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Labeled Ticagrelor , the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. CAS No. 1265911-55-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Ticagrelor-[d7]
A labelled form of Ticagrelor which inhibits adenosine uptake in the dog MDCK cells, and rat hepatoma H4IIE cells. Synonyms: (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-D1,2-Cyclopentanediolifluorophenyl)cyclopropyl]amino]-5-(propylthio-d7)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol; AR-C 126532XX-d7; AZD 6140-d7. Grade: >95%. CAS No. 1265911-55-4. Molecular formula: C23H21D7F2N6O4S. Mole weight: 529.62.
Ticagrelor EP Impurity E hydrochloride
Ticagrelor EP Impurity E hydrochloride is a conformationally restricted phenethylamine. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402222-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-I0180A.
Ticagrelor Impurity 13
Ticagrelor Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxamide. CAS No. 1006376-62-0. Molecular formula: C10H9F2NO. Mole weight: 197.18. Catalog: APB1006376620.
Ticagrelor impurity 2
Ticagrelor impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1414348-35-8. Molecular formula: C9H9F2N. Mole weight: 169.17. Catalog: APB1414348358.
Ticagrelor Impurity H
Ticagrelor Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,2S,3R,5S)-3-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol. CAS No. 1251765-07-7. Molecular formula: C14H22N6O4S. Mole weight: 370.43. Catalog: APB1251765077.
Ticagrelor Impurity H
Ticagrelor Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402150-10-0. Molecular formula: C25H30F2N6O5S. Mole weight: 564.61. Catalog: APB1402150100.
Ticagrelor Isomer 3
Ticagrelor Isomer 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1858268-00-4. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57. Catalog: APB1858268004.
Ticagrelor Sulfoxide (Mixture of Diastereomers)
Ticagrelor Sulfoxide (Mixture of Diastereomers). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1644461-85-7. Pack Sizes: 2.5MG. IUPAC Name: (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfinyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol. Molecular formula: C23H28F2N6O5S. Mole weight: 538.57. Catalog: APS1644461857. SMILES: CCCS(=O)c1nc(N[C@@H]2C[C@H]2c3ccc(F)c(F)c3)c4nnn([C@@H]5C[C@H](OCCO)[C@@H](O)[C@H]5O)c4n1. Format: Neat. Shipping: Room Temperature.
1,2-diepi-ent-Ticagrelor
1,2-diepi-ent-Ticagrelor is the 1,2-diepi enantiomer of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
Worldwide
1,2-diepi-ent-Ticagrelor-d7
1,2-diepi-ent-Ticagrelor-d7 is the isotope labelled analog of 1,2-diepi-ent-Ticagrelor (T437705); the 1,2-diepi enantiomer of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C23H21D7F2N6O4S, Molecular Weight: 529.61. US Biological Life Sciences.
Worldwide
1S-epi-Ticagrelor
1S-epi-Ticagrelor is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
Worldwide
2R-epi-Ticagrelor
2R-epi-Ticagrelor is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
Deshydroxyethoxy Ticagrelor-d7. Group: Biochemicals. Alternative Names: AR-C 124910XX-d7. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C21H17D7F2N6O3S, Molecular Weight: 485.56. US Biological Life Sciences.
Worldwide
ent-Ticagrelor
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: (1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol; Ticagrelor impurity J. CAS No. 2096989-55-6. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57.
1, 2-Difluoro-4- [ (1R, 2S) -2-nitrocyclopropyl] benzene is an intermediate in synthesizing (1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (D445460), which is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1345413-24-2. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H7F2NO2, Molecular Weight: 199.15. US Biological Life Sciences.
Worldwide
1-(3,4-Difluorophenyl)-3-nitro-1-propanone
1-(3,4-Difluorophenyl)-3-nitro-1-propanone is an intermediate in synthesizing (1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (D445460), which is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1345413-22-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H7F2NO3, Molecular Weight: 215.15. US Biological Life Sciences.
Worldwide
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine is a ticagrelor (T437700) related compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 1414348-35-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H9F2N, Molecular Weight: 169.17. US Biological Life Sciences.
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide is a useful synthetic intermediate in the synthesis of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is also used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. CAS No. 378236-67-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C10H7F2N3O, Molecular Weight: 223.18. US Biological Life Sciences.
(1R, 2R) -2- (3, 4-Difluorophenyl) cyclopropane carboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1006376-62-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H9F2NO, Molecular Weight: 197.181. US Biological Life Sciences.
(1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropanamine Hydrochloride was used to study potential new impurities in ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1402222-66-5. Pack Sizes: 2.5g, 10g. Molecular Formula: C9H9F2N; HCl, Molecular Weight: 169.173645999999. US Biological Life Sciences.
(1R, 2S) -2- (3-Chloro-4-fluorophenyl) cyclopropan-1-amine is an impurity of Ticagrelor, a reversible oral P2Y12 receptor antagonist used to treat acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C9H10Cl2FN, Molecular Weight: 222.09. US Biological Life Sciences.
Worldwide
(1R, 2S) -2- (3-Fluorophenyl) cyclopropanamine
(1R, 2S) -2- (3-Fluorophenyl) cyclopropanamine is an impurity of Ticagrelor (T437700), [274693-27-5]. Group: Biochemicals. Grades: Highly Purified. CAS No. 220353-83-3. Pack Sizes: 10mg, 2.5mg. Molecular Formula: C9H10FN, Molecular Weight: 151.18. US Biological Life Sciences.
Worldwide
(1R, 2S) -2- (4-Fluorophenyl) cyclopropanamine
(1R, 2S) -2- (4-Fluorophenyl) cyclopropanamine is an impurity of Ticagrelor (T437700), [274693-27-5]. Group: Biochemicals. Grades: Highly Purified. CAS No. 220349-80-4. Pack Sizes: 10mg, 2.5mg. Molecular Formula: C9H10FN, Molecular Weight: 151.18. US Biological Life Sciences.
Worldwide
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1345413-20-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H9F2N. US Biological Life Sciences.
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine Hydrochloride is the hydrochloride salt of (1S, 2R)-2- (3, 4-Difluorophenyl)-cyclopropanamine (D445460), which is used to prepare Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H9F2N; HCl. US Biological Life Sciences.
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (S)-(+)-Mandelic Acid is used as an intermediate to prepare Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9F2N; C8H8O3, Molecular Weight: 169.1715215. US Biological Life Sciences.
Worldwide
(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine
(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine is an isomer of (1R, 2S) -2- (3, 4-difluorophenyl) cyclopropylamine (D447030), which is a key intermediate in the synthesis of Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1459719-81-3. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H9F2N, Molecular Weight: 169.17. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-[[3-[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]-5- (propylthio) -3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-7-yl]amino]-5- (2-hydroxyethoxy) -1, 2-cyclopentanediol is an impurity of Ticagrelor (T437700) which is an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1788033-05-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3- (5-amino-6-chloro-2- (propylthio) pyrimidin-4-ylamino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol is an impurity of Ticagrelor (T437700) which is an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1402150-32-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H23ClN4O4S, Molecular Weight: 378.87. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3- (5-Amino-6-chloro-2- (propylthio) pyrimidin-4-ylamino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol-d7 is the labelled analogue of (1S, 2S, 3R, 5S) -3- (5-Amino-6-chloro-2- (propylthio) pyrimidin-4-ylamino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol which is an impurity of Ticagrelor (T437700); an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H16D7ClN4O4S, Molecular Weight: 385.92. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-[7-[[ (1R, 2S) -2- (2, 3-difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-3-yl]-5- (2-hydroxyethoxy) -1, 2-cyclopentanediol is an impurity of Ticagrelor (T437700) which is a anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643378-48-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-[7-[[ (1R, 2S) -2- (4-fluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-3-yl]-5- (2-hydroxyethoxy) -1, 2-cyclopentanediol is an impurity of Ticagrelor (T437700) which is an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643378-47-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H29FN6O4S, Molecular Weight: 504.58. US Biological Life Sciences.
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol is an intermediate in the synthesis of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 1354945-69-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H20ClN5O4S. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-Amino-5- (2-hydroxyethoxy) cyclopentane-1, 2-diol Hydrochloride is used in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H16ClNO4, Molecular Weight: 213.66. US Biological Life Sciences.
(1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-methoxy-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-1,2-cyclopentanediol is an intermediate in the synthesis of (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol which is used in preparation of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 2024557-22-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23N5O5S. US Biological Life Sciences.
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: 2,2'-(((3aR,3a'R,4S,4'S,6R,6aS,6'R,6a'S)-6,6'-((5-Nitro-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))diethanol; B0027-284940. CAS No. 1882095-50-2. Molecular formula: C27H43N5O10S. Mole weight: 629.72.
2-[[(3aR,4R,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol (R,R)-Tartrate Salt
2-[[(3aR,4R,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol (R,R)-Tartrate Salt is an impurity of Ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C14H25NO10, Molecular Weight: 367.35. US Biological Life Sciences.
2- [ [ (3aR, 4S, 6R, 6aS) -6- [ [5-Amino-6-chloro-2- (propylthio) -4-pyrimidinyl] amino] tetrahydro-2, 2-dimethyl-4H-cyclopenta-1, 3-dioxol-4-yl] oxy] ethanol is used as a reagent in the synthesis of Ticagrelor (T437700) derivatives as antiplatelet agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 376608-74-1. Pack Sizes: 1g, 5g. Molecular Formula: C17H27ClN4O4S. US Biological Life Sciences.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 21; Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[7-amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-. CAS No. 1858267-99-8. Molecular formula: C17H26N6O4S. Mole weight: 410.49.
2-[[(3aR,4S,6R,6aS)-6-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is used as a reagent in the synthesis of Ticagrelor (T437700); an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 376608-75-2. Pack Sizes: 100mg, 1g. Molecular Formula: C17H24ClN5O4S, Molecular Weight: 429.92. US Biological Life Sciences.
An impurity of Ticagrelor which rapidly produced and maintained greater inhibition of adenosine diphosphate (ADP)-induced platelet aggregation compared with clopidogrel without increasing major bleeding risk. Synonyms: 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioate; (2R,3R)-2,3-dihydroxybutanedioic acid; 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol. CAS No. 376608-65-0. Molecular formula: C14H25NO10. Mole weight: 367.35.
2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is an enantiomer of an intermediate for Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H19NO4, Molecular Weight: 217.26. US Biological Life Sciences.
2-[[ (3aS, 4R, 6S, 6aa) -4-[7-[[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl]-2, 2-dimethyl-tetrahydro-3aH-cyclopenta[d][1, 3]dioxol-6-yl]oxy]ethanol is an intermediate in the synthesis of Ticagrelor (T437700) which is an anticoagulant. Group: Biochemicals. Grades: Highly Purified. CAS No. 274693-26-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H32F2N6O4S. US Biological Life Sciences.
2-[[ (3aS, 4R, 6S, 6aa) -4-[7-[[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl]-2, 2-dimethyl-tetrahydro-3aH-cyclopenta[d][1, 3]dioxol-6-yl]oxy]ethanol-d7 is the labelled analogue of 2-[[ (3aS, 4R, 6S, 6aa) -4-[7-[[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl]-2, 2-dimethyl-tetrahydro-3aH-cyclopenta[d][1, 3]dioxol-6-yl]oxy]ethanol (D445305) which is an intermediate in the synthesis of Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H25D7F2N6O4S, Molecular Weight: 569.679999999999. US Biological Life Sciences.
Worldwide
2-Propylsulfanyl-pyrimidin-4-ol
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: 4(1H)-Pyrimidinone, 2-(propylthio)-. CAS No. 54460-95-6. Molecular formula: C7H10N2OS. Mole weight: 170.23.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 36. CAS No. 1456538-51-4. Molecular formula: C17H25N5O5S. Mole weight: 411.48.
3-Chloro-1-(3,4-difluorophenyl)-1-propanone
3-Chloro-1-(3,4-difluorophenyl)-1-propanone is an intermediate in synthesizing (1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (D445460), which is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1215969-79-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C9H7ClF2O, Molecular Weight: 204.6. US Biological Life Sciences.
Worldwide
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 4,6-dichloro-2-(propylthio)pyrimidin-5-amine. Grade: 95 %. CAS No. 145783-15-9. Molecular formula: C7H9Cl2N3S. Mole weight: 238.14.
4,6-Dichloro-5-nitro-2-propylthiopyrimidine
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine; 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine. Grade: 98.0%. CAS No. 145783-14-8. Molecular formula: C7H7Cl2N3O2S. Mole weight: 268.12.
4-Chloro-2-propylsulfanyl-pyrimidine
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: Pyrimidine, 4-chloro-2-(propylthio)-. CAS No. 1351990-36-7. Molecular formula: C7H9ClN2S. Mole weight: 188.673.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 35. CAS No. 1427523-93-0. Molecular formula: C16H15ClF2N4O2S. Mole weight: 400.83.
AR-C124910XX-N-Glucuronide
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and compared with clopidogrel will result in a lower risk of recurrent thrombotic events in a broad patient population with ACS and that this result can be achieved with a clinically acceptable bleeding rate and overall safety profile. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65.
AR-C124910XX-O-Glucuronide
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist ticagrelor and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65.
Elinogrel
Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRT 060128; PRT-060128; PRT060128; Elinogrel. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.94. Purity: >98%. IUPACName: 5-chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide. Canonical SMILES: O=C(NC1=CC=C(N2C(NC3=C(C=C(F)C(NC)=C3)C2=O)=O)C=C1)NS(=O)(C4=CC=C(Cl)S4)=O. Product ID: ACM936500946-1. Alfa Chemistry ISO 9001:2015 Certified.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, ethyl ester, (1R,2R)-; Ticagrelor impurity 23. CAS No. 1006376-61-9. Molecular formula: C12H12F2O2. Mole weight: 226.22.
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