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| Product | Description | |
|---|---|---|
| thrombin | Formed from prothrombin. More selective than trypsin and plasmin. In peptidase family S1 (trypsin family). Group: Enzymes. Synonyms: fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4143; thrombin; EC 3.4.21.5; 9002-04-4; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: EXWM-4143. |  |
| Thrombin | Thrombin. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Thrombin;Thrombin, bovine. Product Category: Heterocyclic Organic Compound. CAS No. 9002-4-4. Product ID: ACM2594047. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Thrombin from Human, Recombinant | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the final coagulation protease in regard to hemostasis, promoting both pr ocoagulant and anticoagulant effects. Applications: Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. thrombin has been used in a study to assess in vitro hemostatic properties of french lyophilized plasma. Group: Enzymes. Synonyms: thrombin; EC 3.4.21.5; fibrinogenase; thrombas. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Purity: > 95% (SDS-PAGE). Thrombin. Storage: -70°C. Form: aqueous solution; supplied as a solution in 20 mM MES, pH 6.0, 500 mM choline chloride. Source: HEK 293 cells. Species: Human. thrombin; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0702. | |
| Thrombin, Pig blood | Thrombin, Pig blood is a key enzyme in the coagulation cascade, responsible for converting fibrinogen into fibrin. Thrombin, Pig blood activates platelet activation, endothelial cell function, and inflammatory responses by binding to PAR-1 and PAR-4 , which triggers G protein-coupled signaling pathways. Thrombin, Pig blood holds promise for research in coagulation and inflammation fields [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-4-4. Pack Sizes: 100 KU. Product ID: HY-114164C. |  |
| Thrombin Receptor Activator for Peptide TFA | Thrombin Receptor Activator for Peptide TFA is a thrombin receptor activator used in the research of coronary heart disease (CHD). The thrombin receptor is a G protein-coupled receptor involved in the regulation of thrombotic response. Synonyms: Thrombin Receptor Activator for Peptide 5 (TRAP-5) TFA; Coagulation Factor II Receptor (1-5) TFA; Proteinase Activated Receptor 1 (1-5) TFA; H-Ser-Phe-Leu-Leu-Arg-OH.TFA; SFLLR.TFA; L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginine trifluoroacetic acid; TRAP-5 Trifluoroacetate; Thrombin Receptor Activator for Peptide. Grades: ≥95%. CAS No. 2554776-23-5. Molecular formula: C32H51F3N8O9. Mole weight: 748.79. |  |
| Thrombin Receptor Agonist Peptide | Thrombin Receptor Agonist Peptide. Group: Biochemicals. Grades: Purified. CAS No. 137339-65-2. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Thrombin receptor agonist peptide trifluoroacetate salt | Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor. Synonyms: TRAP-14. Grades: ≥95%. Molecular formula: C81H118N20O23·xCF3COOH. Mole weight: 1739.92. | |
| Thrombin receptor peptide ligand trifluoroacetate salt | Thrombin receptor peptide ligand acts as an antagonist of the thrombin receptor. It can inhibits α-thrombin and platelet aggregation induced by thrombin receptor activating peptide (TRAP) in vitro. Synonyms: AFLARAA. Grades: ≥95%. Molecular formula: C33H54N10O8·xCF3COOH. Mole weight: 718.84. | |
| Bovine Prothrombin | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p...Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Human α-Thrombin | Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.21.5; Human Alpha Thrombin. CAS No. 9002-4-4. Pack Sizes: 50 U; 100 U. Product ID: HY-114164A. | |
| Human Prethrombin-1 | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature ...Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Human Prethrombin-2 | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature ...Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Human Prothrombin | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p...-Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Human Prothrombin Fragment 1 | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mat...1 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Human Prothrombin Fragment 1.2 | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the ma... (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Human Prothrombin Fragment 2 | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mat...1 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Mouse Prothrombin | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p...-Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20 | |
| Native Bovine Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. Applications: Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of ...Ia; E thrombin; β-thrombin; γ-thrombin. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Form: Type I, Lyophilized from saline sodium Citrate buffer, pH 6.5; Type II, buffered aqueous solution, In 0.05 M phosphate buffer, pH 7.0. Source: Bovine plasma. Species: Bovine. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0698. | |
| Native Human Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Lyophilized powder containing sucrose, sodium chloride and tris. thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. Group: Enzymes. Synonyms: thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thromb. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Form: lyophilized powder. Source: Human plasma. Species: Human. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0699. | |
| Native Porcine Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Applications: Diagnostic controls, calibrators & standards; immunoassays; testing/assay validation; life science; manufacturing; coagulation/anemia. Group: Enzymes. Synonyms: thrombin; alpha Subunit Thrombin. Thrombin. Mole weight: 362 kDa. Activity: > 1,000 NIH U/mg. Stability: 2 years. Storage: Store at -20°C. Form: Liquid in 0.05 M sodium Citrate, 0.2 M NaCl, 0.1% PEG-8,000, pH 6.5. Source: Porcine Plasma. Species: Porcine. thrombin; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin; alpha Subunit Thrombin. Cat No: NATE-0970. | |
| Native Rabbit Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. The nih assay procedure uses 0.2 ml diluted plasma (1:1 with saline) as a substrate and 0.1 ml of thrombin sample (stabilized in a 1% buffered albumin solution) based on a modification of the method of biggs. only clotting times in the range of 15-25 seconds are used for determining thrombin concentrations. activity is expressed in nih units obtained by direct comparison to a nih thrombin reference standard. Group: Enzymes. Synonyms: thrombin; 9002-04-4; EC 3.4.21. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Source: Rabbit plasma. Species: Rabbit. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0700. | |
| Native Rat Thrombin | Thrombin is a serine protease that in humans is encoded by the F2 gene. Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the reduction of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. Thrombin is the final coagulation protease in regard to hemostasis, promoting both procoagulant and anticoagulant effects. Applications: Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. thrombin has been used in a study to investigate activation of equine platelet-rich plasma. Group: Enzymes. Synonyms: thrombin; 9002-04-4; EC 3.4.21.5; fibrin. Enzyme Commission Number: EC 3.4.21.5. CAS No. 9002-4-4. Thrombin. Activity: 600-2,000 NIH units/mg protein (biuret) or > 2,000 NIH units/mg protein (E1%/280 = 19.5); > 125 NIH units/mg protein (biuret). Form: lyophilized powder. Source: Rat plasma. Species: Rat. thrombin; 9002-04-4; EC 3.4.21.5; fibrinogenase; thrombase; thrombofort; topical; thrombin-C; tropostasin; activated blood-coagulation factor II; blood-coagulation factor IIa; factor IIa; E thrombin; β-thrombin; γ-thrombin. Cat No: NATE-0701. | |
| 1,2,3,4-Tetradehydro Argatroban | 1,2,3,4-Tetrahydro Argatroban is a metabolite of Argatroban (A769000); a synthetic thrombin inhibitor and antithrombotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 951130-92-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C23H32N6O5S. US Biological Life Sciences. | Worldwide |
| 1,2,3,4-Tetrahydro Argatroban-d8 | 1,2,3,4-Tetrahydro Argatroban-d8 is the isotope labelled analog of 1,2,3,4-Tetrahydro Argatroban (T293055); a metabolite of Argatroban (A769000) which is a synthetic thrombin inhibitor and antithrombotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H24D8N6O5S, Molecular Weight: 512.65. US Biological Life Sciences. | Worldwide |
| 1-Benzoyl-3-piperidinone | 1-Benzoyl-3-piperidinone is synthesized from 3-Hydroxypiperidine. 3-Hydroxypiperidine is used as a reagent to synthesize trisubstituted ureas, compounds that act as thrombin receptor (PAR-1) antagonists. 3-Hydroxypiperidine is also a metabolite of Piperidine, Piperidine is an organic heterocyclic amine widely used as building block and reagent in the synthesis of organic compounds including pharmaceuticals. Group: Biochemicals. Grades: Highly Purified. CAS No. 67452-85-1. Pack Sizes: 500mg, 5g. Molecular Formula: C12H13NO2, Molecular Weight: 203.24. US Biological Life Sciences. | Worldwide |
| 2-[[[4- (Aminoiminomethyl) phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride | 2-[[[4- (Aminoiminomethyl) phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride is derived from Dabigatran (D100090), which is a non-peptide, direct thrombin inhibior and anti-thrombotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1422435-39-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C19H21N5O2; (HCl), Molecular Weight: 351.403645999999. US Biological Life Sciences. | Worldwide |
| 2- [ [ [4- [ (Z) -Amino [ [ (hexyloxy) carbonyl] imino] methyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazole-5-carboxylic Acid | 2- [ [ [4- [ (Z) -Amino [ [ (hexyloxy) carbonyl] imino] methyl] phenyl] amino] methyl] -1-methyl-1H-benzimidazole-5-carboxylic Acid is a degradation product of Dabigatran (D100090). which is a drug that is a nonpeptide, direct thrombin inhibitor and an antithrombotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 1848337-06-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C24H29N5O4, Molecular Weight: 451.52. US Biological Life Sciences. | Worldwide |
| 2-Amino-4,4-dimethylpentanoic Acid | 2-Amino-4,4-dimethylpentanoic Acid is an unnatural amino acid used in vitro biological study of highly modified macrocyclic peptide analogs that act as tight binding inhibitors of thrombin. Group: Biochemicals. Grades: Highly Purified. CAS No. 106247-35-2. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H15NO2, Molecular Weight: 145.199999999999. US Biological Life Sciences. | Worldwide |
| 2-Chloromethyl Dabigatran Etexilate | 2-Chloromethyl Dabigatran Etexilate is an impurity of Dabigatran Etexilate (D100150) a nonpeptide, direct thrombin inhibitor. Antithrombotic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C35H42ClN7O5, Molecular Weight: 676.2. US Biological Life Sciences. | Worldwide |
| 2-Heptyl Chloroformate | 2-Heptyl Chloroformate is a potential impurity in the synthesis of Dabigatran Etexilate Mesylate (D100150); a nonpeptide and direct thrombin inhibitor. Antithrombotic. Group: Biochemicals. Grades: Highly Purified. CAS No. 290819-03-3. Pack Sizes: 1g, 2.5g. Molecular Formula: C8H15ClO2, Molecular Weight: 178.66. US Biological Life Sciences. | Worldwide |
| (2R,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid | (2R,4R)-1-Boc-4-fluoro-2-pyrrolidinecarboxylic Acid is an intermediate used to prepare amino acid benzylamide derivatives as thrombin inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 681128-51-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C10H16FNO4, Molecular Weight: 233.24. US Biological Life Sciences. | Worldwide |
| (2R,4R)-4-methyl-1-(N2-((3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-Nw-nitro-L-arginyl)piperidine-2-carboxylic acid | (2R,4R)-4-methyl-1-(N2-((3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-Nw-nitro-L-arginyl)piperidine-2-carboxylic acid is an impurity of Argatroban, a synthetic thrombin inhibitor and antithrombotic agent. Synonyms: Argatroban Impurity F. CAS No. 1448301-07-2. Molecular formula: C23H35N7O7S. Mole weight: 553.63. | |
| (2S,4S)-Argatroban | Synthetic thrombin inhibitor. Antithrombotic. Group: Biochemicals. Alternative Names: (2S, 4S) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3-methyl-8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: Highly Purified. CAS No. 189264-03-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| (2S,4S)-Argatroban | Synthetic thrombin inhibitor. Synonyms: (2S,4S)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: > 95%. CAS No. 189264-03-7. Molecular formula: C23H36N6O5S. Mole weight: 508.64. | |
| [3-20} Bivalirudin TFA Salt | [3-20} Bivalirudin is an impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C84H122N22O31 x(C2HF3O2). US Biological Life Sciences. | Worldwide |
| 3-Acetylbenzoyl Chloride | 3-Acetylbenzoyl Chloride is used in the synthesis of aminimdes as potential CNS acting agents. Also, it is an intermediate used in the synthesis of 3-[ (Dimethylamino) carbonyl]phenol (D461635), which can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin. Group: Biochemicals. Grades: Highly Purified. CAS No. 31076-85-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H7ClO2, Molecular Weight: 182.6. US Biological Life Sciences. | Worldwide |
| 3-Bromo-2-oxo-1(2H)-pyrazineacetic Acid Ethyl Ester | 3-Bromo-2-oxo-1(2H)-pyrazineacetic Acid Ethyl Ester is used in the synthesis of potent and selective proline- and pyrazinone-based macrocyclic thrombin inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 267876-34-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H9BrN2O3, Molecular Weight: 261.07. US Biological Life Sciences. | Worldwide |
| 5- (4-Methoxyphenoxy) pentanoic Acid | 5- (4-Methoxyphenoxy) pentanoic Acid is a reactant used in the preparation of PPV derivatives and precursors of thrombin and tryptase. Group: Biochemicals. Grades: Highly Purified. CAS No. 374565-57-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Aaf-Arg-OH HCl | Aaf-Arg-OH HCl, a substrate of carboxypeptidase B-type enzymes, has been used to determine the activation of TAFI (thrombin activatable fibrinolysis inhibitor, carboxypeptidase U) by thrombin and thrombin-thrombomodulin. Synonyms: N-(4-Methoxyphenylazoformyl)-Arg-OH HCl; N2-{[(4-Methoxyphenyl)diazenyl]carbonyl}-L-arginine hydrochloride (1:1); L-Arginine, N2-[[2-(4-methoxyphenyl)diazenyl]carbonyl]-, hydrochloride (1:1). Grades: ≥95% by HPLC. CAS No. 442158-31-8. Molecular formula: C14H20N6O4.HCl. Mole weight: 372.81. | |
| Abelacimab | Abelacimab (MAA868) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab can be used in thromboembolic disease studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MAA868. CAS No. 2098724-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99415. | |
| AEBSF HCl | AEBSF is a water-soluble, irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Synonyms: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride; AEBSF hydrochloride; AEBSF. Grades: 98%. CAS No. 30827-99-7. Molecular formula: C8H11ClFNO2S. Mole weight: 239.69. | |
| AEBSF hydrochloride | AEBSF hydrochloride is an irreversible inhibitor of serine proteases , such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Uses: Scientific research. Group: Signaling pathways. CAS No. 30827-99-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-12821. | |
| Aggreceride A | It is produced by the strain of Streptomyces sp. OM-3209. Aggreceride had no antibacterial activity. Aggreceride A of 50 ?/ml inhibited thrombin-induced platelet aggregation of 92%. Aggreceride A of 25 ?/ml inhibited thrombin-induced platelet aggregation of 81%. Synonyms: S3L0ID00Y9; 2,3-Dihydroxypropyl 12-methyltetradecanoate; Tetradecanoic acid, 12-methyl-, 2,3-dihydroxypropyl ester; CTK4E0886; DTXSID50172766; (S)-12-Methyltetradecanoic acid (R)-2,3-dihydroxypropyl ester; Tetradecanoic acid,12-methyl-, (2R)-2,3-dihydroxypropyl ester, (12S)-. CAS No. 19207-26-2. Molecular formula: C18H36O4. Mole weight: 316.47. | |
| (Ala1)-PAR-4 (1-6) (mouse) | (Ala1)-PAR-4 (1-6) (mouse) is a peptide used in compound to study the role of PAR-4 (Prostate Apoptosis Response 4) in mice. It is specifically designed to mimic the first six amino acids of mouse PAR-4 and is utilized to investigate its function and potential therapeutic targets in diseases such as cancer and apoptosis-related disorders. Synonyms: (Ala1)-Thrombin Receptor-Like 3 (1-6) (mouse); H-AYPGKF-OH; L-alanyl-L-tyrosyl-L-prolyl-glycyl-L-lysyl-L-phenylalanine; (Ala1)-Proteinase Activated Receptor 4 (1-6) (Mouse); (Ala1)-Coagulation Factor II Receptor-Like 3 (1-6) (Mouse). Grades: ≥95%. CAS No. 380900-00-5. Molecular formula: C34H47N7O8. Mole weight: 681.78. | |
| Antibiotic Sch 38519 | Sch 38519 is an isochromanequinone, structurally related to lactoquinomycin. Sch 38519 inhibits thrombin-induced aggregation of human platelets and is active against Gram +ve and Gram -ve bacteria. Group: Biochemicals. Grades: Highly Purified. CAS No. 114970-20-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Antibiotic TS 155-2 | Antibiotic TS155-2 is a macrocyclic lactone related to hygrolidin but produced by a different Streptomyces species. Antibiotic TS155-2 is reported to be an inhibitor of calcium entry into the cell induced by thrombin stimulation. With the exception of the original patent suggesting hypotensive, anti-platelet, anti-ischaemic and anti-inflammatory activity, no literature investigation of TS155-2 is available. Group: Biochemicals. Grades: Highly Purified. CAS No. 303009-07-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Argatroban | Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Uses: Antithrombins; platelet aggregation inhibitors. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: >98%. CAS No. 74863-84-6. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban | Argatroban (MD-805) is a direct, selective thrombin inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 74863-84-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0375. | |
| Argatroban ( (2R, 4R) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3-methyl-8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid, Argipidine, MQPA) | Synthetic thrombin inhibitor. Group: Biochemicals. Alternative Names: (2R, 4R) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3-methyl-8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid; Argipidine; MQPA. Grades: Highly Purified. CAS No. 74863-84-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Argatroban-d3 | Labeled synthetic thrombin inhibitor. Antithrombotic. Group: Biochemicals. Alternative Names: (2R, 4R) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3- (methyl-d3) -8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid; Argipidine-d3; MQPA-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Argatroban (L,2R,4S)-isomer | Argatroban (L,2R,4S)-isomer is an impurity of Argatroban, a synthetic thrombin inhibitor and antithrombotic agent. Synonyms: (2R,4S)-4-methyl-1-(((3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonyl)-L-arginyl)piperidine-2-carboxylic acid; (2R,4S)-1-((2S)-5-Guanidino-2-(3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamido)pentanoyl)-4-methylpiperidine-2-carboxylic Acid; Argatroban (L,2R,4S)-Isomer (Mixture of Diastereomers). CAS No. 189264-04-8. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban monohydrate | Argatroban is an anticoagulant that acts as a potent, seletive, univalent direct inhibitor of thrombin. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). Synonyms: (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid hydrate; MCI-9038; MCI 9038; MCI9038; MD805; MD-805; MD 805; DK-7419; DK 7419; DK7419; GN1600; GN-1600; GN 1600; MMTQAP; MPQA; OM 805; Slonnon; Argipidine; Argatroban monohydrate. Grades: 98%. CAS No. 141396-28-3. Molecular formula: C23H38N6O6S. Mole weight: 526.65. | |
| Argatroban monohydrate | Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MD-805 monohydrate; MCI-9038 monohydrate; Argipidine monohydrate. CAS No. 141396-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0375A. | |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Synonyms: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grades: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
| Arg-Gly-Asp-Ser acetate | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Molecular formula: C17H31N7O10. Mole weight: 493.47. | |
| AT-1459 | AT-1459 is a novel, direct thrombin inhibitor with antithrombotic efficacy (Ki = 4.9 nM). Uses: Thrombin inhibitor. Synonyms: AT-1459; AT 1459; AT1459; UNII-JWP323ABVS; Butanoic acid, 4-[[(3S)?-1-[2-[(2S)?-2-[2-[6-(aminoiminomethyl)?-1-ethyl-1H-indol-2-yl]?ethyl]?-1-pyrrolidinyl]?-2-oxoethyl]?hexahydro-2-oxo-1H-azepin-3-yl]?amino]?-. Grades: ≥95%. CAS No. 294658-50-7. Molecular formula: C29H42N6O4. Mole weight: 538.32. | |
| Atopaxar | Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E5555; ER-172594-00. CAS No. 751475-53-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-18200. | |
| Atopaxar | Atopaxar is a Protease-activated receptor-1 (PAR-1) inhibitor. It can inhibit the binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP) to PAR-1 with IC50 value of 0.019μM. Atopaxar exhibits potent inhibitory effects on human platelet aggregation induced by thrombin and TRAP with IC50 values of 0.064 and 0.031μM. It may become a therapeutic option for atherothrombotic disease. In May 2012, Phase-II for Acute coronary syndromes in European Union was discontinued. Uses: Acute coronary syndromes. Synonyms: E5555; E-5555; E 5555; ER-172594-00; ER172594-00; ER 172594-00; Atopaxar;1-(3-(tert-butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoisoindolin-2-yl)ethan-1-one;474550-69-1(hydrobromide). Grades: 98%. CAS No. 751475-53-3. Molecular formula: C29H38FN3O5. Mole weight: 527.64. | |
| AZD-0837 | AZD0837 is an oral direct thrombin inhibitor currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial fibrillation. Uses: Potassium channel antagonist. Synonyms: AZD0837; AZD-0837; AZD 0837; Atecegatran metoxil; Atecegatran fexenetil.1-((2R)-(3-chloro-5- (difluoromethoxy) phenyl) hydroxyacetyl) -N- ( (4- (imino (methoxyamino) methyl) phenyl) methyl) -, (2S) -2-Azetidinecarboxamide; (S) -1- ( (R) -2- (3-chloro-5- (difluoromethoxy) phenyl) -2-hydroxyacetyl) -N- (4- (N-methoxycarbamimidoyl) benzyl) azetidine-2-carboxamide. Grades: ≥95%. CAS No. 433937-93-0. Molecular formula: C22H23ClF2N4O5. Mole weight: 496.89. | |
| BAY-386 | BAY-386 is a novel PAR1 receptor inhibitor that suppresses activation of thrombin and platelet. It is orally active, and has the potential to treat coagulation disorders such as arterial thrombosis. Uses: The potential treatment of coagulation disorders. Synonyms: BAY 386; BAY386. CAS No. 1256941-06-6. Molecular formula: C22H25F3N4O5S. Mole weight: 514.52. | |
| Benzamidine hydrochloride | Benzamidine hydrochloride is a trypsin-like serine proteases with K i s of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1670-14-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W018781. | |
| Benzamidine hydrochloride | Benzamidine is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Kis = 35, 350, and 220 μM, respectively). Benzamidine inhibits the autoactivation of human blood coagulation factor VII, useful as a tool for studying the interactions between this and other relevant growth factors. Uses: Serine proteinase inhibitors. Synonyms: Benzenecarboximidamide, hydrochloride (1:1); Benzamidine, monohydrochloride; Benzenecarboximidamide, monohydrochloride; Amidinobenzene hydrochloride; Benzamidinium chloride; Benzimidamide hydrochloride. Grades: ≥98%. CAS No. 1670-14-0. Molecular formula: C7H8N2.HCl. Mole weight: 156.61. | |
| Benzamidine hydrochloride hydrate | Benzamidine (Benzenecarboximidamide) hydrochloride hydrate is a reversible competitive trypsin-like serine proteases inhibitor with K i s of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Benzenecarboximidamide hydrochloride hydrate. CAS No. 206752-36-5. Pack Sizes: 5 g; 10 g. Product ID: HY-W087937. | |
| Biotinylated Transglutaminase from Human, Recombinant | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. Applications: Recombinant human transglutaminase is a homodimer (a2) composed of two chains held together by non covalent bonds. after activation of the zymogen by thrombin and ca2+ to its active form (a*2, factor xiiia), factor xiiia catalyzes the formation of covalent bridges (ε-(γ-glutamyl) lysine bonds) between fibrin units to increase the elasticity of the clot network. the resulting cross-linked fibrin is insoluble and resistant to lysis. Group: Enzymes. Synonyms: transglutamina... Lorand et al., Anal. Biochem. 44 (221-231). Appearance: Liquid. Storage: Store working aliquots at ≤ - 20°C. Avoid repeated freezing and thawing. Form: The transglutaminase is formulated in 10 mM Sodium Phosphate pH 8.0, 15 mM NaCl. Sample contains 50% glycerol. hFXIII is a Ca2+-dependent enzyme. Source: Insect cells. Species: Human. transglutaminase; EC 2.3.2.13; 80146-85-6; transglutaminase; Factor XIIIa; fibrinoligase; fibrin stabilizing factor; glutaminylpeptide γ-glutamyltransferase; polyamine transglutaminase; tissue transglutaminase; R-glutaminyl-peptide:amine γ-glutamyl transferase; protein-glutamine γ-glutamyltransferase; TG1. Pack: 50 | |
| Bivalirudin | Bivalirudin, a peptide anticoagulant, is a direct thrombin inhibitor for anticoagulation in the setting of invasive cardiology, particularly percutaneous coronary intervention [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 128270-60-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1929. | |
| Bivalirudin | Bivalirudin is a specific and reversible direct thrombin inhibitor (DTI). It is a synthetic congener of the naturally occurring drug hirudin. It is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. It is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. It has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore, it has a predictable antithrombotic response. It does not require a binding cofactor such as antithrombin and does not activate platelets. Synonyms: Hirulog; Hirulog I; Angiomax; Hirulog-1; Hirulog1; Hirulog 1; BG8967; BG 8967; BG-8967; LS-172701; LS172701; LS 172701. Grades: > 95%. CAS No. 128270-60-0. Molecular formula: C98H138N24O33. Mole weight: 2180.32. | |
| Bivalirudin TFA | Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin. Uses: Scientific research. Group: Peptides. CAS No. 1191386-55-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15664. | |
| Bivalirudin Trifluoroacetate | Bivalirudin is a specific and reversible bivalent direct thrombin inhibitor. Bivalirudin specifically binds to both the catalytic site and to the anion-binding exosite of circulating and clot-bound thrombin. Synonyms: Bivalirudin TFA; Bivalirudin TFA salt; H-D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH. Grades: >98%. Molecular formula: C100H138DF3N24O35. Mole weight: 2295.32. | |
| Bmy 42393 | BMY-42393 is a selective platelet aggregation inhibitor. It is also a prostacyclin partial agonist that inhibited ADP, collagen and thrombin-induced platelet aggregation with IC50 value range from 0.3 to 2.0 mM. BMY-42393 can stimulate platelet adenylate cyclase with EC50 value of 25 nM. BMY 42393 can also inhibit thrombin-induced elevation of intracellular free calcium. Research for the treatment of Hyperlipidaemia was discontinued. Uses: Hyperlipidaemia. Synonyms: BMY-42393; BMY 42393; BMY42393. SCHEMBL675089; AC1L304B; CHEMBL117835;2-[3-[2-(4,5-diphenyl-1,3-oxazol-2-yl)ethyl]phenoxy]acetic acid. Grades: 98%. CAS No. 136451-58-6. Molecular formula: C25H21NO4. Mole weight: 399.45. | |
| BOC-VAL-PRO-ARG-MCA TFA salt | BOC-VAL-PRO-ARG-MCA is a specific, highly fluorogenic substrate for thrombin and the thrombin-staphylocoagulase complex. Synonyms: Boc-Val-Pro-Arg-4-methylcoumaryl-7-amide TFA salt; Boc-Val-Pro-Arg-4-methyl-7-coumarylamide TFA salt. Molecular formula: C33H46F3N7O9. Mole weight: 741.76. | |
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