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| Product | Description | |
|---|---|---|
| Thyrotropin | Thyroid-stimulating hormone is a pituitary hormone that stimulates the thyroid gland to produce thyroxine. Synonyms: TSH. Grades: 95%. CAS No. 9002-71-5. |  |
| Thyrotropin | Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism [1] [2] [3] [4] [13]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TSH; Pretiron. CAS No. 9002-71-5. Pack Sizes: 5 μg; 10 μg. Product ID: HY-107916. |  |
| Thyrotropin-Releasing Hormone (TRH), Free Acid | Synonyms: TRH; Thyroliberin; Thyrotropin-releasing hormone; Prothyroliberin. Grades: >95%. CAS No. 24769-58-2. Molecular formula: C16H21N5O5. Mole weight: 363.37. | |
| Thyrotropin-Releasing Hormone (TRH), Free Acid | Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) is a physiological metabolite of Thyrotropin-Releasing Hormone. Uses: Scientific research. Group: Peptides. Alternative Names: TRH-OH. CAS No. 24769-58-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1529. | |
| glutaminyl-peptide cyclotransferase | Involved in the formation of thyrotropin-releasing hormone and other biologically active peptides containing N-terminal pyroglutamyl residues. The enzyme from papaya also acts on glutaminyl-tRNA. Group: Enzymes. Synonyms: glutaminyl-tRNA cyclotransferase; glutaminyl cyclase; glutaminyl-transfer ribonucleate cyclotransferase. Enzyme Commission Number: EC 2.3.2.5. CAS No. 37257-21-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2305; glutaminyl-peptide cyclotransferase; EC 2.3.2.5; 37257-21-9; glutaminyl-tRNA cyclotransferase; glutaminyl cyclase; glutaminyl-transfer ribonucleate cyclotransferase. Cat No: EXWM-2305. |  |
| JKC 363 | JKC 363 has been found to be a melanocortin MC4 receptor antagonist and could suppress the release of thyrotropin-releasing hormone (TRH). Synonyms: (Deamino-Cys11,D-2-Nal14,Cys18)-β-MSH (11-22) amide; JKC363; JKC-363; 3-Mercaptopropionyl-Glu-His-D-2-Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2 (Disulfide bond); deamino-Cys-Glu-His-D-2Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asn-OH (Disulfide bridge: Cys1-Cys8); deamino-cysteinyl-L-alpha-glutamyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-L-asparagine (1->8)-disulfide; beta-MSH (11-12)-amide, mercaptopropionic acid(11)-naphthylalanyl(14)-cysteinyl(18)-aspartyl(22)-; beta-MSH (11-22)-amide, Mrp(11)-Nal(14)-Cys(18)-Asp(22)-; [Deamino-Cys11,β-(2-Naphthyl)-D-Ala14,Cys18]-β-Melanocyte Stimulating Hormone Amide Fragment 11-22. Grades: ≥95% by HPLC. CAS No. 436083-30-6. Molecular formula: C69H91N19O16S2. Mole weight: 1506.72. | |
| L-Pyroglutamyl-L-histidyl-L-prolinamide | L-Pyroglutamyl-L-histidyl-L-prolinamide. Group: Biochemicals. Alternative Names: Protirelin; Thyrotropin-Releasing Hormone. Grades: Highly Purified. CAS No. 24305-27-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C16H22N6O4. US Biological Life Sciences. |  Worldwide |
| MK-771 | MK-771 is an analog of the Thyrotropin Releasing Hormone (TRH). It is a therapeutic agent. It may be useful in combating some of the withdrawal symptoms in opiate-dependent subjects. Uses: Mk-771 is a therapeutic agent. it may be useful in combating some of the withdrawal symptoms in opiate-dependent subjects. Synonyms: MK771; MK 771; (S)-3-((S)-3-(1H-imidazol-4-yl)-2-((S)-6-oxopiperidine-2-carboxamido)propanoyl)thiazolidine-4-carboxamide. Grades: 98%. CAS No. 66537-55-1. Molecular formula: C16H22N6O4S. Mole weight: 394.45. | |
| MS438 | MS438 is a potent thyrotropin receptor ( TSHR ) agonist with an EC 50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 512840-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-114918. | |
| N-acetyl-β-glucosaminyl-glycoprotein 4-β-N-acetylgalactosaminyltransferase | The enzyme from human can transfer N-acetyl-D-galactosamine (GalNAc) to N-glycan and O-glycan substrates that have N-acetyl-D-glucosamine (GlcNAc) but not D-glucuronic acid (GlcUA) at their non-reducing end. The N-acetyl-β-D-glucosaminyl group is normally on a core oligosaccharide although benzyl glycosides have been used in enzyme-characterization experiments. Some glycohormones, e.g. lutropin and thyrotropin contain the N-glycan structure containing the N-acetyl-β-D-galactosaminyl-(1?4)-N-acetyl-β-D-glucosaminyl group. Group: Enzymes. Synonyms: β1,4-N-acetylgalactosaminyltransferase III; β4GalNAc-T3; β1,4-N-acetylgalactosaminylt. Enzyme Commission Number: EC 2.4.1.244. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2473; N-acetyl-β-glucosaminyl-glycoprotein 4-β-N-acetylgalactosaminyltransferase; EC 2.4.1.244; β1,4-N-acetylgalactosaminyltransferase III; β4GalNAc-T3; β1,4-N-acetylgalactosaminyltransferase IV; β4GalNAc-T4; UDP-N-acetyl-D-galactosamine:N-acetyl-D-glucosaminyl-group β-1,4-N-acetylgalactosaminyltransferase; UDP-N-acetyl-D-galactosamine:N-acetyl-β-D-glucosaminyl-group 4-β-N-acetylgalactosaminyltransferase. Cat No: EXWM-2473. | |
| Protirelin | Protirelin is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone; TRH. CAS No. 24305-27-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P0002. | |
| Protirelin | Protirelin. Uses: For analytical and research use. Group: Api standards; european pharmacopoeia (ph. eur.); pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: Thyrotropic hormone-releasing factor, L-Pyroglutamyl-L-histidyl-L-proline amide, Lopremone, Synthetic thyrotropin-releasing hormone, Antepan, Synthetic thyrotropin-releasing factor, TRF, Thyrotropic releasing hormone, Stimu TSH, Thyrotropin-releasing hormone, Synthetic TRH, L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2, 83: PN: US20090175821 PAGE: 403 claimed protein, TSH-RF, Rifotironin, Thyroliberin, Prem, Thyrotropin-releasing factor (8CI), Synthetic TSH-releasing hormone, TRH, Protirelin, Thyrefact, Thyrotropic-releasing factor, FDA 1725, Synthetic TSH-releasing factor, Thypinone, L-Pyroglutamyl-L-histidyl-L-prolinamide, Synthetic TRF,Protirelin, Relefact TRH, Ro 8-6270/9, TSH-releasing hormone, Thyroid releasing hormone, 252: PN: WO2010033207 SEQID: 378 claimed protein, TSH-releasing factor, Thyrotropic hormone-releasing hormone. CAS No. 24305-27-9. IUPAC Name: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide. Molecular Formula: C16H22N6O4. Mole Weight: 362.38. Catalog: APS24305279. SMILES: NC (=O)[C@@H]1CCCN1C (=O)[C@H] (Cc2c[nH]cn2)NC (=O)[C@@H]3CCC (=O)N3. Format: Neat. |  |
| Protirelin acetate | Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone acetate; TRH acetate. CAS No. 120876-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P0002A. | |
| pyroglutamyl-peptidase II | Highly specific for thyrotropin releasing hormone (pyroglutamyl-histidyl-prolylamide). Will not cleave the pyroglutamyl-histidyl bond of luteinizing hormone releasing hormone. Found in serum and brain. Inhibited by metal chelators. In peptidase family M1 (membrane alanyl aminopeptidase family). Group: Enzymes. Synonyms: thyroliberinase; pyroglutamyl aminopeptidase II; thyrotropin-releasing factor pyroglutamate aminopeptidase; pyroglutamate aminopeptidase II; pyroglutamyl peptidase II; thyroliberin-hydrolyzing pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading peptidase; TRH aminopeptidase. Enzyme Commission Number: EC 3.4.19.6. CAS No. 60063-88-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4090; pyroglutamyl-peptidase II; EC 3.4.19.6; 60063-88-9; thyroliberinase; pyroglutamyl aminopeptidase II; thyrotropin-releasing factor pyroglutamate aminopeptidase; pyroglutamate aminopeptidase II; pyroglutamyl peptidase II; thyroliberin-hydrolyzing pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase; thyrotropin-releasing hormone-degrading peptidase; TRH aminopeptidase. Cat No: EXWM-4090. | |
| Rovatirelin | Rovatirelin, a novel synthetic agent that mimics the actions of thyrotropin-releasing hormone (TRH), binds to the human TRH receptor with higher affinity (Ki=702nM) than taltirelin (Ki=3877nM). Rovatirelin may have an orally effective therapeutic potential in patients with SCD. Synonyms: S-0373; S 0373; S0373. (4S,5S)-5-methyl-N-((S)-1-((R)-2-methylpyrrolidin-1-yl)-1-oxo-4-(thiazol-4-yl)butan-2-yl)-2-oxooxazolidine-4-carboxamide4-Oxazolidinecarboxamide, 5-methyl-N-[2-(2-methyl-1-pyrrolidinyl)-2-oxo-1-(4-thiazolylmethyl)ethyl]-2-oxo-, [4S-[4α[R*(S*)],5α]]-; UNII-9DL0X410PY; Ravatirelin [INN]; RAVATIRELIN; 9DL0X410PY; SCHEMBL14306794; (4S,5S)-5-methyl-N-((2S)-1-((2R)-2-methylpyrrolidin-1-yl)-1-oxo-3-((1,3-thiazol-4-yl)methyl)propan-2-yl)-2-oxo-1,3-oxazolidine-4-carboxamide; 204386-76-5. Grades: >98%. CAS No. 204386-76-5. Molecular formula: C16H22N4O4S. Mole weight: 366.436. | |
| Taltirelin | Taltirelin is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Synonyms: N-[[(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-L-prolinamide; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide; (4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinecarbonyl-L-histidyl-L-prolinamide; Ceredist; TA 0910; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide. Grades: >98%. CAS No. 103300-74-9. Molecular formula: C17H23N7O5. Mole weight: 405.41. | |
| Taltirelin | Taltirelin (TA-0910) is an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist ( IC 50 at 910 nM). Taltirelin can cross the blood-brain barrier. Taltirelin stimulates an increase in cytosolic Ca 2+ concentration (Ca 2+ release) with an EC 50 value of 36 nM. Taltirelin increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons treated with MPP+ (HY-W008719) or Rotenone (HY-B1756). Taltirelin has neuroprotective effects in both cellular and animal models of Parkinson's disease. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-0910. CAS No. 103300-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0596. | |
| Taltirelin acetate | Taltirelin acetate (TA-0910) is an acetate form of Taltirelin (TA-0910). Taltirelin (TA-0910) is an orally effective analogue of thyrotropin releasing hormone (TRH) and a TRH receptor (TRH-R) superagonist ( IC 50 at 910 nM). Taltirelin can cross the blood-brain barrier. Taltirelin stimulates an increase in cytosolic Ca 2+ concentration (Ca 2+ release) with an EC 50 value of 36 nM. Taltirelin increases cell viability and reduces apoptosis in SH-SY5Y cells and primary rat mesencephalic neurons treated with MPP+ (HY-W008719) or Rotenone (HY-B1756). Taltirelin has neuroprotective effects in both cellular and animal models of Parkinson's disease. Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-0910 acetate. CAS No. 1549593-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0596A. | |
| Taltirelin Hydrate | Taltirelin hydrate is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Uses: Nootropic agents. Synonyms: N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide tetrahydrate; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide tetrahydrate; Ceredist tetrahydrate; TA 0910 tetrahydrate; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide tetrahydrate; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide tetrahydrate. Grades: ≥95%. CAS No. 201677-75-0. Molecular formula: C17H31N7O9. Mole weight: 477.46. | |
| Thyroid-stimulating hormone-releasing hormone | Thyroid-stimulating hormone-releasing hormone is a constitution-stimulating hormone produced by hypothalamic neurons. It can stimulate the anterior pituitary to release thyroid-stimulating hormone and prolactin. Uses: Hormones. Synonyms: Protirelin; TSH-RF; pGlu-His-Pro-NH2; {pGLU}HP-NH2; Thyroliberin; L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-; 5-Oxo-L-prolyl-L-histidyl-L-prolinamide; Thyrotropin-releasing factor; (Pyro)-L-glutamic acid-L-histidine-L-proline-NH2; L-Pyroglutamyl-L-histidyl-L-prolinamide; Abbott 38579; Antepan; FDA 1725; Lopremone; Prem; Relefact TRH; Rifathyroin; Rifotironin; Ro 8-6270/9; Stimu TSH; Synthetic thyrotropin-releasing factor; Synthetic thyrotropin-releasing hormone; Synthetic TRF; Synthetic TRH; Thypinone; Thyrefact; Thyroid releasing hormone; Thyroid-stimulating hormone-releasing factor; TRF; TRH; TSH-releasing factor; TSH-releasing hormone. Grades: 95%. CAS No. 24305-27-9. Molecular formula: C16H22N6O4. Mole weight: 362.38. | |
| Thyroliberin acetate salt | Thyroliberin acetate salt is a highly conserved neuropeptide that stimulates the release of thyrotropin and prolactin and plays a hormonal role in controlling thyroid-stimulating hormone (TSH) levels and neuromodulatory functions. Synonyms: Lopremone Acetate; TRH Acetate; Thyroliberin Acetate; TRF Acetate; pGlu-His-Pro-NH2 Acetate; Synthetic thyrotropin-releasing hormone Acetate; Protirelin acetate; Protirelin monoacetate; H-Pyr-His-Pro-NH2.CH3CO2H; Pyr-HP-NH2.CH3CO2H; L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, acetate (1:1); L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-, monoacetate; Thyrotropin-releasing factor (pig), monoacetate; Pyroglutamylhistidylprolinamide acetate; Thyrotropin-releasing hormone acetate; L-pyroglutamyl-L-histidyl-L-prolinamide acetic acid. Grades: ≥95%. CAS No. 25575-91-1. Molecular formula: C18H26N6O6. Mole weight: 422.44. | |
| Trh-gly | Trh-gly. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GLP-HIS-PRO-GLY;PYR-HIS-PRO-GLY-OH;PYR-HIS-PRO-GLY;PE-H-P-G;THYROTROPIN-RELEASING HORMONE-GLY;TRH-GLY;pglu-his-pro-gly. Product Category: Heterocyclic Organic Compound. CAS No. 85344-77-0. Molecular formula: C18H24N6O6. Mole weight: 420.42. Purity: 0.96. IUPACName: 2-[[1-[3-(1H-imidazol-5-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid. Canonical SMILES: C1CC(N(C1)C(=O)C(CC2=CN=CN2)NC(=O)C3CCC(=O)N3)C(=O)NCC(=O)O. Density: 1.461g/cm³. Product ID: ACM85344770. Alfa Chemistry ISO 9001:2015 Certified. Categories: Triglyceride. |  |
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