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4-Thiazolamine Hydrochloride. Group: Biochemicals. Alternative Names: 4-Thiazolamine Monohydrochloride; 4-Aminothiazole Hydrochloride. Grades: Highly Purified. CAS No. 59134-95-1. Pack Sizes: 250mg. Molecular Formula: C3H5ClN2S, Molecular Weight: 135.99. US Biological Life Sciences.
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5-Thiazolamine
5-Thiazolamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 17721-00-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C3H4N2S. US Biological Life Sciences.
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5-Thiazolamine, 2-methyl-
5-Thiazolamine, 2-methyl-. Group: Biochemicals. Grades: Highly Purified. CAS No. 89281-44-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C4H6N2S. US Biological Life Sciences.
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JK 184 (N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine)
An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC50 = 210 nM). Group: Biochemicals. Alternative Names: N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine. Grades: Highly Purified. CAS No. 315703-52-7. Pack Sizes: 1mg. US Biological Life Sciences.
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2-Amino-2-thiazoline
2-Amino-2-thiazoline. Group: Biochemicals. Alternative Names: 4,5-Dihydro-2-thiazolamine; 2-Imino-thiazolidine; 2-Amino-4,5-dihydro-1,3-thiazole; 2-Amino-4,5-dihydrothiazole; 4,5-Dihydrothiazol-2-amine; 2-Thiazolidinimine; 2-Thiazolin-2-amine; 2-Amino-Δ2-thiazoline; 2-Aminothiazoline; 2-Iminothiazolidine. Grades: Highly Purified. CAS No. 1779-81-3. Pack Sizes: 2.5g. US Biological Life Sciences.
Core binding factors (CBFs) are heterodimeric transcription factors containing a DNA-binding CBFα component (a RUNX protein) and an enhancer of binding, CBF&beta. CBFβ Inhibitor cellular studies indicate a good correlation between the inhibitor's antiproliferative activity and the Runx1 expression level in the target cells. Synonyms: Core Binding Factor-β Inhibitor; 2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)-; 5-Ethyl-4-(4-methoxyphenyl)-2-thiazolamine; Sc 221405; 5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine. Grades: ≥98%. CAS No. 493028-20-9. Molecular formula: C12H14N2OS. Mole weight: 234.32.
CGH 2466 dihydrochloride
CGH 2466 dihydrochloride is an adenosine A1, A2B and A3 receptor antagonist (IC50 = 19, 21, and 80 nM, respectively). It also displays an inhibitory effect on p38 MAPK (IC50 = 187 - 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 is potentially used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Uses: Potential treatment of asthma and copd. Synonyms: CGH 2466 dihydrochloride; CGH2466 dihydrochloride; CGH-2466 dihydrochloride; 4-(3,4-Dichlorophenyl)-5-(4-pyridinyl)-2-thiazolamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1177618-54-0. Molecular formula: C14H9N3SCl2.2HCl. Mole weight: 395.13.
Cyc-116
Heterocyclic Organic Compound. Alternative Names: 5-[2,5-Dihydro-2-[[4-(4-morpholinyl)phenyl]imino]-4-pyrimidinyl]-4-methyl-2-thiazolamine. CAS No. 1059105-22-4. Molecular formula: C18H20N6OS. Catalog: ACM1059105224.
CYC-116
An Aurora kinase inhibitor, used to treat patients with advanced solid tumors. Group: Biochemicals. Alternative Names: 5-[2, 5-Dihydro-2-[[4- (4-morpholinyl) phenyl]imino]-4-pyrimidinyl]-4-methyl-2-thiazolamine. Grades: Highly Purified. CAS No. 1059105-22-4. Pack Sizes: 5mg. US Biological Life Sciences.
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FLT3 Inhibitor III
FLT3 Inhibitor III, a cell-permeable 5-phenyl-2-thiazolamine compound, is a potent inhibitor of Fms-like tyrosine kinase 3 (FLT3) with an IC50 of 50 nM. It displays high selectivity for FLT3 over a panel of 300 other kinases. Synonyms: Fms-like Tyrosine Kinase Inhibitor III; (5-Phenyl-thiazol-2-yl)-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-amine; 5-Phenyl-N-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-thiazolamine; 5-Phenyl-N-(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-2-thiazolamine; (5-Phenyl-thiazol-2-yl)-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-amine. Grades: ≥98%. CAS No. 852045-46-6. Molecular formula: C21H23N3OS. Mole weight: 365.5.
NS 19504
NS 19504 is an activator of large-conductance Ca2+-activated potassium channels. It has relaxing effects on bladder smooth muscle. Synonyms: NS 19504; NS19504; NS-19504; 5-[(4-Bromophenyl)methyl]-2-thiazolamine. Grades: ≥99% by HPLC. CAS No. 327062-46-4. Molecular formula: C10H9BrN2S. Mole weight: 269.16.
PD-118440
PD-118440 is a dopamine antagonist. It was identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests including [3H]-haloperidol and [3H]-N-propylnorapomorphine binding. It inhibits striatal DA synthesis, DA neuronal firing and spontaneous locomotor activity. Synonyms: 2-Amino-4-[(1-propyl-1,2,5,6-tetrahydropyridin)-3-yl]thiazole;2-Thiazolamine,4-(1,2,5,6-tetrahydro-1-propyl-3-pyridinyl)-;4-(1-propyl-3,6-dihydro-2H-pyridin-5-yl)-1,3-thiazol-2-amine; PD118440; PD 118440; PD118440. Grades: >98%. CAS No. 108351-90-2. Molecular formula: C11H17N3S. Mole weight: 223.33.
PD-120697
PD-120697 is a novel dopamine antagonist with central dopamine agonist properties. It was identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests including [3H]-haloperidol and [3H]-N-propylnorapomorphine binding. It inhibits striatal DA synthesis, DA neuronal firing and spontaneous locomotor activity. Synonyms: PD-120697; PD120697; PD 120697; 4-(1,2,5,6-Tetrahydro-1-allyl-3-pyridinyl)-2-thiazolamine;2-Thiazolamine, 4-[1,2,5,6-tetrahydro-1-(2-propen-1-yl)-3-pyridinyl]-;4-(1-Prop-2-enyl-3,6-dihydro-2H-pyridin-5-yl)-1,3-thiazol-2-amine;PD120697;4-(1-Allyl-1,2,5,6-tetrahydropyridin-3-yl)thiazol-2-amine. Grades: >98%. CAS No. 108351-91-3. Molecular formula: C11H15N3S. Mole weight: 221.32.
UCLA GP130 2
UCLA GP130 2 is a brain-penetrant gp130 agonist, protecting against NMDA-induced toxicity in primary hippocampal neurons in vitro, and increasing STAT3 phosphorylation in SH-SY5Y cells. Synonyms: N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine. Grades: ≥98% by HPLC. CAS No. 339303-87-6. Molecular formula: C15H11FN2S. Mole weight: 270.32.
2-Amino-5-(trifluoromethyl)-4-thiazolecarboxylic Acid is a derivative of 2-Aamino-4-thiazolecarboxylic Acid Ethyl Ester (E678465), a chemical reagent used in the preparation fo SAR thiazolamino arylaminopyrimidines as anaplastic lymphoma kinase inhibitors. As well as in the synthesis of 4-bicyclick piperadine derivatives as potent stearoyl-CoA desaturase (SCD1) inhibitors in the treatment of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 1086380-23-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C5H3F3N2O2S, Molecular Weight: 212.15. US Biological Life Sciences.
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