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Tetrazine-Ph-PEG5-NHS ester Tetrazine-Ph-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Tetrazine-Ph-PEG5-NHS ester is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1682653-80-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-130551. MedChemExpress MCE
1,4-Dihydro-[1,2,4,5]tetrazine-3,6-dicarboxylic acid,disodium salt 1,4-Dihydro-[1,2,4,5]tetrazine-3,6-dicarboxylic acid,disodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-DIHYDRO-[1,2,4,5]TETRAZINE-3,6-DICARBOXYLIC ACID, DISODIUM SALT. Product Category: Heterocyclic Organic Compound. CAS No. 96898-32-7. Molecular formula: C4H2N4Na2O4. Mole weight: 216.06. Purity: 0.96. IUPACName: disodium 1,4-dihydro-1,2,4,5-tetrazine-3,6-dicarboxylate. Product ID: ACM96898327. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
3,6-Bis(4-Pyridyl)-S-Tetrazine 3,6-Bis(4-Pyridyl)-S-Tetrazine. Group: Nitrogen-containing mof ligand-binary nitrogen-containing mof ligand. CAS No. 57654-36-1. Product ID: 3,6-dipyridin-4-yl-1,2,4,5-tetrazine. Molecular formula: 236.23g/mol. Mole weight: C12H8N6. InChI=1S/C12H8N6/c1-5-13-6-2-9 (1)11-15-17-12 (18-16-11)10-3-7-14-8-4-10/h1-8H. MQSMIIJCRWDMDL-UHFFFAOYSA-N. Alfa Chemistry Materials 7
3,6-Di(2-pyridyl)-1,2,4,5-tetrazine 3,6-Di(2-pyridyl)-1,2,4,5-tetrazine. Group: Metal organic frameworks (mofs). Alternative Names: 3,6-Bis(2-pyridyl)-1,2,4,5-tetrazine. CAS No. 1671-87-0. Product ID: 3,6-dipyridin-2-yl-1,2,4,5-tetrazine. Molecular formula: 236.24. Mole weight: C12H8N6. C1=CC=NC (=C1)C2=NN=C (N=N2)C3=CC=CC=N3. InChI=1S/C12H8N6/c1-3-7-13-9 (5-1)11-15-17-12 (18-16-11)10-6-2-4-8-14-10/h1-8H. JFBIRMIEJBPDTQ-UHFFFAOYSA-N. >98.0%(HPLC). Alfa Chemistry Materials 4
3,6-Di-4-pyridyl-1,2,4,5-tetrazine 3,6-Di-4-pyridyl-1,2,4,5-tetrazine. Group: Metal organic frameworks (mofs). Alternative Names: 3,6-Di(4-pyridyl)-1,2,4,5-tetrazine, 57654-36-1, AC1NLEVE, 3,6-dipyridin-4-yl-1,2,4,5-tetrazine, SureCN1898780, Oprea1_022240, ACMC-1B023, CTK1G8149, ANW-32766, ZINC02582077, AG-G-03628, 3,6-Bis(4-pyridyl)-1,2,4,5-tetrazine, D3211, 3,6-DI-4-PYRIDYL-1,2,4,5-TETRAZINE, 3,6-DI-PYRIDIN-4-YL-1,2,4,5-TETRAZINE, 3,6-DI-4-PYRIDYL-1,2,4,5-TETRAZINE; 3,6-BIS(4-PYRIDYL)-1,2,4,5-TETRAZINE; 2,5-DI-(4-PYRIDYL)-S-TETRAZINE. CAS No. 57654-36-1. Product ID: 3,6-dipyridin-4-yl-1,2,4,5-tetrazine. Molecular formula: 236.23. Mole weight: C12< / sub>H8< / sub>N6< / sub>. C1=CN=CC=C1C2=NN=C(N=N2)C3=CC=NC=C3. MQSMIIJCRWDMDL-UHFFFAOYSA-N. 96%. Alfa Chemistry Materials 7
3,6-Diamino-1,2-dihydro-1,2,4,5-tetrazine Hydrochloride 3,6-Diamino-1,2-dihydro-1,2,4,5-tetrazine Hydrochloride. Group: Biochemicals. Alternative Names: 1,2-Dihydro-1,2,4,5-tetrazine-3,6-diamine Hydrochloride. Grades: Highly Purified. CAS No. 133488-87-6. Pack Sizes: 5mg. Molecular Formula: C2H7ClN6, Molecular Weight: 114.11. US Biological Life Sciences. USBiological 3
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3,6-di(pyridin-3-yl)-1,2,4,5-tetrazine 3,6-di(pyridin-3-yl)-1,2,4,5-tetrazine. Group: Customizable mof linkers. CAS No. 107599-30-4. Product ID: 3,6-dipyridin-3-yl-1,2,4,5-tetrazine. Molecular formula: 236.23g/mol. Mole weight: C12H8N6. InChI=1S/C12H8N6/c1-3-9 (7-13-5-1)11-15-17-12 (18-16-11)10-4-2-6-14-8-10/h1-8H. OLXAHCQKLVGQOG-UHFFFAOYSA-N. Alfa Chemistry Materials 7
5-FAM-PEG4-TETRAZINE Also known as 5-carboxyfluorescein-PEG4-Tetrazine. A pegylated FAM dye with enhanced water solubility and containing a tetrazine moiety for Tetrazine-TCO ligation. Uses: For industrial and laboratory use. Product Category: Fluorescein Dyes. Appearance: Red solid. Molecular formula: C41H40N6O11. Mole weight: 792.79 g/mol. Purity: 0.95. Product ID: DYE-FLU-0064. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
BDP TR methyltetrazine BDP TR methyltetrazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[4-(2,2-Difluoro-12-thiophen-2-yl-1,3-diaza-2-boranuidatricyclo[7.3.0.03,7]dodeca-5,7,9,11-tetraen-4-yl)phenoxy]-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]acetamide. Product Category: BODIPY Fluorophores. CAS No. 2183473-54-1. Molecular formula: C31H24BF2N7O2S. Mole weight: 607.5. Purity: 0.98. IUPACName: 2-[4-(2,2-difluoro-12-thiophen-2-yl-1,3-diaza-2-boranuidatricyclo[7.3.0.03,7]dodeca-5,7,9,11-tetraen-4-yl)phenoxy]-N-[[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenyl]methyl]acetamide. Canonical SMILES: [B-]1(N2C(C=CC2=CC3=CC=C(N31)C4=CC=CS4)C5=CC=C(C=C5)OCC(=O)NCC6=CC=C(C=C6)C7=NN=C(N=N7)C)(F)F. Product ID: ACM2183473541-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Janelia Fluor® 646, Tetrazine Janelia Fluor 646, Tetrazine (JF646, Tetrazine) a red fluorescent dye that contains a tetrazine group. JF646, Tetrazine can be used in cellular imaging [1]. Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. Janelia Fluor 646, Tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: JF646, Tetrazine. CAS No. 2042192-00-5. Pack Sizes: 200 μg; 500 μg; 1 mg. Product ID: HY-138659. MedChemExpress MCE
Methyltetrazine-Amine Methyltetrazine-Amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345955-28-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135140. MedChemExpress MCE
Methyltetrazine-amine hydrochloride Methyltetrazine-Amine, a tetrazine compound, is used for the site-specific dual functionalization of the resulting bioconjugates [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1596117-29-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135140A. MedChemExpress MCE
Methyltetrazine-PEG4-maleimide Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802908-02-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141278. MedChemExpress MCE
Sulfo-Cy3-Methyltetrazine Sulfo-Cy3-Methyltetrazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Methyl-Tetrazine-Sulfo-Cy3. Product Category: Cyanine Fluorophores. CAS No. 1801924-47-9. Molecular formula: C42H49N7O10S3. Mole weight: 908.1. Purity: 0.95. Product ID: ACM1801924479-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Sulfo-Cy3-Tetrazine Sulfo-Cy3-Tetrazine. Uses: Designed for use in research and industrial production. Product Category: Cyanine Fluorophores. CAS No. 2055138-86-6. Molecular formula: C41H47N7O10S3. Mole weight: 894.1. Purity: 0.9. Product ID: ACM2055138866-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
Sulfo-Cy5-tetrazine Sulfo Cy5-tetrazine is a tetrazine-coupled Cy5 (HY-D0821) derivative dye with fluorescence properties similar to CY5 (Ex/Em=633/647 nm). Sulfo-Cy5-tetrazine is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1801695-57-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1482. MedChemExpress MCE
Sulfo-Cy5-Tetrazine Sulfo-Cy5-Tetrazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cy5tetrazine. Product Category: Cyanine Fluorophores. CAS No. 1801695-57-7. Molecular formula: C43H49N7O10S3. Mole weight: 920.1. Purity: 0.9. IUPACName: 2-[(1E,3E,5E)-5-[3,3-dimethyl-1-[6-oxo-6-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methylamino]hexyl]-5-sulfoindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethyl-1-(3-sulfopropyl)indol-1-ium-5-sulfonate. Canonical SMILES: CC1(C2=C(C=CC(=C2)S(=O)(=O)[O-])[N+](=C1/C=C/C=C/C=C/3\C(C4=C(N3CCCCCC(=O)NCC5=CC=C(C=C5)C6=NN=CN=N6)C=CC(=C4)S(=O)(=O)O)(C)C)CCCS(=O)(=O)O)C. Product ID: ACM1801695577-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
1,2,3-Triaminoguandine Hydrochloride 1,2,3-Triaminoguandine is used to prepare 3-arylamino-6-benzylamino-1,2,4,5-tetrazines with antimalarial activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 5329-29-3. Pack Sizes: 250mg, 1g. Molecular Formula: CH9ClN6, Molecular Weight: 140.58. US Biological Life Sciences. USBiological 9
Worldwide
Clofentezine Clofentezine. Group: Biochemicals. Alternative Names: NC 21314; 3,6-Bis(2-chlorophenyl)-1,2,4,5-tetrazine; Acaristop; Apollo; Apollo (pesticide); Apollo 50W; Apollo SOSC; Bisclofentezin; Bisclofentezine; 3,6-Bis(2-chlorophenyl)-1,2,4,5-tetrazine. Grades: Highly Purified. CAS No. 74115-24-5. Pack Sizes: 1g. Molecular Formula: C14H8Cl2N4, Molecular Weight: 303.149999999999. US Biological Life Sciences. USBiological 3
Worldwide
Clofentezine Clofentezine is an active substance of plant protection product used as pesticide, acaricide. It belongs to the chemical family of quinoxalines. It is used in agriculture for the protection of ornamentals, food and non-food crops in the field. It has sublethal effects on life-table parameters of Tetranychus urticae Koch females. Uses: Clofentezine is used as a pesticide, acaricide. it is used in agriculture for the protection of ornamentals, food and non-food crops in the field. Synonyms: NC 21314; 3, 6-Bis(2-chlorophenyl)-1, 2, 4, 5-tetrazine; Acaristop; Apollo; Bisclofentezin. Grades: 98%. CAS No. 74115-24-5. Molecular formula: C14H8Cl2N4. Mole weight: 303.15. BOC Sciences 9
TCO-NHS ester TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191901-33-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141165. MedChemExpress MCE
TCO-PEG3-FITC A FITC probe functionalized with a TCO moiety for tetrazine-TCO ligation and a PEG3 spacer. Uses: For industrial and laboratory use. Product Category: Other Fluorescent Dyes. Appearance: Orange solid. Molecular formula: C38H43N3O10S. Mole weight: 733.83 g/mol. Purity: 0.95. Product ID: DYE-FLU-0102. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
TCO-PEG4-NHS ester TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1621096-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141167A. MedChemExpress MCE
Temozolomide Imidazotetrazine alkylating agent. An antineoplastic. A cell-permeable, orally bioavailable, blood-brain barrier-permeant MTIC [5-(3-methyltriazen-1-yl-)-imidazole-4-carboxamide] prodrug whose in vivo DNA alkylating activity is employed in anticancer therapy. MGMT (O6-methylguanine DNA methyl transferase) repairs TMZ-damaged DNA lesion by covalently transferring O6-methylation on guanine residues to a cysteine residue on the MGMT, forming the basis of TMZ-resistance in cancer treatment. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, Methazolastone, M&B 39831, Temodal, Temodar; CCRG 81045, TMZ; NSC 362856. Grades: Highly Purified. CAS No. 85622-93-1. Pack Sizes: 10mg, 25mg, 100mg. US Biological Life Sciences. USBiological 1
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Temozolomide Acid A metabolite of Temozolomide as antitumor agent. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic Acid. Grades: Highly Purified. CAS No. 113942-30-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 3
Worldwide
Temozolomide Acid Temozolomide acid is an active metabolite of temozolomide(T017775) with anticancer activity in vitro. Temozolomide is an alkylating agent used as a treatment of some brain cancer, a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.In Apr 2016, Stanford University and Merck suspended enrolment in a phase II trial for Acute myeloid leukaemia (Combination therapy, Newly diagnosed, Second-line therapy or greater) in USA. In 14 Jul 2016, Medivation planed a phase II trial for Endometrial cancer in USA (NCT02836028) After two days, M.D. Anderson Cancer Center completed a phase II trial in Malignant melanoma (Late-stage disease, Neoadjuvant therapy, Monotherapy, Combination therapy) in USA. Uses: As an antitumor agent. Synonyms: 3,4-Dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic Acid; 3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxylic Acid; Temozolomide-8-carboxylic Acid; TMZA. Grades: 98%. CAS No. 113942-30-6. Molecular formula: C6H5N5O3. Mole weight: 195.14. BOC Sciences 9
Temozolomide Cyano Impurity One impurity of Temozolomide, which is an imidazotetrazine derivative and has been found to be a DNA methylating agent and could be used as an antineoplastic. Synonyms: 8-Descarboxamido-8-cyano Temozolomide; 3,4-Dihydro-3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carbonitrile; Cyanotemozolomide; 3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carbonitrile. Grades: > 95%. CAS No. 114601-31-9. Molecular formula: C6H4N6O. Mole weight: 176.14. BOC Sciences 8
Clofentezine Metabolite 2 Synonyms: Clofentezine Metabolite 2; 107573-62-6; 4-chloro-3-[6-(2-chlorophenyl)-1,2,4,5-tetrazin-3-yl]phenol; AKOS037652860; ES-2643. Grades: > 95%. CAS No. 107573-62-6. Molecular formula: C14H8Cl2N4O. Mole weight: 319.15. BOC Sciences 7
MOF&(4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine HCL MOF&(4-(1,2,4,5-tetrazin-3-yl)phenyl)methanamine HCL. Group: Organic-linker blocks- other linker blocks. Product ID: [4-(1,2,4,5-tetrazin-3-yl)phenyl]methanamine. Molecular formula: 187.20g/mol. Mole weight: C9H9N5. InChI=1S/C9H9N5/c10-5-7-1-3-8 (4-2-7)9-13-11-6-12-14-9/h1-4, 6H, 5, 10H2. JGCOJRPYFRRONJ-UHFFFAOYSA-N. Alfa Chemistry Materials 7
MOF&Benzenemethanamine, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)- MOF&Benzenemethanamine, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)-. Group: Organic-linker blocks- other linker blocks. Alfa Chemistry Materials 7
NEO 212 NEO 212 is a novel DNA alkylating agent that causes DNA damage and cancer cell apoptosis. It has the potent activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo (IC50 values 5-50 μM for cytotoxicity on glioma cell lines). NEO212 is a conjugate of temozolomide (TMZ) with the natural product perillyl alcohol (POH) and circumvents TMZ-resistance in multiple cancer cell lines and gliomas. Uses: Dna alkylating agent. Synonyms: NEO 212; NEO212; NEO-212; [(4S)-4-Isopropenyl-1-cyclohexen-1-yl]methyl [(3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazin-8-yl)carbonyl]carbamate. Grades: 99%. CAS No. 1361198-79-9. Molecular formula: C17H20N6O4. Mole weight: 372.38. BOC Sciences 11
Temozolomide-d3 (3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one-d3) Labeled Temozolomide, an antineoplastic. Group: Biochemicals. Alternative Names: 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one-d3. Grades: Highly Purified. CAS No. 85622-93-1. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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