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| Product | Description | |
|---|---|---|
| Thyrotropin | Thyroid-stimulating hormone is a pituitary hormone that stimulates the thyroid gland to produce thyroxine. Synonyms: TSH. Grade: 95%. CAS No. 9002-71-5. Molecular formula: C56H102Ir5O10. |  |
| Thyrotropin | Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism [1] [2] [3] [4] [13]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSH; Pretiron. CAS No. 9002-71-5. Pack Sizes: 5 μg; 10 μg. Product ID: HY-107916. |  |
| Thyrotropin-Releasing Hormone (TRH), Free Acid | Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) is a physiological metabolite of Thyrotropin-Releasing Hormone. Uses: Scientific research. Group: Peptides. Alternative Names: TRH-OH. CAS No. 24769-58-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1529. | |
| Acid-TRH | Acid-TRH. Synonyms: L-Proline, 5-oxo-L-prolyl-L-histidyl-; Proline, 1-[N-(5-oxo-L-prolyl)-L-histidyl]-, L-; L-Proline, 1-[N-(5-oxo-L-prolyl)-L-histidyl]-; 5-Oxo-L-prolyl-L-histidyl-L-proline; L-Pyroglutamyl-L-histidyl-L-proline; Deamino-thyrotropin releasing hormone; Thyrotropin-releasing hormone free acid; Deamido-thyrotropin-releasing factor; TRH-OH; Deamidated TRH; Deamido-TRH; Acid thyroliberin. Grade: >95%. CAS No. 24769-58-2. Molecular formula: C16H21N5O5. Mole weight: 363.37. | |
| D3-βArr | D3-βArr is a positive allosteric modulator of thyrotropin (TSH) receptor. D3-βArr does not activate Beta-Arr 1 translocation to the glucagon-like peptide 1 receptor (GLP-1R) in CHO-K1-GLP1R-Beta Arrestin 1 cells. Synonyms: NCGC00379308; D3-betaArr. CAS No. 662164-09-2. Molecular formula: C20H23N5. Mole weight: 333.4. | |
| glutaminyl-peptide cyclotransferase | Involved in the formation of thyrotropin-releasing hormone and other biologically active peptides containing N-terminal pyroglutamyl residues. The enzyme from papaya also acts on glutaminyl-tRNA. Group: Enzymes. Synonyms: glutaminyl-tRNA cyclotransferase; glutaminyl cyclase; glutaminyl-transfer ribonucleate cyclotransferase. Enzyme Commission Number: EC 2.3.2.5. CAS No. 37257-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2305; glutaminyl-peptide cyclotransferase; EC 2.3.2.5; 37257-21-9; glutaminyl-tRNA cyclotransferase; glutaminyl cyclase; glutaminyl-transfer ribonucleate cyclotransferase. Cat No: EXWM-2305. |  |
| (His(3-Me)2)-TRH | It is a TRH analog that has improved in vitro and in vivo biostability. Synonyms: (His(π-Me)2)-TRH; (His(3-Me)2)-TRH; Pyroglutamyl-3-methylhistidyl-prolinamide; 3-Mehis-trh; 3-Methylhistidine-trh; 3-Me-Trh; 3-Me-His(2)trh; Pglu-3-Me-his-pro-NH2; 3-Methyl-thyrotropin-releasing hormone; 3-Methyl-L-histidyl-N-{[(2S)-5-oxo-2-pyrrolidinyl]carbonyl}-L-prolinamide. Grade: 95%. CAS No. 34367-54-9. Molecular formula: C17H24N6O4. Mole weight: 376.41. | |
| JKC 363 | JKC 363 has been found to be a melanocortin MC4 receptor antagonist and could suppress the release of thyrotropin-releasing hormone (TRH). Synonyms: (Deamino-Cys11,D-2-Nal14,Cys18)-β-MSH (11-22) amide; JKC363; JKC-363; 3-Mercaptopropionyl-Glu-His-D-2-Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 (Disulfide bond); deamino-Cys-Glu-His-D-2Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asn-OH (Disulfide bridge: Cys1-Cys8); deamino-cysteinyl-L-alpha-glutamyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-L-asparagine (1->8)-disulfide; beta-MSH (11-12)-amide, mercaptopropionic acid(11)-naphthylalanyl(14)-cysteinyl(18)-aspartyl(22)-; beta-MSH (11-22)-amide, Mrp(11)-Nal(14)-Cys(18)-Asp(22)-; [Deamino-Cys11,β-(2-Naphthyl)-D-Ala14,Cys18]-β-Melanocyte Stimulating Hormone Amide Fragment 11-22. Grade: ≥95% by HPLC. CAS No. 436083-30-6. Molecular formula: C69H91N19O16S2. Mole weight: 1506.72. | |
| L-Pyroglutamyl-L-histidyl-L-prolinamide | L-Pyroglutamyl-L-histidyl-L-prolinamide. Group: Biochemicals. Alternative Names: Protirelin; Thyrotropin-Releasing Hormone. Grades: Highly Purified. CAS No. 24305-27-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C16H22N6O4. US Biological Life Sciences. |  Worldwide |
| MS438 | MS438 is a potent thyrotropin receptor ( TSHR ) agonist with an EC 50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 512840-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-114918. | |
| N-acetyl-β-glucosaminyl-glycoprotein 4-β-N-acetylgalactosaminyltransferase | The enzyme from human can transfer N-acetyl-D-galactosamine (GalNAc) to N-glycan and O-glycan substrates that have N-acetyl-D-glucosamine (GlcNAc) but not D-glucuronic acid (GlcUA) at their non-reducing end. The N-acetyl-β-D-glucosaminyl group is normally on a core oligosaccharide although benzyl glycosides have been used in enzyme-characterization experiments. Some glycohormones, e.g. lutropin and thyrotropin contain the N-glycan structure containing the N-acetyl-β-D-galactosaminyl-(1?4)-N-acetyl-β-D-glucosaminyl group. Group: Enzymes. Synonyms: β1,4-N-acetylgalactosaminyltransferase III; β4GalNAc-T3; β1,4-N-acetylgalactosaminylt. Enzyme Commission Number: EC 2.4.1.244. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2473; N-acetyl-β-glucosaminyl-glycoprotein 4-β-N-acetylgalactosaminyltransferase; EC 2.4.1.244; β1,4-N-acetylgalactosaminyltransferase III; β4GalNAc-T3; β1,4-N-acetylgalactosaminyltransferase IV; β4GalNAc-T4; UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group β-1,4-N-acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:N-acetyl-β-D-glucosaminyl-group 4-β-N-acetylgalactosaminyltransferase. Cat No: EXWM-2473. | |
| Octreotide Acetate | Octreotide acetate is a long-acting octapeptide with pharmacologic actions similars to the natural hormone somatostatin. It is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was approved as an injectable depot formulation used for acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors. It is a gastric antisecretory agent andcould inhibit the secretion of insulin and glucagon. It reduces production of IGF-1 and IGF-2 by the liver by modulation of growth-hormone secretion from the pituitary gland. It decreased the urinary excretion of uric acid as well as the plasma concentrations of glucagon and insulin. It decreased the urinary excretion of sodium and chloride without significiant influence on creatinine clearance, while the concentrations of lactic acid, pyruvic acid in blood, and cyclic AMP in plasma were not changed. It was first synthesized in 1979 by the chemist Wilfried Bauer and was developed by Novartis Pharmaceuticals. Uses: Antineoplastic agents, hormonal. Synonyms: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, acetate (1:x); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol.xCH3CO2H (Disulfide Bridge between Cys2-Cys7); D-phen | |
| Protirelin | Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone; TRH. CAS No. 24305-27-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0002. | |
| Protirelin | Protirelin. Uses: For analytical and research use. Group: Api standards; european pharmacopoeia (ph. eur.); pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: Thyrotropic hormone-releasing factor, L-Pyroglutamyl-L-histidyl-L-proline amide, Lopremone, Synthetic thyrotropin-releasing hormone, Antepan, Synthetic thyrotropin-releasing factor, TRF, Thyrotropic releasing hormone, Stimu TSH, Thyrotropin-releasing hormone, Synthetic TRH, L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2, 83: PN: US20090175821 PAGE: 403 claimed protein, TSH-RF, Rifotironin, Thyroliberin, Prem, Thyrotropin-releasing factor (8CI), Synthetic TSH-releasing hormone, TRH, Protirelin, Thyrefact, Thyrotropic-releasing factor, FDA 1725, Synthetic TSH-releasing factor, Thypinone, L-Pyroglutamyl-L-histidyl-L-prolinamide, Synthetic TRF,Protirelin, Relefact TRH, Ro 8-6270/9, 5-Oxo-l-prolyl-l-histidyl-l-prolinamide, Abbott 38579, Rifathyroin, Thyroid-stimulating hormone-releasing factor, TSH-releasing hormone, Thyroid releasing hormone, 252: PN: WO2010033207 SEQID: 378 claimed protein, TSH-releasing factor, Thyrotropic hormone-releasing hormone. CAS No. 24305-27-9. IUPAC Name: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. Molecular formula: C16H22N6O4. Mole weight: 362.38. Catalog: APS24305279. SMILES: NC(=O)[C@@H]1CCCN1C(=O)[C@H]( |  |
| Protirelin acetate | Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone acetate; TRH acetate. CAS No. 120876-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P0002A. | |
| pyroglutamyl-peptidase II | Highly specific for thyrotropin releasing hormone (pyroglutamyl-histidyl-prolylamide). Will not cleave the pyroglutamyl-histidyl bond of luteinizing hormone releasing hormone. Found in serum and brain. Inhibited by metal chelators. In peptidase family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: thyroliberinase; pyroglutamyl aminopeptidase II; thyrotropin-releasing factor pyroglutamate aminopeptidase; pyroglutamate aminopeptidase II; pyroglutamyl peptidase II; thyroliberin-hydrolyzing pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading peptidase; TRH aminopeptidase. Enzyme Commission Number: EC 3.4.19.6. CAS No. 60063-88-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4090; pyroglutamyl-peptidase II; EC 3.4.19.6; 60063-88-9; thyroliberinase; pyroglutamyl aminopeptidase II; thyrotropin-releasing factor pyroglutamate aminopeptidase; pyroglutamate aminopeptidase II; pyroglutamyl peptidase II; thyroliberin-hydrolyzing pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading peptidase; TRH aminopeptidase. Cat No: EXWM-4090. | |
| Taltirelin | Taltirelin is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Synonyms: N-[[(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-L-prolinamide; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide; (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide; Ceredist; TA 0910; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide. Grade: >98%. CAS No. 103300-74-9. Molecular formula: C17H23N7O5. Mole weight: 405.41. | |
| Taltirelin | Taltirelin (TA-0910) is an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist ( IC 50 at 910 nM). Taltirelin can cross the blood-brain barrier. Taltirelin stimulates an increase in cytosolic Ca 2+ concentration (Ca 2+ release) with an EC 50 value of 36 nM. Taltirelin increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons treated with MPP+ (HY-W008719) or Rotenone (HY-B1756). Taltirelin has neuroprotective effects in both cellular and animal models of Parkinson's disease. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-0910. CAS No. 103300-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0596. | |
| Taltirelin acetate | Taltirelin acetate (TA-0910) is an acetate form of Taltirelin (TA-0910). Taltirelin (TA-0910) is an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist ( IC 50 at 910 nM). Taltirelin can cross the blood-brain barrier. Taltirelin stimulates an increase in cytosolic Ca 2+ concentration (Ca 2+ release) with an EC 50 value of 36 nM. Taltirelin increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons treated with MPP+ (HY-W008719) or Rotenone (HY-B1756). Taltirelin has neuroprotective effects in both cellular and animal models of Parkinson's disease. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-0910 acetate. CAS No. 1549593-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0596A. | |
| Taltirelin Hydrate | Taltirelin hydrate is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Uses: Nootropic agents. Synonyms: N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide tetrahydrate; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide tetrahydrate; Ceredist tetrahydrate; TA 0910 tetrahydrate; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide tetrahydrate; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide tetrahydrate. Grade: ≥95%. CAS No. 201677-75-0. Molecular formula: C17H31N7O9. Mole weight: 477.46. | |
| Thyroid-stimulating hormone-releasing hormone | Thyroid-stimulating hormone-releasing hormone is a constitution-stimulating hormone produced by hypothalamic neurons. It can stimulate the anterior pituitary to release thyroid-stimulating hormone and prolactin. Uses: Hormones. Synonyms: Protirelin; TSH-RF; pGlu-His-Pro-NH2; {pGLU}HP-NH2; Thyroliberin; L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-; 5-Oxo-L-prolyl-L-histidyl-L-prolinamide; Thyrotropin-releasing factor; (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2; L-Pyroglutamyl-L-histidyl-L-prolinamide; Abbott 38579; Antepan; FDA 1725; Lopremone; Prem; Relefact TRH; Rifathyroin; Rifotironin; Ro 8-6270/9; Stimu TSH; Synthetic thyrotropin-releasing factor; Synthetic thyrotropin-releasing hormone; Synthetic TRF; Synthetic TRH; Thypinone; Thyrefact; Thyroid releasing hormone; Thyroid-stimulating hormone-releasing factor; TRF; TRH; TSH-releasing factor; TSH-releasing hormone. Grade: 95%. CAS No. 24305-27-9. Molecular formula: C16H22N6O4. Mole weight: 362.38. | |
| Thyroliberin acetate salt | Thyroliberin acetate salt is a highly conserved neuropeptide that stimulates the release of thyrotropin and prolactin and plays a hormonal role in controlling thyroid-stimulating hormone (TSH) levels and neuromodulatory functions. Synonyms: Lopremone Acetate; TRH Acetate; Thyroliberin Acetate; TRF Acetate; pGlu-His-Pro-NH2 Acetate; Synthetic thyrotropin-releasing hormone Acetate; Protirelin acetate; Protirelin monoacetate; H-Pyr-His-Pro-NH2.CH3CO2H; Pyr-HP-NH2.CH3CO2H; L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, acetate (1:1); L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, monoacetate; Thyrotropin-releasing factor (pig), monoacetate; Pyroglutamylhistidylprolinamide acetate; Thyrotropin-releasing hormone acetate; L-pyroglutamyl-L-histidyl-L-prolinamide acetic acid. Grade: ≥95%. CAS No. 25575-91-1. Molecular formula: C18H26N6O6. Mole weight: 422.44. | |
| Trh-gly | Trh-gly. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GLP-HIS-PRO-GLY;PYR-HIS-PRO-GLY-OH;PYR-HIS-PRO-GLY;PE-H-P-G;THYROTROPIN-RELEASING HORMONE-GLY;TRH-GLY;pglu-his-pro-gly. Product Category: Heterocyclic Organic Compound. CAS No. 85344-77-0. Molecular formula: C18H24N6O6. Mole weight: 420.42. Purity: 0.96. IUPACName: 2-[[1-[3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid. Canonical SMILES: C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)NCC(=O)O. Density: 1.461g/cm³. Product ID: ACM85344770. Alfa Chemistry ISO 9001:2015 Certified. Categories: Triglyceride. |  |
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