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Labeled Ticagrelor , the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. CAS No. 1265911-55-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Ticagrelor-[d7]
A labelled form of Ticagrelor which inhibits adenosine uptake in the dog MDCK cells, and rat hepatoma H4IIE cells. Synonyms: (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-D1,2-Cyclopentanediolifluorophenyl)cyclopropyl]amino]-5-(propylthio-d7)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol; AR-C 126532XX-d7; AZD 6140-d7. Grade: >95%. CAS No. 1265911-55-4. Molecular formula: C23H21D7F2N6O4S. Mole weight: 529.62.
Ticagrelor EP Impurity E hydrochloride
Ticagrelor EP Impurity E hydrochloride is a conformationally restricted phenethylamine. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402222-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-I0180A.
Ticagrelor Impurity 13
Ticagrelor Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxamide. CAS No. 1006376-62-0. Molecular formula: C10H9F2NO. Mole weight: 197.18. Catalog: APB1006376620.
Ticagrelor impurity 2
Ticagrelor impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1414348-35-8. Molecular formula: C9H9F2N. Mole weight: 169.17. Catalog: APB1414348358.
Ticagrelor Impurity H
Ticagrelor Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,2S,3R,5S)-3-(7-amino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol. CAS No. 1251765-07-7. Molecular formula: C14H22N6O4S. Mole weight: 370.43. Catalog: APB1251765077.
Ticagrelor Impurity H
Ticagrelor Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1402150-10-0. Molecular formula: C25H30F2N6O5S. Mole weight: 564.61. Catalog: APB1402150100.
Ticagrelor Isomer 3
Ticagrelor Isomer 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1858268-00-4. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57. Catalog: APB1858268004.
Ticagrelor Sulfoxide (Mixture of Diastereomers)
Ticagrelor Sulfoxide (Mixture of Diastereomers). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1644461-85-7. Pack Sizes: 2.5MG. IUPAC Name: (1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfinyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol. Molecular formula: C23H28F2N6O5S. Mole weight: 538.57. Catalog: APS1644461857. SMILES: CCCS(=O)c1nc(N[C@@H]2C[C@H]2c3ccc(F)c(F)c3)c4nnn([C@@H]5C[C@H](OCCO)[C@@H](O)[C@H]5O)c4n1. Format: Neat. Shipping: Room Temperature.
1,2-diepi-ent-Ticagrelor
1,2-diepi-ent-Ticagrelor is the 1,2-diepi enantiomer of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
Worldwide
1,2-diepi-ent-Ticagrelor-d7
1,2-diepi-ent-Ticagrelor-d7 is the isotope labelled analog of 1,2-diepi-ent-Ticagrelor (T437705); the 1,2-diepi enantiomer of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C23H21D7F2N6O4S, Molecular Weight: 529.61. US Biological Life Sciences.
Worldwide
1S-epi-Ticagrelor
1S-epi-Ticagrelor is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
Worldwide
2R-epi-Ticagrelor
2R-epi-Ticagrelor is an impurity of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
Deshydroxyethoxy Ticagrelor-d7. Group: Biochemicals. Alternative Names: AR-C 124910XX-d7. Grades: Highly Purified. Pack Sizes: 500ug. Molecular Formula: C21H17D7F2N6O3S, Molecular Weight: 485.56. US Biological Life Sciences.
Worldwide
ent-Ticagrelor
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: (1R,2R,3S,5R)-3-(7-(((1S,2R)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol; Ticagrelor impurity J. CAS No. 2096989-55-6. Molecular formula: C23H28F2N6O4S. Mole weight: 522.57.
1, 2-Difluoro-4- [ (1R, 2S) -2-nitrocyclopropyl] benzene is an intermediate in synthesizing (1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (D445460), which is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1345413-24-2. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H7F2NO2, Molecular Weight: 199.15. US Biological Life Sciences.
Worldwide
1-(3,4-Difluorophenyl)-3-nitro-1-propanone
1-(3,4-Difluorophenyl)-3-nitro-1-propanone is an intermediate in synthesizing (1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (D445460), which is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1345413-22-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H7F2NO3, Molecular Weight: 215.15. US Biological Life Sciences.
Worldwide
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine is a ticagrelor (T437700) related compound. Group: Biochemicals. Grades: Highly Purified. CAS No. 1414348-35-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H9F2N, Molecular Weight: 169.17. US Biological Life Sciences.
(1R,2R)-2-(3,4-Difluorophenyl)-cyclopropanecarbonyl Azide is a useful synthetic intermediate in the synthesis of Ticagrelor (T437700); the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is also used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. CAS No. 378236-67-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C10H7F2N3O, Molecular Weight: 223.18. US Biological Life Sciences.
(1R, 2R) -2- (3, 4-Difluorophenyl) cyclopropane carboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1006376-62-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H9F2NO, Molecular Weight: 197.181. US Biological Life Sciences.
(1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropanamine Hydrochloride was used to study potential new impurities in ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1402222-66-5. Pack Sizes: 2.5g, 10g. Molecular Formula: C9H9F2N; HCl, Molecular Weight: 169.173645999999. US Biological Life Sciences.
(1R, 2S) -2- (3-Chloro-4-fluorophenyl) cyclopropan-1-amine is an impurity of Ticagrelor, a reversible oral P2Y12 receptor antagonist used to treat acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 50mg. Molecular Formula: C9H10Cl2FN, Molecular Weight: 222.09. US Biological Life Sciences.
Worldwide
(1R, 2S) -2- (3-Fluorophenyl) cyclopropanamine
(1R, 2S) -2- (3-Fluorophenyl) cyclopropanamine is an impurity of Ticagrelor (T437700), [274693-27-5]. Group: Biochemicals. Grades: Highly Purified. CAS No. 220353-83-3. Pack Sizes: 10mg, 2.5mg. Molecular Formula: C9H10FN, Molecular Weight: 151.18. US Biological Life Sciences.
Worldwide
(1R, 2S) -2- (4-Fluorophenyl) cyclopropanamine
(1R, 2S) -2- (4-Fluorophenyl) cyclopropanamine is an impurity of Ticagrelor (T437700), [274693-27-5]. Group: Biochemicals. Grades: Highly Purified. CAS No. 220349-80-4. Pack Sizes: 10mg, 2.5mg. Molecular Formula: C9H10FN, Molecular Weight: 151.18. US Biological Life Sciences.
Worldwide
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1345413-20-8. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H9F2N. US Biological Life Sciences.
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine Hydrochloride is the hydrochloride salt of (1S, 2R)-2- (3, 4-Difluorophenyl)-cyclopropanamine (D445460), which is used to prepare Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C9H9F2N; HCl. US Biological Life Sciences.
(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (S)-(+)-Mandelic Acid is used as an intermediate to prepare Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H9F2N; C8H8O3, Molecular Weight: 169.1715215. US Biological Life Sciences.
Worldwide
(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine
(1S,2S)-2-(3,4-Difluorophenyl)-cyclopropanamine is an isomer of (1R, 2S) -2- (3, 4-difluorophenyl) cyclopropylamine (D447030), which is a key intermediate in the synthesis of Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1459719-81-3. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C9H9F2N, Molecular Weight: 169.17. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-[[3-[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]-5- (propylthio) -3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-7-yl]amino]-5- (2-hydroxyethoxy) -1, 2-cyclopentanediol is an impurity of Ticagrelor (T437700) which is an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1788033-05-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3- (5-amino-6-chloro-2- (propylthio) pyrimidin-4-ylamino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol is an impurity of Ticagrelor (T437700) which is an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1402150-32-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H23ClN4O4S, Molecular Weight: 378.87. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3- (5-Amino-6-chloro-2- (propylthio) pyrimidin-4-ylamino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol-d7 is the labelled analogue of (1S, 2S, 3R, 5S) -3- (5-Amino-6-chloro-2- (propylthio) pyrimidin-4-ylamino) -5- (2-hydroxyethoxy) cyclopentane-1, 2-diol which is an impurity of Ticagrelor (T437700); an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H16D7ClN4O4S, Molecular Weight: 385.92. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-[7-[[ (1R, 2S) -2- (2, 3-difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-3-yl]-5- (2-hydroxyethoxy) -1, 2-cyclopentanediol is an impurity of Ticagrelor (T437700) which is a anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643378-48-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28F2N6O4S, Molecular Weight: 522.57. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-[7-[[ (1R, 2S) -2- (4-fluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-1, 2, 3-triazolo[4, 5-d]pyrimidin-3-yl]-5- (2-hydroxyethoxy) -1, 2-cyclopentanediol is an impurity of Ticagrelor (T437700) which is an anticoagulant used in the treatment of acute coronary syndromes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1643378-47-5. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H29FN6O4S, Molecular Weight: 504.58. US Biological Life Sciences.
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol is an intermediate in the synthesis of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 1354945-69-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H20ClN5O4S. US Biological Life Sciences.
(1S, 2S, 3R, 5S) -3-Amino-5- (2-hydroxyethoxy) cyclopentane-1, 2-diol Hydrochloride is used in the synthesis of Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H16ClNO4, Molecular Weight: 213.66. US Biological Life Sciences.
(1S,2S,3S,5R)-3-(2-Hydroxyethoxy)-5-[7-methoxy-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-1,2-cyclopentanediol is an intermediate in the synthesis of (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol which is used in preparation of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Group: Biochemicals. Grades: Highly Purified. CAS No. 2024557-22-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C15H23N5O5S. US Biological Life Sciences.
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: 2,2'-(((3aR,3a'R,4S,4'S,6R,6aS,6'R,6a'S)-6,6'-((5-Nitro-2-(propylthio)pyrimidine-4,6-diyl)bis(azanediyl))bis(2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxole-6,4-diyl))bis(oxy))diethanol; B0027-284940. CAS No. 1882095-50-2. Molecular formula: C27H43N5O10S. Mole weight: 629.72.
2-[[(3aR,4R,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol (R,R)-Tartrate Salt
2-[[(3aR,4R,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol (R,R)-Tartrate Salt is an impurity of Ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 10mg. Molecular Formula: C14H25NO10, Molecular Weight: 367.35. US Biological Life Sciences.
2- [ [ (3aR, 4S, 6R, 6aS) -6- [ [5-Amino-6-chloro-2- (propylthio) -4-pyrimidinyl] amino] tetrahydro-2, 2-dimethyl-4H-cyclopenta-1, 3-dioxol-4-yl] oxy] ethanol is used as a reagent in the synthesis of Ticagrelor (T437700) derivatives as antiplatelet agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 376608-74-1. Pack Sizes: 1g, 5g. Molecular Formula: C17H27ClN4O4S. US Biological Life Sciences.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 21; Ethanol, 2-[[(3aR,4S,6R,6aS)-6-[7-amino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-. CAS No. 1858267-99-8. Molecular formula: C17H26N6O4S. Mole weight: 410.49.
2-[[(3aR,4S,6R,6aS)-6-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is used as a reagent in the synthesis of Ticagrelor (T437700); an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 376608-75-2. Pack Sizes: 100mg, 1g. Molecular Formula: C17H24ClN5O4S, Molecular Weight: 429.92. US Biological Life Sciences.
An impurity of Ticagrelor which rapidly produced and maintained greater inhibition of adenosine diphosphate (ADP)-induced platelet aggregation compared with clopidogrel without increasing major bleeding risk. Synonyms: 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-ethanol (2R,3R)-2,3-dihydroxybutanedioate; (2R,3R)-2,3-dihydroxybutanedioic acid; 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol. CAS No. 376608-65-0. Molecular formula: C14H25NO10. Mole weight: 367.35.
2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol is an enantiomer of an intermediate for Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist that provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C10H19NO4, Molecular Weight: 217.26. US Biological Life Sciences.
2-[[ (3aS, 4R, 6S, 6aa) -4-[7-[[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl]-2, 2-dimethyl-tetrahydro-3aH-cyclopenta[d][1, 3]dioxol-6-yl]oxy]ethanol is an intermediate in the synthesis of Ticagrelor (T437700) which is an anticoagulant. Group: Biochemicals. Grades: Highly Purified. CAS No. 274693-26-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H32F2N6O4S. US Biological Life Sciences.
2-[[ (3aS, 4R, 6S, 6aa) -4-[7-[[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl]-2, 2-dimethyl-tetrahydro-3aH-cyclopenta[d][1, 3]dioxol-6-yl]oxy]ethanol-d7 is the labelled analogue of 2-[[ (3aS, 4R, 6S, 6aa) -4-[7-[[ (1R, 2S) -2- (3, 4-Difluorophenyl) cyclopropyl]amino]-5- (propylthio) -3H-[1, 2, 3]triazolo[4, 5-d]pyrimidin-3-yl]-2, 2-dimethyl-tetrahydro-3aH-cyclopenta[d][1, 3]dioxol-6-yl]oxy]ethanol (D445305) which is an intermediate in the synthesis of Ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H25D7F2N6O4S, Molecular Weight: 569.679999999999. US Biological Life Sciences.
Worldwide
2-Propylsulfanyl-pyrimidin-4-ol
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: 4(1H)-Pyrimidinone, 2-(propylthio)-. CAS No. 54460-95-6. Molecular formula: C7H10N2OS. Mole weight: 170.23.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 36. CAS No. 1456538-51-4. Molecular formula: C17H25N5O5S. Mole weight: 411.48.
3-Chloro-1-(3,4-difluorophenyl)-1-propanone
3-Chloro-1-(3,4-difluorophenyl)-1-propanone is an intermediate in synthesizing (1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanamine (D445460), which is an intermediate used to prepare ticagrelor (T437700). Group: Biochemicals. Grades: Highly Purified. CAS No. 1215969-79-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C9H7ClF2O, Molecular Weight: 204.6. US Biological Life Sciences.
Worldwide
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 4,6-dichloro-2-(propylthio)pyrimidin-5-amine. Grade: 95 %. CAS No. 145783-15-9. Molecular formula: C7H9Cl2N3S. Mole weight: 238.14.
4,6-Dichloro-5-nitro-2-propylthiopyrimidine
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 4,6-dichloro-5-nitro-2-(propylthio)pyrimidine; 4,6-dichloro-5-nitro-2-propylsulfanylpyrimidine. Grade: 98.0%. CAS No. 145783-14-8. Molecular formula: C7H7Cl2N3O2S. Mole weight: 268.12.
4-Chloro-2-propylsulfanyl-pyrimidine
An impurity of Ticagrelor, which is the first reversible oral P2Y12 receptor antagonist and has favorable pharmacokinetics and pharmacodynamics, including rapid peaking of plasma levels (1.5-3 hours) and rapid onset of antiplatelet effects (within 2 hours). Synonyms: Pyrimidine, 4-chloro-2-(propylthio)-. CAS No. 1351990-36-7. Molecular formula: C7H9ClN2S. Mole weight: 188.673.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Ticagrelor impurity 35. CAS No. 1427523-93-0. Molecular formula: C16H15ClF2N4O2S. Mole weight: 400.83.
AR-C124910XX-N-Glucuronide
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and compared with clopidogrel will result in a lower risk of recurrent thrombotic events in a broad patient population with ACS and that this result can be achieved with a clinically acceptable bleeding rate and overall safety profile. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65.
AR-C124910XX-O-Glucuronide
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist ticagrelor and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: 6-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)(5-(propylthio)-3-((1R,2S,3R,4S)-2,3,4-trihydroxycyclopentyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)amino)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grade: > 95%. Molecular formula: C27H32F2N6O9S. Mole weight: 654.65.
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and offset of action. Alternative Names: Kengreal. AR-C69931XX. Cangrelor free acid. CAS No. 163706-06-7. Product ID: API163706067. Molecular formula: C17H25Cl2F3N5O12P3S2. Mole weight: 776.4. SMILES: CSCCNC1=C2C(=NC(=N1)SCCC(F)(F)F)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(C(P(=O)(O)O)(Cl)Cl)O)O)O. Appearance: Solid Powder. Category: Active Pharmaceutical Ingredients.
Elinogrel
Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRT 060128; PRT-060128; PRT060128; Elinogrel. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.94. Purity: >98%. IUPACName: 5-chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide. Canonical SMILES: O=C(NC1=CC=C(N2C(NC3=C(C=C(F)C(NC)=C3)C2=O)=O)C=C1)NS(=O)(C4=CC=C(Cl)S4)=O. Product ID: ACM936500946-1. Alfa Chemistry ISO 9001:2015 Certified.
An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor. Synonyms: Cyclopropanecarboxylic acid, 2-(3,4-difluorophenyl)-, ethyl ester, (1R,2R)-; Ticagrelor impurity 23. CAS No. 1006376-61-9. Molecular formula: C12H12F2O2. Mole weight: 226.22.
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