remarkable compound, used in studying a myriad of ailments such as tumors. Synonyms: (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol; (2S,3R,4S,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol; Methoxy empagliflozin; Methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-alpha-D-glucopyranoside; 1-Methoxy Empagliflozin; UCE3CY4NYM; (2S,3R,4S,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol; alpha-D-Glucopyranoside, methyl 1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-; (3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)-2-methoxytetrahydro-2H-pyran-3,4,5-triol. CAS No. 1279691-36-9. Molecular formula: C24H29ClO8. Mole weight: 480.93.
rac 5-(3-Pyridyl)tetrahydro-2-furanone
A metabolite of Nicotine. Group: Biochemicals. Alternative Names: Dihydro-5-(3-pyridinyl)-2(3H)-furanone; (+/-) -5- (3-Pyridyl) tetrahydrofuranone-2; 4-Hydroxy-4-(3-pyridyl)butyric Acid γ-Lactone; 5- (3-Pyridyl) tetrahydrofuran-2-one. Grades: Highly Purified. CAS No. 20971-79-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
(S) -5-Oxo-2-tetrahydrofurancarboxylic Acid
(S) -5-Oxo-2-tetrahydrofurancarboxylic Acid. Group: Biochemicals. Alternative Names: (2S)-Tetrahydro-5-oxo-2-furancarboxylic Acid; (S) - ( + ) -5-Oxo-2-tetrahydrofurancarboxylic Acid; (2S)-Tetrahydro-5-oxofuran-2-carboxylic Acid; (S)-Tetrahydro-5-oxo-2-furancarboxylic Acid; 5S-(+)-Butyrolactone Carboxylic Acid. Grades: Highly Purified. CAS No. 21461-84-7. Pack Sizes: 100mg. US Biological Life Sciences.
1,1,3,3-Tetrabromoacetone is an intermediate in the synthesis of 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-13C5, which is an isotope labelled Mutagen X (MX) is a chlorinated furanone that accounts for more of the mutagenic activity of drinking water than any other disinfection byproduct. DNA damages provoked by the six mutagens (furylframide, MX, 4-nitroquinoline N-oxide, sodium azide, 1-nitropyrene, and captan) used in the present study have been known to subject to the nucleotide excision repair system. Group: Biochemicals. Grades: Highly Purified. CAS No. 22612-89-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C3H2Br4O. US Biological Life Sciences.
Worldwide
12-Ethoxynimbolinin B
12-Ethoxynimbolinin B is a limonoid compound. Limonoids are a class of tetranortriterpenoids with structural diversity and wide range of bioactivities, including insect antifeedant activity, and antimicrobial, antiprotozoal, anti-inflammatory, and anticancer activities. Synonyms: 2-Propenoic acid, 3-phenyl-, (2R, ?3aS, ?5R, ?6aR, ?6bR, ?7S, ?9R, ?9aR, ?11aR, ?12S, ?12aR)?-9-(acetyloxy)?-5-ethoxy-2-(3-furanyl)?-3, ?3a, ?6, ?6a, ?6b, ?7, ?8, ?9, ?9a, ?10, ?11a, ?11b, ?12, ?12a-tetradecahydro-12-hydroxy-1, ?6b, ?9a, ?12a-tetramethyl-2H, ?5H-cyclopent[a]?isobenzofuro[7, ?1-gh]?[3]?benzoxepin-7-yl ester, (2E)?-. Grades: > 98%. CAS No. 1019854-60-4. Molecular formula: C39H48O9. Mole weight: 660.79.
1-(3-beta-Amino-2,3-dideoxy-beta-D-threopenta-furanosyl)thymine is a nucleoside analogue used in the treatment of HIV-1 infected patients in combination with other antiretroviral drugs. It specifically targets the reverse transcriptase enzyme of the virus, preventing it from replicating and reducing viral load. Synonyms: 3'-beta-Amino-3'-deoxy thymidine; Thymidine, 3'-amino-3'-deoxy-; 1-((2R,4R,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-(3'-amino-2',3'-dideoxy-β-D-xylofuranosyl)thymidine; 1-(3-Amino-2,3-dideoxy-β-D-threo-pentofuranosyl)thymine. Grades: ≥95%. CAS No. 73971-79-6. Molecular formula: C10H15N3O4. Mole weight: 241.24.
1-(3'-O-[4,4'-Dimethoxytrityl]-alpha-L-threofuranosyl)-thymine is a nucleoside analog commonly used in the development of antiviral and antitumor drugs. It has been found to effectively treat viral infections such as HIV and hepatitis B or C, as well as different types of cancer. Its mechanism of action involves inhibiting viral replication and inducing apoptosis in cancer cells. Synonyms: 3'-O-DMT-T-TNA; 1-(3'-O-[4,4'-dimethoxytrityl]-α-L-threofuranosyl)-thymine; 1-{3'-O-[(4'',4'''-dimethoxytriphenyl)methyl]-α-L-threofuranosyl}thymine; 1-{(2R,3R,4S)-4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-3-hydroxy-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 325683-89-4. Molecular formula: C30H30N2O7. Mole weight: 530.57.
16-Hydroxycleroda-3,13-dien-15,16-olide
16-Hydroxycleroda-3,13-dien-15,16-olide is extracted from the unripe fruits of Polyalthia longifolia var. pendula. It is used as a candidate for autophagy inducers which can cause cell death in an alternative or supplement medicine for cancer therapy. It displays promising NO inhibitory activity at 10 ug/mL and shows anti-inflammatory activity. It induces apoptosis in CML K562 cells and regulates the expression of histone-modifying enzymes PRC2 complex. Synonyms: 5-Hydroxy-4-[2-[[(1S)-1,2,3,4,4a,7,8,8abeta-octahydro-1alpha,2alpha,4aalpha,5-tetramethylnaphthalen]-1-yl]ethyl]furan-2(5H)-one. Grades: 98.0%. CAS No. 141979-19-3. Molecular formula: C20H30O3. Mole weight: 318.45.
16(R)-AFP 07
16(R)-AFP 07 is an epimer of AFP 07, a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM). Synonyms: (5E)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4R)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 773825-80-2. Molecular formula: C22H30F2O5. Mole weight: 412.5.
1-Hydroxy Empagliflozin is an impurity of Empagliflozin, a medication indicated for type 2 diabetes treatment. Synonyms: 1-C-[4-Chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-α-D-glucopyranose; (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol. CAS No. 1279691-35-8. Molecular formula: C23H27ClO8. Mole weight: 466.91.
(1r*,2s*)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadienyl 2,5-dihydro-β-hydroxy-4-methyl-2,5-dioxo-3-furanpropanoic ac
2,2'-Methylene Bis[Ranitidine]. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ranitidine formaldehyde adduct (AH24065), Ranitidine Imp. I (EP),Ranitidine Hydrochloride Imp. I (EP), 2,2'-Methylenebis[N-[2-[[[5-[(dimethyl-amino)methyl]furan-2-yl]methyl]sulphanyl]ethyl]-N'-methyl-2-nitroethene-1,1-diamine], AH 24065A, Ph Eur Ranitidine Impurity I, formaldehyde adduct (AH 24065A). CAS No. 207592-21-0. IUPAC Name: (1E,4E)-1-N',5-N'-bis[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N,5-N-dimethyl-2,4-dinitropenta-1,4-diene-1,1,5,5-tetramine. Molecular Formula: C27H44N8O6S2. Mole Weight: 640.82. Catalog: APS207592210. SMILES: CN\C (=C (\C\C (=C (\NC)/NCCSCc1oc (CN (C)C)cc1)\[N+] (=O)[O-])/[N+] (=O)[O-])\NCCSCc2oc (CN (C)C)cc2. Format: Neat.
2,3,4,5-Tetradehydro alfuzosin hydrochloride
2,3,4,5-Tetradehydro alfuzosin hydrochloride. Group: Biochemicals. Alternative Names: N-[3-[ (4-Amino-6, 7-dimethoxy-2-quinazolinyl) methylamino]propyl]-2-furancarboxamide hydrochloride; Alfuzosin impurity A. Grades: Highly Purified. CAS No. 98902-29-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C19H24ClN5O4. US Biological Life Sciences.
Worldwide
2,3,4,5-Tetradehydro Alfuzosin Hydrochloride
2,3,4,5-Tetradehydro Alfuzosin Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]-, hydrochloride (1:1), 2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]-, monohydrochloride (9CI), N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]furan-2-carboxamide hydrochloride, 2,3,4,5-Tetradehydroalfuzosin hydrochloride. CAS No. 98902-29-5. IUPAC Name: N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)-methylamino]propyl]furan-2-carboxamide;hydrochloride. Molecular Formula: C19H23N5O4.ClH. Mole Weight: 421.88. Catalog: APS98902295. SMILES: Cl. COc1cc2nc (nc (N)c2cc1OC)N (C)CCCNC (=O)c3occc3. Format: Neat.
2'-Amino-2'-deoxyadenosine
It is produced by the strain of Actinomadura sp. No. SA-4427. It has anti-mycoplasma and anti-tumor effects. Synonyms: Hugamycin; 2'-Deoxy-2'-aminoadenosine; CHEMBL133809; 4-Amino-5-(6-amino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol; 2AD; 2-Amino-2-deoxyadenosine; 9-(2'-Amino-2'-deoxy-β-D-ribofuranosyl)-adenine. Grades: 98%. CAS No. 10414-81-0. Molecular formula: C10H14N6O3. Mole weight: 266.26.
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine is a highly effective antiviral compound widely employed in the field of biomedicine, holding potential in combating viral infections primarily induced by the notorious Herpes simplex virus (HSV) and Varicella-zoster virus (VZV). Significantly impeding viral DNA synthesis, replication, and protein biosynthesis, this remarkable compound facilitates in-depth investigation of innovative antiviral approaches and the advancement of therapeutic interventions targeting HSV and VZV-associated ailments. Synonyms: 6-S-Allyl-6-thio-guanosine; S-allyl-6-thio-guanosine; (2R,3R,4S,5R)-2-(6-Allylsulfanyl-2-amino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol; 2-Amino-6-allylmercapto-9-β-D-ribofuranosyl-purine. Grades: ≥95%. CAS No. 92104-54-6. Molecular formula: C13H17N5O4S. Mole weight: 339.37.
2'-Bromo-2'-deoxy-5-fluorouridine
2'-Bromo-2'-deoxy-5-fluorouridine is a nucleoside analog that interferes with RNA and DNA synthesis, used as an antineoplastic agent against certain types of cancer including pancreatic, colorectal and breast cancer. It can also be used clinically as a prodrug, in combination with other anticancer agents, to increase their efficacy. Synonyms: Uridine, 2'-bromo-2'-deoxy-5-fluoro-; 5-Fluor-2'-brom-2'-deoxyuridine; 1-((2R,3R,4R,5R)-3-Bromo-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-fluoro-1H-pyrimidine-2,4-dione; 1-[(2R,3R,4R,5R)-3-bromo-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidine-2,4-dione. Grades: ≥95%. CAS No. 32791-82-5. Molecular formula: C9H10BrFN2O5. Mole weight: 325.09.
2-Chloro-6-(furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside, a nucleoside analogue, functions by halting cancer cell growth through DNA synthesis inhibition. Its prescribed use, mainly in leukemia and lymphoma treatment in tandem with chemo drugs, has proven effective in achieving desired treatment outcomes. Additional consultation with medical practitioners is highly encouraged for optimal cancer-remediation efficacy. Synonyms: (2R,3S,4S,5R)-2-(2-Chloro-6-(furan-2-yl)-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol; 2-Chloro-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-6-(2-furyl)-9H-purine. Grades: ≥95%. CAS No. 1612192-00-3. Molecular formula: C14H12ClFN4O4. Mole weight: 354.72.
2-Chloro-N6-cyclopentyl 2'-deoxy-adenosine
2-Chloro-N6-cyclopentyl 2'-deoxy-adenosine, a chemical compound used in the biomedical industry to research treatments for various diseases, including cancers and viral infections such as HIV and hepatitis B, has captivated the interest of researchers worldwide. However, its therapeutic potential extends far beyond infectious diseases- studies suggest that it may serve as a potent agent for treating neurodegenerative disorders such as Parkinson's and Alzheimer's. Synonyms: (2R,3S,5R)-5-(2-Chloro-6-cyclopentylamino-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol; AAG125; (2R,3S,5R)-5-[2-chloro-6-(cyclopentylamino)purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol; 2-Chloro-N-cyclopentyl-2'-deoxyadenosine; 2-chloro-6-(cyclohexylamino)-9-(2'-deoxy-β-D-erythro-pentofuranosyl)-9H-purine. Grades: ≥95%. CAS No. 215108-39-7. Molecular formula: C15H20ClN5O3. Mole weight: 353.80.
2'-Deoxy-2'-fluoro-5-methyl-arabinocytidine
It is an anticancer agent. Synonyms: 2'-Fluoro-5-methyl-1-beta-D-arabinosylcytosine; 1-(2'-Deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-methyluracil; 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyl-; 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-imino-5-methyl-pyrimidin-2-one; 2'-fluoro-5-methylarabino-furanosylcytosine. Grades: ≥95%. CAS No. 78636-53-0. Molecular formula: C10H14FN3O4. Mole weight: 259.23.
2-Deoxy-2-fluoro-6-S-methyl-6-thio-arabino-inosine, a potent nucleoside analog, serves as an effective antiviral medication for treating hepatitis B and C among other viral infections. By suppressing viral polymerase activity, this drug effectively hinders viral replication and dispersal, thereby counteracting the progression of the targeted ailment. Synonyms: 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methylthiopurine; (2R,3R,4S,5R)-4-Fluoro-2-hydroxymethyl-5-(6-methylsulfanyl-purin-9-yl)-tetrahydro-furan-3-ol; (2R,3R,4S,5R)-4-fluoro-2-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)oxolan-3-ol; 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)-6-(methylsulfanyl)-9H-purine. Grades: ≥95%. CAS No. 109304-12-3. Molecular formula: C11H13FN4O3S. Mole weight: 300.31.
2'-Deoxy-2'-fluoro-beta-D-arabinocytidine
It is a metabolite of FIAC and an impurity of Azvudine. It is also an anticancer agent. Synonyms: 4-Amino-1-(2-deoxy-2-fluoro-D-arabinofuranosyl)-2(1H)-pyrimidinone; 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine. Grades: ≥95%. CAS No. 56632-83-8. Molecular formula: C9H12FN3O4. Mole weight: 245.21.
2'-Deoxy-5-(2-iodoethyl)uridine
2'-Deoxy-5-(2-iodoethyl)uridine, an indispensable component utilized extensively in the realm of biomedical research, assumes a pivotal position in the progress of antiviral pharmaceuticals aimed at addressing viral afflictions. Remarkably intricate in its composition, this compound exhibits unparalleled proficiency in selectively honing in on viral enzymes, effectively impeding the replication of virulent agents. Synonyms: 5-(2-Iodoethyl)-2'-deoxyuridine; 1-(4-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-(2-iodo-ethyl)-1H-pyrimidine-2,4-dione. CAS No. 90301-67-0. Molecular formula: C11H15IN2O5. Mole weight: 382.15.
2-Deoxyadenosine Monohydrate (2'-dA·H2O)
Used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents. Group: Biochemicals. Alternative Names: 2'-dA·H2O; 9-(2-Deoxy-b-D-ribofuranosyl)adenine; 2'-Deoxy-D-adenosine; (2R, 3S, 5R) -5- (6-Amino-9H-purin-9-yl) -2- (hydroxymethyl) tetrahydrofuran-3-ol; 9-(2-Deoxy- β -D-erythro-pentofuranosyl) adenine; 9-(2-Deoxy- β-D-erythro-pentofuranosyl)-9H-purin-6-amine; Adenine Deoxyribonucleoside; Adenine Deoxyribose; Adenyldeoxyriboside; Deoxyadenosine; Desoxyadenosine; NSC 141848; NSC 143510; NSC 83258; dA; 1-(6-Amino-9H-purin-9-yl)-1,2-dideoxy- β-D-ribofuranose; 2-Deoxyadenine-9- β-D-erythro-pento-furanoside. Grades: Molecular Biology Grade. CAS No. 16373-93-6. Pack Sizes: 5g, 10g, 25g, 50g. Molecular Formula: C10H13N5O3·H2O, Molecular Weight: 269.24. US Biological Life Sciences.
Worldwide
2'-Deoxyguanosine-5'-carboxylic acid
2'-Deoxyguanosine-5'-carboxylic acid, an indispensable compound in the biomedical sector, exhibits profound significance in the realm of DNA synthesis and repair. Its pivotal role renders it a commendable instrument in unraveling the intricacies of DNA damage and repair mechanisms. Furthermore, this compound contributes to the advancement of therapeutic medications, specifically targeting afflictions like cancer and viral infections. The multifaceted nature of its applications bestows upon it an irreplaceable value, enhancing the landscape of biomedical research. Synonyms: 1-(2-amino-1,?6-dihydro-6-oxo-9H-purin-9-yl)?-1,?2-dideoxy-b-D-erythro-pentofuranuronic acid; (2S,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-3-hydroxy-tetrahydro-furan-2-carboxylic acid. CAS No. 82534-56-3. Molecular formula: C10H11N5O5. Mole weight: 281.23.
2'-Deoxy-N2,N2-diethylguanosine
2'-Deoxy-N2,N2-diethylguanosine is a nucleoside analog that has performed well in studies against specific malignancies. It exerts therapeutic action by undermining DNA replication, ultimately leading to the demise of tumor cells. Exploiting the modification of guanine nucleotides, this compound exhibits auspicious outcomes in preclinical diverse malignant neoplasms investigations. Synonyms: Guanosine, 2'-deoxy-N,N-diethyl-; N2,N2-diethyl-2'-deoxyguanosine; 2-Diethylamino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one. Grades: ≥95%. CAS No. 236389-19-8. Molecular formula: C14H21N5O4. Mole weight: 323.35.
2'-Deoxy-N4,N4-dimethylcytidine
2'-Deoxy-N4,N4-dimethylcytidine is a biomedical compound widely used in the reserch of viral diseases, such as hepatitis and HIV. It functions by inhibiting viral replication and promoting immune response, leading to the suppression of viral load. Synonyms: N,N-Dimethyl-2'-deoxycytidine; 2'-Deoxy-N4-dimethylcytidine; N4,N4-dimethyl-2'-deoxycytidine; 4-Dimethylamino-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one; 1-(2-Deoxy-β-D-ribofuranosyl)-4-dimethylamino-2(1H)-pyrimidinone. Grades: ≥95%. CAS No. 53213-03-9. Molecular formula: C11H17N3O4. Mole weight: 255.27.
2-Diethoxymethyladenosine
2-Diethoxymethyladenosine is a biomedical product acting as an adenosine receptor agonist, exhibiting potential anti-inflammatory and anti-cancer properties. This compound can be employed in drug development research targeting conditions such as cardiovascular diseases, immune disorders and certain types of cancer. Synonyms: (2R,3R,4S,5R)-2-(6-Amino-2-diethoxymethyl-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol. Grades: ≥95%. CAS No. 79957-15-6. Molecular formula: C15H23N5O6. Mole weight: 369.37.
2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine
2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine is a remarkable and transformative compound research and development, manifesting its remarkable potential in research of an array of incessant and pernicious viral infections. As a meticulously tailored nucleoside analog, this compound exerts its magnificent influence by diligently thwarting the relentless propagation of notorious entities such as herpes simplex virus (HSV) and human immunodeficiency virus (HIV). Synonyms: 2-Fluoro-O6-(p-nitrophenylethyl)-9-b-D-ribofuranosyl)purine; 2-Fluoro-9-(beta-D-ribofuranosyl)-6-[2-(4-nitrophenyl)ethoxy]-9H-purine; (2R,3R,4S,5R)-2-{2-Fluoro-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol; 2-fluoro-O6-[2-(4-nitrophenyl)ethyl]inosine. Grades: ≥95%. CAS No. 171284-49-4. Molecular formula: C18H18FN5O7. Mole weight: 435.36.
2-Iodo-2'-deoxyadenosine is a biomedical product used in the treatment of certain cancers. It functions by inhibiting DNA synthesis, leading to cellular death in cancer cells. It is specifically effective in treating hematological malignancies, such as leukemia and lymphoma. Synonyms: 2'-Dexoy-2-iodo-adenosine; Adenosine, 2'-deoxy-2-iodo-; (2R,3S,5R)-5-(6-Amino-2-iodo-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol; 2-iodo-9-(2-deoxy-β-D-ribofuranosyl)adenine; 2-iodo-deoxyadenosine. Grades: ≥95%. CAS No. 118706-49-3. Molecular formula: C10H12IN5O3. Mole weight: 377.14.
2'-O-Methyl-2-thiouridine
2'-O-Methyl-2-thiouridine is a valuable compound widely used in biomedicine. It acts as an RNA modification tool, incorporating into RNA molecules during synthesis. This powerful molecule exhibits antiviral activity against various viral infections, making it a potential therapeutic option for treating RNA virus-associated diseases. Its unique properties and versatility make it an essential tool for studying RNA biology and developing antiviral therapies. Synonyms: 2-thio-2'-O-methyluridine; Uridine, 2'-O-methyl-2-thio-; 1-(2-O-Methyl-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,3-dihydro-1-(2-O-methyl-β-D-ribofuranosyl)-2-thioxo-; 1-((2R,3R,4R,5R)-4-Hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one. Grades: ≥95%. CAS No. 113886-72-9. Molecular formula: C10H14N2O5S. Mole weight: 274.29.
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol is an incredibly potent antiviral compound, employed to combat both hepatitis B and HIV infections. Acting through the inhibition of the reverse transcriptase enzyme, it can reduce viral load and limit replication within the patient's bloodstream. Synonyms: 5-(2-Amino-6-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-4-methyl-tetrahydro-furan-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyl-tetrahydrofuran-3-ol. CAS No. 881881-89-6. Molecular formula: C11H13ClFN5O3. Mole weight: 317.70.
2-Tetrahydrofurfurylamine
2-Tetrahydrofurfurylamine. Group: Biochemicals. Alternative Names: 2- (Aminomethyl) tetrahydrofuran; Tetrahydro-2-furanmethanamine. Grades: Highly Purified. CAS No. 4795-29-3. Pack Sizes: 100g, 250g, 500g, 1kg. Molecular Formula: C5H11NO. US Biological Life Sciences.
Worldwide
2'-Thioadenosine
2'-Thioadenosine is used as a synthetic intermediate for making a potent and selective erbB-1 (a.k.a. epidermal growth factor receptor) and erbB-2 (a.k.a. neu/her2 growth factor receptor) tyrosine kinase inhibitor. Synonyms: 2'-Thioadenosine; 136904-69-3; CHEMBL14326; (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-sulfanyloxolan-3-ol; thioadenosine; SCHEMBL2699533; DTXSID20435431; 60239-18-1 (non-salt); BDBM50057300; PD138045; J-006937; (2R,3R,4R,5R)-5-(6-Amino-purin-9-yl)-2-hydroxymethyl-4-mercapto-tetrahydro-furan-3-ol; (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-mercaptotetrahydrofuran-3-ol. CAS No. 136904-69-3. Molecular formula: C10H13N5O3S. Mole weight: 283.31.
compound: 3',5'-Bis(O-t-butyldimethylsilyl)-4'-C-hydroxymethyl thymidine is an indispensable harbinger in the realm of biomedicine, resolutely illuminating the nuances of DNA synthesis and transcription. Its utility lies in the realm of synthesizing modified nucleoside analogs, thereby unraveling the intricate tapestry of DNA replication and repair mechanisms. Synonyms: 1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-5-hydroxymethyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione; 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 3'-O,5'-O-Bis(tert-butyldimethylsilyl)-4'-(hydroxymethyl)thymidine. Grades: ≥95%. CAS No. 179178-45-1. Molecular formula: C23H44N2O6Si2. Mole weight: 500.78.
3'-Amino-3'-deoxy-5-methyluridine
3'-Amino-3'-deoxy-5-methyluridine, a pivotal compound widely utilized in the biomedical industry, assumes utmost significance in the investigation of antiviral pharmaceuticals and viral-induced ailments. Synonyms: Uridine, 3'-amino-3'-deoxy-5-methyl-; 1-(3-Amino-3-deoxy-beta-D-ribofuranosyl)thymine; 1-((2R,3R,4S,5S)-4-Amino-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-((2R,3R,4S,5S)-4-Amino-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 108630-07-5. Molecular formula: C10H15N3O5. Mole weight: 257.24.
3'-Azido-3'-deoxy-5-methyuridine
2α-Hydroxy Zidovudine is a metabolite of Zidovudine, a potent and selective HIV-1 replication inhibitor. Synonyms: 2α-Hydroxy Zidovudine; 1-(3-Azido-3-deoxy-beta-D-ribofuranosyl)thymine; 1-((2R,3R,4S,5S)-4-Azido-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 215176-58-2. Molecular formula: C10H13N5O5. Mole weight: 283.24.
3'-b-C-Methyluridine
3'-b-C-Methyluridine, a compound highly regarded in the biomedical sector, showcases immense significance due to its broad applications. It manifests exceptional potential in combating various diseases, including cancer, viral infections, and autoimmune disorders. Notably, it possesses pharmacological attributes as an antineoplastic agent, effectively hindering viral replication and orchestrating the modulation of immune responses. The utilization of 3'-b-C-Methyluridine in drug development and comprehensive biomedicine investigations exhibits considerable promise, highlighting its paramount importance in scientific research. Synonyms: 3'-beta-C-Methyluridine; 1-(3-C-methyl-β-D-ribofuranosyl)uracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-4-methyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione; 3'-C-methyluridine; 3'-methyluridine. Grades: ≥95%. CAS No. 80541-15-7. Molecular formula: C10H14N2O6. Mole weight: 258.23.
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