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α-Tocotrienol is an isoform of vitamin E and found in vegetables, fruits, seeds, nuts, grains, and oils. Vitamin E plays a role as an antioxidant , in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection. Uses: Scientific research. Group: Natural products. CAS No. 58864-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129459.
β-Tocotrienol
β-Tocotrienol is isolated from the stem bark of Garcinia virgata. It inhibits the growth of both A549 (GI50=1.38±0.334μM) and U87MG (GI50=2.53±0.604μM) cells at rather low concentrations. β-Tocotrienol can serve as a new anticancer agent for treating human lung and brain cancers. Synonyms: (2R)-3,4-Dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-2H-1-benzopyran-6-ol; 2,5,8-Trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; D-β-Tocotrienol; ε-Tocopherol; ε-Tokoferol. Grade: 97.5%. CAS No. 490-23-3. Molecular formula: C28H42O2. Mole weight: 410.63.
β-Tocotrienol
β-Tocotrienol is one form of vitamin E. β-Tocotrienol is a less potent antioxidant than α-tocotrienol [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 490-23-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108693.
δ-Tocotrienol
δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection. Uses: Scientific research. Group: Signaling pathways. CAS No. 25612-59-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122778.
δ-Tocotrienol
δ-Tocotrienol is from palm oil. Delta-tocotrienol is a potential angiogenic inhibitor that significantly suppresses human colorectal adenocarcinoma cells (DLD-1-CM)-induced tube formation, migration, and adhesion on human umbilical vein endothelial cells. Delta-tocotrienol is a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offer a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects that protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling. Synonyms: [R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,8-Dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (R)-δ-Tocotrienol; 8-Methyltocotrienol; d-δ-Tocotrienol. Grade: 95%. CAS No. 25612-59-3. Molecular formula: C27H40O2. Mole weight: 396.60.
D-γ-Tocotrienol
γ-Tocotrienol exhibits antioxidant properties and belongs to the vitamin E family. It is naturally found in wheat germ oil and bran. In addition, α-tocopherol and γ-tocotrienol derivatives are potential lead compounds for developing anticancer and antiproliferative agents against MCF-7 and MDA-MB-231 breast cancer cells and the A549 lung cancer cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 14101-61-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C28H42O2. US Biological Life Sciences.
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D-?-Tocotrienol
analytical standard. Group: Natural compounds.
γ-Tocotrienol
γ-Tocotrienol is an active form of vitamin E. γ-tocotrienol reverses the multidrug resistance (MDR) of breast cancer cells through the signaling pathway of NF-κB and P-gp. γ-Tocotrienol is also a novel radioprotector agent, can mitigate bone marrow radiation damage during targeted radionuclide treatment [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 14101-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-108694.
Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols). Group: Enzymes. Synonyms: VTE3 (gene name); 2-methyl-6-solanyl-1,4-hydroquinone methyltransferase; MPBQ/MSBQ methyltransferase; MPBQ/MSBQ MT. Enzyme Commission Number: EC 2.1.1.295. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1902; 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase; EC 2.1.1.295; VTE3 (gene name); 2-methyl-6-solanyl-1,4-hydroquinone methyltransferase; MPBQ/MSBQ methyltransferase; MPBQ/MSBQ MT. Cat No: EXWM-1902.
6-Amino-1-hexanol
6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 4048-33-3. Pack Sizes: 10g, 25g, 100g. Molecular Formula: C?H??NO. US Biological Life Sciences.
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EPI-743
EPI-743 (Vatiquinone; α-Tocotrienol quinone; PTC-743; NCT04378075) is a potent cellular oxidative stress protectant, inhibits ferroptosis in cells, which could be used for the study for mitochondrial diseases. EPI-743 is a synthetic analog of vitamin E with oral activity, targets repletion of reduced intracellular glutathione [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: α-Tocotrienol quinone; PTC-743; Vatiquinone; NCT04378075. CAS No. 1213269-98-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16772.
homogentisate geranylgeranyltransferase
Requires Mg2+ for activity. Involved in the biosynthesis of the vitamin E, tocotrienols. While the enzyme from the bacterium Synechocystis PCC 6803 has higher activity with phytyl diphosphate (EC 2.5.1.115, homogentisate phytyltransferase), the enzymes from barley, rice and wheat have only a low activity with that substrate. Group: Enzymes. Synonyms: HGGT; slr1736 (gene name). Enzyme Commission Number: EC 2.5.1.116. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2732; homogentisate geranylgeranyltransferase; EC 2.5.1.116; HGGT; slr1736 (gene name). Cat No: EXWM-2732.
tocopherol cyclase
The enzyme has been described from plants and cyanobacteria. It has similar activity with all four listed benzoquinol substrates. Involved in the biosynthesis of vitamin E (tocopherols and tocotrienols). Group: Enzymes. Synonyms: VTE1 (gene name); SXD1 (gene name); Δ/γ-tocopherol lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5625; tocopherol cyclase; EC 5.5.1.24; VTE1 (gene name); SXD1 (gene name); Δ/γ-tocopherol lyase (decyclizing). Cat No: EXWM-5625.
tocopherol O-methyltransferase
The enzymes from plants and photosynthetic bacteria have similar efficiency with the γ and Δ isomers of tocopherols and tocotrienols. Group: Enzymes. Synonyms: γ-tocopherol methyltransferase; VTE4 (gene name). Enzyme Commission Number: EC 2.1.1.95. CAS No. 84788-82-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1995; tocopherol O-methyltransferase; EC 2.1.1.95; 84788-82-9; γ-tocopherol methyltransferase; VTE4 (gene name). Cat No: EXWM-1995.
Vitamin E
Vitamin E is a generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.d-Alpha-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in...mmune function, maintaining endothelial cell integrity and balancing normal coagulation. There is no evidence that vitamin E, in physiologic or even super-physiologic, high doses, causes liver injury or jaundice. Group: Biochemicals. Alternative Names: DL-a-Tocopherol; Rac-alpha-Tocopherol; Vitamin E (DL-FORM); Tocopherol, Alpha-DL-; [2theta(4theta, 8theta)]-(+/-)-yl); 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-,[2R*(4R*,8R*)]-(+-)-2H-1-Benzopyran-6-ol; alpha-Tocopherolum; (+/-)-alpha-Tocoferol; (+/-)-alpha-T. Grades: Highly Purified. CAS No. 2074-53-5. Pack Sizes: 100g, 250g, 500g, 1Kg. Molecular Formula: C29H50O2, Molecular Weight: 430.71. US Biological Life Sciences.
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