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| Product | Description | |
|---|---|---|
| 2-Thiazolidinone | 2-Thiazolidinone is used in the synthesis of (S)-4-iso-butylthiazolidin-2-one and (S)-4-benzylthiazolidin-2-one that show inhibitive activities against Candida albicans and Escherichia coli. Group: Biochemicals. Grades: Highly Purified. CAS No. 2682-49-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C3H5NOS, Molecular Weight: 103.14. US Biological Life Sciences. |  Worldwide |
| 3-? (4-?Methoxyphenyl) ?-?5-?[ (5-?nitro-?2-?thienyl) ?methylene]?-?2-?thioxo-4-?thiazolidinone | 3-? (4-?Methoxyphenyl) ?-?5-?[ (5-?nitro-?2-?thienyl) ?methylene]?-?2-?thioxo-4-?thiazolidinone is a protein disulfide isomerases (PDI) inhibitor. PDIs are involved with protein folding in the endoplasmic reticulum. PDI inhibitors are potential anticancer agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 346640-08-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C15H10N2O4S3, Molecular Weight: 378.45. US Biological Life Sciences. | Worldwide |
| 4-Thiazolidinone,3-ethyl-5-[1-(2-hydroxyethyl)-4(1H)-pyridinylidene]-2-thioxo- | 4-Thiazolidinone,3-ethyl-5-[1-(2-hydroxyethyl)-4(1H)-pyridinylidene]-2-thioxo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 250-925-0, CID169405, 3-Ethyl-5-(1-(2-hydroxyethyl)-4(1H)-pyridylidene)rhodanine, 4-Thiazolidinone, 3-ethyl-5-(1-(2-hydroxyethyl)-4(1H)-pyridinylidene)-2-thioxo-, 32112-80-4. Product Category: Heterocyclic Organic Compound. CAS No. 32112-80-4. Molecular formula: C12H14N2O2S2. Mole weight: 282.38176. Purity: 0.96. IUPACName: 3-ethyl-5-[1-(2-hydroxyethyl)pyridin-4-ylidene]-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: CCN1C(=O)C(=C2C=CN(C=C2)CCO)SC1=S. Density: 1.44g/cm³. ECNumber: 250-925-0. Product ID: ACM32112804. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 4-Thiazolidinone,5-[[2-chloro-3-[(3-ethyl-2(3H)-benzothiazolylidene)ethylidene]-1-cyclohexen-1-yl]methylene]-3-ethyl-2-thioxo- | 4-Thiazolidinone,5-[[2-chloro-3-[(3-ethyl-2(3H)-benzothiazolylidene)ethylidene]-1-cyclohexen-1-yl]methylene]-3-ethyl-2-thioxo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-THIAZOLIDINONE, 5-[[2-CHLORO-3-[(3-ETHYL-2(3H)-BENZOTHIAZOLYLIDENE)ETHYLIDENE]-1-CYCLOHEXEN-1-YL]METHYLENE]-3-ETHYL-2-THIOXO-;5-[(Z)-(2-CHLORO-3-((E)-2-[3-ETHYL-1,3-BENZOTHIAZOL-2(3H)-YLIDENE]ETHYLIDENE)-1-CYCLOHEXEN-1-YL)METHYLIDENE]-3-ETHYL-2-THIOXO-. Product Category: Heterocyclic Organic Compound. CAS No. 69415-10-7. Molecular formula: C23H23ClN2OS3. Mole weight: 475.09. Product ID: ACM69415107. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Thiazolidinone,5-[(3,4-dimethoxyphenyl)methylene]-2-thioxo- | 4-Thiazolidinone,5-[(3,4-dimethoxyphenyl)methylene]-2-thioxo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: NSC31101, CID2787035, 6326-74-5. Product Category: Heterocyclic Organic Compound. CAS No. 6326-74-5. Molecular formula: C12H11NO3S2. Mole weight: 281.35. Purity: 0.96. IUPACName: 5-[(3,4-dimethoxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: COC1=C(C=C(C=C1)C=C2C(=O)NC(=S)S2)OC. Density: 1.41g/cm³. Product ID: ACM6326745. Alfa Chemistry ISO 9001:2015 Certified. Categories: (5E)-5-(3,4-dimethoxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one. | |
| 4-Thiazolidinone,5-[4-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-phenyl-2-buten-1-ylidene]-3-ethyl-2-thioxo- | 4-Thiazolidinone,5-[4-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-phenyl-2-buten-1-ylidene]-3-ethyl-2-thioxo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-ETHYL-5-[(E,2E)-1-PHENYL-4-(1,3,3-TRIMETHYL-1,3-DIHYDRO-2H-INDOL-2-YLIDENE)-2-BUTENYLIDENE]-2-THIOXO-1,3-THIAZOLIDIN-4-ONE;RHODANINE, 3-ETHYL-5-[1-PHENYL-4-(1,3,3-TRIMETHYL-2-INDOLINYLIDENE)-2-BUTENYLIDENE]-. Product Category: Heterocyclic Organic Compound. CAS No. 14664-55-2. Molecular formula: C26H26N2OS2. Mole weight: 446.63. Density: 1.28g/cm³. Product ID: ACM14664552. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-(3-Methyl-2(3H)-benzothiazolylidene)-3-(phenylmethyl)-2-thioxo-4-thiazolidinone | 5-(3-Methyl-2(3H)-benzothiazolylidene)-3-(phenylmethyl)-2-thioxo-4-thiazolidinone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 79610-23-4, 4-Thiazolidinone, 5-(3-methyl-2(3H)-benzothiazolylidene)-3-(phenylmethyl)-2-thioxo-, AC1LR433, CTK8D4192, 5-(3-methyl-2(3H)-benzothiazolylidene)-3-(phenylmethyl)-2-thioxo-4-Thiazolidinone, (5Z)-3-benzyl-5-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)-2-thioxo-1,3-thiazolidin-4-one, ACT06504, MCULE-3099375373, A15815, (E)-3-benzyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-2-thioxothiazolidin-4-one, 3-benzyl-5-(3-methyl-1,3-benzothiazol-2-ylidene)-2-sulfanylidene-1,3-thiazolidin-4-one, (5E)-3-benzyl-5-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)-2-thioxo-1,3-thiazolidin-4-one. Product Category: Heterocyclic Organic Compound. CAS No. 79610-23-4. Molecular formula: C18H14N2OS3. Mole weight: 370.511560 [g/mol]. Purity: 0.96. IUPACName: 3-benzyl-5-(3-methyl-1,3-benzothiazol-2-ylidene)-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: CN1C2=CC=CC=C2SC1=C3C(=O)N(C(=S)S3)CC4=CC=CC=C4. Product ID: ACM79610234. Alfa Chemistry ISO 9001:2015 Certified. | |
| CFTR Inhibitor-172 (CFTRinh-172, 3-[ (3-Trifluoromethyl) phenyl]-5-[ (4-carboxyphenyl) methylene]-2-thioxo-4-thiazolidinone) | A cell-permeable 2-thio-4-thiazolidinone compound that acts as a potent, reversible, rapid, and voltage-independent inhibitor of CFTR (cystic fibrosis transmembrane conductance regulator)-mediated Cl- transport in human airway cells (Ki ~300nM). It does not prevent elevation of cellular cAMP, nor does it inhibit non-CFTR Cl- channels, MDR-1, ATP-sensitive K+ channels, or a series of other transporters even at concentrations as high as 5uM. Shown to block cholera toxin-induced intestinal fluid secretion in mice. May be also useful for reducing intestinal fluid loss in other secretory diarrheas. Group: Biochemicals. Grades: Highly Purified. CAS No. 307510-92-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| TC HSD 21 (5-[ (3-Bromo-4-hydroxyphenyl) methylene]-3- (4-methoxyphenyl) -2-thioxo-4-thiazolidinone) | Potent 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3) inhibitor (IC50 values are 6 and 40nm at human and mouse 17beta-HSD3 respectively). Displays no activity at 17beta-HSD1, 17beta-HSD2, ERalpha, androgen receptors or glucocorticoid receptors. Group: Biochemicals. Grades: Highly Purified. CAS No. 330203-01-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| ZK-Thiazolidinone | ZK-Thiazolidinone, also known as TAL, is an ATP-competitive inhibitor of PLK1. In vitro, ZK-Thiazolidinone counteracts the role of Plk1 in previously established functions, notably, sister chromatid separation, centrosome maturation, and bipolar spindle assembly. Synonyms: TAL. Grades: 98%. CAS No. 891849-87-9. Molecular formula: C23H30F3N5O2S. Mole weight: 497.58. |  |
| 2,?4-?Difluoronitrobenzene | 2,?4-?Difluoronitrobenzene is a reactant in the preparation of 4-?thiazolidinone derivatives as antimicrobial agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 446-35-5. Pack Sizes: 100g, 250g. Molecular Formula: C6H3F2NO2, Molecular Weight: 159.09. US Biological Life Sciences. | Worldwide |
| 2-Amino-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-4(5H)-thiazolone | 2-Amino-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-4(5H)-thiazolone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-AMINO-5-[4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL]-4(5H)-THIAZOLONE;2-AMINO-5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOL-4-ONE;5-{4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL}-2-AMINO-4-THIAZOLIDINONE;5-{4-[2-(5-ETHYL-2-PYRIDYL)ETHOXY]BENZYL}-2-IMINO-4. Product Category: Heterocyclic Organic Compound. Appearance: Tan Solid. CAS No. 105355-26-8. Molecular formula: C19H21N3O2S. Mole weight: 355.45. Density: 1.28. Product ID: ACM105355268. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3-(4-Chloro-3-methylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one | 3-(4-Chloro-3-methylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(4-Chloro-m-tolyl)rhodanine, Rhodanine, 3-(4-chloro-m-tolyl)-, NSC 290702, 21494-77-9, 4-thiazolidinone, 3-(4-chloro-3-methylphenyl)-2-thioxo-, NSC290702, AC1L2JCB, AC1Q7FE4, CTK4E6966, AR-1G4797, AG-J-11251, NSC-290702, LS-143580, 3-(4-chloro-3-methylphenyl)-2-thioxo-1,3-thiazolidin-4-one, 3-(4-chloro-3-methylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one. Product Category: Heterocyclic Organic Compound. CAS No. 21494-77-9. Molecular formula: C10H8ClNOS2. Mole weight: 257.76 g/mol. Purity: 0.96. IUPACName: 3-(4-chloro-3-methylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one. Density: 1.51g/cm³. Product ID: ACM21494779. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3-Allylrhodanine | 3-Allylrhodanine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-ALLYLRHODANINE;3-ALLYL-2-THIOXO-4-THIAZOLIDINONE;3-ALLYL-4-OXO-2-THIOXO-THIAZOLIDINE;N-ALLYLRHODANINE;Allylrhodanine;3-Allyl-2-thioxo-thiazolidin-4-one;3-ALLYLRHODANINE 99%;2-allylrhodanine. Product Category: Heterocyclic Organic Compound. Appearance: yellow crystals. CAS No. 1457-47-2. Molecular formula: C6H7NOS2. Mole weight: 173.26. Purity: 0.96. IUPACName: 3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: C=CCN1C(=O)CSC1=S. Density: 1.35g/cm³. ECNumber: 215-941-4. Product ID: ACM1457472. Alfa Chemistry ISO 9001:2015 Certified. | |
| 3-Ethyl-5-[1-(3-methyl-1,3-thiazolidin-2-ylidene)propan-2-ylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | 3-Ethyl-5-[1-(3-methyl-1,3-thiazolidin-2-ylidene)propan-2-ylidene]-2-sulfanylidene-1,3-thiazolidin-4-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 244-152-8, CID89415, 3-Ethyl-5-(1-methyl-2-(3-methyl-2-thiazolidene)ethylidene)rhodanine, 3-Ethyl-5-(1-methyl-2-(3-methylthiazolidin-2-ylidene)ethylidene)rhodanine, 3-Ethyl-5-(1-methyl-2-(3-methyl-2-thiazolidinylidene)ethylidene)-2-thioxo-4-thiazolidinone, 21025-18-3, 4-Thiazolidinone, 3-ethyl-5-(1-methyl-2-(3-methyl-2-thiazolidinylidene)ethylidene)-2-thioxo-. Product Category: Heterocyclic Organic Compound. CAS No. 21025-18-3. Molecular formula: C12H16N2OS3. Mole weight: 300.463 g/mol. Purity: 0.96. IUPACName: 3-ethyl-5-[1-(3-methyl-1,3-thiazolidin-2-ylidene)propan-2-ylidene]-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: CCN1C(=O)C(=C(C)C=C2N(CCS2)C)SC1=S. ECNumber: 244-152-8. Product ID: ACM21025183. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one | 5-[1-(4-Nitro-phenyl)-meth-(Z)-ylidene]-2-thioxo-thiazolidin-4-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4120-64-3, AC1MDKLM, (5E)-2-mercapto-5-(4-nitrobenzylidene)-1,3-thiazol-4(5H)-one, CTK4I4416, AG-F-46527, MCULE-8188950574, 4-Thiazolidinone,5-[(4-nitrophenyl)methylene]-2-thioxo-, 5-[(4-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Rhodanine,5-(p-nitrobenzylidene)- (6CI,7CI,8CI);5-(4-Nitrobenzylidene)-2-thioxothiazolidin-4-one; 5-(p-Nitrobenzylidene)rhodanine;NSC 108804. Product Category: Heterocyclic Organic Compound. CAS No. 4120-64-3. Molecular formula: C10H6N2O3S2. Mole weight: 266.29624. Purity: 0.96. IUPACName: 5-[(4-nitrophenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: C1=CC(=CC=C1C=C2C(=O)NC(=S)S2)[N+](=O)[O-]. Density: 1.6g/cm³. Product ID: ACM4120643. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5-(4-Nitro-benzylidene)-2-thioxo-thiazolidin-4-one. | |
| 5-[(3,5-Ditert-butyl-4-hydroxyphenyl)methyl]-1,3-thiazolidin-4-one | 5-[(3,5-Ditert-butyl-4-hydroxyphenyl)methyl]-1,3-thiazolidin-4-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tazofelone (USAN/INN); (+)-5-<<3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl>methyl>-4-thiazolidinone; Tazofelone; UNII-VH2I1JN8Q1; 5-(3,5-di-tert-butyl-4-hydroxybenzyl)-1,3-thiazolidin-4-one. Product Category: Heterocyclic Organic Compound. CAS No. 136433-51-7. Molecular formula: C18H27NO2S. Mole weight: 321.477 g/mol. Purity: 0.96. IUPACName: 5-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-1,3-thiazolidin-4-one. Canonical SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC2C(=O)NCS2. Density: 1.105g/cm³. Product ID: ACM136433517. Alfa Chemistry ISO 9001:2015 Certified. | |
| 5-(4-Iodobenzylidene)-2-thioxothiazolidin-4-one | 5-(4-Iodobenzylidene)-2-thioxothiazolidin-4-one, a chemical compound of interest in biomedical research, displays promising potential as an anti-tumor agent. In light of current findings, future drug development may witness the integration of this compound for the treatment of various forms of cancer. Besides, its antibacterial and antifungal properties have also been examined, reflecting its plausible utilization as a novel therapeutic entity in the domain of infectious diseases. Synonyms: (E)-5-(4-Iodobenzylidene)-2-thioxothiazolidin-4-one; 5-(4-iodobenzylidene)rhodanine; (5E)-5-(4-Iodobenzylidene)-2-thioxo-1,3-thiazolidin-4-one; 4-Thiazolidinone, 5-[(4-iodophenyl)methylene]-2-thioxo-, (5E)-. CAS No. 90947-00-5. Molecular formula: C10H6INOS2. Mole weight: 347.19. | |
| 5-[(6-Ethoxy-1-ethyl-(1H)-quinolin-2-ylidene)ethylidene]-3-ethyl-2-thioxothiazolidin-4-one | 5-[(6-Ethoxy-1-ethyl-(1H)-quinolin-2-ylidene)ethylidene]-3-ethyl-2-thioxothiazolidin-4-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EINECS 271-171-9, CID6437558, 4-Thiazolidinone, 5-((6-ethoxy-1-ethyl-2(1H)-quinolinylidene)ethylidene)-3-ethyl-2-thioxo-, 4-Thiazolidinone, 5-(2-(6-ethoxy-1-ethyl-2(1H)-quinolinylidene)ethylidene)-3-ethyl-2-thioxo-, 5-((6-Ethoxy-1-ethyl-(1H)-quinolin-2-ylidene)ethylidene)-3-ethyl-2-thioxothiazolidin-4-one, 5-(2-(6-Ethoxy-1-ethyl-2(1H)-quinolinylidene)ethylidene)-3-ethyl-2-thioxo-4-thiazolidinone, 68516-67-6. Product Category: Heterocyclic Organic Compound. CAS No. 68516-67-6. Molecular formula: C20H22N2O2S2. Mole weight: 386.530880 [g/mol]. Purity: 0.96. IUPACName: (5Z)-5-[(2E)-2-(6-ethoxy-1-ethylquinolin-2-ylidene)ethylidene]-3-ethyl-2-sulfanylidene-1,3-thiazolidin-4-one. Canonical SMILES: CCN1C(=CC=C2C(=O)N(C(=S)S2)CC)C=CC3=C1C=CC(=C3)OCC. Density: 1.3g/cm³. ECNumber: 271-171-9. Product ID: ACM68516676. Alfa Chemistry ISO 9001:2015 Certified. | |
| AM-TS23 | AM-TS23 has been found to be a DNA polymerase λ and β inhibitor and could be effective in studies of colorectal cancer. Synonyms: AM-TS23; AM TS23; AMTS23; (5Z)-5-[[(4-[(2-Methylphenyl)thio]-3-nitrophenyl]methylene]-2-thioxo-4-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 1489285-17-7. Molecular formula: C17H12N2O3S3. Mole weight: 388.48. | |
| CCF-642 | CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable to the first-line multiple myeloma therapeutic bortezomib. Synonyms: 3-(4-Methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone; CCF-642; CCF 642; CCF642. CAS No. 346640-08-2. Molecular formula: C15H10N2O4S3. Mole weight: 378.44. | |
| CCR-11 | CCR-11. Group: Biochemicals. Alternative Names: 2-Thioxo-5-[[5-[3- (trifluoromethyl) phenyl]-2-furanyl]methylene]-4-thiazolidinone. Grades: Highly Purified. CAS No. 301687-87-6. Pack Sizes: 10mg. Molecular Formula: C15H8F3NO2S2, Molecular Weight: 355.35. US Biological Life Sciences. | Worldwide |
| CK 869 | CK 869 has been found to inhibit actin polymerization as well as human and bovine actin-related protein 2/3 (Arp2/3) complex. Synonyms: CK-869; CK 869; CK869; CK-0157869; CK 0157869; CK0157869; 2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 388592-44-7. Molecular formula: C17H16BrNO3S. Mole weight: 394.28. | |
| CYM 50308 | CYM 50308 has been found to be an effective and selective S1P4 agonist. Synonyms: CYM-50308; CYM 50308; CYM50308. (2Z,5Z)-5-[[1-(2,4-Difluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]methylene]-2-[(2-methoxyethyl)imino]-3-methyl-4-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 1345858-76-5. Molecular formula: C20H21F2N3O2S. Mole weight: 405.46. | |
| Fmoc-L-valine | Fmoc-valine is a sterically hindered, Fmoc-protected amino acid and is a derivative of L-Valine. Fmoc-valine (in addition to the other amino acids) is commonly used to synthesize 4-thiazolidinones and 4-metathiazanones as well. Synonyms: Fmoc-L-Val-OH; (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid; FMco-Val-OH; N-FMOC-L-VAL; FMOC-L-VAL; FMOC-VAL. Grades: ≥ 99.7% (HPLC, Chiral purity). CAS No. 68858-20-8. Molecular formula: C20H21NO4. Mole weight: 339.40. | |
| Latrunculin A | Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges. It is a disruptor of microfilament-mediated processes. It is also an actin assembly and polymerization inhibitor. Synonyms: Latrunculin A; Latrunculin-A; 4-[(1R,4Z,8E,10Z,12S,15R, 17R)-17-Hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl)-2-thiazolidinone. Grades: ≥98% by HPLC. CAS No. 76343-93-6. Molecular formula: C22H31NO5S. Mole weight: 421.55. | |
| Latrunculin b | Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-Hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone. Product Category: Inhibitors. Appearance: Oil. CAS No. 76343-94-7. Molecular formula: C20H29NO5S. Mole weight: 395.5. Purity: 95%+. IUPACName: (4R)-4-[(1R,4Z,8Z,10S,13R,15R)-15-Hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-1,3-thiazolidin-2-one. Canonical SMILES: CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=C1)C. Product ID: ACM76343947. Alfa Chemistry ISO 9001:2015 Certified. | |
| Latrunculin B | Latrunculin B is a marine toxin which acts as an inhibitor of actin polymerization. It causes concentration-dependent changes in cell shape and actin organization. Synonyms: Latrunculin B; LAT-B; LATB; LAT B; NSC 339663; NSC-339663; NSC339663; (4R)-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-2-thiazolidinone. Grades: ≥97% by HPLC. CAS No. 76343-94-7. Molecular formula: C20H29NO5S. Mole weight: 395.51. | |
| Leukadherin-1 (aMb2 Agonist II, CD11b Agonist II, LA1, Mac-1 Agonist II, CR3 Agonist II, CD11b/CD18 Agonist, 4-(5-((3-Benzyl-4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl)furan-2-yl)-benzoic Acid) | A furanyl thiazolidinone compound that binds CD11b aA/aI domain in a reversible manner and stabilizes aA in a high-affinity binding conformation toward known CD11b/CD18 (aMB2; CR3; Mac-1) ligands, fibrinogen, ICAM-1, and iC3B. Reported to be superior to IMB-10 in enhancing Mac-1-mediated cell adhesion (EC50=4 vs. >50uM on fibrinogen surface). Effectively suppresses leukocyte recruitment in various inflammatory disease models involving mice, rats, and zebrafish embryos in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| LY-178002 | LY-178002 is a phospholipase A2 inhibitor. It also inhibits leukotriene B4 production. Synonyms: LY 178002; LY178002; LY-178002. 5-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]thiazolidin-4-one;5-(3,5-Bis(tert-butyl)-4-hydroxyphenyl)methylene-4-thiazolidinone;4-Thiazolidinone, 5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-. Grades: >98%. CAS No. 107889-32-7. Molecular formula: C18H25NO2S. Mole weight: 319.46. | |
| LY 221068 | LY 221068 is a Lipoxygenase inhibitor originated by Eli Lilly. It is a potent antioxidant with antiinflammatory properties. But no development was reported for Rheumatic disorders in USA. Uses: Rheumatic disorders. Synonyms: LY 221068; LY-221068; LY221068; 5-((3,5-Bis(1,1,-dimethylethyl)-4-hydroxyphenyl)methylene)-3-(dimethylamino)-4-thiazolidinone. Grades: 98%. CAS No. 132392-39-3. Molecular formula: C20H30N2O2S. Mole weight: 362.54. | |
| LY-256548 | LY-25648 is a leukotriene B4 antagonist. Synonyms: LY 25648; LY-25648; LY25648; Dihydro-3-methyl-5-(4-hydroxy-3,5-ditert-butylbenzylidene)thiazol-4(5H)-one;LY25648;5-(3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene-N-methyl-4-thiazolidinone;(5Z)-5-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-3-methyl-1,3-thiazolidin-4-one. Grades: >98%. CAS No. 107889-31-6. Molecular formula: C19H27NO2S. Mole weight: 333.49. | |
| LY 269415 | LY 269415 is a 5-Lipoxygenase inhibitor originated by Eli Lilly. It is a potent antioxidant with antiinflammatory properties in vitro. But no development was reported for Rheumatic disorders in USA. Uses: Rheumatic disorders. Synonyms: LY 269415; LY269415; LY-269415. 5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-3-(methylamino)-4-Thiazolidinone. Grades: 98%. CAS No. 132392-65-5. Molecular formula: C19H28N2O2S. Mole weight: 348.51. | |
| Necrostatin-7 | Necrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase. Uses: Designed for use in research and industrial production. Additional or Alternative Names: STK763743, necrotatin-7, Necrostatin-7, AC1LOGUN, Nec-7, CHEMBL514242, HMS621M06, MolPort-002-708-930, ZINC20587175, AKOS001738191, A2363/0099838, 5-[3-(4-Fluoro-phenyl)-1H-pyrazol-4-ylmethylene]-2-imino-[2,3]bithiazolyl-4-one, (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one, (5Z)-5-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene}-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one, 351062-08-3, 5-[[3-(4-Fluorophenyl)-1H-pyrazol-4-yl]methylene]-2-imino-3-(2-thiazolyl)-4-thiazolidinone. Product Category: Inhibitors. Appearance: Solid. CAS No. 351062-08-3. Molecular formula: C16H10FN5OS2. Mole weight: 371.41. Purity: 0.96. IUPACName: (5Z)-5-[[5-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene]-2-imino-3-(1,3-thiazol-2-yl)-1,3-thiazolidin-4-one. Canonical SMILES: C1=CC(=CC=C1C2=C(C=NN2)C=C3C(=O)N(C(=N)S3)C4=NC=CS4)F. Product ID: ACM351062083. Alfa Chemistry ISO 9001:2015 Certified. | |
| Optovin | Optovin is a reversible photoactive TRPA1 activator; stimulates human TRPA1 channels in vitro and enables repeated photoactivation of motor behaviors in wild-type zebrafish (EC50 = 2 μM). Synonyms: Optovin; 348575-88-2; Oprovin; 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-2-thioxo-4-thiazolidinone; SCHEMBL14305788; 5-((2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-2-thioxothiazolidin-4-one; CHEBI:137470; HMS3886J04; 5-{[2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one; YNA57588; CCG-14653; MFCD02219276; AKOS000337708; BIM-0018214.P001; S8073; SW219786-1; AB00104090-01; SR-01000230413; SR-01000230413-1. Grades: >98%. CAS No. 348575-88-2. Molecular formula: C15H13N3OS2. Mole weight: 315.41. | |
| PFM 01 | PFM 01, a cell-permeable N-alkylated Mirin derivative, is a nuclease-specific MRE11 inhibitor, which enhances non-homologous end-joining (NHEJ) and reduces homologous recombination. Synonyms: (5Z)-5-[(4-Hydroxyphenyl)methylene]-3-(2-methylpropyl)-2-thioxo-4-thiazolidinone; PFM01; PFM-01; PFM 01. Grades: ≥98% by HPLC. CAS No. 1558598-41-6. Molecular formula: C14H15NO2S2. Mole weight: 293.4. | |
| Pioglitazone 2-Imine | Pioglitazone impurity. Group: Biochemicals. Alternative Names: 2-Amino-5-[[4-[2- (5-ethyl-2-pyridinyl) ethoxy]phenyl]methyl]-4 (5H) -thiazolone; 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]-2-imino-4-thiazolidinone. Grades: Highly Purified. CAS No. 105355-26-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Pioglitazone HCl | 5-{4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]Benzyl}-2-Imino-4-Thiazolidinone HCl. Antihypertensive. CAS No. 112529-15-4. Product ID: 8-01810. Molecular formula: C19H20N2O3S.HCl. Mole weight: 392.9. |  |
| Ponesimod | Ponesimod is an orally active and selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator that acts as a functional antagonist. It has potential immunomodulating activity. It may be used as a new therapeutic approach in lymphocyte-mediated autoimmune diseases. It is also an experimental drug for the treatment of multiple sclerosis (MS) and psoriasis. It protects against lymphocyte-mediated tissue inflammation. It activated S1P(1)-mediated signal transduction with high potency (EC(50) of 5.7 nM) and selectivity in vitro. It prevented edema formation, inflammatory cell accumulation and cytokine release in the skin of mice with delayed-type hypersensitivity. It also prevented t...tal drug for the treatment of multiple sclerosis (ms) and psoriasis. Synonyms: ACT-128800; ACT 128800; ACT128800; Ponesimod. (2Z,5Z)-5-(3-chloro-4-((R)-2,3-dihydroxypropoxy)benzylidene)-2-(propyliMino)-3-(o-tolyl)thiazolidin-4-one;4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]Methylene]-3-(2-Methylphenyl)-2-(propyliMino)-, (2Z,5Z)-;ACT-128800;5-[3-Chloro-4-[((2R)-2,3-dihydroxypropyl)oxy]benz-(Z)-ylidene]-2-((Z)-propylimino)-3-(o-tolyl)thiazolidin-4-one;(5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-one. Grades: ≥ 95.0%. CAS No. 854107-55-4. Molecular formula: C23H25ClN2O4S. Mole weight: 460.97. | |
| PRL-3 Inhibitor (BR-1, P0108, Phosphatase of Regenerating Liver 3 Inhibitor, PTP4A3 Inhibitor) | Phosphatase of regenerating liver 3 (PRL-3, also known as PTP4A3) plays critical roles in cell proliferation, motility, and invasion, and thus contributes to cancer metastasis. PRL-3 inhibitor is a cell-permeable benzylidene rhodamine that inhibits PRL-3 (IC50=900nM for human PRL-3 in vitro), with minimal activity against other phosphatases. It reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay. PRL-3 inhibitor has been used to elucidate the actions of this enzyme, demonstrating that it dephosphorylates Tyr783 on integrin beta1 and modulates VEGF-mediated endothelial cell migration. It dose-dependently inhibits the growth and triggers apoptosis in cancer cell lines. Group: Biochemicals. Alternative Names: 5-[[5-bromo-2-[(2-bromophenyl) methoxy] phenyl] methylene] -2- thioxo-4-thiazolidinone. Grades: Highly Purified. CAS No. 893449-38-2. Pack Sizes: 1mg, 5mg, 10mg, 25mg. Molecular Formula: C17H11Br2NO2S2. US Biological Life Sciences. | Worldwide |
| TC HSD 21 | TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor (IC50 = 6 and 40 nM at human and mouse 17β-HSD3, respectively) with no activity at 17β-HSD1, 17β-HSD2, ERα, androgen receptors or glucocorticoid receptors. Synonyms: TC HSD 21; TC-HSD-21; TCHSD21; TC-HSD 21; 5-[(3-Bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone. Grades: ≥99% by HPLC. CAS No. 330203-01-5. Molecular formula: C17H12BrNO3S2. Mole weight: 422.32. | |
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