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| Product | Description | |
|---|---|---|
| 1,2,3,4-Tetrahydroquinoline-5-carboxylic acid | Heterocyclic Organic Compound. Alternative Names: 1,2,3,4-tetrahydroquinoline-5-carboxylic acid, 114527-54-7, 5-Quinolinecarboxylicacid, 1,2,3,4-tetrahydro-, ACMC-1BPEV, SureCN5227788, AGN-PC-00OE98, AC1Q72Q5, CTK0H3204, MolPort-002-471-777, AKOS008083509, AG-D-34855, MCULE-6324304358, AK122253, KB-216243, 1,2,3,4-Tetrahydro-5-quinolinecarboxylicacid, EN300-26274, 5-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-, T5706012, I14-15642. CAS No. 114527-54-7. Molecular formula: C10H11NO2. Mole weight: 177.199840 [g/mol]. Purity: 0.96. IUPACName: 1,2,3,4-tetrahydroquinoline-5-carboxylic acid. Catalog: ACM114527547. |  |
| 1-Boc-1,2,3,4-tetrahydroquinoline-2-carboxylic acid | 1-Boc-1,2,3,4-tetrahydroquinoline-2-carboxylic acid. Group: Biochemicals. Alternative Names: 1-Boc-3,4-dihydro-2H-quinoline-2-carboxylic acid; 3,4-Dihydro-2H-quinoline-1,2-dicarboxylic acid 1-tert-butyl ester. Grades: Highly Purified. CAS No. 123811-87-0. Pack Sizes: 250mg, 500mg, 1g, 2g. US Biological Life Sciences. |  Worldwide |
| 1-Methanesulfonyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid | 1-Methanesulfonyl-1,2,3,4-tetrahydro-quinoline-6-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 852916-95-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H13NO4S, Molecular Weight: 255.29. US Biological Life Sciences. | Worldwide |
| 6-Hydroxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid methyl ester | Heterocyclic Organic Compound. Alternative Names: 6-Hydroxy-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid methyl ester. CAS No. 1219397-09-7. Molecular formula: C11H13NO3. Mole weight: 207.22582;g/mol. Purity: 0.96. IUPACName: methyl6-hydroxy-1,2,3,4-tetrahydroquinoline-2-carboxylate. Canonical SMILES: COC(=O)C1CCC2=C(N1)C=CC(=C2)O. Catalog: ACM1219397097. | |
| 11-Desethyl Irinotecan | 11-Desethyl Irinotecan is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500). Group: Biochemicals. Alternative Names: (4S)-4-Ethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-9-yl Ester [1,4'-Bipiperidine]-1'-carboxylic Acid; 1H-Pyrano[3', 4':6, 7]indolizino[1, 2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; 10- [4- (1-Piperidino) -1-piperidinocarbonyloxy] camptothecin. Grades: Highly Purified. CAS No. 103816-16-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 11-Desethyl Irinotecan-d10 | 11-Desethyl Irinotecan-d10. Group: Biochemicals. Alternative Names: (4S)-4-Ethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-9-yl Ester [1,4'-Bipiperidine]-1'-carboxylic Acid-d10; 1H-Pyrano[3', 4':6, 7]indolizino[1, 2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.-d10; 10- [4- (1-Piperidino) -1-piperidinocarbonyloxy] camptothecin-d10. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C31H24D10N4O6, Molecular Weight: 568.69. US Biological Life Sciences. | Worldwide |
| 12-Hydroxy irinotecan | 12-Hydroxy irinotecan. Group: Biochemicals. Alternative Names: [1,4'-Bipiperidine]-1'-carboxylic acid (4S)-4,11-diethyl-3,4,12,14-tetrahydro- 4, 12-dihydroxy-3, 14-dioxo-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-9-yl ester; (4S) -4, 11-Diethyl-4, 12-dihydroxy-9-[ (4-piperidinopiperidino) carbonyloxy]-1H-pyrano[3', 4': 6, 7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H) -dione; RPR 112524. Grades: Highly Purified. CAS No. 185336-12-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C33H38N4O7. US Biological Life Sciences. | Worldwide |
| 3-Quinolinecarboxylicacid,1,2,5,6,7,8-hexahydro-2,5-dioxo- | Heterocyclic Organic Compound. Alternative Names: 106551-76-2, 2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid, 2,5-dioxo-1,6,7,8-tetrahydroquinoline-3-carboxylic acid, 3-Quinolinecarboxylicacid, 1,2,5,6,7,8-hexahydro-2,5-dioxo-, AC1Q73SK, SureCN9802503, ACMC-1C677, CHEMBL314235, CTK0H2647, MolPort-003-356-128, MolPort-005-973-494, BB_SC-4827, BBL008452, SBB082674, SF 130, STK508786, AKOS001386613, AG-D-21058, MCULE-6585944629, AK-55837. CAS No. 106551-76-2. Molecular formula: C10H9NO4. Mole weight: 207.19. Purity: 0.96. IUPACName: 2,5-dioxo-1,6,7,8-tetrahydroquinoline-3-carboxylic acid. Canonical SMILES: C1CC2=C(C=C(C(=O)N2)C(=O)O)C(=O)C1. Catalog: ACM106551762. | |
| 6-Chloro-2-hydroxy-quinoline-4-carboxylic acid | Heterocyclic Organic Compound. Alternative Names: Pyrindamycin B, duocarmycin C1, Antibiotic DC 89A1, C26H26ClN3O8, DC89-A1, DC 89-A1, BRN 5689373, CID133973, LS-21000, LS-139683, 1H-Pyrrolo(3,2-f)quinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester, 113189-05-2, 118292-35-6, 1H-Pyrrolo(3,2-f)quinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester. CAS No. 118292-35-6. Molecular formula: C10H6ClNO3. Mole weight: 223.61. Purity: 0.96. IUPACName: methyl (2R,8S)-8-chloro-4-hydroxy-7-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-3,7,8,9-tetrahydro-2H-pyrrolo[3,2-f]quinoline-2-carboxylate. Canonical SMILES: C1=CC2=C(C=C1Cl)C(=CC(=O)N2)C(=O)O. Catalog: ACM118292356. | |
| Clopyralid 95% tech | Heterocyclic Organic Compound. Alternative Names: Hexadiindisaeure; Butadiindicarbonsaeure; Diacetylen-dicarbonsaeure; 2,4-Hexadiynedioic acid; Diacetylenedicarboxylic acid; hexadiynedioic acid; hexa-2,4-diyne-1,6-dioic acid. CAS No. 1072-17-6. Molecular formula: C13H12INO2. Mole weight: 341.14435;g/mol. Purity: 0.96. IUPACName: 6-iodo-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylicacid. Canonical SMILES: C1C=CC2C1C(NC3=C2C=CC=C3I)C(=O)O. Catalog: ACM1072176. | |
| Irinotecan | Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. It is used for the treatment of colon and rectum cancers. It binds to topoisomerase I-DNA complex, preventing religation of the DNA strand and leading to double-strand DNA breakage and cell death. Uses: Topoisomerase i inhibitors. Synonyms: Irinophore C; Irinotecan lactone; Irinotecan mylan; Onivyde; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; (S)-[1,4'-Bipiperidine]-1'-carboxylic Acid 4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester; Camptosar; Irinotecanum; CPT-11; CPT 11; CPT11; (+)-Irinotecan. Grades: ≥98%. CAS No. 97682-44-5. Molecular formula: C33H38N4O6. Mole weight: 586.68. |  |
| (+)-ITD-1 | (+)-ITD-1 is the (+)-enantiomer of ITD 1 that is more active. ITD-1 is a selective inhibitor of TGFβ/Smad signaling (IC50 values 0.46 μM and 6.90 μM for (+)-ITD 1 and (-)-ITD 1, respectively for TGF-β inhibition) that clears the type II TGFβ receptor from the cell surface. ITD 1 promotes the differentiation of cardiomyocytes and cardiogenesis in murine embryonic stem cell (mESCs). Synonyms: ITD-1; 1099644-42-4; ITD 1; ITD1; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate; (+)-ITD 1; 1409968-46-2; 4-[1,1'-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester; Ethyl 4-([1,1'-biphenyl]-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate; ethyl 4-(biphenyl-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate;6-{(1R)-1-[8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H) -one; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate. Grades: 99%. CAS No. 1409968-46-2. Molecular formula: C27H29NO3. Mole weight: 415.52. | |
| L-689,560 | L-689,560 is a potent antagonist at the glycine-NMDA receptor site. It is a bioactive chemical. Synonyms: L689560; L 689560; L-689560; trans-(±)-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; rel-(2R,4S)-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; (2R,4S)-rel-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; trans-5,7-Dichloro-1,2,3,4-tetrahydro-4-[[(phenylamino)carbonyl]amino]-2-quinolinecarboxylic Acid; trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline; (2S,4R)-5,7-dichloro-4-[(phenylcarbamoyl)amino]-1,2,3,4-tetrahydroquinoline-2-carboxylic acid. Grades: ≥99% by HPLC. CAS No. 139051-78-8. Molecular formula: C17H15Cl2N3O3. Mole weight: 380.23. | |
| Nadifloxacin isomer 3 | An impurity of Nadifloxacin, which is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Synonyms: 9-fluoro-5-methyl-1-oxo-8-(4-oxopyridin-1(4H)-yl)-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid. Grades: > 95%. Molecular formula: C19H15FN2O4. Mole weight: 354.34. | |
| Nadifloxacin isomer 4 | An impurity of Nadifloxacin, which is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Synonyms: 8-amino-9-fluoro-5-methyl-1,7-dioxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid. Grades: > 95%. Molecular formula: C15H15FN2O4. Mole weight: 306.3. | |
| 21s-Argatroban | Heterocyclic Organic Compound. Alternative Names: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[[(3S)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl]sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. CAS No. 121785-72-6. Molecular formula: C23H36N6O5S. Mole weight: 508.63. Purity: 0.96. IUPACName: (2R,4R)-1-[5-(diaminomethylideneamino)-2-[[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid. Canonical SMILES: CC1CCN (C (C1)C (=O)O)C (=O)C (CCCN=C (N)N)NS (=O) (=O)C2=CC=CC3=C2NCC (C3)C. Catalog: ACM121785726. | |
| BMS-593214 | BMS-593214 is an active-site, direct FVIIa inhibitor. It displayed direct, competitive inhibition of human FVIIa in the hydrolysis of a tripeptide substrate with Ki of 5 nM. Synonyms: BMS593214; BMS 593214; 2'-(2-Carbamimidoyl-5,6a,7,11b-tetrahydro-6H-indeno[2,1-c]quinolin-6-yl)-5'-hydroxy-4'-methoxy-biphenyl-4-carboxylic acid. Grades: >98%. CAS No. 1004551-40-9. Molecular formula: C31H27N3O4. Mole weight: 505.56. | |
| Irinotecan hydrochloride | Irinotecan hydrochloride. Group: Biochemicals. Alternative Names: [1,4'-Bipiperidine]-1'-carboxylic Acid (4S)-4,11-Diethyl-3,4,12,14- tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3', 4':6, 7]indolizino[1, 2-b]quinolin-9-yl Ester Hydrochloride Trihydrate; Campto; CPT11; Irinotecan hydrochloride trihydrate. Grades: Highly Purified. CAS No. 100286-90-6,136572-09-3. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C33H38N4O6·HCl. US Biological Life Sciences. | Worldwide |
| Irinotecan, Hydrochloride Salt, Trihydrate ([1,4-Bipiperidine]-1-carboxylic Acid (S)-4, 11-diethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3, 4, 6, 7]indolizino[1, 2-b]quinolin-9-yl Ester, HCl Trihydrate) | Irinotecan (CPT-11) is a topoisomerase I inhibitor. It is a semisynthetic analog of the natural alkaloid camptothecin and has an active metabolite SN-38 (7-Ethyl-10-hydroxycamptothecin). During the S phase of the cell cycle, camptothecins selectively bind to and stabilize topoisomerase I-DNA complexes, inhibiting religation, causing the accumulation of topoisomerase I-mediated single-strand DNA breaks in the DNA, and producing irreversible double-strand DNA breaks that lead to cell death. Group: Biochemicals. Grades: Highly Purified. CAS No. 136572-09-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Irinotecan, Hydrochloride, Trihydrate ([1,4-Bipiperidine]-1-carboxylic Acid (S)-4, 11-diethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3, 4, 6, 7]indolizino[1, 2-b]quinolin-9-yl Ester, HCl Trihydrate) | A DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: [1,4-Bipiperidine]-1-carboxylic acid (S)-4, 11-diethyl-3, 4, 12, 14-tetrahydro-4-hydroxy-3, 14-dioxo-1H-pyrano[3, 4, 6, 7]indolizino[1, 2-b]quinolin-9-yl ester, Hcl Trihydrate. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Simmitecan Hydrochloride | This active molecular is a topoisomerase I inhibitor originated by ShangHai HaiHe Pharmaceutical. Simmitecan is also a promising water-soluble prodrug of chimmitecan using for the treatment of Solid tumours. In Aug 2016, ShangHai HaiHe Pharmaceutical planed a phase I study in Solid tumours (Monotherapy, Combination therapy) or Colorectal cancer (Combination therapy) in China. Uses: Solid tumours. Synonyms: [1,4'-Bipiperidine]-1'-carboxylic acid, (4S)-4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-10-(2-propen-1-yl)-1H-pyrano[3',4':6,7]indolizino[1,2- b]quinolin-9-yl ester, hydrochloride (1:1);951290-31-6 (Simmitecan). Grades: 98%. CAS No. 1247847-78-4. Molecular formula: C34H38N4O6.HCl. Mole weight: 635.16. | |
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