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| Product | Description | |
|---|---|---|
| 1,4-BDMT | Benzylic thiol scavenger used in TFA cleavages of peptide resins. Group: Thiol scavengers. Alternative Names: 1,4-Benzenedimethanethiol. CAS No. 105-09-9. |  Luxembourg Bio Technologies |
| Fmoc-Cys(tButhio)-OH | Building block for introduction of cysteinyl residues by Fmoc SPPS. The t-Buthio group can be selectively removed using thiols or tributylphosphine. This protecting group is stable to TFA if thiol scavengers are not used. Uses: Peptide synthesis. Additional or Alternative Names: Fmoc-Cys(tButhio)-OH, N-α-Fmoc-S-t.-butylthio-L-cysteine. Product Category: Amino Acids. CAS No. 73724-43-3. Molecular formula: C22H25NO4S2. Mole weight: 431.57. Product ID: ACM73724433-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Oxidation-Reduction Compound Library | A unique collection of 1279 compounds with defined prooxidant or antioxidant activity can be used for HTS and HCS; - Contains hydroperoxides, polyphenolics, metal chelators, thiols, thiol traps, radical scavengers, lazaroids and glutathione modulators as well as small molecule enzyme mimetics for SOD and glutathione peroxidase, and antioxidant natural products, etc. ?- Structurally diversified with potent bioactivity and cell permeable; - Detailed compound information with structure, target, and biological activity description?- NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2900. Categories: Oxidation-Reduction Compounds Libraries. |  |
| Amifostine | Amifostine is a phosphorylated aminosulfhydryl compound. After dephosphorylation of amifostine by alkaline phosphatase to an active free sulfhydryl (thiol) metabolite, the thiol metabolite binds to and detoxifies cytotoxic platinum-containing metabolites of cisplatin and scavenges free radicals induced by cisplatin and ionizing radiation. The elevated activity of this agent in normal tissues results from both the relative abundance of alkaline phosphatase in normal tissues and the greater vascularity of normal tissues compared to tumor tissues. Uses: Radiation-protective agents. Synonyms: Ethyol; WR2721; WR 2721; WR-2721. Grades: >98%. CAS No. 20537-88-6. Molecular formula: C5H15N2O3PS. Mole weight: 214.22. |  |
| Polystyrene A Sulfonyl Chloride | This polymer-bound alkylsulfonyl chloride resin is an equivalent to alkyl sulfonic chloride and can be used in numerous applications. When this resin is treated with nucleophiles, a variety of polymer-bound sulfonates can be created ( e.g. sulfonyl azides, sulfonyl hydrazine) and subsequently used as polymeric supports, polymer-bound reagents or in catalytic organic synthesis. Uses: Application in the "catch and release" strategy, where the resin catches a compound to form a polymer-bound tosylate. purifying the polymer-bound tosylate by washing and subsequent treatment by a nucleophile releases the target product from the resin. a typical application is to form polymer-bound tosylates by loading alcohols to the resin. treatment with nucleophiles like amines, imidazoles or thiols generates the corresponding sec. or tert. amines, alkylimidazoles or thioethers. this resin can also be used as a scavenger for amines, hydrazines and other nucleophiles. Group: Polymer bound sulfonyl chloride. Alternative Names: Polystyrene Ethyl Sulfonyl Chloride. Pack Sizes: 1g, 5g, 25g. |  |
| Polystyrene Sulfonyl Chloride | This polymer-bound alkylsulfonyl chloride resin is an equivalent to alkyl sulfonic chloride and can be used in numerous applications. When this resin is treated with nucleophiles, a variety of polymer-bound sulfonates can be created ( e.g. sulfonyl azides, sulfonyl hydrazine) and subsequently used as polymeric supports, polymer-bound reagents or in catalytic organic synthesis. Uses: Application in the "catch and release" strategy, where the resin catches a compound to form a polymer-bound tosylate. purifying the polymer-bound tosylate by washing and subsequent treatment by a nucleophile releases the target product from the resin. a typical application is to form polymer-bound tosylates by loading alcohols to the resin. treatment with nucleophiles like amines, imidazoles or thiols generates the corresponding sec. or tert. amines, alkylimidazoles or thioethers. this resin can also be used as a scavenger for amines, hydrazines and other nucleophiles. Group: Polymer bound sulfonyl chloride. Pack Sizes: 5g, 25g, 100g. | |
| WR 1065 | WR 1065 is a metabolite of Amifostine, and a cell-permeable reactive oxygen species scavenger that activates p53 through a JNK-dependent signaling pathway. WR 1065 activates p21waf-1 and MDM2 and inhibits DNA topoisomerase II&alpha. WR 1065 can induce cell cycle arrest and exert cytoprotective activity towards normal cells but not cancer cells in vivo. Synonyms: NSC345308; NSC 345308; NSC-345308; WR1065 Dihydrochloride; WR 1065 Dihydrochloride; WR-1065 Dihydrochloride; 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride; WR 1065 hydrochloride; Amifostine Thiol Dihydrochloride; WR-1065 dihydrochloride. CAS No. 14653-77-1. Molecular formula: C5H14N2S.2HCl. Mole weight: 207.16. | |
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